Automated analysis device

Abstract

An automatic analysis device is provided. The automatic analysis device is an automatic analysis device for sequentially analyzing a plurality of specimens. The automatic analysis device includes a transport section that transports a container for housing a specimen, a measurement section that sequentially measures the specimen transported by the transport section, a control section that controls the transport section so as to transport the container to the measurement section in a prescribed order, and a notification section that notifies of a transport state of the container controlled by the control section. In a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify of a timing at which a user can access a prescribed area of the automatic analysis device.

Description

TECHNICAL FIELD

[0001] The present disclosure relates to an automatic analysis device. BACKGROUND

[0002] There is known a blood coagulation analysis that injects a reagent into a reaction container (hereinafter, referred to as a "cuvette") into which a blood component or a urine or the like is dispensed, and measures scattered light or transmitted light when light is irradiated, thereby performing analysis of a coagulation function and a fibrinolysis function of the sample.

[0003] As such a method of blood coagulation analysis, there are known a method of measuring a coagulation time and a colorimetric method. The former is a method of irradiating light to a cuvette into which a sample and a reagent are injected, and calculating a coagulation time of each item from a process of change in intensity of scattered light. The latter is a method of irradiating light of a specific wavelength to a cuvette into which a sample and a reagent are injected and measuring absorbance, and calculating a concentration or an activity value of each item from absorbance after a prescribed time or a change amount of absorbance within a prescribed time. Further, the colorimetric method is sometimes referred to as an absorbance measurement method.

[0004] Japanese Patent Application Publication No. 2017-111050 (Patent Literature 1) discloses an automatic analysis device that analyzes a sample housed in a container using a reagent housed in a reagent container. In the automatic analysis device as disclosed in Patent Literature 1, various sensors are provided in order to detect abnormalities related to suction of a probe or the like used when dispensing a reagent, a sample, and the like, abnormalities related to transport of a container or the like, and a liquid residual amount shortage of a reagent, and the like. Among the abnormalities detected by these sensors, there are abnormalities that cause an interrupt process that enables analysis to continue, and abnormalities that cause an emergency stop that does not enable analysis to continue.

[0005] PRIOR ART DOCUMENTS

[0006] PATENT LITERATURE

[0007] Patent Literature 1: Japanese Patent Application Publication No. 2017-111050 SUMMARY

[0008] PROBLEMS TO BE SOLVED BY THE INVENTION

[0009] In a case where a sensor detects an abnormality that causes an interrupt process that enables analysis to continue, the automatic analysis device interrupts sampling of a new sample, but processes a sample sampled before the abnormality is detected until analysis is performed. Therefore, the automatic analysis device restricts access to a prescribed area of the device during a period from when the abnormality is detected until analysis processing of the sample sampled before the abnormality is detected is performed.

[0010] In a case where an abnormality is detected, the user needs to access a prescribed area of the device to eliminate the cause of the abnormality, but does not know to what extent of time to wait before being able to access the prescribed area. In particular, in a case where processing is interrupted due to an abnormality such as a shortage of the liquid amount of a reagent, the user needs to interrupt the operation and wait until being able to access the prescribed area (e.g., the lid of a reagent dispensing device) of the device each time, and there is a problem that the operation efficiency is significantly reduced.

[0011] The present disclosure was completed in view of the above-described actual situation, and one of the objects thereof is to provide an automatic analysis device that does not reduce the operation efficiency even if an abnormality that causes interrupted processing that enables analysis to be continued occurs.

[0012] Solution to Problem

[0013] The automatic analysis device of the present disclosure is an automatic analysis device for sequentially performing analysis on a plurality of specimens, and includes: a conveying section that conveys a container for housing a specimen; a measuring section that sequentially measures the specimen conveyed by the conveying section; a control section that controls the conveying section so that the container is conveyed to the measuring section in a prescribed order; and a notification section that notifies of a conveying state of the container controlled by the control section. In a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify of a timing at which the user can access a prescribed area of the automatic analysis device.

[0014] Effects of the Invention

[0015] According to the present disclosure, in a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify of a timing at which the user can access a prescribed area of the automatic analysis device, and therefore the user effectively uses the time until the timing at which the prescribed area can be accessed, and thus the operation efficiency is not reduced. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is a diagram showing a control system of an analysis device.

[0017] Figure 2 is a diagram showing a structure in which conveying and disposal of cuvettes and stirring and measurement of contents of the cuvettes are performed in the analysis device.

[0018] Figure 3 is a plan view of an analysis table provided in the analysis device.

[0019] Figure 4 is a diagram for explaining Figure 3 the configuration of the arm shown.

[0020] Figure 5 is a flowchart showing a series of processes of analysis by the analysis device.

[0021] Figure 6 is a drawing showing an example of a main menu and a reagent management screen.

[0022] Figure 7 is a flowchart showing a process of displaying the time of access to the device by the analysis device.

[0023] Figure 8 is a schematic diagram for explaining a process from the end of sampling of the measurement items PT, PLG to the measurement.

[0024] Figure 9 is a drawing showing a modification example of a main menu and a reagent management screen. DETAILED DESCRIPTION

[0025] Hereinafter, the embodiments will be described in detail with reference to the drawings. In addition, the same or corresponding portions in the drawings are denoted by the same reference numerals, and the description thereof will not be repeated.

[0026] [Embodiment 1]

[0027] The automatic analysis device (hereinafter, simply referred to as "analysis device") according to the present embodiment is configured to individually dispense a specimen and a reagent into a reaction vessel through a dispensing nozzle, and to optically measure a reaction state in the reaction vessel. Hereinafter, the dispensing nozzle, the specimen, and the reagent will be referred to as "probe", "sample", respectively. As the sample, for example, blood components and urine can be used. In the present embodiment, as the reaction vessel of the analysis device, for example, a disposable cuvette (for example, the cuvette 100 shown in Figure 3 will be described below. The analysis device 1000 is configured to measure a reaction state in the cuvette 100 by irradiating the cuvette 100 with light, and to measure a reaction state in the cuvette 100 by irradiating the cuvette 100 with light. Figures 1-5 The outline of the analysis device will be described. In addition, the automatic analysis device is, for example, a (general) clinical chemistry analysis device, an electrolyte analysis device, a blood gas analysis device, an immune serum inspection device, a blood inspection device, a blood cell counting device, a blood coagulation analysis device, a urine inspection device, and the like, and is a device having a mechanism for transporting a container of a specimen or the like.

