A driving device for drug sustained-release infusion

Through the Peltier element and memory metal strip drive device, the problem of high cost of precision motors in insulin pumps is solved, drug sustained release infusion and speed regulation is realized, and equipment costs are reduced.

CN114652918BActive Publication Date: 2025-07-11MIRROR LIFE (SUZHOU) TECH CO LTD
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Patent Information

Application Number
CN202210370173.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-04-08
Publication Date
2025-07-11
Estimated Expiration
2042-04-08

AI Technical Summary

Technical Problem

The precision micro motors used in existing insulin pumps are costly, increasing the cost of equipment development and user use, and it is difficult to achieve flexible regulation of drug infusion speed.

Method used

The drive device composed of Peltier elements and memory metal strips is used to realize drug infusion through refrigeration and heating. Using the thermal effect of Peltier elements and the deformation characteristics of memory metal, the driving gears and screws push the piston to achieve sustained release infusion of drugs.

Benefits of technology

The function of drug sustained release infusion is realized, without the need for a precision micro motor, which reduces costs and can adjust the infusion speed according to needs to meet different needs.

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Abstract

The present invention relates to a driving device for drug sustained-release infusion, which includes a first lead screw, a first gear, a first fixed pulley, a first driving strip, a first lever, a first Peltier element and a controller. The first lead screw is movably installed on the infusion device and connected to a first piston; the first gear is rotatably installed on the infusion device and is provided with a first spiral groove connected to the first lead screw; the first fixed pulley is located on both sides of the first gear; the first driving strip is sleeved on the first fixed pulley; the first lever is fixed on the first driving strip and is located on one side of the first gear; the first Peltier element is fixed on the infusion device and connected to both ends of the first driving strip, and the controller is connected to the first Peltier element for enabling the first Peltier element to contract the first driving strip through refrigeration and heating, and pushing the first gear to rotate through the first lever, so that the first lead screw and the first piston move axially. This device can achieve sustained-release infusion without a precision micro motor.
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Description

Technical Field

[0001] The present invention relates to a driving device for a medical device, in particular to a driving device for drug sustained-release infusion. Background Art

[0002] Many target populations require long-term and small-dose drug infusion for the continuous treatment of chronic diseases. For example, more and more diabetic patients use insulin pumps to replace traditional insulin injection. The basic function of an insulin pump is to simulate the secretion function of the pancreas and maximize the physiological secretion pattern of insulin, so as to achieve a better insulin treatment method for blood glucose control. Rational use of an insulin pump can simulate the basal secretion of physiological insulin, make blood glucose stable and normal, more perfect, and can well control the level of glycated hemoglobin (HbA1c) and reduce the risk rate of complications.

[0003] Insulin pump treatment uses an insulin input device controlled by artificial intelligence. Generally, it mainly consists of a driving device, a drug reservoir, a battery, an infusion catheter system, an electronic control module, and a user interaction module. Its principle is that after the syringe is loaded into the pump, the guiding needle at the front end of the connected infusion tube is inserted into the subcutaneous tissue of the patient (usually the abdominal wall) with a needle injector, and then the piston of the small syringe is pushed by the driving device to infuse insulin into the body. Currently, the core of the driving device is often a micro and precise motor, which can achieve high-precision motion control and then be converted into precise infusion of drug liquid. The micro motor drives the lead screw to inject insulin, and the micro motor is expensive and needs to be imported, increasing the development cost of the equipment and the use cost of users. Summary of the Invention

[0004] To solve the above problems, the present invention provides a driving device for drug sustained-release infusion that does not require a precise micro motor and has a low cost. The specific technical solution is as follows:

