Drug mixing device
By designing the pressure difference and baffle structure of the inner reflux cylinder and the outer reflux cylinder in the drug mixing equipment, combined with the stirring effect of the blade mechanism, the problem of insufficient drug mixing under no power device is solved, and efficient drug mixing and Stable operation.
Patent Information
- Application Number
- CN201911051294.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2019-10-31
- Publication Date
- 2024-12-17
- Estimated Expiration
- 2039-10-31
AI Technical Summary
In the prior art, drug mixing equipment without power devices is difficult to ensure the adequacy of drug mixing, resulting in increased operating costs and maintenance costs.
A drug mixing device is designed, including an inner reflux cylinder and an outer reflux cylinder, which guides the circulation of drugs through pressure difference, and uses baffle plates and blade mechanisms to promote mutual collision and fusion of drugs, improves mixing sufficiency, and reduces dependence on the power device.
It realizes the adequacy of drug mixing, saves operating power and maintenance costs, and improves the operating stability of mixing equipment.
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Figure CN112742233B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of drug production, in particular to a drug mixing device. Background Art
[0002] In the process of drug production, it is often necessary to mix solid drugs with liquids, or to mix liquid drugs with liquids. In order to improve the uniformity of drug mixing, a power device is usually added to the mixing equipment in the prior art, and the power device drives the stirring mechanism to stir the drugs. The power device will increase the operating power of the mixing equipment, reduce the stability of operation, and lead to increased operating costs and maintenance costs. However, the mixing equipment without a power device in the prior art is difficult to ensure the adequacy of drug mixing. Summary of the invention
[0003] The purpose of the present invention is to provide a drug mixing device to alleviate the technical problem in the prior art that mixing equipment without a power device is difficult to ensure sufficient drug mixing.
[0004] The above-mentioned purpose of the present invention can be achieved by adopting the following technical solutions:
[0005] The present invention provides a drug mixing device, comprising:
[0006] A mixing cylinder, the lower part of which is provided with a water inlet;
[0007] An inner reflux cylinder is disposed in the mixing cylinder, and the water inlet faces the opening at the lower end of the inner reflux cylinder;
[0008] The outer reflux cylinder surrounds the upper part of the inner reflux cylinder, and the lower part of the inner reflux cylinder is connected to the outer reflux cylinder. The outer reflux cylinder is used to guide the fluid flowing out of the opening at the upper end of the inner reflux cylinder to flow downward.
[0009] In a preferred embodiment, the outer recirculation cylinder is provided with a plurality of first baffles distributed around the axis of the inner recirculation cylinder, each of the first baffles is located between the lower end of the inner recirculation cylinder and the upper end of the inner recirculation cylinder, and one end of the first baffles extends toward the outer recirculation cylinder and the other end extends toward the inner recirculation cylinder; the first baffle is provided with a baffle groove with an opening facing upward, and a first gap is provided between two adjacent first baffles.
[0010] In a preferred embodiment, a plurality of second baffles are provided in the outer recirculation cylinder, and the plurality of second baffles are distributed around the axis of the inner recirculation cylinder, and each of the second baffles is located above the first baffle, and one end of each of the second baffles extends toward the outer recirculation cylinder, and the other end extends toward the inner recirculation cylinder; the second baffle has an upwardly protruding baffle surface, and the baffle surface is used to guide the downwardly flowing fluid to flow into the baffle groove, and a second gap is provided between two adjacent second baffles.
[0011] In a preferred embodiment, the second deflector includes a first flat plate portion and a second flat plate portion, the upper end of the first flat plate portion is connected to the upper end of the second flat plate portion, and the first flat plate portion is inclined from the upper end to the lower end in a direction away from the second flat plate portion, and the second flat plate portion is inclined from the upper end to the lower end in a direction away from the first flat plate portion; the deflection surface is formed on the upper surface of the first flat plate portion and the upper surface of the second flat plate portion.