[0028] Figure 1 is a drawing showing a control system of the analysis device 1000. The analysis device 1000 is provided with a control device 500, a reagent refrigeration tank 700, a sample rack 800, a reading device 150, an opening / closing sensor 160, a sample dispensing device 20, an abnormality detection sensor 30, a cuvette supply device 110, a cuvette transport device 120, a reagent dispensing device 10, a stirring device 200, a measurement device 300, and an input / output device 600.

[0029] The control device 500 includes a CPU (Central Processing Unit) 510, a RAM (Random Access Memory) 520, a storage device 530, and an input / output buffer for inputting and outputting various signals. The control device 500 controls the reagent refrigerating box 700, the sample rack 800, the reading device 150, the opening / closing sensor 160, the sample dispensing device 20, the cuvette supply device 110, the cuvette conveying device 120, the reagent dispensing device 10, the stirring device 200, the measuring device 300, and the input / output device 600.

[0030] The CPU 510 expands the control program stored in the storage device 530 in the RAM 520 and executes the control program. The control program is a program in which processes of various processing performed by the control device 500 are described. In the storage device 530, in addition to the control program in which the processes of the processing are described, various information (for example, reagent information, sample information, an analysis schedule, an analysis history record, and the like) used in the various processing is stored. The reagent information is information of reagents stored in the reagent refrigerating box 700. The sample information is information of samples stored in the sample rack 800. The analysis schedule is an order in which analysis is performed. The analysis device 1000 decides the analysis schedule based on analysis items of each sample and the idle state of each port described later to efficiently perform analysis of all samples for which reservation has been made. Thus, the analysis device 1000 can analyze a plurality of samples in parallel. The analysis history record is information including a progress state of analysis and a measurement result, and is updated sequentially as the analysis progresses. The control device 500 performs various processing in the analysis device in accordance with these control programs and various information. Furthermore, as to the processing, it is not limited to execution by software, and can be executed by a dedicated hardware (electronic circuit).

[0031] The reagent refrigerating box 700 accommodates and refrigerates a reagent container in which a reagent for analysis is loaded. An identifier (for example, a bar code, a QR code (registered trademark), a data matrix, and the like) capable of specifying the reagent in the reagent container is attached to the reagent container. In the identifier attached to the reagent container, information (for example, a kind of reagent (analysis item), information indicating whether the reagent is one reagent type or two reagent types, a lot number of the reagent, a use-by date of the reagent, a serial number of the reagent, a shape of the reagent container, a capacity of the reagent container, a number of analyzable times, and the like) related to the reagent container and the reagent in the reagent container is embedded.

[0032] The sample rack 800 is used to house sample containers into which samples that are the analysis targets are loaded. The sample containers are attached with identifiers (e.g., bar codes, QR codes (registered trademark), data matrices, etc.) that can identify the samples in the sample containers. Information (e.g., patient information, IDs of the samples, analysis items, etc.) related to the samples in the sample containers is embedded in the identifiers attached to the sample containers.

[0033] The reading device 150 includes a reading device 150A that reads the identifiers attached to the reagent containers and a reading device 150B that reads the identifiers attached to the sample containers.

[0034] The opening / closing sensor 160 includes an opening / closing sensor 160A that detects the opening / closing of the lid of the reagent refrigeration tank 700 and an opening / closing sensor 160B that detects the opening / closing of the lid of the sample rack 800.

[0035] The sample dispensing device 20 dispenses the sample into the cuvette. The cuvette supply device 110 supplies empty cuvettes to a position (sample dispensing port) at which the sample dispensing device 20 can dispense the sample. The cuvette conveying device 120 conveys the cuvette into which the sample has been dispensed. The reagent dispensing device 10 dispenses the reagent into the cuvette into which the sample has been dispensed. The stirring device 200 stirs the contents of the cuvette under prescribed conditions (e.g., stirring speed and stirring time). The measuring device 300 performs a prescribed measurement on the contents of the cuvette. In the present embodiment, the measuring device 300 has a light source and a light detector, irradiates the light of the light source to the contents of the cuvette, and measures the reaction state in the cuvette based on a change in the amount of light detected by the light detector.

[0036] The abnormality detection sensor 30 is a sensor for detecting various abnormalities of the analysis device 1000, and is provided at each portion of the device. The abnormality detection sensor 30 is, for example, a sensor that monitors the suction state of the first probe 11a used when the reagent is dispensed by the reagent dispensing device 10, a sensor that monitors the suction state of the second probe 21a used when the sample is dispensed by the sample dispensing device 20, or the like, and is used to detect abnormalities related to the suction of the probe or the like.

[0037] In addition, the abnormality detection sensor 30 is, for example, a sensor that monitors the driving device 122 that conveys the cuvette 100 by the cuvette conveying device 120, or the like, and is used to detect abnormalities related to the conveyance of the cuvette 100. Also, the abnormality detection sensor 30 is, for example, a sensor that monitors the liquid level of the reagent in the reagent dispensing device 10, or the like, and is used to detect an abnormality of the reagent in which the liquid level is insufficient. The abnormality detection sensor 30 is able to detect, for example, at least an abnormality of a shortage of cleaning water, a waste liquid tank amount, a reaction container, a reaction container waste amount, a reagent, a conveyance error of the container, and an error related to the presence or absence of a calibration curve.

[0038] Among the abnormalities detected by the abnormality detection sensor 30 are included an abnormality that causes an interrupt process that enables the analysis to continue and an abnormality that causes an emergency stop that cannot continue the analysis. In the present embodiment, the processing in a case where an abnormality that causes an interrupt process that enables the analysis to continue is detected is explained. Further, in the present embodiment, the abnormality detection sensor 30 functions as a structure that detects an interrupt in the processing in the analysis device 1000. In addition, in the present embodiment, the abnormality detection sensor 30 is configured to be able to detect a user’s interrupt operation and a time of the interrupt operation, a kind of abnormality that is a cause of the interrupt, and a time when the abnormality is detected.

