Gas path device for a sample analyzer

By designing the gas path device of the sample analyzer and using the positive or negative pressure control of the gas source mechanism and pressure tube, the problem of unstable storage state of the sampling needle during the transfer process was solved, realizing the stability of liquid storage and the diversification of functions.

CN114636838BActive Publication Date: 2025-12-12SHENZHEN DYMIND BIOTECH
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Patent Information

Application Number
CN202011488528.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-12-16
Publication Date
2025-12-12
Estimated Expiration
2040-12-16

AI Technical Summary

Technical Problem

In the existing technology, the storage state of the sampling needle is unstable and its function is limited during sample transfer.

Method used

A gas path device for a sample analyzer was designed, including a gas source mechanism, a pipetting mechanism, and a pressure tube. The gas source mechanism generates positive or negative pressure, the pipetting mechanism is connected to the gas source mechanism to draw or release gas or liquid, and the pressure tube is connected to the gas source mechanism to provide positive or negative pressure, thereby achieving stable storage of liquid and diversified functions.

Benefits of technology

This invention enables the pipetting mechanism to maintain a stable liquid storage state during the transfer process after liquid is drawn in, and expands the functional applicability of the gas circuit device.

✦ Generated by Eureka AI based on patent content.

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    Figure CN114636838B_ABST
Patent Text Reader

Abstract

The application discloses a gas path device of a sample analyzer, which comprises a gas source mechanism, a pipetting mechanism and a pressure pipe. The gas source mechanism is used for generating positive pressure or negative pressure. The pipetting mechanism is communicated with the gas source mechanism and is used for sucking or releasing gas or liquid under the action of the positive pressure or the negative pressure of the gas source mechanism. The pressure pipe is communicated with the gas source mechanism and is used for providing positive pressure or negative pressure to an external device under the action of the positive pressure or the negative pressure of the gas source mechanism. By providing negative pressure to the pipetting mechanism through the gas source mechanism, the storage state of liquid can be kept stable during the transfer process of the pipetting mechanism after sucking the liquid. By providing positive pressure or negative pressure to the external device through the pressure pipe, the function of the gas path device can be more diversified, and the application range is wider.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, in particular to a gas circuit device of a sample analyzer. BACKGROUND

[0002] In the current medical equipment, when using a test product to diagnose the physical condition of a patient, the material to be detected is usually sampled first, such as blood sampling, and after obtaining the sample, the sample is sucked and transferred by a suction mechanism and a pipetting mechanism to react with the test product.

[0003] The present application relates to the technical field of medical equipment, in particular to a gas circuit device of a sample analyzer. SUMMARY

[0004] The present application provides a gas circuit device of a sample analyzer to solve the technical problems of unstable storage state and single function of the sample in the transfer process by the sample suction needle and other mechanisms in the prior art.

[0005] To solve the above technical problems, one technical solution of the present application is to provide a gas circuit device of a sample analyzer, comprising:

[0006] A gas source mechanism for generating positive pressure or negative pressure;

[0007] A pipetting mechanism in communication with the gas source mechanism for sucking or releasing gas or liquid under the action of the positive pressure or negative pressure of the gas source mechanism;

[0008] A pressure pipe in communication with the gas source mechanism for providing positive pressure or negative pressure to an external device under the action of the positive pressure or negative pressure of the gas source mechanism.

[0009] In one embodiment, the gas source mechanism includes a first syringe and a second syringe, the first syringe is in communication with the pipetting mechanism for providing positive pressure or negative pressure to the pipetting mechanism, and the second syringe is in communication with the pressure pipe for providing positive pressure or negative pressure to the pressure pipe.

[0010] In one embodiment, the gas circuit device further includes a driver and a substrate, the first syringe includes a first syringe tube and a first piston, the first syringe tube is formed with a first accommodating cavity, the first piston is arranged in the first accommodating cavity and connected with the substrate, the second syringe includes a second syringe tube and a second piston, the second syringe tube is formed with a second accommodating cavity, the second piston is arranged in the second accommodating cavity and connected with the substrate, and the driver is used to drive the substrate to move along the axial direction of the first syringe tube.