[0005] A driving device for drug sustained-release infusion, comprising: a first lead screw, the first lead screw is movably installed on the infusion device and connected to a first piston; a first gear, the first gear is rotatably installed on the infusion device, a first spiral groove is provided at the center of the first gear, and the first lead screw is installed in the first spiral groove; a plurality of first fixed pulleys, the first fixed pulleys are installed on the infusion device and are located on both sides of the first gear; a first driving strip, the first driving strip is a metal strip, and the first driving strip is sleeved on the first fixed pulley; a first dial rod, the first dial rod is fixed on the first driving strip and is located on one side of the first gear; a first Peltier element, the first Peltier element is fixed on the infusion device and is located below the first gear, and the two ends of the first driving strip are respectively fixed on the upper end plate and the lower end plate of the first Peltier element; and a controller, the controller is connected to the first Peltier element and is used to make the first Peltier element rapidly deform the first driving strip through refrigeration and heating, and push the first gear to rotate through the first dial rod, and the first gear pushes the first lead screw and the first piston to move axially.

[0006] Preferably, the first driving strip is a shape memory metal strip.

[0007] Further, an insulating and heat-insulating seat is further included. The first driving strip includes a first upper driving strip and a first lower driving strip. One ends of the first upper driving strip and the first lower driving strip are respectively fixed on both sides of the insulating and heat-insulating seat, and the other ends of the first upper driving strip and the first lower driving strip are respectively fixed on the upper end plate and the lower end plate of the first Peltier element. The first dial rod is fixed on the first lower driving strip;

[0008] Both the first upper driving strip and the first lower driving strip are sleeved on the first fixed pulley.

[0009] Preferably, it further includes: a second lead screw movably installed on the infusion device and connected to the second piston; a second gear rotatably installed on the infusion device, located on one side of the first gear and arranged staggeredly with the first gear, with a second helical groove provided at the center of the second gear, and the second lead screw is installed in the second helical groove; a second lever fixed on the first drive bar and located on one side of the second gear; a plurality of second fixed pulleys installed on the infusion device and located between the first gear and the second gear; a second drive bar which is a metal bar, sleeved on the second fixed pulleys and fixedly connected to the first drive bar; and a second Peltier element fixed on the infusion device, perpendicular to the first Peltier element, with both ends of the second drive bar respectively fixed on the upper end plate and the lower end plate of the second Peltier element, and the second Peltier element is connected to the controller; the controller is used to energize the second Peltier element, so that the second Peltier element makes the second drive bar deform rapidly through refrigeration and heating, and when the second drive bar deforms rapidly, it drives the first drive bar to move, so that the first lever moves onto the first gear or the second lever moves onto the second gear.

[0010] Preferably, the second drive bar is a shape memory metal bar.

[0011] Furthermore, it further includes an insulating and heat-insulating seat. The first drive bar includes a first upper drive bar and a first lower drive bar. One ends of the first upper drive bar and the first lower drive bar are respectively fixed on both sides of the insulating and heat-insulating seat, and the other ends of the first upper drive bar and the first lower drive bar are respectively fixed on the upper end plate and the lower end plate of the first Peltier element; the first lever is fixed on the first lower drive bar, and the second lever is fixed on the first upper drive bar; the second drive bar includes a second upper drive bar and a second lower drive bar. One ends of the second upper drive bar and the second lower drive bar are respectively fixed at both ends of the insulating and heat-insulating seat, and the other ends of the second upper drive bar and the second lower drive bar are respectively fixed on the upper end plate and the lower end plate of the second Peltier element, and both the second upper drive bar and the second lower drive bar are sleeved on the second fixed pulleys.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] The driving device for drug sustained-release infusion provided by the present invention can achieve sustained-release infusion without a precision micro-motor, has a low cost, does not require a motor, can adjust the infusion speed as needed, and can also switch the injected drug according to requirements. Description of the Drawings

[0014] Figure 1 It is a schematic structural diagram of a driving device for drug sustained - release infusion;

[0015] Figure 2 It is an assembly schematic diagram of a first driving bar, a second driving bar, a first fixed pulley, a second fixed pulley, a first Peltier element and a second Peltier element;

[0016] Figure 3 It is a schematic diagram of a driving device for drug sustained - release infusion installed on an infusion device;

[0017] Figure 4 It is a schematic structural diagram of a first Peltier element. Specific embodiments

[0018] The present invention will be further described below in conjunction with the accompanying drawings.