[0039] The input / output device 600 includes an input device that receives an input from a user and an output device that performs a predetermined output (for example, display of a reagent management screen, display of an analysis schedule, display of an analysis history, notification of an error, and the like) to the user. The input / output device 600 outputs a signal corresponding to a user’s operation to the control device 500 in a case where the operation is received. The input / output device 600 performs a predetermined display or notification in accordance with a request from the control device 500 in a case where the request is present. The input / output device 600 can employ a device in which an input device and an output device such as a touch panel display are integrated. Further, the input device and the output device can be provided separately. The input device can be, for example, an operation section of various pointing devices (for example, a mouse, a touch panel, and the like), a keyboard, or a portable device (for example, a smartphone, and the like). The manner of output to the user is arbitrary, and the notification can be performed by display on a display device (for example, display of characters or images), by a speaker with sound (including voice), or by causing a predetermined lamp to be lit (including blinking).

[0040] Figure 2 is a diagram showing a structure in which the analysis device 1000 performs transport and disposal of cuvettes and stirring and measurement of contents of the cuvettes.

[0041] The analysis device 1000 is provided with a sample dispensing port P1. The cuvette supply device 110 includes a cuvette housing portion 111 and a supply mechanism 112. The cuvette housing portion 111 is able to house a plurality of cuvettes (for example, up to 1000). The supply mechanism 112 supplies the cuvettes housed in the cuvette housing portion 111 to the sample dispensing port P1. Details of the cuvette housing portion 111 and the supply mechanism 112 will be described in Figure 3 .

[0042] The sample dispensing port P1 is disposed at a position at which the sample dispensing device 20 Figure 1 is able to dispense a sample to a cuvette. When a cuvette is placed at the sample dispensing port P1, the sample dispensing device 20 dispenses a sample to the cuvette.

[0043] The cuvette conveying device 120 includes an arm with a gripper (hereinafter, simply referred to as "arm 121") and a driving device 122. The arm 121 has a gripper configured to be able to hold a cuvette. The arm 121 is configured to releasably hold a cuvette by the gripper. The driving device 122 causes the arm 121 to act to change the position of the gripper. Details of the arm 121 and the driving device 122 will also be described in Figure 3 .

[0044] The analysis device 1000 also has a plurality of ports capable of conveying cuvettes by the cuvette conveying device 120, and specifically, has a stirring port P2, a photometric port P3, and a disposal port P4. The photometric port P3 includes a plurality of scattering ports P3a and a plurality of cuvette ports P3b. A port sensor for detecting the presence or absence of a cuvette is provided at each of the sample dispensing port P1, the stirring port P2, the photometric port P3, and the disposal port P4.

[0045] The stirring port P2 is disposed at a stirring position of the stirring device 200. When a cuvette is placed at the stirring port P2, the stirring device 200 stirs the content of the cuvette under prescribed conditions (e.g., stirring speed and stirring time).

[0046] The scattering ports P3a and the cuvette ports P3b are respectively disposed at measurement positions of the measurement device 300. Hereinafter, the scattering ports P3a and the cuvette ports P3b will be described as "photometric ports P3" respectively, except for cases where it is necessary to distinguish between them.

[0047] The measurement device 300 is configured to perform a prescribed measurement on the content of a cuvette. In the present embodiment, the measurement device 300 has a light source and a light detector, and irradiates the content of a cuvette placed at any one of the photometric ports P3 with light from the light source, and measures the reaction state in the cuvette based on a change in the amount of light detected by the light detector. The measurement device 300 includes a light source and a light detector for the scattering ports P3a, and a light source and a light detector for the cuvette ports P3b. As the light source and the light detector for the scattering ports P3a, a light-emitting diode and a photodiode can be used respectively. The light detector for the scattering ports P3a detects 90° scattered light (i.e., scattered light in a direction orthogonal to the direction of irradiation of light). As the light source and the light detector for the cuvette ports P3b, a halogen lamp and a photodiode can be used respectively. The light detector for the cuvette ports P3b detects the amount of transmitted light.

[0048] The disposal port P4 is used to collect used cuvettes. The disposal port P4 is connected to the cuvette disposal container 400 via a pipe. When a cuvette is dropped into the disposal port P4, the cuvette is guided to the cuvette disposal container 400.

[0049] Figure 3 is a plan view of an analysis table provided in the analysis device 1000. In Figure 3 three axes (X-axis, Y-axis, and Z-axis) orthogonal to each other are shown. Among the X-axis, Y-axis, and Z-axis, the X-axis indicates the width direction of the analysis device, the Y-axis indicates the depth direction of the analysis device, and the Z-axis indicates the vertical direction (i.e., the up-down direction). The direction indicated by the arrow of the Z-axis corresponds to "up", and the opposite direction thereof corresponds to "down (i.e., the direction of gravity)".

[0050] Referring to Figure 2 and Figure 3 The cuvette housing portion 111 houses a plurality of cuvettes 100. The user can replenish the cuvettes 100 into the cuvette housing portion 111 from the insertion port of the cuvette housing portion 111. The material of the cuvette 100 is arbitrary as long as the cuvette 100 can transmit light, and for example, a transparent acrylic material can be used.

[0051] The supply mechanism 112 takes out the cuvettes 100 one by one from the cuvette housing portion 111 and supplies them to the sample dispensing port P1. The conveying method of the supply mechanism 112 to convey the cuvettes 100 is arbitrary, and for example, any one of a slide table method (self-weight method), a conveyor belt method, a roller method, and a sliding method can be used. The supply mechanism 112 receives the detection result of the port sensor of the sample dispensing port P1, and if the sample dispensing port P1 is free, supplies the next cuvette 100 to the sample dispensing port P1. However, the supply mechanism 112 can supply the cuvettes 100 to the sample dispensing port P1 in accordance with the instruction from the control device 500 ( Figure 1 ).

[0052] The arm 21 is a device (sample dispensing device 20 ( Figure 1 ) for dispensing the sample sucked from the sample suction port P21 into the cuvette 100 placed in the sample dispensing port P1. The arm 21 includes a second probe 21a and an arm body 21b. The second probe 21a provided at the front end of the arm body 21b moves in a circular arc-like track L2 on the XY plane by rotation of the arm body 21b around the rotation axis 23a.

[0053] The second probe 21a moves to each of the sample dispensing port P1, the sample suction port P21, the S port P22, and the washing port P23 provided on the track L2 by rotation of the arm body 21b. The S port P22 includes a detergent port P22a, P22b, a buffer port P22c, P22d, P22e, and a plasma-deficient port P22f, P22g, P22h, P22i.

