A blood sample automatic mixing device and blood cell analysis equipment
By designing an automatic mixing device for blood samples including rotary swing and vibration, the problem that the prior art cannot effectively mix trace blood samples automatically is solved, and efficient automatic mixing operation is achieved, saving manpower and time costs, and miniaturization of blood cell analysis equipment is promoted.
Patent Information
- Application Number
- CN201910324795.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2018-04-24
- Filing Date
- 2019-04-22
- Publication Date
- 2025-05-09
- Estimated Expiration
- 2039-04-22
AI Technical Summary
Existing blood cell analyzers cannot effectively and automatically mix trace amounts of peripheral blood samples, resulting in low working efficiency and inconvenient sample mixing and operating.
An automatic mixing device for blood samples is designed, including a first bracket, a second bracket and a flexible column. The second bracket is fixed above the first bracket through a flexible column connection, and can swing and vibrating with respect to the first bracket, and drive the test tube to perform corresponding movement to achieve automatic mixing.
It realizes automatic and sufficient mixing of trace blood samples without manual processing, saving labor and time costs, and improving the working efficiency of trace blood samples. The device is simple and compact, which is conducive to the miniaturization of the instrument.
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Figure CN110398594B_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of blood cell analysis, and more specifically, relates to an automatic blood sample mixing device and a blood cell analysis device. Background Art
[0002] At present, there are two blood collection methods for routine blood tests: collecting venous blood and collecting peripheral blood. Among them, the venous blood collection volume is large, at the milliliter (ml) level, suitable for patients such as adults who are convenient for blood collection; while the peripheral blood collection volume is small, around 100 microliters (ul), suitable for patients such as children who are inconvenient for blood collection. Since the sample volume of peripheral blood is too small compared to the sample volume of venous blood, the two are not of the same order of magnitude. At present, the model with a mechanical automatic mixing device on the blood cell analyzer mainly simulates the manual test tube back and forth mixing method, or swings and rotates, that is, swings around the central axis of the test tube or a point on its extension line. However, the above-mentioned mechanical automatic mixing method is only applicable to the mixing of venous blood samples, and cannot meet the requirements of routine blood tests for the mixing of trace peripheral blood samples in the test tube, and is not applicable to the mixing of peripheral blood samples in the test tube. When analyzing and testing peripheral blood samples, most of them use manual shaking of the peripheral blood test tube for mixing, which has low work efficiency and inconvenient sample mixing operation.
[0003] Therefore, it is necessary to propose an automatic mixing device suitable for mixing trace blood samples. Summary of the invention
[0004] The present invention aims to solve the problems existing in the above-mentioned prior art to a certain extent, and provides a blood sample automatic mixing device and method, so as to automatically and fully mix trace blood samples without manual processing, saving manpower and time costs, and improving the work efficiency of mixing trace blood samples.
[0005] To this end, an embodiment of the present invention provides an automatic blood sample mixing device, which includes a first bracket, a second bracket and a flexible column. The second bracket is connected and fixed above the first bracket through the flexible column, and can rotate and vibrate relative to the first bracket. The part of the flexible column located between the first bracket and the second bracket is arranged in an hourglass shape.
[0006] In one embodiment, the automatic blood sample mixing device also includes a first driving unit and an eccentric block. The first driving unit is arranged on the second bracket. The eccentric block is fixed on the output shaft end of the first driving unit. When driven by the first driving unit, the eccentric block rotates around the axis of the first driving unit, thereby driving the second bracket to perform rotational swing and vibration relative to the first bracket, thereby driving the test tube supported and fixed to the second bracket to perform rotational swing and vibration synchronously.
[0007] In one embodiment, the automatic blood sample mixing device further comprises a third support and a test tube compartment, the first support and the third support are connected via a support rod, and the test tube compartment is disposed on the third support.
[0008] In one embodiment, a test tube tray is disposed on the second support, and the test tube tray is provided with a concave curved surface, and the concave curved surface is used to abut against the bottom of the test tube to accommodate the test tube in the test tube warehouse.
[0009] In one embodiment, a first hollow groove and a second hollow groove are provided on the second bracket, a portion of the support rod is passed through the first hollow groove, and the flexible module is a flexible column, a portion of the flexible column is located in the second hollow groove.
