Mixing device and sample analyzer
By designing a mixing device including a mounting frame, a lifting mechanism and a mixing mechanism, the problems of low artificial mixing efficiency of blood samples and insufficient positioning accuracy of reaction vessels in the prior art are solved, and efficient mixing and accurate analysis are achieved.
Patent Information
- Application Number
- CN202111666208.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-12-31
- Publication Date
- 2025-04-01
- Estimated Expiration
- 2041-12-31
AI Technical Summary
In the prior art, blood samples need to be mixed manually before measuring in the analyzer, resulting in limited batch measurement of samples and high manual operation burden. At the same time, the positioning accuracy during insertion and removal of the reaction container is affected, which can easily lead to failure of grabbing or insertion.
A mixing device is designed, including a mounting frame, a lifting mechanism and a mixing mechanism. The mixing mechanism realizes the swing and lifting of the reaction vessel through the drive assembly and the swing frame. Combined with the driving of the transverse assembly, the mixing effect of the sample is improved and the noise during mixing is reduced.
It realizes efficient mixing of blood samples, improves the accuracy of sample analysis, reduces manual operation, enhances the positioning accuracy and reliability of the reaction vessel, and reduces noise during mixing.
Smart Images

Figure CN114295461B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of sample analysis, and in particular to a mixing device and a sample analyzer using the mixing device. Background Art
[0002] Blood samples need to be fully mixed before measurement, otherwise the measurement results will have a large deviation. At present, when the analyzer measures peripheral blood samples, it is usually necessary to manually mix the samples by flicking them with your fingers before putting them into the analyzer for testing. However, this mixing method greatly limits the number of sample batch measurements and increases the burden of manual operation, which is extremely inconvenient.
[0003] In the related art, an abutment portion is provided in the cup holder for placing a reaction cup or a test tube, so that after the reaction cup or the test tube is inserted into the cup holder, the abutment portion can make the axis of the reaction cup or the test tube have a fixed angle α or eccentricity d with the axis of the cup holder. Such a setting causes the positioning accuracy to be subject to lateral pressure when the test tube is inserted and taken out, affecting the positioning accuracy and reliability of the cup, and more likely to cause the reaction cup to fail to grasp or insert and fall. At the same time, the angle between the reaction cup and the axis of the cup holder cannot be set too large. If it is set too large, the test tube cannot be inserted into the cup holder, and it is easier to drop the test tube. However, if the angle is set too small, the test tube is more difficult to move and mix in the horizontal plane, and the reaction cup holder is a rigid structure, so the noise is relatively large during mixing. Summary of the invention
[0004] The main purpose of the present invention is to provide a mixing device and a sample analyzer, aiming to provide a mixing device with good mixing effect, which is convenient for placing reaction containers, avoids the positioning accuracy of the reaction containers being subjected to lateral pressure when they are inserted and taken out, and affects the positioning accuracy and reliability of the reaction containers, and reduces the noise during mixing.
[0005] To achieve the above object, the present invention provides a mixing device, which comprises:
[0006] A mounting frame, wherein the mounting frame is provided with a transverse movement assembly;
[0007] A lifting mechanism, the lifting mechanism comprising a base plate and a lifting assembly disposed on the base plate, the base plate being movably disposed on the mounting frame and connected to the transverse movement assembly; and
[0008] A mixing mechanism, the mixing mechanism comprises a base, a driving assembly and a mixing assembly, the base is movably arranged on the base plate and connected to the lifting assembly, the driving assembly is arranged on the base, the mixing assembly comprises a swing frame and a container seat, the swing frame is movably connected to the output shaft of the driving assembly, the container seat is rotatably connected to the swing frame, the container seat is provided with a containing cavity, and the containing cavity is used to carry a reaction container;
[0009] Among them, the driving component drives the swing frame to rotate so that the container seat swings relative to the swing frame, the lifting component drives the base to rise and fall along a first direction, and the transverse movement component drives the substrate to move transversely along a second direction, and the first direction and the second direction are set at an angle.
[0010] In one embodiment, the base is provided with a mounting hole, the driving assembly includes a driving member and a crankshaft, the crankshaft includes a main shaft and an eccentric shaft, one end of the main shaft is rotatably inserted into the mounting hole and connected to the eccentric shaft, the axis of the eccentric shaft is parallel to and does not overlap with the axis of the crankshaft, the eccentric shaft is movably connected to the swing frame, the driving member includes a rotating motor, a driven wheel and a transmission belt, the rotating motor is provided on the base, the output shaft of the rotating motor is provided with a driving wheel, the driven wheel is sleeved on the main shaft, and the transmission belt is sleeved on the driving wheel and the driven wheel;
[0011] Wherein, the rotating motor drives the driving wheel to rotate, so that the transmission belt drives the driven wheel and the crankshaft to rotate.
[0012] In one embodiment, the swing frame comprises:
[0013] A rotating seat, wherein the rotating seat is provided with a connecting hole, and an end of the eccentric shaft away from the main shaft is rotatably penetrated through the connecting hole through a bearing member; and
[0014] The support frame is arranged on the rotating seat, the support frame is provided with a swinging groove, and the container seat is swingably arranged in the swinging groove.
[0015] In one embodiment, the support frame comprises:
[0016] a base, the base being disposed on the rotating base; and
[0017] Two support arms, the two support arms are arranged at intervals on a side of the base facing away from the rotating base, the two support arms are arranged opposite to each other, and cooperate with the base to form the swing groove and two through openings connected to the swing groove, and each support arm is provided with an axial hole;
[0018] The outer wall of the container seat is provided with a rotating shaft corresponding to each of the shaft holes, and the rotating shaft is rotatably penetrated through the shaft hole.
[0019] In one embodiment, the swing frame further comprises an anti-collision rod, which is disposed on the rotating seat and corresponds to the through opening;
[0020] Wherein, when the container seat swings around the rotating shaft, one end of the container seat away from the rotating shaft extends out of the through opening and abuts against the anti-collision rod in a limiting manner.
[0021] In one embodiment, the swing frame further comprises an elastic member, one end of the elastic member is connected to the bottom of the container seat, and the other end of the elastic member is connected to the base or the anti-collision rod.
[0022] In one embodiment, the anti-collision rods include two, the two anti-collision rods are respectively arranged on opposite sides of the base and are respectively arranged corresponding to the two through openings, the elastic members include two, one ends of the two elastic members are connected to the bottom of the container seat, and the other ends of the two elastic members are respectively connected to the two anti-collision rods;
[0023] And / or, a reset weight block is provided at the bottom of the container seat, and one end of the elastic member is connected to the reset weight block;
[0024] And / or, the base is further provided with a slide groove, which extends toward the mounting hole; the swing frame also includes a guide rod arranged on the rotating seat, and one end of the guide rod away from the rotating seat can be slidably extended into the slide groove.
[0025] In one embodiment, the lifting assembly includes a lifting motor, a synchronous wheel and a synchronous belt, wherein the lifting motor is arranged on the base plate, the output shaft of the lifting motor is provided with a driving wheel, the synchronous wheel is rotatably arranged on the base plate, and is spaced and arranged opposite to the driving wheel, the synchronous belt is sleeved on the driving wheel and the synchronous wheel, and the synchronous belt is fixedly connected to the base; wherein the lifting motor drives the driving wheel to rotate, so that the synchronous belt drives the base to lift and lower along the first direction;
[0026] And / or, the transverse shifting assembly includes a transverse shifting motor, a synchronous pulley and a transverse shifting belt, the transverse shifting motor is arranged on the mounting frame, the output shaft of the transverse shifting motor is provided with a driving pulley, the synchronous pulley is rotatably arranged on the mounting frame, and is spaced apart and arranged opposite to the driving pulley, the transverse shifting belt is sleeved on the driving pulley and the synchronous pulley, and the transverse shifting belt is fixedly connected to the base plate; wherein, the transverse shifting motor drives the driving pulley to rotate, so that the transverse shifting belt drives the base plate to move transversely along the second direction.
[0027] In one embodiment, the mixing device further includes a transverse movement detection component, the transverse movement detection component includes a mounting plate, a transverse movement optical coupler and a transverse movement baffle, the mounting plate is arranged on the mounting frame, the transverse movement optical coupler is arranged on the mounting plate, the transverse movement optical coupler is provided with a detection slot, one end of the transverse movement baffle is connected to the substrate, and the other end of the transverse movement baffle extends toward the mounting plate;
[0028] And / or, the mixing device further includes a lifting detection component, the lifting detection component includes a fixed frame, a lifting optical coupler and a lifting baffle, the fixed frame is arranged on the base plate, the lifting optical coupler is arranged on the fixed frame, the lifting optical coupler is provided with a detection port, one end of the lifting baffle is connected to the base, and the other end of the lifting baffle extends toward the base plate;
[0029] And / or, the mixing device also includes a rotation detection component, the rotation detection component includes a bracket, a rotating optical coupler and a rotating baffle, the bracket is arranged on the base, the rotating optical coupler is arranged on the bracket, the rotating optical coupler is provided with a detection notch, one end of the rotating baffle is connected to the driving component, and the other end of the rotating baffle extends toward the detection notch.