[0054] A movable sample rack 800 ( Figure 1). A plurality of sample containers in which blood components or urine or the like are stored are placed on the sample rack 800. Before the sample is dispensed to the cuvette 100 placed at the sample dispensing port PI, the sample rack 800 is operated so that the sample container of the dispensing target is disposed directly below the sample suction port P21. The CTS mechanism 24 is disposed in the vicinity of the sample suction port P21. In the case where the sample container of the dispensing target is attached with a cap, the CTS mechanism 24 perforates the cap with a perforator.

[0055] The arm 11 is a device (reagent dispensing device 10) for dispensing reagents sucked from the suction ports PI 1, PI 2 to the cuvette 100 placed at the measurement port P3 as a target. Figure 1 The arm 11 includes a first probe 11a and an arm body 1 Ib. The first probe 11a disposed at the front end of the arm body 1 Ib is moved in the XY plane in a manner of tracing a circular arc-shaped track LI by rotation of the arm body 1 Ib around the rotation axis 13a.

[0056] A reagent tray 710 on which a plurality of reagent containers A (or a plurality of washing agent containers) are placed is disposed below the suction ports PI 1, PI 2. The reagent tray 710 is disposed in a reagent refrigeration box 700. The plurality of reagent containers A hold mutually different reagents, and the plurality of washing agent containers hold mutually different washing agents. The reagent tray 710 is a turntable in a disc shape, and by driving the turntable, a desired reagent container A (or washing agent container) is disposed directly below the suction ports PI 1, PI 2. The first probe 11a is used to suck a reagent (or a cleaning liquid) in the reagent container A (or washing agent container) disposed directly below the suction ports PI 1, PI 2.

[0057] The first probe 11a is moved to each port disposed on the track LI, the stirring port P2, each scattering port P3a, each cuvette port P3b, the suction ports PI 1, PI 2, and the recovery port PI 3 by rotation of the arm body 1 Ib. Further, in order to avoid contamination between reagents, the first probe 11a can also be composed of two probes. In addition, the reagent tray 710 can have an outer peripheral tray and an inner peripheral tray. The two probes suck a reagent (or a cleaning liquid) on the outer peripheral tray and a reagent (or a cleaning liquid) on the inner peripheral tray from the suction ports PI 1, PI 2. The recovery port PI 3 is a port for recovering a used cleaning liquid, and although not particularly illustrated, includes a sump for storing water ejected from the first probe 11a and cleaning the outer surface of the probe front end, and a waste portion for discarding the liquid.

[0058] The arm 121 includes a gripper 121a and an arm body 121b. The gripper 121a is configured to be able to hold the cuvette 100. The manner in which the gripper 121a holds the cuvette 100 is arbitrary, and the gripper 121a can be either a mechanical gripper or a magnetic gripper, or a vacuum gripper. The gripper 121a provided at the front end of the arm body 121b is able to move in a circular arc-like track L1 on the XY plane by rotation of the arm body 121b about the rotation axis 122a.

[0059] As described above, the rotation centers of the arms 11 and 121 are the same. The sample dispensing port P1, the stirring port P2, the plurality of light measurement ports P3 (the plurality of scattering ports P3a and the plurality of colorimetric ports P3b), the waste port P4, the suction ports P11 and P12, and the recovery port P13 are provided on the track L1. The arm 121 is able to move the gripper 121a to the sample dispensing port P1, the stirring port P2, each light measurement port P3, and the waste port P4, and the arm 11 is able to move the first probe 11a to the suction ports P11 and P12, the recovery port P13, the stirring port P2, and each light measurement port P3.

[0060] Figure 4 is a view for explaining Figure 3 the configuration of the arms 11 and 121. Figure 4 The X axis, the Y axis, and the Z axis in Figure 3 correspond to the X axis, the Y axis, and the Z axis in

[0061] Referring to Figure 3 and Figure 4 , the arms 11 and 121 are arranged in the up-down direction with a gap. In the present embodiment, the arm 11 is arranged at a higher position than the arm 121. The first probe 11a is connected to the front end portion E1 of the arm body 11b, and the rotation axis 13a is connected to the base end portion E2 of the arm body 11b. The first probe 11a has an opening portion OP at the front end. The elevating actuator of the drive device moves the arm 11 and the rotation axis 13a integrally in the up-down direction, whereby the arm 11 (and further the first probe 11a) is displaced up and down. For example, the first probe 11a is lowered to approach the cuvette 100B when dispensing a reagent to the cuvette 100B placed at the colorimetric port P3b, and the first probe 11a is raised to move away from the cuvette 100B when the reagent dispensing is completed.

[0062] The jig 121a is connected to the front end portion E3 of the arm body 121b, and the rotation shaft 122a is connected to the base end portion E4 of the arm body 121b. The base end portion E4 of the arm body 121b is held on the rotation shaft 122a in a manner so as to be displaceable in the up-and-down direction. The lifting actuator of the drive device displaces the arm 121 in the up-and-down direction, whereby the arm 121 (and further the jig 121a) is displaced up and down. For example, the jig 121a is lowered to grip the cuvette 100A when the cuvette 100A is transported to the scattering port P3a, and is raised in the state of gripping the cuvette 100A to leave the scattering port P3a. Thereafter, the arm 121 is rotationally driven by the drive device, and after the jig 121a reaches the port (more specifically, a certain port on the track LI) of the transport destination, the jig 121a is lowered again to place the cuvette 100A at the port. After the cuvette 100A is placed at the port, the jig 121a releases the cuvette 100A (i.e., the jig is released) and is raised again.

[0063] Next, the flow of analysis by the analysis device 1000 will be described. The analysis device 1000 performs analysis of a plurality of samples in accordance with an analysis schedule ( Figure 1 ). Specifically, the analysis device 1000 performs preparation for measurement (aspiration at the port P11 ( Figure 3 ) or dispensing at the sample aspiration port P21 ( Figure 3 )) of a certain sample while performing measurement (optical measurement at the measurement port P3 ( Figure 3 )) of another sample. The analysis schedule is determined by the analysis device 1000 on the basis of sample information (e.g., analysis items of each sample) and the idle state of each port, so that analysis of all the samples that have been reserved is efficiently performed. The analysis schedule includes, in the analysis schedule, the timing of dispensing and the timing of measurement, information of the sample as a dispensing target, information of the reagent as a dispensing target, and the number of the measurement port P3 ( Figure 3 ) at which measurement is performed. The analysis schedule is stored in the storage device 530 ( Figure 1 ), and the analysis schedule is managed for each sample ID (each sample container).