[0010] In one embodiment, a third hollow groove is opened on the side portion of the second bracket, and the third hollow groove is an arc-shaped structure with one side open; the number of the support rods is two, a portion of one support rod is arranged in the first hollow groove, and a portion of the other support rod is arranged in the third hollow groove.
[0011] In one embodiment, the test tube warehouse includes a hollow sleeve, which is arranged on the top of the third bracket. The third bracket has a through hole at a position corresponding to the hollow sleeve, and the hollow sleeve and the through hole are used to accommodate the test tube to constrain the movable position of the test tube.
[0012] In one embodiment, the flexible column is made of rubber or silicone material, or is a spring.
[0013] In one embodiment, a concave platform is provided on the side of the second bracket, and the second hollow groove is provided on the concave platform. The flexible column includes an upper column head and a column body, the upper column head is provided on the surface of the concave platform, and the column body is provided in the second hollow groove.
[0014] In one embodiment, the cross-section of the upper column cap is a circular structure, the column body is a cylindrical structure, the diameter of the circular cross-section of the upper column cap is larger than the diameter of the cylindrical structure of the column body, the flexible column includes a lower column cap, a connecting head is provided under the lower column cap, a connecting hole is provided on the first bracket, and the connecting head is passed through the connecting hole to fix the flexible column on the first bracket.
[0015] Compared with the prior art, the implementation of the automatic blood sample mixing device of the present invention has the following beneficial effects: under the drive of the first driving unit, the eccentric block fixed on the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module to which the first driving unit is fixed is connected and fixed above the first bracket through a flexible module, and the rotating shaft hole of the eccentric block is not on its center of gravity, the eccentric block drives the vibration module to swing and vibrate in a rotational manner when it rotates. Since the blood sample collection tube containing the sample to be mixed is arranged on the test tube tray of the second bracket, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate in a rotational manner, so as to achieve the purpose of automatically mixing the sample, without manual processing, saving manpower and time costs, and improving the working efficiency of mixing trace blood samples. In addition, the automatic blood sample mixing device provided by the present invention has a relatively simple and compact structure, which is conducive to the miniaturization of the instrument.
[0016] As the same inventive concept, according to the second aspect, an embodiment of the present invention also provides a blood cell analysis device, which includes the aforementioned automatic blood sample mixing device, the blood cell analysis device also includes an automatic feeding device, the automatic feeding device includes a base and a transmission assembly, a second driving unit is fixed on the base, the transmission assembly is movably arranged on the base, the transmission assembly is connected to the first bracket, the second driving unit drives the transmission assembly to move relative to the base, and the transmission assembly drives the first bracket to move to move the test tube compartment to a preparation position for receiving a blood sample collection tube.
[0017] In one embodiment, the transmission assembly includes a sliding block, a sliding guide rail, a fixed block, a movable push plate and a sliding screw nut mechanism, the sliding guide rail is fixed on the base, and the slider is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second driving unit and the movable push plate; the fixed block is respectively connected to the first bracket and the slider; the movable push plate pushes the fixed block and the slider to move under the action of the sliding screw nut mechanism, and the slider moves along the sliding guide rail to guide the moving direction of the fixed block.
[0018] In one embodiment, a shielding optical coupling baffle is fixed on the movable push plate, and a detection optical coupler is provided on the base. The detection optical coupler and the shielding optical coupling baffle cooperate to detect the moving position of the movable push plate.
[0019] In one embodiment, the blood cell analysis equipment also includes a test tube clamp, which is used to first perform a descending action together with the grasped trace peripheral blood collection test tube, and the descending height is that the bottom of the test tube touches or approaches the rubber test tube support with a concave surface fixed on the second horizontal bracket, and then the test tube clamp performs horizontal feeding and moves away from the test tube rack to a horizontal ready position, so that the test tube clamp is completely separated from the clamped test tube.
