A cell analysis system

Abstract

The application discloses a cell analysis system with normal reading mode and priority reading mode, which comprises: a smear preparation device configured to prepare a smear containing a sample; a conventional transmission device configured to sequentially transmit the smear to a cell morphology analysis device along a first path; a priority transmission device configured to transmit the smear to the cell morphology analysis device along a second path different from the first path; and the cell morphology analysis device configured to image and analyze cells in the smear; in the normal reading mode, the control device causes the cell morphology analysis device to image and analyze the smear transmitted by the conventional transmission device; in the priority reading mode, the control device causes the cell morphology analysis device to image and analyze the smear transmitted by the priority transmission device in priority to at least one smear on the conventional transmission device.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of cell analysis, in particular to a cell analysis system. BACKGROUND

[0002] The film reading machine, also known as a cell morphology analyzer, is an instrument used to analyze cells on smears of peripheral blood, pathogens, bone marrow, body fluids, etc. The core module is a microscopic camera system (hereinafter also referred to as an imaging device), which captures cells on a sample smear into a color image and distinguishes the types of cells through intelligent recognition algorithms. Before reading the film, a microscope slide with a sample coating needs to be prepared. The instrument for preparing the slide (hereinafter also referred to as the test smear) is usually a slide staining machine (hereinafter also referred to as a smear preparation device).

[0003] The slide staining machine is used online with the film reading machine to realize sample collection, smear preparation, smear staining, and smear detection (also known as film reading). When working online, the slides are queued in a first-in, first-out strategy for slide pushing and film reading. During film reading, a single slide is generally transferred from the slide staining machine to the film reading machine one by one, or multiple slides are placed in a fixed container (such as a slide basket or a slide box) as a group and transferred to the film reading machine or a film reading module for film reading.

[0004] In actual sample pushing, staining, and reading tests, in special cases, some samples need to be prepared immediately for film reading in the film reading machine, while waiting for the previous smears. However, the current cell analysis system cannot achieve the above purpose.

[0005] Therefore, it is necessary to improve the current cell analysis system to solve the problems in the prior art. SUMMARY

[0006] A series of simplified concepts are introduced in the summary section, which will be further described in detail in the specific embodiments section. The summary section of the present application does not mean to attempt to limit the key features and necessary technical features of the claimed technical solution, nor to determine the protection scope of the claimed technical solution.

[0007] In order to overcome the existing problems, the present application provides a cell analysis system, which has a normal film reading mode and a queue-jumping film reading mode, and comprises a smear preparation device, a conventional transmission device, a priority transmission device, a cell morphology analysis device, and a control device.

[0008] The smear preparation device is configured to prepare test smears containing samples.

[0009] The conventional transmission device is configured to sequentially transmit the test smears to the cell morphology analysis device along a first path.

[0010] The priority transmission device is configured to transmit the to-be-tested smear to the cell morphology analysis device along a second path different from the first path.

[0011] The cell morphology analysis device is configured to perform image shooting and analysis on the cells in the to-be-tested smear.

[0012] In the normal reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the to-be-tested smear transmitted by the regular transmission device; and in the queue-reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the to-be-tested smear transmitted by the priority transmission device, which is prior to at least one to-be-tested smear on the regular transmission device.

[0013] Optionally, the control device is configured to, in the normal reading mode, control the cell morphology analysis device to receive the to-be-tested smear transmitted by the regular transmission device to perform image shooting and analysis on the to-be-tested smear; and in the queue-reading mode, control the cell morphology analysis device to receive the to-be-tested smear transmitted by the priority transmission device to cause the to-be-tested smear transmitted by the priority transmission device to be prior to image shooting and analysis on at least one to-be-tested smear on the regular transmission device.

[0014] Optionally, the control device is arranged in the cell morphology analysis device.

[0015] Optionally, the control device is configured to, in the normal reading mode, control the smear preparation device to output the to-be-tested smear to the regular transmission device, and in the queue-reading mode, control the smear preparation device to output the to-be-tested smear to the priority transmission device.

[0016] Optionally, the control device is arranged in the smear preparation device.

[0017] Optionally, the control device is configured to schedule the to-be-tested smears of the regular transmission device and the priority transmission device, in the normal reading mode, control the regular transmission device to transmit the to-be-tested smear to the cell morphology analysis device, and in the queue-reading mode, control the priority transmission device to transmit the to-be-tested smear to the cell morphology analysis device.

[0018] Optionally, in the queue-reading mode, the to-be-tested smear in the priority transmission device is prior to all the to-be-tested smears on the priority transmission device to enter the cell morphology analysis device for image shooting and analysis.

[0019] Optionally, the priority transmission device comprises a priority transmission channel configured to transmit the test smear to the cell morphology analysis device along a second path different from the first path.

[0020] Optionally, two ends of the priority transmission channel are connected to the outlet of the smear preparation device and the viewing inlet of the cell morphology analysis device, respectively.

[0021] Optionally, the priority transmission channel is partially arranged in the smear preparation device, or partially arranged in the cell morphology analysis device, or independently arranged outside the smear preparation device and the cell morphology analysis device.

[0022] Optionally, the test smear transmitted by the priority transmission device is a single smear or a plurality of smears placed in a smear container.

[0023] Optionally, the routine transmission device comprises a routine transmission channel configured to sequentially transmit the test smears to the cell morphology analysis device along the first path, and the routine transmission channel is partially arranged in the smear preparation device, or partially arranged in the cell morphology analysis device, or independently arranged outside the smear preparation device and the cell morphology analysis device.

[0024] Optionally, the priority transmission device comprises a priority transmission channel, and the outlet of the priority transmission channel and the outlet of the routine transmission channel are both in communication with the viewing inlet of the cell morphology analysis device.

[0025] The inlet of the priority transmission channel and the inlet of the routine transmission channel are in communication, and / or the inlets of the priority transmission channel and the routine transmission channel are both directly in communication with the outlet of the smear preparation device.

[0026] Optionally, the priority transmission channel and the routine transmission channel are arranged side by side and are both connected to the same sample feeding channel, and the sample feeding channel is connected to the viewing inlet of the cell morphology analysis device.

[0027] Optionally, in the priority viewing mode, the smear preparation device is configured to preferentially prepare the test smear transmitted by the priority transmission device.

[0028] Optionally, the priority transmission device comprises a mechanical hand configured to transmit the test smear to the cell morphology analysis device along a second path different from the first path.

[0029] Optionally, the priority transmission device comprises a single-sample feeding device arranged in the cell morphology analysis device to receive a manually placed test smear.

[0030] Optionally, the single-sample loading device is automatically ejected from the cell analysis device, or

[0031] The single-sample loading device is manually pulled out of the cell analysis device to receive the test smear.

[0032] The single-sample loading device is fixedly arranged in the cell analysis device to receive the test smear manually placed therein.

[0033] Optionally, the single-sample loading device comprises a buffer mechanism arranged in the cell analysis system, the buffer mechanism having a first buffer accommodating portion configured to buffer the test smear and a second buffer accommodating portion configured to receive the test smear manually placed therein.

