Reagent filling device and sample analyzer having the same
By optimizing the reagent filling device structure of the sample analyzer, using a combined design of horizontal rotation assembly, vertical lift assembly and cantilever assembly, the contradiction between the reagent filling device in motion independence and space occupation is solved, and miniaturized and efficient reagent filling is achieved.
Patent Information
- Application Number
- CN202011642583.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-12-31
- Publication Date
- 2025-08-05
- Estimated Expiration
- 2040-12-31
AI Technical Summary
The reagent filling device of the existing sample analyzer is difficult to take into account both the independence of movement and the occupation of space, resulting in large size, large area and low working efficiency.
The combined design of horizontal rotation assembly, vertical lift assembly and cantilever assembly is adopted. The cantilever assembly is dislocated in height and length and short arms. The rotation center is located in the reagent disk. The multiple arm components act independently of each other in the horizontal and vertical directions, reducing the rotation angle and space occupied.
It effectively reduces the space occupied by the reagent filling device, improves working efficiency, reduces the requirements for motor motion load, and ensures the reliability and efficiency of reagent filling.
Smart Images

Figure CN114689897B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to a sample analyzer device, and in particular to a reagent filling device and a sample analyzer having the same. Background Art
[0002] Taking the fully automatic biochemical analyzer as an example, a fully automatic biochemical analyzer is an instrument that measures specific chemical components in body fluids based on the principle of photoelectric colorimetry. It mainly includes a reagent storage system, a sample loading system, a reaction system, an optical system, and a fluid control system. Among them, the reagent filling device in the sample loading system is an indispensable component, responsible for drawing reagents from the reagent storage system and adding them to the cuvette in the reaction system. In high-speed fully automatic biochemical analyzers, the cuvettes in the reaction system are generally arranged in an inner and outer double circle, so two sets of reagent filling devices are required, corresponding to the inner and outer cuvettes respectively, to achieve independent filling of reagents in the inner and outer circles. How to rationally design two sets of reagent filling devices to improve the instrument's operating efficiency while reducing the space occupied by components has always been a technical bottleneck facing high-speed fully automatic biochemical analyzers.
[0003] The prior art provides three types of reagent filling devices, and their limitations are as follows:
[0004] 1. A reagent filling device that performs circular and up-and-down motions, with two arm assemblies located on the same side. The two arm assemblies can only move simultaneously, filling reagents in the same direction and at the same angle, and cannot move independently of each other, resulting in low work efficiency.
[0005] 2. A reagent filling device that performs circular and vertical motion. The rotation center of its horizontal circular motion can only be on its main structural body. To allow the two arm assemblies to move independently without interfering with each other, the two arm assemblies must be arranged in opposite directions. However, this opposite arrangement occupies a large planar area of the instrument, resulting in a large footprint for the entire device. In addition, due to the opposite arrangement, the arm assembly rotates by an angle greater than 180 degrees during movement, and its horizontal motion trajectory is long. This places greater demands on the driving motion load within the limited sample loading cycle of a high-speed fully automatic biochemical analyzer.
[0006] 3. The prior art also provides a reagent dispensing device capable of three-dimensional movement in the X, Y, and Z directions. This device can dispense samples and reagents from any location within a rectangular area. However, it is bulky, occupying a significant area of the instrument's floor plan, which is inconvenient for overall layout. Furthermore, its complex structure makes software control prone to errors, resulting in high costs and limited widespread application. Summary of the Invention
[0007] The main purpose of the present invention is to provide a reagent filling device and a sample analyzer having the same, so as to solve the problem in the prior art that the reagent filling device of the sample analyzer cannot balance the independent movement and space occupation.
[0008] In order to achieve the above-mentioned purpose, according to one aspect of the present invention, a reagent filling device is provided, comprising a base, a horizontal rotation assembly, a vertical lifting assembly and a cantilever assembly, wherein the horizontal rotation assembly is connected to the base; the vertical lifting assembly is connected to the horizontal rotation assembly, and the vertical lifting assembly can move in the vertical direction relative to the base; the cantilever assembly is connected to the vertical lifting assembly, and the vertical lifting assembly can drive the cantilever assembly to move in the vertical direction, and the cantilever assembly is rotatably arranged relative to the vertical lifting assembly; there are multiple cantilever assemblies, and the multiple cantilever assemblies are staggered in the vertical direction, and the multiple cantilever assemblies are located on the same side, the cantilever assembly includes a cantilever body, the length of the cantilever body of at least one of the multiple cantilever assemblies is greater than the length of the cantilever bodies of the remaining cantilever assemblies, and the cantilever assembly is used to add the reagent in the reagent disk into the reaction cup in the reaction disk.
[0009] Furthermore, there are multiple horizontal rotation assemblies and multiple vertical lifting assemblies, and the multiple horizontal rotation assemblies are arranged in a one-to-one correspondence with the multiple vertical lifting assemblies. Each cantilever assembly is correspondingly provided with a horizontal rotation assembly and a vertical lifting assembly.