[0020] Compared with the prior art, the blood cell analysis device of the present invention has the following beneficial effects:
[0021] The present invention discloses a blood cell analysis device, which includes an automatic feeding device and a blood sample automatic mixing device. First, the automatic feeding device includes a base and a transmission component, and the second driving unit drives the transmission component to move, and the movement of the transmission component is used to drive the first bracket to move. Since the test tube warehouse is arranged on the third bracket, the test tube warehouse can be moved to a preparation position for receiving the blood sample collection test tube, so as to realize the automatic feeding of the blood sample collection tube. Secondly, under the drive of the first driving unit, the eccentric block fixed on the output shaft end of the first driving unit rotates around the first driving unit axis. Since the vibration module for fixing the first driving unit is connected and fixed above the first bracket through a flexible module, and the rotating shaft hole of the eccentric block is not on its center of gravity, the eccentric block drives the vibration module to swing and vibrate in a rotary manner when rotating. Since the blood sample collection test tube containing the sample to be mixed is arranged on the test tube tray of the first bracket, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to realize the purpose of automatically mixing the sample, without manual processing, saving manpower and time costs, and improving the working efficiency of mixing trace blood samples.
[0022] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, preferred embodiments are specifically listed below and described in detail with reference to the attached drawings. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.
[0024] Figure 1 This is a schematic diagram of the structure of the automatic blood sample mixing device according to an embodiment of the present invention;
[0025] Figure 2 This is a schematic diagram of the test tube bin according to an embodiment of the present invention moving to a preparation position for receiving test tubes to be mixed.
[0026] In the figure, a first bracket 1, a second bracket 2, a third bracket 3, an eccentric block 4, a shock-absorbing column 5, a first motor 6, a test tube tray 7, a first hollow groove 8, a second hollow groove 9, a test tube compartment 10, a support rod 11, a recessed table 12, an upper column head 13, a column 14, a third hollow groove 15, a test tube 16, a base 17, a second motor 18, a sliding block 19, a sliding guide rail 20, a fixed block 21, a movable push plate 22, a sliding screw nut mechanism 23, a shielding optical coupler baffle 24, a detection optical coupler 25, and a test tube clamp 26. DETAILED DESCRIPTION
[0027] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. The components of the embodiments of the present invention generally described and shown in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents the selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making creative work belong to the scope of protection of the present invention.
[0028] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.
[0029] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0030] like Figure 1As shown, an embodiment of the present invention provides an automatic blood sample mixing device, which can be used for mixing trace blood samples, such as mixing peripheral blood samples. Specifically, the automatic blood sample mixing device includes a main body and a vibration module. The main body is provided with a test tube compartment. The vibration module includes a first driving unit, an eccentric block and a test tube support module. The first driving unit, the eccentric block and the test tube support module are connected in sequence. The test tube support module is used to support the bottom of the blood sample collection tube so that the blood sample collection tube can be accommodated in the test tube compartment. The first driving unit drives the eccentric block to rotate and drives the test tube support module and the bottom of the blood sample collection tube to make a swinging motion to mix the blood sample in the blood sample collection tube. According to the above description, and Figure 1 According to the records, it can be known that the eccentric block, the main body, and the vibration module are linked with the blood sample collection tube contained in the test tube compartment. The eccentric block is driven by the first driving unit to perform eccentric movement, which can drive the bottom of the blood sample collection tube in the test tube compartment to move. The upper part of the blood sample collection tube is located in the test tube compartment and can move in the test tube compartment, thereby realizing automatic mixing of the sample in the test tube.
[0031] In the automatic blood sample mixing device of the embodiment of the present invention, under the drive of the first driving unit, the eccentric block fixed on the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module that fixes the first driving unit is connected and fixed above the main body, and the rotating shaft hole of the eccentric block is not on its center of gravity, the eccentric block drives the vibration module to swing and vibrate rotationally when it rotates. Since the blood sample collection tube containing the sample to be mixed is arranged on the test tube tray of the main body, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate rotationally, so as to achieve the purpose of automatically mixing the sample, without manual processing, saving manpower and time costs, and improving the work efficiency of mixing trace blood samples.
[0032] Furthermore, in a certain embodiment, the vibration module further includes a flexible module, one end of the flexible module is arranged on the test tube supporting module, and the other end of the flexible module is fixed on the body.
[0033] In the embodiment of the present invention, the flexible module is made of a flexible material, and the flexible module is provided to enable the test tube support module to perform a better rotational swing, thereby driving the blood sample collection test tube to swing and achieve sufficient mixing.
[0034] In a certain embodiment, the body includes a first bracket and a third bracket, the test tube support module includes a second bracket, the first bracket and the third bracket are connected by a support rod; so that the third bracket is fixed to the first bracket; the eccentric block is arranged on the first bracket, and the first driving unit is arranged on the second bracket; one end of the flexible module is connected to the first bracket, and the other end is connected to the second bracket; the test tube compartment is arranged on the third bracket. Preferably, the second bracket is located between the first bracket and the third bracket.
