Ophthalmic optical coherence tomography with multiple resolutions

Abstract

Systems and methods for performing ophthalmic optical coherence tomography with multiple resolutions are disclosed. In some embodiments, a system includes a light source, an output lens, and a set of optical components between the light source and the output lens, the set of optical components including an afocal zoom telescope. The set of optical components is adapted to provide imaging at a first field of view having a first resolution and at a second field of view having a second resolution, where the first field of view is wider than the second field of view and the second resolution is higher than the first resolution. Methods of performing ophthalmic optical coherence tomography with one or more resolutions can be performed using one or more of the systems described herein.

Description

Technical Field

[0001] This disclosure relates to systems and methods associated with ophthalmic optical coherence tomography. Background Technology

[0002] Optical coherence tomography (OCT) imaging is a widely used ophthalmic imaging technique. OCT is a non-invasive diagnostic procedure that provides in vivo cross-sectional subepidermal imaging across tissue layers. OCT has been used for both posterior segment imaging (e.g., examining the retina) and anterior segment imaging (e.g., examining the lens and / or cornea). OCT can help ophthalmologists diagnose eye problems, model the eye, and provide preoperative information for surgery.

[0003] There is a need to improve the systems and methods of ophthalmic OCT. Summary of the Invention

[0004] This disclosure relates to systems and methods for performing ophthalmic optical coherence tomography at multiple resolutions.

[0005] In some embodiments, the system includes a light source, an output lens, and an optical assembly between the light source and the output lens, the optical assembly including a focal-shift zoom telescope. The optical assembly is adapted to provide imaging in a first field of view having a first resolution and in a second field of view having a second resolution, wherein the first field of view is wider than the second field of view and the second resolution is higher than the first resolution. The optical assembly is adapted to provide imaging at least in the first field of view by passing light emitted from the light source through the focal-shift zoom telescope.

[0006] In some embodiments, the optical component group may have a first configuration providing a first field of view with the first resolution and a second configuration providing a second field of view with the second resolution.

[0007] In some embodiments, the afocal zoom telescope includes a zoom lens, wherein the position of the zoom lens is movable between a first position and a second position, wherein when the zoom lens is in its first position, the optical component group is in its first configuration, and wherein when the zoom lens is in its second position, the optical component group is in its second configuration.

[0008] In some embodiments, the focal-free zoom telescope is movable between a first position and a second position, wherein when the focal-free zoom telescope is in its first position, the optical component assembly is in its first configuration, and wherein when the focal-free zoom telescope is in its second position, the optical component assembly is in its second configuration. In some embodiments, when the focal-free zoom telescope is in its first position, the system is configured such that light emitted from the light source passes through the focal-free zoom telescope, and when the focal-free zoom telescope is in its second position, the system is configured such that light emitted from the light source does not pass through the focal-free zoom telescope. The focal-free zoom telescope can be moved by rotation and / or translation of the focal-free zoom telescope.

[0009] In some embodiments, when the optical component assembly is in its first configuration, the system is configured such that light emitted from the light source propagates along a first optical path, and when the optical component assembly is in its second configuration, the system is configured such that light emitted from the light source propagates along a second optical path. The first optical path may be a path passing through the afocal zoom telescope, and the second optical path may be a path that does not pass through the afocal zoom telescope or passes through different afocal zoom telescopes.

[0010] In some embodiments, the optical component assembly may include a first reflector at an input end of the optical component assembly, wherein the first reflector is movable between a first position and a second position, wherein when the first reflector is in its first position, the system is configured such that light emitted from the light source propagates along the first optical path, and wherein when the first reflector is in its second position, the system is configured such that light emitted from the light source propagates along the second optical path.

[0011] In some embodiments, the optical component group may include a polarizing optics device at the input end of the optical component group, a polarization rotation device in the second optical path, and a polarization beam splitter at the output end of the optical component group.

[0012] In some embodiments, the optical component group may further include a second reflector at the output end of the optical component group.

[0013] In some embodiments, the optical component group may further include a beam splitter at the output end of the optical component group.

[0014] In some embodiments, the optical component group may further include a beam splitter, a first shutter and a second shutter at the input end of the optical component group, wherein, when the optical component group is in its first configuration, the second shutter prevents light emitted from the light source from propagating through the second optical path, and wherein, when the optical component group is in its second configuration, the first shutter prevents light emitted from the light source from propagating through the first optical path.

[0015] In some embodiments, the optical component group may further include a polarization rotation device and a polarization beam splitter at the input end of the optical component group, and a polarization beam splitter at the output end of the optical components group.

[0016] In some embodiments, the optical component assembly may further include an input polarization beam splitter at the input end of the optical component assembly, wherein the input polarization beam splitter is adapted to separate the incident light such that light of a first polarization propagates along a first optical path passing through the afocal zoom telescope, and light of a second polarization propagates along a second optical path not passing through the afocal zoom telescope. The first polarization may be one of TE or TM polarization and the second polarization may be the other of TE or TM polarization. The optical component assembly may further include an output polarization beam splitter at the output end of the optical component assembly. The system may further include an interferometer having a detector adapted to select each of the first polarization and the second polarization.

