Hematology Analyzer Specific Protein Testing System

Abstract

The present invention discloses a specific protein testing system for a blood cell analyzer, wherein the specific protein testing system for a blood cell analyzer includes: an analyzer body, a reagent processing module, a signal acquisition module, a storage module, and a sampling module. The reagent processing module is provided with a reaction cup; the reaction cup body forms a reaction chamber, the cavity wall of the reaction chamber is partially provided as a transparent optical detection wall, and the thickness of the transparent optical detection wall is thinner than the thickness of other cavity walls; the signal acquisition module is provided close to the reagent processing module, and can detect the change in turbidity of the reagent during the reaction process in the reaction chamber through the transparent optical detection wall; the storage module is provided with a storage container; the sampling module can be movably provided on the analyzer body, and the sampling module includes a movable component and a second sampling needle, and the second sampling needle can distribute the reagent from the storage module to the reaction cup through the movable component. The technical solution of the present invention can improve the detection efficiency of the analyzer equipment.

Description

Technical Field

[0001] The present invention relates to the technical field of specific protein testing, and in particular to a specific protein testing system for a blood cell analyzer. Background Art

[0002] In existing analyzers, cell testing and analysis often requires multiple steps. The more steps there are, the more complex the analyzer becomes. Often, a single device can only test a single test item. This reduces testing efficiency and increases wait times for test results. Furthermore, when multiple tests are required, more equipment is required, increasing costs. Summary of the Invention

[0003] The main purpose of the present invention is to provide a specific protein testing system for a blood cell analyzer, which aims to improve the detection efficiency of the analyzer equipment and can simultaneously complete cell counting, classification, and CRP or SAA detection.

[0004] To achieve the above-mentioned objectives, the present invention proposes a specific protein testing system for a blood cell analyzer, comprising: an analyzer body, a reagent processing module, a signal acquisition module, a storage module, and a sampling module. The reagent processing module is disposed on the analyzer body and is provided with a reaction cup; the reaction cup body forms a reaction chamber, the cavity wall of which is provided as a transparent optical detection wall, the thickness of which is thinner than the thickness of other cavity walls; the signal acquisition module is disposed on the analyzer body and is arranged near the reagent processing module, and can detect turbidity changes in the reaction chamber through the transparent optical detection wall; the storage module is disposed on the analyzer body and is provided with a storage container; the sampling module is movably disposed on the analyzer body and includes a movable component and a second sampling needle, the second sampling needle being able to dispense a second sample from the storage module to the reaction cup via the movable component; the reagent processing module includes a pre-mixing module, the reaction cup is movably disposed on the pre-mixing module, and the pre-mixing module reciprocates the reaction cup between the lowering position of the first sampling needle and the lowering position of the second sampling needle.

[0005] Optionally, the reagent processing module includes a reaction structure; the reaction structure includes a reaction cup mounting base, the reaction cup mounting base is fixed to the analyzer body, the reaction cup mounting base is provided with a first mounting groove, the notch of the first mounting groove is opened upward, and at least one reaction cup is detachably installed in the first mounting groove; the signal acquisition module includes a sliding rail, a laser device movably arranged on the sliding rail, and a first stepper motor for driving the laser device to move; the sliding rail is provided on the analyzer body, and is parallel to and spaced apart from the reaction cup mounting base; the reaction cup mounting base is also provided with a signal acquisition hole, the signal acquisition hole is connected to the first mounting groove, the position of the signal acquisition hole corresponds to the transparent light detection wall of the reaction cup, and is opened toward the laser device. The pre-mixing module includes a structural support, a second stepper motor, a fourth synchronous pulley, a fourth synchronous belt, and a sliding member; the second stepper motor is fixed to the structural support, the second stepper motor and the fourth synchronous pulley are spaced apart, and the output shaft of the second stepper motor is connected to the fourth synchronous pulley through the fourth synchronous belt, a sliding guide rail is provided on the top of the structural support, the sliding member is slidably provided on the sliding guide rail, and the sliding member is connected to the fourth synchronous belt; the sliding member is provided with a second mounting groove with an upward opening, and the reaction cup can also be detachably mounted in the second mounting groove; the other end of the sliding guide rail is a sample position for the first sampling needle to transport the first sample; one end of the sliding guide rail is a pre-mixing position for the second sampling needle to transport the second sample and mix it.

