Filtering method for triple quadrupole mass spectrometer system signals

Abstract

The present invention provides a filtering processing method for a triple quadrupole mass spectrometer system signal. The method obtains noise information of the triple quadrupole mass spectrometer system in a non-operating state and an operating state to obtain fixed noise frequency distribution information and self-oscillation noise frequency distribution information of the mass spectrometer system; and uses the above two noise frequency distribution information to perform correction filtering processing on the detection signal of the first mass spectrometer detection operation; and then adjusts the sample detection time of the next mass spectrometer detection operation of the mass spectrometer system according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering processing. In this way, the detection signal output by the mass spectrometer system can be synchronously filtered for self-oscillation interference noise and environmental interference noise. By adjusting the sample detection time of the mass spectrometer system, comprehensive and accurate sample mass spectrometry detection can be ensured in the shortest time, and noise interference in the mass spectrometry detection result can be reduced, thereby improving the detection accuracy and reliability of the mass spectrometer.

Description

Technical Field

[0001] The present invention relates to the technical field of mass spectrometer signal processing, and in particular to a filtering processing method for triple quadrupole mass spectrometer system signals. Background Art

[0002] Triple quadrupole mass spectrometers have the characteristics of high sensitivity, fast analysis speed and low sample consumption, and are widely used in the fields of medicine and bioanalysis. After the sample is ionized by electrospray, it enters the multiple detection channels of the triple quadrupole mass spectrometer for mass spectrometry analysis. This allows for simultaneous detection and analysis of different components of the sample, thereby achieving multi-channel analysis of the sample. The circuit board of the ion detector of the triple quadrupole mass spectrometer can convert the ion current corresponding to the sample ion into a counting pulse signal, thereby generating a corresponding detection signal. The circuit board of the triple quadrupole mass spectrometer has self-oscillation interference noise inside the circuit board, and the external environment will generate corresponding environmental interference noise during the operation of the circuit board. These noises will inevitably interfere with the detection signal output by the circuit board, thereby reducing the detection accuracy and reliability of the mass spectrometer. Summary of the Invention

[0003] In response to the defects of the prior art, the present invention provides a filtering processing method for a triple quadrupole mass spectrometer system signal, which obtains noise information of the triple quadrupole mass spectrometer system in a non-working state and a working state to obtain fixed noise frequency distribution information and self-oscillation noise frequency distribution information of the mass spectrometer system; and uses the above two noise frequency distribution information to perform correction filtering processing on the detection signal of the first mass spectrometry detection operation; then, according to the signal frequency distribution range of the pre-processed detection signal after the correction filtering processing, the sample detection time of the next mass spectrometry detection operation of the mass spectrometer system is adjusted, so that the detection signal output by the mass spectrometer system can be synchronously filtered for self-oscillation interference noise and environmental interference noise, and by adjusting the sample detection time of the mass spectrometer system, it is ensured that comprehensive and accurate sample mass spectrometry detection can be performed in the shortest time, and the noise interference of the mass spectrometry detection result can be reduced, thereby improving the detection accuracy and reliability of the mass spectrometer.

[0004] The present invention provides a method for filtering and processing signals of a triple quadrupole mass spectrometer system, which comprises the following steps:

[0005] Step S1, obtaining first noise information of a triple quadrupole mass spectrometer system in a non-operating state and second noise information of a triple quadrupole mass spectrometer system in an operating state; determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system based on the first noise information; and determining self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system based on the second noise information;

[0006] Step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system during the first mass spectrometry detection operation, and amplifying and compensating the detection signal to obtain a preprocessed detection signal; performing correction filtering on the preprocessed detection signal according to the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information;

[0007] Step S3 , adjusting the sample detection time of the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system according to the signal frequency distribution range of the pre-processed detection signal after the correction and filtering processing.

