An animal heart simulation uterus containing a presser and a preparation method thereof

Abstract

The present invention relates to an animal heart - simulated uterus containing a presser. The simulated uterus includes a presser and a primary uterine mold. The presser includes an upper mold and a lower mold. The primary uterine mold is made from an animal heart and has a cavity structure with an open lower end. The outer wall of the primary uterine mold fits against the inner wall of the presser. One end of the primary uterine mold is provided with a uterine orifice. The part of the primary uterine mold that fits against the upper opening is the uterine horn, and the part of the primary uterine mold between the two uterine horns is the uterine fundus. The part of the primary uterine mold from the uterine orifice to the uterine horn is successively the cervix and the uterine body. The method for preparing the simulated uterus at least includes: selecting a biological tissue material, performing pretreatment, putting it into the presser and cutting off the excess animal heart muscle outside the presser, and aligning the upper mold with the lower mold. By preparing this animal heart - simulated uterus, an anatomical model of a simulated uterus is constructed, and at the same time, the simulated uterus can withstand a certain pressure for uterine cavity inflation during hysteroscopic surgery, ensuring the normal progress of simulated hysteroscopic surgery.

Description

Technical Field

[0001] The present invention relates to the technical field of medical models, and particularly relates to an animal heart-simulated uterus containing a presser and a preparation method thereof. Background Art

[0002] With the improvement of the living rhythm and living standard, people have more and more types of diseases, especially gynecological diseases of women, such as abnormal uterine bleeding, excessive or scanty menstruation, uterine polyps, uterine fibroids, etc. The traditional diagnostic methods for these gynecological diseases are: B-ultrasound examination, diagnostic curettage or case diagnosis after hysterectomy. These diagnostic methods all have their deficiencies and a high missed diagnosis rate. With the development of hysteroscopy technology, the detection rate of gynecological diseases has been significantly improved. At the same time, the treatment effects of some gynecological diseases have also been significantly improved. At present, hysteroscopy technology can be used to directly examine the lesions in the uterine cavity, perform positioning to collect the diseased tissues for examination, and at the same time, it can remove the endometrium, submucous myomas, endometrial polyps, etc. Hysteroscopic surgery does not require laparotomy, significantly shortens the postoperative recovery time, and there is no incision in the uterus, greatly reducing the probability of cesarean section in the future.

[0003] Currently, during clinical teaching and practical operation, since practice cannot be carried out on patients, simulation practice needs to be carried out on models. However, most of the existing uterine models are made of non-biological materials, which cannot give students a real clinical experience and cannot provide students with the opportunity for practical operation. This makes students have to accumulate experience only by observing the operations of teachers during long-term clinical internships, resulting in an extended learning cycle for students and poor teaching effects. Summary of the Invention

[0004] The present invention provides an animal heart-simulated uterus containing a presser and a preparation method thereof to solve the technical problems of poor teaching effects of the current uterine model and inability to simulate the realism of clinical surgical operations.

[0005] The specific solution of the present invention is: an animal heart-simulated uterus containing a presser, which includes a presser and a uterine primary mold located in the presser.

[0006] Preferably, the presser includes an upper mold and a lower mold symmetrically arranged. A mold cavity for accommodating the uterine primary mold is provided in the upper mold. A lower opening is provided at one end of the upper mold, and upper openings are provided on both sides at the other end of the upper mold.

[0007] Preferably, the uterine primary mold is made of an animal heart. The uterine primary mold is a hollow structure with an opening at the lower end. The outer wall of the uterine primary mold fits with the inner wall of the presser. An uterine orifice is provided at one end of the uterine primary mold. The part of the uterine primary mold that fits with the upper opening is the uterine horn. The uterine primary mold between the two uterine horns is the uterine fundus. The uterine primary mold from the uterine orifice to the uterine horn is successively the cervix and the uterine body from bottom to top.

[0008] Preferably, the simulated uterus further includes a simulated uterine polyp, which includes animal heart muscle fragments. One end of the animal heart muscle fragments penetrates through the outer wall of the initial uterine mold and extends into the inner cavity of the initial uterine mold.

[0009] Preferably, a catheter is inserted through the animal heart muscle fragments. The end of the catheter located in the animal heart muscle fragments is flush with the inner wall of the initial uterine mold. The other end of the catheter extends outside the presser and is connected to an infusion device. The end of the infusion device communicates with a blood bag containing simulated blood.

[0010] Preferably, the catheter is selected from a silicone catheter or a pediatric scalp vein needle catheter, and the inner diameter of the silicone catheter is 1.0 - 1.5 mm.

[0011] Preferably, the animal heart is selected from any one of a pig heart, a cow heart, or a sheep heart.

[0012] A preparation method of an animal heart - simulated uterus containing a presser includes at least the following steps:

[0013] S1. Select a fresh animal heart as the raw material;

[0014] S2. Pretreat the animal heart selected in step S1 to obtain an initial uterine mold;

[0015] S3. Place the initial uterine mold obtained in step S2 into the mold cavity of the lower mold of the presser, and adjust the position of the initial uterine mold in the mold cavity so that each part of its outer wall fits tightly against the inner wall of the mold cavity;

[0016] S4. Cut off the animal heart muscle outside the presser of the initial uterine mold in step S3, and keep the obtained animal heart muscle fragments for later use;

[0017] S5. Align the upper mold and the lower mold of the presser, and then use a fixing band to apply pressure and fix the upper mold and the lower mold, thereby obtaining the animal heart - simulated uterus containing the presser.

