A flow rate regulating device and invasive blood pressure measuring equipment

Abstract

The present application provides a flow rate regulating device and an invasive blood pressure measuring device using the same, which are used to regulate the flow rate of the liquid flowing through the infusion pipeline of the invasive blood pressure measuring device, and include a first connection part, a flow rate regulating part, and a second connection part, wherein the first connection part, the flow rate regulating part, and the second connection part have a connected liquid circulation pipeline, and the flow rate regulating part includes a cylindrical microporous tube and a flow rate switching tube covering the microporous tube, and the microporous tube is provided with a first micropore and a second micropore, and the liquid flowing through the flow rate regulating part has a first flow rate and a second flow rate, and the second flow rate is greater than the first flow rate. The flow rate regulating device provided in the present application and the invasive blood pressure measuring device using the same can quickly, accurately, conveniently, and reliably regulate the flow rate of the liquid in the invasive blood pressure measuring pipeline and detect the patency of the pipeline.

Description

Technical Field

[0001] The present application relates to the field of invasive blood pressure measurement, and in particular, to a flow rate regulating device and an invasive blood pressure measurement device using the same. Background Art

[0002] Invasive Blood Presure (IBP) measurement is a method of directly measuring blood pressure in blood vessels after puncture and catheterization. It can directly, continuously and dynamically monitor the patient's actual blood pressure. It is widely used in the field of emergency, cardiovascular surgery, intensive care units and surgical anesthesia.

[0003] The principle of invasive blood pressure measurement to obtain blood pressure is: a catheter is inserted through puncture and connected to a perfusion system filled with perfusion fluid (the perfusion fluid is generally normal saline or normal saline with anticoagulants such as heparin) to form a liquid circulation pipeline. Due to the pressure transmission effect of the liquid, the pressure of the perfusion fluid in the pathway is consistent with the pressure in the blood vessels and is transmitted to the probe of the pressure sensor placed in the pathway. The pressure sensor converts the intravascular pressure into an electrical signal and after processing, displays the blood pressure waveform and blood pressure values ​​in a continuous and dynamic manner on a blood pressure display device such as an electrocardiogram monitor screen, including systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure.

[0004] One of the complications of invasive blood pressure measurement is air embolism. If there are bubbles in the liquid circulation pipeline, they may enter the human blood vessels with the backflow of blood and form air embolism. In severe cases, they may enter the cerebral blood vessels and cause cerebral embolism. In addition, the presence of bubbles will also affect the patency of the liquid pipeline and further affect the accuracy of the blood pressure measurement results. Therefore, before puncture, the liquid circulation pipeline needs to be flushed with perfusion fluid to remove all bubbles.

[0005] In the clinical application of invasive blood pressure measurement, it is found that even if the bubbles in the liquid circulation pipeline are completely discharged before puncture, a large number of microbubbles will be generated and attached to the inner wall of the liquid circulation pipeline over time and gradually merge to form larger bubbles. In addition, the blood clots formed at the end of the pipeline in the patient's body may also affect the accuracy of the blood pressure measurement results. Therefore, it is necessary to frequently test the patency of the liquid pipeline in clinical practice to ensure the accuracy and safety of the blood pressure measurement results.

[0006] Existing invasive blood pressure measurement equipment usually uses a slender columnar lifting portion provided on the flow rate regulating device to perform the above-mentioned detection. Specifically, by pulling up and then releasing the lifting portion, the flow rate of the perfusion fluid flowing through the flow rate regulating device and the pressure sensor pipeline is changed, and the liquid pressure detected by the pressure sensor is changed. Further, by judging the change amplitude and change speed of the liquid pressure displayed on the blood pressure display device, it is detected whether there are bubbles, blood clots and other factors that affect the patency of the pipeline in the invasive blood pressure measurement pipeline.

[0007] In actual use, there are the following problems: the slender columnar lifting part is easily broken, making it impossible to detect the patency of the pipeline; the different pulling amplitudes each time lead to different changes in the flow rate, which in turn causes different changes in the liquid pressure waveform and affects its interpretation; in addition, there are certain inconveniences in pulling up the slender lifting part. Therefore, it is necessary to provide a convenient, reliable, and highly consistent flow rate regulating device and an invasive blood pressure measurement device using the same, so as to meet the needs of quickly, accurately, conveniently, and reliably detecting the patency of the invasive blood pressure measurement pipeline when performing invasive blood pressure measurement on patients. Summary of the invention

[0008] To solve the above problems, the present application provides a flow rate regulating device and an invasive blood pressure measurement device including the flow rate regulating device, which is used to quickly, accurately, conveniently and reliably detect the patency of the invasive blood pressure measurement pipeline when performing invasive blood pressure measurement on a patient.

[0009] One aspect of the present application provides a flow rate regulating device, comprising a first connecting part, a flow rate regulating part, and a second connecting part, wherein the first connecting part, the flow rate regulating part, and the second connecting part have a connected liquid circulation pipeline; the flow rate regulating part comprises a cylindrical microporous tube and a flow rate switching tube covering the microporous tube, and the microporous tube is provided with a first micropore and a second micropore; the liquid flowing through the flow rate regulating part has a first flow rate for invasive blood pressure measurement and a second flow rate for detecting the patency of the invasive blood pressure measurement pipeline, and the second flow rate is greater than the first flow rate.

[0010] Preferably, the first flow rate is 2 to 4 ml / hour, and the second flow rate is 10 to 60 ml / minute.