[0012] In a preferred embodiment, the first deflector includes a third flat plate portion and a fourth flat plate portion, the lower end of the third flat plate portion is connected to the lower end of the fourth flat plate portion, and the third flat plate portion is inclined from the lower end to the upper end in a direction away from the fourth flat plate portion, and the fourth flat plate portion is inclined from the lower end to the upper end in a direction away from the third flat plate portion; the deflection groove is formed on the upper surface of the third flat plate portion and the upper surface of the fourth flat plate portion.
[0013] In a preferred embodiment, a gap channel is provided between the first baffle plate and the second baffle plate, and the gap channel penetrates downwardly through the first baffle plate and the second baffle plate.
[0014] In a preferred embodiment, a spacing is provided between the first baffle and the second baffle in the up-down direction.
[0015] In a preferred embodiment, a blade mechanism is provided at the opening of the upper portion of the inner recirculation cylinder, the blade mechanism is located inside the outer recirculation cylinder, and the rotation axis of the blade mechanism points to the opening at the upper end of the inner recirculation cylinder.
[0016] In a preferred embodiment, the blade mechanism comprises a plurality of axial flow blades.
[0017] In a preferred embodiment, each of the axial flow blades is disposed outside the inner recirculation cylinder, and an outer diameter of the axial flow blade is smaller than an inner diameter of the inner recirculation cylinder.
[0018] In a preferred embodiment, the water inlet is connected to a water inlet pipe, and the water inlet pipe extends into the inner reflux cylinder.
[0019] In a preferred embodiment, the bottom wall of the mixing cylinder has a tapered portion, and the tapered portion is inclined inward from the upper end to the lower end.
[0020] The characteristics and advantages of the present invention are:
[0021] When the drug mixing device is in operation, the drug to be mixed flows into the inner reflux cylinder from the water inlet, flows upward out of the inner reflux cylinder, and enters the chamber between the outer reflux cylinder and the inner reflux cylinder; under the guidance of the outer reflux cylinder, it flows downward and flows into the space between the mixing cylinder body and the outer reflux cylinder, and is discharged through the water outlet arranged on the mixing cylinder body.
[0022] When the medicine to be mixed flows from the water inlet into the inner reflux cylinder, the flow rate is fast, so that the pressure at the bottom of the inner reflux cylinder is relatively low; under the effect of the pressure difference, the medicine to be mixed in the chamber between the outer reflux cylinder and the inner reflux cylinder will enter the inner reflux cylinder again. In this way, the circulation of the medicine to be mixed in the medicine mixing device can be promoted, which is conducive to the collision and fusion of the medicine to be mixed, and improves the adequacy of mixing.
[0023] The drug mixing device can reduce the use of power devices and ensure the adequacy of drug mixing, which is beneficial to saving operating power and maintenance costs and improving operating stability. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0025] Figure 1 A schematic diagram of a drug mixing device provided by the present invention;
[0026] Figure 2 for Figure 1 A schematic structural diagram of a first baffle in a drug mixing device shown;
[0027] Figure 3 for Figure 1 A schematic structural diagram of a second baffle in a drug mixing device shown;
[0028] Figure 4 for Figure 1 AA cross-sectional view;
[0029] Figure 5 for Figure 4 Circumferential development diagram in the B direction;
[0030] Figure 6 for Figure 1A front view of a blade mechanism in the drug mixing device shown;
[0031] Figure 7 for Figure 1 A top view of the blade mechanism in the drug mixing device is shown.