[0010] Furthermore, the projection of the rotation center of the cantilever assembly on the horizontal plane is located within the reagent disk.
[0011] Furthermore, the vertical lifting assembly includes a lifting body, a first transmission part, a second transmission part, a transmission member and a transmission shaft, wherein the first transmission part is arranged at the first end of the lifting body, and the first transmission part is connected to the horizontal rotation assembly; the second transmission part is arranged at the second end of the lifting body, and the cantilever assembly is connected to the second transmission part; the first end of the transmission member is connected to the first transmission part, and the second end of the transmission member is connected to the second transmission part, and the horizontal rotation assembly transmits power to the second transmission part through the first transmission part and the transmission member to drive the cantilever assembly to rotate; the second transmission part is connected to the transmission shaft, and the cantilever assembly is connected to the other end of the transmission shaft, and the axis of the transmission shaft is the rotation center of the cantilever assembly.
[0012] Furthermore, the transmission shaft includes: a first transmission shaft and a second transmission shaft, and the length of the first transmission shaft is greater than the length of the second transmission shaft.
[0013] Furthermore, the transmission member is a transmission belt; or, the transmission member is a rack or a chain.
[0014] Furthermore, the horizontal rotation assembly includes a first driving part and a ball spline shaft, wherein the first driving part is connected to the base; the ball spline shaft is connected to the first driving part, and the first transmission part is sleeved on the outer peripheral side of the ball spline shaft. The first driving part is used to drive the ball spline shaft to rotate, so that the ball spline shaft drives the first transmission part to rotate.
[0015] Furthermore, the vertical lifting assembly includes a second driving part, a ball screw and a screw nut, wherein the second driving part is connected to the base; the ball screw is connected to the second driving part; the screw nut is sleeved on the outer peripheral side of the ball screw and connected to the lifting body, and the second driving part can drive the lifting body to drive the cantilever assembly to move in the vertical direction.
[0016] Furthermore, the lifting body is provided with an assembly hole for installing the lead screw nut, and the assembly hole is located between the first transmission part and the second transmission part.
[0017] Furthermore, the first transmission part includes a first sleeve, which is sleeved on the ball spline shaft, the first sleeve is connected to the lifting body, and the transmission part is connected to the first sleeve; when the second driving part drives the lifting body to move in the vertical direction, the lifting body drives the first sleeve to move in the vertical direction relative to the ball spline shaft, and when the first driving part drives the ball spline shaft to rotate, the ball spline shaft drives the first sleeve to rotate horizontally relative to the lifting body, so as to drive the cantilever assembly to rotate through the transmission part.
[0018] Furthermore, a second sleeve is fixedly provided on the outer circumference of the first sleeve, the first sleeve is connected to the lifting body through the second sleeve, one end of the second sleeve is connected to the transmission member, and the first sleeve and the second sleeve are rotatably provided relative to the lifting body.
[0019] Furthermore, meshing teeth that cooperate with the transmission member are provided on the outer circumferential surface of the second sleeve.
[0020] Furthermore, the second transmission part includes a transmission plate, which is movably connected to the lifting body and connected to the transmission shaft. The outer peripheral surface of the transmission plate is provided with meshing teeth for cooperating with the transmission member, and the transmission plate can drive the transmission shaft to rotate.
[0021] Furthermore, the first end of the cantilever body is connected to the transmission shaft, and the cantilever assembly also includes an anti-collision mechanism and a reagent needle, wherein the anti-collision mechanism is connected to the second end of the cantilever body; and the reagent needle is connected to the anti-collision mechanism.
[0022] Furthermore, the reagent tray has multiple circles of reagent bottles along its radial direction, and the reaction tray has multiple circles of reaction cups along its radial direction. The cantilever assembly is used to add reagents in the reagent bottles of each layer into the reaction cups in the reaction tray.
[0023] Further, the multi-loop reagent bottles include at least two loops of reagent bottles. The two loops of reagent bottles include an inner-loop reagent bottle and an outer-loop reagent bottle. The multi-loop reaction cups include at least two loops of reaction cups. The two loops of reaction cups include an inner-loop reaction cup and an outer-loop reaction cup. The cantilever assembly includes a first cantilever assembly and a second cantilever assembly. The length of the cantilever body of the first cantilever assembly is greater than that of the second cantilever assembly. The first cantilever assembly is used to add the reagent in the inner-loop reagent bottle to at least one of the inner-loop reaction cup and the outer-loop reaction cup. The second cantilever assembly is used to add the reagent in the outer-loop reagent bottle to at least one of the inner-loop reaction cup and the outer-loop reaction cup; or the first cantilever assembly is used to add the reagent in the outer-loop reagent bottle to at least one of the inner-loop reaction cup and the outer-loop reaction cup, and the second cantilever assembly is used to add the reagent in the inner-loop reagent bottle to at least one of the inner-loop reaction cup and the outer-loop reaction cup. Further, the rotation angle a of the first cantilever assembly satisfies: 0 < a ≤ 120°, and / or the rotation angle b of the second cantilever assembly satisfies: 0 < b ≤ 90°.
