Global ablation simulation method, apparatus, storage medium, and device for ablation needle

By simulating the temperature field and parameters of the target ablation region, the maximum set of ablation needle parameters is determined, which solves the problem of local optimization in the existing technology, achieves the global optimal ablation effect, and improves the ablation efficiency and accuracy of the ablation needles.

CN113987739BActive Publication Date: 2026-01-30CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI +1
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Patent Information

Application Number
CN202111064076.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-09-10
Publication Date
2026-01-30
Estimated Expiration
2041-09-10

AI Technical Summary

Technical Problem

Existing ablation techniques often fail to achieve the most optimal ablation scheme, leading to local optima and failing to maximize the ablation effect.

Method used

By simulating the target ablation area and performing temperature field simulation, the maximum set of ablation needle parameters for the combination of ablation needles is determined. Then, the parameters of each ablation needle are iterated to determine a specific set of ablation needle parameters, thereby achieving global ablation.

Benefits of technology

It provides the most accurate and optimal simulated needle application scheme, avoids local optima, achieves complete ablation of the target ablation area, and improves ablation efficiency and accuracy.

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Patent Text Reader

Abstract

This invention discloses a global ablation simulation method, apparatus, storage medium, and device for ablation needles. The method includes: simulating a target ablation region based on the target ablation tissue; performing temperature field simulation based on the target ablation region to obtain temperature distribution values; performing parameter simulation on an ablation needle assembly based on the temperature distribution values ​​to determine a maximum needle application parameter set; the ablation needle assembly includes one or more ablation needles; performing parameter traversal on each ablation needle based on the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle; by applying the method provided in this application embodiment, a reasonable ablation scheme can be obtained to achieve complete ablation of the target ablation region.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of data processing, and in particular to a global ablation simulation method and device for ablation needles, a storage medium and equipment. BACKGROUND

[0002] Ablation techniques are generally divided into two categories: thermal ablation and cold ablation. The principle of both is to insert an ablation needle into target tissue, use the ablation needle to generate local physical high or low temperature to disintegrate the cell tissue structure, and cause direct necrosis of the tissue cells, thereby achieving the purpose of local ablation.

[0003] In the process of ablation or simulation of ablation of an ablation object, the conventional ablation idea is to first ablate the ablation object by using one ablation needle, determine the remaining ablation region after ablation, and then continue to insert the needle. This approach is prone to local optimization, and thus cannot obtain the most reasonable ablation scheme, i.e., cannot maximize the ablation effect. When the ablation effect of the first ablation needle has been achieved, it is difficult to adjust to achieve complete ablation. SUMMARY

[0004] To solve the problem of the prior art that a reasonable ablation scheme cannot be obtained, the present application provides a global ablation simulation method and device for ablation needles, a storage medium and equipment.

[0005] According to a first aspect of the present application, a global ablation simulation method for ablation needles is provided, which includes: simulating a target ablation region according to a target ablation tissue; performing temperature field simulation according to the target ablation region to obtain a temperature distribution value; performing parameter simulation on an ablation needle combination according to the temperature distribution value to determine a maximum needle insertion parameter set; the ablation needle combination includes one or more ablation needles; performing parameter iteration on each ablation needle according to the maximum needle insertion parameter set to determine a specific needle insertion parameter set corresponding to each ablation needle.

[0006] According to an embodiment of the present application, after determining the specific needle insertion parameter set corresponding to each ablation needle, the method further includes: outputting a corresponding simulation needle insertion scheme according to the specific needle insertion parameter set corresponding to each ablation needle.

[0007] According to an embodiment of the present application, the parameter simulation on the ablation needle combination according to the temperature distribution value to determine the maximum needle insertion parameter set includes: determining a maximum ablation region according to the target ablation region and a target reserved region; performing parameter simulation on each needle insertion parameter according to the maximum ablation region to determine the maximum needle insertion parameter set corresponding to each ablation needle.

[0008] According to an embodiment of the present application, the determining the maximum ablation region according to the target ablation region and the target reserved region comprises: determining a target reserved tissue, simulating the target reserved tissue according to the target ablation region to obtain a target reserved region; and performing ablation region simulation according to the target reserved region and the target ablation region to determine the maximum ablation region.

[0009] According to an embodiment of the present application, the performing ablation region simulation according to the target reserved region and the target ablation region to determine the maximum ablation region comprises: determining a simulation region; screening the simulation region according to the target ablation region to obtain a region coverage value; screening the simulation region according to the target reserved region to obtain a region penalty value; integrating the region coverage value and the region penalty value to obtain a region evaluation value; and determining the simulation region corresponding to the region evaluation value with the largest value as the maximum ablation region.

[0010] According to an embodiment of the present application, the performing parameter traversal on each ablation needle according to the maximum needle insertion parameter set to determine a specific needle insertion parameter set corresponding to each ablation needle comprises: performing parameter traversal on a single ablation needle according to the maximum needle insertion parameter set to determine a simulation data set corresponding to the single ablation needle; wherein the simulation data set comprises a simulation needle insertion parameter set and a corresponding simulation region; determining an ablation needle number corresponding to the ablation needle combination, combining the simulation needle insertion parameter set and the corresponding simulation region according to the ablation needle number to determine a simulation combination set; wherein the simulation combination set comprises a combination needle insertion parameter set and a combination ablation region; screening the combination ablation region according to the target ablation region to obtain a combination needle insertion parameter set satisfying a screening condition; and determining a specific needle insertion parameter set corresponding to each ablation needle according to the combination needle insertion parameter set.

[0011] According to an embodiment of the present application, the method further comprises: determining a specific ablation region corresponding to the ablation needle according to the specific needle insertion parameter set corresponding to the ablation needle; and determining an ablation center corresponding to the ablation needle according to the specific ablation region.

[0012] According to an embodiment of the present application, the needle insertion parameter set comprises an ablation needle power, an ablation needle size, an ablation time and an ablation needle angle.

[0013] According to the second aspect of the present application, there is further provided a global ablation simulation device for an ablation needle, the device comprising: a region simulation module configured to simulate a target ablation region according to target ablation tissue; a temperature field simulation module configured to simulate a temperature field according to the target ablation region to obtain a temperature distribution value; a parameter simulation module configured to simulate parameters of an ablation needle combination according to the temperature distribution value to determine a maximum needle application parameter set, the ablation needle combination comprising one or more ablation needles; and a traversal module configured to traverse parameters of each ablation needle according to the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle.

[0014] According to an embodiment of the present application, the device further comprises an output module configured to output a corresponding simulation needle application scheme according to the specific needle application parameter set corresponding to each ablation needle.

