Multifunctional intrauterine adhesion prevention and treatment device

Abstract

The present invention discloses a multifunctional intrauterine adhesion prevention and treatment device, which includes a diaphragm, a detachable buckle, a uterine-shaped silicone ring, a drug release balloon, a connecting tube and a one-way valve for drug injection; wherein, the diaphragm is provided with a placement rod connection bayonet and a mounting hole, the drug release balloon is provided with a drug release hole, and the one-way valve for drug injection is provided with two semicircular silicone sheets supporting each other. The present invention allows the drug to act more directly on the corresponding part, prolongs the drug action time, reduces the risk of infection, effectively prevents intrauterine adhesion, and reduces multiple intrauterine operations after intrauterine adhesion; and can be placed for a long time, which helps to improve the effectiveness of intrauterine adhesion treatment for patients and reduce the recurrence of intrauterine adhesion; at the same time, the patient's treatment can be carried out in multiple ways at the same time, providing a carrier for the development of intrauterine adhesion biological treatment; the placement process and placement device of the present invention are common to the existing intrauterine contraceptive device placement rod, and the placement method is similar, which increases the convenience of using the device.

Description

Technical Field

[0001] The present invention belongs to the field of medical devices, and in particular relates to a multifunctional device for preventing and treating intrauterine adhesions. Background Art

[0002] Although there are currently a variety of devices or tissues used clinically to prevent and treat intrauterine adhesions, there is no dedicated device for the prevention and treatment of patients with intrauterine adhesions. Most of them use intrauterine devices or balloon devices for intrauterine hemostasis. The intrauterine devices currently used on the market are mostly copper-containing devices, which are not conducive to the repair of the endometrium. The intrauterine balloon used for hemostasis may cause mechanical damage to the endometrium due to the need to inject liquid to expand the balloon, and it cannot be left in place for a long time. At the same time, neither intrauterine devices nor intrauterine balloons are well suited for different types and degrees of intrauterine adhesions, and intrauterine drug treatment is not possible. At the same time, these two types of devices are not suitable for the prevention and treatment of adhesions in patients with different degrees of adhesions or different degrees of endometrial damage. At present, the commonly used method for severe intrauterine adhesions is to place a balloon uterine stent to physically block endometrial adhesions, and perform artificial cycle (estrogen-progesterone) treatment for repair and regeneration. At the same time, the balloon uterine stent needs to be removed one week after surgery, and intrauterine drug treatment can be performed after surgery to promote endometrial repair. If necessary, it can be replaced with an intrauterine contraceptive device. For the above treatment options, there is a need to remove the balloon device one week after surgery, and there may be multiple intrauterine operations during this period, which has a high risk of infection and injury. For moderate intrauterine adhesions, ordinary intrauterine contraceptive devices are placed and artificial cycles are taken for treatment. For this treatment option, the intrauterine contraceptive device is a physical edge blocker, and the prevention and treatment effect on central intrauterine adhesions is poor. For patients with severe intrauterine adhesions, combined intrauterine drug treatment or amniotic membrane or stem cell scaffolds are often required. The current intrauterine adhesion prevention and treatment device does not have a drug carrying device, and intrauterine drug treatment cannot be performed, and the effect of simply placing an intrauterine contraceptive device is poor. Summary of the Invention

[0003] The purpose of the present invention is to address the deficiencies of the existing technology and provide a multifunctional intrauterine adhesion prevention and treatment device. The present invention is suitable for the prevention and treatment of patients with different types and degrees of intrauterine adhesions, and can be used as an auxiliary treatment using drugs, biological agents and nanomaterials.

[0004] The objective of the present invention is achieved through the following technical solutions: a multifunctional intrauterine adhesion prevention and treatment device, comprising a main body, a connecting tube and a one-way valve for drug injection; wherein the main body is composed of a diaphragm, a uterine-shaped silicone ring and a drug-releasing balloon; the drug-releasing balloon is connected to the connecting tube, and the drug-releasing balloon is provided with a drug-releasing hole; the uterine-shaped silicone ring is fixedly connected to one end of the connecting tube, and a diaphragm is arranged in the area between the uterine-shaped silicone ring, the connecting tube and the drug-releasing balloon; a rod connection socket and an installation hole are provided on the diaphragm; the one-way valve for drug injection is connected to the other end of the connecting tube; and two semicircular silicone sheets supporting each other are arranged inside the one-way valve for drug injection.