[0019] Embodiment 1

[0020] As Figures 1 to 3 shown, a driving device for drug sustained - release infusion includes a first lead screw 22, a first gear 21, a first fixed pulley 34, a first lever 36, a first Peltier element 33 and an insulating and heat - insulating seat 35.

[0021] The first lead screw 22 is movably installed on the infusion device 1, and one end of the first lead screw 22 is connected to the first piston 23; the structure of the first gear 21 is similar to that of a ratchet wheel. The first gear 21 is rotatably installed on the infusion device 1. A first spiral groove is provided at the center of the first gear 21. The first lead screw 22 is installed in the first spiral groove. When the first gear 21 rotates, it pushes the first lead screw 22 to move axially through the first spiral groove. The first piston 23 is movably inserted into the first syringe 11 of the infusion device 1. The first Peltier element 33 is fixed on the infusion device 1 and is located below the first gear 21. Four first fixed pulleys 34 are symmetrically provided. Among them, two first fixed pulleys 34 are located on both sides of the first gear 21, and the other two first fixed pulleys 34 are located on both sides of the first Peltier element 33. The first fixed pulleys 34 are rotatably installed on the infusion device 1.

[0022] The first driving bar is a shape memory alloy bar, including a first upper driving bar 32 and a first lower driving bar 31. One end of the first upper driving bar 32 and the first lower driving bar 31 are respectively fixed on both sides of the insulating and heat-insulating seat 35. The other ends of the first upper driving bar 32 and the first lower driving bar 31 are respectively fixed on the upper end plate and the lower end plate of the first Peltier element 33. The first lever 36 is fixed on the first lower driving bar 31. The first upper driving bar 32 and the first lower driving bar 31 form a rectangle, and the splitter plate is located on both sides of the first gear 21. The first upper driving bar 32 and the first lower driving bar 31 are also sleeved on the first fixed pulley 34. The insulating and heat-insulating seat 35 is made of materials such as PP, PVC, XLPE, etc. through processes such as injection molding, ultrasonic welding, and adhesive bonding to achieve fixed connection with the first upper driving bar 32 and the first lower driving bar 31.

[0023] The controller is fixed on the infusion device 1. The controller is connected to the first Peltier element 33 and is used to energize the first Peltier element 33 to make the first Peltier element 33 heat and cool. The first Peltier element 33 causes the first driving bar to contract. The first driving bar pushes the first gear 21 to rotate through the first lever 36, and the first gear 21 pushes the first lead screw 22 and the first piston 23 to move axially.

[0024] The first Peltier element 33 includes semiconductor chips made of N-type and P-type bismuth telluride materials. At the joints of different conductors, heat absorption and heat release effects will respectively occur with the change of the current direction. These chips are connected in series through electrical connections, but are arranged in a parallel thermodynamic arrangement to achieve the best heat transfer performance of high temperature and low temperature in the first Peltier element 33. As Figure 4 shown, the first Peltier element 33 includes an upper end plate 331, a lower end plate 332, an upper copper current-carrying sheet 333, a lower copper current-carrying sheet 334, an N-type semiconductor 335, and a P-type semiconductor 336. Among them, both the upper end plate 331 and the lower end plate 332 are electrically insulating ceramic plates. The upper copper current-carrying sheet 333 is fixed on the upper end plate 331, and the lower copper current-carrying sheet 334 is fixed on the lower end plate 332. One end of the N-type semiconductor 335 is respectively connected to one end of the lower copper current-carrying sheet 334, and the other end is connected to one end of the upper copper current-carrying sheet 333. The other end of the upper copper current-carrying sheet 333 is connected to one end of the P-type semiconductor 336, and the other end of the P-type semiconductor 336 is connected to the lower copper current-carrying sheet 334. The upper copper current-carrying sheet 333, the lower copper current-carrying sheet 334, the N-type semiconductor 335, and the P-type semiconductor 336 are arranged in an array to form a Peltier element. When the upper end plate 331 heats up, the lower end plate 332 cools down, and when the upper end plate 331 cools down, the lower end plate 332 heats up.