[0017] In some embodiments, a method of performing ophthalmic optical coherence tomography at one or more resolutions includes: emitting light from a light source, passing the light from the light source through an optical assembly in a first field of view having a first resolution, and passing the light from the light source through the optical assembly in a second field of view having a second resolution. The first field of view may be wider than the second field of view, and the second resolution may be higher than the first resolution. The step of passing the light from the light source through the optical assembly in the first field of view having the first resolution may include passing the light emitted from the light source through an afocal zoom telescope.

[0018] In some embodiments, one or more systems described herein can be used to perform ophthalmic optical coherence tomography at one or more resolutions. Attached Figure Description

[0019] The accompanying drawings illustrate implementations of the systems and methods disclosed herein and, together with the specification, serve to explain the principles underlying this disclosure.

[0020] Figure 1A and Figure 1B An example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0021] Figure 2A and Figure 2B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0022] Figure 3A and Figure 3B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0023] Figure 4A and Figure 4B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0024] Figure 5A and Figure 5B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0025] Figure 6A and Figure 6B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0026] Figure 7A and Figure 7B Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0027] Figure 8 Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0028] Figure 9 Another example embodiment of a system for performing ophthalmic optical coherence tomography at multiple resolutions is shown.

[0029] The accompanying drawings can be better understood by referring to the following detailed description. Detailed Implementation

[0030] For the purpose of facilitating an understanding of the principles of this disclosure, reference will now be made to the embodiments illustrated in the accompanying drawings, and these embodiments will be described using specific language. However, it should be understood that this is not intended to limit the scope of this disclosure. Those skilled in the art to which this disclosure pertains will generally be fully capable of conceiving of any changes and further modifications to the described apparatus, instruments, and methods, as well as any further applications of the principles of this disclosure. In particular, features, components, and / or steps described with respect to one embodiment may be combined with features, components, and / or steps described with respect to other embodiments of this disclosure. For simplicity, in some cases, the same reference numerals are used in all the drawings to refer to the same or similar components.

[0031] Figures 1A to 9 The example embodiment shown is an example of a system for performing ophthalmic optical coherence tomography (OCT) at multiple resolutions. The system directs light to point 10 in the eye to perform OCT on the tissue to be examined. OCT can be performed for posterior segment imaging (e.g., examining the retina) and / or anterior segment imaging (e.g., examining the lens and / or cornea).

[0032] Figures 1A to 9 In each of the embodiments shown, the system is adapted to provide imaging in multiple fields of view, each with a different resolution. Each of these illustrated systems is adapted to provide imaging in a first relatively large or wide field of view having a first relatively low resolution and in a second relatively small or narrow field of view having a second relatively high resolution.

[0033] Figure 1A and Figure 1B An example embodiment of a system 100 for performing ophthalmic OCT at multiple resolutions is shown. System 100 includes a light source 102, an output lens 198, and an optical assembly 110 between the light source 102 and the output lens 198. System 100 may include a collimating lens 122, a two-dimensional (2D) scanner 124, and a beam expander 126, as shown. The light source 102 may be a suitable optical fiber. The optical assembly 110 includes an afocal zoom telescope 116. The optical assembly 110 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 1A (as shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 1B (As shown) provides imaging.

[0034] exist Figure 1A and Figure 1B In the example, the optical component group 110 has a first configuration (such as...) Figure 1A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 1BAs shown), it provides a second field of view with a second resolution. The afocal zoom telescope 116 includes a zoom lens 118, wherein the position of the zoom lens 118 is movable between a first position and a second position. When the zoom lens 118 is in its first position, the optical component group 110 is in its first configuration, and when the zoom lens 118 is in its second position, the optical component group 110 is in its second configuration.

[0035] The zoom lens 118, under electronic control, allows the operator to quickly and efficiently switch between a first configuration and a second configuration. The movement of the zoom lens 118 can occur without requiring repositioning relative to the patient repositioning system 100.

[0036] Figure 2A and Figure 2B Another example embodiment of a system 200 for performing ophthalmic OCT at multiple resolutions is shown. System 200 includes a light source 202, an output lens 298, and an optical assembly 210 between the light source 202 and the output lens 298. System 200 may include a collimating lens 222, a two-dimensional (2D) scanner 224, and a beam expander 226, as shown. The light source 202 may be a suitable optical fiber. The optical assembly 210 includes an afocal zoom telescope 216. The optical assembly 210 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 2A (as shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 2B (As shown) provides imaging.

[0037] exist Figure 2A and Figure 2B In the example, the optical component group 210 has a first configuration (such as...) Figure 2A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 2B (As shown), it provides a second field of view with a second resolution. In this example embodiment, the afocal zoom telescope 216 can provide a second field of view as shown in the example. Figure 2A The first position shown is as follows Figure 2B The telescope moves between the second positions shown. When the afocal zoom telescope 216 is in the position shown... Figure 2A When shown in its first position, the optical component assembly 210 is in its first configuration. When the afocal zoom telescope 216 is in the position shown... Figure 2B When shown in its second position, the optical component assembly 210 is in its second configuration. When the afocal zoom telescope 216 is in such a position... Figure 2A In its first position, as shown, system 200 is configured such that light emitted from light source 202 passes through the afocal zoom telescope 216, providing a relatively large field of view. When the afocal zoom telescope 216 is in such a position... Figure 2BIn its second position, as shown, system 200 is configured such that light emitted from light source 202 does not pass through afocal zoom telescope 216, thereby providing relatively high resolution.