[0011] In one embodiment, the gas path device further comprises a first electronic valve, the first electronic valve is formed with a first inlet, a first outlet and a second outlet, the first inlet is communicated with the second syringe, the first outlet is communicated with the first syringe, and the second outlet is communicated with the pressure tube.

[0012] In one embodiment, the gas path device further comprises a pressure chamber mechanism, a second electronic valve and a third electronic valve, the pressure chamber mechanism is communicated with the gas source mechanism and the pressure tube respectively, the second electronic valve is arranged between the pressure chamber mechanism and the gas source mechanism, and the third electronic valve is arranged between the pressure chamber mechanism and the pressure tube, the pressure chamber mechanism is used for storing the positive pressure or negative pressure generated by the gas source mechanism.

[0013] In one embodiment, the pressure chamber mechanism comprises at least two pressure chambers, the at least two pressure chambers comprise a first pressure chamber and a second pressure chamber, the first pressure chamber is communicated with the gas source mechanism and the pressure tube respectively, and the second pressure chamber is communicated with the first pressure chamber.

[0014] In one embodiment, the pressure chamber mechanism further comprises a pressure chamber stabilizer, the pressure chamber stabilizer is communicated with the first pressure chamber or the second pressure chamber.

[0015] In one embodiment, the second electronic valve is a three-way valve, the second electronic valve is formed with a second inlet, a third outlet and a fourth outlet, the second inlet is communicated with the gas source mechanism, the third outlet is communicated with the pressure chamber mechanism, and the fourth outlet is communicated with external air or external equipment, and the third electronic valve is a one-way valve.

[0016] In one embodiment, the gas path device further comprises an air filter, the air filter is communicated with the fourth outlet.

[0017] In one embodiment, the liquid transfer mechanism comprises a liquid storage box for storing the liquid to be sucked, and the gas path device further comprises a fourth electronic valve, the fourth electronic valve is arranged between the liquid storage box and the first syringe.

[0018] The gas path device of the sample analyzer of the present invention includes a gas source mechanism, a pipetting mechanism, and a pressure tube. The gas source mechanism is used to generate positive or negative pressure. The pipetting mechanism is connected to the gas source mechanism and is used to draw or release gas or liquid under the action of the positive or negative pressure of the gas source mechanism. The pressure tube is connected to the gas source mechanism and is used to provide positive or negative pressure to external devices under the action of the positive or negative pressure of the gas source mechanism. By providing negative pressure to the pipetting mechanism through the gas source mechanism, the storage state of the liquid can be kept stable during the transfer process after the liquid is drawn. Furthermore, by providing positive or negative pressure to external devices through the pressure tube, the gas path device can be made more versatile and have a wider range of applications. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort, wherein:

[0020] Figure 1 This is a schematic diagram of the gas path device of the sample analyzer of the present invention. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0022] The terms "first" and "second" in this application are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly defined. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion. For example, a process, method, system, product, or device that includes a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products, or devices. The term "and / or" is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A alone, A and B simultaneously, or B alone. Additionally, the character " / " in this document generally indicates that the preceding and following related objects are in an "or" relationship.

[0023] With reference to Figure 1 The gas circuit device 10 of the sample analyzer of the present application includes a gas source mechanism 100, a pipetting mechanism 200, and a pressure pipe 300. The gas source mechanism 100 is configured to generate positive pressure or negative pressure. The pipetting mechanism 200 is in communication with the gas source mechanism 100 and is configured to suck or release gas or liquid under the action of the positive pressure or negative pressure of the gas source mechanism 100. The pressure pipe 300 is in communication with the gas source mechanism 100 and is configured to provide positive pressure or negative pressure to an external device (not shown in the figure) under the action of the positive pressure or negative pressure of the gas source mechanism 100. By providing negative pressure to the pipetting mechanism 200 through the gas source mechanism 100, the storage state of the liquid during the transfer process after the pipetting mechanism 200 sucks the liquid can be kept stable. By providing positive pressure or negative pressure to the external device through the pressure pipe 300, the function of the gas circuit device 10 can be more diversified, and the application range can be wider.