[0032] Description of Figure Numbers:
[0033] 10. mixing cylinder; 101. conical portion; 11. water inlet; 111. water inlet pipe; 112. annular cavity; 12. water outlet;
[0034] 20. Internal reflux cylinder; 21. Reflux port;
[0035] 30. External reflux tube; 31. Diversion outlet
[0036] 40, first baffle; 41, first gap; 42, baffle groove; 431, third flat plate portion; 432, fourth flat plate portion;
[0037] 50, second baffle; 51, second gap; 52, baffle surface; 531, first flat plate portion; 532, second flat plate portion; 54, groove; 55, gap channel; 56, spacing;
[0038] 60. Blade mechanism; 601. Rotating shaft of blade mechanism; 61. Axial flow blade; 62. Gap. DETAILED DESCRIPTION
[0039] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0040] The present invention provides a drug mixing device, such as Figure 1 As shown, the drug mixing device includes: a mixing cylinder 10, an inner reflux cylinder 20 and an outer reflux cylinder 30; a water inlet 11 is provided at the lower portion of the mixing cylinder 10; the inner reflux cylinder 20 is arranged in the mixing cylinder 10, and the water inlet 11 faces the opening at the lower end of the inner reflux cylinder 20; the outer reflux cylinder 30 surrounds the upper portion of the inner reflux cylinder 20, and the lower portion of the inner reflux cylinder 20 is connected to the outer reflux cylinder 30, and the outer reflux cylinder 30 is used to guide the fluid flowing out of the opening at the upper end of the inner reflux cylinder 20 to flow downward.
[0041] When the drug mixing device is in operation, the drug to be mixed flows into the inner reflux cylinder 20 from the water inlet 11, flows upward out of the inner reflux cylinder 20, and enters the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20; under the guidance of the outer reflux cylinder 30, the drug to be mixed flows downward, flows into the space between the mixing cylinder body 10 and the outer reflux cylinder 30, and is discharged through the water outlet 12 arranged on the mixing cylinder body 10.
[0042] When the medicine to be mixed flows from the water inlet 11 into the inner reflux cylinder 20, the flow rate is fast, so that the pressure in the lower area of the inner reflux cylinder 20 is relatively low; under the effect of the pressure difference, the medicine to be mixed in the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20 will enter the inner reflux cylinder 20 again for reflux. In this way, the medicine to be mixed can be promoted to circulate multiple times in the medicine mixing device, which is conducive to the collision and fusion of the medicines to be mixed, and improves the adequacy of mixing.
[0043] The drug mixing device can reduce the use of power devices and ensure the adequacy of drug mixing, which is beneficial to saving operating power and maintenance costs and improving operating stability.
[0044] like Figure 1 As shown, a reflux port 21 is provided between the bottom of the inner reflux cylinder 20 and the bottom wall of the mixing cylinder 10. A diversion outlet 31 is provided between the bottom of the outer reflux cylinder 30 and the bottom wall of the mixing cylinder 10, and the diversion outlet 31 is close to the reflux port 21. The medicine to be mixed in the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20 can flow into the chamber between the mixing cylinder 10 and the outer reflux cylinder 30 through the diversion outlet 31, and can also flow into the inner reflux cylinder 20 through the reflux port 21.
[0045] Furthermore, the water inlet 11 is connected to a water inlet pipe 111, and the water inlet pipe 111 extends into the inner reflux cylinder 20, that is, the inner reflux cylinder 20 surrounds the upper end of the water inlet pipe 111. An annular cavity 112 is formed between the inner reflux cylinder 20 and the water inlet pipe 111, and the water inlet pipe 111 transports the medicine to be mixed to the top of the annular cavity 112, and forms a region with a lower pressure at the upper part of the annular cavity 112, which is conducive to promoting the medicine to be mixed in the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20 to reflux into the inner reflux cylinder 20 through the annular cavity 112. The bottom wall of the mixing cylinder body 10 has a tapered portion 101, and the tapered portion 101 is inclined inward from the upper end to the lower end, and the tapered portion 101 is conducive to guiding the medicine to be mixed flowing out of the outer reflux cylinder 30 to flow toward the center to reflux into the inner reflux cylinder 20.
[0046] In order to make the medicines mixed more fully, the inventors have made further improvements to the medicine mixing device.
