Portable nucleic acid detection box

Abstract

The present invention belongs to the field of pharmaceutical biotechnology technology, and specifically relates to a portable nucleic acid detection box. The portable nucleic acid detection box provided by the present invention is provided with a foldable workbench inside, and a lamp post with a sterilization effect is provided above the workbench, which saves space and avoids contamination caused by various viruses during the experimental operation and during the sampling process when detecting a virus. The portable nucleic acid detection box provided by the present invention is provided with a foldable support structure at the bottom of the workbench for reinforcing and supporting the workbench, which is convenient for operation. At the same time, the foldable design saves space, and is simple to operate and easy to use.

Description

Technical Field

[0001] The invention belongs to the technical field of medical biotechnology, and specifically relates to a portable nucleic acid detection box. Background Art

[0002] As we all know, nucleic acids are closely related to pathogenic genes and genetic diseases, gene expression regulation, cell proliferation and apoptosis, and the occurrence and development of cancer. Biological tissues, bacteria, and viruses all have unique nucleic acid sequences, and the detection of these specific sequences plays an important role in gene analysis, disease diagnosis, food contamination, forensic identification, and environmental monitoring.

[0003] With the development of science and technology, nucleic acid detection has been increasingly used in the fields of medical diagnosis, animal disease diagnosis, food safety detection, etc., and the detection of pathogens by nucleic acid has the advantages of high sensitivity and no need for users to draw blood. At present, the commonly used nucleic acid amplification methods include amplification technology based on the classical ordinary polymerase chain reaction and emerging isothermal amplification technology, such as cross-primer isothermal amplification technology, loop-mediated isothermal amplification technology, chain displacement amplification, helicase-dependent amplification, recombinant polymerase amplification, recombinase-mediated amplification, etc.

[0004] On-site testing requires fast, accurate, and simple operation, and the current common sample virus nucleic acid detection technologies include sample nucleic acid extraction, sample RNA reverse transcription, and sample DNA positive detection, all of which require professional personnel, technical equipment, and a clean environment. In addition, it takes a lot of time for samples to be sent to provincial and municipal laboratories for testing. These conditions have caused great difficulties for sample positive testing and increased the difficulty of epidemic control. There are many types of nucleic acid detection equipment on the market, and the temperature control methods for nucleic acid amplification include air heating and cooling, semiconductor refrigeration temperature control, heating film temperature control, infrared temperature control, etc. However, reagents and samples are generally reacted in PCR tubes, which have large power energy loss, large reagent and sample consumption, and have the disadvantages of high cost, large size, complex operation, and high user quality requirements.

[0005] The document with application number CN201721047532.6 discloses a portable nucleic acid detection box, including a box body and a box cover, wherein a plurality of vertical plates are vertically arranged inside the box body, and the plurality of vertical plates divide the interior of the box body into a plurality of positioning slots for placing equipment, and the plurality of vertical plates and the vertical plates and the box body are detachably connected by buckles, wherein four telescopic rod slots are provided above two vertical plates, and telescopic rods are vertically arranged in the telescopic rod slots, and a sterile workbench is fixedly arranged on the telescopic rods, and a sterile workbench placement slot matching the position of the sterile workbench is provided on the inner wall of the box cover; the utility model provides a portable nucleic acid detection box, which can realize the field on-site virus nucleic acid detection without other auxiliary facilities, and realizes the function of detection anytime and anywhere; the mobile phone Bluetooth or tablet computer is connected to the portable PCR instrument for use, and the program can be flexibly selected according to the actual situation, and the data can be monitored in real time, and the operation is simple and convenient. However, even if the operating table of the device uses the telescopic rod technology, it still occupies a relatively large space and is not convenient for carrying. Summary of the invention

[0006] In response to the above-mentioned problems, the purpose of the present invention is to provide a portable nucleic acid detection box that realizes the function of detection anywhere, and has comprehensive detection functions, simple operation, and short detection time. It can be used in various on-site rapid detection scenarios such as health and epidemic prevention departments, supervision departments, etc., and plays a role in rapid screening for timely and accurate judgment of whether the test subject is infected with the virus.

[0007] A portable nucleic acid detection box comprises a box body with a plurality of troughs for placing equipment separated by vertical boards and a box cover hinged to the box body, a workbench located at the upper end of the vertical boards is arranged in the box body, two first connecting rods hinged to the inner side walls of the box body at both ends and two second connecting rods hinged to the inner side walls of the box cover at both ends are respectively hinged to the two side ends of the workbench, and a supporting structure for supporting the workbench is arranged on the vertical boards.

[0008] A further preferred technical solution is that the supporting structure includes two supporting columns arranged in an installation groove opened on the surface of the vertical plate, and each of the supporting columns is provided with a first through hole at the end close to the side groove wall of the installation groove, and the first through hole has a connecting column with two side ends connected to the groove wall of the installation groove, and a torsion spring with one end connected to the connecting column and the other end connected to the inner wall of the first through hole.