[0064] When analysis is started, the cuvette 100 ( Figure 3 ) used in the analysis is given an ID (ID of the cuvette). When analysis is performed, an analysis history record ( Figure 1 ) including the history of the analysis so far is stored in the storage device 530 Figure 1 ). The analysis history record is updated sequentially as the analysis progresses. The analysis history record includes, in the analysis history record, the movement path of the cuvette 100 (containing the current position), the sample and the reagent dispensed into the cuvette 100, and the measurement port P3 ( Figure 3) and the measurement result. The analysis history is managed by each cuvette ID (100 cuvettes). The user can confirm whether the analysis is performed according to the analysis schedule (or whether there is progress) by referring to the analysis history.

[0065] Figure 5 is a flowchart showing a series of flows of the analysis by the analysis device 1000. Figure 5 The processing shown is processing performed by the control device 500, and is realized by the CPU 510 executing the control program stored in the storage device 530.

[0066] Referring to Figure 1 , Figure 3 and Figure 5 , first, the control device 500 supplies the cuvette 100 to the sample dispensing port Pl (step S510). Specifically, the supply mechanism 112 takes out the cuvette 100 from the cuvette housing portion 111 and supplies it to the sample dispensing port Pl. The supply mechanism 112 supplies the next cuvette 100 to the sample dispensing port Pl if it learns from the output of the port sensor of the sample dispensing port Pl that the sample dispensing port Pl is free.

[0067] Next, the control device 500 dispenses a sample into the cuvette 100 and stirs the contents of the cuvette 100 (step S520). Specifically, the control device 500 controls the movable sample rack 800 while referring to the analysis schedule, thereby arranging a prescribed sample (more specifically, a sample designated by the analysis schedule) directly below the sample suction port P21. Next, the control device 500 controls the drive device to move the second probe 21a to the sample suction port P21 and to cause the second probe 21a to suck the sample. Next, the control device 500 controls the drive device to move the second probe 21a to the sample dispensing port Pl and to dispense the sample from the second probe 21a into the cuvette 100 (more specifically, the cuvette 100 supplied to the sample dispensing port Pl in step S510). After the dispensing, the second probe 21a is cleaned.

[0068] Next, the control device 500 transports the cuvette 100 to the light measurement port P3 (step S530). Specifically, the control device 500 controls the drive device to move the arm 121, thereby transporting the cuvette 100 from the sample dispensing port Pl to the light measurement port P3.

[0069] Next, the control device 500 transports the cuvette 100 to the stirring port P2 (step S540). Specifically, the control device 500 controls the drive device to move the arm 121, thereby transporting the cuvette 100 from the light measurement port P3 to the stirring port P2. However, in the case where the analysis item is a coagulation item, the step S540 and the step S560 to be described later are omitted. In this case, in the step S550 to be described later, the control device 500 dispenses a reagent to the cuvette 100 located at the light measurement port P3, and does not perform stirring after the dispensing. The contents of the cuvette 100 are mixed by the head of the reagent jet in the step S550.

[0070] In the step S550, the control device 500 dispenses a reagent to the cuvette 100 in which the sample is loaded, and stirs the contents of the cuvette 100. Specifically, the control device 500 drives the turntable of the reagent refrigerating box 700 while referring to the analysis schedule, thereby arranging a prescribed reagent (more specifically, a reagent designated by the analysis schedule) directly below the suction port Pll. Next, the control device 500 controls the drive device to move the first probe 11a to the suction port Pll, and causes the first probe 11a to suck the reagent. Next, the control device 500 controls the drive device to move the first probe 11a to the stirring port P2, and dispenses the reagent from the first probe 11a to the cuvette 100. After the dispensing, the contents of the cuvette 100 are stirred by the stirring device 200. In addition, after the dispensing, the first probe 11a is cleaned.

[0071] In the case where the analysis item is a cuvette analysis item of two reagent types, the control device 500 repeatedly performs the processes of the steps S530 to S550 described above, to perform dispensing of the first reagent and the second reagent. After the dispensing of all the reagents is completed, the control device 500 transports the cuvette 100 to the light measurement port P3 (step S560).

[0072] Next, the control device 500 performs the measurement to be described later by controlling the measurement device 300 (step S570).

[0073] For example, in the case where the sample is plasma and the analysis item is a coagulation item, the coagulation time of the sample is measured at the scattering port P3a. As the coagulation progresses, the intensity of the scattered light increases, and when the coagulation reaction ends, the intensity of the scattered light hardly changes any more, so the coagulation time can be found from the intensity of the scattered light.

[0074] In the case where the sample is blood plasma and the analysis item is a colorimetric item, the concentration and activity value of the sample are measured at the colorimetric port P3b. The control device 500 dispenses the first reagent into the cuvette 100 after a prescribed time has elapsed from dispensing the sample into the cuvette 100, and then dispenses the second reagent (more specifically, a reagent different from the first reagent) into the cuvette 100 after a prescribed time has elapsed from dispensing the first reagent. By dispensing the second reagent into the cuvette 100, the sample starts to react with the reagent, and the absorbance of the contents of the cuvette 100 changes. The concentration and activity value of the sample can be calculated from such a change in absorbance. In such a measurement, the first probe 11a is cleaned after dispensing of each of the first and second reagents is performed.

[0075] In the case where the sample is urine, for example, the change in absorbance due to the reaction of the sample with the reagent is measured optically at the colorimetric port P3b.

[0076] When the above measurement is completed, the control device 500 disposes of the cuvette 100 (step S580). Specifically, the control device 500 controls the drive device to move the arm 121, thereby transporting the cuvette 100 from the measurement port P3 to the disposal port P4, and releases the gripper of the arm 121 to drop the cuvette 100 into the disposal port P4. When the cuvette 100 (i.e., the used reaction container) is dropped into the disposal port P4, it is collected into the cuvette disposal container 400 Figure 2 ).

[0077] After step S580, the control device 500 starts the analysis of the next sample designated by the analysis schedule, and thus the processing is transferred to step S510.

[0078] Thus, the analysis device 1000 dispenses the sample and the reagent into the cuvette 100, respectively, and optically measures the reaction state in the cuvette 100. The analysis item differs for each sample, and the reagent used differs for each analysis item. Thus, if the combination of the sample and the reagent dispensed into the cuvette 100 is incorrect, the correct analysis cannot be performed. The analysis device 1000 manages the information of the reagents in the reagent refrigerator 700 Figure 1 ) by reading the identifiers attached to the reagent containers. In addition, the analysis device 1000 manages the samples in the sample rack 800 Figure 1information of the sample and the reagent, the analysis device 1000 configures the sample designated by the analysis schedule right below the sample suction port P21 and configures the reagent designated by the analysis schedule right below the suction port P11. In order to obtain a correct analysis result, it is necessary to correctly perform dispensing of the sample and the reagent, and for this purpose, it is necessary to update the reagent information and the sample information to the latest state at the start of analysis.

