Biological detection device and refrigerator

Abstract

The present application relates to a biological detection device and a refrigerator, the biological detection device comprising: a support having a chip mounting portion for mounting at least one biological detection chip, a plurality of fluid interfaces being formed on the chip mounting portion for one-to-one correspondence with a plurality of detection channels formed in the at least one biological detection chip; and a driving mechanism arranged on the support and communicated with each fluid interface, so that after the at least one biological detection chip is mounted on the chip mounting portion, the driving mechanism is communicated with the plurality of detection channels through the plurality of fluid interfaces respectively, thereby controlledly driving the fluid flow in each detection channel. The biological detection device can simultaneously control the detection process of different detection parameters of the same sample or different detection parameters of different samples, reduce the energy consumed in the detection process, reduce the detection time, simplify the detection process, improve the detection efficiency, and improve the user's use experience.

Description

Technical Field

[0001] The present invention relates to refrigeration and freezing technology, in particular to a biological detection device and a refrigerator. Background Art

[0002] As people's living standards improve, they often need to test some of the food they eat for pesticide residues, viruses, nutrients, or other aspects in their daily lives to qualitatively or quantitatively determine the condition of the food. For example, due to the overuse of pesticides, the fruits, vegetables, and agricultural and sideline products we buy daily may contain excessive levels of pesticide residues. If these excessive levels of pesticide residues are not detected in a timely manner, they can cause great harm to the human body after ingestion. For another example, breastfeeding, which is currently advocated, is the best way to feed babies only when breast milk has normal nutritional value. However, if a nursing mother is ill, taking medication, undergoing surgery, or in other circumstances, the nutrient content of her milk may decrease or even contain viruses, thereby affecting the growth, development, and health of the baby.

[0003] Among the many detection methods, the method of using biological detection chips for detection is relatively fast, small in size, and suitable for home use. In order to facilitate the control of the detection process of the biological detection chip, a driving device can be used to drive the flow of fluid in the biological detection chip. However, the existing biological detection device for biological detection chips can only control one detection flow path of a biological detection chip at a time. If the user needs to detect multiple different samples or different parameters of the same sample, multiple biological detection chips need to be installed on the biological detection device for multiple detections, which is time-consuming and material-intensive, and has high costs. In addition, the chip needs to be replaced multiple times, the operation is complicated, and the user experience is poor. Summary of the Invention

[0004] An object of the first aspect of the present invention is to overcome at least one drawback of the prior art and to provide a biological detection device capable of simultaneously controlling the flow of fluids in multiple detection channels.

[0005] A further object of the first aspect of the present invention is to simplify the structure of the biological detection device.

[0006] Another further object of the first aspect of the present invention is to improve the accuracy of fluid flow control within each detection channel.

[0007] The second aspect of the present invention is to provide a refrigerator having the biological detection device according to any of the above solutions.

[0008] According to a first aspect of the present invention, the present invention provides a biological detection device comprising:

[0009] A support having a chip mounting portion for mounting at least one bio-detection chip, the chip mounting portion having a plurality of fluid interfaces formed thereon for one-to-one correspondence with a plurality of detection channels formed in the at least one bio-detection chip; and

[0010] A driving mechanism disposed on the support and in communication with each of the fluid interfaces for enabling the driving mechanism to communicate with the plurality of detection channels through the plurality of fluid interfaces respectively after the at least one bio-detection chip is mounted to the chip mounting portion, thereby controllably driving fluid flow in each of the detection channels.

[0011] Optionally, the support has a connection channel formed therein, one end of the connection channel being in communication with the driving mechanism and the other end having a plurality of branch channels, the plurality of branch channels being in one-to-one correspondence with the plurality of fluid interfaces respectively for enabling the driving mechanism to drive fluid in the plurality of detection channels of the at least one bio-detection chip mounted in the chip mounting portion simultaneously.

[0012] Optionally, the driving mechanism is a micro-injection pump for facilitating fluid flow in the detection channels by means of air pressure.

[0013] Optionally, the driving mechanism comprises:

[0014] a driving motor for outputting a driving force;

[0015] a screw rod connected to the driving motor for rotation under the driving of the driving motor;

[0016] a sliding block penetrating the screw rod and threadedly connected to the screw rod for translation along the screw rod under the rotation of the screw rod;

[0017] a syringe having a first end in communication with the connection channel; and

[0018] a piston disposed inside the syringe and fixedly connected to the sliding block for movement in the syringe under the driving of the sliding block, thereby facilitating fluid flow in the detection channels when the piston moves towards the first end of the syringe.