[0030] The present invention further provides a sample analyzer, comprising:
[0031] An equipment body, wherein the equipment body is provided with a disk and a plurality of reaction containers, the disk is provided with a plurality of mounting ports, and each of the reaction containers is detachably mounted on one of the mounting ports; and
[0032] The mixing device described above is arranged on the equipment body, and the containing cavity of the mixing device is opposite to one of the reaction containers.
[0033] The mixing device of the technical solution of the present invention is provided with a transverse movement component on the mounting frame, and the substrate of the lifting mechanism is movably arranged on the mounting frame and connected with the transverse movement component, and the base of the mixing mechanism is movably arranged on the base and connected with the lifting component installed on the base, so that the transverse movement component and the lifting component cooperate to realize the two-dimensional plane movement of the mixing mechanism in the first direction and the second direction; at the same time, by providing a driving component and a mixing component on the base of the mixing mechanism, the mixing component is provided as a swing frame and a container seat, and the swing frame is movably connected with the driving component provided on the base, so that the driving component is used to provide driving force for the mixing component, and the container seat is rotatably connected with the swing frame, and the accommodating cavity of the container seat is used to carry the reaction container, so that when the driving component drives the swing frame to rotate, the swing frame can be used to provide driving force for the container seat, The rotation of the swing frame can also be used to achieve the swing of the container seat relative to the swing frame, so as to improve the mixing effect of the sample in the reaction container placed in the accommodating chamber, and at the same time, cooperate with the driving of the lateral movement component so that when the mixing device is stationary, it is convenient for the container seat to realize vertical placement of the reaction container. When mixing, the swing angle of the container seat relative to the swing frame is increased, further improving the mixing effect of the sample in the reaction container placed in the accommodating chamber; further, the container seat and the reaction container rotate or swing at the same time, thereby effectively reducing the noise during mixing, and when the driving component of the mixing mechanism stops driving, the container seat of the mixing component and the swing frame are stationary or coaxially arranged, thereby facilitating the placement of the reaction container, avoiding lateral pressure on the positioning accuracy when the reaction container is inserted into and taken out of the accommodating chamber, and improving the positioning accuracy and reliability of taking and placing the reaction container. BRIEF DESCRIPTION OF THE DRAWINGS
[0034] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.
[0035] Figure 1 It is a structural schematic diagram of a mixing mechanism in one embodiment of the present invention;
[0036] Figure 2 A cross-sectional schematic diagram of a mixing mechanism in one embodiment of the present invention;
[0037] Figure 3 A partial structural schematic diagram of a mixing mechanism in one embodiment of the present invention;
[0038] Figure 4 A partially exploded schematic diagram of a mixing mechanism in one embodiment of the present invention;
[0039] Figure 5It is a cross-sectional schematic diagram of a mixing mechanism in another embodiment of the present invention;
[0040] Figure 6 It is a cross-sectional schematic diagram of a mixing mechanism in another embodiment of the present invention;
[0041] Figure 7 A schematic diagram of a partial structure of a mixing device in one embodiment of the present invention;
[0042] Figure 8 A partial cross-sectional schematic diagram of a mixing device in one embodiment of the present invention;
[0043] Fig. 9 A partial structural schematic diagram of a mixing device in another embodiment of the present invention;
[0044] Fig.10 It is a structural schematic diagram of a sample analyzer in one embodiment of the present invention;
[0045] Fig.11 FIG. 4 is a partial cross-sectional schematic diagram of a sample analyzer according to an embodiment of the present invention.
[0046] Description of Figure Numbers:
[0047]
[0048]
[0049] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0050] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0051] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.
[0052] At the same time, the meaning of "and / or" or "and / or" appearing in the full text includes three options. Taking "A and / or B" as an example, it includes option A, or option B, or a option in which both A and B are satisfied.
[0053] In addition, in the present invention, descriptions such as "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
[0054] Blood samples need to be fully mixed before measurement, otherwise the measurement results will have a large deviation. At present, when the analyzer measures peripheral blood samples, it is usually necessary to manually mix the samples by flicking them with your fingers before putting them into the analyzer for testing. However, this mixing method greatly limits the number of sample batch measurements and increases the burden of manual operation, which is extremely inconvenient.
[0055] In the related art, an abutment portion is provided in the cup holder for placing a reaction cup or a test tube, so that after the reaction cup or the test tube is inserted into the cup holder, the abutment portion can make the axis of the reaction cup or the test tube have a fixed angle α or eccentricity d with the axis of the cup holder. Such a setting causes the positioning accuracy to be subject to lateral pressure when the test tube is inserted and taken out, affecting the positioning accuracy and reliability of the cup, and more likely to cause the reaction cup to fail to grasp or insert and fall. At the same time, the angle between the reaction cup and the axis of the cup holder cannot be set too large. If it is set too large, the test tube cannot be inserted into the cup holder, and it is easier to drop the test tube. However, if the angle is set too small, the test tube is more difficult to move and mix in the horizontal plane, and the reaction cup holder is a rigid structure, so the noise is relatively large during mixing.
[0056] Based on the above ideas and problems, the present invention proposes a mixing device 700. It can be understood that the mixing device 700 is applied to the sample analyzer 900, so as to achieve mixing of the sample liquid contained in the reaction container 820, so that the sample analyzer 900 can detect the mixed sample liquid contained in the reaction container 820, thereby improving the detection accuracy.
[0057] Please refer to Figures 1 to 11As shown, in the embodiment of the present invention, the mixing device 700 includes a mounting frame 410, a lifting mechanism and a mixing mechanism 100, wherein the mounting frame 410 is provided with a lateral movement component 420, the lifting mechanism includes a base plate 510 and a lifting component 520 provided on the base plate 510, the base plate 510 is movably provided on the mounting frame 410 and connected to the lateral movement component 420, the mixing mechanism 100 includes a base 1, a driving component 2 and a mixing component 3, the base 1 is movably provided on the base plate 510 and connected to the lifting component 520, the driving component 2 is provided on the base 1, and the mixing mechanism 100 includes a base 1, a driving component 2 and a mixing component 3. The leveling component 3 includes a swing frame 31 and a container seat 32, the swing frame 31 is movably connected to the output shaft of the driving component 2, the container seat 32 is rotatably connected to the swing frame 31, and the container seat 32 is provided with a accommodating cavity 321, and the accommodating cavity 321 is used to carry the reaction container 820; wherein, the driving component 2 drives the swing frame 31 to rotate so that the container seat 32 swings relative to the swing frame 31, the lifting component 520 drives the base 1 to rise and fall along the first direction, and the transverse movement component 420 drives the substrate 510 to transversely move along the second direction, and the first direction and the second direction are set at an angle.
[0058] In this embodiment, the mounting frame 410 of the mixing device 700 is used to install, fix and support the transverse movement component 420, the lifting mechanism and the mixing mechanism 100 and other components, that is, to provide a mounting base for the transverse movement component 420, the lifting mechanism and the mixing mechanism 100 and other components, and to facilitate the installation and fixing of the mixing device 700 on the sample analyzer 900. It can be understood that the mounting frame 410 can be a mounting plate, a mounting frame, a mounting shell or a mounting platform and other structures, as long as it can realize the installation and fixing of the transverse movement component 420, the lifting mechanism and the mixing mechanism 100 and other components, and it is not limited here. Of course, in order to realize the assembly of the transverse movement component 420, the lifting mechanism and the mixing mechanism 100 and other components, and to achieve height adaptation, the mounting frame 410 can be formed with a mounting step or a gantry with a height difference and other structures, which are not limited here.
[0059] It can be understood that the transverse movement assembly 420 is used to provide driving force for the lifting mechanism and the mixing mechanism 100 and other components to move transversely along the second direction. The transverse movement assembly 420 can be a driving cylinder, a driving motor with a screw rod, a motor with a driving wheel or a transmission belt, etc., which is not limited here. In this embodiment, the lifting assembly 520 and the mixing mechanism 100 are installed on the mounting frame 410 as a whole by using the substrate 510, and connected to the transverse movement assembly 420, so that the transverse movement assembly 420 drives the substrate 510 to drive the lifting assembly 520 and the mixing mechanism 100 to move transversely along the second direction as a whole.