[0038] The focal-free zoom telescope 216 can be moved between its first and second positions in any suitable manner. For example, the focal-free zoom telescope 216 can be moved between its first and second positions by rotation and / or translation. The focal-free zoom telescope 216 can be electronically controlled, allowing the operator to quickly and efficiently switch between the first and second configurations. The movement of the focal-free zoom telescope 216 can occur without requiring repositioning relative to the patient repositioning system 200.

[0039] Figure 3A and Figure 3B Another example embodiment of a system 300 for performing ophthalmic OCT at multiple resolutions is shown. System 300 includes a light source 302, an output lens 398, and an optical assembly 310 between the light source 302 and the output lens 398. System 300 may include a collimating lens 322, a two-dimensional (2D) scanner 324, and a beam expander 326, as shown. The light source 302 may be a suitable optical fiber. The optical assembly 310 includes an afocal zoom telescope 316. The optical assembly 310 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 3A (As shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 3B (As shown) provides imaging.

[0040] exist Figure 3A and Figure 3B In the example, the optical component group 310 has a first configuration (such as...) Figure 3A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 3B (As shown), it provides a second field of view with a second resolution. When the optical component assembly 310 is in the position as shown... Figure 3A In its first configuration, as shown, system 300 is configured such that light emitted from light source 302 propagates along first optical path 370. When the optical component assembly 310 is in such a state... Figure 3B In its second configuration, as shown, system 300 is configured such that light emitted from light source 302 propagates along a second optical path 380. In the example shown, the first optical path 370 passes through the afocal zoom telescope 316, while the second optical path 380 does not pass through the afocal zoom telescope 316.

[0041] In an alternative embodiment of the example shown herein, the second optical path passes through a focusless zoom telescope, while the first optical path does not. In other alternative embodiments of the example shown herein, both the first and second optical paths pass through one or more focusless zoom telescopes.

[0042] exist Figure 3A and Figure 3B In the example, the optical component assembly 310 further includes a first reflecting mirror 330 at the input end 312 of the optical component assembly 310. The first reflecting mirror 330 may be, for example... Figure 3A The first position shown is as follows Figure 3B The first reflector 330 moves between the second positions shown. Figure 3A When the first reflector 330 is in its first position as shown, the system 300 is configured such that light emitted from the light source 302 propagates along the first optical path 370. Figure 3B When in its second position as shown, the system 300 is configured such that light emitted from the light source 302 propagates along the second optical path 380.

[0043] exist Figure 3A and Figure 3B In the example shown, the first position of the first reflector 330 is a position outside the path of the light emitted from the light source 302, thereby allowing the light emitted from the light source 302 to propagate along the first optical path 370. The second position of the first reflector 330 is a position where the first reflector 330 is inserted into the path of the light emitted from the light source 302, thereby changing the direction of the light emitted from the light source 302 to propagate along the second optical path 380. In an alternative embodiment, the first position of the first reflector may be a position where the first reflector is inserted into the path of the light emitted from the light source, thereby changing the direction of the light emitted from the light source, and the second position of the first reflector may be a position where the first reflector is outside the path of the light emitted from the light source, thereby not changing the direction of the light emitted from the light source.

[0044] exist Figure 3A and Figure 3B In the path of light redirected by the first reflector 330, the system 300 further includes additional reflectors 332 and 334 for redirecting light back toward a beam splitter 350 located at the output end 314 of the optical component assembly 310. The beam splitter 350 allows light from the first optical path 370 to pass toward the output lens 398, and also reflects light from the second optical path 380 toward the output lens 398. Thus, the beam splitter 350 is present in both the first optical path 370 and the second optical path 380.

[0045] System 300 further includes a compensating optics 360 on the path of light redirected by the first reflector 330. The compensating optics 360 compensates for the redirection of the beam path.

[0046] The first reflector 330 can be electronically controlled, allowing the operator to quickly and efficiently switch between a first configuration and a second configuration. The movement of the first reflector 330 can occur without requiring repositioning relative to the patient repositioning system 300.

[0047] Figure 4A and Figure 4B Another example embodiment of a system 400 for performing ophthalmic OCT at multiple resolutions is shown. System 400 includes a light source 402, an output lens 498, and an optical assembly 410 between the light source 402 and the output lens 498. System 400 may include a collimating lens 422, a two-dimensional (2D) scanner 424, and a beam expander 426, as shown. The light source 402 may be a suitable optical fiber. The optical assembly 410 includes an afocal zoom telescope 416. The optical assembly 410 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 4A (As shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 4B (As shown) provides imaging.

[0048] exist Figure 4A and Figure 4B In the example, the optical component group 410 has a first configuration (such as...) Figure 4A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 4B As shown), it provides a second field of view with a second resolution. When the optical component assembly 410 is in the position as shown... Figure 4A In its first configuration, as shown, system 400 is configured such that light emitted from light source 402 propagates along first optical path 470. When the optical component assembly 410 is in such a state... Figure 4B In its second configuration, as shown, system 400 is configured such that light emitted from light source 402 propagates along a second optical path 480. In the example shown, the first optical path 470 passes through the focal-free zoom telescope 416, while the second optical path 480 does not. As mentioned above, alternative configurations are possible, such as where the second optical path passes through the focal-free zoom telescope while the first optical path does not, or where both the first and second optical paths pass through one or more focal-free zoom telescopes.

