A thromboelastograph
By designing a modular and automated thromboelastic chart, the problems of complex operation, high labor intensity and complex structure in the existing technology are solved, and efficient and automated detection is achieved, adapting to the needs of different hospitals and saving space.
Patent Information
- Application Number
- CN202111253058.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-10-27
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2041-10-27
AI Technical Summary
The existing thromboelastic charts have problems such as complex operation, high labor intensity, complex structure, small number of detection channels and large volume, which are difficult to meet the actual needs of the hospital.
A thromboelastic diagram instrument including a thromboelastic diagram detection module, an activation tube disk, a cup disk, a reagent bottle module, a sampling module, a pipetting module and a cleaning module was designed. The modular design and an automated cleaning system were adopted to simplify the combined assembly and operation process.
Efficient and automated thromboelastic map detection is realized, reducing operational complexity and labor intensity, adapting to the needs of different hospitals, saving space and improving detection efficiency.
Smart Images

Figure CN113985043B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of medical devices, and more specifically, to a thromboelastograph. Background Art
[0002] There are three types of traditional thromboelastographs: the first type is a manual instrument with almost no automation, complicated operation, and extremely high labor intensity for doctors; the second type is a semi-automatic thromboelastograph, which is currently more common on the market and is slightly simpler to operate than a manual instrument, but there are still problems such as high labor intensity and inconvenient operation when conducting large sample tests; the third type is a fully automatic thromboelastograph. Although this type of instrument currently on the market has solved the trouble of manual operation, its structure is relatively complex, the number of detection channels is relatively small, and its large size makes it inconvenient to place in the hospital's laboratory department. Summary of the invention
[0003] The technical problem to be solved by the present invention is to provide a thromboelastography instrument in view of the above-mentioned defects of the prior art.
[0004] The technical solution adopted by the present invention to solve its technical problem is:
[0005] A thromboelastograph is constructed, which includes a thromboelastograph detection module for detecting thromboelastograph items, an activation tube tray for placing activation tubes, a cup tray for placing reaction cups, a reagent bottle module, a sampling module for blood sampling, a pipetting module for pipetting and moving reaction cups, and a cleaning module; the sampling module includes a sampling needle, the pipetting module includes a pipetting needle, the cleaning module includes a sampling needle cleaning module for cleaning the sampling needle, a pipetting needle cleaning module for cleaning the pipetting needle, and a liquid circuit module, and the sampling needle cleaning module and the pipetting needle cleaning module are both connected to and controlled by the liquid circuit module.
[0006] The thromboelastograph described in the present invention further includes a frame, the thromboelastograph detection module is arranged on the rear side of the frame, the activation tube tray and the cup tray are both arranged on the front side of the frame; and the pipetting module is arranged above the cup tray.
[0007] The thromboelastograph of the present invention, wherein the frame is divided into two layers, the thromboelastograph detection module, the activation tube tray and the cup tray are installed on the upper layer of the frame, and the liquid path module is installed on the lower layer of the frame.
[0008] In the thromboelastograph of the present invention, a plurality of thromboelastograph detection modules are arranged side by side on the frame.
[0009] In the thromboelastograph described in the present invention, the sampling module further includes a sampling manipulator for driving the sampling needle to move and a first plunger pump connected to the sampling needle.
[0010] The thromboelastograph of the present invention further comprises a discard port for discarding the reaction cup.
[0011] The thromboelastograph described in the present invention, wherein the pipetting module further includes a pipetting manipulator and a clamp for clamping a reaction cup, and the clamp and the pipetting needle are both driven to move by the pipetting manipulator.
[0012] In the thromboelastograph of the present invention, the movable end of the pipetting manipulator is further provided with a second plunger pump connected to the pipetting needle.
[0013] The thromboelastograph of the present invention further comprises a transverse movement unit for driving the activation tube disc to move transversely.
[0014] In the thromboelastograph of the present invention, a refrigeration unit for cooling the reaction cup is arranged on the cup plate.