[0060] In this embodiment, the lifting assembly 520 is disposed on the substrate 510, so that the base 1 of the mixing mechanism 100 is movably connected to the substrate 510 and is in transmission connection with the lifting assembly 520, so that the lifting assembly 520 is used to provide a driving force for the lifting of the mixing mechanism 100 along the first direction to adjust the lifting position of the mixing mechanism 100 on the substrate 510. It can be understood that the lifting assembly 520 can be a driving cylinder, a driving motor with a screw rod, a motor with a driving wheel or a transmission belt, etc., which is not limited here.
[0061] It is understandable that the base 1 of the mixing mechanism 100 is used to install, fix and support components such as the drive assembly 2 and the mixing assembly 3, that is, the base 1 provides a mounting base for components such as the drive assembly 2 and the mixing assembly 3. It is understandable that the base 1 can be a mounting plate, a mounting frame, a mounting shell or a mounting platform, as long as it is a structure that can achieve the installation and fixing of components such as the drive assembly 2 and the mixing assembly 3, and is not limited here. Of course, in order to realize the assembly of components such as the drive assembly 2 and the mixing assembly 3, and to achieve height adaptation, a mounting step or a gantry with a height difference can be formed on the base 1, which is not limited here. The mixing mechanism 100 can be installed and fixed on the mixing device 700 through the base 1. Of course, the base 1 can also be integrally arranged on the mixing device 700, which is not limited here.
[0062] In this embodiment, the driving component 2 is used to provide driving force for the mixing component 3, thereby avoiding the use of human drive, saving manpower and improving efficiency. It can be understood that the driving component 2 can be a driving motor, a rotary motor, a servo motor or a driving cylinder, as long as it can provide driving force for the mixing component 3, and it is not limited here.
[0063] It can be understood that the mixing component 3 is configured as a two-part structure of a swing frame 31 and a container seat 32. By providing a accommodating cavity 321 on the container seat 32, the accommodating cavity 321 of the container seat 32 is utilized to accommodate, carry or limit the positioning and placement of the reaction container 820, thereby realizing the limiting and limiting placement of the reaction container 820; at the same time, the container seat 32 is rotatably connected to the swing frame 31, so that the driving component 2 drives the swing frame 31 to rotate, so that the container seat 32 swings relative to the swing frame 31, that is, the container seat 32 transmits mixing power to the reaction container 820, so that the container seat 32 and the reaction container 820 swing as a whole relative to the swing frame 31, so as to utilize the swinging to mix the sample liquid in the reaction container 820.
[0064] The mixing device 700 of the present invention is provided with a transverse movement component 420 on the mounting frame 410, and the substrate 510 of the lifting mechanism is movably arranged on the mounting frame 410 and connected to the transverse movement component 420, and the base 1 of the mixing mechanism 100 is movably arranged on the substrate 510 and connected to the lifting component 520 installed on the substrate 510, so that the transverse movement component 420 and the lifting component 520 cooperate to realize the two-dimensional plane movement of the mixing mechanism 100 in the first direction and the second direction; at the same time, by providing a driving component 2 and a mixing component 3 on the base 1 of the mixing mechanism 100, the mixing component 3 is provided as a swing frame 31 and a container seat 32, and the swing frame 31 is movably connected to the driving component 2 provided on the base 1, so that the driving component 2 is used to provide a driving force for the mixing component 3, and the container seat 32 is rotatably connected to the swing frame 31, and the accommodating cavity 321 of the container seat 32 is used to carry the reaction container 820, so that the driving component 2 drives the swing When the rack 31 rotates, the swing rack 31 can be used to provide a driving force for the container seat 32, and the swing rack 31 can be used to rotate to realize the swing of the container seat 32 relative to the swing rack 31, so as to improve the mixing effect of the sample in the reaction container 820 placed in the accommodating cavity 321, and at the same time cooperate with the driving of the transverse movement component 420, so that the swing angle of the container seat 32 relative to the swing rack 31 is increased, and the mixing effect of the sample in the reaction container 820 placed in the accommodating cavity 321 is further improved; further, the container seat 32 and the reaction container 820 rotate or swing at the same time, thereby effectively reducing the noise during mixing, and when the driving component 2 of the mixing mechanism 100 stops driving, the container seat 32 of the mixing component 3 and the swing rack 31 are stationary or coaxially arranged, so as to facilitate the placement of the reaction container 820, avoid the positioning accuracy of the reaction container 820 being subjected to lateral pressure when the reaction container 820 is inserted into and taken out of the accommodating cavity 321, and improve the positioning accuracy and reliability of the reaction container 820.
[0065] It can be understood that the mixing device 700 of the present invention solves the problem that the reaction container 820 cannot be placed vertically and the positioning accuracy is poor based on the fixed tilt mixing solution in the prior art. At the same time, the mixing mechanism 100 in the mixing device 700 of the present invention can also achieve the function of mixing the trace sample and collecting it to the bottom, and will not lose part of the sample and attach it to the side wall of the reaction container 820, resulting in the situation that the whole sample cannot be mixed.
[0066] In this embodiment, the reaction container 820 of the mixing mechanism 100 can be a round tube reaction cup, an inner octagonal round tube reaction cup, a vacuum blood collection tube, a micro vacuum blood collection tube, a square tube reaction cup, etc., which are not limited here. At the same time, the reaction container 820 applicable to the mixing mechanism 100 includes not only reaction cups for luminescence, but also reaction cups used in several other instruments, such as blood cells, biochemistry, coagulation, etc., that is, the mixing device 700 can be applied to the fields of blood cells, biochemistry, coagulation, etc., which are not limited here.
[0067] It can be understood that in the mixing device 700, a horizontally movable transverse movement component 420 is added on the basis of the lifting mechanism, so that the mixing mechanism 100 can be upwardly sleeved on the bottom of the reaction container 820 and then move horizontally, so that the axis of the placement hole of the top reaction container 820 coincides with the main axis of the crankshaft 22 of the mixing mechanism 100, so that during mixing, the axis of the reaction container 820 can be mixed around the main axis 221 of the crankshaft 22 to perform swing axis mixing within the conical surface; and when the reaction container 820 is inserted into and separated from the accommodating cavity 321 of the container seat 32, it will return to a vertical state, thereby avoiding malfunction of the reaction container 820.
[0068] In one embodiment, the base 1 is provided with a mounting hole 12, the driving assembly 2 includes a driving member 21 and a crankshaft 22, the crankshaft 22 includes a main shaft 221 and an eccentric shaft 222, one end of the main shaft 221 is rotatably arranged in the mounting hole 12, and is connected to the eccentric shaft 222, the axis of the eccentric shaft 222 is parallel to the axis of the crankshaft 22 and does not overlap, the eccentric shaft 222 is movably connected to the swing frame 31, the driving member 21 includes a rotating motor 211, a driven wheel 213 and a transmission belt 214, the rotating motor 211 is arranged on the base 1, the output shaft of the rotating motor 211 is provided with a driving wheel 212, the driven wheel 213 is sleeved on the main shaft 221, and the transmission belt 214 is sleeved on the driving wheel 212 and the driven wheel 213;
[0069] The rotating motor 211 drives the driving wheel 212 to rotate, so that the transmission belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate.
[0070] In this embodiment, if Figures 1 to 9 As shown, by setting the driving component 2 as a driving member 21 and a crankshaft 22, the crankshaft 22 is used to realize the connection between the driving member 21 and the swing frame 31, so that the driving member 21 provides driving force for the swing frame 31. It can be understood that the driving member 21 can be a driving motor, a transmission motor, a servo motor, a rotary motor, etc., which is not limited here. Of course, in other embodiments, the driving member 21 can also be a driving motor with a driving wheel, a driving gear or a synchronous belt, etc., which is not limited here.
[0071] In one embodiment, if Figures 1 to 9 As shown, the driving member 21 includes a rotating motor 211, a driven wheel 213 and a transmission belt 214, wherein the rotating motor 211 is arranged on the base 1, the output shaft of the rotating motor 211 is provided with a driving wheel 212, the driven wheel 213 is sleeved on the crankshaft 22, and the transmission belt 214 is sleeved on the driving wheel 212 and the driven wheel 213; wherein the rotating motor 211 drives the driving wheel 212 to rotate, so that the transmission belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate.
[0072] In this embodiment, the rotating motor 211 is fixedly installed on the base 1. In order to reasonably install the driving member 21 and connect the driving member 21 with the crankshaft 22, the output shaft of the rotating motor 211 rotates and passes through the base 1, and the output shaft of the rotating motor 211 is provided with a driving wheel 212, and the driven wheel 213 is sleeved on the crankshaft 22. The transmission belt 214 is sleeved on the driving wheel 212 and the driven wheel 213 to realize the transmission connection between the rotating motor 211 and the crankshaft 22.