[0049] Similar to Figure 3A and Figure 3B In the example, Figure 4A and Figure 4BIn the example, the optical component assembly 410 further includes a first reflector 430 at the input end 412 of the optical component assembly 410. The first reflector 430 may be, for example... Figure 4A The first position shown is as follows Figure 4B The first reflector 430 moves between the second positions shown. Figure 4A When the first reflector 430 is in its first position as shown, the system 400 is configured such that light emitted from the light source 402 propagates along the first optical path 470. Figure 4B When the system is in its second position as shown, the system 400 is configured such that light emitted from the light source 402 propagates along the second optical path 480.

[0050] exist Figure 4A and Figure 4B In the example shown, the first position of the first reflector 430 is a position outside the path of the light emitted from the light source 402, thereby allowing the light emitted from the light source 402 to propagate along the first optical path 470. The second position of the first reflector 430 is a position where the first reflector 430 is inserted into the path of the light emitted from the light source 402, thereby changing the direction of the light emitted from the light source 402 to propagate along the second optical path 480. In an alternative embodiment, the first position of the first reflector may be a position where the first reflector is inserted into the path of the light emitted from the light source, thereby changing the direction of the light emitted from the light source, and the second position of the first reflector may be a position where the first reflector is outside the path of the light emitted from the light source, thereby not changing the direction of the light emitted from the light source.

[0051] exist Figure 4A and Figure 4B In the path of light redirected by the first reflector 430, system 400 further includes additional reflectors 432 and 434 for redirecting the light back toward a beam splitter 450 located at the output end 414 of the optical component assembly 410. System 400 further includes a compensation optics device 460 on the path of light redirected by the first reflector 430. The compensation optics device 460 compensates for the redirection of the beam path.

[0052] exist Figure 4A and Figure 4BIn the example, the optical assembly 410 further includes a polarizing optics device 428 at its input end 412 before the first reflector 430. The polarizing optics device 428 is adapted to polarize the beam (actively or passively) before the first reflector 430. The optical assembly 410 further includes a polarization rotation device, such as a half-wave plate 482 on the second optical path 480, before the beam splitter 450 at its output end 414. The beam splitter 450 is a polarization beam splitter that guides light of a first polarization through the first optical path 470 and reflects light of a second polarization through the second optical path 480. In this way, the total power flux can be optimized.

[0053] The first reflector 430 can be electronically controlled, allowing the operator to quickly and efficiently switch between a first configuration and a second configuration. The movement of the first reflector 430 can occur without requiring repositioning relative to the patient repositioning system 400.

[0054] Figure 5A and Figure 5B Another example embodiment of a system 500 for performing ophthalmic OCT at multiple resolutions is shown. System 500 is similar to... Figure 3A and Figure 3B The system 300 shown differs in that it has a second mirror 550 at the output end 514 of the optical component assembly instead of a beam splitter 350. System 500 includes a light source 502, an output lens 598, and an optical component assembly 510 between the light source 502 and the output lens 598. System 500 may include a collimating lens 522, a two-dimensional (2D) scanner 524, and a beam expander 526, as shown. The light source 502 may be a suitable optical fiber. The optical component assembly 510 includes an afocal zoom telescope 516. The optical component assembly 510 is adapted to provide a first large field of view with a first lower resolution (e.g., ...). Figure 5A (as shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 5B (As shown) provides imaging.

[0055] exist Figure 5A and Figure 5B In the example, the optical component group 510 has a first configuration (such as...) Figure 5A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 5B (As shown), it provides a second field of view with a second resolution. When the optical component assembly 510 is in the position as shown... Figure 5A In its first configuration, as shown, system 500 is configured such that light emitted from light source 502 propagates along first optical path 570. When the optical component assembly 510 is in such a state... Figure 5BIn its second configuration, as shown, system 500 is configured such that light emitted from light source 502 propagates along a second optical path 580. In the example shown, the first optical path 570 passes through the focal-free zoom telescope 516, while the second optical path 580 does not. As mentioned above, alternative configurations are possible, such as where the second optical path passes through the focal-free zoom telescope while the first optical path does not, or where both the first and second optical paths pass through one or more focal-free zoom telescopes.

[0056] Similar to Figure 3A and Figure 3B In the example, Figure 5A and Figure 5B In the example, the optical component assembly 510 further includes a first reflector 530 at the input end 512 of the optical component assembly 510. The first reflector 530 may be, for example... Figure 5A The first position shown is as follows Figure 5B The first reflector 530 moves between the second positions shown. Figure 5A When the first reflector 530 is in its first position as shown, the system 500 is configured such that light emitted from the light source 502 propagates along the first optical path 570. Figure 5B When the system is in its second position as shown, the system 500 is configured such that light emitted from the light source 502 propagates along the second optical path 580.

[0057] exist Figure 5A and Figure 5B In the path of light redirected by the first reflector 530, system 500 further includes additional reflectors 532 and 534 for redirecting the light back toward a second reflector 550 located at the output end 514 of the optical component assembly 510. System 500 further includes a compensation optics device 560 on the path of light redirected by the first reflector 530. The compensation optics device 560 compensates for the redirection of the beam path.