[0015] The beneficial effects of the present invention are as follows: during detection, the sampling module quantitatively collects blood from the blood test tube, and then adds the blood to the activation tube on the activation tube tray for activation. The pipetting module clamps the reaction cup from the cup tray and places it on the detection station of the thromboelastometry detection module. Then the pipetting module drives the pipetting needle to quantitatively absorb the blood in the activation tube, the reagent in the reagent cup on the cup tray, or the reagent in the reagent bottle on the reagent bottle module and add them to the reaction cup of the thromboelastometry detection module. The thromboelastometry detection module performs thromboelastometry item detection, and the sampling needle and the pipetting needle are automatically cleaned by the cleaning module after each use. The thromboelastometry instrument of the present application has good integrity, a high degree of modularization of each function, and a more concise combination assembly. Different numbers of detection modules can be matched according to actual needs to meet the needs of different hospitals, which is conducive to saving space and realizing automated detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be further described below in conjunction with the accompanying drawings and embodiments. The drawings described below are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative work:
[0017] Figure 1 This is a schematic diagram of the structure of a thromboelastograph according to a preferred embodiment of the present invention;
[0018] Figure 2 It is a top view of the thromboelastography instrument of a preferred embodiment of the present invention. DETAILED DESCRIPTION
[0019] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the following will be described clearly and completely in combination with the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are partial embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work belong to the protection scope of the present invention.
[0020] The thromboelastograph of the preferred embodiment of the present invention is as follows Figure 1 See also Figure 2 , including a thromboelastogram detection module 1 for performing thromboelastogram detection, an activation tube tray 2 for placing activation tubes, a cup tray 3 for placing reaction cups, a reagent bottle module 4, a sampling module 5 for performing blood sampling, a pipetting module 6 for performing pipetting and moving reaction cups, and a cleaning module 7; the sampling module 5 includes a sampling needle 50, the pipetting module 6 includes a pipetting needle 60, the cleaning module 7 includes a sampling needle 50 cleaning module 70 for cleaning the sampling needle, a pipetting needle cleaning module 71 for cleaning the pipetting needle 60, and a liquid circuit module 72, the sampling needle cleaning module 70 and the pipetting needle cleaning module 71 are both connected to and controlled by the liquid circuit module 72;
[0021] During the test, the sampling module 5 quantitatively collects blood from the blood test tube, and then adds the blood to the activation tube on the activation tube tray 2 for activation. The pipetting module 6 clamps the reaction cup from the cup tray 3 and places it on the detection station of the thromboelastogram detection module 1. Then the pipetting module 6 drives the pipetting needle 60 to quantitatively absorb the blood in the activation tube, the reagent in the reaction cup on the cup tray 3, or the reagent in the reagent bottle module 4 to the reaction cup of the thromboelastogram detection module 1 (corresponding cleaning is required after each absorption). The thromboelastogram detection module 1 performs thromboelastogram item detection. The sampling needle 50 and the pipetting needle 60 are automatically cleaned by the cleaning module 7 after each use.
[0022] The thromboelastograph of the present application has good integrity, high modularity of functions, and simpler assembly. Different numbers of detection channels can be matched according to actual needs to meet the needs of different hospitals, which is conducive to saving space and realizing automated detection.
[0023] It should be noted that the thromboelastography instrument of the present application does not include a (blood test tube) sampling device, and when used, one can choose to use a sampling station or manual sampling.
[0024] Preferably, the reagent bottle module 4 is arranged between the activation tube tray 2 and the cup tray 3;
[0025] Preferably, the thromboelastograph also includes a frame 8, the thromboelastograph detection module 1 is arranged on the rear side of the frame 8, the activation tube tray 2 and the cup tray 3 are both arranged on the front side of the frame 8; the pipetting module 6 is arranged above the cup tray 3; the layout is reasonable and compact, which is convenient for human intervention and status monitoring.
[0026] Preferably, the rack 8 is divided into two layers, the upper layer of the rack 8 is installed with the thromboelastogram detection module 1, the activation tube tray 2 and the cup tray 3, and the lower layer of the rack 8 is installed with the liquid path module 72; the layout is reasonable and the integrity is good.
[0027] Preferably, a plurality of thromboelastogram detection modules 1 are arranged side by side on the rack 8, so as to facilitate multi-station thrombus detection.
[0028] Preferably, the sampling module 5 further includes a sampling manipulator 51 for driving the sampling needle 50 to move and a first plunger pump 52 connected to the sampling needle 50; the sampling manipulator 51 and the first plunger pump are easy to control, and existing equipment can be used.
[0029] Preferably, the thromboelastograph also includes a discarded reaction cup discarding port 9, which is convenient for discarding the reaction cup on the thromboelastograph detection module 1 after the detection is completed; preferably, the reaction cup discarding port 9 is set between the activation tube plate 2 and the cup plate 3.