[0034] Optionally, the cell analysis system starts the priority reading mode when the test smear is placed in the single-sample loading device.

[0035] Optionally, the control device is configured to prompt the test smear to be placed in the priority transmission device when the priority reading mode instruction is received.

[0036] Optionally, the priority reading mode instruction is triggered by a user or automatically triggered when the detection result of the blood analyzer is abnormal.

[0037] Optionally, the control device is further configured to set the shooting mode of the test smear in the priority reading mode.

[0038] Optionally, the control device is configured to use the autonomously set shooting mode, select a default mode, or select the shooting mode according to the information of the sample.

[0039] Optionally, the cell morphology analysis device is provided with a control panel configured to select the normal reading mode and the priority reading mode through the control panel.

[0040] The cell analysis system of the present application is provided with a priority transmission device in addition to a conventional transmission device, and has a normal reading mode and a priority reading mode; in the normal reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the test smear transmitted by the conventional transmission device; in the priority reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the test smear transmitted by the priority transmission device, which has priority over at least one test smear on the conventional transmission device. Through the improvement, the test smear that needs to be immediately placed in the cell morphology analysis device after smear preparation can be preferentially subjected to image shooting and analysis, without queuing, thereby improving the detection efficiency of emergency samples. Attached Figure Description

[0041] The following drawings, which are incorporated herein by reference as part of this invention, are provided for understanding the invention. The drawings illustrate embodiments of the invention and their descriptions, serving to explain the principles of the invention.

[0042] In the attached image:

[0043] Figure 1 This is a schematic diagram of the structure of the cell analysis system according to one embodiment of the present invention;

[0044] Figure 2 This is a schematic diagram of the smear preparation device in the cell analysis system according to one embodiment of the present invention;

[0045] Figure 3 This is a schematic diagram of the structure of the cell morphology analysis device in the cell analysis system according to an embodiment of the present invention;

[0046] Figure 4 This is a structural block diagram of the cell morphology analysis device in the cell analysis system according to an embodiment of the present invention;

[0047] Figures 5A-5G This is a simplified schematic diagram illustrating the configuration of the conventional transmission device and the priority transmission device of the cell analysis system described in one embodiment of the present invention. Detailed Implementation

[0048] To make the objectives, technical solutions, and advantages of this application more apparent, exemplary embodiments according to this application will be described in detail below with reference to the accompanying drawings. Obviously, the described embodiments are merely some embodiments of this application, and not all embodiments of this application. It should be understood that this application is not limited to the exemplary embodiments described herein. Based on the embodiments of this application described herein, all other embodiments obtained by those skilled in the art without inventive effort should fall within the protection scope of this application.

[0049] The following description provides numerous specific details to offer a more thorough understanding of this application. However, it will be apparent to those skilled in the art that this application can be practiced without one or more of these details. In other instances, certain technical features well-known in the art have not been described to avoid confusion with this application.

[0050] It should be understood that this application can be implemented in various forms and should not be construed as being limited to the embodiments set forth herein. Rather, providing these embodiments will make the disclosure thorough and complete, and will fully convey the scope of this application to those skilled in the art.

[0051] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and / or "comprising", when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and / or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items. The use of the terms first, second, third, etc. is only to distinguish one from another, and does not limit one or more embodiments to a certain order or sequence.

[0052] For a thorough understanding of the application, detailed descriptions will be made in the following description and specific embodiments will be presented to illustrate the technical solutions of the application. The preferred embodiments of the application are described in detail as follows, however, the application can have other embodiments in addition to these detailed descriptions.

[0053] For better understanding of the arrangement of the conventional transmission device and the priority transmission device described in the application, the following first describes the arrangement of the conventional transmission device Figure 1 The overall structure of the cell analysis system is described and explained, and it should be noted that, Figure 1 The cell analysis system described in the above is only exemplary and is not limited to the structures and implementations listed. As Figure 1 As shown in the figure, the cell analysis system 100 at least includes a smear preparation device 120, a cell morphology analysis device 130 and a control device 140.

[0054] Optionally, the cell analysis system 100 can further include a blood analyzer 110 for performing routine blood tests on the smear to be tested, for example, when the blood analyzer 110 detects a sample with abnormal results, the cell morphology analysis device 130 can be used for further analysis of the morphology of the cells, and it should be noted that the blood analyzer 110 is not necessary for the cell analysis system 100 of the application.

[0055] The smear preparation device 120 is used to prepare the smear to be tested, the cell morphology analysis device 130 is used to take images and analyze the cells in the smear, and the control device 140 is used to control at least one of the blood analyzer 110, the smear preparation device 120 and the cell morphology analysis device 130.

[0056] In the embodiments of the application, the control device 140 can be arranged in the cell analysis system 100, as Figure 1The control device 140 is communicatively connected to the blood analyzer 110, the smear preparation device 120 and the cell morphology analysis device 130. In other embodiments, the control device 140 can also be provided in the blood analyzer 110, or in the smear preparation device 120, or in the cell morphology analysis device 130, for controlling one or more of the blood analyzer 110, the smear preparation device 120 and the cell morphology analysis device 130.

[0057] The cell analysis system 100 further comprises a first conveying track 150 for conveying the test tube rack 10 loaded with the test sample-containing test tubes 11 from the blood analyzer 110 to the smear preparation device 120, and a second conveying track 160 for conveying the slide basket 20 loaded with the prepared smears 21 from the smear preparation device 120 to the cell morphology analysis device 130.

[0058] The cell analysis system 100 further comprises feeding mechanisms 170 and 180 provided in the blood analyzer 110 and the smear preparation device 120 respectively, each of the feeding mechanisms 170 and 180 comprising a loading buffer area 171 and 181, a feeding detection area 172 and 182, and an unloading buffer area 173 and 183.

[0059] When the test sample in the test tube rack 10 needs to be conveyed to the blood analyzer 110 for detection, the test tube rack 10 is first conveyed from the first conveying track 150 to the loading buffer area 171, then from the loading buffer area 171 to the feeding detection area 172 for detection by the blood analyzer 110, after the detection is completed, the test tube rack 10 is unloaded from the feeding detection area 172 to the unloading buffer area 173, and finally the test tube rack 10 is conveyed from the unloading buffer area 173 to the first conveying track 150.

[0060] Similarly, when the test sample in the test tube rack 10 needs to be subjected to microscopic examination, the test tube rack 10 needs to be conveyed to the smear preparation device 120 for smear preparation. The test tube rack 10 is first conveyed from the first conveying track 150 to the loading buffer area 181, then from the loading buffer area 181 to the feeding detection area 182 for smear preparation by the smear preparation device 120, after the smear preparation is completed, the test tube rack 10 is unloaded from the feeding detection area 182 to the unloading buffer area 183, and finally the test tube rack 10 is conveyed from the unloading buffer area 183 to the first conveying track 150. The prepared smears are stored in the slide basket 20 by the smear preparation device 120, and the slide basket 20 containing the test smears is conveyed to the cell morphology analysis device 130 by the second conveying track 160, and the cell morphology analysis device 130 takes images of the cells in the test sample on the test smears and performs analysis.