[0011] Furthermore, the microporous tube is made of a hard material, and the flow rate switching tube is made of an elastic soft material.

[0012] Furthermore, the first micropore is located at the radial center of the microporous tube and penetrates the microporous tube axially; the second micropore has a first opening located on the upper side of the outer wall of the microporous tube and a second opening located on the upper part of the cross section of the microporous tube toward one end of the second connecting portion.

[0013] Furthermore, the flow rate switching tube includes a hollow elastic circular tube, annular sealing parts located at both ends of the hollow elastic circular tube, and an axial push-pull part located at the upper part of the outer wall of the hollow elastic circular tube; the hollow elastic circular tube covers the microporous tube by interference fit, and the inner wall of the hollow elastic circular tube covers the first opening toward the outer edge of one end of the first connecting part; the annular sealing part is formed by axially extending from both ends of the hollow elastic circular tube, and the inner wall diameter of the annular sealing part is larger than the outer wall diameter of the microporous tube.

[0014] Further, the first connecting portion includes a first liquid pipeline, a first truncated cone-shaped protrusion extending axially from one end of the first liquid pipeline toward the flow rate regulating portion, a first sealing groove located outside the first truncated cone-shaped protrusion, a first guide groove located at the upper part of the end of the first liquid pipeline toward the flow rate regulating portion and the upper part of the first truncated cone-shaped protrusion, a first limiting portion located at the lower part of the first liquid pipeline, and a pipeline joint located at the end of the first liquid pipeline away from the flow rate regulating portion; the second connecting portion includes a second liquid pipeline, a first sealing groove located at the axial end of the second liquid pipeline toward the flow rate regulating portion A second truncated cone-shaped protrusion extending toward the microporous tube, a second sealing groove located outside the second truncated cone-shaped protrusion, a second guide groove located at the upper part of the second liquid pipeline facing the end of the flow rate regulating part and the upper part of the second truncated cone-shaped protrusion, and a second limiting part located at the lower part of the second liquid pipeline; the inner wall diameter of the first liquid pipeline is smaller than the outer wall diameter of the microporous tube and the inner wall diameter of the first truncated cone-shaped protrusion is larger than the outer wall diameter of the microporous tube; the inner wall diameter of the second liquid pipeline is smaller than the outer wall diameter of the microporous tube and the inner wall diameter of the second truncated cone-shaped protrusion is larger than the outer wall diameter of the microporous tube.

[0015] Furthermore, the first sealing groove and the second sealing groove are sealed and connected to the annular sealing portion by interference fit, and the bottom surfaces of the first sealing groove and the second sealing groove are in non-fixed contact with the end surface of the annular sealing portion; the first limiting portion and the second limiting portion are detachably fixedly connected; the end surface of the first liquid pipeline facing one end of the flow rate regulating portion and the end surface of the second liquid pipeline facing one end of the flow rate regulating portion are in non-fixed contact with the end surfaces at both ends of the microporous tube.

[0016] Furthermore, the first connecting part is connected to the infusion pipeline of the blood pressure measuring device through a pipeline joint; the second connecting part is fixedly connected to the pressure sensor of the blood pressure measuring device, and the second liquid pipeline is connected to the liquid pipeline of the pressure sensor.

[0017] Preferably, the liquid flowing through the flow rate regulating portion also has a third flow rate, and the third flow rate is greater than the second flow rate; the flow rate switching tube also includes extrusion sheets located on both sides of the upper outer wall of the hollow elastic circular tube.

[0018] Beneficial effects of this application

[0019] The flow rate regulating device and invasive blood pressure measurement equipment of the embodiment of the present application set the micropores of the microporous tube to two, and the microporous tube is axially limited by the first liquid pipeline and the second liquid pipeline. By pulling and loosening the axial limiting part, the second micropore is switched between the liquid flow state and the closed state, and the liquid flowing through the flow rate regulating device is further switched between the second flow rate and the first flow rate, thereby causing the conversion of the liquid pressure waveform obtained by the pressure sensor. The flow rate regulating device of the embodiment of the present application can maintain the stability of the second flow rate, solving the problem of inconsistent liquid pressure waveform caused by the unstable state when the lifting part of the existing flow rate regulating device is lifted; the embodiment of the present application also solves the problem that the lifting part is easily broken, resulting in the inability to perform invasive blood pressure measurement pipeline patency detection; at the same time, the pulling of the axial push-pull part of the embodiment of the present application is simpler and faster than the operation of pulling up the lifting part in the existing method, which helps to more conveniently perform invasive blood pressure measurement pipeline patency detection.