[0047] In one embodiment of the present invention, Figure 1 , Figure 2 and Figure 5 As shown, a plurality of first baffles 40 are arranged inside the outer reflux cylinder 30 and distributed around the axis of the inner reflux cylinder 20. Each of the first baffles 40 is located between the lower end of the inner reflux cylinder 20 and the upper end of the inner reflux cylinder 20, and one end of each of the first baffles 40 extends toward the outer reflux cylinder 30 and the other end extends toward the inner reflux cylinder 20. The first baffles 40 are provided with baffle grooves 42 with openings facing upward, and a first gap 41 is provided between two adjacent first baffles 40. When the medicine to be mixed in the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20 flows downward, a part of it continues to flow downward through the first gap 41, and the other part enters the baffle groove 42. The inner wall of the baffle groove 42 guides the medicine to be mixed to flow upward, and the medicine to be mixed flowing upward collides with the medicine flowing downward, so that the medicine is mixed more fully.
[0048] Preferably, the first deflector 40 extends radially along the inner recirculation cylinder 20 , with its inner end connected to the outer wall of the inner recirculation cylinder 20 and its outer end connected to the outer wall of the outer recirculation cylinder 30 .
[0049] Furthermore, if Figure 1-Figure 5 As shown, a plurality of second baffles 50 are arranged in the outer reflux cylinder 30, and the plurality of second baffles 50 are distributed around the axis of the inner reflux cylinder 20, and each second baffle 50 is located above the first baffle 40, and one end of the second baffle 50 extends toward the outer reflux cylinder 30, and the other end extends toward the inner reflux cylinder 20; the second baffle 50 has an upwardly protruding baffle surface 52, and the baffle surface 52 guides the downwardly flowing fluid to flow into the baffle groove 42, and a second gap 51 is arranged between two adjacent second baffles 50. When the medicine to be mixed in the chamber between the outer reflux cylinder 30 and the inner reflux cylinder 20 flows downward, a part of it can flow directly into the baffle groove 42, and another part of it can flow into the baffle groove 42 under the guidance of the baffle surface 52, so as to make the upward reversing flow of the medicine to be mixed more intense, and improve the adequacy of mixing.
[0050] Preferably, the second baffles 50 extend radially along the inner recirculation cylinder 20, with their inner ends connected to the outer wall of the inner recirculation cylinder 20 and their outer ends connected to the outer wall of the outer recirculation cylinder 30. Along the circumference of the inner recirculation cylinder 20, each second baffle 50 is staggered with each first baffle 40.
[0051] The inventor has further optimized the design of the second deflector 50. The second deflector 50 includes a first flat plate portion 531 and a second flat plate portion 532. The upper end of the first flat plate portion 531 is connected to the upper end of the second flat plate portion 532, and the first flat plate portion 531 is inclined from the upper end to the lower end in a direction away from the second flat plate portion 532, and the second flat plate portion 532 is inclined from the upper end to the lower end in a direction away from the first flat plate portion 531; the deflection surface 52 is formed on the upper surface of the first flat plate portion 531 and the upper surface of the second flat plate portion 532, and the deflection surface 52 can more smoothly guide the mixed medicine to flow into the deflection groove 42. Figure 5 As shown, a groove 54 opening downward is formed between the lower surface of the first flat plate portion 531 and the lower surface of the second flat plate portion 532. The medicine to be mixed flowing upward enters the groove 54. The groove 54 will change the flow direction of the medicine to be mixed again, causing it to flow back and forth multiple times, thereby enhancing the intensity of the fusion and collision of the medicine to be mixed and improving the adequacy of the mixing.
[0052] Preferably, the upper end of the first flat plate portion 531 is connected to the upper end of the second flat plate portion 532 to form an upper end profile of the second baffle 50. The extension line of the upper end profile intersects the axis of the inner recirculation cylinder 20, and the upper end profile is perpendicular to the axis of the inner recirculation cylinder 20.
[0053] The inventor has further optimized the design of the first baffle 40. The first baffle 40 includes a third flat plate portion 431 and a fourth flat plate portion 432, the lower end of the third flat plate portion 431 is connected to the lower end of the fourth flat plate portion 432, and the third flat plate portion 431 is inclined from the lower end to the upper end in a direction away from the fourth flat plate portion 432, and the fourth flat plate portion 432 is inclined from the lower end to the upper end in a direction away from the third flat plate portion 431; the baffle groove 42 is formed on the upper surface of the third flat plate portion 431 and the upper surface of the fourth flat plate portion 432, and the width of the baffle groove 42 gradually increases from the lower end to the upper end.