[0006] Optionally, it is characterized in that the specific protein testing system of the blood cell analyzer adopts an iterative testing method including: the reaction cup mounting base is provided with at least a first reaction cup and a second reaction cup; when the second sampling needle completes the mixing process of the mixed liquid in the first reaction cup, the first sampling needle and the second sampling needle are in an idle state during the process of complete mixing in the first reaction cup; the second sampling needle in the idle state can mix the second reaction cup; the movable laser device is provided with a signal acquisition period T, and every T time, the laser device can sequentially collect turbidity values in the first reaction cup and / or the second reaction cup.

[0007] Optionally, the reaction chamber has an upwardly arranged liquid inlet and a downwardly arranged liquid outlet; the cavity wall of the reaction chamber is gradually narrowed downward, and the cavity wall of the reaction chamber is connected to the side wall of the liquid outlet through an arc side wall.

[0008] Optionally, the cuvette further comprises an elastic clip, one end of which is connected to the outer peripheral surface of the cuvette body, and the other end of which extends in a direction away from the cuvette body;

[0009] At least one clamping protrusion is formed on a side of the elastic clamping rib facing away from the cup body.

[0010] Optionally, a stirring vibration member is further provided at the position where the second sampling needle is connected to the movable component.

[0011] Optionally, the movable component includes an elastic member, one end of the second sampling needle is connected to the elastic member, and the elastic member is also provided with a sensor, which is electrically connected to the movable component; when the second sampling needle strikes the needle, the elastic member is compressed and triggers the sensor to control the movable component to stop moving, so as to prevent the second sampling needle from seriously striking the needle and avoid damage to the second sampling needle.

[0012] Optionally, the storage module is divided into a normal temperature storage area and a refrigerated storage area; the normal temperature storage area includes a CRP buffer tank, a treatment liquid tank and an SAA buffer tank; the refrigerated storage area includes a CRP latex tank and an SAA latex tank.

[0013] Optionally, the movable assembly further includes a mounting base and a vertical motion mechanism, a rotary motion mechanism, and a horizontal motion mechanism sequentially connected upward from the mounting base; the vertical motion mechanism includes a vertically movable rotating rod, the rotary rod is connected to the rotary motion mechanism, the rotary motion mechanism includes a rotatable rotating disk, and the rotating disk is connected to the horizontal motion mechanism; the second sampling needle is movably arranged in the horizontal motion mechanism.

[0014] Optionally, the vertical motion mechanism further includes a vertical motor, a first synchronous pulley, a first synchronous belt, and a vertical slider; the vertical motor and the first synchronous pulley are spaced apart in the height direction, the output end of the vertical motor is connected to the first synchronous pulley through the first synchronous belt, the vertical slider is arranged on the first synchronous belt, the rotating rod is fixed to the vertical slider, and one end of the rotating rod extends along the height direction of the mounting base; and / or the rotary motion mechanism further includes a fixing member, a rotary motor, and a second synchronous belt; the fixing member is fixed to one end of the rotary rod away from the vertical slider, the rotary motor is arranged on the fixing member, and the output end of the rotary motor It is connected to the rotating disk through the second synchronous belt; and / or the horizontal motion mechanism also includes a horizontal motor, a sliding platform, a horizontal slider, a third synchronous pulley, and a third synchronous belt; the horizontal motor is fixedly connected to the rotating disk, a side wall of the horizontal motor is provided with the sliding platform, the sliding platform is provided with a sliding groove, the sliding groove extends in the horizontal direction, the horizontal slider is movably arranged in the sliding groove, the sliding platform is provided with the third synchronous pulley at one end away from the horizontal motor, the output end of the horizontal motor is connected to the third synchronous pulley through the third synchronous belt, the horizontal slider is provided on the third synchronous belt, and the horizontal slider is fixed with the second sampling needle.

[0015] Optionally, the specific protein testing system of the blood cell analyzer also includes a cleaning system; the cleaning system has a waste liquid discharge liquid path and a sampling needle cleaning liquid path; the waste liquid discharge liquid path is provided with a waste liquid pump and is connected to the reaction cup, and the waste liquid pump discharges the waste liquid in the reaction cup to the specific protein testing system of the blood cell analyzer; the sampling needle cleaning liquid path includes a diluent storage device, a diluent pump, a syringe and a water bath, and the diluent is injected from the diluent storage device via the diluent pump and the syringe from the second sampling needle into the water bath, and the diluent can also be directly injected from the diluent storage device into the water bath by the diluent pump.