[0015] According to an embodiment of the present application, the parameter simulation module comprises a first determination sub-module configured to determine a maximum ablation region according to the target ablation region and a target reserved region; and a simulation sub-module configured to simulate parameters of each needle application according to the maximum ablation region to determine a maximum needle application parameter set corresponding to each ablation needle.

[0016] According to an embodiment of the present application, the determination sub-module comprises a determination of target reserved tissue, a simulation of the target reserved tissue according to the target ablation region to obtain a target reserved region, and an ablation region simulation according to the target reserved region and the target ablation region to determine a maximum ablation region.

[0017] According to an embodiment of the present application, the traversal module comprises a traversal sub-module configured to traverse parameters of a single ablation needle according to the maximum needle application parameter set to determine a simulation data set corresponding to the single ablation needle, wherein the simulation data set comprises a simulation needle application parameter set and a corresponding simulation region; a combination sub-module configured to determine a number of ablation needles corresponding to the ablation needle combination, combine the simulation needle application parameter set and the corresponding simulation region according to the number of ablation needles to determine a simulation combination set, wherein the simulation combination set comprises a combined needle application parameter set and a combined ablation region; a second screening sub-module configured to screen the combined ablation region according to the target ablation region to obtain a combined needle application parameter set satisfying a screening condition; and a third determination sub-module configured to determine a specific needle application parameter set corresponding to each ablation needle according to the combined needle application parameter set.

[0018] According to an embodiment of the present application, the device further comprises a determination module configured to determine a specific ablation region corresponding to the ablation needle according to the specific needle application parameter set corresponding to the ablation needle; and the determination module is further configured to determine an ablation center corresponding to the ablation needle according to the specific ablation region.

[0019] According to a third aspect of the present application, there is further provided a computer device comprising a memory, a processor, and a computer program stored on the memory and executable on the processor, the processor implementing the method for global ablation simulation of ablation needles as described in any of the above aspects when executing the program.

[0020] According to a fourth aspect of the present application, there is further provided a storage medium containing computer executable instructions for performing the method for global ablation simulation of ablation needles as described in any of the above aspects when executed by a computer processor.

[0021] The method for global ablation simulation of ablation needles provided by the embodiments of the present application simulates a target ablation region corresponding to a target ablation tissue, performs temperature field simulation on the target ablation region, and obtains corresponding temperature distribution values; determines a maximum needle insertion parameter set by performing parameter simulation on the ablation needle combination according to the temperature distribution values, and iterates the maximum needle insertion parameter set to determine a specific needle insertion parameter set corresponding to each ablation needle, so that the ablation needle combination corresponding to the specific needle insertion parameter set can achieve complete ablation of the target ablation region. By applying the method, the overall ablation scheme of the corresponding ablation needle combination can be determined by the method of global ablation simulation of the ablation needle combination, and the global consideration of ablation of the entire target ablation region is based on, which avoids the situation of local optimization, so that the optimal specific needle insertion parameter set of each ablation needle in the corresponding ablation needle combination can be provided to obtain a global optimal selection, thereby providing the most accurate and optimal simulated needle insertion scheme.

[0022] It should be understood that the teachings of the present application do not require all the beneficial effects described above to be achieved, but specific technical solutions can achieve specific technical effects, and other embodiments of the present application can also achieve beneficial effects not mentioned above. BRIEF DESCRIPTION OF DRAWINGS

[0023] The above and other objects, features and advantages of the exemplary embodiments of the present application will be more apparent from the following detailed description taken in conjunction with the accompanying drawings, in which:

[0024] In the drawings, identical or corresponding reference signs refer to identical or corresponding parts.

[0025] Figure 1 An implementation flowchart of the method for global ablation simulation of ablation needles according to an embodiment of the present application is shown Figure 1 ;

[0026] Figure 2 An implementation flowchart of the method for global ablation simulation of ablation needles according to an embodiment of the present application is shown Figure 2 ;

[0027] Figure 3 This illustration shows an implementation scenario of a global ablation simulation method for an ablation needle according to an embodiment of the present invention. Figure 1 ;

[0028] Figure 4 This diagram illustrates a schematic of the implementation module of a global ablation simulation device for an ablation needle according to an embodiment of the present invention.

[0029] Figure 5 A schematic diagram of the implementation structure of a computer device according to an embodiment of the present invention is shown. Detailed Implementation

[0030] The principles and spirit of the invention will now be described with reference to several exemplary embodiments. It should be understood that these embodiments are provided merely to enable those skilled in the art to better understand and implement the invention, and are not intended to limit the scope of the invention in any way. Rather, these embodiments are provided to make the invention more thorough and complete, and to fully convey the scope of the invention to those skilled in the art.

[0031] The technical solution of the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0032] Figure 1 This illustration shows the implementation flow of a global ablation simulation method for an ablation needle according to an embodiment of the present invention. Figure 1 .

[0033] See Figure 1 According to a first aspect of the present invention, a global ablation simulation method for ablation needles is provided, the method comprising: operation 101, simulating a target ablation region based on a target ablation tissue; operation 102, performing temperature field simulation based on the target ablation region to obtain temperature distribution values; operation 103, performing parameter simulation on an ablation needle assembly based on the temperature distribution values ​​to determine a maximum needle application parameter set; the ablation needle assembly includes one or more ablation needles; operation 104, performing parameter traversal on each ablation needle based on the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle.

[0034] The embodiment of the present application provides a global ablation simulation method for an ablation needle, the method comprises the following steps: simulating a target ablation region corresponding to target ablation tissue, performing temperature field simulation on the target ablation region, and obtaining corresponding temperature distribution values; performing parameter simulation on an ablation needle combination according to the temperature distribution values to determine a maximum needle application parameter set, and performing iteration on the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle, and the ablation needle combination corresponding to the specific needle application parameter set can realize complete ablation of the target ablation region. The method is suitable for a medical device with an ablation function, and can also be suitable for a control device or an auxiliary device for controlling the medical device. Further, the ablation referred to in the embodiment of the method can be one of cold ablation or hot ablation. By using the method, the overall ablation scheme of the corresponding ablation needle combination can be determined by performing global ablation simulation on the ablation needle combination, the global consideration of ablation of the entire target ablation region is considered, the case of local optimization is avoided, and therefore the optimal specific needle application parameter set of each ablation needle in the corresponding ablation needle combination can be provided, the global optimal selection is obtained, and the most accurate and optimal simulated needle application scheme is provided.