[0018] Preferably, the pretreatment of the animal heart includes the following steps:

[0019] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the animal heart and the septum inside the animal heart to make the chambers of the animal heart communicate with each other;

[0020] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the animal heart outward to thin the thickness of the myocardial tissue of the animal heart, and keep the outer surface of the animal heart and the myocardial tissue 1.0 - 1.5 cm below the outer surface of the animal heart;

[0021] S23, turning over: turning the thinned inner wall of the animal heart outward from the opening at the top of the animal heart, so that the outer wall of the animal heart is turned over to become the inner surface, thereby obtaining a preliminary mold of the uterus.

[0022] Preferably, step S3 specifically comprises: inserting the tip of the uterine initial mold into the uterine angle mold cavity on one side of the press, and manually adjusting the position of the uterine initial mold in the mold cavity so that the uterine initial mold fits tightly with all parts of the inner wall of the mold cavity.

[0023] Preferably, the method also includes the preparation of simulated uterine polyps, and the specific preparation method is: select a piece of animal heart muscle fragments obtained in step S4, insert one end of a catheter with an inner diameter of 1.0-1.5 mm into the middle of the selected animal heart muscle fragment, the other end of the catheter is connected to an infusion set, and the other end of the infusion set is connected to a blood bag, and the blood bag contains simulated blood; after step S4, insert the prepared simulated uterine polyp into the interior of the uterine initial mold through the edge of the press, the end of the simulated uterine polyp passes through the press and extends into the inner cavity of the uterine initial mold, and the end of the catheter located in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

[0024] Compared with the prior art, the present invention has the following advantages: the simulated uterus of the present invention comprises a press fit device and a uterine model made of an animal heart, the simulated uterus has the appearance of a uterus, and the simulated uterus has uterine structures such as a uterine os, a cervix, a uterine body, a uterine horn, a fallopian tube opening, and a uterine fundus, and constructs the anatomical structure of a simulated uterus, which is convenient for students to observe and simulate through a hysteroscope, and the uterine model made of an animal heart can give students a sense of touch and experience of a real uterus, improve their clinical experience, and speed up the speed of students' skill mastering; in addition, the press fit device plays a certain protective role on the uterine model, so that the simulated uterus can withstand a certain uterine expansion pressure during hysteroscopic surgery, avoid opening the uterine model when using a uterine expansion pump, and ensure the smooth progress of the simulated hysteroscopic surgery. By setting simulated uterine polyps and simulated blood vessels in the simulated uterus, it is convenient for students to perform simulated operations of endometrial polypectomy in the simulated uterus. Due to the setting of the simulated blood vessels, it is convenient to judge whether the depth of simulated uterine polypectomy is appropriate by whether simulated blood flows out of the simulated blood vessels, and it also improves the students' real experience, which is convenient for them to quickly master related surgical operations. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a structural schematic diagram of the upper mold and the lower mold of the present invention;

[0026] Figure 2 It is a cross-sectional view of the connection relationship between the lower mold and the uterus initial mold of the present invention;

[0027] Figure 3 It is a schematic diagram of the connection relationship between the simulated uterine polyp and the uterine initial model of the present invention. Detailed Description of the Invention

[0028] The content of the present invention can be more easily understood by referring to the following detailed description of the preferred embodiments of the present invention and the included examples. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the definitions in this specification shall prevail. As used herein, the term "prepared from" is synonymous with "comprising". The terms "comprising", "including", "having", "containing", or any other variation thereof used herein are intended to cover a non-exclusive inclusion. For example, a composition, step, method, article, or apparatus that comprises the recited elements is not necessarily limited to those elements, but may include other elements not expressly listed or elements inherent to such composition, step, method, article, or apparatus.

[0029] The connecting phrase "consisting of" excludes any unrecited element, step, or component. If used in a claim, this phrase will render the claim closed, so that it does not include materials other than those described, except for conventional impurities associated therewith. When the phrase "consisting of" appears in a clause of the claim's subject matter, rather than immediately following the subject, it limits only the elements described in that clause; other elements are not excluded from the claim as a whole.

[0030] When an equivalent, concentration, or other value or parameter is expressed as a range, a preferred range, or a range defined by a series of upper preferred values and lower preferred values, this should be understood to specifically disclose all ranges formed by any pairing of any upper range limit or preferred value with any lower range limit or preferred value, whether or not the ranges are separately disclosed. For example, when the range "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2", "1 to 2 and 4 to 5", "1 to 3 and 5", etc. When a numerical range is described herein, unless otherwise stated, the range is intended to include its end values and all integers and fractions within the range.

[0031] The singular form includes plural referents unless the context clearly dictates otherwise. "Optional" or "any one" means that the subsequently described matter or event may or may not occur, and the description includes both the case where the event occurs and the case where the event does not occur.

[0032] Approximate terms in the specification and claims are used to modify quantities, indicating that the present invention is not limited to the specific quantity, but also includes modified parts that are close to the quantity and acceptable without causing changes to the relevant basic functions. Correspondingly, modifying a numerical value with "about", "approximately", etc. means that the present invention is not limited to the exact numerical value. In some examples, the approximate term may correspond to the accuracy of the instrument for measuring the numerical value. In the specification and claims of the present application, range limitations can be combined and / or interchanged, and if not otherwise stated, these ranges include all sub-ranges contained therein.

[0033] In addition, the indefinite articles "a" and "an" before the elements or components of the present invention do not limit the quantity requirement (i.e., the number of occurrences) of the elements or components. Therefore, "a" or "an" should be interpreted as including one or at least one, and the singular form of the element or component also includes the plural form, unless the quantity clearly refers to the singular form.