[0020] Another aspect of the present application also provides an invasive blood pressure measurement device, which can detect the patency of the invasive blood pressure measurement pipeline when performing invasive blood pressure measurement on a patient, including an infusion pipeline, a pressurizable infusion bag, a syringe, a pressure sensor, a blood pressure display device, a zeroing three-way valve, a three-way valve, a puncture device and an intravascular catheter; and also includes the flow rate regulating device. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the assembly of the existing flow rate regulating part;

[0022] Figure 2 This is a system framework diagram of an invasive blood pressure measurement device according to an embodiment of the present application;

[0023] Figure 3 for Figure 2 A partial enlarged view of the circled part;

[0024] Figure 4 A three-dimensional view of a microporous tube cut along the BB direction according to an embodiment of the present application;

[0025] FIG5( a) is a perspective view of a flow rate switching tube according to an embodiment of the present application;

[0026] FIG5( b ) is a three-dimensional view of the assembly of the flow rate switching tube and the microporous tube cut along the BB direction according to an embodiment of the present application;

[0027] Figure 6 It is a partial enlarged view of the circled part in Figure 5(b);

[0028] Figure 7 A three-dimensional diagram of a first connecting portion of an embodiment of the present application;

[0029] Figure 8 A three-dimensional view of a first connecting portion BB of an embodiment of the present application cut in half;

[0030] Fig. 9 A three-dimensional diagram of a second connecting portion of an embodiment of the present application;

[0031] Fig.10 A half-cut perspective view of the second connecting portion BB of the embodiment of the present application;

[0032] Fig.11 It is an assembly explosion diagram of the flow rate regulating device of an embodiment of the present application;

[0033] FIG12( a ) is a plan view of the flow rate regulating device according to an embodiment of the present application cut along the BB axis in an invasive blood pressure measurement state;

[0034] FIG12( b ) is a partial enlarged view of the circled portion of FIG12( a );

[0035] FIG. 13( a ) is a plan view cut along the BB direction of the flow rate regulating device according to an embodiment of the present application, when the axial push-pull portion is moved to detect the patency of an invasive blood pressure measurement pipeline;

[0036] FIG13( b ) is a partial enlarged view of the circled portion of FIG13( a );

[0037] Fig.14 A flow chart of performing patency detection of an invasive blood pressure measurement line for an invasive blood pressure measurement device according to an embodiment of the present application;

[0038] FIG. 15( a ) is a schematic diagram of a conversion state of a liquid pressure waveform when the invasive blood pressure measurement pipeline is unobstructed according to an embodiment of the present application;

[0039] FIG15( b ) is a schematic diagram of the conversion state of the pressure waveform when there are bubbles, blood clots, and other factors that affect the patency of the invasive blood pressure measurement pipeline in an embodiment of the present application.

[0040] Numbers in the figure

[0041] 1 flow rate regulating device, 11 first connecting part, 111 first liquid pipeline, 112 first truncated cone protrusion, 113 first sealing groove, 114 first flow guide groove, 115 first limit part, 116 pipeline joint, 12 flow rate regulating part, 121 microporous tube, 1211 first micropore, 1212 second micropore, 1213 first opening, 1214 second opening, 122 flow rate switching tube, 1221 hollow elastic round tube, 1222 annular sealing part, 1223 axial push-pull part, 1224 extrusion sheet, 13 second connecting part, 131 second liquid pipeline, 132 second truncated cone protrusion, 133 second sealing groove, 134 second guide groove, 135 second limiting part, 2 pressure sensor, 21 wire, 3 blood pressure display device, 4 infusion pipeline, 5 perfusion device, 6 pressurized infusion bag, 7 roller regulator, 8 zero calibration three-way valve, 9 three-way valve, 10 puncture connector, 101 intravascular catheter. DETAILED DESCRIPTION

[0042] The present application is further described below based on preferred implementation modes and in conjunction with the accompanying drawings. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0043] In addition, various components on the drawings are enlarged (thickened) or reduced (thinned) for ease of understanding, but this practice is not intended to limit the scope of protection of the present application.

[0044] Words importing the singular also include the plural and vice versa.

[0045] In the description of the embodiments of the present application, it should be noted that if the terms "upper", "lower", "inner", "outer", etc. indicate an orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly placed when the embodiments of the present application are used, it is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In addition, in the description of the present application, in order to distinguish different units, the words first, second, etc. are used in this specification, but these are not limited by the order of manufacture, nor can they be understood as indicating or implying relative importance, and their names may be different in the detailed description of the application and the claims.

[0046] The vocabulary in this specification is used to illustrate the embodiments of the present application, but is not intended to limit the present application. It should also be noted that, unless otherwise clearly specified and limited, the terms "disposed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, a direct connection, an indirect connection through an intermediate medium, or a connection between the two components. For those skilled in the art, the specific meanings of the above terms in this application can be specifically understood.

[0047] Before describing the embodiments of the present application, we first introduce the flow rate regulating unit of the existing blood pressure measuring device. Figure 1 The figure is a schematic diagram of the assembly of the flow rate regulating part of the existing blood pressure measuring device. Figure 1 As shown, the flow rate regulating portion of the existing blood pressure measuring device includes a cylindrical microporous tube made of a hard material and a flow rate switching tube made of a soft elastic material covering the microporous tube (for clear explanation, the flow rate switching tube in the figure is cut along the AA direction), the flow rate switching tube covers the microporous tube through an interference fit and is sealed and connected to the connecting parts at both ends respectively. In the invasive blood pressure measurement state, the perfusion liquid in the invasive blood pressure measurement pipeline can only flow through the micropores located at the radial center of the microporous tube. When it is necessary to detect the patency of the invasive blood pressure measurement pipeline, the pulling portion located on the upper part of the flow rate switching tube is pulled upward. Due to the elasticity of the flow rate switching tube, a liquid passage is formed between the flow rate switching tube and the microporous tube, so that the perfusion liquid in the invasive blood pressure measurement pipeline can flow through the micropores of the microporous tube and the liquid passage between the flow rate switching tube and the microporous tube at the same time. By adjusting the flow rate of the perfusion fluid flowing through the above-mentioned flow rate regulating part, the liquid pressure detected by the pressure sensor can be changed. Further, by judging the change amplitude and change speed of the liquid pressure displayed on the blood pressure display device, it is possible to detect whether there are bubbles, thrombi and other factors that affect the patency of the pipeline in the invasive blood pressure measurement pipeline.