[0073] It can be understood that when the rotating motor 211 drives the driving wheel 212 to rotate, the transmission belt 214 drives the driven wheel 213 and the crankshaft 22 to rotate. Optionally, the rotating motor 211 is a motor that provides power to the mixing component 3. In order to ensure the accuracy of the container seat 32 returning to its original position when the mixing is completed, the rotating motor 211 is optionally a stepping motor.
[0074] In this embodiment, if Figures 2 to 4 As shown, the crankshaft 22 includes a main shaft 221 and an eccentric shaft 222 connected to each other, one end of the main shaft 221 is transmission-connected to the driving member 21, that is, the driven wheel 213 is sleeved on the main shaft 221 of the crankshaft 22, and the other end of the main shaft 221 is rotationally penetrated through the mounting hole 12 and connected to the eccentric shaft 222. It can be understood that the main shaft 221 of the crankshaft 22 is rotationally connected to the base 1.
[0075] In one embodiment, if Figure 4 As shown, a bearing is provided in the mounting hole 12, and the main shaft 221 passes through the bearing and is connected to the eccentric shaft 222. It can be understood that the main shaft 221 is rotatably connected to the base 1 through the bearing.
[0076] In this embodiment, the eccentric shaft 222 of the crankshaft 22 and the driven wheel 213 are located on both sides of the base 1. Optionally, the diameter of the main shaft 221 of the crankshaft 22 is larger than the diameter of the eccentric shaft 222. Of course, in other embodiments, the diameter of the main shaft 221 of the crankshaft 22 may also be less than or equal to the diameter of the eccentric shaft 222, which is not limited here.
[0077] In one embodiment, if Figure 4 As shown, a mounting platform 223 is provided at one end of the main shaft 221 passing through the mounting hole 12, and the eccentric shaft 222 is provided at one end of the mounting platform 223 facing away from the main shaft 221 and located at the edge of the mounting platform 223, so that the axis of the eccentric shaft 222 is parallel to the axis of the crankshaft 22 and does not overlap.
[0078] In this embodiment, the axis of the main shaft 221 is parallel to the axis of the eccentric shaft 222 and does not overlap. Figure 2 , Figure 5 and Figure 6As shown, the distance between the axis of the eccentric shaft 222 and the axis of the crankshaft 22 is d. Optionally, the distance d between the axis of the eccentric shaft 222 and the axis of the crankshaft 22 ranges from 0.1 mm to 2 mm. For example, the distance d is 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, 1 mm, 1.3 mm, 1.5 mm, 1.8 mm, 2 mm, etc., which is not limited here.
[0079] It can be understood that, in such a configuration, when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the eccentric shaft 222 of the crankshaft 22 rotates around the axis of the main shaft 221, and at the same time, the axis of the eccentric shaft 222 is parallel to and does not overlap with the axis of the crankshaft 22, so that when the eccentric shaft 222 drives the swing frame 31 to rotate, the swing frame 31 will swing, so that the swing frame 31 drives the container seat 32 to swing. In this embodiment, the reaction container 820 and the container seat 32 have a common theoretical axis. When the container seat 32 drives the reaction container 820 to swing relative to the swing frame 31, the angle between the theoretical axis and the eccentric shaft 222 of the crankshaft 22 is α; in the static state without mixing, the angle α is 0, that is, the reaction container 820 and the container seat 32 are both in a vertical state; when mixing, the angle value is greater than 0.
[0080] At the same time, the problem that the angle between the reaction container 820 and the axis of the container seat 32 cannot be too large is solved; in this way, when not mixed, the reaction container 820 can be inserted into or removed from the accommodating cavity 321 of the container seat 32 in a vertical state, and the reaction container 820 is not easy to fall; and when mixing, a larger swing angle can be used to make it easier for the reagent to move back and forth in the horizontal plane in the reaction container 820 for mixing.
[0081] In this embodiment, when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the swing frame 31 drives the container seat 32 to rotate around the axis of the main shaft 221. After the swing frame 31 generates a swinging force, the container seat 32 can swing relative to the swing frame 31, thereby improving the mixing effect of the sample liquid in the reaction container 820.
[0082] In one embodiment, the swing frame 31 includes a rotating seat 311 and a support frame 312, wherein the rotating seat 311 is provided with a connecting hole 3111, and the end of the eccentric shaft 222 away from the main shaft 221 is rotated through the connecting hole 3111 through a bearing member, and the support frame 312 is arranged on the rotating seat 311, and the support frame 312 is provided with a swing groove 3123, and the container seat 32 can be swingably arranged in the swing groove 3123.
[0083] In this embodiment, if Figures 1 to 6As shown, the swing frame 31 is connected to the eccentric shaft 222 of the crankshaft 22 through the rotating seat 311. The rotating seat 311 is provided with a connecting hole 3111, and the eccentric shaft 222 is rotatably penetrated through the connecting hole 3111 through a bearing member, so that the eccentric shaft 222 is connected to the rotating seat 311.
[0084] It can be understood that the support frame 312 is disposed on the rotating seat 311, and the container seat 32 is swingably disposed in the swing groove 3123 by providing a swing groove 3123 on the support frame 312. In this embodiment, the container seat 32 is accommodated in the swing groove 3123, and the container seat 32 is rotatably connected or hingedly connected to the groove wall of the swing groove 3123, etc., which is not limited here.
[0085] This arrangement solves the problem that the angle between the reaction container 820 and the container seat 32 is a fixed value and cannot be changed; when the container seat 32 drives the reaction container 820 to swing back and forth relative to the rotating seat 311, the liquid in the reaction container 820 is more likely to be mixed by reciprocating motion in the horizontal direction. At the same time, it also solves the problem that the existing mixing structure has a large noise when mixing with a rigid structure.
[0086] In one embodiment, if Figure 2 , Figure 3 , Figure 5 and Figure 6 As shown, a clamping groove 224 is provided at one end of the eccentric shaft 222 away from the main shaft 221, and the driving assembly 2 further comprises a clamping ring 23, which is clamped in the clamping groove 224. It can be understood that by providing the clamping groove 224 on the eccentric shaft 222 and clamping the clamping ring 23 in the clamping groove 224, the clamping ring 23 is limitedly abutted against the bearing member in the connecting hole 3111 of the rotating seat 311, thereby improving the connection stability between the rotating seat 311 and the eccentric shaft 222.
[0087] In one embodiment, the support frame 312 includes a base 3121 and two support arms 3122, wherein the base 3121 is arranged on the rotating seat 311, and the two support arms 3122 are spaced apart on the side of the base 3121 facing away from the rotating seat 311, the two support arms 3122 are arranged opposite to each other, and cooperate with the base 3121 to form a swing groove 3123 and two through openings 3124 connecting the swing groove 3123, each support arm 3122 is provided with an axis hole 3125; the outer wall of the container seat 32 is provided with a rotating shaft 322 corresponding to each axis hole 3125, and the rotating shaft 322 is rotatably passed through the axis hole 3125.
[0088] In this embodiment, if Figure 1 , Figure 3 and Figure 4As shown, the base 3121 of the support frame 312 is fixedly connected to the rotating base 311 and is located on the side wall of the rotating base 311 facing away from the base 1. Optionally, the rotating base 311 is arranged parallel to the base 1. Two support arms 3122 are arranged at intervals and opposite to each other on the base 3121 of the support frame 312, so that the two support arms 3122 cooperate with the base 3121 to form a swing groove 3123 and two through openings 3124 connecting the swing groove 3123.
[0089] It can be understood that the two through openings 3124 of the support frame 312 are located at opposite sides of the swing groove 3123 and are connected to the swing groove 3123 . At this time, the line connecting the two through openings 3124 and the line connecting the two support arms 3122 are arranged vertically.
[0090] In this embodiment, an axial hole 3125 is provided on the support arm 3122, and a rotating shaft 322 is provided on the outer wall of the container seat 32 corresponding to each axial hole 3125. In this way, when the container seat 32 is accommodated in the swing groove 3123, the rotating shaft 322 is rotated to pass through the axial hole 3125, so as to realize the rotational connection between the container seat 32 and the support arm 3122.
[0091] Optionally, the shaft hole 3125 is located at one end of the support arm 3122 away from the base 3121, and the rotation shaft 322 is located at one end of the container seat 32 adjacent to the opening of the accommodating cavity 321. In this way, when the container seat 32 swings relative to the support frame 312 of the swing frame 31, the container seat 32 swings around the rotation shaft 322 in the swing groove 3123. Optionally, during the swinging process of the container seat 32, one end of the container seat 32 away from the rotation shaft 322 can pass through the through opening 3124 and extend out of the swing groove 3123, which is not limited here.
[0092] In one embodiment, the swing frame 31 also includes an anti-collision rod 313, which is arranged on the rotating seat 311 and corresponds to the through opening 3124; wherein, when the container seat 32 swings around the rotating shaft 322, one end of the container seat 32 away from the rotating shaft 322 extends out of the through opening 3124 and abuts against the anti-collision rod 313.