[0061] The cell analysis system 100 further comprises a display device (not shown) for displaying the sample detection result, which can be arranged on the blood analyzer 110, the smear preparation device 120, the cell morphology analysis device 130 or the control device 140, or arranged separately.

[0062] The smear preparation device 120 in the present application can be used for smear preparation of blood, body fluid and other samples. As shown in Figure 2 and Figure 3 The smear preparation device comprises a sampling mechanism 121 for extracting the sample, a slide loading mechanism 122 for moving the slide to the working line, a sample loading mechanism 123 for loading the sample to the slide, a slide pushing mechanism 124 for smearing the sample on the slide, a drying mechanism (not shown in the figure) for drying the blood film on the slide, and a staining mechanism 125 for staining the slide. The sample loading mechanism 123 further comprises a mechanical clamp 1231.

[0063] When the sampling mechanism 121 extracts the sample, the sample is first mixed, and then the sample is sucked by the sampling device (such as a sampling needle) in the sampling mechanism 121. According to different sample containers, the sample can be sucked by puncture (the sample container has a cover, and the sampling device penetrates the cover of the sample container), or the sample can be sucked directly from the open part (the sample container is open, and the sampling device directly sucks the sample from the open part). If necessary, blood sample information detection can be performed to obtain information and compare information. In some embodiments, the micro-sample loading mechanism 126 can move the test tube directly put by the operator to the direction of the sampling device, or the sampling device can move to the direction of the test tube directly put by the operator. In other implementations, the micro-sample loading mechanism 126 can also move the test tube directly to the direction of the sample loading mechanism 123, or the sample loading mechanism 123 can move to the direction of the test tube directly put by the operator, and the sample loading is performed after the blood sample is sucked directly by the sample loading mechanism 123 (such as a blood dropper). Since the blood does not need to be extracted by the sampling mechanism 121, the demand for blood sample can be reduced, thereby realizing micro-sample and priority sample loading. After the sampling is completed, the blood is prepared to be dropped on the slide by the sample loading mechanism 123.

[0064] Correspondingly, the slide loading mechanism 122 extracts the slide and loads the slide to the corresponding position to facilitate the blood dropping operation. In some embodiments, after the slide extraction operation is completed, the slide left-right detection and slide cleaning operations can also be performed, and then the slide is loaded. The loaded slide can print relevant information, and the slide front-back detection operation can also be performed.

[0065] The blood drop needle of the sample adding mechanism 123 drops the sample onto the slide and then performs a slide pushing operation. The blood on the slide is pushed into a blood film shape by the slide pushing mechanism 124. Generally, after the slide pushing operation is completed, the blood film on the slide can be dried to stabilize the shape. In some embodiments, the slide can be flipped before the blood film is dried to meet the corresponding requirements. In some embodiments, the dried blood smear can also be subjected to a drying detection to determine the drying effect of the blood film. In some embodiments, the dried blood smear can also be subjected to a blood film unfolding detection to determine whether the blood film is unfolded and whether the unfolded state meets the requirements. After the slide pushing is completed, the slide (blood smear) can be stained (which can be achieved by the staining mechanism 125) or directly output (for example, placed into the slide basket 20 for output)

[0066] In embodiments of the present application, as shown in Figure 4 The cell morphology analysis device 130 at least includes an imaging device 131, a slide moving device 132, and an image analysis device 133. The imaging device 131 includes a camera 1312 and a lens group 1311 and is used to take pictures of cells in the sample smeared on the slide. The slide moving device 132 is used to move the slide relative to the imaging device 131 so that the imaging device 131 takes cell images of specific areas of the slide. The image analysis device 133 is used to analyze the cell images of the slide.

[0067] As shown in Figure 4 The lens group 1311 can include a first objective lens, a second objective lens, and an eyepiece. The first objective lens can be, for example, a 10x objective lens, and the second objective lens can be, for example, a 100x objective lens. The lens group 1311 can also include a third objective lens, which can be, for example, a 40x objective lens. The lens group 1311 can also include an eyepiece.

[0068] The cell morphology analysis device 130 further includes an identification device 134, a slide clamping device 135, and a slide recycling device 136. The identification device 134 is used to identify the identity information of the slide. The slide clamping device 135 is used to clamp the slide from the identification device 134 to the slide moving device 132 for detection. The slide recycling device 136 is used to place the detected slide.

[0069] The cell morphology analysis device 130 further includes a slide basket loading device 137 for loading a slide basket containing slides to be detected. The slide clamping device 135 is also used to clamp the slides to be detected in the slide basket loaded on the slide basket loading device 137 to the identification device 134 for identity information identification. The slide basket loading device 137 is connected with the first transmission track 160 so that the slide prepared by the slide preparation device 120 can be transported to the cell morphology analysis device 130.

[0070] It should be noted that the cell analysis system 100 in the above examples is only used to illustrate the basic structure and working principle of the cell analysis system 100, and the structure of the cell analysis system 100 is not limited thereto.

[0071] In addition to the above-mentioned structure, the cell analysis system 100 in the embodiment of the present application further comprises a conventional transmission device, a priority transmission device and a control device, and the cell analysis system 100 has a normal reading mode and a priority reading mode; in different reading modes, the priority order of the test smears subjected to microscopic examination is different. In the normal reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the test smears transmitted by the conventional transmission device; in the priority reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the test smears transmitted by the priority transmission device, which has priority over at least one test smear on the conventional transmission device. The conventional transmission device, the priority transmission device and the control device, and the two reading modes will be described in detail below.

[0072] In the present application, the control device is used to control the transmission path of the test smears, and when the priority reading mode is triggered, the control device controls the cell morphology analysis device to perform image shooting and analysis on the test smears transmitted by the priority transmission device, which has priority over at least one test smear on the conventional transmission device.

[0073] The control device can be set in the following three ways:

[0074] First, the control device is arranged in the cell analysis system 100, which is used to realize the control of each device, functional device and module in the cell analysis system 100, and realize the control and scheduling of the whole cell analysis system 100.

[0075] The control device can be the control device 140 in the cell analysis system 100, or a separately arranged control device.

[0076] When the control device is arranged in the cell analysis system 100, the control device can control the conventional transmission device and the priority transmission device at the same time to schedule the test smears of the conventional transmission device and the priority transmission device; in the normal reading mode, the control device controls the conventional transmission device to transmit test smears to the cell morphology analysis device, and in the priority reading mode, the control device controls the priority transmission device to transmit test smears to the cell morphology analysis device.

[0077] Secondly, the control device controls the detection order of the smears by controlling the smear preparation device 120 to output the smears in a certain order.

[0078] For example, in the normal reading mode, the control device controls the smear preparation device to output the smears to the normal transmission device for image shooting and analysis; in the queue-reading mode, the control device controls the smear preparation device to output the smears to the priority transmission device, so that the smears output to the priority transmission device are given priority to be shot and analyzed over the smears on the normal transmission device.

