A rapid detection device for gynecological diseases

Abstract

The present invention discloses a rapid detection device for gynecological diseases, which relates to the technical field of gynecological disease detection devices, including a base plate for placing a reagent placement box and a waste collection box, and further comprising: a displacement adjustment component, wherein the displacement adjustment component is mounted on the base plate through a bracket, and the displacement adjustment component has a displacement end; a lifting adjustment component, wherein the lifting adjustment component is mounted on the displacement end of the displacement adjustment component, and the lifting adjustment component has a lifting end; a non-contact mixing component, wherein the non-contact mixing component is mounted on the lifting end of the lifting adjustment component, and the non-contact mixing component does not directly contact the diluent in the reagent tube to mix the liquid. The present invention can move the non-contact mixing component to a specified position and perform non-contact mixing processing on the reagent tube through the cooperation of the displacement adjustment component and the lifting adjustment component. This process does not require manual contact and is safe and pollution-free.

Description

Technical Field

[0001] The present invention relates to the technical field of gynecological disease detection devices, and in particular to a gynecological disease rapid detection device. Background Art

[0002] Vaginitis caused by Trichomonas vaginalis infection is a common and frequently occurring gynecological disease. Trichomonas vaginalis primarily parasitizes the female urogenital tract, causing trichomonal vaginitis and urethritis. It is a globally distributed disease that is primarily sexually transmitted. Currently, clinical laboratory detection methods mainly include direct wet mount microscopy, culture, fluorescence quantitative PCR, wet mount, etc.

[0003] Among them, the direct wet mount high-power microscopy method has a low positive diagnosis rate (about 50%) due to the influence of temperature, smear thickness and the level of the examiner, and is prone to missed diagnosis and misdiagnosis.

[0004] The culture method is known as the "gold standard" for the etiological diagnosis of Trichomonas vaginalis due to its high sensitivity and specificity. However, the operation often takes dozens of hours, is complicated and time-consuming, and is usually used to diagnose difficult cases.

[0005] The traditional wet mount method is still used by most hospitals because of its simplicity and low cost, but its sensitivity is low.

[0006] Fluorescent PCR is considered one of the fastest, most accurate, and most efficient methods for detecting Trichomonas vaginalis. It quantifies the DNA of Trichomonas vaginalis, but requires high-quality equipment and is expensive, making rapid detection difficult.

[0007] Therefore, the colloidal gold method is suitable for large-scale inspection because of its speed, convenience and high accuracy. However, in the existing technology, colloidal gold detection is usually carried out by manpower. The existing technology also uses equipment methods for detection, but during the detection process, especially improper handling of the cotton swab, it is easy to cause pollution to the equipment and the environment, which affects the subsequent test results. Summary of the Invention

[0008] The purpose of the present invention is to solve the above problems and to propose a rapid detection device for gynecological diseases.

[0009] In order to achieve the above object, the present invention adopts the following technical solutions:

[0010] A rapid gynecological disease detection device includes a bottom plate for placing a reagent placement box and a waste collection box, and further includes:

[0011] A displacement adjustment component, the displacement adjustment component is mounted on the base plate through a bracket, and the displacement adjustment component has a displacement end;

[0012] A lifting adjustment component, the lifting adjustment component is mounted on the displacement end of the displacement adjustment component, and the lifting adjustment component has a lifting end;

[0013] A non-contact mixing component is installed at the lifting end of the lifting adjustment component, and the non-contact mixing component does not directly contact the diluent in the reagent tube to mix the liquid.

[0014] Optionally, the displacement adjustment assembly includes a fixed frame, a screw rod, a polished rod, a first servo motor and a displacement block, wherein the displacement block is defined as a displacement end of the displacement adjustment assembly;

[0015] The fixing frame is welded to the bracket, the two ends of the polished rod are welded to the fixing frame, the two ends of the screw are rotatably connected to the fixing frame through bearings, the displacement block is threadedly connected to the screw and slidably connected to the polished rod, and the first servo motor is installed on the fixing frame and its output rod is fixed to the screw through a coupling.