[0035] In operation 101 of the method, the target ablation tissue is tissue that needs to be ablated by an organism, such as tumor tissue in a human body. The method can simulate the target ablation tissue according to at least one of the shape and size of the target ablation tissue to obtain a target ablation region. Specifically, the method can construct the shape and size of the target ablation tissue in a Cartesian coordinate system by using an electronic device to obtain the target ablation region.

[0036] It should be noted that the method can perform three-dimensional image acquisition on the target ablation tissue by using an image acquisition device to obtain a three-dimensional image of the target ablation tissue, and the three-dimensional image is constructed to obtain the target ablation region. In a specific embodiment, when the target ablation tissue is tumor tissue, a CT machine can be used to perform image acquisition on the tumor tissue, and a three-dimensional image corresponding to the tumor tissue can be obtained by CT slicing and three-dimensional reconstruction processing on the obtained CT image.

[0037] In operation 102 of the method, by simulating the temperature field of the target ablation region, the temperature variation law of the target ablation region and the temperature distribution value corresponding to the target ablation region can be understood. Specifically, the method can simulate the temperature field based on the heat transfer process of the ablation needle in the target ablation tissue over time to understand the corresponding temperature distribution value under the ablation condition of the target ablation region. Further, according to the actual situation, when the ablation process of the present application is transferred in the heat conduction mode, the temperature distribution value can be simulated by the heat conduction equation, and the numerical solution method can be generally used. When the ablation process of the present application is transferred in the convection heat transfer mode, if the velocity distribution is known, the temperature distribution can be simulated by the energy equation. That is, according to the specific implementation scenario of the target ablation region, the corresponding temperature field simulation equation can be selected to simulate the temperature distribution value.

[0038] In operation 103 of the method, in the case of known temperature distribution value and target ablation region, the ablation needle can be simulated to obtain the needle parameter corresponding to the ablation needle. In order to ensure that each ablation needle and each combination of the corresponding ablation needle can be evaluated, the maximum needle parameter is determined to determine the value range of each needle parameter of the single ablation needle. Specifically, the method can calculate based on the temperature distribution value combined with the relationship between the needle parameter and the corresponding ablation region to determine the maximum needle parameter set.

[0039] The needle parameter set of the method specifically includes the following parameters: ablation needle power, ablation needle size, ablation time, and ablation needle angle.

[0040] In one implementation, the ablation needle parameters in the needle parameter set include ablation needle power, ablation needle size, ablation time, and ablation needle angle, a total of five needle parameters. Correspondingly, by simulating each parameter by the target ablation region, the maximum needle parameter set can include the maximum ablation needle power corresponding to the target ablation region, the maximum ablation needle size corresponding to the target ablation region, the maximum ablation time corresponding to the target ablation region, and the maximum ablation needle angle corresponding to the target ablation region.

[0041] It should be noted that the method can further determine the ablation needle energy according to the abovementioned needle application parameters. Specifically, in the case where the ablation needle size is known, the ablation needle energy is determined by the ablation needle power and the ablation needle size. In another implementation, since the ablation needle power and the ablation needle size have a certain correlation, the ablation needle application parameters in the ablation needle application parameter set can include any one of the ablation needle power and the ablation needle size, in addition to the ablation time and the ablation needle angle. There are three kinds of needle application parameters. Correspondingly, the maximum needle application parameter set can include the maximum ablation needle power corresponding to the target ablation region and the maximum ablation needle size corresponding to the target ablation region, the maximum ablation time corresponding to the target ablation region and the maximum ablation needle angle corresponding to the target ablation region. The ablation needle size can specifically refer to the thickness of the ablation needle or the ablation needle model. By determining the maximum needle application parameter set corresponding to each ablation needle, the upper and lower bounds of the value of each ablation needle application parameter can be determined.

[0042] In one implementation, according to the target ablation region, the maximum ablation angle can be less than 180°, in which case the maximum ablation angle is determined according to the target ablation region. In another implementation, according to the target ablation region, the maximum ablation angle is not limited, in which case 180° is taken as the maximum ablation angle. It should be understood that the maximum needle application parameter set is applicable to each ablation needle in the ablation needle combination.

[0043] In operation 104 of the method, the traversal range of each ablation parameter of each ablation needle can be determined according to the maximum needle application parameter set. By traversing each ablation parameter of each ablation needle, a plurality of needle application parameters corresponding to each ablation needle can be determined. By combining each needle application parameter and performing ablation simulation, a specific needle application parameter set corresponding to each ablation needle can be determined from the plurality of needle application parameters. The specific needle application parameter set is the optimal needle application parameter of each ablation needle in the ablation needle combination when the target ablation region needs to be ablated by the ablation needle combination. The medical device performs needle application ablation according to the optimal needle application parameter, which can achieve the purpose of completely ablating the target ablation region under the optimal solution.

[0044] According to an embodiment of the present application, after the specific needle application parameter set corresponding to each ablation needle is determined in operation 104, the method further includes outputting a corresponding simulation needle application scheme according to the specific needle application parameter set corresponding to each ablation needle. It should be understood that when each ablation needle in the ablation needle combination corresponds to a respective specific needle application parameter set, the simulation needle application scheme corresponding to each ablation needle by the specific needle application parameter set is the optimal simulation needle application scheme in the ablation needle combination. Under the optimal simulation needle application scheme, the ablation needle combination can be instructed, controlled or assisted to completely ablate the target ablation region.

[0045] According to an embodiment of the present application, operation 103, parameter simulation of the ablation needle combination according to the temperature distribution value, determines the maximum needle insertion parameter set, including: first, determining the maximum ablation region according to the target ablation region and the target preservation region; then, parameter simulation of each needle insertion parameter according to the maximum ablation region, determines the maximum needle insertion parameter set corresponding to each ablation needle.

[0046] Through the above operation, each ablation needle will correspond to a specific needle insertion parameter set, and the needle insertion parameter set represents the specific value of those parameters corresponding to a needle. Whether it is a global optimization method or other parameter exploration method, it is to determine the needle insertion parameter set corresponding to each needle and output.

[0047] Before performing operation 103, the present method needs to determine the temperature distribution value first, and the determination method of the temperature distribution value specifically includes: first, heat conduction simulation of the target ablation region according to the biological heat conduction equation, to determine the region simulation heat capacity, the region simulation thermal conductivity and the ablation heat value; then, determining the temperature distribution value according to the region simulation heat capacity, the region simulation thermal conductivity and the ablation heat value.

[0048] The present method simulates the biological heat transfer process based on the ablation needle changing with time based on the biological heat conduction equation. Thus, the temperature field numerical simulation of the heat transfer between the ablation needle and the biological tissue at different times is obtained.