[0005] Furthermore, it also includes a detachable buckle, which is a columnar structure with an I-shaped cross-section, and the detachable buckle is clamped in the installation hole.

[0006] Furthermore, the detachable buckle has a through hole along the axial direction.

[0007] Furthermore, the drug-releasing balloon is a flat balloon.

[0008] Furthermore, the drug-releasing balloon has four drug-releasing holes on each of the front and rear surfaces, arranged in a square array.

[0009] Furthermore, the diaphragm is a silicone membrane.

[0010] Furthermore, the placement rod connection bayonet is a crescent-shaped hollow.

[0011] Furthermore, a depth mark is provided on the connecting tube for calibrating the depth of the main body in the uterine cavity.

[0012] The beneficial effects of the present invention are as follows: a multifunctional intrauterine adhesion prevention and treatment device of the present invention can benefit patients with different degrees and types of intrauterine adhesions, and can further assist in adding drug treatment according to the needs of the disease, so that the drug can act on the corresponding part more directly, prolong the time of drug action, reduce the risk of infection, effectively prevent intrauterine adhesions, and reduce multiple intrauterine operations after intrauterine adhesions; and it can be placed for a long time, which helps to improve the effectiveness of the patient's intrauterine adhesion treatment and reduce the recurrence of intrauterine adhesions. At the same time, the patient's treatment can be carried out in multiple ways at the same time, providing a carrier for the development of biological treatment of intrauterine adhesions (such as stem cell treatment); new drug research for intrauterine adhesions is carried out through the device of the present invention, making the treatment of intrauterine adhesions diverse and effective; the placement process and placement device of the device of the present invention are universal with the existing intrauterine device placement rod, and the placement method is similar, which increases the convenience of using the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] The present invention will be further described below with reference to the accompanying drawings and embodiments:

[0014] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0015] Figure 2 It is a three-dimensional modeling and front view of the intrauterine part of the present invention;

[0016] Figure 3 It is a three-dimensional modeling and cross-sectional diagram of the detachable drug storage buckle;

[0017] Figure 4 It is the three-dimensional modeling and cross-sectional drawing of the one-way valve at the end of the connecting pipe;

[0018] Figure 5 It is a three-dimensional modeling diagram of the placement of the rod;

[0019] In the figure: main body 1, connecting tube 2, one-way valve for drug injection 3, depth mark 4, placement rod connecting bayonet 5, diaphragm 6, uterine-shaped silicone ring 7, drug release balloon 8, mounting hole 9, detachable buckle 10, semicircular silicone sheet 11, placement rod slot 12. DETAILED DESCRIPTION

[0020] The multifunctional intrauterine adhesion prevention and treatment device of the present invention is as follows Figure 1 As shown, the device comprises a main body 1, a connecting tube 2, and a one-way valve 3 for drug injection. Connecting tube 2 is provided with depth markings 4, which are used to calibrate the depth of the device within the uterine cavity. The starting position is marked 6 cm from the end of the device (inside the uterine cavity), with markings every 1 cm thereafter. The device is made of silicone, an inert material with excellent biocompatibility, allowing it to remain in the uterine cavity for extended periods, preventing the device materials from affecting endometrial repair and reducing the risk of infection.