[0019] Optionally, a section of the driving motor connected to the screw rod is fixedly supported on the support, and an end of the driving motor away from the screw rod and a circumferential side of the driving motor are both spaced apart from the support.

[0020] Optionally, the bio-detection device further comprises:

[0021] A position sensor is used to detect the position of the slider to control the operation of the drive motor according to the position of the slider, thereby controlling the path of fluid flow in the detection channel by controlling the displacement of the piston in the syringe.

[0022] Optionally, the biological detection device further includes:

[0023] A circuit board is fixed on the bracket, and the position sensor is arranged on the circuit board and electrically connected to the circuit board.

[0024] Optionally, the slider is provided with a bump protruding toward the circuit board, and a through slot for the bump to move therein is provided on a side of the circuit board facing the slider, and the position sensor is arranged adjacent to the outside of the through slot.

[0025] Optionally, the biological detection device further includes:

[0026] A front cover is provided on the front side of the bracket and has a notch;

[0027] The chip mounting portion is exposed to the front side of the front cover through the notch.

[0028] According to a second aspect of the present invention, the present invention further provides a refrigerator comprising the biological detection device involved in any of the above solutions.

[0029] The bioassay device of the present invention comprises a chip mounting portion for mounting a bioassay chip. The chip mounting portion is formed with multiple fluid interfaces for communicating with multiple detection channels in a one-to-one correspondence. A drive mechanism simultaneously communicates with the multiple fluid interfaces, facilitating simultaneous control of fluid flow within the multiple detection channels by the drive mechanism. The multiple detection channels can be used to detect different detection parameters for the same sample or different detection parameters for different samples. Thus, the bioassay device can simultaneously control the detection process for different detection parameters for the same sample or different samples, reducing energy consumption and detection time, simplifying the detection process, improving detection efficiency, and enhancing the user experience.

[0030] Moreover, the biological detection chip and the driving mechanism are both arranged on the bracket, so that the biological detection device and the biological detection chip form a system with a compact layout and integrated structure, thereby facilitating the integration of the system into a refrigerator or other household appliances for easy storage and use.

[0031] Furthermore, the present application designs the connecting channels for connecting the driving mechanism and various fluid interfaces inside the bracket, avoiding the problems of external connecting pipes between the driving mechanism and various fluid interfaces, which result in difficult layout, bulky volume, and easy interference with other structures. It simplifies the structure of the biological detection device and makes it more suitable for integration into refrigerators or other household appliances.

[0032] Furthermore, the present application also controls the displacement of the driving mechanism's piston in its syringe by detecting the position of the slider of the driving mechanism through a position sensor, thereby controlling the path of the fluid flow in the detection channel, making it easier to monitor the position of the piston and the displacement of its movement, thereby achieving precise control of the fluid flow path.

[0033] Based on the following detailed description of specific embodiments of the present invention in conjunction with the accompanying drawings, those skilled in the art will become more aware of the above and other objects, advantages and features of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Hereinafter, some specific embodiments of the present invention will be described in detail in an exemplary and non-limiting manner with reference to the accompanying drawings. The same reference numerals in the accompanying drawings indicate the same or similar components or parts. It should be understood by those skilled in the art that these drawings are not necessarily drawn to scale. In the accompanying drawings:

[0035] Figure 1 is a schematic structural diagram of a biological detection device according to one embodiment of the present invention;

[0036] Figure 2 and Figure 3 They are schematic structural exploded views of a biological detection device in different orientations according to an embodiment of the present invention;

[0037] Figure 4 is a schematic cross-sectional view of a biological detection device according to one embodiment of the present invention;

[0038] Figure 5 is a schematic front perspective view of a biological detection device according to one embodiment of the present invention;

[0039] Figure 6 and Figure 7 Schematic cross-sectional views of a biological detection chip according to an embodiment of the present invention taken along different cutting lines;

[0040] Figure 8 is a schematic cross-sectional view of a biological detection chip installed in a biological detection device according to one embodiment of the present invention;

[0041] Figure 9 yes Figure 8 Schematic enlarged view of the middle part A;

[0042] Figure 10 is a schematic flow chart of a control method of a biological detection device according to one embodiment of the present invention;

[0043] Figure 11 is a schematic structural diagram of a refrigerator according to one embodiment of the present invention;

[0044] Figure 12 1 is a schematic structural exploded view of a door body according to one embodiment of the present invention. DETAILED DESCRIPTION

[0045] The present invention first provides a biological detection device. Figure 1 is a schematic structural diagram of a biological detection device according to an embodiment of the present invention, Figure 2 and Figure 3 They are schematic structural decomposition diagrams of a biological detection device according to an embodiment of the present invention in different orientations. Figures 1 to 3 The biological detection device 1 of the present invention includes a bracket 10 and a driving mechanism 30.