[0079] In the above control modes, the control device can be arranged in the smear preparation device 120, but is not limited to this example.

[0080] Thirdly, the control device controls the detection order of the smears by controlling the smear preparation device to output the smears in a certain order. For example, in the normal reading mode, the control device controls the smear preparation device to output the smears to the normal transmission device; in the queue-reading mode, the control device controls the smear preparation device to output the smears to the priority transmission device, and when a smear is input to the priority transmission device, the priority reading mode is started.

[0081] In the above control modes, the control device can be arranged in the smear preparation device 120, but is not limited to this example. In addition, when the control device is arranged in the smear preparation device 120, the control device can also control the detection order of the smears by controlling the smear preparation device to prepare the smears in a certain order.

[0082] For example, in the normal reading mode, the control device controls the smear preparation device to prepare the smears for normal shooting and analysis and output to the normal transmission device; in the queue-reading mode, the control device controls the smear preparation device to preferentially prepare the queue smears and output to the priority transmission device.

[0083] It should be noted that no matter where the control device is arranged in the smear analysis system 100, the smear preparation device can be controlled to preferentially prepare the queue smears and output to the priority transmission device.

[0084] The conventional transmission device can transmit the smear prepared by the smear preparation device to the cell morphology analysis device for shooting and analysis. In addition, the conventional transmission device can also serve as a queuing buffer. For example, the smear prepared by the smear preparation device 120 can be queued on the conventional transmission device for transmission to the cell morphology analysis device.

[0085] The conventional transmission device has a first path through which the smear prepared by the smear preparation device is sequentially transmitted to the cell morphology analysis device.

[0086] The conventional transmission device can be configured in various ways. For example, the conventional transmission device can be configured as a transmission channel through which the smear is transmitted to the cell morphology analysis device. Alternatively, the conventional transmission device can be configured as a loading device through which the smear is clamped into the cell morphology analysis device.

[0087] For example, in an embodiment of the present application, the conventional transmission device includes a conventional transmission channel that sequentially transmits the smear to the cell morphology analysis device along a first path.

[0088] The conventional transmission channel can be a second transmission track 160 or a track similar to the second transmission track 160. The first path can be the transmission path of the second transmission track 160. It should be noted that the conventional transmission device can also be configured in other structures that can achieve the above functions, which are not listed here.

[0089] The two ends of the conventional transmission device are respectively connected to the cell morphology analysis device 130 and the smear preparation device 120.

[0090] The following will be described in detail with reference to the accompanying drawings. Figures 5A-5G The conventional transmission channel 220 will be described in detail. In an embodiment of the present application, as shown in Figure 5A 、 5B , 5C and 5F, one end (the inlet) of the conventional transmission channel 220 is connected to the outlet of the smear preparation device 120 to receive the smear prepared by the smear preparation device 120, and the other end (the outlet) of the conventional transmission channel 220 is connected to the inlet of the cell morphology analysis device 130 to transmit the smear into the cell morphology analysis device 130.

[0091] Optionally, the cell analysis system 100 can further include an intermediate connecting piece 230, as shown in Figure 5DAs shown, the two ends of the intermediate connector 230 are respectively connected to the cell morphology analysis device 130 and the smear preparation device 120. The inlet of the conventional transmission channel 220 can be connected to the intermediate connector 230, or the outlet of the conventional transmission channel 220 can be connected to the intermediate connector 230, or both the inlet and outlet of the conventional transmission channel 220 can be connected to the intermediate connector 230. With this configuration, the smear to be tested prepared by the smear preparation device 120 can be transferred to the conventional transmission channel 220 through the intermediate connector 230, and the smear to be tested in the conventional transmission channel 220 can also be transferred to the cell morphology analysis device 130 through the intermediate connector 230.

[0092] The connection position between the conventional transmission channel 220 and the intermediate connector 230 can be set according to actual needs. In one embodiment of the present invention, the entrance of the conventional transmission channel 220 can be connected to any position on the transmission path of the intermediate connector 230, such as a position near the entrance of the intermediate connector 230, without limitation.

[0093] In another embodiment of the present invention, the outlet of the conventional transmission channel 220 may be connected to any position of the transmission path of the intermediate connector 230, for example, near the outlet of the intermediate connector 230, without limitation.

[0094] The intermediate connector 230 is used to receive the smear to be tested or a slide basket for holding the smear. Both ends of the intermediate connector can be connected to the smear preparation device and the cell morphology analysis device.

[0095] The intermediate connector 230 may be a storage compartment or a glass slide basket for placing containers, or it may be a transmission path that is different from that of a conventional transmission device, etc., without further limitation.

[0096] The location of the conventional transmission channel 220 can be selected according to actual needs, and the conventional transmission channel 220 can be partially disposed within the smear preparation device, such as... Figure 5A , 5B As shown in Figure 5E; or partially disposed within the cell morphology analysis device, such as... Figure 5C , 5D and Figure 5G ; or it can be independently located outside of the smear preparation device and the cell morphology analysis device, such as Figure 5F .

[0097] The setting mode of the priority transmission device will be described in detail below. In the present application, the priority transmission device can include a priority transmission channel, a robot, a single chip sample feeding device, etc., as long as it can give priority to the sample to be tested for image shooting and analysis over at least one sample to be tested on the regular transmission device in the sample review mode.

[0098] The present application will be described in detail below with reference to the accompanying drawings. Figures 5A-5G The setting mode of the priority transmission channel will be described. The priority transmission channel 210 has a second path different from the first path. In the sample review mode, the sample to be tested is transmitted to the cell morphology analysis device through the second path to avoid the first path, so that the sample in the sample review mode can be detected preferentially without queuing in the regular transmission channel. In the present application, the sample in the sample review mode can be transmitted preferentially to the cell morphology analysis device by setting the sample review mode and the priority transmission device, so that the problem of queuing and waiting for a long time can be avoided.

[0099] The two ends of the priority transmission channel 210 are connected to the outlet of the smear preparation device and the sample review inlet of the cell morphology analysis device, respectively.

[0100] In an embodiment of the present application, as shown in Figures 5A-5G , the inlet of the priority transmission channel 210 is in communication with the outlet of the smear preparation device 120 to receive the sample to be tested prepared by the smear preparation device 120, and the outlet of the priority transmission channel 210 is in communication with the inlet of the cell morphology analysis device 130 to transmit the sample to be tested into the cell morphology analysis device 130.

[0101] Optionally, the cell analysis system 100 can further include an intermediate connecting piece 230. The priority transmission channel 210 can be arranged on the intermediate connecting piece 230, or the intermediate connecting piece 230 and the priority transmission channel 210 are entirely overlapped, i.e., the intermediate connecting piece constitutes the priority transmission channel 210 as a whole, as shown in Figure 5G , in which case the intermediate connecting piece 230 and the priority transmission channel 210 are the same structure.

