Dual-mode OCTA imaging optical system

Abstract

The present invention discloses an OCTA imaging optical path system with dual working modes. The OCTA imaging optical path system includes a reference arm optical path and at least two sample arm optical paths that cooperate with a light source and a coupler. The coupler is at least used to divide the source light beam emitted by the light source into a first sub-beam and a second sub-beam. The first sub-beam and the second sub-beam correspond to the input reference arm optical path and the sample arm optical path, respectively. An embodiment of the present invention provides an OCTA imaging optical path system with dual working modes, which has two sample arm optical paths with different working modes. The two sample arm optical paths cooperate with one reference arm optical path to realize the switching of different working modes of the OCTA sample arm optical path, so that a single device has two different usage modes and can be switched at will between a fixed data acquisition mode and a handheld data acquisition mode, which greatly improves the efficiency and performance of the device, thereby meeting the needs of different types of patients and greatly saving the cost of the device.

Description

Technical Field

[0001] The present invention relates to an OCTA imaging optical path system, in particular to an OCTA imaging optical path system with dual working modes, and belongs to the technical field of optical coherence tomography. Background Art

[0002] Optical coherence tomography (OCTA) is a non-invasive imaging method based on the constant flow of blood cells in fundus vessels. OCTA uses coherent optical tomography to image cross-sectional structures at micrometer-scale resolution. Using specialized computer image processing algorithms, these moving blood cells, or blood flow signals, are obtained. These vascular structure signals are then used for three-dimensional reconstruction, presenting fundus vascular images layer by layer in a coronal plane (en face) format, thereby obtaining images of the various fundus tissue structures. This unique feature of OCTA has applications in the diagnosis and treatment of various fundus diseases, including retinal vascular diseases, glaucoma, idiopathic juxtafoveal telangiectasia, diabetic retinopathy, choroidal neovascularization, and optic neuritis.

[0003] Currently, most commercial ophthalmic OCTA devices on the market collect data in a single, fixed-tablet mode. These devices can meet clinical needs for general ophthalmology patients, for example, within this single patient population. However, when treating both general patients and special populations such as those undergoing anesthesia, critically ill bedridden patients, premature infants with retinopathy, and infants, additional OCTA examination equipment is required. However, multiple OCTA imaging devices not only take up space and increase equipment purchase and maintenance costs, but also increase equipment costs. Summary of the Invention

[0004] The main purpose of the present invention is to provide an OCTA imaging optical path system with dual working modes to overcome the deficiencies in the prior art.

[0005] To achieve the aforementioned object of the invention, the technical solutions adopted by the present invention include:

[0006] A typical embodiment of the present invention provides a dual-mode OCTA imaging optical path system, comprising a reference arm optical path and at least two sample arm optical paths, which cooperate with a light source and a coupler. The coupler is at least configured to split a source light beam emitted by the light source into a first sub-beam and a second sub-beam, wherein the first sub-beam and the second sub-beam correspond to inputs into the reference arm optical path and the sample arm optical path, respectively.

[0007] When one of the sample arm optical paths works in conjunction with the reference arm optical path, the OCTA imaging optical path system can realize a fixed acquisition mode, and when the other sample arm optical path works in conjunction with the reference arm optical path, the OCTA imaging optical path system can realize a handheld acquisition mode.

[0008] Compared with the prior art, the advantages of the present invention include: the embodiment of the present invention provides a dual-working mode OCTA imaging optical path system, which has two sample arm optical paths with different working modes. The two sample arm optical paths cooperate with a reference arm optical path to realize the switching of different working modes of the OCTA sample arm optical path, so that a single device has two different usage modes and can be switched freely between a fixed data acquisition mode and a handheld data acquisition mode, greatly improving the efficiency and performance of the device, thereby meeting the needs of different types of patients and greatly saving equipment costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0009] Figure 1 This is a schematic structural diagram of a dual-working mode OCTA imaging optical path system provided in a typical embodiment of the present invention;

[0010] Figure 2 It is a structural schematic diagram of a fixed-mounted sample arm optical path or a handheld sample arm optical path provided in a typical embodiment of the present invention. DETAILED DESCRIPTION

[0011] In view of the shortcomings of the prior art, the inventors of this case, after long-term research and extensive practice, have proposed the technical solution of the present invention. The following will further explain this technical solution, its implementation process and principles.

[0012] An embodiment of the present invention provides a multi-working mode OCTA imaging system based on optical coherence tomography imaging, including a reference arm and two sample arms. The two sample arms share a reference arm, which allows for convenient and quick switching between sample arms with two different working modes, allowing a single device to simultaneously have two different working modes, such as a fixed acquisition mode and a handheld acquisition mode.