[0058] Like the first reflector 530, the second reflector 550 can be used as... Figure 5A The first position shown is as follows Figure 5B The first reflector 530 moves between the second positions shown. Figure 5A When the first reflector 530 is in its first position as shown, the second reflector 550 is also in its first position, and the system 500 is configured such that light emitted from the light source 502 propagates along the first optical path 570. When the first reflector 530 is in the first position as shown, the second reflector 550 is also in its first position, and the system 500 is configured such that light emitted from the light source 502 propagates along the first optical path Figure 5B When the second position is shown, the second reflector 550 is also in its second position, and the system 500 is configured such that light emitted from the light source 502 propagates along the second optical path 580.

[0059] exist Figure 5A and Figure 5B In the example shown, the first position of the first reflector 530 and the second reflector 550 is a position where the first reflector 530 and the second reflector 550 are outside the path of the light emitted from the light source 502, thereby allowing the light emitted from the light source 502 to propagate along the first optical path 570. The second position of the first reflector 530 and the second reflector 550 is a position where the first reflector 530 and the second reflector 550 are inserted into the path of the light emitted from the light source 502, thereby changing the direction of the light emitted from the light source 502 to propagate along the second optical path 580. In an alternative embodiment, the first position of the first and second reflectors can be a position where the first and second reflectors are inserted into the path of the light emitted from the light source, thereby changing the direction of the light emitted from the light source. The second position of the first and second reflectors can be a position where the first and second reflectors are outside the path of the light emitted from the light source, thereby not changing the direction of the light emitted from the light source. In an alternative embodiment, in the first position, the first reflector can be in the optical path while the second reflector is outside the optical path, and in the second position, the first reflector can be outside the optical path while the second reflector is in the optical path.

[0060] The first reflector 530 and the second reflector 550 can be electronically controlled, allowing the operator to quickly and efficiently switch between a first configuration and a second configuration. The movement of the first reflector 530 and the second reflector 550 can occur without requiring repositioning relative to the patient repositioning system 500.

[0061] Figure 6A and Figure 6B Another example embodiment of a system 600 for performing ophthalmic OCT at multiple resolutions is shown. System 600 includes a light source 602, an output lens 698, and an optical assembly 610 between the light source 602 and the output lens 698. System 600 may include a collimating lens 622, a two-dimensional (2D) scanner 624, and a beam expander 626, as shown. The light source 602 may be a suitable optical fiber. The optical assembly 610 includes an afocal zoom telescope 616. The optical assembly 610 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 6A (as shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 6B (As shown) provides imaging.

[0062] exist Figure 6A and Figure 6B In the example, the optical component group 610 has a first configuration (such as...) Figure 6A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 6B As shown), it provides a second field of view with a second resolution. When the optical component assembly 610 is in the position as shown... Figure 6AIn its first configuration, as shown, system 600 is configured such that light emitted from light source 602 propagates along first optical path 670. When the optical component assembly 610 is in such a state... Figure 6B In its second configuration, as shown, system 600 is configured such that light emitted from light source 602 propagates along a second optical path 680. In the example shown, the first optical path 670 passes through the focal-free zoom telescope 616, while the second optical path 680 does not. As described above, alternative configurations are possible, such as where the second optical path passes through the focal-free zoom telescope while the first optical path does not, or where both the first and second optical paths pass through one or more focal-free zoom telescopes.

[0063] exist Figure 6A and Figure 6B In the example, the optical component assembly 610 further includes a first beam splitter 630 at its input end 612. The first beam splitter 630 separates the incident beam, allowing light emitted from the light source 602 to propagate in both the direction of the first optical path 670 and the direction of the second optical path 680. The optical component assembly 610 further includes a second beam splitter 650 at its output end 614. The second beam splitter 650 is located both in the first optical path 670 and the second optical path 680.

[0064] The optical assembly 610 further includes a first shutter 636 and a second shutter 638 positioned after the first beam splitter 630 at the input end 612 of the optical assembly 610. The first shutter 636 is selectively operable to allow or block light propagation through the first optical path 670. The second shutter 638 is selectively operable to allow or block light propagation through the second optical path 680. When the optical assembly 610 is in its first configuration, the second shutter 638 prevents light emitted from the light source 602 from propagating through the second optical path 680 and also prevents light emitted from the light source 602 from propagating through the first optical path 670. When the optical assembly 610 is in its second configuration, the first shutter 636 prevents light emitted from the light source 602 from propagating through the first optical path and also prevents light emitted from the light source 602 from propagating through the second optical path 680.

[0065] exist Figure 6A and Figure 6B In the path of the light reflected by the first beam splitter 630, system 600 further includes mirrors 632 and 634 for redirecting the light back toward a second beam splitter 650 located at the output end 614 of the optical component assembly 610. System 600 further includes a compensation optics 660 on the path of the light reflected by the first beam splitter 630. The compensation optics 660 compensates for the redirection of the beam path.

[0066] The first shutter 636 and the second shutter 638 can be electronically controlled, allowing the operator to quickly and efficiently switch between the first and second configurations. The movement of the first shutter 636 and the second shutter 638 can occur without requiring repositioning relative to the patient system 600.

[0067] Figure 7A and Figure 7B Another example embodiment of a system 700 for performing ophthalmic OCT at multiple resolutions is shown. System 700 includes a light source 702, an output lens 798, and an optical assembly 710 between the light source 702 and the output lens 798. System 700 may include a collimating lens 722, a two-dimensional (2D) scanner 724, and a beam expander 726, as shown. The light source 702 may be a suitable optical fiber. The optical assembly 710 includes an afocal zoom telescope 716. The optical assembly 710 is adapted to provide a first larger field of view (e.g., with a first lower resolution) at a first lower resolution. Figure 7A (As shown) provides imaging and a second smaller field of view with a second higher resolution (e.g.) Figure 7B (As shown) provides imaging.

