A pre-filled auto-injector with replaceable drug and its working method

Abstract

The present invention discloses a pre-filled automatic syringe with replaceable drugs and its working method, which includes a safety device, a firing device, and a drug storage device. It includes an injection rod housing, an injection rod, an injection spring groove (2). One end of the spring seesaw is fixedly connected to a compression spring, and the other end of the compression spring is fixed to the groove and the spring seesaw. An annular protrusion is provided inside the injection rod housing. Two opposite protrusions (2) are provided on the outer side of the injection rod. The injection rod spring is sleeved on the injection rod. A downwardly protruding push rod is provided at the lower end of the injection rod; a drug storage device, which includes a cartridge. A piston is provided inside the cartridge. The bottom of the cartridge is connected to a needle, and the needle is replaceable. The lower end of the firing device is threadedly connected to the drug storage device, and the safety device is snap-connected to the upper end of the firing device.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and particularly to a pre-filled automatic syringe with replaceable drugs and its working method. Background Art

[0002] The common composition structure of medical syringes on the market now includes a syringe barrel for storing drugs, an injection push rod is provided inside one end of the syringe barrel, a needle is provided at the other end of the syringe barrel, and the needle is covered with a needle protection sleeve. When using such a syringe, the needle protection sleeve needs to be removed, and the pre-prepared drug needs to be filled into the syringe barrel, and the injection requires a medical staff to perform the injection. Non-medical staff cannot complete the injection with such a syringe. The drug needs to be filled into the syringe barrel later, so that the needle is in a non-sterile environment. In an emergency, the complicated operation process delays precious time, and the use of the syringe is very inconvenient. Summary of the Invention

[0003] Object of the Invention: The object of the present invention is to provide a pre-filled automatic syringe with replaceable drugs and its working method in view of the deficiencies of the prior art. In an emergency, according to different pre-prepared drugs, it can be directly installed and injected. Technical Solution: A pre-filled automatic syringe with replaceable drugs, characterized in that:

[0004] A safety device, which includes a top cover, a pop-up rod, and a housing. A 270-degree sector-shaped card slot is provided at the bottom of the top cover. A pair of opposite grooves (1) are provided on the card sector slot, and one of the grooves (1) is at the end of the card slot; two opposite buckles are provided at the top of the housing, and one of the buckles is stuck at one end of the sector-shaped card slot without the groove (1). A groove (1) is provided at the center position of the top of the housing. One end of the pop-up rod is placed in the groove (1). The other end of the pop-up rod is provided with a ring, the ring bulges upward in the middle, the ring is fixed inside the housing, a spring is provided between the ring and the top of the housing, and the pop-up rod passes through the spring;

[0005] A firing device, which includes an injection rod housing, an injection rod, an injection spring, and a spring toggle plate. An annular convex block is provided inside the injection rod housing. Two opposite convex grooves (2) are provided on the outer side of the injection rod. One end of the spring toggle plate is fixedly connected to a compression spring, and the other end of the compression spring is fixed to the injection spring groove and the spring toggle plate. The injection rod spring is sleeved on the injection rod. A downwardly protruding injection push rod is provided at the lower end of the injection rod;

[0006] A drug storage device, which includes a cartridge. A piston is provided inside the cartridge, and the bottom of the cartridge is connected to a needle;

[0007] The lower end of the firing device is threadedly connected to the drug storage device, and the safety device is snap-connected to the upper end of the firing device.

[0008] Further improve the above technical solution, and the needle adopts a hollow microneedle array structure.

[0009] Furthermore, a medicine viewing window is provided on the side of the medicine storage device for observing the remaining amount of the medicine in the medicine storage device.

[0010] Furthermore, the medicine storage device is marked with multiple colors, and different medicines are loaded according to different colors.

[0011] Furthermore, the needles are circularly distributed with 4 - 8 needles on a circle with a diameter of 1 cm.

[0012] Furthermore, the length of the needles is between 0.2 mm and 4 mm.

[0013] Furthermore, the thickness of the needles is 27G - 34G.

[0014] Furthermore, the medicine storage device is provided with a microneedle protective cover, and the microneedle protective cover is snap - connected to the medicine storage device.

[0015] Furthermore, a silica gel pad is provided inside the microneedle protective cover.