[0013] An embodiment of the present invention provides a dual-mode OCTA imaging optical path system, comprising a reference arm optical path and at least two sample arm optical paths that cooperate with a light source and a coupler. The coupler is at least configured to split a source light beam emitted by the light source into a first sub-beam and a second sub-beam. The first sub-beam and the second sub-beam correspond to inputs into the reference arm optical path and the sample arm optical path, respectively.

[0014] When one of the sample arm optical paths works in conjunction with the reference arm optical path, the OCTA imaging optical path system can realize a fixed acquisition mode, and when the other sample arm optical path works in conjunction with the reference arm optical path, the OCTA imaging optical path system can realize a handheld acquisition mode.

[0015] Furthermore, the at least two sample arm optical paths are connected to the coupler via an optical switch. By switching the optical switch, the second split light beam can be input into a designated sample arm optical path, thereby enabling the designated sample optical path to cooperate with the reference arm optical path and realize a handheld collection mode or a fixed collection mode.

[0016] Furthermore, the reference arm optical path includes a third collimator, an aperture and a reflector, and the first sub-beam output from the coupler passes through the collimator and the aperture in sequence before reaching the reflector.

[0017] Furthermore, the at least two sample arm optical paths include at least one fixed sample arm optical path and at least one handheld sample arm optical path, the fixed sample arm optical path and the handheld sample arm optical path are arranged in parallel, and the fixed sample arm optical path and the handheld sample arm optical path cannot work at the same time.

[0018] Furthermore, the fixed-mounted sample arm optical path includes a first collimator, a first scanning galvanometer, a first lens and a second lens. The second sub-beam passes through the first collimator and is incident on the first scanning galvanometer. The outgoing light of the first scanning galvanometer passes through the first lens and the second lens in sequence and is incident on the human eye.

[0019] Furthermore, the fixed-mounted sample arm optical path includes a second collimator, a second scanning galvanometer, a second lens and a second lens. The second split light beam passes through the second collimator and is incident on the second scanning galvanometer. The outgoing light of the second scanning galvanometer passes through the second lens and the second lens in sequence and is incident on the human eye.

[0020] Furthermore, the dual-working mode OCTA imaging optical path system includes a sample arm and a reference arm, the sample arm includes a fixed-mounted sample arm optical path, a handheld sample arm optical path and an optical switch, the coupler is connected to the fixed-mounted sample arm optical path and the handheld sample arm optical path via the optical switch, and the reference arm includes a reference arm optical path.

[0021] Furthermore, the source beam is split into a first sub-beam and a second sub-beam in a ratio of 3:1.

[0022] Furthermore, the dual-working mode OCTA imaging optical path system also includes: a light source, a coupler and an image acquisition mechanism, the light source and the image acquisition mechanism are respectively connected to the coupler, the coupler is connected to the sample arm optical path and the reference arm optical path, and the image acquisition mechanism is at least used to collect the light beam reflected by the reference arm optical path.

[0023] Furthermore, the image acquisition mechanism includes a CCD high-speed camera.

[0024] Furthermore, the light source includes a low-coherence broadband light source, and the wavelength of the low-coherence broadband light source is 850 nm and the power is 15 mW.

[0025] The technical solution, its implementation process and principles will be further explained below with reference to the accompanying drawings. Unless otherwise specified, the various components used in the embodiments of the present invention can be those known to those skilled in the art and can be purchased commercially.

[0026] An embodiment of the present invention provides a dual-mode OCTA imaging optical path system with switchable operating modes. The OCTA imaging optical path system includes a low-coherence broadband light source, a high-speed camera, a fiber coupler, a reference arm optical path, and a dual-mode sample arm optical path. The low-coherence broadband light source can be a laser light source with a wavelength of 850 nm and a power of 15 mW. The high-speed camera can be a CCD high-speed camera with a frequency of 250 kHz. The fiber coupler can be a 75:25 2*2 broadband coupler. The fiber coupler can split the source light beam emitted by the low-coherence broadband light source into two beams, with 75% of the beam (i.e., the aforementioned first beam) entering the reference arm optical path and 25% of the beam (i.e., the aforementioned second beam) entering the dual-mode sample arm optical path.

[0027] Specifically, the reference arm optical path includes a collimator, an aperture and a reflector. The first light beam is output from the coupler and enters the collimator, then passes through the aperture and reaches the reflector. The aperture can adjust the light flux so that the light entering the reflector can be adjusted according to experimental needs to meet detection requirements.