[0024] In this embodiment, the gas source mechanism 100 can include a first syringe 110 and a second syringe 120. The first syringe 110 is in communication with the pipetting mechanism 200 and is configured to provide positive pressure or negative pressure to the pipetting mechanism 200. The second syringe 120 is in communication with the pressure pipe 300 and is configured to provide positive pressure or negative pressure to the pressure pipe 300. The positive pressure or negative pressure provided to the pipetting mechanism 200 and the pressure pipe 300 can be controlled respectively, thereby improving the pipetting precision of the pipetting mechanism 200 and improving the flexibility of the gas circuit device 10.

[0025] In this embodiment, the capacity of the first syringe 110 can be 80ul to 120ul, and the capacity of the second syringe 120 can be 8ml to 12ml. Since the capacity of the first syringe 110 is smaller, the precision of each extraction or release is higher, thereby further improving the pipetting precision of the pipetting mechanism 200.

[0026] In other embodiments, the capacities of the first syringe 110 and the second syringe 120 can also be adjusted according to actual needs, which are not limited herein.

[0027] In other embodiments, the gas source mechanism 100 can also include at least one of a syringe, a gas pump, a gas cylinder, and a plunger pump, etc.

[0028] In the embodiment, the gas path device 10 further comprises a driver 130 and a base plate 140, the first injector 110 comprises a first injector tube 111 and a first piston 112, the first injector tube 111 is formed with a first accommodating cavity, the first piston 112 is arranged in the first accommodating cavity and connected with the base plate 140, the second injector 120 comprises a second injector tube 121 and a second piston 122, the second injector tube 121 is formed with a second accommodating cavity, the second piston 122 is arranged in the second accommodating cavity and connected with the base plate 140, the driver 130 is used to drive the base plate 140 to move along the axial direction of the first injector tube 111 to perform suction or release. By connecting the first piston 112 and the second piston 122 to the base plate 140, the driving of the first piston 112 and the second piston 122 can be realized by using only one driver 130, so that the structure of the gas path device 10 is simpler, the occupied space is smaller, and the cost is saved.

[0029] In other embodiments, suction or release can also be realized by driving the first injector tube 111 and the second injector tube 121, which is not limited here.

[0030] In other embodiments, the first injector 110 and the second injector 120 can also be driven by two drivers respectively, which can make the control more flexible, which is not limited here.

[0031] In the embodiment, the gas path device 10 can further comprise a first electronic valve 150, the first electronic valve 150 is formed with a first inlet I1, a first outlet O11 and a second outlet O12, the first inlet I1 communicates with the second injector 120, the first outlet O11 communicates with the first injector 110, and the second outlet O12 communicates with the pressure tube 300, so that the first injector 110 can also provide positive pressure or negative pressure to the pipetting mechanism 200, so that the pipetting mechanism 200 can suck or release a larger amount of gas or liquid, and the application range of the gas path device 10 is wider.

[0032] In the embodiment, the gas path device 10 can further comprise a controller (not shown in the figure), the controller is used to control the first outlet O11 of the first electronic valve 150 to remain closed when the required amount of liquid is less than or equal to the accommodation of the first injector 110, control the pipetting mechanism 200 to move above the sample container, and then control the driver 130 to drive the base plate 140 to move downward along the axial direction of the first injector tube 111 to suck the liquid in the sample container, and then control the pipetting mechanism 200 to move above the target pool, and control the driver 130 to drive the base plate 140 to move upward along the axial direction of the first injector tube 111 to release the liquid into the target pool.

[0033] The controller is further configured to, when the required amount of liquid to be taken is greater than the capacity of the first syringe 110, control the first outlet O11 of the first electronic valve 150 to open, then control the pipetting mechanism 200 to move above the sample container, control the driver 130 to drive the base plate 140 to move downward along the axis of the first syringe 111 to take the liquid in the sample container, and then control the first outlet O11 to close until the pipetting mechanism 200 moves above the target pool, so that the storage state of the liquid during the movement of the pipetting mechanism 200 is more stable, and then the controller controls the first outlet O11 to open and controls the driver 130 to drive the base plate 140 to move upward along the axis of the first syringe 111 to release the liquid into the target pool, and the above process is repeated until the amount of liquid taken reaches the target amount.

[0034] In this embodiment, the controller can also control the driver 130 to drive the base plate 140 to move downward along the axis of the first syringe 111 to take the external air through the pipetting mechanism 200 before taking the liquid, thereby eliminating the back error, reducing the error, and further improving the capacity accuracy of the taken liquid.