[0048] In actual use, the following problems exist when using the above-mentioned existing flow rate regulating part and its connecting parts to perform invasive blood pressure measurement pipeline patency detection: (1) The slender columnar pulling part is easily broken, making it impossible to perform pipeline patency detection; (2) The different pulling amplitudes each time cause different flow rate changes, which in turn causes different changes in the liquid pressure waveform and affects its interpretation; (3) In addition, pulling up the slender pulling part also causes certain inconveniences.

[0049] Therefore, it is necessary to provide a convenient, reliable and consistent flow rate regulating device and an invasive blood pressure measurement device using the same, so as to meet the needs of quickly, accurately, conveniently and reliably detecting the patency of the invasive blood pressure measurement pipeline when performing invasive blood pressure measurement on patients.

[0050] One aspect of an embodiment of the present application provides a flow rate regulating device for regulating the flow rate of a liquid flowing through an infusion line of an invasive blood pressure measurement device. Figure 2 The system structure diagram of the invasive blood pressure measurement device including the flow rate regulating device 1 of the embodiment of the present application is shown. Figure 3 for Figure 1 A partial enlarged view of the circled part, such as Figure 2 , Figure 3 As shown, the flow rate regulating device 1 comprises a first connecting portion 11, a flow rate regulating portion 12 and a second connecting portion 13, and the first connecting portion 11, the flow rate regulating portion 12 and the second connecting portion 13 have a communicating liquid circulation pipeline;

[0051] The liquid flowing through the flow rate regulating portion 12 has a first flow rate for invasive blood pressure measurement and a second flow rate for detecting the patency of the invasive blood pressure measurement pipeline, and the first flow rate is greater than the second flow rate.

[0052] In the embodiments of the present application, the pressure sensor 2, the wire 21, the blood pressure display device 3, the infusion line 4, the syringe 5, the pressurized infusion bag 6, the roller regulator 7, the zeroing three-way valve 8, the three-way valve 9, the puncture connector 10 and the intravascular catheter 101 of the invasive blood pressure measurement equipment are all standard components or common components known to those skilled in the art, and their structures and principles are known to those skilled in the art.

[0053] Preferably, the first flow rate is 2 to 4 ml / hour, and the second flow rate is 10 to 60 ml / minute.

[0054] Furthermore, the flow rate regulating portion 12 includes a cylindrical microporous tube 121 and a flow rate switching tube 122 covering the microporous tube 121; the microporous tube 121 is made of a hard material, and the flow rate switching tube 122 is made of an elastic soft material.

[0055] In some specific implementations of the embodiments of the present application, the microporous tube 121 can be made of hard materials such as medical glass, medical metal, medical plastic, etc., and the flow rate switching tube 122 can be made of elastic soft polymer materials such as medical silicone.

[0056] The following combination Figures 4 to 6 The structure and assembly method of the microporous tube 121 and the flow rate switching tube 122 are described in detail.

[0057] Furthermore, if Figure 4As shown, the microporous tube 121 is provided with a first micropore 1211 and a second micropore 1212, the first micropore 1211 is located at the radial center of the microporous tube 121 and penetrates the microporous tube 121 axially; the second micropore 1212 has a first opening 1213 located on the upper side of the outer wall of the microporous tube 121 and a second opening 1214 located on the upper part of the cross section of the microporous tube 121 at one end toward the second connecting portion 13.

[0058] Furthermore, as shown in Figures 5(a) and 5(b), the flow rate switching tube 122 includes a hollow elastic circular tube 1221, annular sealing portions 1222 located at both ends of the hollow elastic circular tube 1221, and an axial push-pull portion 1223 located at the upper portion of the outer wall of the hollow elastic circular tube 1221; the hollow elastic circular tube 1221 covers the microporous tube 121 by interference fit; the inner wall of the hollow elastic circular tube 1221 covers the first opening 1213 toward the outer edge of one end of the first connecting portion 11; the annular sealing portion 1222 is formed by axial extension from both ends of the hollow elastic circular tube 1221, and the inner wall diameter of the annular sealing portion 1222 is larger than the outer wall diameter of the microporous tube 121.

[0059] Specifically, in the specific implementation of this embodiment, the hollow elastic tube 1221 and the annular sealing portions 1222 located at both ends of the hollow elastic tube 1221, and the axial push-pull portion 1223 located at the upper portion of the outer wall of the hollow elastic tube 1221 can be integrally formed by molding or the like, and the inner wall diameter of the hollow elastic tube 1221 is slightly smaller than the outer wall diameter of the microporous tube 121, so that the hollow elastic tube 1221 covers the microporous tube 121 by interference fit, such as Figure 6 As shown, the outer edge of the hollow elastic circular tube 1221 toward one end of the first connecting part covers the first opening 1213, and the inner wall diameter of the annular sealing part 1222 is larger than the outer wall diameter of the microporous tube 121, so that in the assembled state, the liquid between the inner wall of the annular sealing part 1222 and the outer wall of the microporous tube 121 can only flow through the first micropore 1211.

[0060] The following combination Figures 7 to 10 The specific structures of the first connecting portion 11 and the second connecting portion 13 of the embodiment of the present application are described in detail.