[0016] The technical solution of the present invention uses a reagent processing module to insert the first sample collected by the first sampling needle and the second sample collected by the second sampling needle into the reagent processing module for mixing, thereby obtaining the required test sample. Specifically, the reaction cup is used to contain samples, reagents and other liquids involved in the reaction. The cavity wall of the reaction chamber is configured as a transparent light detection wall. The signal acquisition module obtains the presence or absence of the test sample in the reaction cup and various parameters of the test sample through the transparent light detection wall of the reaction cup. The storage module is pre-placed with the second sample, and the second sampling needle can directly take out the second sample from the storage module and add it into the reaction cup, so as to achieve faster mixing of the first sample and the second sample, thereby improving the mixing efficiency of the samples in the analyzer and also improving the efficiency of the analyzer detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0018] Figure 1 This is a schematic structural diagram of an embodiment of a specific protein testing system for a blood cell analyzer according to the present invention;

[0019] Figure 2 This is a schematic diagram of the sampling module structure of the specific protein testing system of the blood cell analyzer of the present invention;

[0020] Figure 3 This is a schematic diagram of the structure of the signal acquisition module of the specific protein testing system of the blood cell analyzer of the present invention;

[0021] Figure 4 A cross-sectional view of a cuvette mounting base and a cuvette of a specific protein testing system of a hematology analyzer according to the present invention;

[0022] Figure 5 This is a schematic structural diagram of the pre-mixing module of the specific protein testing system of the blood cell analyzer of the present invention;

[0023] Figure 6 This is a fluid circuit diagram of the specific protein testing system of the hematology analyzer of the present invention.

[0024] Description of Figure Numbers:

[0025] Label name Label name 1 Analyzer body 2 Reagent processing module 21 reaction cup 211 reaction chamber 212 Transparent light inspection wall 213 Liquid inlet 214 Liquid outlet 215 Elastic clip 22 Reaction structure 221 Reaction cup mounting base 222 First mounting groove 223 Signal collection hole 23 Premixing module 231 Structural support 232 Second stepper motor 233 Fourth synchronous pulley 234 Fourth synchronous belt 235 Sliders 236 Sliding rails 237 Second mounting groove 3 Signal acquisition module 4 Storage Module 41 Normal temperature storage area 42 Refrigerated storage area 5 Sampling Module 51 Active Components 52 Second sampling needle 53 Stirring vibration parts 511 Mounting Base 512 Vertical motion mechanism 512-1 Vertical motor 512-2 Vertical Slider 512-3 First synchronous belt 512-4 First synchronous pulley 512-5 Rotating rod 513 Rotary motion mechanism 513-1 rotating disk 513-2 Fixing parts 513-3 Rotating electric machines 513-4 Second synchronous belt 514 Horizontal motion mechanism 514-1 Horizontal motor 514-2 Sliding platform 514-3 Horizontal Slider 514-4 The third synchronous pulley 514-5 The third synchronous belt 6 Premixing 7 Sample position

[0026] The purpose, features and advantages of the present invention will be further described with reference to the accompanying drawings and in conjunction with the embodiments. DETAILED DESCRIPTION

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0028] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0029] In the present invention, unless otherwise specified or limited, the terms "connection" and "fixation" should be understood in a broad sense. For example, "fixation" can mean fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two elements or interaction between two elements, unless otherwise specified. Those skilled in the art will be able to understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0030] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "and / or" appearing throughout the text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0031] The present invention provides a specific protein testing system for a hematology analyzer.

[0032] Reference Figures 1 to 6In one embodiment of the present invention, the specific protein testing system of the blood cell analyzer includes: an analyzer body 1, a reagent processing module 2, a signal acquisition module 3, a storage module 4 and a sampling module 5. The reagent processing module 2 is provided in the analyzer body 1, and the reagent processing module 2 is provided with a reaction cup 21; the reaction cup body is formed with a reaction chamber 211, and the cavity wall portion of the reaction chamber 211 is provided as a transparent light detection wall 212, and the thickness of the transparent light detection wall 212 is thinner than the thickness of other cavity walls; the signal acquisition module 3 is provided in the analyzer body 1, and is provided close to the reagent processing module 2, and the turbidity change in the reaction chamber 211 can be observed or detected through the transparent light detection wall 212; the storage module 4 is provided in the analyzer body 1, and the storage module 4 is provided with a storage container; a sampling module 5 is movably provided on the analyzer body 1, and the sampling module 5 includes a movable component 51 and a second sampling needle 52, and the second sampling needle 52 can use the movable component 51 to dispense the second sample from the storage module 4 to the reaction cup 21; the reagent processing module 2 includes a pre-mixing module 23, and the reaction cup 21 is movably provided on the pre-mixing module 23, and the pre-mixing module 23 reciprocates the reaction cup 21 between the lower needle position of the first sampling needle and the lower needle position of the second sampling needle 52.