[0093] In this embodiment, if Figures 1 to 7 , Fig. 9 As shown, by setting the anti-collision rod 313, the anti-collision rod 313 is set corresponding to the through hole 3124, so that when the container seat 32 swings, the anti-collision rod 313 is used to limit the swing angle of the container seat 32, thereby preventing the container seat 32 from swinging too much and causing the sample liquid in the reaction container 820 to be spilled.
[0094] Understandable, such as Figure 2 , Figure 5 and Figure 6As shown, when the container seat 32 is stationary, the axis of the container seat 32 coincides with the axis of the eccentric shaft 222 of the crankshaft 22, and when the container seat 32 swings, the axis of the container seat 32 forms an angle α with the axis of the eccentric shaft 222 of the crankshaft 22, and the angle α is greater than 0. Optionally, the angle α is greater than 0 and less than or equal to 45°, for example, the angle α is 5°, 8°, 10°, 13°, 15°, 18°, 20°, 23°, 25°, 28°, 30°, 33°, 35°, 38°, 40°, 43°, 45°, etc., which is not limited here.
[0095] In this embodiment, the distance between the setting position of the anti-collision rod 313 on the rotating seat 311 and the opening 3124 is limited by the swing angle of the container seat 32, that is, when the container seat 32 swings, the angle α formed by the axis of the container seat 32 and the axis of the eccentric shaft 222 of the crankshaft 22 cannot be too large or too small. If the angle α is too large, it will easily cause the sample liquid in the reaction container 820 to be spilled; if the angle α is too small, it will lead to problems such as poor mixing effect of the sample liquid in the reaction container 820.
[0096] It can be understood that the anti-collision rod 313 is provided to limit the amplitude of the swing angle of the container seat 32 during the mixing process; when the mixing speed is large enough, the container seat 32 will swing and be blocked by the anti-collision rod 313.
[0097] In one embodiment, the swing frame 31 further includes an elastic member 314 , one end of the elastic member 314 is connected to the bottom of the container seat 32 , and the other end of the elastic member 314 is connected to the base 3121 or the anti-collision rod 313 .
[0098] In this embodiment, if Figure 5 and Figure 6 As shown, by setting the elastic member 314, one end of the elastic member 314 is connected to the bottom of the container seat 32, and the other end of the elastic member 314 is connected to the base 3121 or the anti-collision rod 313, so that the elastic member 314 can be used to reset the container seat 32 when the container seat 32 swings, and at the same time, it can also prevent the container seat 32 from swinging too much during the swinging process, thereby preventing the sample liquid in the reaction container 820 from being spilled.
[0099] Optionally, the elastic member 314 is a spring, such as a return spring, so that the elastic member 314 can be used to achieve buffering, reduce the vibration of the container seat 32, and thus reduce noise and splashing of liquid in the reaction container 820. Figure 5 As shown, one end of the elastic member 314 is connected to the bottom of the container seat 32, and the other end of the elastic member 314 is connected to the base 3121. In this embodiment, the anti-collision rod 313 may be provided or not provided, which is not limited here. Figure 6As shown, one end of the elastic member 314 is connected to the bottom of the container seat 32, and the other end of the elastic member 314 is connected to the anti-collision rod 313, which is not limited here.
[0100] In this configuration, the elastic member 314 can be used to tighten the container seat 32 and the base 3121 or the anti-collision rod 313, so that the container seat 32 and the reaction container 820 are in the original vertical state in the static state without mixing; in the mixing state, the elastic member 314 and the gravity of the container seat 32 jointly limit the swing angle of the container seat 32. It can be understood that the configuration of the elastic member 314 can also shorten the mixing time and increase the detection speed by increasing the rotation speed of the driving member 21.
[0101] Optionally, the anti-collision rod 313 includes two, and the two anti-collision rods 313 are respectively arranged on opposite sides of the base 3121 and respectively arranged corresponding to the two through openings 3124. The elastic member 314 includes two, and one end of the two elastic members 314 is connected to the bottom of the container seat 32, and the other end of the two elastic members 314 is respectively connected to the two anti-collision rods 313.
[0102] It can be understood that such a configuration can further ensure resetting, and can also prevent the container seat 32 from swinging too much during the swinging process, thereby causing the sample liquid in the reaction container 820 to be spilled.
[0103] In one embodiment, if Figure 1 , Figure 2 , Figure 5 and Figure 6 As shown, a reset weight block 323 is provided at the bottom of the container seat 32 , and one end of the elastic member 314 is connected to the reset weight block 323 .
[0104] It can be understood that the setting of the reset weight block 323, on the one hand, facilitates the connection between the elastic member 314 and the container seat 32, and on the other hand, the reset weight block 323 also plays a role in enabling the container seat 32 to quickly and statically reset when the driving member 21 stops working. That is, the reset weight block 323 is an additional weight added in the gravity reset solution, which is used to limit the deflection angle of the container seat 32 and the reaction container 820 when they are mixed, and reset them when they are not mixed.
[0105] In one embodiment, the base 1 is further provided with a slide groove 11, which extends toward the mounting hole 12; the swing frame 31 also includes a guide rod 315 arranged on the rotating seat 311, and one end of the guide rod 315 away from the rotating seat 311 can be slidably extended into the slide groove 11.
[0106] It can be understood that when the driving member 21 drives the crankshaft 22 to drive the rotating seat 311 to rotate, the guide rod 315 moves along the slide slot 11 to make the rotating seat 311 reciprocate along the extending direction of the slide slot 11 .
[0107] In this embodiment, if Figures 1 to 8 As described above, by providing the slide groove 11 on the base 1 and providing the guide rod 315 on the rotating seat 311 of the swing frame 31, the end of the guide rod 315 away from the rotating seat 311 can be slidably extended into the slide groove 11, so that when the driving member 21 drives the crankshaft 22 to drive the rotating seat 311 to rotate, the guide rod 315 moves along the slide groove 11, so that the rotating seat 311 reciprocates along the extension direction of the slide groove 11, thereby further ensuring the swing of the container seat 32. Optionally, a rolling bearing 3151 is provided at one end of the guide rod 315 extending into the slide groove 11, thereby improving the guiding effect.
[0108] It can be understood that the extension direction of the slide groove 11 is consistent with the swing direction of the container seat 32, that is, the extension direction of the slide groove 11 is parallel to or coincides with the line connecting the two openings 3124 on the swing frame 31, which is not limited here. That is, the scheme of the guide rod 315 and the slide groove 11 can be used to prevent the container seat 32 from rotating when rotating around the main shaft 221 of the crankshaft 22, so as to provide reciprocating motion for the guide bearing of the container seat 32 by using the structure of the guide rod 315 and the slide groove 11.
[0109] Of course, if Fig. 9 As shown, the guide rod 315 and the slide groove 11 structure may not be provided. In this way, when the driving member 21 drives the main shaft 221 of the crankshaft 22 to rotate, the eccentric shaft 222 drives the rotating seat 311 to rotate around the main shaft 221, and the rotating seat 311 can rotate around the eccentric shaft 222, thereby ensuring the mixing effect.
[0110] like Figures 1 to 8 As shown, for the solution of setting the guide rod 315 for the swing frame 31, the container seat 32 will swing back and forth left and right, so there are two left and right anti-collision rods 313; Fig. 9 As shown, for the solution in which the swing frame 31 is not provided with the guide rod 315 , the container seat 32 will only swing in the direction away from the main shaft 221 of the crankshaft 22 , so there is only one anti-collision rod 313 .
[0111] It can be understood that for the solution of setting the guide rod 315 for the swing frame 31, when the mixing device 700 is in a stationary and non-mixing state, the container seat 32 will rotate under the rotation of the crankshaft 22 driven by the rotating motor 211; when the rotating baffle 634 triggers the rotating optical coupler 632 and moves a certain distance, the rotating motor 211 stops; the container seat 32 stops at a fixed original position and returns to a stationary vertical state under the action of gravity or a spring, or both.
[0112] When the reaction container 820 is vertically inserted downward into the accommodating cavity 321 of the container seat 32, the cup-moving gripper of the reaction container 820 is separated from the reaction container 820 (the cup-moving gripper of the reaction container 820 can grab or put down the reaction container 820 from the vertical top of the reaction container 820, or can clamp or separate from the reaction container 820 from the side of the reaction container 820. Optionally, when the gripper clamps or separates from the reaction container 820 from the side, if there is a lateral force on the reaction container 820, the entry and exit direction of the gripper should be in the same direction as the swing axis of the container seat 32 to avoid the container seat 32 from having a swing angle that is not in a vertical state when the reaction container 820 is grasped or separated laterally).