[0024] Further, the vertical lifting assembly further includes a support bushing for supporting the first cantilever assembly.
[0025] According to another aspect of the present invention, there is provided a sample analyzer, including a reagent filling device, and the reagent filling device is the above-mentioned reagent filling device.
[0026] Further, the sample analyzer includes a plurality of reagent trays and reagent filling devices provided corresponding to the plurality of reagent trays one by one.
[0027] Applying the technical solution of the present invention, by optimizing the structure of the reagent filling device of the sample analyzer, the reagent filling device has a horizontal rotation assembly, a vertical lifting assembly and a cantilever assembly. The cantilever assemblies are concentrated together, greatly reducing the occupied space. The cantilever assemblies are arranged with different heights and long and short arms. In this way, the actions of the multiple arm assemblies are independent of each other in the horizontal and vertical directions, and can all suck reagents from the inner and outer circles of the reagent tray without interfering with each other, improving the working efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0028] The accompanying drawings forming a part of this application are used to provide a further understanding of the present invention. The schematic embodiments and descriptions thereof of the present invention are used to explain the present invention and do not constitute an improper limitation to the present invention. In the drawings:
[0029] Figure 1 Shows a layout schematic diagram of a reagent filling device, a reagent tray and a reaction tray according to an optional embodiment of the present invention;
[0030] Figure 2 Shows Figure 1 the structural schematic diagram of the reagent filling device in
[0031] Figure 3 Shown Figure 2 A schematic cross-sectional view of the reagent filling device from another perspective;
[0032] Figure 4 Shown Figure 3 Schematic diagram of the enlarged structure at A in FIG;
[0033] Figure 5 Shown Figure 3 A schematic structural diagram of the cantilever assembly of the reagent filling device;
[0034] Figure 6 Shown Figure 4 A schematic diagram of the assembly structure of the lifting body, the first transmission part and the second transmission part of the vertical lifting assembly;
[0035] Figure 7 Shown Figure 3 A schematic structural diagram of the first cantilever assembly of the reagent filling device;
[0036] Figure 8 Shown Figure 3 Another structural diagram of the cantilever assembly of the reagent filling device
[0037] Figure 9 Shown Figure 4 Another structural diagram of the vertical lifting assembly of the lifting body and the first transmission part and the second transmission part
[0038] Figure 10 Shown Figure 3 Schematic diagram of the structure of the second cantilever assembly of the reagent filling device in the figure, wherein the above figure includes the following figure numbers:
[0039] 1. Reagent tray; 2. Reaction tray; 3. Reagent filling device; 1022. Coupling; 1023. Support bearing; 402. Wire holder fixing plate; 10. Base; 20. Horizontal rotation assembly; 30. Vertical lifting assembly; 40. Cantilever assembly; 100. Reaction cup; 31. Lifting body; 32. First transmission unit; 33. Second transmission unit; 34. Transmission belt; 35. Transmission shaft; 351. First transmission shaft; 352. Second transmission shaft. 211. First drive unit; 212. Ball spline shaft; 36. Second drive unit; 37. Ball screw; 38. Screw nut; 39. Assembly hole; 321. First sleeve; 322. Second sleeve; 3221. Bearing; 3222. Key; 331. Transmission plate; 41. Cantilever body; 42. Anti-collision mechanism; 43. Reagent needle; 200. Reagent bottle; 44. First cantilever assembly; 45. Second cantilever assembly; 47. Support sleeve. DETAILED DESCRIPTION
[0040] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.
[0041] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components and / or combinations thereof.
[0042] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that the terms used in this way are interchangeable where appropriate, so that the embodiments of the present application described herein can, for example, be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.
[0043] Now, exemplary embodiments according to the present application will be described in more detail with reference to the accompanying drawings. However, these exemplary embodiments can be implemented in a variety of different forms and should not be interpreted as being limited to the embodiments described herein. It should be understood that these embodiments are provided to make the disclosure of this application thorough and complete, and to fully convey the concepts of these exemplary embodiments to those of ordinary skill in the art. In the accompanying drawings, for the sake of clarity, the thickness of layers and regions may be exaggerated, and the same reference numerals are used to represent the same devices, and thus their descriptions will be omitted.
[0044] In order to solve the problem of a large occupied area of a reagent filling device of a sample analyzer in the prior art, the present invention provides a reagent filling device and a sample analyzer, wherein the sample analyzer includes a reagent filling device 3 .
[0045] Furthermore, the sample analyzer includes a plurality of reagent discs 1 and a reagent filling device 3 provided in one-to-one correspondence with the plurality of reagent discs 1 .