[0046] The bracket 10 has a chip mounting portion 11 for mounting at least one biological detection chip. The chip mounting portion 11 is formed with multiple fluid interfaces 111 for communicating one-to-one with multiple detection channels formed in the at least one biological detection chip. Specifically, the multiple detection channels can be independent of each other and do not affect each other. In addition, the multiple detection channels can be formed in multiple biological detection chips respectively. In this case, the chip mounting portion 11 can simultaneously mount multiple biological detection chips. The multiple detection channels can also be formed in the same biological detection chip. In this case, the multiple detection channels formed in the biological detection chip can be isolated from each other and not connected to each other. The biological detection chip is used to perform qualitative or quantitative detection of preset detection parameters of the sample. The preset detection parameters can, for example, be pesticide residue parameters used to indicate whether the pesticide residue exceeds the standard and / or the specific value of the pesticide residue, nutritional parameters used to indicate whether a nutrient element meets the standard and / or the specific content of the nutrient element, specific substance parameters used to indicate whether a specific harmful substance (such as a specific virus) exceeds the standard and / or the specific content, etc.

[0047] The driving mechanism 30 is disposed on the bracket 10 and is connected to each fluid interface 111, so that after at least one biological detection chip is installed on the chip mounting portion 11, the driving mechanism 30 is connected to the multiple detection channels through the multiple fluid interfaces 111, thereby driving the fluid flow in each detection channel in a controlled manner. In other words, the driving mechanism 30 is connected to the multiple fluid interfaces 111 at the same time, so that the fluid flow in the multiple detection channels can be controlled simultaneously by the driving mechanism 30. The multiple detection channels can be used to detect different detection parameters of the same sample or different detection parameters of different samples. Thus, the biological detection device 1 can simultaneously control the detection process of different detection parameters of the same sample or different detection parameters of different samples, thereby reducing the energy consumed in the detection process, reducing the detection time, simplifying the detection process, improving the detection efficiency, and enhancing the user experience.

[0048] Moreover, the biological detection chip and the driving mechanism 30 are both supported on the bracket 10, so that the biological detection device 1 and the biological detection chip form a biological detection system with a compact layout and integrated structure, thereby facilitating the integration of the biological detection system into a refrigerator or other household appliances for easy storage and use.

[0049] Figure 4 is a schematic cross-sectional view of a biological detection device according to one embodiment of the present invention, Figure 5 This is a schematic front perspective view of a biological detection device according to one embodiment of the present invention. In some embodiments, a connecting channel 12 is formed within the support 10. One end of the connecting channel 12 communicates with the drive mechanism 30, and the other end has multiple branch channels 121. These branch channels 121 are connected to multiple fluid interfaces 111 in a one-to-one correspondence, allowing the drive mechanism 30 to simultaneously drive the fluid within multiple detection channels of the biological detection chip mounted in the chip mounting portion 11.

[0050] In the present application, the connection channel 12 for connecting the driving mechanism 30 and each fluid interface 111 is designed inside the bracket 10, avoiding the problem of external connecting pipes between the driving mechanism 30 and each fluid interface 111, which makes the layout difficult, bulky, and easy to interfere with other structures. This simplifies the structure of the biological detection device 1, making it more suitable for integration into a refrigerator or other household appliances.

[0051] Specifically, the chip mounting portion 111 can be located at the front side of the bracket 10, facilitating the user to install the bio-detection chip. The driving mechanism 30 can be located at the rear side of the bracket 10, so as to avoid its exposure to the outside of the bio-detection device 1 affecting the appearance. The connecting passage 12 can further comprise an inclined passage 122 connected between the driving mechanism 30 and each branch passage 121. When the driving mechanism 30 is located at the upper portion of the bracket 10 and the chip mounting portion 111 is formed at the lower portion of the bracket 10, the inclined passage 122 extends from top to bottom, rear to front.

[0052] In some embodiments, the driving mechanism 30 is a micro-injection pump, which promotes the flow of fluid in the detection passage by means of injecting air into the detection passage. When the driving mechanism 30 injects air into the detection passage, the pressure in the detection passage increases, and the fluid in the detection passage flows under the action of the pressure difference between the inside and outside of the detection passage.

[0053] Specifically, the driving mechanism 30 can comprise a driving motor 31, a screw rod 32, a sliding block 33, an injector 34 and a piston 35. The driving motor 31 is used to output driving force. The screw rod 32 is connected with the driving motor 31, so as to rotate under the driving of the driving motor 31. The sliding block 33 is arranged on the screw rod 32 and threadedly connected with the screw rod 32, so as to translate along the screw rod 32 with the rotation of the screw rod 32. The first end of the injector 34 is in communication with the connecting passage 12. The piston 35 is arranged inside the injector 34 and fixedly connected with the sliding block 33, so as to move in the injector 34 under the driving of the sliding block 33, thereby promoting the flow of fluid in the detection passage when the piston 35 moves towards the first end of the injector 34.