[0054] The upper end of the third flat plate portion 431 is connected to the upper end of the fourth flat plate portion 432 to form the upper end profile of the first baffle 40. The extension line of the upper end profile intersects with the axis of the inner recirculation cylinder 20, and the upper end profile is perpendicular to the axis of the inner recirculation cylinder 20. In the projection on the cross section of the inner recirculation cylinder 20, the central angle between the upper end profiles of two adjacent first baffles 40 is equal to δ, and the central angle between the upper end profiles of two adjacent second baffles 50 is also equal to δ; the central angle between the upper end profile of a first baffle 40 and an adjacent second baffle 50 is equal to θ. Preferably, θ=(1 / 2)δ.
[0055] A gap channel 55 is provided between the first baffle plate 40 and the second baffle plate 50, and the gap channel 55 runs downward through the first baffle plate 40 and the second baffle plate 50, and the gap channel 55 is close to the outer reflux cylinder 30. The medicine to be mixed above the second baffle plate 50 can pass through the first baffle plate 40 and the second baffle plate 50 through the gap channel 55 and flow to the bottom of the first baffle plate 40.
[0056] like Figure 1 As shown, the first baffle 40 and the second baffle 50 are provided with a spacing 56 in the vertical direction. Under the action of the first baffle 40 and the second baffle 50, the medicine to be mixed flows back and forth multiple times in the spacing, so as to promote the full mixing of the medicine to be mixed. Preferably, along the axial direction of the inner reflux cylinder 20, the height of the spacing 56 is equal to 1 to 1.5 times the height of the first baffle 40.
[0057] In one embodiment of the present invention, please refer to Figure 1 , Figure 6 and Figure 7 The upper opening of the inner recirculation cylinder 20 is provided with a blade mechanism 60, the blade mechanism 60 is located in the outer recirculation cylinder 30, and the rotating shaft 601 of the blade mechanism points to the upper opening of the inner recirculation cylinder 20. Figure 1 As described above, the medicine to be mixed in the inner reflux cylinder 20 flows upward, impacts the blade mechanism 60, drives the blade mechanism 60 to rotate, and the blade mechanism 60 causes the flow direction of the medicine to be mixed to change. The rotating blade mechanism 60 stirs the medicine to be mixed, thereby promoting full mixing of the medicine to be mixed.
[0058] Further, the blade mechanism 60 includes a plurality of axial flow blades 61, which are arranged obliquely relative to the rotating shaft 601 of the blade mechanism, so as to facilitate rotation under the impact of the medicine to be mixed. Preferably, the rotating shaft 601 of the blade mechanism is parallel to the axis of the inner reflux cylinder 20. More preferably, the rotating shaft 601 of the blade mechanism coincides with the axis of the inner reflux cylinder 20.
[0059] Furthermore, each axial flow blade 61 is arranged outside the inner reflux cylinder 20, and the outer diameter of the axial flow blade 61 is smaller than the inner diameter of the inner reflux cylinder 20. A gap 62 is formed between the outer contour of the axial flow blade 61 and the inner wall of the inner reflux cylinder 20. The fluid to be mixed in the middle edge part of the inner reflux cylinder 20 can flow upward and outward through the gap 62, and the fluid to be mixed in the central part of the inner reflux cylinder 20 flows through the blade mechanism 60. There is a difference in the flow rates of these two parts of the drugs to be mixed, which facilitates convergence and collision in the chamber between the inner reflux cylinder 20 and the outer reflux cylinder 30, thereby improving the adequacy of mixing.
[0060] In some embodiments, the blade mechanism 60 is provided with a locking mechanism. Depending on the properties of the medicine to be mixed, the blade mechanism can be locked by the locking mechanism to prevent it from rotating.