[0049] Specifically, the present method uses the biological heat conduction equation based on Pennes to simulate the temperature field, and the specific formula of the biological heat conduction equation is as follows:

[0050]

[0051] Wherein, C is used to represent the tissue heat capacity corresponding to the target ablation tissue; T is used to represent the tissue temperature corresponding to the target ablation tissue; t is used to represent the time corresponding to the ablation needle; k is used to represent the thermal conductivity coefficient corresponding to the target ablation tissue; X is used to represent each point on the target ablation tissue, which can be represented by the coordinates (x, y, z) by constructing the target ablation tissue in the Cartesian coordinate system; T(X, t) can be used to represent the temperature of each point at each time.

[0052] C b is used to represent the blood heat capacity corresponding to the target ablation tissue; ω b is used to represent the blood perfusion corresponding to the target ablation tissue; Q m is used to represent the effective metabolic heat generation corresponding to the target ablation tissue, T a is used to represent the arterial temperature corresponding to the target ablation tissue.

[0053] Wherein, the blood-related parameters C b , ωb , T a and the metabolic-related parameter Q m It is difficult to obtain in real time, so in the simulation of the method, the bio-heat conduction equation is optimized, specifically, the optimization method can be omitted or replaced by a constant, and then the optimized heat conduction equation is:

[0054]

[0055] wherein, can represent the heat required for ablation corresponding to each point of the target ablation region; can represent the self-heat corresponding to each point of the target ablation region, Q r can represent the heat required to be provided by the ablation needle corresponding to each point of the target ablation region.

[0056] When the tissue heat capacity C, the thermal conductivity k and the ablation needle heat Q r are known, the temperature distribution value of the target ablation region, i.e. the distribution of the temperature value corresponding to each coordinate point of the target ablation region, can be analyzed and obtained through the heat conduction equation. After determining the temperature distribution value, the method can simulate a single simulation region corresponding to a single ablation needle according to the temperature distribution value.

[0057] The principle is as follows. Since the temperature field shape corresponding to each ablation of the ablation needle is known, specifically, the temperature field shape corresponding to the ablation needle is an ellipsoid, the standard volume formula of the ellipsoid in the Cartesian coordinate system can be obtained:

[0058]

[0059] wherein, (x, y, z) is used to represent the coordinate point of any point on the boundary of the ellipsoid when the geometric center of the ellipsoid is at the origin, and a, b, c are used to represent the radius of the ellipsoid.

[0060] It is known that the simulation region corresponding to the ablation needle is the set of all points inside the ellipsoid, and the vertex of the ablation needle is the geometric center of the ellipsoid, so the set of all points of the simulation region can be represented as:

[0061]

[0062] As above, wherein (x, y, z) is used to represent all coordinate points of the simulation region when the geometric center of the simulation region is at the origin, and abc is used to represent the radius of the simulation region.

[0063] The needle insertion parameters of the ablation needle and the ablation needle heat Q r can be associated. Specifically, the ablation needle heat Q r is associated with the ablation needle power W, the ablation needle size d and the ablation time t.

[0064] by needle parameter mapping to extended in the middle, that is, by ablation needle power W, ablation needle size d, ablation time t, the re-mapping.

[0065] Further consider that when the target ablation area is simulated in the Cartesian coordinate system, the ablation needle also needs to be simulated in the Cartesian coordinate system, and the ablation needle angle can also affect the shape of the simulated area. The ablation needle angle, as one of the needle parameters, can be characterized by the deflection angle θ1 of the ablation needle from the positive direction of the x-axis and the deflection angle θ2 of the ablation needle from the positive direction of the z-axis.

[0066] Combined with the constraints of ablation needle heat Qr on ablation needle power W, ablation needle size d, and ablation time t, the corresponding fifth-order polynomials f1, f2, and f3 can be constructed to re-map .

[0067] The specific fifth-order polynomials are as follows:

[0068] x 2 ×f1(W, d, t, θ1) + y 2 ×f2(W, d, t, θ1) + z 2 ×f3(W, d, t, θ2) ≤ 1

[0069] According to the actual situation, the above fifth-order polynomials f1, f2, and f3 are fitted, such as the coordinate point set of the actual ablation area under different parameter settings of the ablation needle according to the actual situation, to fit the fifth-order polynomials f1, f2, and f3, thereby obtaining the corresponding parameters of the polynomials to determine the target mapping function. Specifically, the simulated area of the ablation needle in the static state can be characterized as:

[0070] S = f4(W, d, t, θ1, θ2)

[0071] Wherein, S is used to represent the simulated area corresponding to the ablation needle.

[0072] Based on the above formula, by traversing the ablation needle power W, the ablation needle size d, the ablation time t, the deflection angle θ1 and the deflection angle θ2 of the ablation needle reaching the ablation temperature under different ablation needle power W, ablation needle size d, and ablation time t, a plurality of sets of simulated parameters and corresponding simulated areas corresponding to the ablation needle can be obtained.

[0073] Similarly, after the temperature distribution value is determined, the method can determine a maximum ablation region according to the target ablation region and the target reserved region, where the maximum ablation region refers to an optimal ablation region of the ablation needle combination in the simulation, and generally, the optimal ablation region needs to satisfy complete coverage of the target ablation region and minimize damage to the target reserved region.

[0074] In one implementation, when the combined ablation region corresponding to the ablation needle combination is completely non-intersected with the target reserved region, the maximum ablation region can be determined according to the target ablation region. Specifically, as long as the maximum ablation region can completely cover the volume of the target ablation region, the size of the maximum ablation region is not less than the size of the target ablation region, and the boundary of the maximum ablation region exceeds or overlaps the boundary of the target ablation region.

[0075] After the maximum ablation region is determined, according to the function of the simulation region and the needle placement parameter, the method can determine a maximum needle placement parameter set according to the maximum ablation region.

[0076] Specifically, the association formula of the maximum needle placement parameter set and the maximum ablation region can be represented as:

[0077] S1=f4(W max ,d max ,t max )=argmax(S1)

[0078] Where S1 is used to represent the simulation region, argmax(S1) is used to represent the maximum ablation region, W max , d max , t max is used to represent the needle placement parameter related to the maximum ablation region. Where W max is used to represent the maximum power of the ablation needle, d max is used to represent the maximum size of the ablation needle, and t max is used to represent the maximum time of the ablation needle. Further, in order to optimize the calculation and ensure the comprehensiveness of the needle placement parameter, when the maximum needle placement parameter set is determined, the ablation needle combination can be preset as a single ablation needle, so that the maximum needle placement parameter in the maximum needle placement parameter set can be used for parameter traversal of each ablation needle.