[0102] The setting position of the priority transmission channel 210 can be selected according to actual needs. The priority transmission channel 210 can be partially arranged in the smear preparation device, as shown in Figure 5A , 5B , 5D, 5E and 5F; or partially arranged in the cell morphology analysis device, as shown in Figure 5A , 5B , 5C, 5D, 5E, and Figure 5GOr independently arranged outside the smear preparation device and the cell morphology analysis device.

[0103] In the present application, the normal transmission device and the priority transmission device can be independent devices without association with each other, and each device operates independently. For example, when the normal transmission device is a conventional transmission channel and the priority transmission device is a mechanical hand and a single chip sampling device, the normal transmission device and the priority transmission device do not overlap or cross each other in arrangement. When the normal transmission device is a conventional transmission channel and the priority transmission device is a priority transmission channel, the conventional transmission channel and the priority transmission channel can be arranged independently without mutual interference, or can be connected to each other, or even share part of the transmission path.

[0104] The positional relationship between the conventional transmission channel and the priority transmission channel will be described in detail below.

[0105] In an embodiment of the present application, the inlet and outlet of the conventional transmission channel and the priority transmission channel are arranged separately.

[0106] In another embodiment of the present application, as shown in FIG. 2, the conventional transmission channel 220 and the priority transmission channel 210 are connected to each other. Through the arrangement, the smear to be tested in the priority transmission channel 210 can be transmitted to the cell morphology analysis device 130, and the smear to be tested in the conventional transmission channel 220 can be first transmitted to the priority transmission channel 210, and then transmitted to the cell morphology analysis device 130 for shooting and analysis through the priority transmission channel 210, as shown in FIG. 3, especially the smear to be tested in the conventional transmission channel 220 close to the priority transmission channel 210. Figures 5A-5G Figure 5B

[0107] In the example of the present application, the priority transmission channel 210 and the conventional transmission channel 220 can be connected to each other at the inlet, or at the outlet, or at any position on the priority transmission channel 210 or the conventional transmission channel 220, so that the smears to be tested in the priority transmission channel 210 and the conventional transmission channel 220 can be transmitted to each other.

[0108] In the example of the present application, the priority transmission channel 210 and the conventional transmission channel 220 can be connected to each other at the inlet, or at the outlet, or at any position on the priority transmission channel 210 or the conventional transmission channel 220, so that the smears to be tested in the priority transmission channel 210 and the conventional transmission channel 220 can be transmitted to each other.

[0109] ​​Optionally, the priority transmission channel 210 and the normal transmission channel 220 can be provided with separate outlets, or can share one outlet, and the test slides are transmitted into the cell morphology analysis device 130 through different channels according to the urgency or priority of the smear.

[0110] In an example, as shown in Figure 5A and 5B the outlet of the priority transmission channel 210 and the outlet of the normal transmission channel 220 are both communicated with the reading inlet of the cell morphology analysis device; the inlet of the priority transmission channel 210 is communicated with the inlet of the normal transmission channel 220;

[0111] or as shown in Figure 5D the inlet of the priority transmission channel and the inlet of the normal transmission channel are both directly communicated with the outlet of the smear preparation device.

[0112] or, as shown in Figure 5F the priority transmission channel and the normal transmission channel are arranged side by side and are both connected to the same sample inlet channel, which is connected to the reading inlet of the cell morphology analysis device.

[0113] The priority transmission channel 210 can be arranged at any position, which is not limited to the above examples, and can be selected according to actual needs. The above examples are only illustrative.

[0114] The test slides in the priority transmission channel and / or the normal transmission channel can be single slides or multiple slides placed in a slide container, such as a group of test slides placed in a slide basket, which is not limited herein.

[0115] In the embodiment of the present application, when the priority transmission device is a mechanical hand, the test slides are transmitted by the mechanical hand into the cell morphology analysis device through a second path different from the first path for shooting and analysis.

[0116] The priority transmission device can also be a mechanical clamp with the same function as the mechanical hand, as long as it can place the test slides on a detection platform, which can be a microscopic camera detection platform, which is not listed here.

[0117] In the embodiment of the present application, the priority transmission device can also be a single-slide sample inlet device. In the priority reading mode, the test slides are preferentially transmitted into the cell morphology analysis device through the single-slide sample inlet device for image shooting and analysis.

[0118] Optionally, the single slide loading device can accept a test slide manually put into the single slide loading device, and in the slide insertion mode, the test slide in the single slide loading device has priority over at least one test slide on the regular conveying device to enter the cell morphology analysis device for image shooting and analysis.

[0119] In an example of the present application, the single slide loading device can move within the cell analysis system to move the test slide to the detection stage for shooting or to pick up the test slide from the single slide loading device to the detection stage for shooting by a loading device.

[0120] Specifically, the single slide loading device can be automatically ejected from the cell analysis device, for example, when the cell analysis device automatically identifies or the user triggers switching to the manual mode, the single slide loading device is automatically ejected to receive the manually put test slide for priority processing.

[0121] In addition, the single slide loading device can also be designed to be manually pulled out of the cell analysis device, for example, when switching to the manual mode is needed, the user pulls out the single slide loading device and manually puts the test slide for priority processing into the single slide loading device.

[0122] When the single slide loading device can be automatically ejected or manually pulled out, the single slide loading device can be kept in the original posture when entering and exiting, or can be flipped around a fixed shaft when entering and exiting, etc.

[0123] Further, the single slide loading device can also be fixedly arranged in the cell analysis device, and the test slide for priority processing can be inserted into the cell analysis device and placed in the single slide loading device by a mechanical clamp or manually.

[0124] In an embodiment of the present application, the single slide loading device can be a sample receiving bin separately arranged in the cell analysis device, and the sample receiving bin is used to place the test slide for priority processing.

[0125] In an embodiment of the present application, the sample receiving bin is fixedly arranged in the instrument at a position for placing a sample, and the user manually opens a closed bin door to place the test slide; or the sample receiving bin can be automatically ejected to accept the insertion module, when the user triggers an insertion request, the sample receiving bin automatically ejects a hatch, after the user places the slide, the sample receiving bin is automatically reset or manually reset by the user, and the insertion slide reading process is started.

[0126] The single-piece sample feeding device is a sample receiving bin, and the to-be-tested smear can be a single piece of glass slide; the to-be-tested smear can also be multiple pieces of glass slide, for example, a glass slide basket full of glass slides can be directly placed on the single-piece sample feeding device to transport the glass slides in the basket to the cell analysis device for shooting and analysis.

[0127] In another example of the present application, the single-piece sample feeding device is a buffer mechanism arranged in the cell analysis system to receive the to-be-tested smear manually placed therein and then transmitted to the cell analysis system through a second path.

[0128] The buffer mechanism comprises a first buffer accommodating part and a second buffer accommodating part; the first buffer accommodating part is configured to receive the to-be-tested smear moved by the automatic loading mechanism; and the second buffer accommodating part is configured to receive the to-be-tested smear manually placed in the buffer mechanism.