[0035] In an embodiment of the present invention, the first bracket can perform eccentric motion around the motor shaft under the action of the eccentric block and the first driving unit, and then drive the second bracket to perform rotational swing relative to the first bracket and the third bracket through the flexible module. At this time, since the test tube support is fixed on the second bracket, the second bracket will drive the test tube to perform rotational swing synchronously when performing rotational swing, so as to achieve sufficient mixing of the blood sample in the test tube.
[0036] In a certain embodiment, a test tube tray is disposed on the second support, and the test tube tray is provided with a concave curved surface, and the concave curved surface is used to support the bottom of the test tube to accommodate the test tube in the test tube compartment.
[0037] In this embodiment, the concave curved surface forms a cavity, and a part of the bottom of the test tube containing the sample to be mixed is arranged in the cavity, so that the test tube is supported, and the test tube tray and the test tube warehouse cooperate to fix the test tube of the sample to be mixed on the automatic blood sample mixing device. During the mixing operation, the test tube tray drives the bottom of the test tube to swing and vibrate in a rotational manner to achieve sufficient mixing of the blood sample in the test tube.
[0038] In one embodiment, the second bracket is provided with a first hollow groove and a second hollow groove, a part of the support rod is inserted into the first hollow groove, the flexible module is a flexible column, a part of the flexible column is located in the second hollow groove. The first hollow groove should have enough space to allow the support rod to move in the first hollow groove; a part of the flexible column is located in the second hollow groove, and the output shaft of the first drive unit is connected to the eccentric block.
[0039] In this embodiment, according to the above description, and Figure 1 According to the records, the eccentric block, the flexible module, the second bracket and the test tube tray are linked with the test tubes contained in the test tube bin. The eccentric block rotates around the axis of the first driving unit to make an eccentric motion and at the same time can drive the test tubes in the test tube bin to make a rotary swing to realize automatic mixing of the samples in the test tubes.
[0040] Specifically, in this embodiment, when mixing blood samples, the test tube containing the blood sample to be mixed is placed in the test tube bin, and the bottom of the test tube is supported by the test tube tray, so the test tube will be confined in the test tube bin, and the test tube bin should have enough space so that the test tube can move in the test tube bin when the mixing operation is performed. Driven by the first drive unit, the eccentric block fixed on the output shaft end of the first drive unit rotates around the first drive unit axis. Since the second bracket for fixing the first drive unit is fixed above the first bracket through a flexible column connection, and the rotating shaft hole of the eccentric block is not on its center of gravity, the rotation of the eccentric block drives the second bracket to swing and vibrate in a rotary manner. Since the test tube containing the sample to be mixed is set on the test tube tray of the second bracket, the swing and vibration of the second bracket will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to achieve the purpose of automatically mixing the sample, without manual processing, saving manpower and time costs, and improving the work efficiency of mixing trace blood samples.
[0041] Preferably, the first drive unit is preferably but not limited to a DC brushless motor, which is driven and controlled by a controller. It should be noted that, based on technical experience, the first drive unit can also be selected as other mechanisms that can provide driving force. The specific selection of the first drive unit is not exhaustively listed in the embodiment of the present invention.
[0042] Preferably, the test tube tray is preferably but not limited to being made of flexible materials such as rubber or silicone. The DC brushless motor is driven for a certain period of time, and the eccentric block rotates around the motor shaft, thereby driving the second horizontal bracket to produce rotational swing and vibration; the bottom of the micro-peripheral blood collection test tube that falls on the rubber test tube tray with a concave surface fixed on the second horizontal bracket produces rotational swing and vibration along with the second horizontal bracket, and the test tube bin is relatively still to constrain the body of the micro-peripheral blood collection test tube, and the bottom of the micro-peripheral blood collection test tube swings relatively large; thereby, the blood sample in the micro-peripheral blood collection test tube is mixed under the combination of centrifugal shaking and vibration, while preventing blood cells from being broken.
[0043] In one embodiment, the first hollow groove is circular, a portion of the support rod passing through the first hollow groove is a cylinder, and the diameter of the circular first hollow groove is greater than the diameter of the cylinder. When the eccentric block in the embodiment of the present invention rotates, it drives the second bracket to swing and vibrate in a rotary manner. The design of the cylinder and the circular first hollow groove enables the second bracket to swing and vibrate in a rotary manner relative to the third bracket, further driving the test tube to swing and vibrate in a rotary manner.