[0030] Preferably, the pipetting module 6 also includes a pipetting manipulator 61 and a clamp 62 for clamping a reaction cup, and the clamp 62 and the pipetting needle 60 are both moved by the pipetting manipulator 61; the pipetting manipulator 61 and the clamp 62 can be used to sample existing equipment; during installation, a lifting cylinder or the like can be set on the manipulator to drive one or both of the clamp 62 and the pipetting needle 60 to avoid interference, or the lateral spacing between the clamp 62 and the pipetting needle 60 can be controlled to avoid interference.
[0031] Preferably, the movable end of the pipetting manipulator 61 is further provided with a second plunger pump 63 connected to the pipetting needle 60 .
[0032] Preferably, the thromboelastogram instrument further includes a transverse movement unit 10 for driving the activated tube disk 2 to move transversely, so as to facilitate sampling with a sampling manipulator and improve sampling efficiency.
[0033] Preferably, a refrigeration unit for cooling the reaction cup is provided on the cup plate 3, so as to facilitate the storage of the reagent for a longer period of time.
[0034] It should be understood that those skilled in the art can make improvements or changes based on the above description, and all these improvements and changes should fall within the scope of protection of the appended claims of the present invention.
Claims
1. A thromboelastograph, characterized in that: The invention comprises a thromboelastogram detection module for detecting thromboelastogram items, an activation tube tray for placing activation tubes, a cup tray for placing reaction cups, a reagent bottle module, a sampling module for sampling blood, a pipetting module for pipetting and moving reaction cups, and a cleaning module; the sampling module comprises a sampling needle, the pipetting module comprises a pipetting needle, the cleaning module comprises a sampling needle cleaning module for cleaning the sampling needle, a pipetting needle cleaning module for cleaning the pipetting needle, and a liquid circuit module, the sampling needle cleaning module and the pipetting needle cleaning module are both connected to and controlled by the liquid circuit module; during detection, the sampling module After quantitatively collecting blood from the blood test tube, the blood is added to the activation tube on the activation tube tray for activation. The pipetting module clamps the reaction cup from the cup tray and places it on the detection station of the thromboelastometry detection module. Then the pipetting module drives the pipetting needle to quantitatively absorb the blood in the activation tube to the reaction cup of the thromboelastometry detection module. The pipetting module drives the pipetting needle to quantitatively absorb the reagent in the reaction cup on the cup tray or the reagent in the reagent bottle module to the reaction cup of the thromboelastometry detection module. The thromboelastometry detection module performs thromboelastometry item detection. The sampling needle and the pipetting needle are automatically cleaned by the cleaning module after each use. The thromboelastograph also includes a frame, the thromboelastograph detection module is arranged at the rear side of the frame, and the activation tube tray and the cup tray are both arranged at the front side of the frame; The liquid transfer module is arranged above the cup plate; The frame is divided into two layers, the upper layer of the frame is equipped with the thromboelastogram detection module, the activation tube tray and the cup tray, and the lower layer of the frame is equipped with the liquid path module; a plurality of thromboelastogram detection modules are arranged side by side on the frame.
2. The thromboelastograph according to claim 1, characterized in that: The sampling module also includes a sampling manipulator for driving the sampling needle to move and a first plunger pump connected to the sampling needle.
3. The thromboelastograph according to claim 1, characterized in that: The thromboelastograph also includes a discard port for discarding the reaction cup.
4. The thromboelastograph according to claim 1, characterized in that: The pipetting module also includes a pipetting manipulator and a clamping claw for clamping a reaction cup, and both the clamping claw and the pipetting needle are driven to move by the pipetting manipulator.
5. The thromboelastograph according to claim 4, characterized in that: The movable end of the pipetting manipulator is also provided with a second plunger pump connected to the pipetting needle.
6. The thromboelastograph according to claim 1, characterized in that: The thromboelastogram instrument further comprises a transverse movement unit for driving the activation tube disc to move transversely.
7. The thromboelastograph according to claim 1, characterized in that: The cup plate is provided with a refrigeration unit for cooling the reaction cup.
Citation Information
Patent Citations
Integrated module structure and equipment for thrombus elasticity and blood coagulation analysis
CN113219188A
Full-automatic chemiluminescence immunoassay analyzer
CN113504380A