New molecular diagnostic testing equipment

Abstract

The present invention discloses a novel molecular diagnosis detection device, comprising: a shell, and a reaction component and a shooting component arranged at intervals along a first direction in the shell; the reaction component comprises a fixed part, a reaction part and a background plate, the fixed part is used to place a sample to be tested; the reaction part forms a reaction chamber for the sample to be tested to undergo a test reaction, and the reaction part is movably arranged relative to the fixed part; the background plate is arranged on a side of the fixed part and the reaction part away from the shooting component; wherein, when the fixed part is attached to the reaction part, the reaction chamber is sealed, and the sample to be tested placed on the fixed part is located in the reaction chamber; when the reaction part is separated from the fixed part, the sample to be tested placed on the fixed part is located between the background plate and the shooting component. The device of the present invention has a simple structure, can be tested quickly and conveniently, and is particularly suitable for molecular diagnosis.

Description

Technical Field

[0001] The invention belongs to the technical field of biological testing equipment, and in particular relates to a novel molecular diagnostic testing equipment. Background Art

[0002] Molecular diagnosis is a technology that uses molecular biology methods to detect changes in the structure or expression level of genetic material in organisms to make diagnoses. Since molecular diagnosis can be performed at the gene level, the advantages of detection sensitivity and accuracy are more obvious. It can identify viruses at the early stage of infection or confirm genetic defects early, thereby providing personalized medical diagnosis services. It is mainly used in the detection and diagnosis of genetic diseases, infectious diseases, tumors and other diseases.

[0003] With the deepening of human understanding of diseases and the technological progress of genetic testing, the global molecular diagnostic market has grown rapidly, and new molecular diagnostic technologies and their latest clinical applications have developed rapidly. Clinical diagnosis and treatment have entered the era of precision medicine, and the role of molecular diagnosis in clinical practice is becoming increasingly obvious. However, the implementation time of existing technologies is very long. In order to generate sufficient detection signals, it takes many hours or days to produce enough biological targets. Amplification steps for pathogen detection, metabolite determination, or nucleic acid sequence detection usually require expensive laboratory instruments and well-trained professionals to use the instruments. Polymerase-based polymerase chain reaction instruments require careful handling of unstable reagents and must be particularly cautious to prevent contamination between samples. And the instruments are expensive and complex. These expensive and complex technologies can hardly meet the current rapidly developing needs. Summary of the invention

[0004] The main technical problem solved by the present invention is to provide a new type of molecular diagnosis detection equipment, which has a simple structure and can quickly detect samples to be tested.

[0005] In order to solve the above technical problems, a technical solution adopted by the present invention is: to provide a new type of molecular diagnostic detection equipment, including: a shell, and a reaction component and a shooting component arranged at intervals along a first direction in the shell; the reaction component includes a fixed part, a reaction part and a background plate, the fixed part is used to place the sample to be tested; the reaction part is formed with a reaction chamber for allowing the sample to be tested to undergo a test reaction, and the reaction part is movably arranged relative to the fixed part; the background plate is arranged on a side of the fixed part and the reaction part away from the shooting component; wherein, when the fixed part is in contact with the reaction part, the reaction chamber is sealed, and the sample to be tested placed on the fixed part is located in the reaction chamber; when the reaction part is separated from the fixed part, the sample to be tested placed on the fixed part is located between the background plate and the shooting component.

[0006] Furthermore, a heating device is provided on the reaction part for heating the reaction chamber.

[0007] A connecting rod is arranged between the fixing part and the reaction part, and the reaction part and / or the fixing part are slidably arranged on the connecting rod, so that the fixing part and the reaction part can move relatively.

[0008] As a preferred solution, the connecting rod is connected to the bottom of the shell, the reaction part is located between the fixed part and the bottom of the shell, and the connecting rod is provided with a linkage device to control the reaction part to move away from or close to the fixed part.

[0009] As another preferred solution, the connecting rod is connected to the bottom of the shell, the reaction part is located between the fixing part and the bottom of the shell, and the connecting rod is provided with a linkage device to control the fixing part to move away from or close to the reaction part.

[0010] The background plate is connected to a side of the fixing portion away from the shooting assembly.