[0079] In the analysis device 1000, when an abnormality is detected by the abnormality detection sensor 30, depending on the kind of the detected abnormality, there are a case where analysis can be continued and is set as an interruption process, and a case where analysis cannot be continued and is set as an emergency stop. In the case of the emergency stop, the analysis device 1000 needs to discard the sample dispensed until then without analyzing it. On the other hand, in the case of the interruption process, the analysis device 1000 can continue analysis of the sample dispensed until then and obtain an analysis result of the sample.

[0080] However, in the case of the interruption process of the analysis device 1000, the user cannot access a prescribed area (for example, the lid of the reagent refrigeration tank 700 or the reagent dispensing device 10, the arm 121 for transporting the cuvette 100, and the like) until analysis of the sample dispensed until then is completed. In the case where an abnormality is detected, the user needs to access the prescribed area of the analysis device 1000 to eliminate the cause of the abnormality. For example, in the case where an abnormality of a liquid residual amount shortage of the reagent is detected in the reagent dispensing device 10, the user needs to open the lid of the reagent dispensing device 10 to replace the reagent container of the liquid residual amount shortage with a new reagent container after confirming that the operation of the arm 11 of the first probe 11a is stopped.

[0081] In addition, the time from when the interruption process occurs until the user can access the prescribed area of the analysis device differs depending on the number of samples dispensed until then, and in the case of the existing device, the user cannot easily know the time. The case where the interruption process is caused by an abnormality such as a liquid residual amount shortage of the reagent is a case that occurs on a daily basis, and every time the user needs to interrupt the work and wait until the prescribed area of the device can be accessed, the work efficiency is significantly reduced.

[0082] Therefore, the analysis device 1000 according to the present embodiment displays the time at which the user can access the prescribed area of the analysis device 1000 after the interruption process has occurred. By knowing the time at which the prescribed area of the analysis device 1000 can be accessed (hereinafter, also simply referred to as the device accessible time), the user can perform other work before the device accessible time without waiting in front of the analysis device 1000, and thus the work efficiency is improved.

[0083] Specifically, an example of displaying the accessible device time in the main menu and reagent management screen is illustrated using a drawing. Figure 6 is a drawing illustrating an example of the main menu and reagent management screen. The main menu Gl includes a button for instructing start of analysis, a button for instructing suspension of analysis, and a button that is lit in a case where an error has occurred in the analysis device 1000, and the like. The reagent management screen G2 is a screen for showing the user information of reagents in the reagent cooling box 700. The main menu Gl and the reagent management screen G2 are displayed on the input / output device 600.

[0084] The current time Tl is always displayed at the right end of the main menu Gl. Also, in a case where an abnormality that causes an interruption process is detected, the accessible device time T2 is displayed in the main menu Gl at the right side or the lower side of the current time Tl. The user compares the accessible device time T2 with the current time Tl to confirm how many minutes are left until the prescribed area of the analysis device 1000 can be accessed, and thus can perform other work. In a case where the user is notified of the occurrence of an abnormality, the user can confirm the time until the prescribed area of the analysis device 1000 can be accessed, and thus can perform other work. Figure 6 In the example shown, the accessible device time T2 is 13:58 and the current time Tl is 13:55, and thus it is known that the prescribed area of the analysis device 1000 can be accessed in 3 minutes.

[0085] The arrangement of the reagent containers A in the reagent cooling box 700 and the information embedded in the identifiers attached to each reagent container A are displayed in the reagent management screen G2. The image G21 simulating the reagent tray 710, the image G22 simulating the holders Ha of the reagent tray 710, and the numbers N of the holders Ha are displayed in the reagent management screen G2. The image in the image G22 in which no character is displayed shows a case where no reagent container A is arranged on the holder Ha. The image in the image G22 in which a character is displayed shows a case where a reagent container A is arranged on the holder Ha. For example, the image G22 of the number N of 1 shows the following content: the reagent container A arranged on the holder Ha of No. 1 contains a reagent of "PT-n", and the analysis of the item of "PT-n" can be performed 42 times using the reagent.

[0086] The images G23, G24 simulating arrows are buttons for causing the reagent tray 710 to rotate. When the user presses the image G23 once, the reagent tray 710 rotates by an amount of one frame (72 degrees in the example shown) in the direction of the arrow. When the user presses the image G24 once, the reagent tray 710 rotates by an amount of two frames (144 degrees in the example shown) in the direction of the arrow. The user can operate the buttons on the reagent management screen G2 to move the holder Ha in which the user wants to arrange the reagent container A to a position at which the lid is open in a case where the user has only opened the lid and arranged the reagent container A on the reagent tray 710. Figure 6 Figure 6 The images G23, G24 simulating arrows are buttons for causing the reagent tray 710 to rotate. When the user presses the image G23 once, the reagent tray 710 rotates by an amount of one frame (72 degrees in the example shown) in the direction of the arrow. When the user presses the image G24 once, the reagent tray 710 rotates by an amount of two frames (144 degrees in the example shown) in the direction of the arrow. The user can operate the buttons on the reagent management screen G2 to move the holder Ha in which the user wants to arrange the reagent container A to a position at which the lid is open in a case where the user has only opened the lid and arranged the reagent container A on the reagent tray 710. ​

[0087] In the detail information column G25, detailed information about the reagent container A selected on the reagent management screen is displayed. In the detail information column G25, for example, the reagent name (the kind of reagent, the analysis item), information indicating whether the reagent is one reagent class or two reagent classes, the lot number of the reagent, the expiration date of the reagent, the serial number of the reagent, the shape of the reagent container (the type of the reagent container), the capacity of the reagent container, the number of analyzable times, and the like are displayed. Among these pieces of information, the information embedded in the identifier attached to the reagent container A and the information calculated by the control device 500 based on the information embedded in the identifier attached to the reagent container A are included.