[0044] In one embodiment, a concave platform is provided on the side of the second bracket, and the second hollow groove is provided on the concave platform; the flexible column includes an upper column head and a column body, the upper column head is provided on the surface of the concave platform, and the column body is provided in the second hollow groove. The cross-sections of the upper column head and the second hollow groove of the flexible body are both circular structures, the column body is a cylindrical structure, the diameter of the circular cross-section of the upper column head of the flexible body is larger than the diameter of the cylindrical structure and the diameter of the circular cross-section of the second hollow groove, and the flexible body is made of a flexible material, such as rubber or silicone material, or a spring, so that the second bracket can swing relative to the third bracket and the first bracket.
[0045] In one embodiment, the flexible column includes a lower column head, a connecting head is arranged below the lower column head, a connecting hole is arranged on the first bracket, and the connecting head is inserted into the connecting hole to fix the flexible column on the first bracket. The lower column head of the flexible body is a circular structure, and the diameter of the circular structure cross section of the lower column head of the flexible body is larger than the diameter of the cylindrical structure and the diameter of the circular structure cross section of the second hollow groove.
[0046] In one embodiment, a third hollow groove is opened on the side portion of the second bracket, and the third hollow groove is an arc-shaped structure with one side open; the number of the support rods is two, a part of one support rod is arranged in the first hollow groove, and a part of the other support rod is arranged in the third hollow groove, wherein a part of the other support rod is a cylindrical structure, so that the second bracket can perform rotational swing and vibration relative to the third bracket and the first bracket.
[0047] In one embodiment, the test tube warehouse includes a hollow sleeve, the hollow sleeve is arranged on the top of the third bracket, the third bracket is provided with a through hole, the hollow sleeve and the through hole are coaxially arranged, and the through portion of the hollow sleeve and the through hole forms a test tube accommodating space. When the embodiment of the present invention is implemented, the test tube tray holds the test tube, and the test tube accommodating space is used to accommodate the test tube to constrain the active position of the test tube, so as to fix the test tube and allow the test tube to perform rotational swing.
[0048] According to the second aspect, another embodiment of the present invention provides a blood cell analysis device, which includes the aforementioned automatic blood sample mixing device, the blood cell analysis device also includes an automatic feeding device, the automatic feeding device includes a base and a transmission assembly, a second driving unit is fixed on the base, the transmission assembly is movably arranged on the base, the transmission assembly is connected to the main body, the second driving unit drives the transmission assembly to move relative to the base, and the transmission assembly drives the main body to move to move the test tube compartment to a preparation position for receiving a blood sample collection tube.
[0049] A blood cell analysis device according to an embodiment of the present invention comprises an automatic feeding device and a blood sample automatic mixing device. First, the automatic feeding device comprises a base and a transmission assembly, and the second driving unit drives the transmission assembly to move, and the movement of the transmission assembly is used to drive the body to move. Since the test tube bin is arranged on the body, the test tube bin can be moved to a preparation position for receiving the blood sample collection tube, so as to realize the automatic feeding of the blood sample collection tube. Secondly, under the drive of the first driving unit, the eccentric block fixed on the output shaft end of the first driving unit rotates around the first driving unit axis. Since the vibration module for fixing the first driving unit is connected and fixed on the top of the body through the flexible module, and the rotating shaft hole of the eccentric block is not on its center of gravity, the eccentric block drives the vibration module to swing and vibrate in a rotary manner when rotating. Since the blood sample collection tube containing the sample to be mixed is arranged on the test tube tray of the body, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to realize the purpose of automatically mixing the sample, without manual processing, saving manpower and time costs, and improving the working efficiency of mixing trace blood samples.
[0050] Furthermore, the second driving unit is preferably a motor. In one embodiment, the device further comprises a base and a transmission assembly, the base is fixed with a second motor, the second motor is electrically connected to the controller and is controlled by the controller, the transmission assembly is movably arranged on the base, the transmission assembly is connected to the first bracket, the second motor drives the transmission assembly to move relative to the base, the transmission assembly drives the first bracket and the third bracket to move so as to move the test tube bin to a preparation position for receiving the test tube to be mixed, the preparation position is as follows: Figure 2 shown.