[0011] A support base is connected to a side of the reaction part away from the shooting component, and when the fixing part is in contact with the reaction part, the background plate is in contact with the support base.

[0012] Among them, a window is arranged at the top of the shell corresponding to the fixing part, and the window is used to place the sample to be tested on the fixing part.

[0013] Among them, the shooting component establishes communication with the PC and transmits the captured image information to the PC.

[0014] As a preferred solution, the shooting component is an exposable image acquisition device.

[0015] As another preferred solution, the shooting component includes an image acquisition device and an illumination light source arranged around the image acquisition device, so that the illumination light source works at least when the image acquisition device works.

[0016] Wherein, a display device is arranged on the shell, and the display device is used to display the reaction time and the real-time temperature of the reaction part.

[0017] Wherein, a power supply component is arranged on or inside the shell to supply power to the novel molecular diagnostic detection device.

[0018] The beneficial effects of the present invention are as follows: Different from the prior art, the novel molecular diagnostic detection device of the embodiment of the present invention is provided with a relatively movable fixed part and a reaction part. When the fixed part and the reaction part are attached, the sample to be tested is placed in the reaction chamber, and the sample to be tested can react in the reaction chamber. After the reaction is completed, the fixed part and the reaction part are separated, so that the sample to be tested is separated from the reaction chamber, and the image of the sample to be tested is captured by the shooting component, wherein the background plate is used as the background plate when the sample to be tested is photographed, which can ensure that the background of the sample to be tested is uniform and easy to compare, and the shooting component is combined with the background plate to collect the image of the sample to be tested; the novel molecular diagnostic detection device of the embodiment of the present invention has a simple structure, can be detected quickly and conveniently, and is suitable for detecting or monitoring trace chemical and / or biological targets present in samples at very low concentrations, including but not limited to biological samples, materials, organic or inorganic samples. It is particularly suitable for molecular diagnosis. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the novel molecular diagnostic detection device of the present invention;

[0020] Figure 2 This is a schematic diagram of the split structure of the first embodiment of the novel molecular diagnostic detection device of the present invention;

[0021] Figure 3 yes Figure 2 A schematic diagram of an embodiment of a state in which a fixing part and a reaction part are attached to each other;

[0022] Figure 4 yes Figure 2 A schematic diagram of another embodiment of the state where the fixing part and the reaction part are attached to each other;

[0023] Figure 5 This is a schematic diagram of the split structure of the second embodiment of the novel molecular diagnostic detection device of the present invention;

[0024] Figure 6 yes Figure 5 A schematic diagram of an embodiment of a state in which the fixing part and the reaction part are separated;

[0025] Figure 7 This is a schematic diagram of the disassembly structure of the third embodiment of the novel molecular diagnostic detection device of the present invention;

[0026] Figure 8 yes Figure 7 A schematic diagram of an embodiment of a state in which a fixing part and a reaction part are attached to each other;

[0027] Fig. 9 yes Figure 7 A schematic diagram of another embodiment of the state where the fixing part and the reaction part are attached to each other;

[0028] Fig.10 yes Figure 7 A schematic diagram of another embodiment of the state in which the fixing part and the reaction part are bonded together. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solution and effect of the present invention clearer and more specific, the present invention is further described in detail below with reference to the accompanying drawings and examples.

[0030] The present invention provides a novel molecular diagnostic detection device. Figure 1-3 As shown, it includes: a shell 1, and a reaction component 2 and a shooting component 3 arranged at intervals along a first direction D1 in the shell 1; the reaction component 2 includes a fixing part 21, a reaction part 23 and a background plate 22, the fixing part 21 is used to place the sample to be tested; the reaction part 23 is formed with a reaction chamber 231 for allowing the sample to be tested to undergo a test reaction, and the reaction part 23 is movably arranged relative to the fixing part 21; the background plate 22 is arranged on a side of the fixing part 21 and the reaction part 23 away from the shooting component 3; wherein, when the fixing part 21 and the reaction part 23 are attached to each other, the reaction chamber 231 is sealed, and the sample to be tested placed on the fixing part 21 is located in the reaction chamber 231; when the reaction part 23 is separated from the fixing part 21, the sample to be tested placed on the fixing part 21 is located between the background plate 22 and the shooting component 3.