[0016] Advantageous effects: Compared with the prior art, the advantages of the present invention are as follows: According to different current situations, the corresponding medicine storage device is selected and directly installed on the firing device for injection. A multi - channel microneedle is adopted. In a complex environment, the wounded can quickly, without liquid leakage, painlessly, safely and conveniently inject the first - aid medicine vertically into the subcutaneous tissue at parts such as the abdomen, arm, thigh, buttocks, etc. through one - hand operation, thus realizing self - rescue. Description of the Drawings

[0017] Figure 1 is a schematic diagram of the working principle of the pre - filled automatic syringe with replaceable medicine of the present invention;

[0018] Figure 2 is a schematic diagram of the structure of the pre - filled automatic syringe with replaceable medicine of the present invention;

[0019] Figure 3 is a schematic diagram of the structure of the pre - filled automatic syringe with replaceable medicine of the present invention after injection;

[0020] Figure 4 is a schematic diagram of the structure of the pre - filled automatic syringe with replaceable medicine of the present invention before the insurance device is activated;

[0021] Figure 5 is a schematic diagram of the structure of the pre - filled automatic syringe with replaceable medicine of the present invention after the insurance device is activated;

[0022] Figure 6 is a schematic structural diagram before the safety device of the pre-filled automatic syringe with replaceable drugs according to the present invention is activated;

[0023] Figure 7 is a schematic structural diagram after the safety device of the pre-filled automatic syringe with replaceable drugs according to the present invention is activated;

[0024] Figure 8 is a schematic structural diagram before the firing device of the pre-filled automatic syringe with replaceable drugs according to the present invention is activated;

[0025] Figure 9 is a schematic structural diagram before the drug storage device of the pre-filled automatic syringe with replaceable drugs according to the present invention is activated;

[0026] Figure 10 is a schematic structural diagram of the microneedle protective cover of the pre-filled automatic syringe with replaceable drugs according to the present invention;

[0027] Figure 11 is a schematic structural diagram of the microneedle array of the pre-filled automatic syringe with replaceable drugs according to the present invention;

[0028] Figure 12 is a schematic structural diagram of the upper part of the microneedle array of the pre-filled automatic syringe with replaceable drugs according to the present invention;

[0029] Figure 13 is a schematic external structural diagram of the pre-filled automatic syringe with replaceable drugs according to the present invention.

[0030] In the figure: 1. Safety device, 2. Firing device, 3. Drug storage device, 4. Microneedle protective cover;

[0031] 1-1. Snap, 1-2 Groove, 1-3. Outer shell, 1-4 Sector-shaped card slot, 1-5. Top cover, 1-6 Groove, 1-7. Push rod, 1-8 Spring, 1-9. Ring;

[0032] 2-1 Injection spring, 2-2 Injection rod, 2-3. Rocker spring, 2-4 Raised groove, 2-5 Spring, 2-6 Convex block, 2-7 Injection push rod;

[0033] 3-1 Piston, 3-2. Cartridge outer shell, 3-3. Cartridge, 3-4 Microneedle array needle;

[0034] 4-1 Microneedle protective cover, 4-2. Silicone pad. Detailed implementation manners

[0035] The technical solution of the present invention will be described in detail below with reference to the accompanying drawings, but the protection scope of the present invention is not limited to the described embodiments.

[0036] Example 1: As Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 , Figure 11 , Figure 12 , Figure 13 shown, the pre-filled auto-injector for replaceable drugs includes a safety device, a firing device, a drug storage device, and a microneedle protective cover. The safety device and the firing device are connected by a snap connection. The firing device and the drug storage device are connected by a threaded connection. The drug storage device and the microneedle protective cover are connected by a snap connection;

[0037] Its safety device includes a housing 1-3 and a top cover 1-5. The housing 1-3 and the top cover 1-5 are connected by a threaded connection. A pair of opposite snaps 1-1 are provided at the top of the housing 1-3. A 270° sector-shaped groove 1-4 is provided at the lower end of the top cover 1-5. Two opposite grooves 1-2 are provided inside the sector-shaped groove 1-4. One of the grooves 1-2 is located at the top of the sector-shaped groove 1-4. A groove 1-6 is also provided at the center position of the top of the housing 1-3. A push rod 1-7 is placed in the groove 1-6. The other end of the push rod 1-7 is connected to a ring 1-9. The ring 1-9 is fixed to the inner wall of the housing 1-3. A spring 1-8 is placed between the ring 1-9 and the top cover 1-5. The push rod 1-7 passes through the spring 1-8. The push rod 1-7 extends into the injection rod 2-2. At the upper port of the injection rod 2-2, there is an exhibition board that extends parallel to the surroundings. The top of the exhibition board abuts against the lower end of the ring 1-9. An injection spring 2-1 is provided inside the injection rod 2-2. The lower end of the push rod 1-7 is inside the injection spring 2-1 and has no contact with the injection spring 2-1. Two opposite outwardly protruding raised grooves 2-4 are provided on the outside of the injection rod 2-2. Springs 2-5 are respectively fixedly connected inside the raised grooves 2-4. The other ends of the springs 2-5 are respectively fixedly connected to one end of a toggle spring 2-3. The fulcrum of the toggle spring 2-3 abuts against the outer wall of the injection rod 2-2. A downwardly protruding injection push rod 2-7 is also provided at the top of the injection rod 2-2. The housing 1-3 is a ring that is thicker at the top and thinner at the bottom. The lower part of the housing 1-3 is inside the upper part of the outer shell of the injection rod 2-2. The injection push rod 2-7 abuts against the upper end of the piston 3-1. The piston 3-1 is arranged inside the upper end of the cartridge 3-3. The lower end of the cartridge 3-3 is provided with a downwardly protruding liquid medicine pipeline. The pipeline is connected to a hollow microneedle array. The microneedle protective cover 4-1 is sleeved outside the drug storage device, and the hollow microneedle array penetrates into the silica gel pad 4-2 in the microneedle protective cover 4-1;