[0009] A further preferred technical solution is that the supporting structure includes a limit column with a limit protrusion arranged on the surface of a limit groove opened on the vertical plate and a first limit block opened on the inner side wall of the limit groove and matching the second limit block, and a control block connected to the limit column, and the control block is provided with a tension spring connected to the mounting inner ring arranged inside the limit groove.

[0010] A further preferred technical solution is that a limiting inner ring is provided at the end of the inner groove wall of the limiting groove which is different from the control block.

[0011] A further preferred technical solution is that a groove adapted to the body of the limiting column is formed at the end of the second limiting block close to the limiting column.

[0012] A further preferred technical solution is that a first mark is provided on the surface of the control block and coincides with the projection of the limiting protrusion.

[0013] A further preferred technical solution is that a second mark corresponding to the first limiting block and / or the second limiting block is provided on the surface of the vertical plate.

[0014] A further preferred technical solution is that a lamp post is provided on the inner wall of the box cover.

[0015] A further preferred technical solution is that a handrail is provided on the lower end surface of the box body at the hinged connection between the box body and the box cover.

[0016] A further preferred technical solution is that a roller is provided at the lower end of the box.

[0017] In summary, the present invention has the following beneficial effects:

[0018] The portable nucleic acid detection box provided by the present invention realizes the function of detection anywhere, and has comprehensive detection functions, simple operation, and short detection time. It can be applied to various on-site rapid detection scenarios such as health and epidemic prevention departments, supervision departments, etc., and plays a role in rapid screening for timely and accurate judgment of whether the test object is infected with the virus.

[0019] The portable nucleic acid detection box provided by the present invention is provided with a foldable workbench inside, and a lamp post with a sterilization effect is provided above the workbench, which not only saves space but also avoids contamination between various viruses during experimental operations and during the sampling process when detecting a virus.

[0020] The portable nucleic acid detection box provided by the present invention has a foldable support structure provided at the bottom of the workbench for reinforcing and supporting the workbench, which is easy to operate. At the same time, the foldable design saves space and is simple to operate and easy to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Attached Figure 1 It is a structural schematic diagram of the present invention.

[0022] Attached Figure 2 It is a side view of the present invention.

[0023] Attached Figure 3 It is a structural schematic diagram of the support structure of the present invention.

[0024] Attached Figure 4 It is a partial structural top view of the support structure of the present invention.

[0025] Attached Figure 5 It is a partial structural front view of the supporting structure of the present invention.

[0026] Attached Figure 6 It is a structural schematic diagram of the control block of the present invention. DETAILED DESCRIPTION

[0027] The following descriptions are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention.

[0028] Example: As attached Figure 1 , 2 , 3, 4, 5 and attached Figure 6 As shown, the portable nucleic acid detection box includes a box body 1 with a plurality of troughs for placing equipment separated by vertical boards 3 and a box cover 2 hinged to the box body 1, a workbench 4 located at the upper end of the vertical board 3 is arranged in the box body 1, and two side ends of the workbench 4 are respectively hinged with two first connecting rods 51 hinged to the inner side walls of the box body 1 at both ends, and two second connecting rods 52 hinged to the inner side walls of the box cover 2 at both ends, and a support structure 9 for supporting the workbench 4 is arranged on the vertical board 3.

[0029] In this embodiment, the workbench 4 rotates to expand and retract following the rotational opening and closing action of the box cover 2. The first connecting rod 51 and the second connecting rod 52 are used to ensure the effectiveness of the basic hinge structure on the workbench 4, and the supporting structure 9 is used to ensure the stability of the workbench 4 when placing items.

[0030] The supporting structure 9 includes two supporting columns 91 arranged in the installation groove 31 opened on the surface of the vertical plate 3, and each of the supporting columns 91 is provided with a first through hole 911 at the end close to the side groove wall of the installation groove 31, and the connecting column 92 with both side ends connected to the groove wall of the installation groove 31 is provided inside. A torsion spring 93 with one end connected to the connecting column 92 and the other end connected to the inner wall of the first through hole 911 is installed in the first through hole 911.

[0031] In this embodiment, the torsion spring 93 enables the support column 91 to have a normal state, ie, a tendency, to support the workbench 4 after being rotated and unfolded.

[0032] The support structure 9 includes a limiting column 94 provided on the surface of the limiting groove 32 provided with a first limiting block 321 provided on the inner side wall of the limiting groove 32 and a limiting protrusion 941 matching the second limiting block 322, and a control block 95 connected to the limiting column 94, and the control block 95 is provided with a tension spring 96 connected to the mounting inner ring 323 provided inside the limiting groove 32. The limiting groove 32 is provided with a limiting inner ring 324 at the end of the inner groove wall different from the control block 95. The end of the second limiting block 322 close to the limiting column 94 is formed with a groove 322a adapted to the column body of the limiting column 94. The surface of the control block 95 is provided with a first mark 951 that coincides with the projection of the limiting protrusion 941. The surface of the vertical board 3 is provided with a second mark 33 corresponding to the first limiting block 321 and / or the second limiting block 322.