[0046] Specifically, if Figures 1 to 5As shown, the reagent filling device 3 in the present application includes a base 10, a horizontal rotation component 20, a vertical lifting component 30 and a cantilever component 40. Wherein, the horizontal rotation component 20 is connected to the base 10, and the vertical lifting component 30 is connected to the horizontal rotation component 20, and is also connected to the base 10, and the vertical lifting component 30 can move in the vertical direction relative to the base 10. The cantilever component 40 is connected to the vertical lifting component 30, and the vertical lifting component 30 can drive the cantilever component 40 to move in the vertical direction. Moreover, the cantilever component 40 is rotatably arranged relative to the vertical lifting component 30, and the projection of the rotation center of the cantilever component 40 on the horizontal plane is located in the reagent disk 1, and the cantilever component 40 is used to add the reagent in the reagent disk 1 into the reaction cup 100 in the reaction disk 2.
[0047] By optimizing the structure of the reagent filling device of the sample analyzer, the reagent filling device includes a horizontal rotation component 20, a vertical lifting component 30 and a cantilever component 40, wherein the cantilever component 40 is connected to the vertical lifting component 30 and the horizontal rotation component 20, and the cantilever component 40 can rotate relative to the vertical lifting component 30, and the projection of the rotation center of the cantilever component 40 on the horizontal plane is located within the reagent disk 1. In this way, on the one hand, in the process of the cantilever component 40 adding the reagent from the reagent disk 1 into the reaction cup 100 in the reaction disk 2, the cantilever component 40 only needs to rotate a small angle to achieve the addition of the reagent, which greatly reduces the rotation angle of the cantilever component 40; on the other hand, it is also beneficial to reduce the arm length of the cantilever component 40, thereby facilitating the compact design of the reagent filling device, ensuring that the overall volume of the reagent filling device is small, and further ensuring that the reagent filling device does not occupy a large installation space; in addition, since the rotation angle of the cantilever component 40 is small, it is beneficial to reduce the requirements for the motor motion load within the limited sample addition cycle of the sample analyzer.
[0048] It should be noted that in the present application, the cantilever assemblies are concentrated together, which greatly reduces the installation space. The cantilever assemblies are staggered in height and designed with long and short arms, so that the multiple arm assemblies move independently in the horizontal and vertical directions, and can all reach the inner and outer circles of the reagent disk to absorb reagents without interfering with each other, thereby improving work efficiency. Moreover, the rotation center is located on the outside, so that the addition of reagents can be achieved by rotating a smaller angle, which greatly reduces the rotation angle of the cantilever assembly and reduces the occupied space.
[0049] It should be noted that, in the present application, the reagents in the reagent disk 1 may be samples, cleaning fluids, and the like.
[0050] like Figure 5 、 Figure 6 、 Figure 8 and Figure 9As shown, the vertical lift assembly 30 includes a lift body 31, a first transmission unit 32, a second transmission unit 33, and a transmission member. The first transmission unit 32 is disposed at the first end of the lift body 31 and is connected to the horizontal rotation assembly 20. The second transmission unit 33 is disposed at the second end of the lift body 31, and the cantilever assembly 40 is connected to the second transmission unit 33. The first end of the transmission member is connected to the first transmission unit 32, and the second end of the transmission member is connected to the second transmission unit 33. The horizontal rotation assembly 20 transmits power to the second transmission unit 33 through the first transmission unit 32 and the transmission member, thereby driving the cantilever assembly 40 to rotate.
[0051] like Figure 6 As shown, the transmission member is a transmission belt 34 .
[0052] Optionally, in an embodiment of the present application not shown in the figures, the transmission member is a rack or a chain.
[0053] like Figure 5 、 Figure 6 、 Figure 8 and Figure 9 As shown, the vertical lifting assembly 30 includes a transmission shaft 35, the second transmission portion 33 is connected to the transmission shaft 35, and the cantilever assembly 40 is connected to the transmission shaft 35. The axis of the transmission shaft 35 is the rotation center of the cantilever assembly 40. In this way, the vertical projection of the rotation center of the cantilever assembly 40 is ensured to be located within the reagent disk 1, thereby facilitating a reduction in the rotation angle of the cantilever assembly 40.
[0054] To ensure that the cantilever assembly 40 can absorb the reagent in the reagent disk 1, as shown in FIG. Figures 3 to 5 As shown, the vertical lifting assembly 30 includes a second drive unit 36, a ball screw 37, and a screw nut 38. The second drive unit 36 is connected to the base 10; the ball screw 37 is connected to the second drive unit 36; the screw nut 38 is sleeved on the outer circumference of the ball screw 37 and connected to the lifting body 31. The second drive unit 36 can drive the lifting body 31 to drive the cantilever assembly 40 to move in the vertical direction. In this way, the second drive unit 36 drives the ball screw 37 to rotate, thereby driving the screw nut 38 to move axially along the ball screw 37. While converting the rotational motion into vertical motion, it can also ensure the smooth movement of the cantilever assembly 40, thereby ensuring that the cantilever assembly 40 can move downward to approach the reagent in the reagent tray 1 and absorb the reagent.
[0055] like Figure 3 As shown, the ball screw 37 is mounted on the support frame of the base 10 through upper and lower support bearings 1023 and is connected to the second driving part 36 through a coupling 1022 .