[0031] In the embodiment of the present invention, the “first direction D1 ” refers to a direction perpendicular to the background plate 22 .

[0032] The novel molecular diagnostic detection device in the embodiment of the present invention is provided with a relatively movable fixed part 21 and a reaction part 23. When the fixed part 21 and the reaction part 23 are in contact with each other, the sample to be tested is placed in the reaction chamber 231. At this time, the sample to be tested can react in the reaction chamber 231. After the reaction is completed, the fixed part 21 and the reaction part 23 are separated so that the sample to be tested is separated from the reaction chamber 231. The image of the sample to be tested is captured by the shooting component 3, wherein the background plate 22 is used as the background plate 22 when the sample to be tested is photographed, which can ensure that the background of the sample to be tested is uniform and easy to compare, and the shooting component 3 is combined with the background plate 22 to capture the image of the sample to be tested.

[0033] Furthermore, a heating device (not shown) is provided on the reaction part 23 for heating the reaction chamber 231. In the embodiment of the present invention, the heating device is provided at the bottom of the reaction part 23, and in other embodiments, the heating device may also be provided on one side of the reaction part 23 or around the reaction part 23. By providing the heating device in the embodiment of the present invention, the reaction chamber 231 can maintain a stable temperature, and the temperature is adjustable.

[0034] Specifically, the housing 1 of the embodiment of the present invention includes a housing bottom 11 and an upper housing 12 disposed on the housing bottom 11, wherein the housing bottom 11 and the upper housing 12 are detachably disposed to facilitate detection and maintenance of the device, wherein, in order to improve the sealing performance of the housing 1, a sealing ring (not shown) may also be disposed at the connection between the housing bottom 11 and the upper housing 12. Of course, in other embodiments, the housing bottom 11 and the upper housing 12 may also be non-detachable, so that the sealing and fixing effect thereof is better.

[0035] A connecting rod 25 is provided between the fixing part 21 and the reaction part 23, and the reaction part 23 and / or the fixing part 21 are slidably provided on the connecting rod 25, so that the fixing part 21 and the reaction part 23 can move relative to each other. In the embodiment of the present invention, by providing the connecting rod 25, the fixing part 21 can be moved (see Figure 4 ), or move the reaction unit 23 (see Figure 3 ), or the fixing part 21 and the reaction part 23 are moved simultaneously to achieve the purpose of separating or bonding the fixing part 21 and the reaction part 23.

[0036] In one embodiment of the present invention, Figure 2 and 4As shown, a connecting rod 25 is arranged between the fixing part 21 and the reaction part 23, wherein the connecting rod 25 is a telescopic rod, the fixing part 21 and the reaction part 23 are arranged up and down, and the reaction part 23 is placed on the bottom 11 of the shell body, and the fixing part 21 can be driven to move upward or downward by the telescopic movement of the connecting rod 25. Specifically, in the embodiment of the present invention, the fixing part 21 includes a planar plate body, and a plurality of through holes are arranged on the planar plate body in sequence along the second direction D2 perpendicular to the first direction D1, and the through holes can be used to place and fix the test tube 6 of the sample to be tested; when the fixing part 21 contacts the reaction part 23, the through holes correspond to the reaction chamber 231, and the through holes and the reaction chamber 231 can be seamlessly connected. In the embodiment of the present invention, the background plate 22 is adjacent to the fixing part 21, the background plate 22 is arranged along the second direction D2, and the distance between the through holes and the background plate 22 is such that when taking pictures, the test tube 6 in the through holes has no projection on the background plate 22, so as to ensure that when the shooting component 3 takes pictures, there will be no projection affecting the shooting result. Specifically, in the embodiment of the present invention, the background plate 22 is fixed and does not move with the movement of the fixing part 21. It is only necessary to ensure that the background plate 22 has a sufficient height so that when the fixing part 21 moves upward, the orthographic projection of the test sample in the test tube 6 on the fixing part 21 can fall on the background plate 22. In other embodiments, the background plate 22 can also move with the movement of the fixing part 21, so that the orthographic projection of the test sample in the test tube 6 on the fixing part 21 can fall on the background plate 22. At this time, when the fixing part 21 is attached to the reaction part 23, the height of the background plate 22 can not exceed the fixing part 21, so that when the sample to be tested is placed, it is not easy to touch the background plate 22. In other embodiments, the connecting rod 25 can also be a fixing rod, and the fixing part 21 or the reflection part 23 can slide on the connecting rod 25, so that the fixing part 21 or the reflection part 23 moves up and down, so that the fixing part 21 and the reaction part 23 are attached or separated.