[0113] The rotating motor 211 drives the crankshaft 22 to drive the container seat 32 to revolve around the main axis 221 of the crankshaft 22. At this time, the crank-connecting rod slider mechanism formed by the guide rod 315 and the crankshaft 22 in the horizontal plane restricts the container seat 32 from rotating around the eccentric shaft 222 of the crankshaft 22. The container seat 32 can only reciprocate around the horizontal axis of the container seat 32 in the vertical plane under the action of centrifugal force while revolving, so that the sample to be tested in the reaction container 820 simultaneously revolves, reciprocates and swings, and moves up and down, making it easier to mix.
[0114] When the mixing is finished, the container seat 32 returns to its original position and resets to a vertical state, the reaction container 820 is taken away, and the mixing is finished.
[0115] It can be understood that for the solution in which the swing frame 31 is not provided with the guide rod 315, the other steps are the same as the solution in which the swing frame 31 is provided with the guide rod 315; only when the container seat 32 starts to rotate and mix, the container seat 32 will rotate around the eccentric shaft 222 of the crankshaft 22 while revolving around the main shaft 221 of the crankshaft 22; therefore, the container seat 32 will only swing in the direction away from the outside of the main shaft 221 of the crankshaft 22; and no reciprocating swing in the vertical plane will occur. Of course, in order to achieve a good mixing effect, the mixing can be achieved by setting the rotating motor 211 to adopt a forward or reverse rotation mode, which is not limited here.
[0116] For all different reaction cups or test tube reaction containers 820, the above-mentioned swing frame 31 can be used with or without the guide rod 315. For the reset scheme of the container seat 32, the gravity reset scheme of the container seat 32 itself or the addition of a counterweight can be adopted, or the reset scheme of a single spring or a double spring acting together in the vertical plane can be adopted. It can be understood that in the spring reset scheme, the mixing speed of the container seat 32 of the mixing mechanism 100 can be relatively high and noiseless. In the gravity reset scheme, when the speed is low, the container seat 32 will not hit the anti-collision rod 313 and there will be no noise. If the anti-collision rod 313 adopts a harder elastic element, there will be no noise.
[0117] In one embodiment, the lifting assembly 520 includes a lifting motor 521, a synchronous wheel 523 and a synchronous belt 524. The lifting motor 521 is arranged on the substrate 510. The output shaft of the lifting motor 521 is provided with a driving wheel 522. The synchronous wheel 523 is rotatably arranged on the substrate 510 and is spaced and arranged opposite to the driving wheel 522. The synchronous belt 524 is sleeved on the driving wheel 522 and the synchronous wheel 523, and the synchronous belt 524 is fixedly connected to the base 1; wherein the lifting motor 521 drives the driving wheel 522 to rotate, so that the synchronous belt 524 drives the base 1 to rise and fall along the first direction.
[0118] In this embodiment, if Figures 7 to 11 As shown, the lifting motor 521 is fixedly mounted on the base plate 510. For reasonable assembly, the output shaft of the lifting motor 521 can rotatably pass through the base plate 510, and the output shaft of the lifting motor 521 is provided with a driving wheel 522, and the synchronous wheel 523 is rotatably arranged on the base plate 510, so that the synchronous wheel 523 and the driving wheel 522 are spaced and arranged oppositely, and the synchronous belt 524 is sleeved on the driving wheel 522 and the synchronous wheel 523. In this way, when the lifting motor 521 drives the driving wheel 522 to rotate, the synchronous belt 524 drives the synchronous wheel 523 to rotate.
[0119] It can be understood that the base 1 of the mixing mechanism 100 is provided with a fixing member, and the base 1 is fixedly connected to one side of the synchronous belt 524 through the fixing member, so that when the lifting motor 521 drives the driving wheel 522 to rotate forward or reverse, the synchronous belt 524 drives the base 1 to rise and fall. In this embodiment, the synchronous belt 524 is used in conjunction with the synchronous wheel 523 to be used as an idler wheel for tensioning and guiding the synchronous belt 524 and transmitting power. Optionally, the lifting motor 521 can be a stepping motor.
[0120] In one embodiment, if Figures 7 to 11 As shown, the base plate 510 is provided with a slide rail 511 , the slide rail 511 is parallel to and spaced from the synchronous belt 524 , and the base 1 is provided with a slide groove that slidably cooperates with the slide rail 511 .
[0121] It can be understood that by arranging the slide rail 511 on the base plate 510, and arranging the slide groove that slidably cooperates with the slide rail 511 on the base 1, the slide rail 511 is used to provide guidance for the lifting and lowering of the mixing mechanism 100. In this embodiment, the slide rail 511 and the slide groove can adopt a wedge-shaped limiting matching structure or a dovetail limiting matching structure, for example, the slide rail 511 is a wedge-shaped or dovetail-shaped structure, and the shape of the slide groove is adapted to the shape of the slide rail 511, so that the mixing mechanism 100 can achieve limiting matching with the slide rail 511 through the slide groove.
[0122] In one embodiment, the transverse movement assembly 420 includes a transverse movement motor 421, a synchronous pulley and a transverse movement belt 424. The transverse movement motor 421 is arranged on the mounting frame 410. The output shaft of the transverse movement motor 421 is provided with a driving pulley 422. The synchronous pulley is rotatably arranged on the mounting frame 410 and is spaced and arranged opposite to the driving pulley 422. The transverse movement belt 424 is sleeved on the driving pulley 422 and the synchronous pulley, and the transverse movement belt 424 is fixedly connected to the base plate 510; wherein, the transverse movement motor 421 drives the driving pulley 422 to rotate, so that the transverse movement belt 424 drives the base plate 510 to move transversely along the second direction.
[0123] In this embodiment, if Fig.10 and Fig.11 As shown, the transverse motor 421 is fixedly mounted on the mounting frame 410. For reasonable assembly, the output shaft of the transverse motor 421 can rotatably pass through the mounting frame 410, and the output shaft of the transverse motor 421 is provided with a driving pulley 422, and the synchronous pulley is rotatably arranged on the mounting frame 410, so that the synchronous pulley and the driving pulley 422 are spaced and arranged relatively, and the transverse belt 424 is sleeved on the driving pulley 422 and the synchronous pulley, so that when the transverse motor 421 drives the driving pulley 422 to rotate, the transverse belt 424 drives the synchronous pulley to rotate.
[0124] It can be understood that the base plate 510 of the lifting mechanism is provided with a fixing part, and the base plate 510 is fixedly connected to one side of the transverse belt 424 through the fixing part, so that when the transverse motor 421 drives the driving pulley 422 to rotate forward or reverse, the transverse belt 424 drives the base plate 510 to reciprocate along the second direction. In this embodiment, the transverse belt 424 is used in conjunction with the synchronous pulley to be used as an idler wheel for tensioning and guiding the transverse belt 424 and transmitting power. Optionally, the transverse motor 421 can be a stepping motor.
[0125] In one embodiment, if Fig.10 and Fig.11 As shown, the mounting frame 410 is provided with a guide rail 411 , which is parallel to and spaced from the transverse belt 424 , and the base plate 510 is provided with a guide groove which is slidably matched with the guide rail 411 .
[0126] It can be understood that by arranging the guide rail 411 on the mounting frame 410, and arranging the guide groove that slidably cooperates with the guide rail 411 on the base plate 510, the guide rail 411 is used to provide guidance for the lateral movement of the lifting mechanism and the mixing mechanism 100. In this embodiment, the guide rail 411 and the guide groove can adopt a wedge-shaped limiting cooperation structure or a dovetail limiting cooperation structure, for example, the guide rail 411 is a wedge-shaped or dovetail-shaped structure, and the shape of the guide groove is adapted to the shape of the guide rail 411, so that the base plate 510 of the lifting mechanism can achieve limiting cooperation with the guide rail 411 through the guide groove.
[0127] In this embodiment, the mixing device 700 adopts a two-dimensional mixing component solution of horizontal movement and vertical lifting, that is, a transverse movement component 420 is added on the basis of the lifting mechanism driving the mixing mechanism 100 to achieve lifting in the first direction, so that the transverse movement component 420 drives the lifting mechanism and the mixing mechanism 100 as a whole to achieve horizontal movement along the second direction; then the mixing mechanism 100 can be upwardly sleeved on the bottom of the reaction container 820 and then move horizontally, so that the axis of the placement hole of the top reaction container 820 coincides with the main axis 221 of the crankshaft 22, so that the axis of the reaction container 820 can be mixed around the main axis 221 within the cone surface during mixing; and when the reaction container 820 is inserted into and out of the accommodating cavity 321 of the container seat 32, it will return to the vertical state, thereby avoiding failure of the reaction container 820.