[0008] Furthermore, in step S1, obtaining first noise information of the triple quadrupole mass spectrometer system in a non-operating state and second noise information of the triple quadrupole mass spectrometer system in an operating state specifically includes:

[0009] When the triple quadrupole mass spectrometer system is in a power-off state for a preset time length, obtaining environmental interference noise information of an external environment in which the mass spectrometer system is located, and using the information as the first noise information;

[0010] When the triple quadrupole mass spectrometer system is powered on for a preset time, self-oscillation noise information from active devices in a circuit board of the mass spectrometer system is obtained as the second noise information.

[0011] Furthermore, in step S1, determining the intrinsic noise frequency distribution information of the triple quadrupole mass spectrometer system according to the first noise information specifically includes:

[0012] Extracting a noise peak contained in a noise spectrum corresponding to the environmental interference noise information, and determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system according to the frequency corresponding to the noise peak;

[0013] as well as,

[0014] In the step S1, determining the self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system according to the second noise information specifically includes:

[0015] The self-oscillation noise peak contained in the noise spectrum corresponding to the self-oscillation noise information is extracted, and the peak frequency corresponding to the self-oscillation noise peak is determined as the self-oscillation noise frequency distribution information.

[0016] Furthermore, in step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system during the first mass spectrometry detection operation, and amplifying and compensating the detection signal to obtain a preprocessed detection signal specifically includes:

[0017] When the triple quadrupole mass spectrometer system switches from a power-off state to a power-on state and is triggered to perform a mass spectrometry detection operation for the first time, firstly clearing data from a storage element of the mass spectrometer system, then performing the first mass spectrometry detection operation and outputting a corresponding detection signal;

[0018] The detection signal is sequentially input into an operational amplifier circuit and a differential circuit, so as to perform amplification preprocessing and differential compensation preprocessing on the detection signal, thereby obtaining a preprocessed detection signal.

[0019] Furthermore, in step S2, performing correction filtering on the preprocessed detection signal according to the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information specifically includes:

[0020] Step S201: extract the noise component amplitude corresponding to the preset frequency f from the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information, and use the following formula (1) to obtain the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise:

[0021]

[0022] In the above formula (1), represents the weighted frequency value corresponding to the fixed noise and the self-oscillation noise; D(f) represents the noise component amplitude corresponding to the preset frequency f extracted from the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information; f max Indicates the frequency value corresponding to when the amplitude of the noise component in the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information decays to 0;

[0023] Step S202: Using the following formula (2), according to the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise, obtain the frequency limit value corresponding to the correction filtering process of the pre-processed detection signal.

[0024]

[0025] In the above formula (2), f0 represents the frequency limit value corresponding to the correction filtering process performed on the pre-processed detection signal; Indicates that the value of the preset frequency f is changed from 0 to f max The frequency value corresponding to the maximum value of D(f) in the process;

[0026] Step S203 : removing the signal components with a frequency less than or equal to f0 in the pre-processed detection signal, thereby achieving the correction filtering process.

[0027] Furthermore, in step S3, adjusting the sample detection time of the triple quadrupole mass spectrometer system for the next mass spectrometry detection operation according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering process specifically includes:

[0028] Step S301: extract the maximum signal frequency value f of the pre-processed detection signal from the signal frequency distribution range of the pre-processed detection signal after the correction filtering process. a_max , and using the following formula (3), we can get the power supply duration of the triple quadrupole mass spectrometer system in the next mass spectrometry detection operation,

[0029]

[0030] In the above formula (3), T1 represents the duration of power supply of the triple quadrupole mass spectrometer system in the next mass spectrometry detection operation; T represents the preset power supply reference time length; D(f a ) indicates that the frequency of the preprocessed detection signal is f a The corresponding signal component amplitude; Indicates that the frequency f a The value ranges from 0 to f a_max During the process D(f a ) is the frequency value corresponding to the maximum value;

[0031] Step S302 : adjusting the sample detection time length of the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system to T1 .