[0034] In the first aspect of the present invention, there is provided an animal heart-simulating uterus containing a presser, as Figure 1 and Figure 2 shown. The simulating uterus includes a presser 1 and a primary uterine mold 2 located in the presser 1. Among them, the presser 1 has the outer shape of the uterus and includes an upper mold 3 and a lower mold 4 symmetrically arranged. A mold cavity 5 for accommodating the primary uterine mold 2 is provided in the upper mold 3. A lower opening 6 is provided at one end of the upper mold 3, and upper openings 7 are provided on both sides of the other end of the upper mold 3. The upper mold 3 and the lower mold 4 have the same structure, and the upper mold 3 and the lower mold 4 can be detachably fitted or hinged through a connecting member. After the upper mold 3 and the lower mold 4 are buckled together, a uterine orifice mold cavity 8 is formed at the lower opening 6 of the upper mold 3 and the lower mold 4, a uterine horn mold cavity 9 is formed at the upper openings 7 of the upper mold 3 and the lower mold 4, a uterine fundus mold cavity 10 is formed at the presser 1 between the two upper openings 7, and the side wall of the presser 1 between the lower opening 6 and the upper opening 7 sequentially forms a cervical mold cavity 11 and a uterine body mold cavity 12 from bottom to top.

[0035] The uterine primary mold 2 is made of an animal heart, and the animal heart is preferably a pig heart, a sheep heart, or a bovine heart. The uterine primary mold 2 is a cavity structure with an open lower end, and the cavity of the uterine primary mold 2 constitutes the uterine cavity 22 of the simulated uterus. Since the outer wall of the uterine primary mold 2 fits against the inner wall of the presser 1, the outer shape of the uterine primary mold 2 is consistent with that of the presser 1, and further makes the outer shape of the uterine primary mold 2 consistent with that of the uterus, enabling students to observe the outer shape of the uterus through this simulated uterus. At the same time, an ostium 13 is provided at one end of the uterine primary mold 2, and the ostium 13 is located at the ostium mold cavity 8 of the presser. The part where the uterine primary mold 2 fits against the upper opening 7 is the uterine horn 14, the part of the uterine primary mold 2 between the two uterine horns 14 is the uterine fundus 15, and the uterine primary mold 2 from the ostium 13 to the uterine horn 14 is successively the cervix 16 and the uterine body 17 from bottom to top. Through the above settings, the simulated uterus has a shape similar to that of the real uterus, and at the same time has the structures of the uterine cavity 22, uterine horn 14, uterine fundus 15, uterine body 17, cervix 16, and ostium 13, fully simulating the structure of the real uterus, thus constructing the anatomical structure of the simulated uterus and facilitating giving students a real clinical experience during teaching. In addition, when using a hysteroscope to perform simulated operations on the simulated uterus, it is necessary to apply pressure to the simulated uterus through a hysterostat, and the hysterostatic pressure is generally set at 60 - 80 mmHg. The presence of the presser 1 enables the simulated uterus to withstand this pressure, preventing the uterine primary mold 2 from bursting and playing a certain protective role for the uterine primary mold 2, so that students can truly simulate the operation of the hysterostat during clinical operations and ensure the normal progress of the simulated operation.

[0036] To facilitate students' simulated operation of uterine polyp resection during teaching and improve their practical operation ability, the simulated uterus further includes a simulated uterine polyp 18, and the simulated uterine polyp 18 includes animal heart muscle fragments 19. One end of the animal heart muscle fragments 19 passes through the outer wall of the uterine primary mold 2 and extends into the inner cavity of the uterine primary mold 2. During the teaching and training process, when students observe the simulated uterine polyp 18, they can perform resection on it, so as to enable students to simulate the operation process of removing the simulated uterine polyp 18, enhance their clinical experience, and improve their practical operation ability.

[0037] Further, to facilitate students in understanding whether the depth of excising the simulated uterine polyp 18 is appropriate, a catheter 20 is inserted into the animal heart muscle fragment 19. The inner diameter of the catheter 20 is relatively small, and the end of the catheter 20 located in the animal heart muscle fragment is flush with the inner wall of the uterine primary mold 2. The other end of the catheter 20 extends outside the presser 1 and is connected to an infusion set 21. The end of the infusion set 21 is communicated with a blood bag (not shown in the figure), and the blood bag is filled with simulated blood. When the depth of the simulated uterine polyp 18 excised by the student is too deep, the simulated blood will flow out from the end of the catheter 20 into the inner cavity of the uterine primary mold 2 and can be observed through the display of the hysteroscope. The position and number of the simulated uterine polyps 18 are not specifically limited here and can be selected accordingly according to teaching needs. The inner diameter of the catheter 20 is 1.0 - 1.5 mm. Preferably, the catheter 20 is a silicone catheter or a pediatric scalp vein needle catheter.

[0038] Usage method: In teaching training, students first set the pressure of the uterine distension pump, and the pressure value is 60 - 80 mmHg. After confirming that the air bubbles in the uterine distension pipeline have been emptied, then hold the hysteroscope and enter the uterine cavity 22 from the uterine orifice 13 of the simulated uterus, and sequentially explore the uterine fundus 15, bilateral uterine horns 14, bilateral fallopian tube orifices, anterior and posterior walls, bilateral walls, isthmus, and cervical canal of the simulated uterus. If the simulated uterine polyp 18 is detected during the exploration process, then excise the simulated uterine polyp 18, and observe through the display of the hysteroscope whether it is completely excised and whether the excision depth is appropriate. If the excision depth is inappropriate, the simulated blood will flow out; after the excision and exploration are completed, check for active bleeding and slowly withdraw the hysteroscope, and the simulation process ends.