[0068] exist Figure 7A and Figure 7B In the example, the optical component group 710 has a first configuration (such as...) Figure 7A As shown), it provides a first field of view with a first resolution, and a second configuration (such as...). Figure 7B As shown), it provides a second field of view with a second resolution. When the optical component assembly 710 is in the position as shown... Figure 7A In its first configuration, as shown, system 700 is configured such that light emitted from light source 702 propagates along first optical path 770. When the optical component assembly 710 is in such a state... Figure 7B In the second configuration shown, system 700 is configured such that light emitted from light source 702 propagates along a second optical path 780. In the example shown, the first optical path 770 passes through the focal-free zoom telescope 716, while the second optical path 780 does not pass through the focal-free zoom telescope 716. As mentioned above, alternative configurations are possible, for example, where the second optical path passes through the focal-free zoom telescope while the first optical path does not, or where both the first and second optical paths pass through one or more focal-free zoom telescopes.

[0069] exist Figure 7A and Figure 7BIn the example, the optical assembly 710 further includes a polarizing optics 736 and a polarization rotation device, such as a half-wave plate 738 located at the input end 712 of the optical assembly 710. The polarizing optics 736 is adapted to polarize the beam (actively or passively) before the polarization rotation device 738 and the polarization beam splitter 730. As an alternative to the polarizing optics 736, a light source emitting polarized light can be used. The polarization rotation device 738 is adapted to move between two positions: one where the polarization of the incident light is rotated, and another where the polarization of the incident light is not rotated (or rotated by a different amount). The polarization beam splitter 730 guides light of the first polarization through the first optical path 770 and reflects light of the second polarization through the second optical path 780. The optical assembly 710 further includes a second polarization beam splitter 750 at the output end 714 of the optical assembly 710. The second polarization beam splitter 750 is located both in the first optical path 770 and the second optical path 780. In this way, the total power flux can be optimized.

[0070] exist Figure 7A and Figure 7B In the path of the light reflected by the first beam splitter 730, system 700 further includes mirrors 732 and 734 for redirecting the light back toward a second beam splitter 750 located at the output end 714 of the optical component assembly 710. System 700 further includes a compensation optics 760 on the path of the light reflected by the first beam splitter 730. The compensation optics 760 compensates for the redirection of the beam path.

[0071] The polarization rotation device 738 can be moved between positions in any suitable manner. For example, the polarization rotation device can be moved from, for example, Figure 7A The first position rotation is shown, wherein the polarization of the incident light does not rotate and is therefore allowed to propagate through the first optical path 770 by the first beam splitter 730, and from... Figure 7B The second position rotation is shown, wherein the polarization of the incident light is rotated and thus reflected by the first beam splitter 730 to propagate through the second optical path 780. The polarization rotation device 738 can be rotated by any suitable angle. Alternatively, the polarization rotation device 738 can be moved by translating between a position on the optical path and a position outside the optical path.

[0072] The polarization rotation device 738, under electronic control, allows the operator to quickly and efficiently switch between a first configuration and a second configuration. The movement of the polarization rotation device 738 can occur without requiring repositioning relative to the patient repositioning system 700.

[0073] Figure 8Another example embodiment of a system 800 for performing ophthalmic OCT at multiple resolutions is shown. System 800 includes a light source 802, an output lens 898, and an optical assembly 810 between the light source 802 and the output lens 898. System 800 may include a collimating lens 822, a two-dimensional (2D) scanner 824, and a beam expander 826, as shown. The light source 802 may be a suitable optical fiber. The optical assembly 810 includes afocal zoom telescope 816. The optical assembly 810 is adapted to provide imaging in a first larger field of view having a first lower resolution and in a second smaller field of view having a second higher resolution.

[0074] exist Figure 8 In the example, the optical component assembly 810 further includes a polarization device 828 and an input polarization beam splitter 830 at the input end 812 of the optical component assembly 810. The polarization device 828 (actively or passively) polarizes light into multiple polarizations, such as allowing TE and TM polarization. The input polarization beam splitter 830 is adapted to separate the incident light such that light of a first polarization propagates along a first optical path 870 passing through the afocal zoom telescope 816, and light of a second polarization propagates along a second optical path 880 not passing through the afocal zoom telescope. The first polarization can be one of TE or TM polarization and the second polarization can be the other of TE or TM polarization. The optical component assembly 810 further includes an output polarization beam splitter 850 at the output end 814 of the optical component assembly 810. The output polarization beam splitter 850 is on both the first optical path 870 and the second optical path 880. Figure 8 As shown, system 800 further includes interferometer 890 with detectors adapted to select each of the first polarization and the second polarization.

[0075] exist Figure 8 In the path of the light reflected by the first beam splitter 830, system 800 further includes mirrors 832 and 834 for redirecting the light back toward a second beam splitter 850 located at the output end 814 of the optical component assembly 810. System 800 further includes a compensation optics device 860 on the path of the light reflected by the first beam splitter 830. The compensation optics device 860 compensates for the redirection of the beam path.

[0076] Figure 8 The system 800 allows for simultaneous OCT scanning with a larger field of view at lower resolution and a smaller field of view at higher resolution. The detectors in the interferometer 890 select different polarizations to handle different fields of view and resolutions.