[0021] like Figure 2As shown, the main body 1 includes a diaphragm 6, a uterine-shaped silicone ring 7, and a drug-releasing balloon 8. The drug-releasing balloon 8 is connected to the connecting tube 2 and is a flat, round, balloon-like structure. Four drug-releasing holes are opened on its front and back surfaces respectively for releasing the intrauterine therapeutic drug injected by the connecting tube 2. The four drug-releasing holes are arranged in a square array, so that the intrauterine injected drug can be evenly and effectively distributed to the entire inner surface of the uterine cavity and avoid blockage of the drug-releasing holes. The uterine-shaped silicone ring 7 is a solid silicone cylindrical body that forms a ring-shaped structure around the shape of the uterine cavity. It matches the shape of the uterine cavity, helps to fit the inside of the uterine cavity and reduce the pressure of the device on the endometrium. By strengthening the support around the uterine cavity, the recurrence of periuterine adhesions is reduced. The lower end of the uterine-shaped silicone ring 7 is fixedly connected to the connecting tube 2. A diaphragm 6 is set in the area between the uterine-shaped silicone ring 7, the connecting tube 2 and the drug-releasing balloon 8. The diaphragm 6 is a single-layer silicone membrane, which increases the surface area of ​​the intrauterine device body 1, so that the front and back walls of the uterine cavity are fully isolated, thereby reducing the recurrence of central uterine adhesions. The uterine-shaped silicone ring 7 further increases the strength of the intrauterine device body 1 and reduces the risk of deformation. The diaphragm 6 is provided with a placement rod connection bayonet 5 and a mounting hole 9. The placement rod connection bayonet 5 is a crescent-shaped hollow, used for the placement rod slot 12 to clamp the uterine-shaped silicone ring 7 and place the device body 1 in the correct position in the uterine cavity; such as Figure 5 As shown, the placement rod is an intrauterine contraceptive device placement rod, and the placement rod slot 12 is a U-shaped slot. There are four mounting holes 9 for mounting a detachable buckle 10, an intrauterine environment detection device or an intrauterine drug concentration detection device. Figure 3 As shown, the detachable buckle 10 is a hollow cylindrical structure with an I-shaped cross-section, which can be used to fix the repair membrane placed in the uterine cavity; for example, amniotic membrane, stem cell scaffold and other anti-adhesion membranous tissue biomembrane materials used for endometrial repair after intrauterine adhesion surgery. Specifically, the amniotic membrane and other biomembrane materials are first covered on the front and back sides of the main body 1, and then the detachable buckle 10 is installed, and the biomembrane is pushed into the connecting hole so that it can be stably and effectively fixed on the device and placed in the uterine cavity together with the device; and the through hole of the detachable buckle 10 is a storage bin for placing sustained-release drugs, nanomaterials or biomaterials, such as amniotic stem cells, stem cells, extracellular vesicles, cerium oxide nanocrystals, etc., so that they are gradually released in the intrauterine environment.

[0022] The one-way valve 3 for drug injection is connected to the open end of the connecting pipe. Figure 4As shown, the one-way valve 3 for drug injection is designed to imitate the structure of venous valves, and has two semicircular silicone sheets 11 supporting each other. When no drug syringe is inserted, it remains in a closed state to ensure the isolation between the intrauterine environment and the external environment, reducing the risk of infection. When administering the drug, the syringe is inserted into the one-way valve 3 for drug injection to push the two semicircular silicone sheets 11 apart and then inject the drug, ensuring that the drug flows in one direction, so that the drug can effectively resist the uterine cavity. After the syringe is pulled out, the two semicircular silicone sheets 11 close together and return to a closed state, avoiding the backflow of the drug in the uterine cavity, so that the injected drug can effectively act on the uterine cavity, and maintain the relevant closure of the intrauterine environment and reduce the risk of infection and injury caused by repeated catheterization during drug treatment, as well as the risk of infection caused by long-term retention.

Claims

1. A multifunctional intrauterine adhesion prevention and treatment device, characterized in that: It includes a main body, a connecting tube and a one-way valve for drug injection; wherein the main body is composed of a diaphragm, a uterine-shaped silicone ring and a drug-releasing balloon; the drug-releasing balloon is connected to the connecting tube, and the drug-releasing balloon is provided with a drug-releasing hole; the uterine-shaped silicone ring is fixedly connected to one end of the connecting tube, and a diaphragm is arranged in the area between the uterine-shaped silicone ring, the connecting tube and the drug-releasing balloon; a rod connection socket and a mounting hole are arranged on the diaphragm; the one-way valve for drug injection is connected to the other end of the connecting tube; and two semicircular silicone sheets supporting each other are arranged inside the one-way valve for drug injection.

2. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: It also includes a detachable buckle, which is a columnar structure with an I-shaped section, and the detachable buckle is clamped in the installation hole.

3. The multifunctional intrauterine adhesion prevention and treatment device as claimed in claim 2, characterized in that: The detachable buckle is provided with a through hole along the axial direction.

4. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: The drug releasing balloon is a flat balloon.

5. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: The front and rear surfaces of the drug release balloon are each provided with four drug release holes arranged in a square array.

6. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: The diaphragm is a silica gel membrane.

7. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: The connection socket of the placement rod is a crescent-shaped hollow.

8. The multifunctional intrauterine adhesion prevention and treatment device according to claim 1, characterized in that: A depth mark is provided on the connecting tube for marking the depth of the main body in the uterine cavity.

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