[0056] Optionally, the vertical lifting assembly 30 is not limited to the transmission method of the ball screw 37 and the screw nut 38, and may also include a trapezoidal screw, a synchronous belt or a chain.
[0057] like Figure 6 、 Figure 9 As shown, the lifting body 31 is provided with an assembly hole 39 for mounting the lead screw nut 38. The assembly hole 39 is located between the first transmission portion 32 and the second transmission portion 33. Thus, the provision of the assembly hole 39 ensures the reliable installation of the lifting body 31, thereby ensuring the reliable installation of the cantilever assembly 40 connected to the lifting body 31.
[0058] like Figures 3 to 5 、 Figure 8 As shown, the horizontal rotation assembly 20 includes a first drive unit 211 and a ball spline shaft 212. The first drive unit 211 is connected to the base 10; the ball spline shaft 212 is connected to the first drive unit 211. The first transmission unit 32 is sleeved around the outer circumference of the ball spline shaft 212. The first drive unit 211 is used to drive the ball spline shaft 212 to rotate, which in turn drives the first transmission unit 32 to rotate. This ensures smooth transmission of the horizontal rotation assembly 20, thereby ensuring smooth rotation of the first transmission unit 32.
[0059] like Figure 3 and Figure 4 As shown, the first transmission part 32 includes a first sleeve 321, which is sleeved on the ball spline shaft 212, the first sleeve 321 is connected to the lifting body 31, the transmission part is connected to the first sleeve 321, and the first sleeve 321 is rotatably arranged relative to the lifting body 31, the outer surface of the ball spline shaft 212 is provided with a groove, and balls are provided between the inner surface of the first sleeve 321 and the ball spline shaft 212, and some of the balls are located in the groove; when the second driving part 36 drives the lifting body 31 to move in the vertical direction, the lifting body 31 drives the first sleeve 321 to move in the vertical direction relative to the ball spline shaft 212, and when the first driving part 211 drives the ball spline shaft 212 to rotate, the ball spline shaft 212 drives the first sleeve 321 to rotate horizontally relative to the lifting body 31 through the balls, so as to drive the cantilever assembly 40 to rotate through the transmission part. In this way, it is ensured that the cantilever assembly 40 can move in the vertical direction and rotate in the horizontal direction, which is beneficial to improving the efficiency of the reagent filling device in filling reagents.
[0060] like Figure 3 As shown, the ball spline shaft 212 is mounted on the support frame of the base 10 through upper and lower support bearings 1023 and is connected to the first driving part 211 through a coupling 1022 .
[0061] like Figure 4As shown, a second sleeve 322 is fixedly mounted on the outer circumference of the first sleeve 321. The first sleeve 321 is connected to the lifting body 31 via the second sleeve 322. One end of the second sleeve 322 is connected to a transmission member. The second sleeve 322 is connected to the lifting body 31 via a bearing 3221. The first sleeve 321 and the second sleeve 322 are connected via a key 3222. The first sleeve 321 and the second sleeve 322 are rotatably mounted relative to the lifting body 31 via the bearing 3221. This ensures smooth rotation of the first sleeve 321 and the second sleeve 322.
[0062] Optionally, meshing teeth that mate with the transmission member are provided on the outer circumference of the second sleeve 322. This allows a pulley drive between the second sleeve 322 and the transmission member, ensuring smooth transmission between the second sleeve 322 and the transmission member. This facilitates a compact design of the reagent filling device while also ensuring smooth transmission between the second sleeve 322 and the transmission member.
[0063] like Figure 6 、 Figure 9 As shown, the second transmission portion 33 includes a transmission disc 331, which is movably connected to the lifting body 31 and connected to the transmission shaft 35. The outer circumference of the transmission disc 331 is provided with meshing teeth for cooperating with the transmission member, and the transmission disc 331 can drive the transmission shaft 35 to rotate. In this way, a pulley drive is used between the transmission disc 331 and the transmission member, ensuring smooth transmission between the transmission disc 331 and the transmission member. This not only facilitates the compact design of the reagent filling device, but also ensures smooth transmission between the transmission disc 331 and the transmission member.
[0064] like Figure 6 、 Figure 9 As shown, the transmission shaft 35 includes a first transmission shaft 351 and a second transmission shaft 352. The length of the first transmission shaft 351 is greater than the length of the second transmission shaft 352, ensuring a sufficient vertical height difference between the multiple cantilever assemblies 40 to avoid interference. Alternatively, the multiple cantilever assemblies 40 are connected to both ends of the transmission shaft 35 to ensure a sufficient vertical height difference to avoid interference.
[0065] like Figure 5 and Figure 7 As shown, the cantilever assembly 40 includes a cantilever body 41, an anti-collision mechanism 42, and a reagent needle 43. The first end of the cantilever body 41 is connected to the second transmission shaft 352; the anti-collision mechanism 42 is connected to the second end of the cantilever body 41; and the reagent needle 43 is connected to the anti-collision mechanism 42. This ensures the stability of the cantilever assembly 40. The anti-collision mechanism 42 prevents the reagent needle 43 from colliding, thereby preventing the cantilever assembly 40 from being damaged by the reagent needle 43 and thus preventing the reagent aspiration operation from being completed.