[0037] As a preferred embodiment of the present invention, continue as follows Figure 1-4As shown, the connecting rod 25 is connected to the bottom 11 of the shell, and the reaction part 23 is located between the fixed part 21 and the bottom 11 of the shell. The connecting rod 25 is provided with a linkage device (not shown) to control the reaction part 23 to move away from or close to the fixed part 21. By connecting the connecting rod 25 to the bottom 11 of the shell, the fixed part 21 and the reaction part 23 can be combined with the bottom 11 of the shell, so as to avoid the fixed part 21 and the reaction part 23 from shaking in the shell 1 to affect the test results. At the same time, it can also ensure that there is no deviation in the position between the fixed part 21 and the reaction chamber 231 during the process of the reaction part 23 moving away from or close to the fixed part 21. In the embodiment of the present invention, the connecting rod 25 is provided with a linkage device, and the connecting rod 25 can be telescopically moved by providing the linkage device to move the reaction part 23, so as to ensure that the reaction part 23 can move away from or close to the fixed part 21, and by providing the linkage device, the degree of automation of the movement of the reaction part 23 can be enhanced. In the embodiment of the present invention, when the fixing part 21 and the reaction part 23 are attached to each other, there is a certain distance between the reaction part 23 and the bottom 11 of the shell body to ensure that the reaction part 23 can be away from the fixing part 21; by moving the reaction part 23, the fixing part 21 and the sample to be tested located in the fixing part 21 can be fixed in a fixed state, so as to adjust and set other parameters such as the position, height and shooting angle of the shooting component 3. At the same time, the sample to be tested does not move, which can avoid the shaking of the sample to be tested and affect the image captured by the shooting component 3.

[0038] In another embodiment, the linkage device can control the fixed part 21 to move away from or close to the reaction part 23. At this time, the connecting rod 25 fixes the reaction part 23 to the bottom 11 of the housing, and the connecting rod 25 is connected between the fixed part 21 and the reaction part 23. By setting the linkage device, the fixed part 21 can be controlled to move so that the fixed part 21 is away from the reaction part 23, or the fixed part 21 moves toward the reaction part 23 and fits the reaction part 23, so that the sample to be tested is placed in the reaction chamber 231 or separated from the reaction chamber 231. When the fixed part 21 moves, the height of the shooting component 3 can be adjusted so that the shooting component 3 moves accordingly with the movement of the fixed part 21. In other embodiments, when the fixed part 21 moves away from the reaction part 23, the fixed part 21 moves to a certain fixed position and no longer moves. The setting height of the shooting component 3 is set with reference to when the fixed part 21 moves to the fixed position, so that when the fixed part 21 moves, the shooting component 3 can be fixed, so as to facilitate the adjustment test.

[0039] Preferably, if Figure 5 and 6As shown, the background plate 22 is connected to the side of the fixing part 21 away from the shooting component 3. In the embodiment of the present invention, the background plate 22 and the fixing part 21 are integrally formed. When the background plate 22 and the fixing part 21 are integrally formed, it can be ensured that the through holes of the background plate 22 and the fixing part 21 are adjacent to each other, and it can be ensured that when the shooting component 3 takes a picture of the sample to be tested, no shadow is formed on the background plate 22. It can be avoided that the sample to be tested is far away from the background plate 22, and the sample to be tested forms a shadow on the background plate 22, which affects the test result. In another embodiment, the background plate 22 and the fixing part 21 are manufactured and formed separately, and an integral structure is formed by connecting the background plate 22 and the fixing part 21 by welding or bonding.