[0033] In this embodiment, the use method and advantages of the support structure 9 are as follows.

[0034] First, when the limiting protrusion 941 is on the first limiting block 321, the limiting column 94 is in a relatively retracted state in the mounting groove 31, so the limiting column 94 cannot clamp the supporting column 91 thereon, and the supporting column 91 can stably support the workbench 4. At this time, the portable nucleic acid detection box is in the unfolded use state.

[0035] Secondly, after the portable nucleic acid detection box is used, the support column 91 is first manually rotated to retract, and then the control block 95 is rotated so that the limiting protrusion 941 is located on the first limiting block 321. In this way, the limiting column 94 is in a relatively extended state in the installation groove 31, and the support column 91 is stably limited and fixed, and will no longer be accidentally rotated open.

[0036] A lamp post 7 is arranged on the inner wall of the box cover 2 .

[0037] In this embodiment, the lamp post 7 is arranged according to the existing installation and switching method to ensure the normal lighting function.

[0038] The lower end surface of the box body 1 at the hinged connection between the box body 1 and the box cover 2 is provided with an armrest 8 .

[0039] In this embodiment, the armrest 8 has two functions: the first is to hold and carry the detection box, and the second is to limit the maximum opening angle of the box cover 2.

[0040] A roller 6 is provided at the lower end of the box body 1 .

[0041] In this embodiment, the rollers 6 are arranged according to the prior art to ensure that the detection box can be rolled and transported on the ground.

[0042] The embodiments of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above embodiments. Various modifications can be made within the knowledge of ordinary technicians in the technical field without departing from the purpose of the present invention. These are all non-creative modifications and are protected by patent law as long as they are within the scope of the claims of the present invention.

Claims

1. A portable nucleic acid detection box, comprising a box body (1) having a plurality of slots for placing equipment separated by vertical plates (3) and a box cover (2) hinged to the box body (1), characterized in that: A workbench (4) is provided in the box body (1) and is located at the upper end of the vertical plate (3). Two first connecting rods (51) hinged to the inner side walls at both ends of the box cover (2) and two second connecting rods (52) hinged to the inner side walls at both ends of the box body (1) are respectively hingedly connected. A supporting structure (9) for supporting the workbench (4) is provided on the vertical plate (3). The support structure (9) comprises two support columns (91) arranged in a mounting groove (31) provided on the surface of the vertical plate (3); each support column (91) has an end portion close to a side groove wall of the mounting groove (31) provided with a first through hole (911) provided therein with a connecting column (92) connected at both side ends to the groove wall of the mounting groove (31); a torsion spring (93) is installed in the first through hole (911), one end of the torsion spring being connected to the connecting column (92) and the other end being connected to the inner wall of the first through hole (911); The support structure (9) comprises a limiting column (94) disposed in a limiting groove (32) provided on the vertical plate (3), the surface of which is provided with a limiting protrusion (941) matching a first limiting block (321) and a second limiting block (322) provided on the inner side wall of the limiting groove (32), and a control block (95) connected to the limiting column (94), the control block (95) being provided with a tension spring (96) connected to an inner mounting ring (323) provided inside the limiting groove (32). A lamp post (7) is provided on the inner wall of the box cover (2). The method of using the support structure (9) is as follows: When the limiting protrusion (941) is on the second limiting block (322), the limiting column (94) is in a relatively retracted state in the mounting groove (31), so that the limiting column (94) cannot get stuck on the supporting column (91), and the supporting column (91) can stably support the workbench (4). At this time, the portable nucleic acid detection box is in an unfolded use state. When the portable nucleic acid detection box is used up, the support column (91) is first manually rotated to retract, and then the control block (95) is rotated so that the limiting protrusion (941) is located on the first limiting block (321). In this way, the limiting column (94) is in a relatively extended state in the installation groove (31), and the support column (91) is limited and fixed, and will no longer be accidentally rotated open.

2. The portable nucleic acid detection box according to claim 1, characterized in that: The limiting groove (32) is different from the control block (95) in that a limiting inner ring (324) is provided at the inner groove wall end.

3. The portable nucleic acid detection box according to claim 1, characterized in that: The end of the second limiting block (322) close to the limiting column (94) is formed with a groove (322a) adapted to the body of the limiting column (94).

4. The portable nucleic acid detection box according to claim 1, characterized in that: The surface of the control block (95) is provided with a first mark (951) that coincides with the projection of the limiting protrusion (941).

5. The portable nucleic acid detection box according to claim 4, characterized in that: The surface of the vertical plate (3) is provided with a second mark (33) corresponding to the first limiting block (321) and / or the second limiting block (322).

6. The portable nucleic acid detection box according to claim 1, characterized in that: A handrail (8) is provided on the lower end surface of the box body (1) at the hinged joint between the box body (1) and the box cover (2).

7. The portable nucleic acid detection box according to claim 1, characterized in that: A roller (6) is provided at the lower end of the box body (1).

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