[0025] The first drive bar made of shape memory metal returns to its high-temperature shape when heated and can return to its low-temperature shape when cooled. Compared with the traditional use of the thermal expansion and contraction of metal, it can deform faster. The first drive bar is decomposed into a first upper drive bar 32 and a first lower drive bar 31 through the insulating and heat-insulating seat 35, so that they can deform independently and do not interfere with each other.

[0026] The Peltier element effect is that when an electric current passes through a circuit composed of two different conductors, there is a cooling effect at one node and the temperature rises at the other node, and this effect is reversible. By changing the direction of the electric current, the heating and cooling effects at the node can be reversed. The function of being able to heat and cool simultaneously is used to heat and cool the shape memory metal. The shape memory metal selected is a two-way shape memory metal, which returns to its high-temperature shape when heated and can return to its low-temperature shape when cooled. Heating and cooling simultaneously realize the reciprocating movement of the first lever 36. The first lever 36 pushes the first gear 21 to rotate, and then the first lead screw 22 is pushed by the first gear 21 to drive the first piston 23 to output the liquid medicine. One end of the first Peltier element 33 heats and the other end cools. When the electric current is reversed, the heating and cooling surfaces are flipped. One end of the shape memory metal strip can quickly stretch and one end of the metal strip can quickly contract, achieving the purpose of the quick movement of the lever.

[0027] The controller supplies positive electricity to the first Peltier element 33. The upper end plate heats and the lower end plate cools. The first upper drive bar 32 is heated and the first lower drive bar 31 is cooled. The first upper drive bar 32, the first lower drive bar 31 and the first lever 36 move away from the first gear 21, so as to move to one side of the teeth of the first gear 21. Then the controller supplies reverse electricity to the first Peltier element. The upper end plate cools and the lower end plate heats. The first upper drive bar 32 is cooled and the first lower drive bar 31 is heated. The first upper drive bar 32, the first lower drive bar 31 and the first lever 36 move towards the first gear 21 and push the first gear 21 to rotate through the teeth of the first gear 21, and the first gear 21 pushes the first lead screw 22 to extend.

[0028] When all the liquid medicine in the infusion device 1 is used up, the first piston 23 and the first lead screw 22 can be manually reset.

[0029] The infusion speed can be adjusted by adjusting the current of the first Peltier element 33 to adjust the cooling and heating speeds. The cooling and heating speeds will affect the deformation speed of the first drive bar made of shape memory metal, thereby realizing the adjustment of the moving speed of the first lever 36 and finally realizing the adjustment of the infusion speed.

[0030] This embodiment realizes slow-release infusion without using a precision drive motor, with low cost, small size and the ability to adjust the infusion speed.

[0031] Embodiment Two

[0032] On the basis of the above-mentioned first embodiment, for double-drug infusion, it further includes a second lead screw 42, a second gear 41, a second lever 55, a second fixed pulley 54, a second driving strip, and a second Peltier element 53. The second lead screw 42 is movably installed on the infusion device 1. The second lead screw 42 is located on one side of the first lead screw 22 and is connected to the second piston 43. The structure of the second gear 41 is similar to that of a ratchet. The second gear 41 is rotatably installed on the infusion device 1. The second gear 41 is located on one side of the first gear 21 and is arranged staggeredly with the first gear 21. A second spiral groove is provided at the center of the second gear 41, and the second lead screw 42 is installed in the second spiral groove. The second driving strip includes a second upper driving strip 52 and a second lower driving strip 51. One ends of the second upper driving strip 52 and the second lower driving strip 51 are respectively fixed at both ends of the insulating and heat-insulating seat 35, and the other ends of the second upper driving strip 52 and the second lower driving strip 51 are respectively fixed on the upper end plate and the lower end plate of the second Peltier element 53.