[0066] like Figure 8and Figure 10 As shown, the cantilever assembly 40 includes a cantilever body 41, an anti-collision mechanism 42, and a reagent needle 43. The first end of the cantilever body 41 is connected to the first transmission shaft 351; the anti-collision mechanism 42 is connected to the second end of the cantilever body 41; and the reagent needle 43 is connected to the anti-collision mechanism 42. This ensures the stability of the cantilever assembly 40. The anti-collision mechanism 42 prevents the reagent needle 43 from colliding, thereby preventing the cantilever assembly 40 from being damaged by the reagent needle 43 and thus preventing the reagent aspiration operation from being completed.
[0067] Optionally, multiple cantilever assemblies 40 are provided, staggered vertically and located on the same side, with each cantilever assembly 40 correspondingly provided with a horizontal rotation assembly 20 and a vertical lifting assembly 30. This ensures that the cantilever assemblies 40 do not interfere with each other during reagent aspiration or addition, thereby ensuring the reliability of reagent addition by the reagent filling device. Furthermore, multiple cantilever assemblies 40 can improve the efficiency of reagent addition by the reagent filling device.
[0068] Optionally, the length of the cantilever body 41 of at least one cantilever assembly 40 among the plurality of cantilever assemblies 40 is greater than the length of the cantilever bodies 41 of the remaining cantilever assemblies 40. In this way, it is ensured that the cantilever assemblies 40 do not interfere with each other during the operation of aspirating or adding reagents.
[0069] Optionally, the reagent tray 1 has multiple circles of reagent bottles 200 along its radial direction, and the reaction tray 2 has multiple circles of reaction cups 100 along its radial direction, and the cantilever assembly 40 is used to add reagents from the reagent bottles 200 in each circle into the reaction cups 100 in the reaction tray 2. This helps improve the reagent filling efficiency of the reagent filling device.
[0070] like Figure 1As shown in the figure, the multi-loop reagent bottle 200 includes at least two loops of reagent bottles. The two loops of reagent bottles include an inner-loop reagent bottle and an outer-loop reagent bottle. The multi-loop reaction cup 100 includes at least two loops of reaction cups. The two loops of reaction cups include an inner-loop reaction cup and an outer-loop reaction cup. The cantilever assembly 40 includes a first cantilever assembly 44 and a second cantilever assembly 45. The first cantilever assembly 44 is connected to one end of the first transmission shaft 351. The axis of the first transmission shaft 351 is the rotation center of the first cantilever assembly 44. There is a second transmission shaft 352. The second cantilever assembly 45 is connected to one end of the second transmission shaft 352. The axis of the second transmission shaft 352 is the rotation center of the second cantilever assembly 40. And the length of the cantilever body 41 of the first cantilever assembly 44 is greater than the length of the cantilever body 41 of the second cantilever assembly 45. And there is a certain height difference between the first cantilever assembly 44 and the second cantilever assembly 45 in the vertical direction. The first cantilever assembly 44 is used to add the reagent in the inner-loop reagent bottle into the inner-loop reaction cup. The second cantilever assembly 45 is used to add the reagent in the outer-loop reagent bottle into the outer-loop reaction cup; or, the first cantilever assembly 44 is used to add the reagent in the inner-loop reagent bottle into the outer-loop reaction cup. The second cantilever assembly 45 is used to add the reagent in the outer-loop reagent bottle into the inner-loop reaction cup. Or, the first cantilever assembly 44 is used to add the reagent in the outer-loop reagent bottle into the inner-loop reaction cup. The second cantilever assembly 45 is used to add the reagent in the inner-loop reagent bottle into the outer-loop reaction cup; or, the first cantilever assembly 44 is used to add the reagent in the outer-loop reagent bottle into the outer-loop reaction cup. The second cantilever assembly 45 is used to add the reagent in the inner-loop reagent bottle into the inner-loop reaction cup. In this way, while ensuring the bearing stability of the reagent tray 1 and the bearing stability of the reaction tray 2, it is beneficial to improve the reagent filling efficiency of the reagent filling device.
[0071] As Figure 9 shown in the figure, the vertical lifting assembly 30 further includes a support bushing 47, which is used to support the first cantilever assembly 44, increase the height difference between the first cantilever assembly 44 and the second cantilever assembly 45, and avoid interference. In the present application, the projection of the rotation center of the cantilever assembly 40 on the horizontal plane is located inside the reagent tray 1 and outside the cantilever assembly. By optimizing the rotation centers of the first cantilever assembly 44 and the second cantilever assembly 45, the rotation angles of the first cantilever assembly 44 and the second cantilever assembly 45 are greatly reduced. As Figure 1 shown in the figure, the rotation angle a of the first cantilever assembly 44 satisfies: 0 < a ≤ 120°, and / or, the rotation angle b of the second cantilever assembly 45 satisfies: 0 < b ≤ 90°. Only a small rotation angle is required to achieve the addition of the reagent, greatly reducing the occupied space.