[0039] The second aspect of the present invention provides a preparation method of the above-mentioned animal heart - simulated uterus containing the presser 1, and this preparation method at least includes the following steps:

[0040] S1. Select a fresh animal heart as the raw material. Any animal heart similar in size to the human uterus can be used to prepare the simulated uterus, preferably any one of a pig heart, a cow heart, and a sheep heart;

[0041] S2. Pretreat the animal heart selected in step S1 to obtain the uterine primary mold 2;

[0042] S3. Place the uterine primary mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the presser 1, and adjust the position of the uterine primary mold 2 in the mold cavity 5 to make all parts of the outer wall of the uterine primary mold 2 closely fit with the inner wall of the mold cavity 5;

[0043] S4. Cut off the animal heart muscle outside the presser 1 of the uterine primary mold 2 in step S3, and keep the obtained animal heart muscle fragment 19 for later use;

[0044] S5. Align the upper die 3 and the lower die 4 of the above laminator 1, and then use a fixing strap to apply pressure and fix the upper die 3 and the lower die 4, thereby obtaining the animal heart simulation uterus containing the laminator 1. Among them, the fixing strap is preferably a cable tie or a bandage.

[0045] The pretreatment of the animal heart includes the following steps:

[0046] S21. Connect: Use surgical scissors to cut the chordae tendineae of the animal heart and the septum inside the animal heart, so that the chambers of the animal heart are connected;

[0047] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the animal heart outward to thin the thickness of the myocardial tissue of the animal heart, and retain the myocardial tissue on the outer surface of the animal heart and 1.0 - 1.5 cm below the outer surface of the animal heart;

[0048] S23. Flip: Flip the inner wall of the thinned animal heart outward from the opening at the top of the animal heart, so that the outer wall of the animal heart is flipped to become the inner surface, thereby obtaining the initial uterine mold 2.

[0049] Step S3 is specifically: Insert the pointed end of the initial uterine mold 2, that is, the apex of the animal heart, into the uterine horn mold cavity on one side of the laminator 1, and manually adjust the position of the initial uterine mold 2 in the mold cavity 5 to make the initial uterine mold 2 fit tightly with all parts of the inner wall of the mold cavity 5.

[0050] Through the above steps, the simulation uterus is obtained. The simulation uterus contains the laminator 1 and the initial uterine mold 2. Due to the presence of the laminator 1, the simulation uterus has the shape of the uterus, and at the same time has the structures of the uterine horn 14, the cervix 16, the uterine cavity 22, the uterine fundus 15, the uterine body 17, and the uterine orifice 13, constructing an anatomical model of the simulated uterus. In addition, the presence of the laminator 1 enables the simulation uterus to withstand a certain uterine distension pressure without bursting, ensuring the normal progress of the simulation operation.

[0051] Furthermore, the method also includes the preparation of the simulated uterine polyp 18. The specific preparation method is: Select a piece from the animal heart muscle fragments 19 cut off in step S4. Insert one end of the catheter 20 into the middle of the selected animal heart muscle fragment 19. The other end of the catheter 20 is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. The inner diameter of the catheter 20 is 1.0 - 1.5 mm, and the catheter 20 is selected from a silicone catheter or a pediatric scalp vein needle catheter.

[0052] Since the wall thickness of the uterine primary mold 2 is only 1.0 - 1.5 cm due to the thinning of the animal heart in step S22, after the uterine primary mold 2 outside the presser 1 is excised in step S4, an opening will be formed at the edge of the uterine primary mold 2 around the presser 1. The prepared simulated uterine polyp 18 is inserted into the interior of the uterine primary mold 2 through this opening. The end of the simulated flesh, that is, the end without the catheter 20, passes through the presser 1 and extends into the inner cavity of the uterine primary mold 2, and the end of the small catheter 20 in the simulated uterine polyp 18 is flush with the inner wall of the uterine primary mold 2.

[0053] Example 1

[0054] S1. Select a fresh pig heart as the raw material;

[0055] S2. Pretreat the pig heart selected in step S1 to obtain the uterine primary mold 2, specifically as follows:

[0056] S21. Connect: Use surgical scissors to cut the chordae tendineae of the pig heart and the septum inside the pig heart to make the chambers of the pig heart communicate with each other;

[0057] S22. Thin: Use surgical scissors to excise the myocardial tissue from the inner wall of the pig heart outward to thin the thickness of the myocardial tissue of the pig heart, and retain the outer surface of the pig heart and 1.0 cm of myocardial tissue under the outer surface of the pig heart;

[0058] S23. Flip: Flip the inner wall of the thinned pig heart outward from the opening at the top of the pig heart so that the outer wall of the pig heart is turned into the inner surface, thereby obtaining the uterine primary mold 2;

[0059] S3. Place the uterine primary mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the presser 1, and insert the pointed end of the uterine primary mold 2, that is, the apex of the pig heart, into the uterine horn 14 on one side of the presser 1, and manually adjust the position of the uterine primary mold 2 in the mold cavity 5 to make all parts of the uterine primary mold 2 fit tightly against the inner wall of the mold cavity 5.

[0060] S4. Cut off the pig heart muscle outside the presser 1 of the uterine primary mold 2 in step S3, and retain the cut pig heart muscle fragments for later use;

[0061] S5. Align the upper mold 3 and the lower mold 4 of the above-mentioned presser 1, and then use a cable tie to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart - simulated uterus containing the presser 1.