[0016] Optionally, the lifting and adjusting component is one of an air cylinder, an oil cylinder, and a push rod motor.

[0017] Optionally, the contactless mixing assembly comprises:

[0018] A casing and a sleeve, wherein the sleeve adopts an annular structure and is arranged at the bottom end of the casing, and an air inlet is arranged on the side wall of the sleeve;

[0019] A small air pump, wherein the small air pump is installed in the casing;

[0020] A hollow rod body, the hollow rod body being rotatably connected to the air inlet pipe of the small air pump via a sealed bearing, the hollow rod body extending to the middle of the housing;

[0021] an adsorption member, the adsorption member being arranged at the end of the hollow rod body and being in communication therewith;

[0022] The rotary drive assembly is arranged on the housing and has an output end, and the output end of the rotary drive assembly is connected to the hollow rod body and drives the hollow rod body to rotate.

[0023] Optionally, the rotation drive assembly consists of a reduction gear set and a second servo motor, the second servo motor is mounted on the housing, the second servo motor is key-connected to the input end of the reduction gear set, and the output end of the reduction gear set is key-connected to the hollow rod body.

[0024] Optionally, the adsorption element adopts a porous spherical structure.

[0025] Optionally, the adsorption part is made of a metal material with a Curie point higher than 200°C, and the outer surface of the shell is provided with a non-contact heating element for traceless treatment of cotton swabs made of polymer materials. The non-contact heating element includes an insulation sleeve, an induction coil and a power supply. The insulation sleeve has an annular space, and an induction coil is provided in the insulation sleeve, and the induction coil is connected to a power supply.

[0026] Optionally, a molten waste liquid filter is provided on the air inlet pipe, and the molten waste liquid filter includes a filter shell and a bend. The air inlet pipe is divided into two and respectively connected to the two ends of the filter shell. The bend is connected to the air inlet pipe at the bottom, and the filter shell is filled with coolant.

[0027] Compared with the prior art, the present invention has the following advantages:

[0028] The present invention can move the non-contact mixing component to a specified position and perform non-contact mixing on the reagent tube through the cooperation of the displacement adjustment component and the lifting adjustment component. This process does not require manual contact and is safe and pollution-free.

[0029] The present invention adopts a non-contact mixing design. The non-contact mixing component 8 does not directly contact the diluent in the reagent tube 3 for mixing. Instead, it mixes the liquid by driving the cotton swab, and finally achieves the mixing of the vaginal extract and the diluent. The use of a non-contact mixing method can avoid two-way contamination of the reagent to the device, or the device to the reagent.

[0030] The present invention adopts an automatic cotton swab processing design. The cotton swab, which is connected to the reagent or device, is adsorbed on the adsorption part by negative pressure and falls into the waste collection box by stopping the negative pressure. During this process, the cotton swab does not need to contact people or third-party objects, which can reduce secondary infection to people or objects.

[0031] In the second embodiment of the present invention, a traceless processing design of the cotton swab is adopted to prevent the cotton swab from secondary pollution to the environment through aerosols and the like. Compared with the cotton swab processing method in the prior art, it is safer and more efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0033] Figure 2 Schematic diagram of the displacement adjustment component structure of the present invention;

[0034] Figure 3 A cross-sectional view of the reagent tube and the non-contact mixing assembly of the present invention;

[0035] Figure 4 Schematic diagram of the structure of the non-contact mixing component in the present invention;

[0036] Figure 5It is a schematic diagram of the structure of the non-contact heating element and the molten waste liquid filtering element in the present invention.

[0037] In the figure: 1 bottom plate, 2 reagent placement box, 3 reagent tube, 4 cotton swab, 5 bracket, 6 displacement adjustment component, 61 fixed frame, 62 screw, 63 polished rod, 64 first servo motor, 65 displacement block, 7 molten waste liquid filter, 71 filter shell, 72 elbow, 8 non-contact mixing component, 81 housing, 82 small air pump, 83 air inlet pipe, 84 hollow rod body, 85 adsorption component, 86 sleeve, 87 air inlet, 88 rotation drive component, 881 reduction gear set, 882 second servo motor, 89 non-contact heating element, 9 lifting adjustment component, 10 waste collection box. DETAILED DESCRIPTION

[0038] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0039] Example 1

[0040] Reference Figure 1-3 A rapid detection device for gynecological diseases includes a base plate 1 for placing a reagent placement box 2 and a waste collection box 10, and the base plate 1 adopts a plate-like structure with a flat upper surface.