[0072] It should be noted that in the present application, the sample analyzer can be a chemiluminescence analyzer, a coagulation analyzer, a blood cell analyzer, etc.
[0073] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used herein to describe the spatial positional relationship of a device or feature to other devices or features as shown in the figures. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figures. For example, if the device in the drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.
[0074] In addition to the above, it should be noted that references to "one embodiment," "another embodiment," "an embodiment," and the like in this specification refer to specific features, structures, or characteristics described in conjunction with that embodiment as included in at least one embodiment generally described in this application. The appearance of the same expression in multiple places in the specification does not necessarily refer to the same embodiment. Furthermore, when a specific feature, structure, or characteristic is described in conjunction with any embodiment, it is intended that such feature, structure, or characteristic, when implemented in conjunction with other embodiments, also falls within the scope of the present invention.
[0075] In the above embodiments, the description of each embodiment has its own focus. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.
[0076] The foregoing description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Those skilled in the art will readily appreciate that various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.
Claims
1. A reagent filling device, characterized in that: include: Base (10); a horizontal rotation assembly (20), the horizontal rotation assembly (20) being connected to the base (10); A vertical lifting assembly (30), the vertical lifting assembly (30) being connected to the horizontal rotation assembly (20), and the vertical lifting assembly (30) being movable in a vertical direction relative to the base (10); A cantilever assembly (40), the cantilever assembly (40) being connected to the vertical lifting assembly (30), the vertical lifting assembly (30) being capable of driving the cantilever assembly (40) to move in a vertical direction, and the cantilever assembly (40) being rotatably arranged relative to the vertical lifting assembly (30); There are a plurality of cantilever assemblies (40), and the plurality of cantilever assemblies (40) are staggered in a vertical direction, and the plurality of cantilever assemblies (40) are located on the same side. The cantilever assembly (40) includes a cantilever body (41), and the length of the cantilever body (41) of at least one of the plurality of cantilever assemblies (40) is greater than the length of the cantilever bodies (41) of the remaining cantilever assemblies (40). The cantilever assembly (40) is used to add the reagent in the reagent disk (1) into the reaction cup (100) in the reaction disk (2); The projection of the rotation center of the cantilever assembly (40) on the horizontal plane is located inside the reagent disk (1); The cantilever assembly (40) is located on the peripheral side of the reagent disk (1); The reagent tray (1) has multiple circles of reagent bottles (200) along its radial direction, and the reaction tray (2) has multiple circles of reaction cups (100) along its radial direction. The cantilever assembly (40) is used to add reagents in the reagent bottles (200) in each circle into the reaction cups (100) in the reaction tray (2).
2. The reagent filling device according to claim 1, characterized in that: There are multiple horizontal rotation assemblies (20), and multiple vertical lifting assemblies (30). The multiple horizontal rotation assemblies (20) and the multiple vertical lifting assemblies (30) are arranged in a one-to-one correspondence, and each cantilever assembly (40) is correspondingly provided with one horizontal rotation assembly (20) and one vertical lifting assembly (30).
3. The reagent filling device according to claim 1, characterized in that: Also includes: A lifting body (31); a first end of the lifting body (31) is connected to the horizontal rotation assembly (20), and the other end of the lifting body (31) is connected to the cantilever assembly (40), and the cantilever assembly (40) is rotated through the lifting body (31).
4. The reagent filling device according to claim 3, characterized in that: The lifting body (31) is provided with a first transmission part (32), the first transmission part (32) is arranged at a first end of the lifting body (31), and the first transmission part (32) is connected to the horizontal rotation component (20); a second transmission part (33), the second transmission part (33) being arranged at a second end of the lifting body (31), the cantilever assembly (40) being connected to the second transmission part (33); A transmission member, wherein a first end of the transmission member is connected to the first transmission part (32), and a second end of the transmission member is connected to the second transmission part (33); the horizontal rotation assembly (20) transmits power to the second transmission part (33) through the first transmission part (32) and the transmission member, so as to drive the cantilever assembly (40) to rotate.
5. The reagent filling device according to claim 4, characterized in that: The transmission member is a transmission belt (34); alternatively, the transmission member is a rack or a chain.
6. The reagent filling device according to claim 4, characterized in that: The lifting body (31) is also provided with: The transmission shaft (35) is connected to one end of the transmission shaft (35), the second transmission portion (33) is connected to the other end of the transmission shaft (35), and the cantilever assembly (40) is connected to the other end of the transmission shaft (35). The axis of the transmission shaft (35) is the rotation center of the cantilever assembly (40).
7. The reagent filling device according to claim 6, characterized in that: The transmission shaft (35) comprises: A first transmission shaft (351) and a second transmission shaft (352), wherein the length of the first transmission shaft (351) is greater than the length of the second transmission shaft (352).