[0079] According to an embodiment of the present application, determining the maximum ablation region according to the target ablation region and the target reserved region comprises: first, determining the target reserved tissue, simulating the target reserved tissue according to the target ablation region to obtain the target reserved region; and then, simulating the ablation region according to the target reserved region and the target ablation region to determine the maximum ablation region.

[0080] In another implementation scenario, when the combined ablation region corresponding to the ablation needle combination intersects with the target reserved region, the target ablation region needs to be considered at the same time to ensure that the maximum ablation region covers the target ablation region as much as possible while reducing the coverage of the target reserved region as much as possible. In the case of considering the target reserved region, the simulation region corresponding to the ablation needle combination can be controlled to eliminate the target ablation region as much as possible without damaging the target reserved region, which can avoid the obtained simulation needle placement scheme causing damage to the target reserved tissue corresponding to the target reserved region, improve the safety of the obtained simulation needle placement scheme, and make the method more suitable for the needle placement simulation scene of actual tissue.

[0081] The target reserved tissue is also the tissue inside the organism, which can usually be selected from the tissue around the target ablation tissue. For example, when the target ablation tissue is tumor tissue, the target reserved tissue can be the organs and muscles within a certain range around the tumor tissue. After determining the target reserved tissue, the method needs to simulate the target reserved tissue according to the target ablation region. Specifically, when the method establishes the target ablation region corresponding to the target ablation tissue in the coordinate system through the electronic device, the method can establish the target reserved region corresponding to the target reserved tissue according to the position of the target ablation region in the same coordinate system, so that the coordinate system can reflect the relative positions of the target ablation region and the target reserved region.

[0082] Similarly, by determining the relative positions between the simulation region and the target ablation region and the target reserved region, the intersection between the simulation region and the target ablation region and the intersection between the simulation region and the target reserved region can be determined. According to the specific circumstances of the two intersections, the simulation region can be evaluated to determine the maximum ablation region. The maximum ablation region can be understood as the optimal ablation region corresponding to the ablation needle combination.

[0083] In this implementation scenario, the association formula between the maximum needle placement parameter set and the maximum ablation region can be characterized as:

[0084] S1=f4(W max , d max , t max )=argmax(S1-(S H ∩S1)

[0085] Wherein, S1 is used to represent the simulation region, argmax(S1-(S H ∩S1) is used to represent the maximum ablation region, S H is used to represent the target reserved region, W max , d max , t max is used to represent the needle placement parameters related to the maximum ablation region. Wherein, Wmax for characterizing the ablation needle maximum power, d max for characterizing the ablation needle maximum size, t max for characterizing the ablation needle maximum time.

[0086] Further, the method can determine the tolerance value corresponding to the target reserved area by performing tolerance simulation on the target reserved area, determine the penalty weight corresponding to the target reserved area according to the tolerance value, and weight the target reserved area by the penalty weight, so that the target reserved area is more suitable for the actual scene. The value range of the weight value can be (0, +∞]. Specifically, if the tolerance value of the target reserved area is high, the value of the penalty weight can be set to a large value, such as any positive number greater than 1. If the tolerance value of the target reserved area is low, the value of the penalty weight can be set to a small value, such as any positive number less than 1.

[0087] In this implementation scenario, the association formula of the maximum needle insertion parameter set and the maximum ablation region can be characterized as:

[0088] S1=f4(W max , d max , t max )=argmax(S1-λ×(S H ∩S1))

[0089] Wherein, λ is used to characterize the penalty weight.

[0090] It should be noted that when the verification is , it can be understood that the target reserved area will not affect the maximum ablation region.

[0091] In the above implementation scenario, the maximum range of the default deflection angle is 180°. In this way, the maximum deflection angle of the deflection angle θ1 and the deflection angle θ2 can not be determined in the association formula of the maximum needle insertion parameter set and the maximum ablation region.

[0092] Specifically, the maximum needle insertion parameter set corresponding to the maximum deflection angle of the ablation needle obtained by the above formula in cooperation with the preset maximum deflection angle of the ablation needle can be characterized as:

[0093] ablation needle maximum power W max , ablation needle maximum size d max , ablation needle maximum time t max , ablation needle maximum deflection angle θ 1max 180°, ablation needle maximum deflection angle θ 2max 180°.

[0094] Figure 2 Fig. 1 shows an implementation process of a global ablation simulation method for an ablation needle according to an embodiment of the present application Figure 2 .

[0095] Referring to Figure 2 According to an embodiment of the present application, operation 104, determining the specific needle insertion parameter set corresponding to each ablation needle according to the maximum needle insertion parameter set, comprises: operation 1041, performing parameter traversal on a single ablation needle according to the maximum needle insertion parameter set to determine a simulation data set corresponding to the single ablation needle; wherein the simulation data set comprises a simulation needle insertion parameter set and a corresponding simulation region; operation 1042, determining the number of ablation needles corresponding to the combination of ablation needles, combining the simulation needle insertion parameter set and the corresponding simulation region according to the number of ablation needles to determine a simulation combination set; wherein the simulation combination set comprises a combined needle insertion parameter set and a combined ablation region; operation 1043, screening the combined ablation region according to the target ablation region to obtain a combined needle insertion parameter set that meets the screening condition; operation 1044, determining the specific needle insertion parameter set corresponding to each ablation needle according to the combined needle insertion parameter set.

[0096] The present method can provide suggestions for needle insertion parameters based on simulation of the temperature field of the ablation needle by traversing the needle insertion parameter set of each ablation needle, thereby accurately and comprehensively freezing and ablating target ablation tissues of different shapes and improving the stability and accuracy of ablation operation.

[0097] The present application can determine the ablation regions formed by multiple ablation needles under all possible parameter combinations through simulation, thereby comparing to obtain the best ablation needle setting combination to as perfectly as possible simulate the target ablation region, and also allowing the subsequent multiple ablation needles to reach the corresponding ablation center at one time according to the simulation needle insertion result and ablate according to the specific ablation parameter set, further reducing the efficiency of each ablation needle placement and ablation and improving the ablation efficiency.

[0098] After obtaining the maximum needle insertion parameter set, the present method can determine the parameter range that needs to be traversed according to the maximum needle insertion parameter set. Specifically, the parameter range corresponding to each ablation needle i can be set as:

[0099] W i ∈[0,W max ],

[0100] d i ∈[0,d max ],

[0101] t i ∈[0,t max ],

[0102] θ1-i ∈[0, 180],

[0103] θ 2-i ∈[0, 180].