[0054] Further, a section of the driving motor 31 connected with the screw rod 32 is fixedly supported on the bracket 10, and the end of the driving motor 31 away from the screw rod 32 and the circumferential side of the driving motor 31 are both spaced apart from the bracket 10. That is, the driving motor 31 is not in contact with the bracket 10 except for the end thereof fixedly connected with the bracket 10. Thus, sufficient space is provided for heat dissipation of the driving motor 31, which is conducive to the timely dissipation of heat generated by the driving motor 31. Moreover, the transmission of vibration generated by the driving motor 31 to other components (for example, the bio-detection chip mounted on the chip mounting portion) on the bracket 10 is reduced to a certain extent, avoiding the influence on the other components.

[0055] In some embodiments, the driving mechanism 30 is a micro-injection pump, which promotes the flow of fluid in the detection passage by means of injecting air into the detection passage. When the driving mechanism 30 injects air into the detection passage, the pressure in the detection passage increases, and the fluid in the detection passage flows under the action of the pressure difference between the inside and outside of the detection passage. Figures 1 to 5Taking the bioassay device 1 shown in a vertical position as an example, the upper portion of the support 10 may be formed with two accommodating chambers, both of which are rearwardly open to accommodate a drive motor 31 and a syringe 34, respectively. The drive motor 31 may be housed within the upper first accommodating chamber 15. The bottom of the drive motor 31 is fixedly connected to the horizontally extending bottom plate 13 of the first accommodating chamber 15. The top and circumferential sides of the drive motor 31 are spaced a distance from the top plate and circumferential side plates of the first accommodating chamber 15, respectively. In other words, the top and circumferential sides of the drive motor 31 do not contact other structures of the support 10. A screw 32 is connected to the bottom of the drive motor 31 and extends vertically. The syringe 34 is housed within the lower second accommodating chamber 16, with the first end of the bottom of the syringe 34 in sealed communication with the connecting channel 12. A piston 35 is inserted into the syringe 34 through the second end of the top of the syringe 34 and may be fixedly connected to the slider 33 by threading, welding, gluing, or other suitable means. When the slider 33 drives the piston 35 to move downward, the piston 35 pushes the air in the syringe 34, and further pushes the air in the detection channel of the biological detection chip in the chip mounting portion 11, generating a relatively high pressure therein.

[0056] The detection channel in the biological detection chip usually includes multiple chambers with different functions, for example, a sampling chamber for holding an extract to obtain a sample liquid and a detection chamber for holding a detection reagent. In the detection of some parameters, such as pesticide residue detection, the sample liquid flowing out of the sampling chamber needs to enter a reaction chamber for holding a reaction reagent before entering the detection chamber. After the sample liquid reacts fully with the reaction reagent, it enters the detection chamber to react with the detection reagent to obtain the detection result. Since the preparation of the sample liquid and the reaction between the sample liquid and the reaction reagent both require time, and the detection channel of the biological detection chip is connected after installation, the flow position and flow time of the sample liquid in the detection channel need to be precisely controlled to ensure the accuracy of the detection result. In other words, during the operation of the drive mechanism 30, the movement amount and movement time of the piston 35 are very critical.

[0057] To this end, in some embodiments, the biological detection device 1 further includes a position sensor 92, which is used to detect the position of the slider 33, so as to control the operation of the drive motor 31 through the position of the slider 33, thereby controlling the path of fluid flow in the detection channel by controlling the displacement of the piston 35 in the syringe 34, thereby facilitating monitoring the position of the piston 35 and the displacement of its movement, thereby achieving precise control of the fluid flow path.

[0058] In some embodiments, the biological detection device 1 further includes a circuit board 93, which is fixed to the bracket 10. Specifically, the circuit board 93 can be fixed to the upper portion of the bracket 10, in front of the drive mechanism 30. A plurality of claws 14 can extend forward from the upper portion of the bracket 10 to engage the circuit board 93 therewith.

[0059] Furthermore, the position sensor 92 may be disposed on the circuit board 93 and electrically connected to the circuit board 93 .

[0060] In some embodiments, the slider 33 is provided with a protrusion 331 protruding toward the circuit board 93, and the side of the circuit board 93 facing the slider 33 is provided with a through groove 931 for the protrusion 331 to move therein, and the position sensor 92 is arranged adjacent to the outer side of the through groove 931 to facilitate detection of the position of the protrusion 331, thereby detecting the position of the slider 33.