[0032] Further, during the next mass spectrometry detection operation performed by the triple quadrupole mass spectrometer system, a detection signal corresponding to the mass spectrometry detection operation is obtained, and a signal-to-noise ratio of the detection signal is determined;

[0033] When the signal-to-noise ratio is less than or equal to a preset signal-to-noise ratio threshold, the detection signal of this mass spectrometry detection operation is determined to be an invalid detection signal.

[0034] Furthermore, after step S303, the following step S304 is also included:

[0035] When it is determined that the detection signal of this mass spectrometry detection operation is an invalid detection signal, the triple quadrupole mass spectrometer system is powered off and restarted, and the above steps S1 to S3 are repeated.

[0036] Compared with the existing technology, the filtering processing method for the triple quadrupole mass spectrometer system signal obtains the noise information of the triple quadrupole mass spectrometer system in the non-working state and the working state to obtain the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information of the mass spectrometer system; and uses the above two noise frequency distribution information to perform correction filtering processing on the detection signal of the first mass spectrometry detection operation; and then adjusts the sample detection time of the next mass spectrometry detection operation of the mass spectrometer system according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering processing, so that the detection signal output by the mass spectrometer system can be synchronously filtered for self-oscillation interference noise and environmental interference noise, and by adjusting the sample detection time of the mass spectrometer system, it can be ensured that comprehensive and accurate sample mass spectrometry detection is performed in the shortest time, and the noise interference of the mass spectrometry detection result is reduced, thereby improving the detection accuracy and reliability of the mass spectrometer.

[0037] Other features and advantages of the present invention will be described in the following description, and in part will become apparent from the description, or will be understood by practicing the present invention. The purposes and other advantages of the present invention can be realized and obtained by the structures particularly pointed out in the written description, claims, and drawings.

[0038] The technical solution of the present invention is further described in detail below through the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0040] Figure 1 The present invention provides a flow chart of a method for filtering and processing signals of a triple quadrupole mass spectrometer system. DETAILED DESCRIPTION

[0041] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0042] See Figure 1, is a flow chart of a method for filtering and processing signals of a triple quadrupole mass spectrometer system provided by an embodiment of the present invention. The method for filtering and processing signals of a triple quadrupole mass spectrometer system comprises the following steps:

[0043] Step S1, obtaining first noise information of a triple quadrupole mass spectrometer system in a non-operating state and second noise information of a triple quadrupole mass spectrometer system in an operating state; determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system based on the first noise information; and determining self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system based on the second noise information;

[0044] Step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system during the first mass spectrometry detection operation, and performing amplification and compensation preprocessing on the detection signal to obtain a preprocessed detection signal; performing correction and filtering processing on the preprocessed detection signal based on the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information;

[0045] Step S3 , adjusting the sample detection time of the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system according to the signal frequency distribution range of the pre-processed detection signal after the correction filtering process.

[0046] The beneficial effects of the above technical solution are as follows: the filtering processing method for the triple quadrupole mass spectrometer system signal obtains the noise information of the triple quadrupole mass spectrometer system in the non-working state and the working state to obtain the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information of the mass spectrometer system; and uses the above two noise frequency distribution information to perform correction filtering processing on the detection signal of the first mass spectrometry detection operation; and then adjusts the sample detection time of the next mass spectrometry detection operation of the mass spectrometer system according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering processing, so that the detection signal output by the mass spectrometer system can be synchronously filtered for self-oscillation interference noise and environmental interference noise, and by adjusting the sample detection time of the mass spectrometer system, it can be ensured that a comprehensive and accurate sample mass spectrometry detection is performed in the shortest time, and the noise interference of the mass spectrometry detection results is reduced, thereby improving the detection accuracy and reliability of the mass spectrometer.