[0104] Each ablation needle needs to simulate each application parameter according to a preset step size. Furthermore, the step size can be different for different parameters. For example, ablation needle i first applies to W... i Perform traversal, W i If the corresponding power step is 1, then W i The possible values ​​include 0, 1, 2, 3, 4…W max Then ablation targeting θ 1-i Perform traversal, E i The corresponding angle step is 0.5, then θ 1-i The values ​​range from 0, 0.5, 1, 1.5…180. The following iterates over other parameters, which will not be elaborated upon. After iterating over each parameter, the values ​​are combined one by one to obtain a simulation dataset corresponding to each ablation needle. It can be understood that the simulation dataset includes multiple sets of simulated needle application parameters and corresponding simulated regions.

[0105] In operation 1042, to achieve the combination of multiple ablation needles, this method also needs to determine the specific number of ablation needles. Based on the specific number of ablation needles, a simulation dataset corresponding to each ablation needle combination is combined one by one to simulate the combination set. For example, if the number of ablation needles is 4, denoted as the first ablation needle, the second ablation needle, the third ablation needle, and the fourth ablation needle, the first ablation needle should have a first simulation dataset, the second ablation needle should have a second simulation dataset, the third ablation needle should have a third simulation dataset, and the fourth ablation needle should have a fourth simulation dataset. A first simulation dataset is extracted from the first simulation dataset and combined with each set of second simulation data from the second simulation dataset, each set of third simulation data from the third simulation dataset, and each set of fourth simulation data from the fourth simulation dataset. A simulation combination contains one set of first simulation data, one set of second simulation data, one set of third simulation data, and one set of fourth simulation data. The combination of needle application parameters corresponding to the simulation data is the needle application parameter set, and the combination of ablation regions corresponding to the simulation data is the combined ablation region.

[0106] Specifically, it can be represented by the following relationship:

[0107] S {n} =f4(W {n} d {n} , t {n} θ 1-{n} θ 2-{n} ) = argmax((S A∩S {n} )-λ×(S H ∩S {n} ))

[0108] wherein n is the total number of ablation needles, {n} is used to represent the set corresponding to each ablation needle, S A is used to represent the target ablation region.

[0109] In operation 1043 and operation 1044, the combined ablation region can be filtered according to the target ablation region, and the filtering condition is the same as that of the maximum ablation region, that is, the combined ablation region also needs to meet the condition of covering the target ablation region as much as possible and not affecting the target reserved region. The combined ablation region corresponding to the combined ablation parameter set that meets the condition can be used to determine the specific ablation parameter set corresponding to each ablation needle. Specifically, in the case where the combined ablation parameter set can be used to determine the specific ablation parameter set corresponding to each ablation needle, the ablation center corresponding to the ablation needle also needs to be determined to realize the ablation positioning of the ablation needle.

[0110] According to an embodiment of the present application, the method further comprises: first, determining the specific ablation region corresponding to the ablation needle according to the specific ablation parameter set corresponding to the ablation needle; and then, determining the ablation center corresponding to the ablation needle according to the specific ablation region.

[0111] In the case where the specific ablation parameter set corresponding to the ablation needle and the specific ablation region are obtained, the ablation center of the specific ablation region is calculated to correspond to the coordinate point in the Cartesian coordinate system, which is the point where the temperature source of the ablation needle is generated, and is usually the vertex of the ablation needle.

[0112] Specifically, the method for finding the ablation center (x, y, z) is to determine the ablation center (x, y, z) in the formed specific ablation region point set (X, Y, Z) by the following formula:

[0113] x=(Xmax-Xmin)

[0114] y=(Ymax-Ymin)

[0115] z=(Zmax-Zmin)

[0116] wherein Xmax is the maximum X-axis coordinate, Xmin is the minimum X-axis coordinate; Ymax is the maximum Y-axis coordinate, Ymin is the minimum Y-axis coordinate; Zmax is the maximum Z-axis coordinate, and Zmin is the minimum Z-axis coordinate.

[0117] Similarly, the ablation center of the ablation region corresponding to each ablation needle can be determined according to the above method.

[0118] To facilitate further understanding of the above embodiments, the following provides several specific implementation scenarios for supplementary explanation.

[0119] Figure 3 An implementation scenario of a global ablation simulation method for ablation needles is shown Figure 1 .

[0120] In a first implementation scenario, a target ablation region is shown as including a plurality of ellipsoidal shapes that are spliced together Figure 3 . The target ablation region has geometric centers X11, X12, and X13. The number of preset ablation needles is three. The method first performs parameter simulation on the target ablation region according to temperature distribution values to determine a maximum needle application parameter set. The ablation needle combination includes one or more ablation needles. Then, each ablation needle performs parameter traversal in the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle based on the coverage between the obtained simulation region and the target ablation region, and then controls the corresponding ablation needle to perform ablation on the target ablation region according to the specific needle application parameter set corresponding to each ablation needle. Specifically, in the method, the three ablation needles reach X11, X12, and X13 along the geometric center axis, and perform ablation on the target ablation region with X11, X12, and X13 as the ablation centers.

[0121] Figure 4 An implementation module schematic diagram of a global ablation simulation device for ablation needles is shown.

[0122] According to the second aspect of the present application, a global ablation simulation device for ablation needles is provided, as shown in Figure 4 . The device includes a region simulation module 401 configured to simulate a target ablation region according to target ablation tissue; a temperature field simulation module 402 configured to simulate a temperature field according to the target ablation region to obtain temperature distribution values; a parameter simulation module 403 configured to perform parameter simulation on an ablation needle combination according to the temperature distribution values to determine a maximum needle application parameter set; the ablation needle combination includes one or more ablation needles; and a traversal module 404 configured to perform parameter traversal on each ablation needle according to the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle.

[0123] According to an embodiment of the present application, the device further includes an output module 406 configured to output a corresponding simulation needle application scheme according to the specific needle application parameter set corresponding to each ablation needle.

[0124] According to an embodiment of the present application, the parameter simulation module 403 includes a first determination sub-module 4031 configured to determine a maximum ablation region according to the target ablation region and a target reserved region; and a simulation sub-module 4032 configured to perform parameter simulation on each needle application parameter according to the maximum ablation region to determine a maximum needle application parameter set corresponding to each ablation needle.

[0125] According to an embodiment of the present application, the determining sub-module comprises: determining a target reserved tissue, simulating the target reserved tissue according to the target ablation region to obtain a target reserved region; and determining a maximum ablation region according to the target reserved region and the target ablation region.