[0077] Figure 9Another example embodiment of a system 900 for performing ophthalmic OCT at multiple resolutions is shown. System 900 is similar to system 800, except that system 900 does not have a polarization device 828 but instead includes two light sources 902, 904. Light source 902 emits light with a first polarization (e.g., TE or TM polarization), and light source 904 emits light with a second polarization (e.g., another of TE or TM polarization). System 900 further includes an output lens 998 and an optical assembly 910 between the light sources 902, 904 and the output lens 998. System 900 may include a collimating lens 922, a two-dimensional (2D) scanner 924, and a beam expander 926, as shown. Light sources 902 and 904 may be suitable optical fibers. A beam splitter 906 may be used to bring light from light sources 902 and 904 into a common path. The optical assembly 910 includes afocal zoom telescope 916. The optical component assembly 910 is adapted to provide imaging in a first larger field of view with a first lower resolution and in a second smaller field of view with a second higher resolution.

[0078] picture Figure 8 Similar to the example, in Figure 9 In the example, the optical component assembly 910 further includes an input polarization beam splitter 930 at its input end 912. The input polarization beam splitter 930 is adapted to separate the incident light such that light of a first polarization propagates along a first optical path 970 passing through the afocal zoom telescope 916, and light of a second polarization propagates along a second optical path 980 that does not pass through the afocal zoom telescope. The first polarization can be one of TE or TM polarization and the second polarization can be the other of TE or TM polarization. The optical component assembly 910 further includes an output polarization beam splitter 950 at its output end 914. The output polarization beam splitter 950 is on both the first optical path 970 and the second optical path 980. Figure 9 As shown, system 900 further includes interferometer 990 with detectors adapted to select each of the first polarization and the second polarization.

[0079] like Figure 8 As shown, in Figure 9 In the path of the light reflected by the first beam splitter 930, system 900 further includes mirrors 932 and 934 for redirecting the light back toward a second beam splitter 950 located at the output end 914 of the optical component assembly 910. System 900 further includes a compensation optics 960 on the path of the light reflected by the first beam splitter 930. The compensation optics 960 compensates for the redirection of the beam path.

[0080] Figure 9The system 900 allows for simultaneous OCT scanning with a larger field of view at lower resolution and a smaller field of view at higher resolution. The detectors in the interferometer 990 select different polarizations to handle different fields of view and resolutions.

[0081] A method for performing ophthalmic OCT can be performed using one or more systems described herein. The method includes: emitting light from one or more light sources; passing the light from the light sources(s) through an optical assembly at a first field of view having a first resolution; and passing the light from the light sources through the optical assembly at a second field of view having a second resolution. The first field of view is wider than the second field of view, and the second resolution is higher than the first resolution. The step of passing the light from the light sources through the optical assembly at the first field of view having the first resolution includes passing the light emitted from the light sources through an afocal zoom telescope.

[0082] Those skilled in the art will understand from this disclosure that it provides a system for providing ophthalmic OCT at multiple resolutions, at least one of which is a low resolution with a large field of view and at least one of which is a high resolution with a small field of view. For example, the low resolution could be a lateral resolution of approximately 20 μm with a field of view of approximately + / - 10 mm at the corneal plane of the eye, and the high resolution could be a lateral resolution of approximately 5 μm with a field of view of approximately + / - 4 mm at the corneal plane of the eye. The system may include a relatively small beam diameter, allowing for high scanning speeds without being excessively affected by eye movements.

[0083] Those skilled in the art will understand from this disclosure that it implements a system for providing ophthalmic OCT with multiple resolutions that change rapidly between resolutions. In some embodiments, components move rapidly between configurations. This movement can be electronically controlled and automated. In other embodiments, the system captures two resolutions simultaneously without moving components. Associated optics can be integrated into the interior of the optical head to maintain cleanliness and alignment and prevent damage during operation. In some embodiments, the system described herein can also allow for maintaining a relatively long working distance, such as approximately 100 mm, for patient comfort. In some embodiments, the system described herein can avoid the need for external devices that require manual insertion and proximity to the patient's eye.

[0084] Those skilled in the art will understand that the embodiments covered by this disclosure are not limited to the specific exemplary embodiments described above. In this regard, although several illustrative embodiments have been shown and described, various modifications, alterations, and substitutions are contemplated in the foregoing disclosure. It should be understood that such changes can be made to the foregoing without departing from the scope of this disclosure. Therefore, it should be understood that the appended claims should be interpreted broadly and in accordance with the content of this disclosure.

Claims

1. A system for performing ophthalmic optical coherence tomography, the system comprising: light source; Output lens; as well as An optical component assembly between the light source and the output lens, the optical component assembly including a focusless zoom telescope; The optical component assembly is adapted to provide imaging in a first field of view having a first resolution and in a second field of view having a second resolution; In this context, both the first field of view and the second field of view point to the same tissue to be examined. Wherein, the first field of view is wider than the second field of view, and the second resolution is higher than the first resolution; The optical component group has a first configuration providing a first field of view with the first resolution and a second configuration providing a second field of view with the second resolution; The focal-free zoom telescope is movable between a first position and a second position. When the focal-free zoom telescope is in its first position, the optical component group is in its first configuration. When the focal-free zoom telescope is in its second position, the optical component group is in its second configuration. Wherein, when the afocal zoom telescope is in its first position, the system is configured such that light emitted from the light source passes through the afocal zoom telescope, and wherein, when the afocal zoom telescope is in its second position, the system is configured such that light emitted from the light source does not pass through the afocal zoom telescope; and The optical component assembly is adapted to provide imaging at least in the first field of view by passing light emitted from the light source through the afocal zoom telescope.