[0035] In this embodiment, the pipetting mechanism 200 includes a liquid storage box 210 and a fourth electronic valve 220. The liquid storage box 210 is used to store the taken liquid for convenient transportation and transfer. The fourth electronic valve 220 is arranged between the liquid storage box 210 and the first syringe 110, and can be used to control the on-off between the liquid storage box 210 and the first syringe 110, thereby making the storage state of the liquid storage box 210 more stable.

[0036] In this embodiment, the gas circuit device 10 further includes a pressure chamber mechanism 400, a second electronic valve 410, and a third electronic valve 420. The pressure chamber mechanism 400 is in communication with the gas source mechanism 100 and the pressure pipe 300, respectively. The second electronic valve 410 is arranged between the pressure chamber mechanism 400 and the gas source mechanism 100, and the third electronic valve 420 is arranged between the pressure chamber mechanism 400 and the pressure pipe 300. The pressure chamber mechanism 400 is used to store the positive pressure or negative pressure generated by the gas source mechanism 100, so that when it is required to provide positive pressure or negative pressure to external equipment, sufficient positive pressure or negative pressure can be quickly provided, and the reliability is higher.

[0037] In the embodiment, the pressure chamber mechanism 400 comprises at least two pressure chambers, including a first pressure chamber 430 and a second pressure chamber 440, the first pressure chamber 430 is in communication with the air source mechanism 100 and the pressure pipe 300 respectively, and the second pressure chamber 440 is in communication with the first pressure chamber 430. Compared with the case of using only one pressure chamber with large capacity to provide positive pressure or negative pressure to the external device, the pressure value in the pressure chamber can only be stabilized at a certain value. In the embodiment, by setting two communicating pressure chambers, the pressure values in the two pressure chambers can be controlled within a certain range when providing positive pressure or negative pressure to the external device, and the application range is wider.

[0038] In the embodiment, the pressure chamber mechanism 400 further comprises a pressure chamber pressure stabilizer 450, which is in communication with the first pressure chamber 430 or the second pressure chamber 440, and is used to keep the pressure in the first pressure chamber 430 and the second pressure chamber 440 within a bearable range.

[0039] In the embodiment, the pressure chamber pressure stabilizer 450 can be a pressure sensor, which is used to detect the pressure value in the first pressure chamber 430 or the second pressure chamber 440, and can monitor the pressure value in the first pressure chamber 430 or the second pressure chamber 440, so as to perform corresponding operations to protect the first pressure chamber 430 or the second pressure chamber 440 when the pressure value in the first pressure chamber 430 or the second pressure chamber 440 is too high or too low. And by detecting the pressure value, the working condition of the air path device 10 can be obtained to facilitate corresponding control operations according to different conditions.

[0040] In other embodiments, the pressure chamber pressure stabilizer 450 can also be a pressure valve or other forms of pressure stabilizing mechanism, which is not limited here.

[0041] In the embodiment, the second electronic valve 410 is a three-way valve, and the second electronic valve 410 is formed with a second inlet I2, a third outlet O21 and a fourth outlet O22. The second inlet I2 is in communication with the air source mechanism 100, the third outlet O21 is in communication with the pressure chamber mechanism 400, and the fourth outlet O22 is in communication with the external air or the external device.

[0042] In the embodiment, the air path device 10 further comprises an air filter 500, which is in communication with the fourth outlet O22 and is used to filter and purify the air flowing through the second electronic valve 410.

[0043] In the embodiment, the third electronic valve 420 is a one-way valve, which is used to control the one-way movement of air from the pressure pipe 300 to the pressure chamber mechanism 400, and can avoid the external air connected by the external device from flowing back to the pressure chamber mechanism 400.