[0047] Preferably, in step S1, obtaining first noise information of the triple quadrupole mass spectrometer system in a non-operating state and second noise information of the triple quadrupole mass spectrometer system in an operating state specifically includes:

[0048] When the triple quadrupole mass spectrometer system is in a power-off state for a preset time length, obtaining environmental interference noise information of an external environment in which the mass spectrometer system is located as the first noise information;

[0049] When the triple quadrupole mass spectrometer system is in a power-on state for a preset time, self-oscillation noise information from active devices in a circuit board of the mass spectrometer system is obtained as the second noise information.

[0050] The beneficial effects of the above technical solution are as follows: the triple quadrupole mass spectrometer system is subject to electromagnetic interference from the external environment, which generates corresponding environmental interference noise information in the detection signal; and the active devices on the circuit board of the triple quadrupole mass spectrometer system generate self-oscillation noise information during the passage. These two types of noise information can interfere with the detection results during the mass spectrometer system's mass spectrometry detection process. By obtaining these two types of noise information, it is possible to facilitate the subsequent effective filtering of the mass spectrometer system's detection results.

[0051] Preferably, in step S1, determining the intrinsic noise frequency distribution information of the triple quadrupole mass spectrometer system according to the first noise information specifically includes:

[0052] Extracting a noise peak from a noise spectrum corresponding to the environmental interference noise information, and determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system based on the frequency corresponding to the noise peak;

[0053] as well as,

[0054] In step S1, determining the self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system according to the second noise information specifically includes:

[0055] The self-oscillation noise peak contained in the noise spectrum corresponding to the self-oscillation noise information is extracted, and the peak frequency corresponding to the self-oscillation noise peak is determined as the self-oscillation noise frequency distribution information.

[0056] The beneficial effect of the above technical solution is that the distribution of noise frequencies in the noise spectrum of the environmental interference noise information and the self-oscillation noise information directly affects the degree of interference of the noise information on the detection result. The closer the noise frequency in the noise spectrum is to the detection signal frequency in the detection spectrum of the detection result, the greater the interference of the noise information on the detection result. By determining the intrinsic noise frequency distribution information and the self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system, it is easy to accurately remove the noise components present in the detection signal, thereby maximizing the signal-to-noise ratio of the detection signal.

[0057] Preferably, in step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system when performing a mass spectrometry detection operation for the first time, and amplifying and compensating the detection signal to obtain a preprocessed detection signal specifically includes:

[0058] When the triple quadrupole mass spectrometer system switches from a power-off state to a power-on state and is triggered to perform a mass spectrometry detection operation for the first time, firstly clearing data from a storage element of the mass spectrometer system, then performing the first mass spectrometry detection operation and outputting a corresponding detection signal;

[0059] The detection signal is sequentially input into an operational amplifier circuit and a differential circuit, so as to perform amplification preprocessing and differential compensation preprocessing on the detection signal, thereby obtaining a preprocessed detection signal.

[0060] The beneficial effect of the above technical solution is that when the triple quadrupole mass spectrometer system switches from a powered-on state to a powered-on state and is triggered to perform its first mass spectrometry detection operation, data is first cleared from the mass spectrometer system's storage elements, thereby preventing crosstalk in the mass spectrometer system's detection results. Furthermore, amplification and differential compensation preprocessing of the detection signal improves the signal processability, facilitating the accuracy and effectiveness of subsequent noise filtering of the detection signal.

[0061] Preferably, in step S2, performing correction filtering on the pre-processed detection signal according to the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information specifically includes:

[0062] Step S201: extract the noise component amplitude corresponding to the preset frequency f from the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information, and use the following formula (1) to obtain the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise:

[0063]

[0064] In the above formula (1), represents the weighted frequency value corresponding to the fixed noise and the self-oscillation noise; D(f) represents the noise component amplitude corresponding to the preset frequency f extracted from the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information; f max Indicates the frequency value corresponding to when the amplitude of the noise component in the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information decays to 0;

[0065] Step S202: Using the following formula (2), according to the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise, the frequency limit value corresponding to the correction filtering process of the pre-processed detection signal is obtained.