[0061] In the embodiment of the present application, the first connecting portion 11 includes a first liquid pipeline 111, a first truncated cone-shaped protrusion 112 extending axially from one end of the first liquid pipeline 111 toward the flow rate regulating portion 12, a first sealing groove 113 located outside the first truncated cone-shaped protrusion 112, a first guide groove 114 located at the upper part of the end of the first liquid pipeline 111 toward the flow rate regulating portion 12 and the upper part of the first truncated cone-shaped protrusion 112, a first limiting portion 115 located at the lower part of the first liquid pipeline 111, and a pipeline joint 116 located at the end of the first liquid pipeline 111 away from the flow rate regulating portion 12; the second connecting portion 13 includes a second liquid pipeline 131, a first sealing groove 113 located outside the first truncated cone-shaped protrusion 112, and a first sealing groove 114 located at the upper part of the end of the first liquid pipeline 111 toward the flow rate regulating portion 12 and the upper part of the first truncated cone-shaped protrusion 112. 12, a second truncated cone-shaped protrusion 132 axially extending from one end of the microporous tube 12, a second sealing groove 133 located outside the second truncated cone-shaped protrusion 132, a second guide groove 134 located at the upper part of the second liquid pipeline 131 facing the flow rate regulating part 12 and the upper part of the second truncated cone-shaped protrusion 132, and a second limiting portion 135 located at the lower part of the second liquid pipeline 131; the inner wall diameter of the first liquid pipeline 111 is smaller than the outer wall diameter of the microporous tube 121 and the inner wall diameter of the first truncated cone-shaped protrusion 112 is larger than the outer wall diameter of the microporous tube 121; the inner wall diameter of the second liquid pipeline 131 is smaller than the outer wall diameter of the microporous tube 121 and the inner wall diameter of the second truncated cone-shaped protrusion 132 is larger than the outer wall diameter of the microporous tube 121.

[0062] Specifically, in the specific implementation of the embodiment of the present application, Figure 7 , Figure 8 As shown, the first liquid pipeline 111 extends axially toward one end of the flow rate regulating part 12 and the inner wall diameter increases to form a first truncated cone-shaped protrusion 112. The outer wall of the first truncated cone-shaped protrusion 112 can be designed as a gradually closing cone. The first sealing groove 113 is an annular groove surrounding the outer side of the first truncated cone-shaped protrusion 112, which is formed by the tube wall of the first liquid pipeline 111 being thickened radially and then extending axially in the form of an annular groove; a through first guide groove 114 is provided at the upper part of the end of the first liquid pipeline 111 toward the flow rate regulating part 12 and the upper part of the first truncated cone-shaped protrusion 112, which is used to form a connected liquid passage between the first liquid pipeline 111 and the flow rate regulating part 12; the first limit portion 115 is located at the lower part of the first liquid pipeline 111; the pipeline connector 116 can be a standard Rolle connector, which is located at the end of the first liquid pipeline 111 away from the flow rate regulating part 12 and is used to connect the infusion pipeline.

[0063] Specifically, in the specific implementation of the embodiment of the present application, Fig. 9 , Fig.10As shown, the second liquid pipeline 131 extends axially toward one end of the flow rate regulating portion 12 and the inner wall diameter increases to form a second truncated cone-shaped protrusion 132. The outer wall of the second truncated cone-shaped protrusion 132 can be designed to be a gradually closing cone. The second sealing groove 133 is an annular groove surrounding the outer side of the second truncated cone-shaped protrusion 132. It is formed by the tube wall of the second liquid pipeline 131 being radially thickened and then extending axially in the form of an annular groove; a second through-flow guide groove 134 is provided at the upper part of the second liquid pipeline 131 at one end of the flow rate regulating portion 12 and the upper part of the second truncated cone-shaped protrusion 132, which is used to form a connected liquid passage between the second liquid pipeline 131 and the flow rate regulating portion 12; the second limiting portion 135 is located at the lower part of the second liquid pipeline 131.

[0064] In the specific implementation method of the embodiment of the present application, the first connecting part 11 can be made in one piece by injection molding or the like; the second connecting part can be made in one piece with the outer shell of the pressure sensor 2 by injection molding or the like, and the second liquid pipeline 131 forms a connected liquid circulation pipeline with the liquid pipeline of the pressure sensor 2.

[0065] The following, combined Figure 2 , Figure 11 to Figure 13(b) The assembly method of the flow rate regulating device 1 and the internal liquid flow conditions in the invasive blood pressure measurement state and the state of detecting the patency of the invasive blood pressure measurement pipeline are described in detail.

[0066] In an embodiment of the present application, the first sealing groove 113 and the second sealing groove 133 are sealed and connected to the annular sealing portion 1222 by interference fit, and the bottom surfaces of the first sealing groove 113 and the second sealing groove 133 are in non-fixed contact with the end surface of the annular sealing portion 1222; the first limiting portion 115 and the second limiting portion 135 are detachably fixedly connected; the end surface of the first liquid pipeline 111 toward one end of the flow rate regulating portion 12 and the end surface of the second liquid pipeline 131 toward one end of the flow rate regulating portion 12 are in non-fixed contact with the end surfaces at both ends of the microporous tube 121.