[0062] Example 2

[0063] S1. Select a fresh pig heart as the raw material;

[0064] S2. Pretreat the pig heart selected in step S1 to obtain the uterine primary mold 2, specifically as follows:

[0065] S21. Connection: Use surgical scissors to cut the chordae tendineae of the pig heart and the septum inside the pig heart to connect the chambers of the pig heart;

[0066] S22. Thinning: Use surgical scissors to cut the myocardial tissue from the inner wall of the pig heart outward to thin the thickness of the myocardial tissue of the pig heart, and retain the outer surface of the pig heart and the myocardial tissue 1.5 cm below the outer surface of the pig heart;

[0067] S23. Inversion: Invert the inner wall of the thinned pig heart outward from the opening at the top of the pig heart, so that the outer wall of the pig heart is inverted into the inner surface, thereby obtaining the initial uterine mold 2;

[0068] S3. Place the initial uterine mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the press 1, and insert the pointed end of the initial uterine mold 2, that is, the apex of the pig heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the initial uterine mold 2 in the mold cavity 5 so that all parts of the initial uterine mold 2 are in close contact with the inner wall of the mold cavity 5.

[0069] S4. Cut off the pig heart muscle outside the press 1 of the initial uterine mold 2 in step S3, and retain the cut pig heart muscle fragments for later use; Select one piece from the cut pig heart muscle fragments and insert it into the initial uterine mold through the edge of the press;

[0070] S5. Close the upper mold 3 and the lower mold 4 of the above press 1, and then use a tie to apply pressure to fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart simulated uterus containing the press 1.

[0071] Example 3

[0072] S1. Select a fresh pig heart as the raw material;

[0073] S2. Pretreat the pig heart selected in step S1 to obtain the initial uterine mold 2, specifically as follows:

[0074] S21. Connection: Use surgical scissors to cut the chordae tendineae of the pig heart and the septum inside the pig heart to connect the chambers of the pig heart;

[0075] S22. Thinning: Use surgical scissors to cut the myocardial tissue from the inner wall of the pig heart outward to thin the thickness of the myocardial tissue of the pig heart, and retain the outer surface of the pig heart and the myocardial tissue 1.2 cm below the outer surface of the pig heart;

[0076] S23. Inversion: Invert the inner wall of the thinned pig heart outward from the opening at the top of the pig heart, so that the outer wall of the pig heart is inverted into the inner surface, thereby obtaining the initial uterine mold 2;

[0077] S3. Place the initial uterine mold 2 obtained in step S2 into the cavity 5 of the lower mold 4 of the press 1. Insert the pointed end of the initial uterine mold 2, which is the apex of the pig heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the initial uterine mold 2 in the cavity 5 to make all parts of the inner wall of the initial uterine mold 2 closely fit the inner wall of the cavity 5.

[0078] S4. Cut off the pig heart muscle outside the press 1 of the initial uterine mold 2 in step S3, and keep the cut pig heart muscle fragments for later use. Select one piece from the cut pig heart muscle fragments, insert one end of the catheter into the middle of the selected pig heart muscle fragment. The inner diameter of the catheter is 1.0 mm. The other end of the catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag is filled with simulated blood. Insert the prepared simulated uterine polyp into the initial uterine mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the initial uterine mold. The end of the catheter located in the simulated uterine polyp is flush with the inner wall of the initial uterine mold.

[0079] S5. Close the upper mold 3 and the lower mold 4 of the above press 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart simulated uterus containing the press 1.

[0080] Example 4

[0081] S1. Select a fresh pig heart as the raw material.

[0082] S2. Pretreat the selected pig heart in step S1 to obtain the initial uterine mold 2, specifically as follows:

[0083] S21. Connect: Use surgical scissors to cut the chordae tendineae of the pig heart and the septum inside the pig heart to connect all the chambers of the pig heart.

[0084] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the pig heart outward to thin the thickness of the myocardial tissue of the pig heart, and keep the outer surface of the pig heart and the myocardial tissue 1.3 cm below the outer surface of the pig heart.

[0085] S23. Flip: Flip the inner wall of the thinned pig heart outward from the opening at the top of the pig heart so that the outer wall of the pig heart becomes the inner surface, thereby obtaining the initial uterine mold 2.

[0086] S3. Place the initial uterine mold 2 obtained in step S2 into the cavity 5 of the lower mold 4 of the press 1. Insert the pointed end of the initial uterine mold 2, which is the apex of the pig heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the initial uterine mold 2 in the cavity 5 to make all parts of the inner wall of the initial uterine mold 2 closely fit the inner wall of the cavity 5.

[0087] S4. Cut off the porcine heart muscle outside the press 1 of the uterine primary mold 2 in step S3, and keep the cut porcine heart muscle fragments for later use. Select one piece from the cut porcine heart muscle fragments, insert one end of the catheter into the middle of the selected porcine heart muscle fragment. The inner diameter of the catheter is 1.5 mm. The other end of the catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. Insert the prepared simulated uterine polyp into the uterine primary mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the uterine primary mold. The end of the catheter located in the simulated uterine polyp is flush with the inner wall of the uterine primary mold.

[0088] S5. Align the upper mold 3 and the lower mold 4 of the above-mentioned press 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, so as to obtain the animal heart-simulated uterus containing the press 1.