[0033] The technical solution of the present invention uses a reagent processing module 2 to insert the first sample collected by the first sampling needle and the second sample collected by the second sampling needle 52 into the reagent processing module 2 for mixing, thereby obtaining the required test sample. Specifically, the reaction cup 21 is used to hold samples, reagents and other liquids involved in the reaction. The cavity wall portion of the reaction chamber 211 is configured as a transparent optical detection wall 212. The signal acquisition module 3 obtains the presence or absence of the test sample in the reaction cup 21 and various parameters of the test sample through the transparent optical detection wall 212 of the reaction cup 21. The storage module 4 is pre-placed with the second sample, and the second sampling needle 52 can directly take out the second sample from the storage module 4 and add it into the reaction cup 21, so as to achieve faster mixing of the first sample and the second sample, thereby improving the mixing efficiency of the sample in the analyzer and also improving the efficiency of the analyzer detection.

[0034] Furthermore, the reaction chamber 211 has an upwardly disposed liquid inlet 213 and a downwardly disposed liquid outlet; the walls of the reaction chamber 211 are configured to gradually taper downward, and the walls of the reaction chamber 211 are connected to the sidewalls of the liquid outlet via arcuate sidewalls. In this embodiment, the reaction chamber 211 has an upwardly disposed liquid inlet 213, and a sampling needle injects a sample into the reaction chamber 211 from the top of the reaction cup 21 for mixing. The reaction chamber 211 has a downwardly disposed liquid outlet. When the liquid in the reaction chamber 211 is sufficient or excessive, the reaction cup 21 can discharge the excess sample through the liquid outlet. The analyzer can discharge excess sample without removing the reaction cup 21, making the entire device more convenient and simple to use.

[0035] Furthermore, the cuvette 21 includes an elastic retaining rib 215, one end of which is connected to the outer circumference of the cuvette 21 body and the other end of which extends away from the cuvette 21 body. The elastic retaining rib 215 is formed with at least one latching protrusion on a side facing away from the cuvette body. In one embodiment, the cuvette 21 is provided with the elastic retaining rib 215, and the cuvette 21 is removably attached to the reagent processing module 2 via the spring retaining rib. The removable attachment of the cuvette 21 facilitates easy replacement of the cuvette 21, ensuring cleanliness during use and preventing contamination between different samples. However, this embodiment is not limited to having only one latching protrusion; two, three, or more latching protrusions may be provided. One of the latching protrusions secures the cuvette 21 in the reagent processing module 2, while the other latching protrusions act as friction-enhancing structures. During removal of the cuvette 21, the other latching protrusions enhance friction with the hand, facilitating removal of the cuvette 21.

[0036] Furthermore, a stirring vibration member 53 is provided at the connection position between the second sampling needle 52 and the movable assembly 51. To facilitate mixing and testing the sample in the reaction cup 21, a stirring vibration member 53 is provided at the connection position between the second sampling needle 52 and the movable assembly 51. The stirring vibration member 53 vibrates the second sampling needle 52 to stir the sample in the reaction cup 21.

[0037] Furthermore, the movable assembly 51 includes an elastic member, to which one end of the second sampling needle 52 is connected. The elastic member is also provided with a sensor, which is electrically connected to the movable assembly 51. When the second sampling needle 52 strikes the needle, the elastic member is compressed, triggering the sensor to control the movable assembly 51 to stop moving. Specifically, when the second sampling needle 52 strikes the needle, the elastic member is compressed and elastically deforms. The sensor, sensing this elastic deformation, controls the movable assembly 51 to stop moving, thereby preventing damage to the second sampling needle 52.

[0038] Further, refer to Figure 1 The storage module 4 is divided into a normal temperature storage area 41 and a cold storage area 42; the normal temperature storage area 41 includes a CRP (C-reactive protein C-reactive protein) buffer tank, a treatment liquid tank and an SAA (serum amyloid protein) buffer tank; the cold storage area 42 includes a CRP latex tank and an SAA latex tank. The storage module 4 is provided with a normal temperature storage area 41 and a cold storage area 42, which is conducive to storing reaction reagents under different environmental requirements and facilitates the second sampling needle 52 to directly obtain reagents. It should be understood that in this embodiment, the second sample includes CRP buffer, SAA buffer, treatment liquid, CRP latex and SAA latex.