[0028] Specifically, the dual-working mode sample arm optical path includes an optical switch, a fixed-mounted sample arm optical path, and a handheld sample arm optical path.

[0029] Specifically, the optical switch is a 1*2 electrically controlled optical switch, which is electronically driven and controlled by a voltage signal, and can arbitrarily switch the optical signal from one end of the fixed sample arm optical path to one end of the handheld sample arm optical path.

[0030] Specifically, the fixed-mounted sample arm optical path includes a laser collimator, a scanning galvanometer, a lens, and an eyepiece lens. The second light beam is collimated by the laser collimator and then reflected by the two-dimensional scanning galvanometer into the lens, and then enters the eyepiece lens. After being magnified by the eyepiece lens, it enters the human eyeball; the fixed-mounted sample arm optical path can be fixedly installed on a lifting platform of ophthalmic equipment, or on an adjustment platform of other types of ophthalmic equipment. Ordinary ophthalmic patients can sit quietly in front of the fixed-mounted sample arm optical path, and the fixed-mounted sample arm optical path can be used to complete the detection.

[0031] Specifically, the handheld sample arm optical path includes a laser collimator, a scanning galvanometer, a lens, and an eyepiece lens. The second light beam is collimated by the laser collimator and then reflected by the two-dimensional scanning galvanometer into the lens, and then enters the eyepiece lens. After being magnified by the eyepiece lens, it enters the human eyeball; the handheld sample arm optical path can be set in a small box that is easy to hold in the hand. The operator's handheld device can complete detection at any angle and direction, and can enable special groups of patients such as anesthesia, bedridden critically ill patients, premature babies with retinal disease, infants and young children to maintain the most comfortable posture. The operator can complete the detection of the patient by holding the handheld sample arm optical path box.

[0032] Specifically, the scanning galvanometer is a two-dimensional mechanical scanning galvanometer, the eyepiece lens is an achromatic doublet lens with f=30, and the lens is an achromatic doublet lens with f=50.

[0033] See also Figure 1 A dual-mode OCTA imaging optical path system 100 includes a high-speed CCD camera 101, a low-coherence broadband light source 102, a 90:10 2*2 fiber coupler 103, a reference arm 200, and a sample arm 300. The reference arm 200 includes a collimator 201, an aperture 202, and a reflector 203. The sample arm 300 includes a 1*2 electrically controlled optical switch 310, a fixed-mounted sample arm optical path 320, and a handheld sample arm optical path 330. The 1*2 electrically controlled optical switch 310 is driven by an electrical signal so that the connector P of the 1*2 electrically controlled optical switch 310 is connected to the P1 connector or the P2 connector, thereby controlling the light beam output from the 2*2 fiber coupler 103 to enter the fixed-mounted sample arm optical path 302 or the handheld sample arm optical path 303.

[0034] See also Figure 2 , Figure 2 This is a structural diagram of the optical path of a fixed or handheld sample arm. The light beam is collimated by the laser collimator 301, reflected by the two-dimensional scanning galvanometer 302, and enters the lens 303. Then, it enters the eyepiece lens 304, and enters the eyeball 305 after being magnified by the eyepiece lens 304.

[0035] Specifically, the fixed-mounted sample arm optical path 302 can be installed on a lifting platform of an ophthalmic device, or on an adjustment platform of other types of ophthalmic devices. The handheld sample arm optical path 303 can be set in a small box that is convenient for handholding, or can be integrated and installed on a device such as a handheld gimbal stabilizer.

[0036] For details, please refer to Figure 1 The low-coherence broadband light source 102 emits a laser b, which is divided into two beams, a beam c and a beam d, each accounting for 75% and 25% respectively, by the 75:25 2*2 fiber coupler 103. The beam c is collimated by the collimator 201 and passes through the aperture 202. Then, it enters the reflector 203 and reflects the beam c back. The beam c returns to the 2*2 fiber coupler 103 along the original path. The beam d enters the P connector on the 1*2 electric switch 310. When ordinary ophthalmology patients need to be tested, the 1*2 The connector P of the electric switch 310 is connected to the connector P1, and the light beam d enters the fixed-mounted sample arm optical path 320. After reaching the eyeball of the subject through the fixed-mounted sample arm optical path 320, the light beam d is scattered and returns along the original optical path to the 2*2 fiber coupler 103. Together with the reflected light beam c, it is merged through the 75:25 2*2 fiber coupler 103 to form an interference light beam a. Thereafter, the interference light beam a is detected by the high-speed CCD camera 101, which converts the optical signal into an electrical signal, which is then processed by a computer to form an OCTA acquisition image.