[0061] The above are only several embodiments of the present invention. Those skilled in the art may make various changes or modifications to the embodiments of the present invention based on the contents disclosed in the application documents without departing from the spirit and scope of the present invention.
Claims
1. A drug mixing device, characterized in that: include: A mixing cylinder, the lower part of which is provided with a water inlet; An inner reflux cylinder is disposed in the mixing cylinder, and the water inlet faces the opening at the lower end of the inner reflux cylinder; An outer reflux cylinder surrounds the upper portion of the inner reflux cylinder, and the lower portion of the inner reflux cylinder is connected to the outer reflux cylinder, and the outer reflux cylinder is used to guide the fluid flowing out of the opening at the upper end of the inner reflux cylinder to flow downward; The outer recirculation cylinder is provided with a plurality of first baffles distributed around the axis of the inner recirculation cylinder, each of the first baffles is located between the lower end of the inner recirculation cylinder and the upper end of the inner recirculation cylinder, and each of the first baffles has one end extending toward the outer recirculation cylinder and the other end extending toward the inner recirculation cylinder; The first baffle plate is provided with a baffle groove with an opening facing upward, and a first gap is provided between two adjacent first baffle plates; A plurality of second baffles are arranged in the outer recirculation cylinder, and the plurality of second baffles are distributed around the axis of the inner recirculation cylinder, and each of the second baffles is located above the first baffle, and one end of each of the second baffles extends toward the outer recirculation cylinder, and the other end extends toward the inner recirculation cylinder; The second baffle plate has a baffle surface protruding upwards, and the baffle surface is used to guide the fluid flowing downward to flow into the baffle groove, and a second gap is provided between two adjacent second baffle plates; The bottom wall of the mixing cylinder has a tapered portion, and the tapered portion is inclined inward from the upper end to the lower end.
2. The drug mixing device according to claim 1, characterized in that: The second deflector includes a first flat plate portion and a second flat plate portion, the upper end of the first flat plate portion is connected to the upper end of the second flat plate portion, and the first flat plate portion is inclined from the upper end to the lower end in a direction away from the second flat plate portion, and the second flat plate portion is inclined from the upper end to the lower end in a direction away from the first flat plate portion; the deflection surface is formed on the upper surface of the first flat plate portion and the upper surface of the second flat plate portion.
3. The drug mixing device according to claim 2, characterized in that: The first deflector includes a third flat plate portion and a fourth flat plate portion, the lower end of the third flat plate portion is connected to the lower end of the fourth flat plate portion, and the third flat plate portion is inclined from the lower end to the upper end in a direction away from the fourth flat plate portion, and the fourth flat plate portion is inclined from the lower end to the upper end in a direction away from the third flat plate portion; the deflection groove is formed on the upper surface of the third flat plate portion and the upper surface of the fourth flat plate portion.
4. The drug mixing device according to claim 1, characterized in that: A gap channel is provided between the first baffle plate and the second baffle plate, and the gap channel penetrates downwardly through the first baffle plate and the second baffle plate.
5. The drug mixing device according to claim 1, characterized in that: The first baffle plate and the second baffle plate are spaced apart in the up-down direction.
6. The drug mixing device according to any one of claims 1 to 5, characterized in that: A blade mechanism is provided at the opening of the upper part of the inner recirculation cylinder. The blade mechanism is located inside the outer recirculation cylinder, and the rotating shaft of the blade mechanism points to the opening of the upper end of the inner recirculation cylinder.
7. The drug mixing device according to claim 6, characterized in that: The blade mechanism includes a plurality of axial flow blades.
8. The drug mixing device according to claim 7, characterized in that: Each of the axial flow blades is arranged outside the inner recirculation cylinder, and the outer diameter of the axial flow blade is smaller than the inner diameter of the inner recirculation cylinder.
9. The drug mixing device according to claim 1, characterized in that: The water inlet is connected to a water inlet pipe, and the water inlet pipe extends into the inner reflux cylinder.