[0039] Furthermore, the movable assembly 51 also includes a mounting base 511, and a vertical motion mechanism 512, a rotational motion mechanism 513, and a horizontal motion mechanism 514 connected sequentially upward from the mounting base 511. The vertical motion mechanism 512 includes a vertically movable rotating rod 512-5, which is connected to the rotational motion mechanism 513. The rotational motion mechanism includes a rotatable rotating disk 513-1, which is connected to the horizontal motion mechanism 514. The second sampling needle 52 is movably mounted on the horizontal motion mechanism 514. The vertical motion mechanism 512, the rotational motion mechanism 513, and the horizontal motion mechanism 514 collectively enable the second sampling needle 52 to freely move in space to a specified position.

[0040] Specifically, refer to Figure 2In one embodiment, the vertical motion mechanism 512 further includes a vertical motor 512-1, a first synchronous pulley 512-4, a first synchronous belt 512-3, and a vertical slider 512-2; the vertical motor 512-1 and the first synchronous pulley 512-4 are spaced apart in the height direction, the output end of the vertical motor 512-1 is connected to the first synchronous pulley 512-4 through the first synchronous belt 512-3, the vertical slider 512-2 is provided on the first synchronous belt 512-3, the rotating rod 512-5 is fixed to the vertical slider 512-2, and one end of the rotating rod extends along the height direction of the mounting base 511. In another embodiment, the rotary motion mechanism 513 further includes a fixing member 513-2, a rotary motor 513-3, and a second synchronous belt 513-4; the fixing member 513-2 is fixed to the end of the rotary rod away from the vertical slider, the rotary motor 513-3 is provided on the fixing member 513-2, and the output end of the rotary motor 513-3 is connected to the rotary disk 513-1 via the second synchronous belt 513-4. In another embodiment, the horizontal motion mechanism 514 further includes a horizontal motor 514-1, a sliding platform 514-2, a horizontal slider 514-3, a third synchronous belt 514-5, a wheel 514-4, and a third synchronous belt 514-5; the horizontal motor 514-1 is fixedly connected to the rotary disk 513-1, a side wall of the horizontal motor 514-1 is provided with the sliding platform 514-2, and the sliding platform 514-2 is provided with a sliding groove, and the sliding groove extends in the horizontal direction. The horizontal slider 514-3 is movably mounted in the sliding groove. The end of the sliding platform 514-2 away from the horizontal motor 514-1 is provided with the third synchronous belt 514-5 pulley 514-4. The output end of the horizontal motor 514-1 is connected to the third synchronous belt 514-5 pulley 514-4 via the third synchronous belt 514-5. The horizontal slider 514-3 is mounted on the third synchronous belt 514-5. The second sampling needle 52 is fixed to the horizontal slider 514-3. In this embodiment, the movable assembly 51 also includes a rotating rod 512-5. The vertical motion mechanism 512 is rotatably connected to the rotating rod 512-5 and provides the rotating rod 512-5 with movement in the ascending and descending directions. The rotating rod 512-5 is also coaxially connected to the rotating disk 513-1. When the rotating motor 513-3 drives the rotating disk 513-1 to rotate, the rotating rod 512-5 can rotate at the same angle as the rotating disk 513-1. A horizontal motor 514 - 1 is fixedly provided at one end of the rotating rod 512 - 5 . The horizontal motor 514 - 1 can rotate as the rotating rod 512 - 5 rotates, and can rise and fall as the rotating rod 512 - 5 rises and falls.

[0041] Further, refer to Figure 3 and Figure 4The reagent processing module 2 includes a reaction structure 22; the reaction structure 22 includes a cuvette mounting base 221. The cuvette mounting base 221 is fixed to the analyzer body 1 and defines a first mounting groove 222. The notch of the first mounting groove 222 faces upward, and at least one cuvette 21 is detachably mounted in the first mounting groove 222. The upward notch of the first mounting groove 222 facilitates the installation of the cuvette 21 in the first mounting groove 222 from top to bottom, making installation of the cuvette 21 simpler and more convenient. The signal acquisition module 3 includes a sliding track, a laser device movably mounted on the sliding track, and a first stepper motor that drives the laser device. The sliding track is located on the analyzer body 1 and is parallel to and spaced apart from the cuvette mounting base 221. The cuvette mounting base 221 also defines a signal acquisition hole 223 that communicates with the first mounting groove 222. The hole 223 is positioned corresponding to the transparent optical detection wall 212 of the cuvette 21 and faces the laser device. The laser device slides on the parallel, spaced-apart sliding track to detect different cuvettes 21 positioned within the first mounting groove 222. Specifically, the laser device detects the background value of the cuvette 21 through the signal acquisition hole 223 on the cuvette mounting base 221 and the transparent optical detection wall 212 of the cuvette 21. This background value detection by the laser device allows vacant cuvettes 21 to be screened for subsequent liquid mixing testing by the sampling needle.