[0061] In some embodiments, the biological detection device 1 also includes a front cover 91, which is arranged on the front side of the bracket 10, thereby covering at least part of the structure of the bracket 10, preventing the bracket 10, and the circuit board 93 and the driving mechanism 30 installed on the bracket 10 from being exposed on the front side of the biological detection device 1 and affecting its appearance.

[0062] Furthermore, a notch 911 is formed on the front cover 91 , and the chip mounting portion 11 is exposed to the front side of the front cover 91 through the notch 911 , so that the biological detection chip can be mounted on the chip mounting portion 11 through the notch 911 .

[0063] Figure 6 and Figure 7 are schematic cross-sectional views of a biological detection chip according to an embodiment of the present invention taken along different cutting lines, Figure 8 is a schematic cross-sectional view of a biological detection chip installed in a biological detection device according to one embodiment of the present invention. Figure 9 yes Figure 8 Schematic enlarged view of the middle portion A. The biological detection chip 2 of the present invention is used to match the biological detection device involved in any of the above embodiments.

[0064] In particular, the biological detection chip 2 includes a plurality of detection channels 20 that are arranged in parallel and independent of each other. It should be noted that the parallel arrangement mentioned here means that the flow channels in each detection channel 20 are isolated and independent from each other, and the fluid in each detection channel will not flow through other detection channels. In other words, the multiple detection channels 20 do not affect each other, and each detection channel 20 can independently detect one of the detection parameters of a sample, and the multiple detection channels 20 can simultaneously detect multiple different samples or multiple different parameters of the same sample. Compared with the traditional biological detection chip with only one detection channel, the biological detection chip 2 of the present application saves the materials required for detection, reduces the number of times the user installs and replaces the chip, thereby reducing the detection time, simplifying the detection process, improving the detection efficiency, and enhancing the user experience.

[0065] Specifically, multiple detection channels 20 are arranged side by side along the width direction of the biological detection chip 2, and each detection channel 20 extends along the length direction of the biological detection chip 2, so that the layout on the biological detection chip 2 is more compact, thereby reducing the volume of the biological detection chip 2, making it more suitable for integration into household appliances.

[0066] In some embodiments, each detection channel 20 has a detection chamber 23 for accommodating detection reagents, a reaction chamber 22 for accommodating reaction reagents, and a sampling chamber 21 for providing sample liquid to the reaction chamber 22 and the detection chamber 23 of the detection channel. The sampling chambers 21 of each detection channel 20 are independent of each other. That is, each detection channel 20 is sampled independently to allow each detection channel 20 to have a different sample liquid. The sampling chamber 21, reaction chamber 22 and detection chamber 23 of the same detection channel 20 are arranged in sequence along a preset direction (for example, the length direction of the biological detection chip 2) so that the sample liquid in the sampling chamber 21 flows to the reaction chamber 22 and the detection chamber 23 in sequence.

[0067] Furthermore, the sampling chamber 21 is pre-filled with an extraction solution. Once a sample is placed in the sampling chamber 21, it mixes with the extraction solution within the chamber to produce a sample solution. During use, the user simply places the sample into the sampling chamber. The substance to be detected on the sample dissolves in the extraction solution, forming a sample solution of appropriate concentration. This eliminates the tedious manual preparation of the sample solution and improves the user's ease of use when using the bioassay chip 2 for testing. The type and amount of extraction solution in the sampling chambers 21 of different detection channels 20 can be the same or different, as needed.

[0068] In some embodiments, the reaction reagents are pre-installed in the reaction chamber 22 to avoid the trouble of manual addition of the reaction reagents by the user or to avoid the complicated structure caused by the automatic addition of the reaction reagents by the driving mechanism.

[0069] In some embodiments, the reaction reagent can be colloidal gold attached to the inner wall of the reaction chamber 22. The colloidal gold support arranged in this way is stable and not easy to move, so it is not easy to affect the sampling chamber 21 or the detection chamber 23, nor is it easily affected by the reagents in the sampling chamber 21 or the detection chamber 23.

[0070] In some embodiments, the detection reagent is pre-placed in the detection chamber 23 to avoid the troublesome operation caused by the user manually adding the detection reagent or to avoid the complicated structure caused by using a driving mechanism to automatically add the detection reagent.

[0071] In some embodiments, a test paper 60 is provided in the detection chamber 23 , and the detection reagent is integrated on the test paper 60 . At least one side of the detection chamber 23 is open or transparent to facilitate the user to observe the test results on the test paper 60 .