[0126] According to an embodiment of the present application, the traversing module 404 comprises: a traversing sub-module 4041 configured to perform parameter traversal on a single ablation needle according to the maximum needle insertion parameter set to determine a simulation data set corresponding to the single ablation needle; wherein the simulation data set comprises a simulation needle insertion parameter set and a corresponding simulation region; a combination sub-module 4042 configured to determine an ablation needle number corresponding to an ablation needle combination, combine the simulation needle insertion parameter set and the corresponding simulation region according to the ablation needle number to determine a simulation combination set; wherein the simulation combination set comprises a combination needle insertion parameter set and a combination ablation region; a second screening sub-module 4043 configured to screen the combination ablation region according to the target ablation region to obtain a combination needle insertion parameter set satisfying a screening condition; and a third determining sub-module 4044 configured to determine a specific needle insertion parameter set corresponding to each ablation needle according to the combination needle insertion parameter set.

[0127] According to an embodiment of the present application, the device further comprises a determining module 405 configured to determine a specific ablation region corresponding to the ablation needle according to the specific needle insertion parameter set corresponding to the ablation needle; and the determining module 405 is further configured to determine an ablation center corresponding to the ablation needle according to the specific ablation region.

[0128] It should be noted that the above description of the embodiment of the device for global ablation simulation of an ablation needle is similar to the description of the above-mentioned embodiment of the method, has similar beneficial effects to the above-mentioned embodiment of the method, and thus will not be described again. For technical details not disclosed in the embodiment of the device for global ablation simulation of an ablation needle, please refer to the description of the above-mentioned embodiment of the method, and thus will not be described again. Figures 1 to 3 The embodiment of the device for global ablation simulation of an ablation needle has similar beneficial effects to the above-mentioned embodiment of the method, and thus will not be described again. Figures 1 to 3 The embodiment of the device for global ablation simulation of an ablation needle has similar beneficial effects to the above-mentioned embodiment of the method, and thus will not be described again. Figures 1 to 3 The embodiment of the device for global ablation simulation of an ablation needle has similar beneficial effects to the above-mentioned embodiment of the method, and thus will not be described again.

[0129] According to a third aspect of the embodiment of the present application, a computer device is provided, comprising: a memory, a processor, and a computer program stored in the memory and executable on the processor, and the processor executes the program to implement the above-mentioned method for global ablation simulation of an ablation needle.

[0130] Figure 5 An implementation structure schematic diagram of the computer device according to the embodiment of the present application is shown.

[0131] The implementation structure schematic diagram of the computer device according to the embodiment of the present application is shown. Figure 5According to the third aspect of the present application, there is further provided a computer device comprising a memory, a processor and a computer program stored in the memory and capable of running on the processor, wherein the processor implements any of the above global ablation simulation methods for an ablation needle when executing the program.

[0132] At the hardware level, the device comprises a processor 501, and optionally further comprises an internal bus 503, a network interface 504 and a memory 502. The memory 502 can comprise a memory such as a high-speed Random-Access Memory (RAM), and can further comprise a non-volatile memory such as at least one disk memory. Of course, the device can further comprise other hardware required by the business.

[0133] The processor 501, the network interface 504 and the memory 502 can be connected to each other through the internal bus 503, which can be an Industry Standard Architecture (ISA) bus, a Peripheral Component Interconnect (PCI) bus or an Extended Industry Standard Architecture (EISA) bus, etc. The bus can be divided into an address bus, a data bus and a control bus, etc. For the convenience of representation, only one bidirectional arrow is used in the figure, but it does not mean that there is only one bus or only one type of bus.

[0134] The memory 502 is used to store execution instructions. Specifically, the execution instructions are computer programs that can be executed. The memory 502 can comprise a memory and a non-volatile memory, and provides the processor with execution instructions and data.

[0135] In one possible implementation, the processor 501 reads the corresponding execution instructions from the non-volatile memory into the memory and then runs, and can also obtain the corresponding execution instructions from other devices to form a global ablation simulation device for an ablation needle at the logical level. The processor executes the execution instructions stored in the memory to implement the global ablation simulation method for an ablation needle provided in any of the embodiments of the present application through the executed execution instructions.

[0136] The above as the present application Figure 4The method provided by the embodiment shown for the global ablation simulation device of the ablation needle can be applied to the processor 501 or implemented by the processor 501. The processor 501 can be an integrated circuit chip with a signal processing capability. In the implementation process, each step of the above method can be completed by the integrated logic circuit of hardware in the processor 501 or the instruction in the form of software. The processor mentioned above can be a general processor, including a central processing unit (CPU), a network processor (NP), etc.; and can also be a digital signal processor (DSP), an application specific integrated circuit (ASIC), a field-programmable gate array (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components. Each method, step and logic block disclosed in the embodiment of the present application can be implemented or executed. The general processor can be a microprocessor or the processor can also be any conventional processor.

[0137] The steps of the method disclosed in the embodiment of the present application can be directly embodied as hardware decoding processor execution completion or combined execution completion by hardware and software modules in the decoding processor. The software module can be located in a random memory, a flash memory, a read-only memory, a programmable read-only memory, an electrically erasable programmable memory, a register or other mature storage medium in the field. The storage medium is located in the memory, and the processor 501 reads the information in the memory 502 and combines the hardware to complete the steps of the above method.

[0138] According to the fourth aspect of the present application, a storage medium containing computer executable instructions is further provided, and the computer executable instructions are used to execute the global ablation simulation method for the ablation needle when executed by a computer processor.

[0139] The embodiment of the present application further provides a computer readable storage medium, which stores execution instructions. When the stored execution instructions are executed by a processor of an electronic device, the electronic device can execute the dynamic simulation method for the ablation needle provided in any embodiment of the present application, and is specifically used to execute the method shown above. Figures 1 to 3 The electronic device in each of the foregoing embodiments can be a computer.

[0140] Those skilled in the art shall understand that the embodiments of the present application can be provided as a method or a computer program product. Therefore, the present application can adopt a complete hardware embodiment, a complete software embodiment or a combination of software and hardware.

[0141] The various embodiments in the present application are described in a progressive manner, and the same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on the difference from other embodiments. In particular, for the device embodiments, since they are basically similar to the method embodiments, the description is relatively simple, and the relevant parts can be referred to the part of the method embodiments.

[0142] It should be noted that, in this document, the terms "comprise", "comprising", or any other variant thereof are intended to cover non-exclusive inclusions, so that a process, method, article, or device that includes a list of elements does not only include those elements, but also includes other elements not explicitly listed, or further includes elements inherent in such a process, method, article, or device. Without more limitations, the element defined by the statement "comprises a" does not exclude the presence of additional identical elements in the process, method, article, or device that includes the element.