[0129] The buffer mechanism further comprises a first loading device configured to move the to-be-tested smear in the buffer mechanism to the detection stage;

[0130] and a second loading device configured to move the to-be-tested smear manually loaded into the cell analysis system to the detection stage.

[0131] The second loading device is configured to clamp the to-be-tested smear in the second buffer accommodating part to the detection stage; or the second loading device clamps the to-be-tested smear in the second buffer accommodating part to the first buffer accommodating part, and the first loading device moves the to-be-tested smear in the first buffer accommodating part to the detection stage.

[0132] Optionally, the buffer mechanism further comprises a guide assembly for guiding the first buffer accommodating part and / or the second buffer accommodating part to move to a loading position corresponding to the first loading device, and a driving assembly for driving the first buffer accommodating part and / or the second buffer accommodating part to reciprocally move along the guide assembly.

[0133] Further, the guide assembly is further configured to guide the second buffer accommodating part to move to outside the cell analysis system to receive the to-be-tested smear manually placed in the buffer mechanism, and the driving assembly is configured to drive the second buffer accommodating part to move along the guide assembly. The guide assembly comprises a slide rail.

[0134] In an embodiment of the present application, the cell analysis system comprises two modes of normal reading mode and queue-reading mode; the normal reading mode is adopted when the cell analysis system is in normal reading mode, and the queue-reading mode is started when there is a to-be-tested smear that needs to be processed in priority or in other cases.

[0135] The start of the priority reading mode can be triggered automatically or manually.

[0136] In an embodiment of the present application, the cell analysis system automatically triggers the priority reading mode when the smear to be tested is placed in the priority transmission device, and the smear to be tested in the priority transmission device is processed preferentially.

[0137] In addition, the priority reading mode can also be triggered automatically when the detection result of the blood analyzer is abnormal, so as to preferentially process the smear to be tested in the priority transmission device.

[0138] In addition, when the smear to be tested needs to be detected urgently, the priority reading mode can also be triggered manually, for example, a control panel is arranged on the cell morphology analysis device, and the normal mode and the priority reading mode are selected through the control panel.

[0139] When the priority reading mode is triggered, the control device prompts the smear to be tested to be placed in the priority transmission device after receiving the priority reading mode instruction.

[0140] The control device is further configured to set the shooting mode of the smear to be tested in the priority reading mode.

[0141] The control device is configured to use the self-set shooting mode, select a default mode, or select the shooting mode according to the information of the sample. The self-set shooting mode includes at least one of WBC, PLT and RBC.

[0142] The control device selects the corresponding shooting mode according to the preliminary screening result of the blood analyzer obtained by scanning the information of the smear to be tested or obtained through online information transmission. In the absence of the self-set shooting mode and the shooting mode selected according to the information of the sample, the default mode is selected.

[0143] In an embodiment of the present application, the smear prepared by the smear preparation device includes first and second opposite surfaces extending along the length direction of the smear, and a label section configured to carry label information, and the first or second surface of the smear carries the label information.

[0144] The cell analysis system further includes a smear recognition system, and the smear recognition system includes:

[0145] A smear clamping device is configured to clamp the smear to a recognition position.

[0146] A recognition device is configured to recognize the label information of the smear located on the recognition position.

[0147] a control device electrically connected with the smear clamping device and the identification device, and configured to:

[0148] control the smear clamping device to place the smear to an identification position, so that the first surface of the smear is in the identification range of the identification device;

[0149] control the identification device to identify the label information of the first surface of the smear;

[0150] if the identification device identifies the label information of the smear from the first surface of the smear, store the label information of the smear;

[0151] if the identification device does not identify the label information of the smear from the first surface of the smear, control the identification device to identify the label information of the second surface of the smear;

[0152] if the identification device identifies the label information of the smear from the second surface of the smear, store the label information of the smear.

[0153] wherein the identification device comprises a camera configured to take a photo of the label section of the smear, to perform feature recognition on the photo taken by the camera and extract the label information of the smear,

[0154] and / or the identification device comprises a barcode scanner configured to perform barcode scanning on the smear to extract the label information of the smear.

[0155] wherein the smear identification system comprises a rotating device arranged at the identification position, the rotating device being configured to accommodate the smear and being rotatable so as to drive the accommodated smear to rotate.

[0156] wherein the rotating device is configured to rotate at least 180 degrees along a predetermined rotation direction.

[0157] wherein the rotating device is configured to rotate 360 degrees along the predetermined rotation direction.

[0158] wherein the rotating device is provided with a receiving groove, and the receiving groove is open at the top so that the smear can be placed into the receiving groove from the opening.

[0159] wherein the control device is further configured to:

[0160] control the smear clamping device to clamp the smear onto the rotating device, so that the first surface of the smear is in the identification range of the identification device;

[0161] If the identification device does not identify the label information of the smear from the first surface of the smear, the control device controls the rotating device to rotate the smear accommodated therein so that the second surface of the smear is in the identification area of the identification device, so that the identification device identifies the second surface of the smear.

[0162] The smear clamping device is further configured to rotate along the axis thereof.

[0163] The control device is further configured to:

[0164] If the identification device does not identify the label information of the smear from the first surface of the smear, the control device controls the rotating device to rotate the smear accommodated therein so that the second surface of the smear is in the identification area of the identification device, so that the identification device identifies the second surface of the smear.

[0165] The smear clamping device is further configured to move in vertical and horizontal directions and is configured to place the smear on the detection workbench in a posture with the first surface or the second surface of the smear facing a preset direction when the identification device identifies the label information of the smear from the first surface or the second surface of the smear.

[0166] The smear clamping device includes a support body, a horizontal movement assembly, a vertical movement assembly, a turnover movement assembly, and a clamping assembly.

[0167] The vertical movement assembly, the turnover movement assembly, and the clamping assembly are arranged on the support body, the horizontal movement assembly is configured to drive the support body and the vertical movement assembly, the turnover movement assembly, and the clamping assembly thereon to move horizontally, the vertical movement assembly is configured to drive the clamping assembly to move vertically, and the turnover movement assembly is configured to drive the clamping assembly to turn over relative to the support body.

[0168] The identification device is further configured to identify the placement state of the smear at the identification position.

[0169] The cell analysis system further includes a smear posture adjustment apparatus including a smear storage device and a posture correction device, wherein the smear storage device is used to place the smear.

[0170] The posture correction device is used to place the smear on the smear storage device in a preset posture according to the placement state identified by the identification device.

[0171] The control device is electrically connected with the identification device and the posture correction device and is further configured to:

[0172] controlling the recognition device to recognize the first surface of the smear in the recognition position;

[0173] if the recognition device recognizes the label information of the smear from the first surface of the smear, controlling the posture correcting device to place the smear on the smear storage device in a posture with the first surface of the smear facing a first predetermined direction;

[0174] if the recognition device does not recognize the label information of the smear from the first surface of the smear, controlling the recognition device to recognize the second surface of the smear in the recognition position;

[0175] if the recognition device recognizes the label information of the smear from the second surface of the smear, controlling the posture correcting device to place the smear on the smear storage device in a posture with the second surface of the smear facing the first predetermined direction.