[0066]

[0067] In the above formula (2), f0 represents the frequency limit value corresponding to the correction filtering process of the pre-processed detection signal; Indicates that the value of the preset frequency f is changed from 0 to f maxThe frequency value corresponding to the maximum value of D(f) in the process;

[0068] Step S203 , removing the signal components with a frequency less than or equal to f0 in the pre-processed detection signal, thereby implementing the correction filtering process.

[0069] The beneficial effects of the above technical solution are as follows: using the above formula (1), according to the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information, the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise are obtained, and then reasonable automatic analysis is performed through the weighted frequency values ​​to lay the foundation for subsequent filtering; then using the above formula (2), according to the weighted frequency values ​​corresponding to the fixed noise and the self-oscillation noise, the frequency limit value currently required for filtering is obtained, and then the most appropriate frequency limit value is selected through comparison for filtering, which can not only ensure the comprehensiveness of the filtering, but also filter out the frequency of the maximum signal interference, thereby ensuring the reliability of the filtering.

[0070] Preferably, in step S3, adjusting the sample detection time of the triple quadrupole mass spectrometer system for the next mass spectrometry detection operation according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering process specifically includes:

[0071] Step S301: extract the maximum signal frequency value f of the pre-processed detection signal from the signal frequency distribution range of the pre-processed detection signal after the correction filtering process. a_max , and using the following formula (3), we can get the power supply duration of the triple quadrupole mass spectrometer system in the next mass spectrometry detection operation,

[0072]

[0073] In the above formula (3), T1 represents the duration of power supply of the triple quadrupole mass spectrometer system in the next mass spectrometry detection operation; T represents the preset power supply reference time length; D(f a ) indicates that the frequency of the preprocessed detection signal is f a The corresponding signal component amplitude; Indicates that the frequency f a The value ranges from 0 to f a_max During the process D(f a ) is the frequency value corresponding to the maximum value;

[0074] Step S302 : adjusting the sample detection time length of the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system to T1 .

[0075] The beneficial effects of the above technical solution are: using the above formula (3) to control the sample detection time of the next mass spectrometry detection operation according to the waveform frequency range generated by the triple quadrupole mass spectrometer, and then when the signal amplitude generated by the triple quadrupole mass spectrometer is large, the noise acquisition time of the triple quadrupole mass spectrometer is not excessively increased to increase the operating frequency of the system and save working time; when the signal amplitude generated by the triple quadrupole mass spectrometer is small, by extending the noise acquisition time, the noise situation can be further analyzed to perform more detailed filtering, thereby ensuring the reliability of the filtering.

[0076] Preferably, after step S302, the following step S303 is further included:

[0077] During the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system, obtaining a detection signal corresponding to the mass spectrometry detection operation and determining a signal-to-noise ratio of the detection signal;

[0078] When the signal-to-noise ratio is less than or equal to a preset signal-to-noise ratio threshold, the detection signal of this mass spectrometry detection operation is determined to be an invalid detection signal.

[0079] The beneficial effect of the above technical solution is: when the triple quadrupole mass spectrometer system performs the next mass spectrometry detection operation to obtain a detection signal, if the signal-to-noise ratio of the detection signal is less than or equal to the preset signal-to-noise ratio threshold, it means that the detection result of this mass spectrometry detection operation has a large interference error. At this time, the detection signal is determined to be an invalid detection signal and the signal is cleared, which can prevent the invalid detection signal from affecting the accuracy of the output result of the mass spectrometer system.

[0080] Preferably, after step S303, the following step S304 is further included:

[0081] When it is determined that the detection signal of this mass spectrometry detection operation is an invalid detection signal, the triple quadrupole mass spectrometer system is powered off and restarted, and the above steps S1 to S3 are repeated.