[0143] In several embodiments provided in the present application, it should be understood that the disclosed devices and methods can be implemented in other ways. The device embodiments described above are only schematic. For example, the division of the units is only a logical function division, and actual implementation can have another division manner, such as: multiple units or components can be combined, or can be integrated into another system, or some features can be ignored or not executed. In addition, the coupling or direct coupling or communication connection between the displayed or discussed components can be through some interface, indirect coupling or communication connection between devices or units, which can be electrical, mechanical or other forms.

[0144] The units described above as separate components can or can not be physically separated, and the components displayed as units can or can not be physical units; they can be located in one place or distributed on multiple network units; and part or all of the units can be selected according to actual needs to achieve the purpose of the present embodiment.

[0145] In addition, each functional unit in each embodiment of the present application can be integrated into one processing unit, or each unit can be a separate unit, or two or more units can be integrated into one unit; the integrated unit can be realized in the form of hardware or in the form of hardware plus software functional unit.

[0146] Those skilled in the art can understand that all or part of the steps of the above-mentioned method embodiments can be completed by program instruction related hardware, and the foregoing program can be stored in a computer readable storage medium, and the program executes the steps of the above-mentioned method embodiments when executed; and the foregoing storage medium includes a mobile storage device, a read only memory (ROM), a magnetic disc or an optical disc and various storage medium capable of storing program codes.

[0147] Alternatively, the integrated unit of the present application can be stored in a computer readable storage medium if it is realized in the form of a software function module and sold or used as an independent product. Based on such understanding, the technical solutions of the embodiments of the present application can be embodied in the form of a software product, and the computer software product is stored in a storage medium, includes several instructions to make a computer device (which can be a personal computer, a server, or a network device, etc.) execute all or part of the methods described in the embodiments of the present application. The foregoing storage medium includes a mobile storage device, a ROM, a magnetic disc or an optical disc and various storage medium capable of storing program codes.

[0148] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto, any person skilled in the art can easily think of changes or replacements within the technical range disclosed by the present application, which should be covered in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A method for global ablation simulation of an ablation needle, characterized in that, The method comprises: According to the target ablation tissue, simulate the target ablation region; According to the target ablation region, perform temperature field simulation to obtain temperature distribution value; According to the temperature distribution value, perform parameter simulation on the ablation needle combination to determine the maximum needle parameter set corresponding to the ablation needle combination as a whole; The ablation needle combination contains one or more ablation needles; The maximum needle parameter set is a set of upper and lower limits of each needle parameter value of each ablation needle in the ablation needle combination corresponding to the target ablation region; According to the maximum needle parameter set, perform parameter traversal on each ablation needle in the ablation needle combination to determine the specific needle parameter set corresponding to each ablation needle in the ablation needle combination; Wherein, the specific needle parameter set is the optimal needle parameter of each ablation needle when the target ablation region needs to be globally ablated by the ablation needle combination; The optimal needle parameter is the needle parameter corresponding to the ablation region of the ablation needle combination covering the target ablation region and not covering the target reserved region; The target reserved region is the tissue region around the target ablation tissue which is avoided to be ablated.

2. The method of claim 1, wherein, After determining the specific needle parameter set corresponding to each ablation needle, the method further comprises: According to the specific needle parameter set corresponding to each ablation needle, output the corresponding simulation needle scheme.

3. The method of claim 1, wherein, According to the temperature distribution value, perform parameter simulation on the ablation needle combination to determine the maximum needle parameter set, comprising: Determine the maximum ablation region according to the target ablation region and the target reserved region; According to the maximum ablation region, perform parameter simulation on each needle parameter to determine the maximum needle parameter set corresponding to each ablation needle.

4. The method of claim 3, wherein, According to the target ablation region and the target reserved region to determine the maximum ablation region, comprising: Determine the target reserved tissue; According to the target ablation region, simulate the target reserved tissue to obtain the target reserved region; According to the target reserved region and the target ablation region, perform ablation region simulation to determine the maximum ablation region.

5. The method of claim 1, wherein, According to the maximum needle parameter set, perform parameter traversal on each ablation needle to determine the specific needle parameter set corresponding to each ablation needle, comprising: According to the maximum needle parameter set, perform parameter traversal on a single ablation needle to determine the simulation data set corresponding to the single ablation needle; Wherein, the simulation data set includes a simulation needle parameter set and a corresponding simulation region; Determine the number of ablation needles corresponding to the ablation needle combination, combine the simulation needle parameter set and the corresponding simulation region according to the number of ablation needles to determine the simulation combination set; Wherein, the simulation combination set includes a combination needle parameter set and a combination ablation region; According to the target ablation region, screen the combination ablation region to obtain the combination needle parameter set meeting the screening condition; According to the combination needle parameter set, determine the specific needle parameter set corresponding to each ablation needle.

6. The method of claim 1, wherein, The method further comprises: According to the specific needle parameter set corresponding to the ablation needle, determine the corresponding specific ablation region; According to the specific ablation region, determine the ablation center of the ablation needle.

7. The method according to any one of claims 1 to 6, characterized in that, The needle application parameter set includes ablation needle power, ablation needle size, ablation time and ablation needle angle.

8. A global ablation simulation device for an ablation needle, characterized by The device comprises: a region simulation module for simulating a target ablation region according to target ablation tissue; a temperature field simulation module for temperature field simulation according to the target ablation region to obtain a temperature distribution value; a parameter simulation module for parameter simulation of an ablation needle combination according to the temperature distribution value to determine a maximum needle application parameter set corresponding to the ablation needle combination as a whole; the ablation needle combination contains one or more ablation needles; the maximum needle application parameter set is a set of upper and lower limits of each needle application parameter of each ablation needle in the ablation needle combination corresponding to the target ablation region; a traversal module for parameter traversal of each ablation needle in the ablation needle combination according to the maximum needle application parameter set to determine a specific needle application parameter set corresponding to each ablation needle in the ablation needle combination; wherein the specific needle application parameter set is a plurality of needle application parameters corresponding to each ablation needle when global ablation of the target ablation region is required through the ablation needle combination; the optimal needle application parameter of the ablation needle combination is the needle application parameter corresponding to the ablation region of the ablation needle combination covering the target ablation region and not covering the target reserved region; the target reserved region is a tissue region around the target ablation tissue to be avoided from being ablated.

9. A computer device comprising: Memory, a processor and a computer program stored in the memory and executable on the processor, characterized in that the processor implements the method of any one of claims 1-7 when executing the program.

10. A storage medium containing computer executable instructions for performing the method of any one of claims 1-7 when executed by a computer processor.

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