[0176] wherein the label information comprises identity information of the smear.

[0177] wherein the posture correcting device is further configured to change the posture of the smear in the recognition position according to the placement state recognized by the recognition device.

[0178] wherein the smear gripping device is further configured to place the smear on the smear storage device in a posture with the first surface or the second surface of the smear facing the first predetermined direction.

[0179] wherein the smear gripping device is configured to be flipped relative to the smear storage device to place the smear on the smear storage device in a posture with the first surface or the second surface of the smear facing the first predetermined direction.

[0180] wherein the smear gripping device is configured to be flipped by 90 degrees relative to the smear storage device.

[0181] wherein the recognition device comprises a first recognition component and a second recognition component arranged on two sides of the recognition position, and the control device is further configured to:

[0182] controlling the smear gripping device to move in vertical and horizontal directions to extract the smear to the recognition position, so that the first surface and the second surface of the smear are respectively in the recognition area of the first recognition component and the second recognition component;

[0183] controlling the first recognition component to recognize the first surface of the smear in the recognition position;

[0184] If the first identification component does not identify the label information of the smear from the first side of the smear, the second identification component is controlled to identify the second side of the smear in the identification position.

[0185] The control device is further configured to:

[0186] When the identification device is controlled to identify the first side or the second side of the smear, the identification device is controlled to identify the first end of the smear,

[0187] If the identification device identifies the label information of the smear from the first end of the smear, the attitude correction device is controlled to place the smear on the smear storage device in an attitude with the first side or the second side of the smear facing the first predetermined direction and the first end of the smear facing a second predetermined direction;

[0188] If the identification device does not identify the label information of the smear from the first end of the smear, the identification device is controlled to identify the second end of the smear;

[0189] If the identification device identifies the label information of the smear from the second end of the smear, the attitude correction device is controlled to place the smear on the smear storage device in an attitude with the first side or the second side of the smear facing the first predetermined direction and the second end of the smear facing the second predetermined direction.

[0190] The identification device is further configured to identify the placement state of the smear in the identification position;

[0191] The cell analysis system further comprises a smear attitude adjustment apparatus, including a smear storage device and an attitude correction device, wherein the smear storage device is used to place the smear;

[0192] The attitude correction device is used to place the smear on the smear storage device in a preset attitude according to the placement state identified by the identification device;

[0193] The control device is electrically connected with the identification device and the attitude correction device and is configured to:

[0194] The identification device is controlled to identify the first end of the smear;

[0195] If the identification device identifies the label information of the smear from the first end of the smear, the attitude correction device is controlled to place the smear on the smear storage device in an attitude with the first end of the smear facing a predetermined direction;

[0196] If the identification device does not identify the label information of the smear from the first end of the smear, the identification device is controlled to identify the second end of the smear.

[0197] If the identification device identifies the label information of the smear from the second end of the smear, the posture correction device is controlled to place the smear on the smear storage device in a posture with the second end of the smear facing the predetermined direction.

[0198] The control device is further configured to:

[0199] The smear gripping device is controlled to move in the vertical and horizontal directions to grip the smear to the identification position, so that the first end of the smear is in the identification area of the identification device.

[0200] The identification device is controlled to identify the first end of the smear.

[0201] If the identification device does not identify the label information of the smear from the first end of the smear, the smear gripping device is controlled to grip the smear from the identification position, so that the second end of the smear is in the identification area of the identification device, so that the identification device identifies the second end of the smear. Through the above arrangement, whether the to-be-tested smear is placed reversely can be detected, if the to-be-tested smear is placed reversely, posture correction is performed, if not or after correction, the to-be-tested smear is photographed and analyzed.

[0202] The cell analysis system of the present application is provided with a priority transmission device in addition to a conventional transmission device, and has a normal reading mode and a cutting-in reading mode; in the normal reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the to-be-tested smear transmitted by the conventional transmission device; in the cutting-in reading mode, the control device causes the cell morphology analysis device to perform image shooting and analysis on the to-be-tested smear transmitted by the priority transmission device, which has priority over at least one to-be-tested smear on the conventional transmission device. Through the improvement, the to-be-tested smear which needs to enter the cell morphology analysis device immediately after smear preparation can be preferentially subjected to image shooting and analysis, without queuing, thereby improving the detection efficiency of emergency samples.

[0203] Although example embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the example embodiments are only exemplary and are not intended to limit the scope of the present application. Those of ordinary skill in the art can make various changes and modifications without departing from the scope and spirit of the present application. All such changes and modifications are intended to be included within the scope of the present application as claimed in the appended claims.

[0204] Those skilled in the art can understand that the units and algorithm steps of each example described in combination with the embodiments disclosed herein can be realized in electronic hardware or in a combination of computer software and electronic hardware. Whether the functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Those skilled in the art can use different methods to implement the described functions for each specific application, but such implementation should not be considered beyond the scope of the present application.

[0205] In several embodiments provided in the present application, it should be understood that the disclosed devices and methods can be implemented in other ways. For example, the device embodiments described above are merely illustrative, for example, the division of units is only a logical function division, and actual implementation can have another division manner, for example, multiple units or components can be combined or integrated into another device, or some features can be ignored or not executed.

[0206] In the specification provided herein, a large number of specific details are described. However, it can be understood that the embodiments of the present application can be practiced without these specific details. In some examples, well-known methods, structures and techniques are not described in detail in order not to obscure the understanding of the present specification.

[0207] Similarly, it should be understood that, in order to simplify the present application and help understand one or more of the various inventive aspects, in the description of the exemplary embodiments of the present application, various features of the present application are sometimes grouped together in a single embodiment, figure, or description thereof. However, this method of the present application should not be interpreted as reflecting an intention that the claimed application requires more features than those explicitly recited in each claim. Rather, as reflected by the corresponding claims, the inventive point is that the corresponding technical problem can be solved with fewer features than all the features of a certain disclosed single embodiment. Therefore, the claims following the specific embodiments are hereby expressly incorporated into the specific embodiments, wherein each claim itself is a separate embodiment of the present application.

[0208] Those skilled in the art can understand that, except for the mutual exclusion between features, all features disclosed in the specification (including the accompanying claims, abstract and drawings) and all processes or units of any method or device disclosed in this way can be combined in any combination. Unless explicitly stated otherwise, each feature disclosed in the specification (including the accompanying claims, abstract and drawings) can be replaced by an alternative feature that provides the same, equivalent or similar purpose.

[0209] Furthermore, those skilled in the art will recognize that, while certain embodiments described herein include some, but not other, features, certain aspects of the embodiments are indeed within the scope of the application and form different embodiments, which are intended to be covered herewith. For example, in the claims, any of the claimed embodiments can be used in any combination.