[0089] Example 5

[0090] S1. Select a fresh porcine heart as the raw material;

[0091] S2. Pretreat the porcine heart selected in step S1 to obtain the uterine primary mold 2, specifically as follows:

[0092] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the porcine heart and the septum inside the porcine heart to connect the cavities of the porcine heart;

[0093] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the porcine heart outward to thin the thickness of the myocardial tissue of the porcine heart, and keep the outer surface of the porcine heart and the myocardial tissue 1.5 cm below the outer surface of the porcine heart;

[0094] S23. Turn over: Turn the inner wall of the thinned porcine heart outward from the opening at the top of the porcine heart, so that the outer wall of the porcine heart is turned into the inner surface, thus obtaining the uterine primary mold 2;

[0095] S3. Place the uterine primary mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the press 1, and insert the pointed end of the uterine primary mold 2, that is, the apex of the porcine heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the uterine primary mold 2 in the mold cavity 5 to make the uterine primary mold 2 closely fit with all parts of the inner wall of the mold cavity 5.

[0096] S4. Cut off the porcine heart muscle outside the press 1 of the uterine primary mold 2 in step S3, and keep the cut porcine heart muscle fragments for later use. Select one piece from the porcine heart muscle fragments cut off in step S4, insert one end of the catheter into the middle of the selected porcine heart muscle fragment. The inner diameter of the catheter is 1.2 mm. The other end of the catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. Insert the prepared simulated uterine polyp into the uterine primary mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the uterine primary mold. The end of the catheter located in the simulated uterine polyp is flush with the inner wall of the uterine primary mold.

[0097] S5. Align the upper mold 3 and the lower mold 4 of the above press 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart-simulated uterus containing the press 1.

[0098] Example 6

[0099] S1. Select a fresh porcine heart as the raw material;

[0100] S2. Pretreat the porcine heart selected in step S1 to obtain the uterine primary mold 2, specifically as follows:

[0101] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the porcine heart and the septum inside the porcine heart to connect the cavities of the porcine heart;

[0102] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the porcine heart outward to thin the thickness of the myocardial tissue of the porcine heart, and keep the outer surface of the porcine heart and the myocardial tissue 1.3 cm below the outer surface of the porcine heart;

[0103] S23. Turn over: Turn the inner wall of the thinned porcine heart outward from the opening at the top of the porcine heart so that the outer wall of the porcine heart is turned into the inner surface, thereby obtaining the uterine primary mold 2;

[0104] S3. Place the uterine primary mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the press 1, and insert the pointed end of the uterine primary mold 2, that is, the apex of the porcine heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the uterine primary mold 2 in the mold cavity 5 so that the uterine primary mold 2 is in close contact with all parts of the inner wall of the mold cavity 5.

[0105] S4. Cut off the porcine heart muscle outside the uterine initial mold 2 in step S3, and save the cut porcine heart muscle fragments for later use. Select one piece from the porcine heart muscle fragments cut off in step S4, insert one end of the silicone catheter into the middle of the selected porcine heart muscle fragment. The inner diameter of the silicone catheter is 1.5 mm. The other end of the silicone catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. Insert the prepared simulated uterine polyp into the uterine initial mold through the edge of the presser, and the end of the simulated uterine polyp passes through the presser and extends into the inner cavity of the uterine initial mold. The end of the silicone catheter in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

[0106] S5. Align the upper mold 3 and the lower mold 4 of the above-mentioned presser 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, so as to obtain the animal heart-simulated uterus containing the presser 1.

[0107] Example 7

[0108] S1. Select a fresh porcine heart as the raw material;

[0109] S2. Pretreat the porcine heart selected in step S1 to obtain the uterine initial mold 2, specifically as follows:

[0110] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the porcine heart and the septum inside the porcine heart to connect the chambers of the porcine heart;

[0111] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the porcine heart outward to thin the thickness of the myocardial tissue of the porcine heart, and retain the myocardial tissue on the outer surface of the porcine heart and 1.5 cm below the outer surface of the porcine heart;

[0112] S23. Flip: Flip the inner wall of the thinned porcine heart outward from the opening at the top of the porcine heart, so that the outer wall of the porcine heart becomes the inner surface, thereby obtaining the uterine initial mold 2;

[0113] S3. Place the uterine initial mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the presser 1, and insert the pointed end of the uterine initial mold 2, that is, the apex of the porcine heart, into the uterine horn 14 on one side of the presser 1, and manually adjust the position of the uterine initial mold 2 in the mold cavity 5 to make all parts of the uterine initial mold 2 in close contact with the inner wall of the mold cavity 5.

[0114] S4. Cut off the porcine heart muscle outside the press 1 of the uterine initial mold 2 in step S3, and keep the cut porcine heart muscle fragments for later use. Select one piece from the porcine heart muscle fragments cut off in step S4, insert one end of the silicone catheter into the middle of the selected porcine heart muscle fragment. The inner diameter of the silicone catheter is 1.0 mm. The other end of the silicone catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. Insert the prepared simulated uterine polyp into the uterine initial mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the uterine initial mold. The end of the silicone catheter located in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

[0115] S5. Align the upper mold 3 and the lower mold 4 of the above-mentioned press 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart-simulated uterus containing the press 1.