[0051] In one embodiment, the transmission assembly includes a sliding block, a sliding guide rail, a fixed block, a movable push plate and a sliding screw nut mechanism. The sliding guide rail is fixed on the base, and the slider is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second motor and the movable push plate; the fixed block is respectively fixedly connected to the first bracket of the body and the slider; the sliding guide rail is passed through the opening in the middle of the movable push plate, and the movable push plate abuts the fixed block, and the movable push plate can be fixedly connected to the fixed block or not fixedly connected, and the movable push plate pushes the fixed block and the slider to move under the action of the sliding screw nut mechanism, and the slider moves along the sliding guide rail to guide the moving direction of the fixed block, and the slider and the sliding guide rail play a guiding role here so that the mixing device can be fed to the target position. Among them, the sliding screw nut mechanism is a propulsion mechanism well known to those skilled in the art, so its specific structure is not explained here.
[0052] In one embodiment, a blocking optical coupling baffle is fixed on the moving push plate, and a detection optical coupling is provided on the base, and the detection optical coupling and the blocking optical coupling baffle cooperate to detect the moving position of the moving push plate. Specifically, when the moving push plate is advanced, the blocking optical coupling baffle is also advanced accordingly, and when the light emitted by the detection optical coupling is blocked by the blocking optical coupling baffle, it is determined that the moving push plate has been advanced to the target position, and at this time, the controller controls the second motor to stop rotating, and the moving push plate stops advancing.
[0053] Preferably, the second motor is a linear motor, and the movement and feeding of the automatic blood sample mixing device adopts a horizontal feeding method. Specifically, in the embodiment of the present invention, the automatic blood sample mixing device is in its ready position, and first executes the horizontal feeding linear motor drive, and the sliding screw nut mechanism of the linear motor drives the moving push plate, the optical coupling baffle and the fixed block to feed horizontally to the appropriate position in the direction of the test tube rack, and feeds synchronously with all the related components and parts installed on the fixed block, including the first bracket, the second bracket and the third bracket and the parts installed thereon; the appropriate feeding position is the coaxial center of the test tube bin fixed on the third horizontal bracket and the center of the lifted test tube, such as Figure 2 As shown. The test tube clamp, together with the grasped micro-peripheral blood collection test tube, first performs a descending action, and the descending height is such that the bottom of the test tube touches or approaches the rubber test tube holder with a concave surface fixed on the second horizontal bracket; then the test tube clamp performs horizontal feeding and moves away from the test tube rack to the horizontal ready position, so that the test tube clamp is completely separated from the clamped test tube. At this point, the preparation for the blood sample mixing operation is completed, and the specific mixing operation as described above can be performed immediately. For details, please refer to the previous part, which will not be described in detail here.
[0054] With reference to the specific embodiments, although the present invention has been described in the specification and the drawings, it should be understood that, without departing from the scope of the invention defined in the claims, the technical personnel of the relevant technical field can make various changes and various equivalents can replace various elements therein. Moreover, the combination and matching of the technical features, elements and / or functions between the specific embodiments herein are clear and distinct, so according to these disclosed contents, the technical personnel of the relevant technical field can appreciate that the technical features, elements and / or functions in the embodiments can be combined into another specific embodiment as appropriate, unless the above contents are otherwise described. In addition, according to the teachings of the present invention, many changes can be made to adapt to special circumstances or materials without departing from the scope of the essence of the present invention. Therefore, the present invention is not limited to the individual specific embodiments illustrated in the drawings, and the specific embodiments described in the specification as the best embodiments currently envisioned for implementing the present invention, and the present invention is intended to include all embodiments falling within the scope of the above description and the attached claims.
Claims
1. A blood sample automatic mixing device, characterized in that: The blood sample automatic mixing device comprises a first bracket, a second bracket, a third bracket, a flexible column, a test tube compartment, a first driving unit and an eccentric block, wherein the first driving unit is arranged on the second bracket, the eccentric block is fixed on the output shaft end of the first driving unit, and the eccentric block is driven by the first driving unit to rotate around the axis of the first driving unit, thereby driving the second bracket to perform rotary swing and vibration relative to the first bracket, thereby driving the test tube supported and fixed to the second bracket to perform rotary swing and vibration synchronously, and the second bracket is connected and fixed above the first bracket through the flexible column, and can perform rotary swing and vibration relative to the first bracket; Among them, the first bracket and the third bracket are connected by a support rod, the test tube warehouse is arranged on the third bracket, and the test tube warehouse is used to make the upper part of the test tube be located in the test tube warehouse so that the test tube can be accommodated in the test tube warehouse; a first hollow groove is arranged on the second bracket, a part of the support rod is passed through the first hollow groove, and the first hollow groove has enough space to enable the support rod to move in the first hollow groove.