[0040] More preferably, if Figure 7 As shown, the side of the reaction part 23 away from the shooting component 3 is connected to the support seat 24, and when the fixing part 21 is in contact with the reaction part 23, the background plate 22 is in contact with the support seat 24. In the embodiment of the present invention, the reaction part 23 and the support seat 24 are integrally formed, and the background plate 22 is in contact with the support seat 24, which facilitates the contact between the background plate 22 and the reaction part 23. More preferably, the side of the background plate 22 facing the shooting component is in contact with the reaction part 23, so that the background plate 22 and the reaction part 23 are more closely in contact, and a seamless connection is achieved.

[0041] Specifically, in the embodiment of the present invention, the connecting rod 25 includes a first connecting rod 251 and a second connecting rod 252, and the first connecting rod 251 and the second connecting rod 252 are both connected between the fixing portion 21 and the reaction portion 23, wherein the first connecting rod 251 is connected between the background plate 22 and the support seat 24, and is fixed to the bottom 11 of the shell; the second connecting rod 252 is connected between the fixing portion 21 and the reaction portion 23, and is fixed to the bottom 11 of the shell; wherein the first connecting rod 251 and the second connecting rod 252 are both provided with a linkage device, so that the first connecting rod 251 and the second connecting rod 252 can be telescopically moved, so that the fixing portion 21 and the reaction portion 23 are fitted together, as shown in FIG. Figure 7 and 8 As shown, by moving the reaction parts 23 to make them fit together; Figure 7 and 9As shown, the fixing part 21 is moved to make them fit each other, and the two sides of the background plate 22 are respectively fitted with the support seat 24 and the reaction part 23. In the embodiment of the present invention, by setting the first connecting rod 251 and the second connecting rod 252, it can be ensured that the contact surfaces between the background plate 22, the support seat 24, the fixing part 21 and the reaction part 23 are in close contact, and seamless contact is achieved. In the embodiment of the present invention, the background plate 22, the support seat 24, the fixing part 21 and the reaction part 23 are all made of aluminum. The reaction part 23 is heated. Since the material is aluminum, its heat conductivity is relatively good. When the reaction part 23 is in close contact with the fixing part 21, the heat of the reaction part 23 is easily transferred to the fixing part 21, so that the temperature consistency of the reaction part 23 and the fixing part 21 is strong, and the sample to be tested is heated evenly. If there is a gap between the fixed part 21 and the reaction part 23, the heat transfer between the fixed part 21 and the reaction part 23 needs to be carried out through the atmosphere, and the heat transfer effect is poor. There is a temperature difference between the reaction part 23 and the fixed part 21. When the temperature of the reaction part 23 is higher than the temperature of the fixed part 21, it may cause uneven reaction of the sample to be tested, or the sample to be tested may be cooled and crystallized at the position of the fixed part 21 after the reaction, affecting the test result. In the embodiment of the present invention, by providing the first connecting rod 251 and the second connecting rod 252, the background plate 22, the support seat 24, the fixed part 21 and the reaction part 23 can be in close contact, and a seamless connection can be achieved to ensure the accuracy of the experimental test. In other embodiments, the material of the background plate 22, the support seat 24, the fixed part 21 and the reaction part 23 can also be other metal materials or other heat transfer and heat insulation materials.

[0042] In another embodiment, if Figure 7 and Fig.10 The first connecting rod 251 and the second connecting rod 252 can be fixed to the bottom 11 of the shell body, and the other one is only connected between the fixing part 21 and the reaction part 23, or the other one is only connected between the background plate 22 and the support seat 24. Specifically, the first connecting rod 251 is connected between the background plate 22 and the support seat 24, and is fixed to the bottom 11 of the shell body; the second connecting rod 252 is connected between the fixing part 21 and the reaction part 23, wherein the first connecting rod 251 and the second connecting rod 252 can be telescopically moved by the linkage device to drive the fitting and separation between the background plate 22 and the support seat 24, and the fixing part 21 and the reaction part 23; in other embodiments, the linkage device drives the second connecting rod 252 to move telescopically to drive the fitting and separation between the fixing part 21 and the reaction part 23, and at the same time, the background plate 22 or the support seat 24 slides on the first connecting rod 251 to drive the fitting or separation between the background plate 22 and the support seat 24.