[0116] Example 8

[0117] S1. Select a fresh bovine heart as the raw material;

[0118] S2. Pretreat the bovine heart selected in step S1 to obtain the uterine initial mold 2, specifically as follows:

[0119] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the bovine heart and the septum inside the bovine heart to make the chambers of the bovine heart communicate with each other;

[0120] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the bovine heart outward to thin the thickness of the myocardial tissue of the bovine heart, and keep the outer surface of the bovine heart and the myocardial tissue 1.0 cm below the outer surface of the bovine heart;

[0121] S23. Turn over: Turn the inner wall of the thinned bovine heart outward from the opening at the top of the bovine heart so that the outer wall of the bovine heart is turned into the inner surface, thereby obtaining the uterine initial mold 2;

[0122] S3. Place the uterine initial mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the press 1, and clamp the pointed end of the uterine initial mold 2, that is, the apex of the bovine heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the uterine initial mold 2 in the mold cavity 5 so that all parts of the uterine initial mold 2 are in close contact with the inner wall of the mold cavity 5;

[0123] S4. Cut off the bovine heart muscle outside the uterine initial mold 2 in step S3, and keep the cut bovine heart muscle fragments for later use. Select one piece from the bovine heart muscle fragments cut off in step S4, insert one end of the pediatric scalp vein needle catheter into the middle of the selected bovine heart muscle fragment, connect the other end of the pediatric scalp vein needle catheter to the infusion set 21, connect the other end of the infusion set 21 to the blood bag, and the blood bag is filled with simulated blood. Insert the prepared simulated uterine polyp into the uterine initial mold through the edge of the presser, and the end of the simulated uterine polyp passes through the presser and extends into the inner cavity of the uterine initial mold. The end of the pediatric scalp vein needle catheter located in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

[0124] S5. Align the upper mold 3 and the lower mold 4 of the presser 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart-simulated uterus containing the presser 1.

[0125] Example 9

[0126] S1. Select a fresh sheep heart as the raw material;

[0127] S2. Pretreat the sheep heart selected in step S1 to obtain the uterine initial mold 2, specifically as follows:

[0128] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the sheep heart and the septum inside the sheep heart to connect the cavities of the sheep heart.

[0129] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the sheep heart outward to thin the thickness of the myocardial tissue of the sheep heart, and keep the outer surface of the sheep heart and the myocardial tissue 1.0 cm below the outer surface of the sheep heart.

[0130] S23. Flip: Flip the inner wall of the thinned sheep heart outward from the opening at the top of the sheep heart so that the outer wall of the sheep heart becomes the inner surface, thereby obtaining the uterine initial mold 2.

[0131] S3. Place the uterine initial mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the presser 1, and insert the pointed end of the uterine initial mold 2, that is, the apex of the sheep heart, into the uterine horn 14 on one side of the presser 1, and manually adjust the position of the uterine initial mold 2 in the mold cavity 5 to make the uterine initial mold 2 closely fit with all parts of the inner wall of the mold cavity 5.

[0132] S4. Cut off the sheep heart muscle outside the press 1 of the uterine initial mold 2 in step S3, and keep the cut sheep heart muscle fragments for later use. Select one piece from the cut sheep heart muscle fragments, insert one end of the silicone catheter into the middle of the selected sheep heart muscle fragment. The inner diameter of the silicone catheter is 1.2 mm. The other end of the silicone catheter is connected to the infusion set 21, and the other end of the infusion set 21 is connected to the blood bag. The blood bag contains simulated blood. Insert the prepared simulated uterine polyp into the uterine initial mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the uterine initial mold. The end of the silicone catheter in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

[0133] S5. Align the upper mold 3 and the lower mold 4 of the press 1, and then use a tie to apply pressure to fix the upper mold 3 and the lower mold 4, thereby obtaining the animal heart simulated uterus containing the press 1.

[0134] Example 10

[0135] S1. Select a fresh sheep heart as the raw material.

[0136] S2. Pretreat the selected sheep heart in step S1 to obtain the uterine initial mold 2, specifically as follows:

[0137] S21. Connect: Use surgical scissors to cut off the chordae tendineae of the sheep heart and the septum inside the sheep heart to connect the chambers of the sheep heart.

[0138] S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the sheep heart outward to thin the thickness of the myocardial tissue of the sheep heart, and keep the outer surface of the sheep heart and the myocardial tissue 1.0 cm below the outer surface of the sheep heart.

[0139] S23. Turn: Turn the inner wall of the thinned sheep heart outward from the opening at the top of the sheep heart so that the outer wall of the sheep heart becomes the inner surface, thereby obtaining the uterine initial mold 2.

[0140] S3. Place the uterine initial mold 2 obtained in step S2 into the mold cavity 5 of the lower mold 4 of the press 1, and insert the pointed end of the uterine initial mold 2, that is, the apex of the sheep heart, into the uterine horn 14 on one side of the press 1, and manually adjust the position of the uterine initial mold 2 in the mold cavity 5 so that all parts of the uterine initial mold 2 are in close contact with the inner wall of the mold cavity 5.

[0141] S4. Cut off the sheep heart muscle outside the press 1 of the uterine initial mold 2 in step S3, and keep the cut sheep heart muscle fragments for later use.

[0142] Select a piece from the sheep heart muscle fragments excised in step S4. Insert one end of the pediatric scalp vein catheter into the middle of the selected sheep heart muscle fragment. The other end of the pediatric scalp vein catheter is connected to the infusion set 21. The other end of the infusion set 21 is connected to a blood bag which contains simulated blood. Stuff the prepared simulated uterine polyp into the interior of the initial uterine mold through the edge of the press. The end of the simulated uterine polyp passes through the press and extends into the inner cavity of the initial uterine mold. The end of the pediatric scalp vein catheter located in the simulated uterine polyp is flush with the inner wall of the initial uterine mold;

[0143] S5. Align the upper mold 3 and the lower mold 4 of the press 1, and then use a bandage to apply pressure and fix the upper mold 3 and the lower mold 4, thereby obtaining a simulated uterus.