[0067] Specifically, in the specific implementation of the embodiment of the present application, Figure 11 to Figure 13(b) As shown, the annular sealing parts 1222 at both ends of the hollow elastic circular tube 1221 enter the first sealing groove 113 and the second sealing groove 133 respectively, and their end faces are non-fixedly contacted with the bottom surfaces of the first sealing groove 113 and the second sealing groove 133 respectively, and the elasticity of the annular sealing part 1222 is utilized to achieve a sealed connection through interference fit.

[0068] Specifically, in the specific implementation of the embodiment of the present application, Figure 11 to Figure 13(b)As shown, the end faces of both ends of the microporous tube 121 are in non-fixed contact with the end face of the first liquid pipeline 111 facing the flow rate regulating portion 12 and the end face of the second liquid pipeline 131 facing the flow rate regulating portion 12, respectively. Since the outer wall diameter of the microporous tube 121 is larger than the inner wall diameter of the first liquid pipeline 111 and the second liquid pipeline 131, the microporous tube 121 is axially limited by the first liquid pipeline 111 and the second liquid pipeline 131; the liquid fills the space between the microporous tube 121 and the annular sealing portion 1222 through the first guide groove 114 and the second guide groove 134.

[0069] like Figure 2 As shown, the flow rate regulating device 1 of the embodiment of the present application is placed in an invasive blood pressure measuring device, one end of which is connected to a pressurized infusion bag 6 and a syringe 5, and the other end is connected to a pressure sensor 2, a zero calibration three-way valve 8, a three-way valve 9, and a puncture connector 10. The puncture connector 10 is connected to an intravascular catheter 101, so that the invasive blood pressure measuring device forms a connected liquid flow path from the pressurized infusion bag 6 to the tip of the intravascular catheter 101. At this time, the blood pressure at the tip of the intravascular catheter 101 is the blood pressure to be measured, and the pressure sensor 2 displays the measured blood pressure data and waveform on the blood pressure display device 3 through the wire 21.

[0070] When the invasive blood pressure measurement device is in the invasive blood pressure measurement state, as shown in FIG. 12( a ) and the partially enlarged view of FIG. 12( b ), the outer edge of the hollow elastic tube 1221 toward one end of the first connecting portion 11 covers the first opening 1213 , so that the second micropore 1212 is closed. At this time, the perfusion liquid in the invasive blood pressure measurement pipeline can only flow through the flow rate regulating portion 12 through the first micropore 1211 and enter the liquid pipeline of the pressure sensor 2. The perfusion liquid passing through the first micropore 1211 has a first flow rate. Preferably, the first flow rate is 2 to 4 ml / hour. At this flow rate, the liquid pressure in the liquid pipeline inside the pressure sensor 2 is consistent with the blood pressure at the tip of the intravascular catheter 101. At this time, the data measured by the pressure sensor 2 and displayed on the blood pressure display device 3 is the blood pressure to be measured;

[0071] When it is necessary to test the patency of the invasive blood pressure measurement pipeline, the axial push-pull portion 1223 is pulled toward the second connection portion 13 and held for a period of time before being released. As shown in FIG. 13(a) and the partially enlarged view of FIG. 13(b), due to the elasticity of the flow rate switching tube 122, the movement of the axial push-pull portion 1223 toward the second connection portion 13 drives the hollow elastic circular tube 1221 to move slightly toward the second connection portion 13, and the microporous tube 121 is axially limited by the second liquid pipeline 131, so that the outer edge of the hollow elastic circular tube 1221 toward one end of the first connection portion 11 no longer covers the first opening 1213. At this time, the perfusion liquid passes through the first micropore 1211 and the second micropore 1211 at the same time. The micropore 1212 flows through the flow rate regulating part 12 at a second flow rate and enters the liquid pipeline of the pressure sensor 2. Preferably, the second flow rate is 10 to 60 ml / min. At this flow rate, the perfusion liquid pressure in the liquid pipeline inside the sensor is consistent with the liquid pressure in the infusion pipeline 4 at one end of the syringe 5. At this time, the data measured by the pressure sensor 2 and displayed on the blood pressure display device 3 is the liquid pressure in the infusion pipeline 4 at one end of the syringe 5, which is greater than the blood pressure at the tip of the intravascular catheter 101.

[0072] After loosening the axial push-pull portion 1223, the axial push-pull portion 1223 drives the hollow elastic circular tube 1221 to reset toward the second connecting portion 13. At this time, since the microporous tube 121 is axially limited by the first connecting portion 11, the outer edge of the hollow elastic circular tube 1221 toward one end of the first connecting portion 11 re-covers the first opening 1213, thereby re-closing the second micropore 1212. The liquid flow rate flowing through the flow rate regulating portion 12 and entering the liquid pipeline of the pressure sensor 2 is returned to the first flow rate, so that the perfusion fluid in the liquid pipeline of the pressure sensor 2 re-establishes pressure transmission with the blood at the tip of the intravascular catheter 101, and the data measured by the pressure sensor 2 and displayed on the blood pressure display device 3 is returned to the blood pressure at the tip of the intravascular catheter 101.

[0073] When there are factors such as bubbles and blood clots that affect the patency of the invasive blood pressure measurement pipeline, the time it takes for the perfusion fluid in the liquid pipeline of the pressure sensor 2 to re-establish pressure transmission with the blood at the tip of the intravascular catheter 101 is longer than when the pipeline is unobstructed. This is reflected on the blood pressure display device 3, that is, there are differences in the time it takes for the pressure waveform to recover from high pressure to periodic blood pressure and the waveform change. By interpreting the above differences, the patency of the invasive blood pressure measurement pipeline can be quickly and accurately detected.