[0072] In some embodiments, the sampling chamber 21, reaction chamber 22, and detection chamber 23 of each detection channel 20 are isolated from each other. Only after the biological detection chip 2 is installed in the chip mounting portion 11, the sampling chamber 21, reaction chamber 22, and detection chamber 23 of each detection channel 20 are connected in sequence with the structural cooperation of the chip mounting portion 11. Therefore, even if the sampling chamber 21, reaction chamber 22, and detection chamber 23 are pre-installed with corresponding types of reagents, regardless of whether the reagents are gaseous, liquid, or solid, the mutual influence between the sampling chamber 21, reaction chamber 22, and detection chamber 23 can be effectively avoided, so that the biological detection chip 2 can be preserved for a long time without becoming ineffective.

[0073] Specifically, at least a portion of the peripheral walls of the sampling chamber 21 and reaction chamber 22 of each detection channel 20 are penetrable walls, so that at least one penetration opening is formed under the action of the piercing structure on the chip mounting portion 11. The chip mounting portion 11 is provided with a first piercing structure 51 having a first through-channel 511 formed therein. The first piercing structure 51 is configured to pierce the penetrable wall 221 of the reaction chamber 22 and the penetrable wall 211 of the sampling chamber 21 of the same detection channel 20 after the biological detection chip 2 is mounted on the chip mounting portion 11, thereby allowing fluid communication between the reaction chamber 22 and the sampling chamber 21 of the same detection channel 20 through the first through-channel 511.

[0074] Furthermore, each detection chamber 23 of the detection channel 20 has a liquid injection port 231 communicating therewith. The chip mounting portion 11 is also provided with a second piercing structure 52 having a second through-channel 521 formed therein. This structure is configured to pierce the permeable wall 222 of the corresponding reaction chamber 22 after the biological detection chip 2 is mounted on the chip mounting portion 11, thereby allowing the reaction chamber 22 to communicate with the liquid injection port 231 of the corresponding detection chamber 23 via the second through-channel 521.

[0075] That is, the first piercing structure 51 can be used to pierce the permeable walls of the sampling chamber 21 and the reaction chamber 22 to establish fluid communication therebetween, and the second piercing structure 52 can be used to pierce the permeable wall of the reaction chamber 22 to establish fluid communication between the reaction chamber 22 and the detection chamber 23. This eliminates the need for complex connecting pipes, simplifies the structure, and allows the sampling chamber 21, reaction chamber 22, and detection chamber 23 of the biological detection chip 2 to be spaced apart, facilitating the long-term storage of the biological detection chip 2 and allowing liquid reagents to be pre-stored in the sampling chamber, reaction chamber, or detection chamber.

[0076] In some embodiments, the chip mounting portion 11 is further provided with a plurality of sample loading structures 70 corresponding one to one with the sampling chamber 21. Each sample loading structure 70 is configured to push the solid sample placed on the outside of the corresponding sampling chamber 21 into the sampling chamber 21 when the biological detection chip 2 is mounted on the chip mounting portion 11, so that the solid sample is immersed in the extract in the sampling chamber 21. The substance to be detected on the solid sample dissolves in the extract to produce a sample liquid. Thus, the sample loading operation can be automatically completed during the installation process of the biological detection chip 2. The user only needs to place the solid sample outside the sampling chamber 21 and directly install the biological detection chip 2. No other operations are required, and there is no need to set other auxiliary sample loading drive mechanisms on the biological detection device 1. This simplifies the structure of the biological detection device 1, reduces its cost, improves the user experience, and makes it more suitable for home use.

[0077] Correspondingly, each sampling chamber 21 is provided with a sampling port 24 for holding a solid sample on its outer side. The sampling ports 24 correspond one-to-one with the positions of the sample loading structures 70 of the biological detection device 1. This allows each sample loading structure 70 to push the solid sample held in the corresponding sampling port 24 into the corresponding sampling chamber 21 when the biological detection chip 2 is installed in the biological detection device 1. The sampling port 24 is separated from the sampling chamber 21 by another permeable wall 212 of the sampling chamber 21. The sample loading structure 70 can penetrate the permeable wall 212 to push the sample into the sampling chamber 21.

[0078] Specifically, the sampling port 24 can be recessed toward the sampling chamber 21 to retain the solid sample therein and prevent it from falling. The multiple sampling ports 24 can be separated from each other to form multiple independent recesses. Alternatively, the multiple sampling ports 24 can be unseparated to form a single, complete recess.