[0144] The above embodiments only exemplarily illustrate the principles and effects of the present invention, rather than limiting the present invention. Any person familiar with this technology can modify or change the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or changes completed by those with ordinary knowledge in the technical field without departing from the spirit and technical ideas disclosed by the present invention should still be covered by the claims of the present invention.

Claims

1. An animal heart-simulating uterus containing a presser, characterized in that: The simulated uterus includes a presser and a primary uterine mold located in the presser; the presser includes an upper mold and a lower mold symmetrically arranged. A mold cavity for accommodating the primary uterine mold is provided in the upper mold. A lower opening is formed at one end of the upper mold, and upper openings are formed on both sides at the other end of the upper mold; the presser has the shape of the uterus, and the shape of the primary uterine mold is consistent with that of the presser and also consistent with that of the uterus; after the upper mold and the lower mold are buckled together, a cervical orifice mold cavity is formed at the lower opening of the upper mold and the lower mold, a uterine horn mold cavity is formed at the upper openings of the upper mold and the lower mold, a uterine fundus mold cavity is formed at the presser between the two upper openings, and the side wall of the presser between the lower opening and the upper opening sequentially forms a cervical mold cavity and a uterine body mold cavity from bottom to top; The primary uterine mold is made of an animal heart.

2. The animal heart-simulating uterus containing a presser according to claim 1, characterized in that: The primary uterine mold is a cavity structure with an opening at the lower end. The outer wall of the primary uterine mold fits closely with the inner wall of the presser. An orifice is formed at one end of the primary uterine mold. The part of the primary uterine mold that fits with the upper opening is the uterine horn. The part of the primary uterine mold between the two uterine horns is the uterine fundus. The part of the primary uterine mold from the orifice to the uterine horn is sequentially the cervix and the uterine body from bottom to top.

3. The animal heart-simulating uterus containing a presser according to claim 2, wherein: The simulated uterus further includes a simulated uterine polyp, which includes animal heart muscle fragments. One end of the animal heart muscle fragments penetrates through the outer wall of the primary uterine mold and extends into the inner cavity of the primary uterine mold.

4. The animal heart-simulating uterus containing a presser according to claim 3, wherein: A catheter is inserted into the animal heart muscle fragments. The end of the catheter located in the animal heart muscle fragments is flush with the inner wall of the primary uterine mold. The other end of the catheter extends outside the presser and is connected to an infusion device. The end of the infusion device is communicated with a blood bag containing simulated blood.

5. The animal heart-simulating uterus containing a presser according to claim 4, characterized in that: The catheter is selected from a silicone catheter or a pediatric scalp vein needle catheter, and the inner diameter of the silicone catheter is 1.0 - 1.5 mm.

6. The animal heart-simulating uterus containing a presser according to claim 2, wherein: The animal heart is selected from any one of a pig heart, a cow heart or a sheep heart.

7. The preparation method of the animal heart simulation uterus containing a presser according to any one of claims 1-6, characterized in that It includes at least the following steps: S1. Select a fresh animal heart as the raw material; S2. Pretreat the animal heart selected in step S1 to obtain the primary uterine mold; S3. Place the primary uterine mold obtained in step S2 into the mold cavity of the lower mold of the presser, and adjust the position of the primary uterine mold in the mold cavity to make each part of its outer wall fit closely with the inner wall of the mold cavity; S4. Cut off the animal heart muscle outside the presser of the primary uterine mold in step S3, and keep the obtained animal heart muscle fragments for later use; S5. Align the upper mold and the lower mold of the presser, and then use a fixing band to apply pressure and fix the upper mold and the lower mold to obtain the animal heart - simulated uterus containing the presser.

8. The preparation method of the animal heart-simulating uterus containing a presser according to claim 7, characterized in that: The pretreatment of the animal heart includes the following steps: S21. Connect: Use surgical scissors to cut off the chordae tendineae of the animal heart and the septum inside the animal heart to connect the cavities of the animal heart; S22. Thin: Use surgical scissors to cut off the myocardial tissue from the inner wall of the animal heart outward to thin the thickness of the myocardial tissue of the animal heart, and keep the outer surface of the animal heart and the myocardial tissue 1.0 - 1.5 cm below the outer surface of the animal heart; S23. Turn: Turn the inner wall of the thinned animal heart outward from the opening at the top of the animal heart so that the outer wall of the animal heart is turned into the inner surface to obtain the primary uterine mold.

9. The preparation method of the animal heart simulation uterus containing a presser according to claim 8, characterized in that: Step S3 specifically includes: clamping the tip of the uterine initial mold into the uterine horn mold cavity on one side of the press-fitting device, and manually adjusting the position of the uterine initial mold in the mold cavity so that all parts of the uterine initial mold are closely attached to the inner wall of the mold cavity.

10. The preparation method of the animal heart-simulating uterus containing a presser according to claim 7, characterized in that: This method further includes the preparation of a simulated uterine polyp. The specific preparation method is as follows: Select a piece from the animal heart muscle fragments obtained in step S4. Insert one end of a catheter with an inner diameter of 1.0 - 1.5 mm into the middle of the selected animal heart muscle fragment. The other end of the catheter is connected to an infusion device, and the other end of the infusion device is connected to a blood bag containing simulated blood. After step S4, insert the prepared simulated uterine polyp into the uterine initial mold through the edge of the press-fitting device. The end of the simulated uterine polyp passes through the press-fitting device and extends into the inner cavity of the uterine initial mold, and the end of the catheter located in the simulated uterine polyp is flush with the inner wall of the uterine initial mold.

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