[0088] Next, the processing at the accessible device time T2 displayed in the main menu Gl in the case where the analysis device 1000 detects an abnormality that causes the interrupt processing will be described using a flowchart. Figure 7 is a flowchart illustrating the processing of displaying the accessible device time T2 in the analysis device 1000. First, the control device 500 judges whether an abnormality that causes the interrupt processing is detected based on the detection signal from the sensor provided to the analysis device 1000 (step S71). In the case where it is judged that an abnormality that causes the interrupt processing is not detected (NO in step S71), the control device 500 returns the processing to step S71 and continues to monitor whether an abnormality that causes the interrupt processing is detected in the analysis device 1000.

[0089] On the other hand, in the case where it is judged that an abnormality that causes the interrupt processing is detected (YES in step S71), the control device 500 calculates the time at which the prescribed area of the analysis device 1000 can be accessed (the accessible device time T2) based on the conveyance state of the container at the time of detection of the interrupt (step S72). For example, the predicted time at which the reagent whose liquid level is insufficient can be replaced is calculated from the number of remaining items of the specimen in the sampling at the time of the interrupt processing, and the current time is added to the predicted time, whereby the time at which the prescribed area of the analysis device 1000 can be accessed can be calculated.

[0090] The method of calculating the predicted time will be described in more detail. The predicted time can be calculated by (the number of remaining items of the specimen in the sampling) x 18 seconds + (the time from the end of sampling of the final item to the measurement). The time from the end of sampling of the final item to the measurement differs depending on the measurement item of the specimen, and will be described taking the prothrombin time (PT) and PLG, which are measurement items of the coagulation function and the fibrinolysis function of the specimen, as examples. Figure 8 is a schematic diagram for explaining the processing from the end of sampling to the measurement of the measurement items PT and PLG.

[0091] In Figure 8(a) shows the process from the completion of sampling to the measurement of measurement item PT. Measurement item PT can be measured by heating the plasma sampled into the container for 45 seconds and then heating it for 171 seconds after dispensing the reagent. The maximum measurement time for measurement item PT is 200 seconds.

[0092] exist Figure 8 (b) shows the process from sampling to measurement for the PLG measurement item. For the PLG measurement item, the measurement can be performed by heating the plasma sampled into the container for 45 seconds, then dispensing the first reagent and heating it for 171 seconds, followed by dispensing the second reagent. The PLG measurement takes a maximum of 300 seconds.

[0093] like Figure 8 (a) and Figure 8 As shown in (b), the time from the end of sampling to the measurement requires a total of 216 seconds, which is the total of 45 seconds of heating time until the reagent is dispensed and 171 seconds of heating time until the measurement.

[0094] Therefore, when the number of remaining items of the specimen being sampled is set to three, for example, the predicted time can be calculated as (the number of remaining items of the specimen being sampled = 3) × 18 seconds + (the time from the end of sampling of the final item to the measurement = 216 seconds) = 270 seconds. Furthermore, the accessible device time T2 can be calculated by (current time) + (predicted time). For example, when the current time is 15:55:00, the predicted time of 4 minutes and 30 seconds (= 270 seconds) is added to calculate the accessible device time T2 as 15:59:30. In addition, when the calculation is performed in a manner that rounds up the seconds, the accessible device time T2 can also be calculated as 16:00. In addition, the control device 500 can also calculate the accessible device time T2 based on a predetermined waiting time (e.g., 5 minutes) instead of the transport status of the container when the interruption is detected.

[0095] Return to Figure 7 The control device 500 displays the time (accessible device time T2) at which the specified area of ​​the analysis device 1000 can be accessed, calculated in step S72, at a specified position on the main menu G1 (step S73). Figure 6 In the main menu G1, the position to the right or below the current time T1 is the specified position for displaying the accessible device time T2. However, the position is not limited to this position, and the user can set it to any position on the screen displayed by the input / output device 600. In addition, the control device 500 can also display the time until the accessible device time T2 at a specified position on the main menu G1 instead of the accessible device time T2.

[0096] The control device 500 determines whether the current time has passed 30 seconds before the accessible device time T2 (step S74). If the current time has not passed 30 seconds before the accessible device time T2 ("No" in step S74), the control device 500 returns the process to step S73 and continues to display the accessible device time T2. On the other hand, if the current time has passed 30 seconds before the accessible device time T2 ("Yes" in step S74), the control device 500 performs a preview display indicating that the specified area of ​​the analysis device 1000 will soon be accessible (step S75). For example, the control device 500 displays a countdown of the remaining time until the specified area becomes accessible in the main menu G1 as a preview display. Furthermore, the control device 500 may continue to display the accessible device time T2 even while the preview display is being performed. While the preview display is performed at 30 seconds before the accessible device time T2, this is not limited to this and the preview display time can be freely set. Furthermore, the control device 500 can also be set so as not to display the preview when the preview display is unnecessary.

[0097] Next, the control device 500 determines whether the current moment has passed the accessible device time T2 (step S76). If the current moment has not passed the accessible device time T2 ("No" in step S76), the control device 500 returns the process to step S75 and continues the preview display. On the other hand, if the current moment has passed the accessible device time T2 ("Yes" in step S76), the control device 500 displays that the specified area of ​​the analysis device 1000 can be accessed (step S77). The control device 500 displays the display that the specified area can be accessed in the main menu G1, for example. In addition, the control device 500 can also be set to not display the display that the specified area can be accessed when it is not necessary.

[0098] [Modification]

[0099] In the above embodiment, if Figure 6 As shown, the accessible device time T2 is displayed to the right or below the current time T1 of the main menu G1. However, the present invention is not limited thereto, and the control device 500 may also display the accessible device time T2 as a pop-up screen on the screen displayed by the input / output device 600. Figure 9 : is a diagram showing a modified example of the main menu and reagent management screen. Figure 9In the above-described embodiment, the accessable device time T2 is displayed in the screen displayed by the input / output device 600, but a sound output section such as a speaker can be provided in the analysis device 1000, and the accessable device time T2 can be notified to the user from the sound output section by sound.

[0100] Figure 7 The advance display displayed in step S75 and the display of the accessable prescribed area displayed in step S77 can also be displayed in the pop-up screen Pa. In addition, in a case where the analysis device 1000 can be connected to the terminal (for example, a smartphone) of the user by wireless communication or the like, the analysis device 1000 can transmit the accessable device time T2, the advance display, the display of the accessable prescribed area, and the like to the terminal of the user.

[0101] In the above-described embodiment, the accessable device time T2 is displayed in the screen displayed by the input / output device 600, but a sound output section such as a speaker can be provided in the analysis device 1000, and the accessable device time T2 can be notified to the user from the sound output section by sound.