[0128] It can be understood that the horizontal and vertical lifting two-dimensional solution can enable the reaction container 820 such as the reaction cup and the test tube to be inserted or removed from the accommodating cavity 321 of the container seat 32 with the eccentricity d=0 and the swing angle α=0 to be inserted or removed in a fixed position state, and its positioning accuracy and guidance are more reliable. When eccentric mixing is required, that is, the eccentricity d>0 and the swing angle α>0, the horizontal lateral movement component 420 can change the size of the eccentricity d and the corresponding swing angle α. Correspondingly, if one-dimensional linear motion is further added on the basis of the horizontal and vertical two-dimensional components, the mixing device 700 becomes a three-dimensional mixing mechanism, which is not limited here.
[0129] In one embodiment, the mixing device 700 also includes a transverse movement detection component 610, which includes a mounting plate 611, a transverse movement optical coupler 612 and a transverse movement baffle. The mounting plate 611 is disposed on the mounting frame 410, the transverse movement optical coupler 612 is disposed on the mounting plate 611, the transverse movement optical coupler 612 is provided with a detection slot 613, one end of the transverse movement baffle is connected to the substrate 510, and the other end of the transverse movement baffle extends toward the mounting plate 611.
[0130] It can be understood that when the transverse movement assembly 420 drives the substrate 510 to move along the second direction of the mounting frame 410 , the substrate 510 drives the transverse movement baffle to pass through the detection slot 613 , so that the transverse movement optical coupler 612 can sense and detect.
[0131] In this embodiment, if Fig.10 and Fig.11 As shown, by setting the transverse movement detection component 610, the transverse movement optical coupler 612 of the transverse movement detection component 610 detects or senses the transverse movement baffle connected to the substrate 510 to control the working state of the transverse movement motor 421. It can be understood that the setting of the transverse movement detection component 610 can control the horizontal movement distance of the substrate 510 along the second direction of the mounting frame 410.
[0132] It can be understood that the lateral movement detection assembly 610 is fixed to the mounting frame 410 through the mounting plate 611, and the mounting plate 611 can be set on the mounting frame 410 by welding, bonding or integral molding, so as to improve the installation stability of the lateral movement detection assembly 610. Of course, the mounting plate 611 can also be detachably mounted on the mounting frame 410 by means of snap connection, plug-in fit, screw connection or pin connection, so as to improve the convenience of disassembly and assembly of the lateral movement detection assembly 610.
[0133] In this embodiment, the transverse optical coupler 612 can be an infrared sensor or an optical coupler sensor. By setting a detection slot 613, when the transverse baffle moves laterally with the substrate 510, the transverse baffle passes through the detection slot 613, so that the transverse optical coupler 612 senses and detects, and feeds back a signal to the transverse motor 421 to control the substrate 510 to move along the second direction of the mounting frame 410. Optionally, the transverse optical coupler 612 is electrically connected to the transverse motor 421, or the transverse optical coupler 612 is electrically connected to the main control system or controller or control circuit of the mixing device 700, which is not limited here. Optionally, the transverse baffle can be a sheet metal piece.
[0134] In one embodiment, the mixing device 700 also includes a lifting detection component 620, which includes a fixed frame 621, a lifting optical coupler 622 and a lifting baffle 624. The fixed frame 621 is arranged on the substrate 510, the lifting optical coupler 622 is arranged on the fixed frame 621, the lifting optical coupler 622 is provided with a detection port 623, one end of the lifting baffle 624 is connected to the base 1, and the other end of the lifting baffle 624 extends toward the substrate 510.
[0135] It can be understood that when the lifting assembly 520 drives the base 1 to move up and down along the substrate 510 , the base 1 drives the lifting baffle 624 to pass through the detection port 623 , so that the lifting optical coupler 622 can sense and detect.
[0136] In this embodiment, if Figures 7 to 10 As shown, by setting the lifting detection component 620, the lifting optical coupler 622 of the lifting detection component 620 detects or senses the lifting baffle 624 connected to the base 1 of the mixing mechanism 100 to control the working state of the lifting motor 521. It can be understood that the setting of the lifting detection component 620 can control the lifting height of the mixing mechanism 100 along the substrate 510.
[0137] It can be understood that the lifting detection component 620 is fixed on the base plate 510 through the fixing frame 621, and the fixing frame 621 can be set on the base plate 510 by welding, bonding or integral molding, so as to improve the installation stability of the lifting detection component 620. Of course, the fixing frame 621 can also be detachably installed on the base plate 510 by means of snap connection, plug-in fit, screw connection or pin connection, so as to improve the convenience of disassembly and assembly of the lifting detection component 620.
[0138] In this embodiment, the lifting optical coupler 622 can be an infrared sensor or an optical coupler sensor. By setting a detection port 623, when the lifting baffle 624 moves with the base 1 of the mixing mechanism 100, the lifting baffle 624 passes through the detection port 623, so that the lifting optical coupler 622 senses and detects, and feeds back a signal to the lifting motor 521 to control the lifting height of the mixing mechanism 100 along the substrate 510. Optionally, the lifting optical coupler 622 is electrically connected to the lifting motor 521, or the lifting optical coupler 622 is electrically connected to the main control system or controller or control circuit of the mixing device 700, which is not limited here. Optionally, the lifting baffle 624 can be a sheet metal piece.
[0139] In one embodiment, the mixing device 700 also includes a rotation detection component 630, which includes a bracket 631, a rotating optical coupler 632 and a rotating baffle 634. The bracket 631 is disposed on the base 1, the rotating optical coupler 632 is disposed on the bracket 631, the rotating optical coupler 632 is provided with a detection notch 633, one end of the rotating baffle 634 is connected to the driving component 2, and the other end of the rotating baffle 634 extends toward the detection notch 633.
[0140] It can be understood that when the driving member 21 of the mixing mechanism 100 drives the crankshaft 22 to rotate, the crankshaft 22 drives the rotating baffle 634 to pass through the detection notch 633 so that the rotating optical coupler 632 can sense and detect.
[0141] In this embodiment, if Figure 1 , Figure 7 , Fig. 9 and Fig.10 As shown, by setting a rotation detection component 630, the rotation optical coupler 632 of the rotation detection component 630 detects or senses the rotation baffle 634 connected to the crankshaft 22 of the mixing mechanism 100 to control the working state of the rotation motor 211 of the driving member 21. It can be understood that the setting of the rotation detection component 630 can control the rotation of the crankshaft 22 driven by the rotation motor 211.
[0142] It can be understood that the rotation detection component 630 is fixed to the base 1 of the mixing mechanism 100 through the bracket 631. The bracket 631 can be set on the base 1 by welding, bonding or integral molding, which can improve the installation stability of the rotation detection component 630. Of course, the bracket 631 can also be detachably installed on the base 1 by means of snap connection, plug-in fit, screw connection or pin connection, so as to improve the convenience of disassembly and assembly of the rotation detection component 630.
[0143] In this embodiment, the rotating optical coupler 632 can be an infrared sensor or an optical coupler sensor, and the detection notch 633 is set, so that when the rotating baffle 634 rotates with the crankshaft 22, the rotating baffle 634 passes through the detection notch 633, so that the rotating optical coupler 632 senses and detects, and feeds back a signal to the rotating motor 211 to control the rotation of the crankshaft 22 driven by the rotating motor 211. Optionally, the rotating optical coupler 632 is electrically connected to the rotating motor 211, or the rotating optical coupler 632 is electrically connected to the main control system or controller or control circuit of the mixing device 700, which is not limited here.
[0144] like Fig.10 and Fig.11 As shown, the present invention further proposes a sample analyzer 900, which includes a device body and the above-mentioned mixing device 700, and the mixing device 700 is arranged in the device body. The specific structure of the mixing device 700 refers to the above-mentioned embodiment. Since the present sample analyzer adopts all the technical solutions of all the above-mentioned embodiments, it has at least all the beneficial effects brought by the technical solutions of the above-mentioned embodiments, which will not be described one by one here.
[0145] In this embodiment, the equipment body is provided with a disc 810 and a plurality of reaction containers 820 , the disc 810 is provided with a plurality of mounting ports 811 , each reaction container 820 is detachably arranged at a mounting port 811 , the mixing device 700 is arranged at the equipment body, and the accommodating cavity 321 of the mixing device 700 is opposite to a reaction container 820 .
[0146] It is understandable that the reaction container 820 can be a reaction cup or a test tube. The reaction cup is used to provide a container for the instrument to add samples and reagents, react, mix, and detect. The test tube is a slender tubular bottle used to collect and store samples to be tested, which can be sealed with a cap or used without a cap.