2. The blood sample automatic mixing device according to claim 1, characterized in that: A test tube tray is arranged on the second bracket. The test tube tray is provided with a concave curved surface. The concave curved surface is used to abut the bottom of the test tube to accommodate the test tube in the test tube bin.
3. The blood sample automatic mixing device according to claim 1, characterized in that: A second hollow groove is provided on the second bracket, and a part of the flexible column is located in the second hollow groove; The first driving unit includes a brushless DC motor.
4. The blood sample automatic mixing device according to claim 3, characterized in that: A third hollow groove is opened on the side portion of the second bracket, and the third hollow groove is an arc-shaped structure with one side open; there are two support rods, a part of one support rod is arranged in the first hollow groove, and a part of the other support rod is arranged in the third hollow groove.
5. The blood sample automatic mixing device according to claim 4, characterized in that: The test tube warehouse includes a hollow sleeve, which is arranged on the top of the third bracket. The third bracket has a through hole at a position corresponding to the hollow sleeve. The hollow sleeve and the through hole are used to accommodate the test tube to constrain the active position of the test tube.
6. The blood sample automatic mixing device according to claim 1, characterized in that: The flexible column is made of rubber or silicone material, or is a spring.
7. The blood sample automatic mixing device according to claim 3, characterized in that: A concave platform is provided on the side of the second bracket, and the second hollow groove is provided on the concave platform. The flexible column includes an upper column head and a column body. The upper column head is provided on the surface of the concave platform, and the column body is provided in the second hollow groove. The cross-section of the upper column head is a circular structure, and the column body is a cylindrical structure. The diameter of the circular structure cross-section of the upper column head is greater than the diameter of the cylindrical structure of the column body.
8. The blood sample automatic mixing device according to claim 1, characterized in that: The flexible column includes a lower column head, a connecting head is arranged below the lower column head, a connecting hole is arranged on the first bracket, and the connecting head is inserted into the connecting hole to fix the flexible column on the first bracket.
9. A blood cell analysis device, comprising the blood sample automatic mixing device according to any one of claims 1 to 8, characterized in that: The blood cell analysis equipment also includes an automatic feeding device, which includes a base and a transmission assembly. A second driving unit is fixed on the base, and the transmission assembly is movably arranged on the base. The transmission assembly is connected to the first bracket, and the second driving unit drives the transmission assembly to move relative to the base. The transmission assembly drives the first bracket to move to move the test tube bin to a preparation position for receiving a blood sample collection tube to be mixed.
10. The blood cell analysis device according to claim 9, characterized in that: The transmission assembly includes a sliding block, a sliding guide rail, a fixed block, a movable push plate and a sliding screw nut mechanism. The sliding guide rail is fixed on the base, and the sliding block is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second driving unit and the movable push plate; the fixed block is respectively connected to the first bracket and the sliding block, and the movable push plate pushes the fixed block and the sliding block to move under the action of the sliding screw nut mechanism, and the sliding block moves along the sliding guide rail to guide the moving direction of the fixed block.
11. A blood cell analysis device according to claim 10, characterized in that: A shielding optical coupling baffle is fixed on the movable push plate, and a detection optical coupler is arranged on the base. The detection optical coupler and the shielding optical coupling baffle cooperate to detect the moving position of the movable push plate.
12. The blood cell analysis device according to claim 9, characterized in that: The blood cell analysis equipment also includes a test tube clamp, which is used to first perform a descending action together with the grasped micro-extremity blood sample collection test tube, and the descending height is that the bottom of the blood sample collection test tube touches or approaches the rubber test tube tray with a concave surface fixed on the second bracket, and then the test tube clamp performs horizontal feeding and moves in a direction away from the test tube rack to a horizontal ready position, so that the test tube clamp is completely separated from the clamped blood sample collection test tube.
Citation Information
Patent Citations
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