2. The system for performing ophthalmic optical coherence tomography as described in claim 1, wherein, The focal-free zoom telescope includes a zoom lens, wherein the position of the zoom lens is movable between a first position and a second position, wherein when the zoom lens is in its first position, the optical component group is in its first configuration, and wherein when the zoom lens is in its second position, the optical component group is in its second configuration.

3. The system for performing ophthalmic optical coherence tomography as described in claim 1, wherein, The afocal zoom telescope can be moved between its first position and its second position by rotating the afocal zoom telescope.

4. The system for performing ophthalmic optical coherence tomography as described in claim 1, wherein, The focal-free zoom telescope can be moved between its first position and its second position by translation.

5. The system for performing ophthalmic optical coherence tomography as described in claim 1, wherein, When the optical component assembly is in its first configuration, the system is configured such that light emitted from the light source propagates along a first optical path, and wherein, when the optical component assembly is in its second configuration, the system is configured such that light emitted from the light source propagates along a second optical path.

6. The system for performing ophthalmic optical coherence tomography as described in claim 5, wherein, The first optical path passes through the afocal zoom telescope, and the second optical path does not pass through the afocal zoom telescope.

7. The system for performing ophthalmic optical coherence tomography as described in claim 6, wherein, The optical component assembly further includes a first reflector at the input end of the optical component assembly, wherein the first reflector is movable between a first position and a second position, wherein when the first reflector is in its first position, the system is configured such that light emitted from the light source propagates along the first optical path, and wherein when the first reflector is in its second position, the system is configured such that light emitted from the light source propagates along the second optical path.

8. The system for performing ophthalmic optical coherence tomography as described in claim 7, wherein, The optical component group further includes a polarizing optical device at the input end of the optical component group, a polarization rotation device on the second optical path, and a polarization beam splitter at the output end of the optical component group.

9. The system for performing ophthalmic optical coherence tomography as described in claim 7, wherein, The optical component group further includes a second reflector at the output end of the optical component group.

10. The system for performing ophthalmic optical coherence tomography as described in claim 6, wherein, The optical component group further includes a beam splitter at the output end of the optical component group, wherein the beam splitter is on both the first optical path and the second optical path.

11. The system for performing ophthalmic optical coherence tomography as claimed in claim 6, wherein, The optical component assembly further includes a beam splitter, a first shutter, and a second shutter at the input end of the optical component assembly, wherein, when the optical component assembly is in its first configuration, the second shutter prevents light emitted from the light source from propagating through the second optical path, and wherein, when the optical component assembly is in its second configuration, the first shutter prevents light emitted from the light source from propagating through the first optical path.

12. The system for performing ophthalmic optical coherence tomography as described in claim 6, wherein, The optical component group further includes a polarization rotation device and a polarization beam splitter at the input end of the optical component group, and a polarization beam splitter at the output end of the optical component group.

13. The system for performing ophthalmic optical coherence tomography as claimed in claim 1, wherein, The optical component assembly further includes an input polarization beam splitter at the input end of the optical component assembly, wherein the input polarization beam splitter is adapted to separate the incident light such that light of a first polarization propagates along a first optical path passing through the afocal zoom telescope, and light of a second polarization propagates along a second optical path not passing through the afocal zoom telescope.

14. The system for performing ophthalmic optical coherence tomography as described in claim 13, wherein, The first polarization is one of TE or TM polarization, and the second polarization is the other of TE or TM polarization.

15. The system for performing ophthalmic optical coherence tomography as described in claim 13, wherein, The optical component group further includes an output polarization beam splitter at the output end of the optical component group, wherein the output polarization beam splitter is on both the first optical path and the second optical path.

16. The system for performing ophthalmic optical coherence tomography as described in claim 13, wherein, The system further includes an interferometer with a detector adapted to select each of the first polarization and the second polarization.

17. A method for performing ophthalmic optical coherence tomography, the method comprising: Emitting light from a light source; Light from the light source passes through the optical component assembly in a first field of view with a first resolution; as well as Light from the light source passes through the optical component assembly in a second field of view with a second resolution; In this context, both the first field of view and the second field of view point to the same tissue to be examined. Wherein, the first field of view is wider than the second field of view, and the second resolution is higher than the first resolution; The optical component group has a first configuration providing a first field of view with the first resolution and a second configuration providing a second field of view with the second resolution; The focal-free zoom telescope is movable between a first position and a second position. When the focal-free zoom telescope is in its first position, the optical component group is in its first configuration. And when the focal-free zoom telescope is in its second position, the optical component group is in its second configuration. Wherein, when the afocal zoom telescope is in its first position, the system is configured such that light emitted from the light source passes through the afocal zoom telescope, and wherein, when the afocal zoom telescope is in its second position, the system is configured such that light emitted from the light source does not pass through the afocal zoom telescope; and The step of causing light from the light source to pass through the optical component group in the first field of view having the first resolution includes causing light emitted from the light source to pass through the afocal zoom telescope.

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