[0038] The bottom of the cartridge 3-3 in the drug storage device is provided with a needle. The needle adopts a hollow microneedle array structure, and the needles are distributed on a circular surface with a diameter of 1 cm. To ensure reliable injection at sites such as the abdomen, arm, thigh, and buttocks, to ensure the ideal depth for the liquid medicine to enter the subcutaneous tissue rather than the muscle tissue, and to minimize pain sensation, the depth is therefore selected to be between 0.2 and 4 mm. The upper part of the needle has a flat bottom with a liquid medicine flow-through pipe in the middle, and an arc-shaped groove is adopted at the lower part of the pipe to reserve a liquid medicine storage space. The needle is 27G - 34G. Using the Bernoulli equation of fluid mechanics to calculate the ideal thrust that the spring needs to provide to inject 0.5 ml of liquid medicine into the subcutaneous tissue within 4 seconds:

[0039] Among them, the units of each parameter are:

[0040] t: s; L: m; ρ: kg / m 3 ; S: m 2

[0041]

[0042]

[0043] The calculation results of the 34G needle are as follows:

[0044]

[0045] The calculation results of the 31G needle are as follows:

[0046]

[0047] The calculation results of the 27G needle are as follows:

[0048]

[0049] Considering the friction between the transmission devices, in fact, the thrust required by the spring still needs to be accurately measured, and a redundancy should be left on the premise of ensuring the safety and reliability of the device.

[0050] After installing the required drug storage device;

[0051] When the safety device is in the locked state, one of the buckles 1-1 is at the sector-shaped card slot 1-4 at the end without the groove 1-2. At this time, the spring 1-8 is in a compressed state. There is a display board extending parallel to the surroundings at the upper port of the injection rod 2-2. The display board abuts against the lower end of the ring 1-9. There is an injection spring 2-1 inside the injection rod 2-2. The lower end of the push rod 1-7 is inside the injection spring 2-1 and has no contact with the injection spring 2-1. There are two opposite outwardly protruding raised grooves 2-4 on the outside of the injection rod 2-2. Springs 2-5 are respectively fixedly connected inside the raised grooves 2-4. The other ends of the springs 2-5 are respectively fixedly connected to one end of the rocker spring 2-3. The fulcrum of the rocker spring 2-3 fits against the outer wall of the injection rod 2-2. One end of the rocker spring 2-3 connected to the spring 2-5 abuts against the top of the convex block 2-6 inside the injection housing. The other end of the rocker spring 2-3 abuts against the display board extending outward at the top of the injection rod 2-2. There is also a downwardly protruding injection push rod 2-7 at the top of the injection rod 2-2. The housing 1-3 is a ring thicker at the top and thinner at the bottom. The lower part of the housing 1-3 is inside the upper part of the outer housing of the injection rod 2-2. The injection push rod 2-7 abuts against the upper end of the piston 3-1. And the piston 3-1 is located at the upper part of the cartridge 3-3. The cartridge is arranged inside the cartridge housing 3-2. The hollow microneedle array is fixed in the silica gel pad 4-2 in the microneedle protective sleeve 4-1.

[0052] When the housing 1-3 is rotated clockwise by 90°, the safety device is in the unlocked state. One of the buckles 1-1 is at the sector-shaped card slot 1-4 at the end with the groove 1-2. At this time, the spring 1-8 drives the housing 1-3 to pop up upward until the lower end of the push rod 1-7 is stuck at the position of the ring 1-9. The microneedle protective sleeve 4-1 is removed. One end of the microneedle is placed on the skin surface. The top cover 1-5 is pressed to make the needle pierce the skin. At the same time, it drives the housing 1-3 to move downward. The lower end of the housing 1-3 squeezes the lower part of the rocker spring 2-3, so that the spring 2-5 inside the lower end inner side of the rocker spring 2-3 is compressed inward. When the lower end of the rocker spring 2-3 leaves the convex block 2-6 inside the injection housing, the injection spring 2-1 inside the injection rod 2-2 pops out. Using the popping force to push the push rod at the lower end of the injection rod 2-2 to push the piston at the upper part of the cartridge arranged inside the cartridge housing 3-2, pressing the piston 3-1 to move downward to inject the liquid medicine into the subcutaneous tissue.