[0074] Preferably, the liquid flowing through the flow rate regulating portion 12 also has a third flow rate, which is greater than the second flow rate; the flow rate switching tube 122 also includes extrusion sheets 1224 located on both sides of the upper outer wall of the hollow elastic circular tube 1221.

[0075] Specifically, in the embodiment of the present application, as shown in FIG. 5( a ), the flow rate switching tube 122 further includes extrusion sheets 1224 symmetrically arranged on both sides of the upper outer wall of the hollow elastic circular tube 1221. By pinching the extrusion sheets 1224 and squeezing toward the middle of the flow rate switching tube 122, the hollow elastic circular tube 1221 will be extruded and deformed, thereby forming a liquid flow channel between the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121. At this time, the perfusion liquid simultaneously passes through the first micropore 1211, the second micropore 1212, and the liquid flow channel between the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121, and passes through the flow rate regulating part 12 at a third flow rate. The third flow rate is much greater than the second flow rate, and can be used to flush the infusion line 4 before invasive blood pressure measurement to remove bubbles in the infusion line 4.

[0076] The flow rate regulating device 1 and the invasive blood pressure measuring device of the embodiment of the present application set the micropores of the microporous tube 121 to two, and the microporous tube 121 is axially limited by the first liquid pipeline 111 and the second liquid pipeline 131. By pulling and loosening the axial push-pull portion 1223, the second micropore 1212 is switched between the liquid flow state and the closed state, and the liquid flowing through the flow rate regulating device 1 is further switched between the second flow rate and the first flow rate, thereby causing the conversion of the liquid pressure waveform obtained by the pressure sensor 2. The flow rate regulating device 1 of the embodiment of the present application can maintain the stability of the second flow rate, and solves the problem of inconsistent liquid pressure waveform caused by the unstable state when the lifting portion of the existing flow rate regulating device is lifted; the embodiment of the present application also solves the problem that the lifting portion is easily broken, resulting in the inability to perform invasive blood pressure measurement pipeline patency detection; at the same time, the pulling of the axial push-pull portion 1223 of the embodiment of the present application is simpler and faster than the operation of pulling up the lifting portion in the existing embodiment, which helps to more conveniently perform invasive blood pressure measurement pipeline patency detection.

[0077] On the other hand, this embodiment also provides an invasive blood pressure measurement device, which can detect the patency of the invasive blood pressure measurement pipeline when the patient's blood pressure is being invasively measured, including an infusion pipeline 4, a pressurizable infusion bag 6, a syringe 5, a pressure sensor 2, a blood pressure display device 3, a zeroing three-way valve 8, a three-way valve 9, a puncture connector 10 and an intravascular catheter 101, and also includes a flow rate regulating device 1.

[0078] Specifically, the invasive blood pressure measurement device provided in this embodiment is as follows: Figure 2 As shown, it includes an infusion line 4, a pressurized infusion bag 6, a perfusion device 5, a pressure sensor 2, a blood pressure display device 3, a zero calibration three-way valve 8, a three-way valve 9 and a puncture connector 10, and also includes a flow rate regulating device 1, through which Fig.14 The process shown is to check the patency of the invasive blood pressure measurement line:

[0079] S1: Pull the axial push-pull portion toward the second connection portion and keep it for a period of time;

[0080] S2: reading the pressure waveform at the second flow rate measured by the pressure sensor from the blood pressure display device;

[0081] S3: loosening the axial push-pull portion;

[0082] S4: reading the pressure waveform at the first flow rate measured by the pressure sensor from the blood pressure display device;

[0083] S5: judging the patency of the pipeline of the invasive blood pressure measurement device according to the state of conversion from the liquid pressure waveform at the second flow rate to the liquid pressure waveform at the first flow rate.

[0084] Specifically, the assembly method of the flow rate regulating device 1 in the invasive blood pressure measurement state and the invasive blood pressure measurement pipeline patency detection state, the internal liquid flow condition and the liquid pressure condition measured by the pressure sensor of the present embodiment have been described in detail above and will not be repeated here.

[0085] Figure 15(a) shows the waveform conversion diagram of the liquid pressure when the invasive blood pressure measurement pipeline of this embodiment maintains good patency, and Figure 15(b) shows the waveform conversion diagram of the liquid pressure when the invasive blood pressure measurement pipeline of this embodiment has bubbles, blood clots and other factors that affect the patency of the pipeline.

[0086] When the measuring pipeline maintains good patency, when executing the above steps S1 to S4, the liquid pressure in the liquid pipeline of the pressure sensor 2 quickly changes from being consistent with the liquid pressure in the infusion pipeline 4 at one end of the infusion device 5 to being consistent with the blood pressure at the tip of the intravascular catheter 101. Correspondingly, the waveform displayed on the blood pressure display device 3 presents a steep falling edge, and then restores the periodically changing blood pressure waveform; when there are bubbles or thrombi in the measuring pipeline, it will affect the patency of the measuring pipeline, prolonging the pressure transmission time. Correspondingly, the time for the liquid pressure in the liquid pipeline of the pressure sensor 2 to return to being consistent with the blood pressure at the tip of the intravascular catheter 101 becomes longer, and the waveform displayed on the blood pressure display device 3 presents a slow falling edge, and then restores the periodically changing blood pressure waveform. By analyzing the conversion state of the liquid pressure waveform at the second flow rate to the liquid pressure waveform at the first flow rate, the patency of the invasive blood pressure measurement pipeline can be determined.