[0079] The chip mounting portion 11 is also provided with connecting posts corresponding to and adjacent to the sample loading structures 70. Branch channels 121 are formed within the connecting posts. After the biological detection chip 2 is mounted on the chip mounting portion 11, the connecting posts penetrate the permeable wall 213 at the top of the corresponding sampling reservoir 21, thereby connecting the branch channels 121 within the connecting posts to the corresponding sampling reservoir 21.

[0080] The following describes in detail a method for controlling a biological detection chip mounted on a biological detection device using the biological detection device. Figure 10 FIG. 1 is a schematic flow chart of a control method for a biological detection device according to an embodiment of the present invention. The control method may include:

[0081] Step S10, receiving a first trigger signal indicating that the biological detection chip 2 has been installed in the chip installation portion 11;

[0082] Step S20, waiting for a first preset time period to allow the substance to be detected on the sample to fully dissolve into the extract in the sampling chamber 21, thereby forming a sample solution of appropriate concentration;

[0083] Step S31 , starting the driving mechanism 30 , causing the sample liquid in the sampling chamber 21 of each detection channel 20 to flow to the reaction chamber 22 of the detection channel through the driving mechanism 30 ;

[0084] Step S32, determining whether the sample liquid flowing into the reaction chamber 22 has reached a preset sample volume; if so, proceeding to step S33; in this step, this can be achieved by detecting the position of the piston. When the piston moves to the preset position, it indicates that the sample liquid flowing into the reaction chamber 22 has reached the preset sample volume;

[0085] Step S33, stopping the driving mechanism 30;

[0086] Step S34: When the driving mechanism 30 stops for a second predetermined time, the driving mechanism 30 is restarted to cause the sample liquid in the reaction chamber 22 of each detection channel 20 to flow to the detection chamber 23 of the detection channel 20;

[0087] Step S40: After waiting for a third preset time, a prompt message is issued to indicate that the detection result has been displayed.

[0088] Furthermore, the control method of the present invention further includes:

[0089] When the second trigger signal for instructing the biological detection chip 2 to be removed from the chip mounting portion 11 is received, the piston of the control driving mechanism 30 is restored to the initial position.

[0090] The present invention also provides a refrigerator. Figure 11is a schematic structural diagram of a refrigerator according to an embodiment of the present application. The refrigerator 100 of the present application comprises the biological detection device 1 involved in any of the above embodiments, so as to integrate the biological detection device 1 on the refrigerator 100. The refrigerator 100 can further comprise the biological detection chip 2 mounted on the biological detection device 1. The refrigerator 100 is used frequently in daily life and is mainly used to store foodstuffs. When the biological detection device 1 is integrated on the refrigerator 100, the user can easily perform the detection operation of the foodstuff sample by using the biological detection device 1.

[0091] Further, the refrigerator 100 further comprises a cabinet 200 and a door body 300. The cabinet 200 defines a storage space therein, and the door body 300 is connected to the cabinet 200 and is used to open and / or close the storage space. The biological detection device 1 is preferably arranged on the door body 300, which is not only convenient to operate, but also does not occupy the original storage space in the cabinet 200 and does not affect the storage capacity of the refrigerator 100 itself.

[0092] Figure 12 is a schematic structural exploded view of a door body according to an embodiment of the present application. In some embodiments, the front side of the door body 300 is provided with a hollow window 301, and the chip mounting portion 11 is exposed to the front side of the door body 300 through the hollow window 301, so as to facilitate the user to install the biological detection chip 2 to implement the detection function without opening the door body 300, thereby ensuring the heat preservation performance of the refrigerator 100 and saving energy consumption.

[0093] Specifically, the door body 300 can comprise a panel 302 for forming the front part thereof, a door lining 303 for forming the rear part thereof, and a foamed heat preservation layer (not shown in the figure) arranged between the panel 302 and the door lining 303. The hollow window 301 is formed in the panel 302. A pre-embedded box 304 is pre-embedded between the panel 302 and the door lining 303 before the foamed heat preservation layer is formed, and the biological detection device 1 is arranged in the pre-embedded box 304. That is, the pre-embedded box 304 is pre-arranged between the panel 302 and the door lining 303 before the door body 300 is foamed, so as to reserve a space for mounting the biological detection device 1 between the panel 302 and the door lining 303.

[0094] Further, the pre-embedded box 304 is attached to the rear surface of the panel 302, and the front side of the pre-embedded box 304 is open and faces the hollow window 301, so as to allow the biological detection device 1 to be mounted into the pre-embedded box 304 from front to back through the hollow window 301, thereby improving the convenience of mounting the biological detection device 1.

[0095] Further, the mounting posture of the biological detection chip 2 in the chip mounting portion 11 is arranged such that each detection channel 20 formed thereby extends in the vertical direction. In this way, the user can easily install the biological detection chip 2, which conforms to the operation habit of the user.