[0033] The second lever 55 is fixed on the first driving strip and is located on one side of the second gear 41. A plurality of second fixed pulleys 54 are provided and are located between the first gear 21 and the second gear 41. The first fixed pulley 34 is arranged horizontally, and the second fixed pulley 54 is arranged vertically. The second driving strip is a shape memory alloy strip. The second driving strip includes a second upper driving strip 52 and a second lower driving strip 51. One ends of the second upper driving strip 52 and the second lower driving strip 51 are respectively fixed at both ends of the insulating and heat-insulating seat 35, and the other ends of the second upper driving strip 52 and the second lower driving strip 51 are respectively fixed on the upper end plate and the lower end plate of the second Peltier element 53. The second upper driving strip 52 and the second lower driving strip 51 form a rectangle and are located between the first gear 21 and the second gear 41. The second upper driving strip 52 and the second lower driving strip 51 are also sleeved on the second fixed pulley 54.

[0034] In the initial state, the first lever 36 is not in contact with the first gear 21, and the second lever 55 is not in contact with the second gear 41. When it is necessary to infuse the drug with the first syringe 11, the controller supplies positive electricity to the second Peltier element 53. The upper end plate generates heat, and the lower end plate cools. The second upper driving strip 52 is heated, and the second lower driving strip 51 is cooled. The second upper driving strip 52 and the second lower driving strip 51 move towards the first gear 21. The first upper driving strip 32, the first lower driving strip 31, and the first lever 36 move to the position of the first gear 21. Then the controller supplies electricity to the first Peltier element 33 to infuse the drug with the first syringe 11.

[0035] When the second syringe 12 needs to infuse the liquid medicine, the controller reversely powers on the second Peltier element 53, the upper end plate is cooled, the lower end plate is heated, the second upper driving bar 52 is cooled, the second lower driving bar 51 is heated, the second upper driving bar 52 and the second lower driving bar 51 move towards the second gear 41, the second upper driving bar 52, the second lower driving bar 51 and the second lever 55 move to the position of the second gear 41, and then the controller powers on the first Peltier element 33 to infuse the liquid medicine with the second syringe 12, realizing the infusion of double medicines.

[0036] Compared with the traditional driving mode, the present invention realizes the injection of double liquid medicines by using the Peltier element and the shape memory alloy without using a driving motor, and can adjust the injection speed, and has a smaller volume and a lower price under the condition of complete functions.

[0037] The technical principle of the present invention has been described above in conjunction with specific embodiments. These descriptions are only for explaining the principle of the present invention and cannot be construed as limiting the protection scope of the present invention in any way. Based on the explanations herein, those skilled in the art can readily conceive of other specific embodiments of the present invention without creative efforts, and these embodiments will fall within the protection scope of the claims of the present invention.

Claims

1. A driving device for drug sustained-release infusion, characterized in that, Comprising: A first lead screw (22), the first lead screw (22) is movably installed on the infusion device (1) and is connected to a first piston (23); A first gear (21), the first gear (21) is rotatably installed on the infusion device (1), a first spiral groove is provided at the center of the first gear (21), and the first lead screw (22) is installed in the first spiral groove; A plurality of first fixed pulleys (34), the first fixed pulleys (34) are installed on the infusion device (1) and are located on both sides of the first gear (21); A first drive bar, the first drive bar is a metal bar, and the first drive bar is sleeved on the first fixed pulley (34); A first shift lever (36), the first shift lever (36) is fixed on the first drive bar and is located on one side of the first gear (21); A first Peltier element (33), the first Peltier element (33) is fixed on the infusion device (1) and is located below the first gear (21), and both ends of the first drive bar are respectively fixed on the upper end plate and the lower end plate of the first Peltier element (33); And A controller, the controller is connected to the first Peltier element (33), and is used to make the first Peltier element (33) quickly deform the first drive bar through refrigeration and heating, and push the first gear (21) to rotate through the first shift lever (36), and the first gear (21) pushes the first lead screw (22) and the first piston (23) to move axially; Wherein, the first Peltier element (33) includes semiconductor chips made of N-type and P-type bismuth telluride materials. When the upper end plate (331) is heated, the lower end plate (332) is cooled, and when the upper end plate (331) is cooled, the lower end plate (332) is heated.