[0044] In the embodiment, the controller can further be configured to control the second outlet O12 of the first electronic valve 150 to be opened, the second inlet I2 and the third outlet O21 of the second electronic valve 410 to be opened, and then control the driver 130 to drive the base plate 140 to move downward along the axial direction of the first injection tube 111 to form negative pressure in the first pressure chamber 430 and the second pressure chamber 440, control the second inlet I2 of the second electronic valve 410 to be closed after the second syringe 120 reaches the maximum range, and then control the driver 130 to drive the base plate 140 to move upward along the axial direction of the first injection tube 111 to reset the second syringe 120, and then control the second inlet I2 and the third outlet O21 of the second electronic valve 410 to be opened again, control the driver 130 to drive the base plate 140 to move downward along the axial direction of the first injection tube 111 to increase the negative pressure in the first pressure chamber 430 and the second pressure chamber 440, and repeat the above process until the negative pressure in the first pressure chamber 430 and the second pressure chamber 440 reaches a target value, and then control the second electronic valve 410 to be closed to complete the negative pressure storage of the pressure chamber mechanism 400.

[0045] When it is required to provide negative pressure to an external device, the pressure tube is communicated with the external device, and the controller controls the third electronic valve 420 to be opened to provide negative pressure to the external device.

[0046] The above description is only an embodiment of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation, or direct or indirect application in other related technical fields, which is based on the content of the specification and drawings of the present application, is also included in the patent protection scope of the present application.

Claims

1. A gas path device of a sample analyzer, characterized by, The gas path device comprises: a gas source mechanism for generating positive pressure or negative pressure; a pipetting mechanism in communication with the gas source mechanism for sucking or releasing gas or liquid under the action of the positive pressure or negative pressure of the gas source mechanism; a pressure pipe in communication with the gas source mechanism for providing positive pressure or negative pressure to an external device under the action of the positive pressure or negative pressure of the gas source mechanism; wherein the gas path device further comprises a pressure chamber mechanism, a second electronic valve and a third electronic valve, the pressure chamber mechanism is in communication with the gas source mechanism and the pressure pipe respectively, the second electronic valve is arranged between the pressure chamber mechanism and the gas source mechanism, the third electronic valve is arranged between the pressure chamber mechanism and the pressure pipe, and the pressure chamber mechanism is used for storing the positive pressure or negative pressure generated by the gas source mechanism; the pressure chamber mechanism comprises at least two pressure chambers, including a first pressure chamber and a second pressure chamber, the first pressure chamber is in communication with the gas source mechanism and the pressure pipe respectively, and the second pressure chamber is in communication with the first pressure chamber.

2. The air path device according to claim 1, characterized by, The gas source mechanism comprises a first syringe and a second syringe, the first syringe is in communication with the pipetting mechanism for providing positive pressure or negative pressure to the pipetting mechanism, and the second syringe is in communication with the pressure pipe for providing positive pressure or negative pressure to the pressure pipe.

3. The air path device according to claim 2, wherein The gas path device further comprises a driver and a substrate, the first syringe comprises a first syringe tube and a first piston, the first syringe tube is formed with a first accommodating cavity, the first piston is arranged in the first accommodating cavity and connected with the substrate, the second syringe comprises a second syringe tube and a second piston, the second syringe tube is formed with a second accommodating cavity, the second piston is arranged in the second accommodating cavity and connected with the substrate, and the driver is used for driving the substrate to move along the axial direction of the first syringe tube.

4. The air path device according to claim 2, wherein The gas path device further comprises a first electronic valve, the first electronic valve is formed with a first inlet, a first outlet and a second outlet, the first inlet is in communication with the second syringe, the first outlet is in communication with the first syringe, and the second outlet is in communication with the pressure pipe.

5. The air path device according to claim 1, wherein The pressure chamber mechanism further comprises a pressure chamber stabilizer, the pressure chamber stabilizer is in communication with the first pressure chamber or the second pressure chamber.

6. The air path device according to claim 1, wherein The second electronic valve is a three-way valve, the second electronic valve is formed with a second inlet, a third outlet and a fourth outlet, the second inlet is in communication with the gas source mechanism, the third outlet is in communication with the pressure chamber mechanism, the fourth outlet is in communication with external air or an external device, and the third electronic valve is a one-way valve.

7. The air path device according to claim 6, wherein The gas path device further comprises an air filter, the air filter is in communication with the fourth outlet.

8. The air path device according to claim 2, wherein The pipetting mechanism comprises a liquid storage box for storing the sucked liquid, and the gas path device further comprises a fourth electronic valve, the fourth electronic valve is arranged between the liquid storage box and the first syringe.

Citation Information

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