[0147] In the present embodiment, the reaction cup or test tube can be selected as a round tube reaction cup, an inner octagonal round tube reaction cup, a vacuum blood collection tube, a micro vacuum blood collection tube or a square tube reaction cup, etc., which is not limited here. It can be understood that the inner and outer walls of the round tube reaction cup are cylindrical tubular reaction cups, especially the reaction cups used in the field of chemiluminescence. The inner wall of the inner octagonal round tube reaction cup is divided into two sections, the upper section is an inner octagonal round tube, and the lower section is a reaction cup of a cylindrical tube, especially the reaction cup used in the field of coagulation. The vacuum blood collection tube is especially exemplified by the cylindrical vacuum blood collection tube used for blood cells and biochemistry. The micro vacuum blood collection tube is especially exemplified by the micro vacuum blood collection tube used for blood cells, because the amount of samples to be tested is small, and the samples to be tested are not at the bottom of the test tube but in the middle of the test tube. The inner and outer walls of the square tube reaction cup are square or rectangular reaction cups, especially the square cup used in the field of chemiluminescence, which is not limited here.
[0148] The mixing device 700 of the present invention solves the problem in the prior art that when the reaction cup or test tube is inserted downward into the cup holder and descends to the end, it must have a fixed angle α or eccentricity d with the axis of the cup holder. It avoids the positioning accuracy being subjected to lateral pressure when the test tube is inserted and taken out, affecting the positioning accuracy and reliability of the cup, and avoiding the failure of the reaction cup to be grasped or inserted and dropped; it also solves the problem that the angle between the reaction cup and the axis of the cup holder cannot be too large; in this way, when not mixed, the test tube can be inserted or removed from the cup holder in a vertical state, and it is not easy to drop the test tube; and when mixing, it can make the reagent easier to reciprocate in the horizontal plane for mixing with a larger swing angle; it also solves the problem that the angle between the reaction cup and the cup holder is a fixed value and cannot be changed; it makes the liquid in the reaction cup easier to reciprocate in the horizontal direction for mixing when the reaction cup swings back and forth; it also solves the problem that the existing mixing structure is a rigid structure with high noise during mixing.
[0149] The above descriptions are only optional embodiments of the present invention, and are not intended to limit the patent scope of the present invention. All equivalent structural changes made using the contents of the present invention's specification and drawings, or directly / indirectly applied in other related technical fields, are included in the patent protection scope of the present invention.
Claims
1. A mixing device, characterized in that: The mixing device comprises: A mounting frame, wherein the mounting frame is provided with a transverse movement assembly; A lifting mechanism, the lifting mechanism comprising a base plate and a lifting assembly disposed on the base plate, the base plate being movably disposed on the mounting frame and connected to the transverse movement assembly; and A mixing mechanism, the mixing mechanism comprises a base, a driving assembly and a mixing assembly, the base is movably arranged on the base plate and connected to the lifting assembly, the driving assembly is arranged on the base, the mixing assembly comprises a swing frame and a container seat, the swing frame is movably connected to the output shaft of the driving assembly, the container seat is rotatably connected to the swing frame, the container seat is provided with a containing cavity, the containing cavity is used to carry the reaction container; the driving assembly comprises a crankshaft, the crankshaft comprises a main shaft and an eccentric shaft; The swing frame comprises: A rotating seat, wherein the rotating seat is provided with a connecting hole, and an end of the eccentric shaft away from the main shaft is rotatably penetrated through the connecting hole through a bearing member; and A support frame, the support frame is arranged on the rotating seat, the support frame is provided with a swinging groove, and the container seat is swingably arranged in the swinging groove; the support frame includes a base and two support arms, the base is arranged on the rotating seat; the two support arms are arranged at intervals on the side of the base facing away from the rotating seat, the two support arms are arranged opposite to each other, and cooperate with the base to form the swinging groove and two through ports connected to the swinging groove, each of the support arms is provided with an axis hole; the outer wall of the container seat is provided with a rotating shaft corresponding to each of the axis holes, and the rotating shaft is rotatably penetrated through the axis hole; Among them, the driving component drives the swing frame to rotate so that the container seat swings relative to the swing frame, the lifting component drives the base to rise and fall in a first direction, and the transverse movement component drives the substrate to move transversely in a second direction. The first direction and the second direction are set at an angle. When the driving component of the mixing mechanism stops driving, the container seat of the mixing component and the swing frame are stationary or coaxially set.
2. The mixing device according to claim 1, characterized in that: The base is provided with a mounting hole, the crankshaft includes a main shaft and an eccentric shaft, one end of the main shaft is rotatably inserted into the mounting hole and connected to the eccentric shaft, the axis of the eccentric shaft is parallel to and does not overlap with the axis of the crankshaft, the eccentric shaft is movably connected to the swing frame, the driving assembly also includes a driving member, the driving member includes a rotating motor, a driven wheel and a transmission belt, the rotating motor is provided on the base, the output shaft of the rotating motor is provided with a driving wheel, the driven wheel is sleeved on the main shaft, and the transmission belt is sleeved on the driving wheel and the driven wheel; Wherein, the rotating motor drives the driving wheel to rotate, so that the transmission belt drives the driven wheel and the crankshaft to rotate.
3. The mixing device according to claim 2, characterized in that: The swing frame further includes an anti-collision rod, which is arranged on the rotating seat and corresponds to the through opening; When the container seat swings around the rotating shaft, one end of the container seat away from the rotating shaft extends out of the through opening and abuts against the anti-collision rod.
4. The mixing device according to claim 3, characterized in that: The swing frame also includes an elastic member, one end of which is connected to the bottom of the container seat, and the other end of which is connected to the base or the anti-collision rod.
5. The mixing device according to claim 4, characterized in that: The anti-collision rods include two, the two anti-collision rods are respectively arranged on opposite sides of the base and are respectively arranged corresponding to the two through openings, the elastic members include two, one end of the two elastic members is connected to the bottom of the container seat, and the other ends of the two elastic members are respectively connected to the two anti-collision rods; And / or, a reset weight block is provided at the bottom of the container seat, and one end of the elastic member is connected to the reset weight block; And / or, the base is further provided with a slide groove, which extends toward the mounting hole; the swing frame also includes a guide rod arranged on the rotating seat, and one end of the guide rod away from the rotating seat can be slidably extended into the slide groove.
6. The mixing device according to any one of claims 1 to 5, characterized in that: The lifting assembly comprises a lifting motor, a synchronous wheel and a synchronous belt, wherein the lifting motor is arranged on the base plate, the output shaft of the lifting motor is provided with a driving wheel, the synchronous wheel is rotatably arranged on the base plate, and is spaced and arranged opposite to the driving wheel, the synchronous belt is sleeved on the driving wheel and the synchronous wheel, and the synchronous belt is fixedly connected to the base; wherein the lifting motor drives the driving wheel to rotate, so that the synchronous belt drives the base to lift and lower along the first direction; And / or, the transverse shifting assembly includes a transverse shifting motor, a synchronous pulley and a transverse shifting belt, the transverse shifting motor is arranged on the mounting frame, the output shaft of the transverse shifting motor is provided with a driving pulley, the synchronous pulley is rotatably arranged on the mounting frame, and is spaced apart and arranged opposite to the driving pulley, the transverse shifting belt is sleeved on the driving pulley and the synchronous pulley, and the transverse shifting belt is fixedly connected to the base plate; wherein, the transverse shifting motor drives the driving pulley to rotate, so that the transverse shifting belt drives the base plate to move transversely along the second direction.
7. The mixing device according to any one of claims 1 to 5, characterized in that: The mixing device further includes a transverse movement detection component, which includes a mounting plate, a transverse movement optical coupler and a transverse movement baffle, wherein the mounting plate is arranged on the mounting frame, the transverse movement optical coupler is arranged on the mounting plate, the transverse movement optical coupler is provided with a detection slot, one end of the transverse movement baffle is connected to the base plate, and the other end of the transverse movement baffle extends toward the mounting plate; And / or, the mixing device further includes a lifting detection component, the lifting detection component includes a fixed frame, a lifting optical coupler and a lifting baffle, the fixed frame is arranged on the base plate, the lifting optical coupler is arranged on the fixed frame, the lifting optical coupler is provided with a detection port, one end of the lifting baffle is connected to the base, and the other end of the lifting baffle extends toward the base plate; And / or, the mixing device also includes a rotation detection component, the rotation detection component includes a bracket, a rotating optical coupler and a rotating baffle, the bracket is arranged on the base, the rotating optical coupler is arranged on the bracket, the rotating optical coupler is provided with a detection notch, one end of the rotating baffle is connected to the driving component, and the other end of the rotating baffle extends toward the detection notch.
8. A sample analyzer, characterized in that: The sample analyzer comprises: An equipment body, wherein the equipment body is provided with a disk and a plurality of reaction containers, the disk is provided with a plurality of mounting ports, and each of the reaction containers is detachably mounted on one of the mounting ports; and The mixing device as described in any one of claims 1 to 7, wherein the mixing device is arranged on the equipment body, and the accommodating chamber of the mixing device is opposite to one of the reaction containers.
Citation Information
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