[0041] The displacement adjustment component 6 is mounted on the base plate 1 through the bracket 5. The displacement adjustment component 6 has a displacement end, which is as follows:

[0042] The displacement adjustment assembly 6 includes a fixing frame 61 , a screw rod 62 , a polished rod 63 , a first servo motor 64 and a displacement block 65 , wherein the displacement block 65 is defined as a displacement end of the displacement adjustment assembly 6 .

[0043] Fixed frame 61 is welded to bracket 5. Both ends of polished rod 63 are welded to fixed frame 61. Both ends of screw rod 62 are rotatably connected to fixed frame 61 via bearings. Displacement block 65 is threadedly connected to screw rod 62 and slidably connected to polished rod 63. A first servo motor 64 is mounted on fixed frame 61, and its output rod is secured to screw rod 62 via a coupling. First servo motor 64 is controlled by a servo controller.

[0044] The function of the displacement adjustment component 6 is to control the first servo motor 64 through the servo driver, control the rotation of the screw 62 through the first servo motor 64, and drive the displacement block 65 threadedly connected to it to move through the rotation of the screw 62. The setting of the light rod 63 plays a limiting role, so that the displacement block 65 can only achieve linear motion.

[0045] The lifting adjustment component 9 is installed on the displacement end of the displacement adjustment component 6. The lifting adjustment component 9 has a lifting end. In this embodiment, the lifting adjustment component 9 is one of an air cylinder, an oil cylinder, and a push rod motor. The lifting end is the piston rod of the air cylinder, the oil cylinder, or the push rod of the push rod motor.

[0046] The non-contact mixing component 8 is installed at the lifting end of the lifting adjustment component 9 (taking the cylinder as an example, it is installed on the piston rod of the cylinder). The non-contact mixing component 8 does not directly contact the diluent in the reagent tube 3 to mix the liquid. The specific settings are as follows:

[0047] The non-contact mixing assembly 8 includes a housing 81 , a small air pump 82 , an air inlet pipe 83 , a hollow rod 84 , an adsorption member 85 , a casing 86 , an air inlet 87 and a rotation drive assembly 88 .

[0048] The casing 86 has an annular structure and is disposed at the bottom of the housing 81. An air inlet 87 is disposed on the side wall of the casing 86. The air inlet 87 can be a circular through hole for connecting the inside and outside of the casing 86, thereby balancing the internal and external air pressures.

[0049] A small air pump 82 is installed in the housing 81 , and is used to provide negative pressure through the air inlet pipe 83 .

[0050] The hollow rod body 84 is rotatably connected to the air inlet pipe 83 of the small air pump 82 through a sealed bearing. The hollow rod body 84 extends to the middle of the shell 86. Through the rotational connection of the bearing, the hollow body 84 can be rotatably connected while being connected to the air inlet pipe 83, so that the rotational movement of the cotton swab 4 can be driven when the negative pressure adsorption is finally achieved through the rotational connection of the hollow rod body 84.

[0051] The adsorption member 85 is disposed at the end of the hollow rod 84 and is in communication therewith. The adsorption member 85 is in a porous spherical structure. Figure 3 shown.

[0052] The rotation drive assembly 88 is disposed on the housing 81 and has an output end. The output end of the rotation drive assembly 88 is connected to the hollow rod 84 and drives the hollow rod 84 to rotate.

[0053] Reference Figure 3 As shown, when the adsorption part 85 rotates, it can drive the cotton swab 4 adsorbed thereon to rotate. Through the rotation of the cotton swab 4, the diluent in the reagent tube 3 is stirred by the cotton swab 4 for about 30 seconds, thereby mixing the vaginal extract and the diluent.