8. The reagent filling device according to claim 4, characterized in that: The horizontal rotation assembly (20) comprises: a first driving portion (211), the first driving portion (211) being connected to the base (10); A drive shaft is connected to the first drive portion (211), the first transmission portion (32) is sleeved on the outer circumference of the drive shaft, and the first drive portion (211) is used to drive the drive shaft to rotate, so that the drive shaft drives the first transmission portion (32) to rotate.
9. The reagent filling device according to claim 8, characterized in that: The drive shaft is a ball spline shaft (212).
10. The reagent filling device according to claim 4, characterized in that: The lifting body (31) is provided with an assembly hole (39), and the assembly hole (39) is located between the first transmission part (32) and the second transmission part (33).
11. The reagent filling device according to claim 10, characterized in that: The vertical lifting assembly (30) comprises: a second driving portion (36), the second driving portion (36) being connected to the base (10); a ball screw (37), the ball screw (37) being connected to the second driving portion (36); The screw nut (38) is sleeved on the outer peripheral side of the ball screw (37) and connected to the assembly hole (39). The second driving part (36) can drive the lifting body (31) to drive the cantilever assembly (40) to move in the vertical direction.
12. The reagent filling device according to claim 8, characterized in that: The first transmission part (32) comprises: A first sleeve (321), the first sleeve (321) is connected to the lifting body (31), the transmission member is connected to the first sleeve (321), and the first sleeve (321) is rotatably arranged relative to the lifting body (31).
13. The reagent filling device according to claim 12, characterized in that: The first sleeve (321) is sleeved on the drive shaft.
14. The reagent filling device according to claim 12, characterized in that: A second sleeve (322) is fixedly provided on the outer peripheral surface of the first sleeve (321); the first sleeve (321) is connected to the lifting body (31) through the second sleeve (322); one end of the second sleeve (322) is connected to the transmission member; the first sleeve (321) and the second sleeve (322) are rotatably provided relative to the lifting body (31).
15. The reagent filling device according to claim 14, characterized in that: On the outer peripheral surface of the second sleeve (322), engagement teeth are provided for cooperating with the transmission member.
16. The reagent filling device according to claim 6, characterized in that: The second transmission part (33) includes: A transmission disc (331), the transmission disc (331) is movably connected to the lifting body (31), the transmission disc (331) is connected to the transmission shaft (35), and the transmission disc (331) can drive the transmission shaft (35) to rotate.
17. The reagent filling device according to claim 16, characterized in that: On the outer peripheral surface of the transmission disc (331), engagement teeth are provided for cooperating with the transmission member.
18. The reagent filling device according to claim 6, characterized in that: The first end of the cantilever body (41) is connected to the transmission shaft (35), and the cantilever assembly (40) further includes: An anti-collision mechanism (42), the anti-collision mechanism (42) is connected to the second end of the cantilever body (41); A reagent needle (43), the reagent needle (43) is connected to the anti-collision mechanism (42).
19. The reagent filling device according to claim 1, characterized in that: The multi-loop reagent bottle (200) includes at least two loops of reagent bottles, the two loops of reagent bottles include an inner loop reagent bottle and an outer loop reagent bottle, the multi-loop reaction cup (100) includes at least two loops of reaction cups, the two loops of reaction cups include an inner loop reaction cup and an outer loop reaction cup, the cantilever assembly (40) includes a first cantilever assembly (44) and a second cantilever assembly (45), and the length of the cantilever body (41) of the first cantilever assembly (44) is greater than the length of the cantilever body (41) of the second cantilever assembly (45), the first cantilever assembly (44) is used to add the reagent in the inner loop reagent bottle to at least one of the inner loop reaction cup and the outer loop reaction cup, and the second cantilever assembly (45) is used to add the reagent in the outer loop reagent bottle to at least one of the inner loop reaction cup and the outer loop reaction cup; Alternatively, the first cantilever assembly (44) is used to add the reagent in the outer loop reagent bottle to at least one of the inner loop reaction cup and the outer loop reaction cup, and the second cantilever assembly (45) is used to add the reagent in the inner loop reagent bottle to at least one of the inner loop reaction cup and the outer loop reaction cup.
20. The reagent filling device according to claim 19, characterized in that: The rotation angle a of the first cantilever assembly (44) satisfies: 0 < a ≤ 120°, and / or, the rotation angle b of the second cantilever assembly (45) satisfies: 0 < b ≤ 90°.
21. The reagent filling device according to claim 20, characterized in that: The vertical lifting assembly (30) further includes a support shaft sleeve (47), and the support shaft sleeve (47) is used to support the first cantilever assembly (44).
22. A sample analyzer, comprising a reagent filling device (3), characterized in that: The reagent adding device (3) is the reagent adding device according to any one of claims 1 to 21.
23. The sample analyzer according to claim 22, wherein: The sample analyzer includes a plurality of reagent trays (1) and reagent adding devices (3) provided corresponding to the plurality of reagent trays (1) one by one.
Citation Information
Patent Citations
Reagent filling device and sample analyzer
CN215641321U
Dispensation mechanism for automatic chemical analyzer
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Automatic analyzing device
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