[0087] The above is a detailed introduction to the specific implementation methods of the present application. For those skilled in the art, several improvements and modifications may be made to the present application without departing from the principles of the present application. These improvements and modifications also fall within the scope of protection of the claims of the present application.

Claims

1. A flow rate regulating device for regulating the flow rate of a liquid flowing through an infusion pipeline of an invasive blood pressure measurement device, comprising a first connecting portion, a flow rate regulating portion, and a second connecting portion, wherein the first connecting portion, the flow rate regulating portion, and the second connecting portion have a connected liquid circulation pipeline, characterized in that: The flow rate regulating part comprises a cylindrical microporous tube and a flow rate switching tube covering the microporous tube, wherein the microporous tube is provided with a first micropore and a second micropore; The liquid flowing through the flow rate regulating part has a first flow rate for invasive blood pressure measurement and a second flow rate for detecting the patency of the invasive blood pressure measurement pipeline, and the second flow rate is greater than the first flow rate; The first micropore is located at the radial center of the microporous tube and penetrates the microporous tube in the axial direction; The second micropore has a first opening located on the upper side of the outer wall of the microporous tube and a second opening located on the upper part of the cross section of the microporous tube toward one end of the second connecting portion; The flow rate switching tube comprises a hollow elastic circular tube, annular sealing parts located at both ends of the hollow elastic circular tube, and an axial push-pull part located at the upper part of the outer wall of the hollow elastic circular tube; The hollow elastic tube covers the microporous tube by interference fit, and the inner wall of the hollow elastic tube covers the first opening toward the outer edge of one end of the first connecting portion; The annular sealing portion is formed by extending the two ends of the hollow elastic circular tube in the axial direction, and the inner wall diameter of the annular sealing portion is larger than the outer wall diameter of the microporous tube; The first connecting portion is connected to the infusion pipeline of the blood pressure measuring device through a pipeline joint; The second connecting portion is fixedly connected to the pressure sensor of the blood pressure measuring device, and the second liquid pipeline is in communication with the liquid pipeline of the pressure sensor; The liquid flowing through the flow rate regulating portion also has a third flow rate, and the third flow rate is greater than the second flow rate; The flow rate switching tube also includes extrusion sheets located on both sides of the upper portion of the outer wall of the hollow elastic circular tube; The first connecting portion includes a first liquid pipeline and a first truncated cone-shaped protrusion located at one end of the first liquid pipeline and extending axially toward the flow rate regulating portion. The outer wall of the first truncated cone-shaped protrusion is designed to be a gradually closing cone.

2. A flow rate regulating device as claimed in claim 1, characterized in that: The first flow rate is 2 to 4 ml / hour, and the second flow rate is 10 to 60 ml / minute.

3. A flow rate regulating device as claimed in claim 2, characterized in that: The microporous tube is made of a hard material, and the flow rate switching tube is made of an elastic soft material.

4. A flow rate regulating device as claimed in claim 1, characterized in that: The first connecting portion further includes a first sealing groove located outside the first truncated cone-shaped protrusion, a first guide groove located at an upper portion of an end of the first liquid pipeline facing the flow rate regulating portion and an upper portion of the first truncated cone-shaped protrusion, a first limit portion located at a lower portion of the first liquid pipeline, and a pipeline joint located at an end of the first liquid pipeline away from the flow rate regulating portion; The second connecting portion includes a second liquid pipeline, a second truncated cone-shaped protrusion extending axially from one end of the second liquid pipeline toward the flow rate regulating portion, a second sealing groove located outside the second truncated cone-shaped protrusion, a second guide groove located at the upper part of the end of the second liquid pipeline toward the flow rate regulating portion and the upper part of the second truncated cone-shaped protrusion, and a second limiting portion located at the lower part of the second liquid pipeline; The inner wall diameter of the first liquid pipeline is smaller than the outer wall diameter of the microporous tube, and the inner wall diameter of the first truncated cone-shaped protrusion is larger than the outer wall diameter of the microporous tube; The inner wall diameter of the second liquid pipeline is smaller than the outer wall diameter of the microporous tube, and the inner wall diameter of the second truncated cone-shaped protrusion is larger than the outer wall diameter of the microporous tube.

5. A flow rate regulating device as claimed in claim 4, characterized in that: The first sealing groove and the second sealing groove are sealed and connected to the annular sealing portion by interference fit, and the bottom surfaces of the first sealing groove and the second sealing groove are in non-fixed contact with the end surface of the annular sealing portion; The first limiting portion and the second limiting portion are detachably fixedly connected; The end surface of the first liquid pipeline facing one end of the flow rate regulating part and the end surface of the second liquid pipeline facing one end of the flow rate regulating part are in non-fixed contact with the end surfaces at both ends of the microporous tube.

6. An invasive blood pressure measurement device capable of detecting the patency of an invasive blood pressure measurement line while performing invasive blood pressure measurement on a patient, comprising an infusion line, a pressurizable infusion bag, a syringe, a pressure sensor, a blood pressure display device, a zeroing three-way valve, a three-way valve, a puncture connector and an intravascular catheter, characterized in that: It also includes a flow rate regulating device as described in any one of claims 1 to 5.

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