[0054] The testing process is as follows: First, the patient uses a cotton swab to collect secretions from the posterior vaginal fornix and vaginal wall, then moves it into reagent tube 3, contacts it with approximately 1ML of diluent in reagent tube 3, and finally rotates and mixes it for about 30s-40s. Finally, the cotton swab is removed and discarded and the test strip is inserted for testing.

[0055] During use, the displacement adjustment component 6 can drive the lifting adjustment component 9 to perform horizontal displacement movement. After the lifting adjustment component 9 moves to the specified position, the displacement adjustment component 6 is closed, and the lifting adjustment component 9 drives the non-contact mixing component to move downward, and the shell 86 is put on the reagent tube 3. Finally, the small air pump 82 and the rotation drive component 88 are turned on to capture the cotton swab 4 and mix the vaginal extract with the diluent through the cotton swab 4. The above steps can be controlled by PLC programming.

[0056] Example 2

[0057] Reference Figure 4 In this embodiment, the adsorption member 85 is made of a metal material with a Curie point higher than 200°C, and the hollow pipe 84 should also be made of the same material. For example, the Curie point of cobalt-based amorphous alloy is 205°C, the Curie point of manganese-zinc ferrite is 215°C, and the Curie point of iron-based amorphous alloy is 370°C. Alternatively, iron with a higher temperature is used, and its Curie point is 769°C. When the temperature reaches the Curie point, the material loses its magnetism. Therefore, the actual maximum temperature that can be heated is not higher than the Curie point, and the temperature should not be too high.

[0058] In this embodiment, the medical cotton swabs are polymer cotton swabs and degradable cotton swabs. For example, the common medical PP material has a melting point of 167°C. Degradable cotton swabs made of PLA can also be used, and its melting point is 155-185°C. Therefore, considering all factors, a metal material with a Curie point of over 200°C can be used. If a PVA head is used, its melting point is 230-240°C, then a material with a Curie point of more than 250°C needs to be used.

[0059] A non-contact heating element 89 is provided on the outer surface of the shell 86. The non-contact heating element 89 includes an insulating sleeve 891, an induction coil 892 and a power supply. The insulating sleeve 891 has an annular space, and an induction coil 892 is provided in the insulating sleeve 891. The induction coil 892 is connected to a power supply.

[0060] The power supply can adopt a high-frequency power supply of 300W or above. According to the principle of electromagnetic induction, when the current of the high-frequency power supply passes through the induction coil 892, a magnetic field will be generated in the induction coil 892. Under the action of electromagnetic induction, the metal adsorption part 85 will generate induced current and induced electromotive force on its surface, and will be heated to a temperature close to the Curie point under the action of the induced current. The heating efficiency can be increased by increasing the power of the power supply, so that the cotton swab 4 (PP material) can be melted and adsorbed into the adsorption part 85 through negative pressure, and the viruses, bacteria, etc. on the cotton swab 4 will also be killed under high temperature.

[0061] This embodiment also includes a molten waste liquid filter 7, which is provided on the air inlet pipe 83. The molten waste liquid filter 7 includes a filter shell 71 and a bend 72. The air inlet pipe 83 is divided into two and is respectively connected to the two ends of the filter shell 71. The bend 72 is connected to the air inlet pipe 83 at the bottom. The filter shell 71 is filled with coolant.

[0062] The function of the molten waste liquid filter element 7 is that, through the negative pressure of the small air pump 82, the molten liquid is sucked into the elbow 72 through the hollow pipe 84, and finally falls into the liquid in the filter housing 71 under the action of gravity to cool and solidify. After a period of time, the filter housing 71 can be opened for processing.

[0063] The cotton swab processing in this embodiment can be traceless and non-toxic, and reduce the processing workload of subsequent staff, especially preventing the cotton swab from secondary pollution to the environment through aerosols and other means. Compared with the cotton swab processing method in Example 1 or the prior art, it is safer and more efficient.