[0037] When patients in special groups such as anesthesia, critically ill bedridden patients, premature infants with retinal disease, infants, and young children need to be tested, the 1*2 electric switch 310 connector P is connected to the P2 connector, and the light beam enters the handheld sample arm optical path 330. After passing through the handheld sample arm optical path 303 and reaching the eyeball of the person being tested, the light beam is scattered and returns, and together with the reflected light beam c, it is merged through the 75:25 2*2 optical fiber coupler 103 to form an interference light beam a. The interference light beam a is then detected by the high-speed CCD camera 101, and the high-speed CCD camera 101 converts the optical signal into an electrical signal, which is then processed by a computer to form an OCTA acquisition image.

[0038] An embodiment of the present invention provides a dual-working mode OCTA imaging optical path system, which has two sample arm optical paths with different working modes. The two sample arm optical paths cooperate with a reference arm optical path to realize switching between different working modes of the OCTA sample arm optical path, so that a single device has two different usage modes and can be switched freely between a fixed data acquisition mode and a handheld data acquisition mode, greatly improving the efficiency and performance of the device, thereby meeting the needs of different types of patients and greatly saving equipment costs.

[0039] It should be understood that the above embodiments are merely illustrative of the technical concepts and features of the present invention. Their purpose is to enable those skilled in the art to understand the contents of the present invention and implement them accordingly. They are not intended to limit the scope of protection of the present invention. Any equivalent variations or modifications made in accordance with the spirit and substance of the present invention are intended to be encompassed within the scope of protection of the present invention.

Claims

1. A dual-mode OCTA imaging optical system, characterized by It includes a reference arm optical path and at least two sample arm optical paths that cooperate with a light source and a coupler, wherein the coupler is at least used to split a source light beam emitted by the light source into a first sub-beam and a second sub-beam, wherein the first sub-beam and the second sub-beam correspond to inputs into the reference arm optical path and the sample arm optical path respectively; When one of the sample arm optical paths cooperates with the reference arm optical path, the OCTA imaging optical path system can realize a fixed acquisition mode, and when the other sample arm optical path cooperates with the reference arm optical path, the OCTA imaging optical path system can realize a handheld acquisition mode; The at least two sample arm optical paths are connected to the coupler via an optical switch, the at least two sample arm optical paths include at least one fixed sample arm optical path and at least one handheld sample arm optical path, the fixed sample arm optical path and the handheld sample arm optical path are arranged in parallel, and the fixed sample arm optical path and the handheld sample arm optical path cannot operate at the same time; The optical switch can be controlled by a voltage signal to switch the second split light beam from the fixed sample arm optical path to the handheld sample arm optical path, or to switch the second split light beam from the handheld sample arm optical path to the fixed sample arm optical path; The fixed-mounted sample arm optical path is fixedly mounted on an adjustment platform of the ophthalmic device, and the handheld sample arm optical path is arranged in a box that can be held by hand.

2. The dual-mode OCTA imaging optical system according to claim 1, characterized in that: The reference arm optical path includes a third collimator, an aperture and a reflector. The first split light beam output from the coupler passes through the third collimator and the aperture in sequence and then reaches the reflector.

3. The dual-mode OCTA imaging optical system according to claim 1, characterized in that: The fixed-mounted sample arm optical path includes a first collimator, a first scanning galvanometer, a first lens, and a second lens. The second split light beam passes through the first collimator and is incident on the first scanning galvanometer. The output light of the first scanning galvanometer passes through the first lens and the second lens in sequence and is incident on the human eye.

4. The dual-mode OCTA imaging optical system according to claim 1, characterized in that: The handheld sample arm optical path includes a second collimator, a second scanning galvanometer, a third lens and a fourth lens. The second split light beam passes through the second collimator and is incident on the second scanning galvanometer. The output light of the second scanning galvanometer passes through the third lens and the fourth lens in sequence and is incident on the human eye.

5. The dual-mode OCTA imaging optical system according to claim 1, characterized in that: The source beam is split into a first sub-beam and a second sub-beam at a ratio of 3:

1.

6. The dual-mode OCTA imaging optical system according to claim 1, characterized in that Also includes: A light source, a coupler and an image acquisition mechanism, wherein the light source and the image acquisition mechanism are respectively connected to the coupler, the coupler is connected to the sample arm optical path and the reference arm optical path, and the image acquisition mechanism is at least used to acquire the light beam reflected by the reference arm optical path.

7. The dual-mode OCTA imaging optical system according to claim 6, characterized in that: The light source includes a low-coherence broadband light source, and the wavelength of the low-coherence broadband light source is 850 nm and the power is 15 mW.

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