[0043] Among them, a window 13 is provided at the top of the housing 1 corresponding to the fixing portion 21, and the window 13 is used to place the sample to be tested on the fixing portion 21. As a preference, a cover plate is provided at the window 13. When placing the sample to be tested, the cover plate is opened and the sample to be tested is placed from the window 13, so that the sample placement is convenient and it can be ensured that the sample to be tested is not affected by the atmosphere outside the housing 1, avoiding other cross-influences. In other embodiments, the cover plate may not be provided.

[0044] Among them, the shooting component 3 establishes communication with the PC end, and transmits the captured image information to the PC end. In the embodiment of the present invention, by establishing a communication connection between the shooting component 3 and the PC end, the image of the sample to be tested captured by the shooting component 3 can be transmitted to the PC end in real time, and the image is processed and calculated by the PC end. In the embodiment of the present invention, the shooting component 3 is connected to the PC end through a signal line. In other embodiments, the shooting component 3 can also be connected to the PC end through wireless signal transmission, or through a mobile medium, such as a card reader or a U disk, etc., to transmit the image captured by the shooting component 3 to the PC end through a USB interface.

[0045] The space formed by the fixed part 21, the background plate 22 and the shooting component 3 in the shell 1 is a dark space, so that the shooting component 3 is not affected by the surrounding external light when taking pictures of the sample to be tested, and the external interference factors are eliminated. As a preferred solution, the shooting component 3 is an exposable image acquisition device, so that the sample to be tested can be photographed in the dark. As another preferred solution, the shooting component 3 includes an image acquisition device 31, and an illumination light source 32 arranged around the image acquisition device 31, so that the illumination light source 32 works at least when the image acquisition device 31 works. When the fixed part 21 is separated from the reaction part 23, the illumination light source 32 is illuminated when the sample to be tested needs to be photographed, so that the image acquisition device 31 can perform image acquisition such as taking pictures. Among them, the image acquisition device 31 in the embodiment of the present invention is a microscopic image acquisition device. Further, in order to save energy, the illumination light source 32 only works when the image acquisition device 31 performs image acquisition, and a control circuit can be set, and an illumination switch 5 is set on the shell 1 to control the operation and stop of the illumination light source 32.

[0046] The housing 1 is provided with a display device 4, which is used to display the reaction time and the real-time temperature of the reaction part 23. The display device 4 is embedded in the housing 1 so as to monitor the reaction time and the real-time temperature of the reaction. In the embodiment of the present invention, the display device 4 is arranged on the top of the housing 1. In other embodiments, the display device 4 may also be arranged on the side of the housing 1. A temperature detection device (not shown) is arranged in the housing 1 to detect the temperature of the reaction part 23. The display device 4 is connected to the temperature detection device to display the real-time temperature of the reaction part 23.

[0047] Furthermore, a power supply component is provided on or in the shell 1 to supply power to the novel molecular diagnostic detection equipment. Specifically, in an embodiment of the present invention, a power supply component is provided in the shell 1, and the power supply component is a storage battery or a dry cell battery. The power supply component supplies power to the heating device and the illumination light source 32, so that the heating device is an electric heating device, and the illumination light source 32 can work. The power supply component can also supply power to other components, such as the display device 4. In an embodiment of the present invention, the power supply component is provided below the shooting component 3. In other embodiments, the power supply component can also be provided at the bottom 11 of the shell, and the embodiment of the present invention does not specifically limit the setting position. By supplying power to the novel molecular diagnostic detection equipment with a storage battery or a dry cell battery, the novel molecular diagnostic detection equipment can be easily carried outdoors for detection, and can also be used as a backup power supply to ensure that the novel molecular diagnostic detection equipment is in a working state.

[0048] The housing 1 may also be provided with a power supply port 7, which is connected to AC or DC via a power supply line, so that the novel molecular diagnostic detection device can be powered by AC or DC, to facilitate the needs of users.

[0049] The novel molecular diagnostic detection device of the embodiment of the present invention has a simple structure, is easy to carry, can perform detection quickly and conveniently, and is suitable for detecting or monitoring trace chemical and / or biological targets present in very low concentrations in samples, including but not limited to biological samples, materials, organic or inorganic samples. It is particularly suitable for molecular diagnosis.