[0042] Further, refer to Figure 5, the reagent processing module 2 also includes a pre-mixing module 23, the pre-mixing module 23 is arranged on the analyzer body 1; the pre-mixing module 23 includes a structural support 231, a second stepping motor 232, a fourth synchronous pulley 233, a fourth synchronous belt 234, and a sliding member 235; the second stepping motor 232 is fixed to the structural support 231, the second stepping motor 232 and the fourth synchronous pulley 233 are spaced apart, and the output shaft of the second stepping motor 232 is connected to the fourth synchronous pulley 233 through the fourth synchronous belt 234, the A sliding guide rail 236 is provided at the top of the structural support 231. The sliding member 235 is slidably mounted on the sliding guide rail 236 and is connected to the fourth synchronous belt 234. The sliding member 235 is provided with a second mounting groove 237 with an upward opening. The reaction cup 21 can also be removably mounted in the second mounting groove 237. The other end of the sliding guide rail 236 is a sample position 7 for the first sampling needle to transport the first sample. One end of the sliding guide rail 236 is a pre-mixing position 6 for the second sampling needle 52 to transport and mix the second sample. Specifically, the first sample is added from the sample position 7 into the reaction cup 21 of the pre-mixing module 23 via the first sampling needle. The reaction cup 21 moves along the sliding guide rail 236 to the pre-mixing position 6. The first sampling needle stirs and mixes the reaction cup 21 located in the pre-mixing position 6 via the stirring vibration member 53.

[0043] A detection method for a specific protein test system of a blood cell analyzer, using the structure of the present application, comprises the following steps:

[0044] The first sampling needle draws a first sample, and the second sampling needle 52 draws the treatment liquid in the treatment liquid tank;

[0045] The signal acquisition module 3 collects the background value of the reaction cup 21 and selects an empty reaction cup 21 for use;

[0046] The sliding member 235 slides to the pre-mixing position 6, and the second sampling needle 52 moves to the pre-mixing position 6 and lowers the needle to discharge the treatment liquid;

[0047] The sliding member 235 slides to the sample position 7 again, and the first sampling needle moves to the sample position 7 and lowers the needle to spit out the first sample;

[0048] The sliding member 235 then slides to the pre-mixing position 6, the second sampling needle 52 is lowered, and the second sampling needle 52 is vibrated. After the first sample and the treatment solution are stirred and mixed, the second sampling needle 52 is raised, completing the pre-treatment of the first sample to obtain a pre-diluted sample;

[0049] The laser device of the signal acquisition module 3 acquires parameters of the pre-diluted sample;

[0050] Cleaning the second sampling needle 52;

[0051] The second sampling needle 52 adds CRP buffer to the reaction cup 21 as a base liquid, and then sequentially draws out CRP buffer, CRP emulsion, and the pre-diluted sample; or the second sampling needle 52 adds SAA buffer to the reaction cup 21 as a base liquid, and then sequentially draws out SAA buffer, SAA emulsion, and the pre-diluted sample;

[0052] The second sampling needle 52 moves to the reaction cup 21 position of the reaction structure 22 and is inserted to discharge the mixed solution of the CRP buffer, the CRP emulsion and the pre-diluted sample or the mixed solution of the SAA buffer, the SAA emulsion and the pre-diluted sample into the reaction cup 21;

[0053] The laser device of the signal acquisition module 3 collects the optical signal in the mixed liquid;

[0054] After signal acquisition is completed, the pre-diluted sample in the reaction cup 21 of the sliding block and the mixed solution in the reaction cup 21 of the reaction structure 22 are discharged and cleaned, and the first sampling needle and the second sampling needle 52 are cleaned, thereby completing a CRP or SAA test.

[0055] It should be understood that when the second sampling needle 52 in the detection method of the specific protein test system of the hematology analyzer performs CRP testing or SAA testing, the order of adding liquids needs to strictly follow the order of buffer solution, emulsion, and pre-diluted sample, because the amount of buffer solution is larger, and the amount of emulsion and pre-diluted sample is tiny compared to the buffer solution. If the emulsion or pre-diluted sample is added first, the buffer solution subsequently sucked in by the second sampling needle 52 will push the previously sucked emulsion or pre-diluted sample upward instead of dissolving it in the buffer solution, and the final mixed liquid will not meet the detection standard.