2. The driving device for drug sustained-release infusion according to claim 1, characterized in that, The first drive bar is a shape memory metal bar.

3. The driving device for drug sustained-release infusion according to claim 2, characterized in that, Further comprising an insulating and heat-insulating seat (35), the first drive bar includes a first upper drive bar (32) and a first lower drive bar (31), one ends of the first upper drive bar (32) and the first lower drive bar (31) are respectively fixed on both sides of the insulating and heat-insulating seat (35), the other ends of the first upper drive bar (32) and the first lower drive bar (31) are respectively fixed on the upper end plate and the lower end plate of the first Peltier element (33), and the first shift lever (36) is fixed on the first lower drive bar (31); Both the first upper drive bar (32) and the first lower drive bar (31) are sleeved on the first fixed pulley (34).

4. The driving device for drug sustained-release infusion according to claim 1, characterized in that, Further comprising: A second lead screw (42), the second lead screw (42) is movably installed on the infusion device (1) and is connected to a second piston (43); A second gear (41), the second gear (41) is rotatably installed on the infusion device (1), the second gear (41) is located on one side of the first gear (21) and is arranged staggeredly with the first gear (21), a second spiral groove is provided at the center of the second gear (41), and the second lead screw (42) is installed in the second spiral groove; A second lever (55), the second lever (55) is fixed on the first drive bar and is located on one side of the second gear (41); A second fixed pulley (54), there are several of the second fixed pulleys (54), which are installed on the infuser (1) and are located between the first gear (21) and the second gear (41); A second drive bar, the second drive bar is a metal bar, the second drive bar is sleeved on the second fixed pulley (54) and is fixedly connected to the first drive bar; and A second Peltier element (53), the second Peltier element (53) is fixed on the infuser (1), the second Peltier element (53) is perpendicular to the first Peltier element (33), and both ends of the second drive bar are respectively fixed on the upper end plate and the lower end plate of the second Peltier element (53), and the second Peltier element (53) is connected to the controller; The controller is used to energize the second Peltier element (53), so that the second Peltier element (53) makes the second drive bar deform rapidly through refrigeration and heating. When the second drive bar deforms rapidly, it drives the first drive bar to move, so that the first lever (36) moves onto the first gear (21) or the second lever (55) moves onto the second gear (41).

5. The driving device for drug sustained-release infusion according to claim 4, characterized in that, The second drive bar is a shape memory metal bar.

6. The driving device for drug sustained-release infusion according to claim 5, characterized in that, It further includes an insulating and heat-insulating seat (35). The first drive bar includes a first upper drive bar (32) and a first lower drive bar (31). One ends of the first upper drive bar (32) and the first lower drive bar (31) are respectively fixed on both sides of the insulating and heat-insulating seat (35), and the other ends of the first upper drive bar (32) and the first lower drive bar (31) are respectively fixed on the upper end plate and the lower end plate of the first Peltier element (33); the first lever (36) is fixed on the first lower drive bar (31), and the second lever (55) is fixed on the first upper drive bar (32); The second drive bar includes a second upper drive bar (52) and a second lower drive bar (51). One ends of the second upper drive bar (52) and the second lower drive bar (51) are respectively fixed at both ends of the insulating and heat-insulating seat (35), and the other ends of the second upper drive bar (52) and the second lower drive bar (51) are respectively fixed on the upper end plate and the lower end plate of the second Peltier element (53), and both the second upper drive bar (52) and the second lower drive bar (51) are sleeved on the second fixed pulley (54).

Citation Information

Patent Citations

  • Driving device for drug sustained-release infusion

    CN217566996U