[0210] Various component embodiments of the application can be implemented in hardware, or as software modules running in one or more processors, or in combinations thereof. Skilled persons will appreciate that a microprocessor or digital signal processor (DSP) can be used in practice to implement some or all of the functionality of some of the modules according to embodiments of the application. The application can also be implemented as a program for performing part or all of the methods described herein, e.g., a computer program and computer program product. Such program(s) can be stored on a computer readable medium, or can be in the form of one or more signals. Such signals can be downloaded from an Internet website, or provided on a carrier medium, or in any other form.

[0211] It is noted that the foregoing examples have been provided merely for the purposes of illustration and are not intended to limit the application as claimed. Other variations to the examples described herein will be readily appreciated by those of ordinary skill in the art and can be made without departing from the scope of the claimed application. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The application can be implemented by means of both hardware and software, and any combinations thereof. In the claims, the phrase "comprising a" or "comprising an" should not be construed to mean "consisting of only" or "consisting of." The word "comprising" is intended to mean "including but not limited to." The word "comprising" is intended to mean "including but not limited to." The word "comprising" is intended to mean "including but not limited to."

Claims

1. A cell analysis system, characterized by, The cell analysis system has a normal reading mode and a priority reading mode, and comprises a smear preparation device, a normal transmission device, a priority transmission device, a cell morphology analysis device and a control device; The smear preparation device is configured to prepare a smear to be tested containing a sample and store the prepared smear to be tested in a slide basket; The normal transmission device is configured to sequentially transmit the slide basket containing the smear to be tested from an outlet of the smear preparation device to an inlet of the cell morphology analysis device along a first path; the first path is connected to the outlet of the smear preparation device and the inlet of the cell morphology analysis device at two ends thereof; The priority transmission device comprises a priority transmission channel configured to transmit the slide basket containing the smear to be tested from the outlet of the smear preparation device to the inlet of the cell morphology analysis device along a second path different from the first path; the second path is connected to the outlet of the smear preparation device and the inlet of the cell morphology analysis device at two ends thereof; The cell morphology analysis device is configured to perform image shooting and analysis on the cells in the smear to be tested; In the normal reading mode, the control device controls the cell morphology analysis device to perform image shooting and analysis on the smears to be tested transmitted by the normal transmission device; in the priority reading mode, the control device controls the cell morphology analysis device to perform image shooting and analysis on the smears to be tested transmitted by the priority transmission device in priority to at least one smear to be tested on the normal transmission device; In the normal reading mode, the control device controls the smear preparation device to prepare smears to be tested for normal shooting and analysis, store the prepared smears to be tested in a slide basket and output the slide basket containing the smears to be tested to the normal transmission device; in the priority reading mode, the control device controls the smear preparation device to preferentially prepare priority smears, store the prepared priority smears in a slide basket and transmit the slide basket containing the priority smears from the outlet of the smear preparation device to the inlet of the cell morphology analysis device via the priority transmission channel.

2. The cell analysis system of claim 1, wherein, The control device is configured to, in the normal reading mode, control the cell morphology analysis device to receive the smears to be tested transmitted by the normal transmission device for image shooting and analysis; and in the priority reading mode, control the cell morphology analysis device to receive the smears to be tested transmitted by the priority transmission device so that the smears to be tested transmitted by the priority transmission device are given priority to perform image shooting and analysis over at least one smear to be tested on the normal transmission device.

3. The cell analysis system of claim 2, wherein, The control device is arranged in the cell morphology analysis device.

4. The cell analysis system of claim 1, wherein, The control device is arranged in the smear preparation device.

5. The cell analysis system of claim 1, wherein, The control device is configured to schedule the smears to be tested by the normal transmission device and the priority transmission device; in the normal reading mode, the control device controls the normal transmission device to transmit the smears to be tested to the cell morphology analysis device; in the priority reading mode, the control device controls the priority transmission device to transmit the smears to be tested to the cell morphology analysis device.

6. The cell analysis system of any one of claims 1 to 5, wherein, In the priority reading mode, the smears to be tested in the priority transmission device are given priority over all the smears to be tested on the normal transmission device to enter the cell morphology analysis device for image shooting and analysis.

7. The cell analysis system of any one of claims 1 to 5, wherein, The priority transmission channel is partially arranged in the smear preparation device, or partially arranged in the cell morphology analysis device, or independently arranged outside the smear preparation device and the cell morphology analysis device.

8. The cell analysis system of any one of claims 1 to 5, wherein, The normal transmission device comprises a normal transmission channel configured to sequentially transmit the smears to be tested to the cell morphology analysis device along a first path; the normal transmission channel is partially arranged in the smear preparation device, or partially arranged in the cell morphology analysis device, or independently arranged outside the smear preparation device and the cell morphology analysis device.

9. The cell analysis system of claim 8, wherein, The entrance of the priority transmission channel is in communication with the entrance of the normal transmission channel; and / or the entrances of the priority transmission channel and the normal transmission channel are both directly in communication with the exit of the smear preparation device.

10. The cell analysis system of claim 8, wherein, The priority transmission channel and the normal transmission channel are arranged side by side and are both connected to the same sample feeding channel, which is connected to the reading entrance of the cell morphology analysis device.

11. The cell analysis system of claim 1, wherein, The priority transmission device comprises a single smear feeding device arranged in the cell morphology analysis device to receive the manually placed smears to be tested.

12. The cell analysis system of claim 11, wherein, The single smear feeding device can be automatically ejected from the cell analysis device, or The single smear feeding device can be manually pulled out of the cell analysis device to receive the smears to be tested, or The single smear feeding device is fixedly arranged in the cell analysis device to receive the manually placed smears to be tested.

13. The cell analysis system of claim 11 or 12, wherein, The single smear feeding device comprises a buffer mechanism arranged in the cell analysis system, the buffer mechanism having a first buffer accommodating part and a second buffer accommodating part; the first buffer accommodating part is configured to buffer the smears to be tested; and the second buffer accommodating part is configured to receive the manually placed smears to be tested.

14. The cell analysis system of claim 12, wherein, When the smears to be tested are placed in the single smear feeding device, the cell analysis system starts the priority reading mode.

15. The cell analysis system of claim 1, wherein, The control device is configured to, when receiving the priority reading mode instruction, prompt to place the priority smears into the priority transmission device.

16. The cell analysis system of claim 15, wherein, The priority reading mode instruction is triggered by a user or automatically triggered when the detection result of the blood analyzer is abnormal.

17. The cell analysis system of claim 16, wherein, The control device is further configured to set the shooting mode of the smears to be tested in the priority reading mode.

18. The cell analysis system of claim 17, wherein, The control device is configured to use the autonomously set shooting mode, or select a default mode, or select a shooting mode according to the information of the sample.

19. The cell analysis system of claim 1, wherein, The cell morphology analysis device is provided with a control panel configured to select the normal reading mode and the priority reading mode through the control panel.

20. The cell analysis system of any one of claims 1 to 5, wherein, The conventional transmission device has the function of queuing and buffering, while the priority transmission channel does not have the function of queuing and buffering.

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