[0056] The hematology analyzer specific protein testing system adopts an iterative testing method including:

[0057] The reaction cup mounting base is provided with at least a first reaction cup and a second reaction cup;

[0058] After the second sampling needle completes the mixing process of the mixed liquid in the first reaction cup, the first sampling needle and the second sampling needle are in an idle state during the process of complete mixing in the first reaction cup;

[0059] The second sampling needle in an idle state can mix the second reaction cup;

[0060] The movable laser device is provided with a signal collection period T. Every T time, the laser device can sequentially collect the turbidity value in the first reaction cup and / or the second reaction cup.

[0061] After using the iterative testing method, the testing speed of the design scheme of the present invention is greatly improved, and multiple reaction cups can be mixed in a short time.

[0062] refer to Figure 6 In one embodiment, the specific protein testing system of the blood cell analyzer also includes a waste liquid discharge liquid path and a sampling needle cleaning liquid path connected by pipelines. The cleaning structure includes a syringe, which is connected to the sampling needle, and the syringe injects a diluent into the sampling needle at a uniform speed to achieve the effect of cleaning the inner wall of the sampling needle. In addition, the sampling needle is inserted into the water bath to enable the system to clean the outer wall of the sampling needle. Furthermore, the reaction cup 21 can discharge the waste liquid accumulated in the reaction cup 21 through the liquid outlet 214 at the bottom. The coolant used for the tank body in the storage module 4 can also be discharged through the pipeline connected to the bottom of the tank body.

[0063] Specifically, in this embodiment, the waste liquid discharge liquid circuit is provided with a waste liquid pump and is connected to the reaction cup. The waste liquid pump discharges the waste liquid in the reaction cup to the specific protein testing system of the blood cell analyzer; the sampling needle cleaning liquid circuit includes a diluent storage device, a diluent pump, a syringe and a water bath. The diluent is injected from the diluent storage device via the diluent pump and the syringe from the second sampling needle into the water bath. The diluent can also be directly injected from the diluent storage device into the water bath by the diluent pump.

[0064] The above descriptions are merely optional embodiments of the present invention and do not limit the patent scope of the present invention. All equivalent structural transformations made using the contents of the present description and drawings under the inventive concept of the present invention, or direct / indirect applications in other related technical fields, are included in the patent protection scope of the present invention.

Claims

1. A specific protein testing system for a blood cell analyzer, comprising a blood sampling module, wherein the blood sampling module comprises a first sampling needle for collecting a first sample, characterized in that: The blood cell analyzer specific protein testing system also includes: Analyzer body; A reagent processing module is provided in the analyzer body, and the reagent processing module is provided with a reaction cup; the reaction cup body forms a reaction cavity, and the cavity wall of the reaction cavity is provided as a transparent optical detection wall, and the thickness of the transparent optical detection wall is thinner than the thickness of other cavity walls; a signal acquisition module, which is provided in the analyzer body and is close to the reagent processing module and can detect turbidity changes in the reaction chamber through the transparent optical detection wall; a storage module, provided in the analyzer body, wherein the storage module is provided with a storage container; and a sampling module movably disposed on the analyzer body, the sampling module comprising a movable assembly and a second sampling needle, the second sampling needle delivering the second sample from the storage module to the reaction cup via the movable assembly; The reagent processing module includes a pre-mixing module, the reaction cup is movably arranged in the pre-mixing module, and the pre-mixing module reciprocates the reaction cup between the lower needle position of the first sampling needle and the lower needle position of the second sampling needle; The cuvette further includes an elastic clip, one end of which is connected to the outer peripheral surface of the cuvette body and the other end of which extends in a direction away from the cuvette body; At least one latching protrusion is formed on a side of the elastic latching rib facing away from the cup body; The reagent processing module includes a reaction structure; the reaction structure includes a reaction cup mounting base, the reaction cup mounting base is fixed to the analyzer body, the reaction cup mounting base is provided with a first mounting groove, the notch of the first mounting groove is opened upward, and at least one reaction cup is detachably mounted in the first mounting groove; The signal acquisition module includes a sliding track, a laser device movably arranged on the sliding track, and a first stepper motor for driving the laser device to move; the sliding track is arranged on the analyzer body and is parallel to and spaced from the reaction cup mounting base; The cuvette mounting base is further provided with a signal collection hole, the signal collection hole being in communication with the first mounting groove, the position of the signal collection hole corresponding to the transparent optical inspection wall of the cuvette, and being opened toward the laser device; The hematology analyzer specific protein testing system adopts an iterative testing method including: The reaction cup mounting base is provided with at least a first reaction cup and a second reaction cup; After the second sampling needle completes the mixing process of the mixed liquid in the first reaction cup, the first sampling needle and the second sampling needle are in an idle state during the process of complete mixing in the first reaction cup; The second sampling needle in an idle state can mix the second reaction cup; The movable laser device is provided with a signal collection period T. Every T time, the laser device can sequentially collect the turbidity value in the first reaction cup and / or the second reaction cup.

2. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The pre-mixing module includes a structural support, a second stepper motor, a fourth synchronous pulley, a fourth synchronous belt, and a sliding member; the second stepper motor is fixed to the structural support, the second stepper motor and the fourth synchronous pulley are spaced apart, and the output shaft of the second stepper motor is connected to the fourth synchronous pulley through the fourth synchronous belt, a sliding guide rail is provided on the top of the structural support, the sliding member is slidably provided on the sliding guide rail, and the sliding member is connected to the fourth synchronous belt; The sliding member is provided with a second mounting groove with an upward opening, and the reaction cup can be detachably mounted in the second mounting groove; One end of the sliding guide rail is a pre-mixing position for the second sampling needle to transport the second sample and mix it; the other end of the sliding guide rail is a sample position for the first sampling needle to transport the first sample.

3. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The reaction chamber has an upwardly arranged liquid inlet and a downwardly arranged liquid outlet; the cavity wall of the reaction chamber is gradually reduced downward, and the cavity wall of the reaction chamber is connected to the side wall of the liquid outlet through an arc side wall.

4. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: A stirring vibration member is also provided at the position where the second sampling needle is connected to the movable component.

5. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The movable component includes an elastic member, one end of the second sampling needle is connected to the elastic member, and the elastic member is further provided with a sensor, and the sensor is electrically connected to the movable component; When the second sampling needle strikes the needle, the elastic member is compressed and triggers the sensor to control the movable component to stop moving.

6. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The storage module is divided into a normal temperature storage area and a refrigerated storage area; The normal temperature storage area includes a CRP buffer tank, a treatment liquid tank and an SAA buffer tank; The refrigerated storage area includes a CRP latex tank body and a SAA latex tank body.

7. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The movable assembly further includes a mounting base, and a vertical motion mechanism, a rotational motion mechanism, and a horizontal motion mechanism sequentially connected upward from the mounting base; The vertical motion mechanism includes a vertically movable rotating rod, which is connected to the rotating motion mechanism. The rotating motion mechanism includes a rotatable rotating disk, which is connected to the horizontal motion mechanism. The second sampling needle is movably arranged on the horizontal motion mechanism.

8. The specific protein testing system for a blood cell analyzer according to claim 7, wherein: The vertical motion mechanism further includes a vertical motor, a first synchronous pulley, a first synchronous belt, and a vertical slider; the vertical motor and the first synchronous pulley are spaced apart in the height direction, the output end of the vertical motor is connected to the first synchronous pulley through the first synchronous belt, the vertical slider is provided on the first synchronous belt, the rotating rod is fixed to the vertical slider, and one end of the rotating rod extends along the height direction of the mounting base; and / or The rotary motion mechanism further includes a fixing member, a rotary motor, and a second synchronous belt; the fixing member is fixed to the end of the rotary rod away from the vertical slider, the rotary motor is provided on the fixing member, and the output end of the rotary motor is connected to the rotary disk via the second synchronous belt; and / or The horizontal motion mechanism also includes a horizontal motor, a sliding platform, a horizontal slider, a third synchronous pulley, and a third synchronous belt; the horizontal motor is fixedly connected to the rotating disk, a side wall of the horizontal motor is provided with the sliding platform, the sliding platform is provided with a sliding groove, the sliding groove extends in the horizontal direction, the horizontal slider is movably arranged in the sliding groove, the sliding platform is provided with the third synchronous pulley at one end away from the horizontal motor, the output end of the horizontal motor is connected to the third synchronous pulley through the third synchronous belt, the horizontal slider is provided on the third synchronous belt, and the horizontal slider is fixed with the second sampling needle.

9. The specific protein testing system for a blood cell analyzer according to claim 1, wherein: The specific protein testing system of the hematology analyzer further includes a cleaning system; The cleaning system has a waste liquid discharge liquid path and a sampling needle cleaning liquid path; the waste liquid discharge liquid path is provided with a waste liquid pump and is connected to the reaction cup, and the waste liquid pump discharges the waste liquid in the reaction cup to the specific protein testing system of the blood cell analyzer; the sampling needle cleaning liquid path includes a diluent storage device, a diluent pump, a syringe and a water bath, and the diluent is injected from the diluent storage device through the diluent pump and the syringe from the second sampling needle into the water bath, and the diluent can also be directly injected from the diluent storage device into the water bath by the diluent pump.

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