[0064] The above description is only a preferred specific embodiment of the present invention. It is impossible to list all the embodiments here, but the protection scope of the present invention is not limited to this. Any technician familiar with this technical field can make equivalent replacements or changes based on the technical solutions and inventive concepts of the present invention within the technical scope disclosed by the present invention, and they should be covered by the protection scope of the present invention.

Claims

1. A rapid detection device for gynecological diseases, comprising a bottom plate (1) for placing a reagent placement box (2) and a waste collection box (10), characterized in that: Also includes: A displacement adjustment component (6), the displacement adjustment component (6) is mounted on the base plate (1) via a bracket (5), and the displacement adjustment component (6) has a displacement end; A lifting adjustment component (9), the lifting adjustment component (9) is mounted on the displacement end of the displacement adjustment component (6), and the lifting adjustment component (9) has a lifting end; A non-contact mixing component (8), the non-contact mixing component (8) being mounted on the lifting end of the lifting adjustment component (9), and the non-contact mixing component (8) mixing the liquid without direct contact with the diluent in the reagent tube (3); The non-contact mixing assembly (8) comprises: A casing (81) and a sleeve (86), wherein the sleeve (86) has an annular structure and is disposed at the bottom end of the casing (81), and an air inlet (87) is disposed on a side wall of the sleeve (86); A small air pump (82), wherein the small air pump (82) is installed in the housing (81); A hollow rod body (84), the hollow rod body (84) being rotatably connected to the air inlet pipe (83) of the small air pump (82) via a sealed bearing, the hollow rod body (84) extending to the middle of the casing (86); An adsorption member (85), the adsorption member (85) is a porous spherical structure, made of a metal material with a Curie point higher than 200°C, and is disposed at the end of the hollow rod (84) and communicated with the same; A rotary drive assembly (88), the rotary drive assembly (88) being disposed on the housing (81), the rotary drive assembly (88) having an output end, and the output end of the rotary drive assembly (88) being connected to the hollow rod body (84) and driving the hollow rod body (84) to rotate; A non-contact heating element (89) is provided on the outer surface of the housing (86) and is used for traceless treatment of a cotton swab (4) made of a polymer material. The non-contact heating element (89) comprises a heat-insulating sleeve (891), an induction coil (892) and a power supply. The heat-insulating sleeve (891) has an annular space therein, and an induction coil (892) is provided in the heat-insulating sleeve (891). The induction coil (892) is connected to a power supply.

2. A rapid gynecological disease detection device according to claim 1, characterized in that: The displacement adjustment component (6) includes a fixed frame (61), a screw rod (62), a polished rod (63), a first servo motor (64) and a displacement block (65), wherein the displacement block (65) is defined as a displacement end of the displacement adjustment component (6); The fixing frame (61) is welded to the bracket (5), both ends of the polished rod (63) are welded to the fixing frame (61), both ends of the screw rod (62) are rotatably connected to the fixing frame (61) through bearings, the displacement block (65) is threadedly connected to the screw rod (62) and slidably connected to the polished rod (63), and the first servo motor (64) is mounted on the fixing frame (61) and its output rod is fixed to the screw rod (62) through a coupling.

3. A rapid gynecological disease detection device according to claim 1, characterized in that: The lifting and adjusting component (9) is one of an air cylinder, an oil cylinder, and a push rod motor.

4. A rapid gynecological disease detection device according to claim 1, characterized in that: The rotary drive assembly (88) is composed of a reduction gear set (881) and a second servo motor (882). The second servo motor (882) is mounted on the housing (81). The second servo motor (882) is key-connected to the input end of the reduction gear set (881). The output end of the reduction gear set (881) is key-connected to the hollow rod body (84).

5. The rapid detection device for gynecological diseases according to claim 1, characterized in that: A molten waste liquid filter element (7) is provided on the air inlet pipe (83), and the molten waste liquid filter element (7) includes a filter shell (71) and a bend (72). The air inlet pipe (83) is divided into two and is respectively connected to the two ends of the filter shell (71). The bend (72) is connected to the air inlet pipe (83) at the bottom. The filter shell (71) is filled with coolant.

Images