[0102] In the above-described embodiment, the processing in a case where the abnormality detection sensor 30 detects the abnormality of the analysis device 1000 and the interrupt processing is performed is described, but the same processing can be performed in a case where the interrupt processing is performed due to the user pressing the interrupt button. In addition, the interrupt operation of the user pressing the interrupt button can be detected by the abnormality detection sensor 30, and the interrupt processing described in the above-described embodiment can be performed.

[0103] [Mode]

[0104] As understood by those skilled in the art, the above-described exemplified embodiment is a specific example of the following mode.

[0105] (First) An automatic analysis device according to one embodiment is an automatic analysis device for sequentially performing analysis on a plurality of samples, and includes: a conveyance section that conveys a container for housing a sample; a measurement section that sequentially measures the sample conveyed by the conveyance section; a control section that controls the conveyance section so that the container is conveyed to the measurement section in a prescribed order; and a notification section that notifies of a conveyance state of the container controlled by the control section, wherein in a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify of a time at which a user can access a prescribed area of the automatic analysis device.

[0106] The automatic analysis device according to the first aspect, in a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify the user of a time at which the user can access the prescribed area of the automatic analysis device, and thus the user does not reduce work efficiency by effectively using time until the time at which the user can access the prescribed area.

[0107] The automatic analysis device according to the second aspect, the user can easily recognize the time at which the user can access the prescribed area displayed in the display section.

[0108] The automatic analysis device according to the second aspect, the user can easily recognize the time at which the user can access the prescribed area displayed in the display section.

[0109] The automatic analysis device according to the third aspect, the user can easily recognize the time until the user can access the prescribed area displayed in the display section.

[0110] The automatic analysis device according to the third aspect, the user can easily recognize the time until the user can access the prescribed area displayed in the display section.

[0111] The automatic analysis device according to the fourth aspect, the user can easily recognize the remaining time until the user can access the prescribed area displayed in the display section.

[0112] The automatic analysis device according to the fourth aspect, the user can easily recognize the remaining time until the user can access the prescribed area displayed in the display section.

[0113] The automatic analysis device according to the fifth aspect, even a user who cannot watch the display section can easily recognize the time at which the user can access the prescribed area.

[0114] The automatic analysis device according to the fifth aspect, even a user who cannot watch the display section can easily recognize the time at which the user can access the prescribed area.

[0115] The automatic analysis device according to the sixth aspect, the user can easily recognize the time at which the user can access the prescribed area based on the time calculated by the time calculation section.

[0116] The automatic analysis device according to the sixth aspect, calculates the timing at which the prescribed area can be accessed based on the transport state of the container at the time of detection of the interruption, and thus can correctly calculate the timing at which the prescribed area can be accessed.

[0117] (Seventh aspect) In the automatic analysis device according to the sixth aspect, the detection unit can detect at least one of: an interruption operation by a user and a timing of the interruption operation; and a type of an abnormality that is a cause of the interruption and a timing of detection of the abnormality.

[0118] The automatic analysis device according to the seventh aspect, the detection unit detects an interruption operation by a user and a timing of the interruption operation, a type of an abnormality that is a cause of the interruption and a timing of detection of the abnormality, and thus can more correctly calculate the timing at which the prescribed area can be accessed.

[0119] (Eighth aspect) In the automatic analysis device according to the seventh aspect, the detection unit can detect at least one of: a shortage of cleaning water, a waste liquid tank level, a shortage of a reaction container, a reaction container waste level, a shortage of a reagent, a transport error of a container, and an error related to the presence or absence of a calibration curve.

[0120] The automatic analysis device according to the eighth aspect, the detection unit detects at least one of: a shortage of cleaning water, a waste liquid tank level, a shortage of a reaction container, a reaction container waste level, a shortage of a reagent, a transport error of a container, and an error related to the presence or absence of a calibration curve, and thus can detect an abnormality of a process interruption in the automatic analysis device.

[0121] The embodiments disclosed this time are to be considered as illustrative and not restrictive in all points. The scope of the application is not shown by the above description, but by the claims below, and it is intended to include all modifications within the meaning and scope of the claims, equivalent to the claims.

Claims

1. An automatic analysis device for sequentially analyzing a plurality of samples, the automatic analysis device comprising: a conveyance section that conveys a container for housing the sample; a measurement section that sequentially measures the sample conveyed by the conveyance section; a control section that controls the conveyance section so as to convey the container to the measurement section in a prescribed order; and a notification section that notifies of a conveyance state of the container controlled by the control section, wherein, in a case where processing in the automatic analysis device is interrupted, the control section causes the notification section to notify of a timing at which a prescribed area of the automatic analysis device is accessible by a user, wherein the control section includes: a detection section that detects interruption of processing in the automatic analysis device; and a time calculation section that calculates the timing at which the prescribed area is accessible based on the conveyance state of the container at the time of detection of interruption by the detection section.

2. The automatic analysis device according to claim 1, wherein the notification section is a display section that displays the conveyance state of the container to the user, and the display section displays the timing at which the prescribed area is accessible to the user.

3. The automatic analysis device according to claim 2, wherein the display section displays time until the timing at which the prescribed area is accessible to the user instead of displaying the timing at which the prescribed area is accessible.

4. The automatic analysis device according to claim 2 or 3, wherein the display section displays time until the timing at which the prescribed area is accessible to the user in a display mode in which the time is displayed in a countdown manner.

5. The automatic analysis device according to claim 2 or 3, wherein the notification section further includes a sound output section that outputs the conveyance state of the container by sound, and the sound output section notifies of the timing at which the prescribed area is accessible to the user by sound. wherein 6. The automatic analysis device according to claim 1, wherein the control section includes: a storage section that stores the timing calculated by the time calculation section, and the notification section notifies of the timing at which the prescribed area is accessible to the user based on the timing stored in the storage section.

7. The automatic analysis device according to claim 6, wherein the detection section is capable of detecting at least one of: an interruption operation by the user and a timing of the interruption operation; and a kind of an abnormality that is a cause of interruption and a timing at which the abnormality is detected.

8. The automatic analysis device according to claim 7, wherein the detection section is capable of detecting at least one of: a shortage of cleaning water, a waste liquid tank amount, a shortage of a reaction container, a reaction container waste amount, a shortage of a reagent, a conveyance error of the container, and an error related to presence or absence of a calibration curve. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

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