[0096] The refrigerator 100 of the present application is a refrigerator in a broad sense, which not only includes the so-called refrigerator in a narrow sense, but also includes storage devices with refrigeration, freezing or other storage functions, such as refrigerators, freezers, etc.

[0097] Those skilled in the art should also understand that the terms "upper", "lower", "front", "back", "top", "bottom", etc. used to indicate orientation or positional relationships in the embodiments of the present invention are based on the actual usage status of the biological detection device 1 and the refrigerator 100. These terms are only used to facilitate the description and understanding of the technical solution of the present invention, and do not indicate or imply that the device or device referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they should not be understood as limiting the present invention.

[0098] At this point, those skilled in the art will recognize that, although a number of exemplary embodiments of the present invention have been shown and described in detail herein, many other variations or modifications consistent with the principles of the present invention may be directly determined or derived from the disclosure of the present invention without departing from the spirit and scope of the present invention. Therefore, the scope of the present invention should be understood and deemed to cover all such other variations or modifications.

Claims

1. A biological detection device, characterized in that: include: a bracket having a chip mounting portion for mounting at least one biological detection chip, wherein the chip mounting portion is formed with a plurality of fluid interfaces for communicating one-to-one with a plurality of detection channels formed in the at least one biological detection chip; and a driving mechanism, disposed on the support and in communication with each of the fluid interfaces, so that after the at least one biological detection chip is mounted on the chip mounting portion, the driving mechanism is in communication with the plurality of detection channels through the plurality of fluid interfaces; Each of the detection channels comprises a detection chamber for containing a detection reagent, a reaction chamber for containing a reaction reagent, and a sampling chamber for providing a sample liquid to the reaction chamber and the detection chamber; The driving mechanism is configured to cause the sample liquid in each sampling chamber to flow to the corresponding reaction chamber, or to cause the sample liquid in each reaction chamber to flow to the corresponding detection chamber; An extraction liquid is pre-placed in the sampling chamber; the chip mounting portion is also provided with a sample loading structure corresponding to the sampling chamber one by one, and each of the sample loading structures is configured to push the sample placed on the outer side of the corresponding sampling chamber into the sampling chamber when the biological detection chip is mounted on the chip mounting portion, so that the sample is immersed in the extraction liquid in the sampling chamber and produces sample liquid.

2. The biological detection device according to claim 1, characterized in that A connecting channel is formed in the bracket, one end of the connecting channel is connected to the driving mechanism, and the other end has multiple branch channels. The multiple branch channels are respectively connected to the multiple fluid interfaces one by one, so as to simultaneously drive the fluids in the multiple detection channels of the at least one biological detection chip installed in the chip mounting part through the driving mechanism.

3. The biological detection device according to claim 2, characterized in that The driving mechanism is a micro-injection pump, which promotes the flow of fluid in the detection channel by pressing air into the detection channel.

4. The biological detection device according to claim 3, characterized in that The driving mechanism comprises: A driving motor for outputting driving force; a screw rod connected to the drive motor to rotate under the drive of the drive motor; A slider is provided on the screw rod and is threadably connected to the screw rod so as to translate along the screw rod as the screw rod rotates; a syringe, a first end of which is in communication with the connecting channel; and The piston is disposed inside the syringe and fixedly connected to the slider to move inside the syringe driven by the slider, thereby promoting the flow of fluid in the detection channel when the piston moves toward the first end of the syringe.

5. The biological detection device according to claim 4, characterized in that A section of the drive motor connected to the screw rod is fixedly supported on the bracket, and an end of the drive motor facing away from the screw rod and a circumferential side portion of the drive motor are both spaced apart from the bracket.

6. The biological detection device according to claim 4, characterized in that Also includes: A position sensor is used to detect the position of the slider to control the operation of the drive motor according to the position of the slider, thereby controlling the path of fluid flow in the detection channel by controlling the displacement of the piston in the syringe.

7. The biological detection device according to claim 6, characterized in that Also includes: A circuit board is fixed on the bracket, and the position sensor is arranged on the circuit board and electrically connected to the circuit board.

8. The biological detection device according to claim 7, characterized in that: The slider is provided with a bump protruding toward the circuit board, and a through slot for the bump to move therein is provided on one side of the circuit board facing the slider, and the position sensor is adjacently arranged on the outside of the through slot.

9. The biological detection device according to claim 1, characterized in that Also includes: A front cover is provided on the front side of the bracket and has a notch; The chip mounting portion is exposed to the front side of the front cover through the notch.

10. A refrigerator, characterized in that: A biological detection device comprising any one of claims 1-9.

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