[0053] As described above, although the present invention has been shown and described with reference to specific preferred embodiments, it should not be construed as a limitation of the present invention itself. Various changes can be made in its form and details without departing from the spirit and scope of the present invention defined by the appended claims.

Claims

1. A pre-filled automatic syringe with replaceable drug, characterized in that: A safety device, which includes a top cover, a pop-up rod, and a housing. A 270° fan-shaped card slot is provided at the bottom of the top cover. A pair of opposite grooves (1) are provided on the fan-shaped card slot, and one of the grooves (1) is at the end of the card slot; Two opposite buckles are provided at the top of the housing, and one of the buckles is stuck at the end of the fan-shaped card slot without the groove (1). A groove (1) is provided at the center position of the top of the housing. One end of the pop-up rod is placed in the groove (1). The other end of the pop-up rod is provided with a ring, which bulges upward in the middle. The ring is fixed inside the housing. A spring is provided between the ring and the top of the housing. The pop-up rod passes through the spring; A firing device, which includes an injection rod housing, an injection rod, and an injection spring groove (2). The pop-up rod extends into the injection rod. At the upper port of the injection rod, there is a display board that extends parallel to the surroundings. The display board abuts against the lower end of the ring. An injection rod spring is provided inside the injection rod. The bottom end of the pop-up rod is inside the injection rod spring and has no contact with the injection rod spring. Two opposite outwardly protruding injection spring grooves are provided on the outside of the injection rod. An extrusion spring is fixedly connected inside the injection spring groove. The other end of the extrusion spring is fixedly connected to one end of a rocker spring. The fulcrum of the rocker spring fits against the outer wall of the injection rod. One end of the rocker spring connecting the spring abuts against the top of the convex block inside the injection rod housing. The other end of the rocker spring abuts against the display board extending outward at the top of the injection rod. A downwardly protruding push rod is also provided at the bottom of the injection rod; A drug storage device, which includes a cartridge and a cartridge housing. A piston is provided inside the cartridge. The bottom of the cartridge is connected to a needle, and the needle is replaceable. The cartridge is arranged inside the cartridge housing. The injection push rod abuts against the upper end of the piston, and the piston is arranged inside the upper end of the cartridge; The lower end of the firing device is threadedly connected to the drug storage device, and the safety device is snap-connected to the upper end of the firing device; When in use, when the housing is rotated clockwise by 90°, the safety device is in the unlocked state. One of the buckles is at the fan-shaped card slot at the end with the groove. At this time, the spring drives the housing to pop up upward until the bottom end of the pop-up rod is stuck at the position of the ring. One end of the needle is placed on the skin surface. Press the top cover to make the needle penetrate the skin, and at the same time drive the housing to move downward. The lower end of the housing squeezes the lower part of the rocker spring, so that the spring squeezed by the lower end of the rocker spring is compressed inward. When the bottom end of the rocker spring leaves the convex block inside the injection rod housing, the injection rod spring inside the injection rod pops out, and the ejection force is used to push the push rod at the lower end of the injection rod to push the piston at the upper part of the cartridge arranged inside the cartridge housing, pressing the piston to move downward, and injecting the liquid medicine into the subcutaneous tissue.

2. A pre-filled automatic syringe with replaceable drug according to claim 1, characterized in that, The needle adopts a hollow microneedle array structure.

3. A pre-filled automatic syringe with replaceable drug according to claim 1, characterized in that, A medicine viewing window is provided on the side of the drug storage device for observing the remaining amount of the drug in the drug storage device.

4. A pre-filled auto-injector for replaceable drugs according to claim 1 or claim 3, characterized in that, the drug storage device uses multiple colors, and different drugs are loaded according to different colors.

5. A pre-filled auto-injector for replaceable drugs according to claim 2, characterized in that, the needles are circularly distributed with 4-8 needles on a circle with a diameter of 1 cm.

6. A pre-filled auto-injector for replaceable drugs according to claim 2 or claim 5, characterized in that, the length of the needles is 0.2 mm - 4 mm.

7. A pre-filled auto-injector for replaceable drugs according to claim 2 or claim 5, characterized in that, the thickness of the needles is 27G - 34G.

8. A pre-filled auto-injector for replaceable drugs according to any one of claims 1-3, characterized in that, the drug storage device is provided with a micro-needle protective cover, and the micro-needle protective cover is snap-connected to the drug storage device.

9. A pre-filled auto-injector for replaceable drugs according to claim 8, characterized in that, a silica gel pad is provided inside the micro-needle protective cover.

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