[0050] In the embodiment of the present invention, Figure 1 , Figure 7 and Figure 8 The novel molecular diagnostic detection device shown in the figure takes it as an example, and its working process is as follows: the sample to be tested and the reagent are added to the test tube 6. In the embodiment of the present invention, the test tube 6 is a serum tube, which is placed in the fixed part 21 through the window 13 on the upper shell 12. The connecting rod 25 drives the reaction part 23 to rise through the linkage device, and is tightly combined with the fixed part 21 to form a closed reaction chamber 231 for the sample to be tested and the reagent in the serum tube to react inside. At this time, the heating device is controlled to heat the reaction chamber 231 so that the reaction chamber 231 is in a constant temperature state. After the heating time is over, the reaction part 23 is controlled to descend to the bottom 11 of the shell through the linkage device, and the serum tube is exposed from the reaction chamber 231. Turn on the lighting switch 5 on the shell 1, and the lighting source 32 works to emit light. The image acquisition software on the PC side controls the image acquisition device 31 to acquire images, and the heating reaction and image acquisition process are completed at this time.

[0051] The above description is only an implementation mode of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the present invention specification and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A novel molecular diagnostic detection device, characterized in that: include: A housing (1), and a reaction component (2) and a shooting component (3) arranged in the housing (1) at intervals along a first direction (D1); the reaction component (2) comprises: A fixing portion (21) for placing a sample to be tested; The reaction part (23) is formed with a reaction chamber (231) for causing the sample to be tested to undergo a test reaction, and the reaction part (23) is movably arranged relative to the fixed part (21); a connecting rod (25) is arranged between the fixed part (21) and the reaction part (23), and the reaction part (23) and / or the fixed part (21) are slidably arranged on the connecting rod (25), so that the fixed part (21) and the reaction part (23) can move relative to each other; A background plate (22) is arranged on a side of the fixing portion (21) and the reaction portion (23) away from the shooting component (3); When the fixing part (21) and the reaction part (23) are attached to each other, the reaction chamber (231) is sealed, and the sample to be tested placed on the fixing part (21) is located in the reaction chamber (231); when the reaction part (23) and the fixing part (21) are separated, the sample to be tested placed on the fixing part (21) is located between the background plate (22) and the shooting component (3).

2. The novel molecular diagnostic detection device according to claim 1, characterized in that: The reaction part (23) is provided with a heating device for heating the reaction chamber (231).

3. The novel molecular diagnostic detection device according to claim 1, characterized in that: The connecting rod (25) is connected to the bottom (11) of the shell, the reaction part (23) is located between the fixed part (21) and the bottom (11) of the shell, and the connecting rod (25) is provided with a linkage device to control the reaction part (23) to move away from or close to the fixed part (21).

4. The novel molecular diagnostic detection device according to claim 3, characterized in that: The connecting rod (25) is connected to the bottom (11) of the shell, the reaction part (23) is located between the fixed part (21) and the bottom (11) of the shell, and the connecting rod (25) is provided with a linkage device to control the fixed part (21) to move away from or close to the reaction part (23).

5. The novel molecular diagnostic detection device according to claim 1, characterized in that: The background plate (22) is connected to a side of the fixing portion (21) away from the shooting assembly (3).

6. The novel molecular diagnostic detection device according to claim 5, characterized in that: A support seat (24) is connected to a side of the reaction portion (23) away from the shooting assembly (3); when the fixing portion (21) is in contact with the reaction portion (23), the background plate (22) is in contact with the support seat (24).

7. The novel molecular diagnostic detection device according to claim 1, characterized in that: A window (13) is provided at the top of the housing (1) corresponding to the fixing portion (21), and the window (13) is used to place the sample to be tested on the fixing portion (21).

8. The novel molecular diagnostic detection device according to claim 1, characterized in that: The shooting component (3) establishes communication with the PC and transmits the captured image information to the PC; The shooting component (3) is an exposure type image acquisition device, or The shooting component (3) comprises an image acquisition device (31) and an illumination light source (32) arranged around the image acquisition device (31), so that the illumination light source (32) works at least when the image acquisition device (31) works.

9. The novel molecular diagnostic detection device according to claim 1, characterized in that: A display device (4) is arranged on the shell (1), and the display device (4) is used to display the reaction time and the real-time temperature of the reaction part (23); a power supply component is arranged on or inside the shell (1), and is used to supply power to the novel molecular diagnostic detection device.

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