[0082] The beneficial effect of the above technical solution is: when it is determined that the detection signal of this mass spectrometry detection operation is determined to be an invalid detection signal, the triple quadrupole mass spectrometer system is powered off and restarted, and the above steps S1-S3 are repeated. In this way, when a detection error occurs in the triple quadrupole mass spectrometer system, reset and correction can be performed, thereby improving the detection accuracy and reliability of the mass spectrometer.

[0083] It can be seen from the contents of the above embodiments that the filtering processing method for the triple quadrupole mass spectrometer system signal obtains the noise information of the triple quadrupole mass spectrometer system in the non-working state and the working state to obtain the fixed noise frequency distribution information and the self-oscillation noise frequency distribution information of the mass spectrometer system; and uses the above two noise frequency distribution information to perform correction filtering processing on the detection signal of the first mass spectrometry detection operation; and then adjusts the sample detection time of the next mass spectrometry detection operation of the mass spectrometer system according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering processing, so that the detection signal output by the mass spectrometer system can be synchronously filtered for self-oscillation interference noise and environmental interference noise, and by adjusting the sample detection time of the mass spectrometer system, it can be ensured that a comprehensive and accurate sample mass spectrometry detection is performed in the shortest time, and the noise interference of the mass spectrometry detection results is reduced, thereby improving the detection accuracy and reliability of the mass spectrometer.

[0084] Obviously, those skilled in the art may make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if such changes and modifications fall within the scope of the claims and their equivalents, the present invention is intended to include such changes and modifications.

Claims

1. A method for filtering signals of a triple quadrupole mass spectrometer system, characterized in that: It includes the following steps: Step S1, obtaining first noise information of a triple quadrupole mass spectrometer system in a non-operating state and second noise information of a triple quadrupole mass spectrometer system in an operating state; determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system based on the first noise information; and determining self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system based on the second noise information; Step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system during the first mass spectrometry detection operation, and amplifying and compensating the detection signal to obtain a preprocessed detection signal; performing correction filtering on the preprocessed detection signal according to the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information; Step S3, adjusting the sample detection time of the triple quadrupole mass spectrometer system for the next mass spectrometry detection operation according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering process; Wherein, in the step S2, performing correction filtering processing on the pre-processed detection signal according to the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information specifically includes: Step S201: extract the noise component amplitude corresponding to the preset frequency f from the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information, and use the following formula (1) to obtain the weighted frequency values ​​corresponding to the inherent noise and the self-oscillation noise: （1） In the above formula (1), Indicates the weighted frequency value corresponding to the inherent noise and self-oscillation noise; Indicates the noise component amplitude corresponding to the preset frequency f extracted from the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information; Indicates the frequency value corresponding to when the amplitude of the noise component in the inherent noise frequency distribution information and the self-oscillation noise frequency distribution information decays to 0; Step S202: Using the following formula (2), according to the weighted frequency values ​​corresponding to the inherent noise and the self-oscillation noise, obtain the frequency limit value corresponding to the correction filtering process of the pre-processed detection signal. （2） In the above formula (2), Indicates the frequency limit value corresponding to the correction filtering process performed on the pre-processed detection signal; Indicates that the value of the preset frequency f is changed from 0 to In the process The frequency value corresponding to the maximum value; Step S203: The frequency of the pre-processed detection signal is less than or equal to The signal components are removed, thereby realizing the correction filtering processing.

2. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 1, wherein: In step S1, obtaining first noise information of the triple quadrupole mass spectrometer system in a non-operating state and second noise information of the triple quadrupole mass spectrometer system in an operating state specifically includes: When the triple quadrupole mass spectrometer system is in a power-off state for a preset time length, obtaining environmental interference noise information of an external environment in which the mass spectrometer system is located, and using the information as the first noise information; When the triple quadrupole mass spectrometer system is powered on for a preset time, self-oscillation noise information from active devices in a circuit board of the mass spectrometer system is obtained as the second noise information.

3. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 2, wherein: In the step S1, determining the intrinsic noise frequency distribution information of the triple quadrupole mass spectrometer system according to the first noise information specifically includes: Extracting a noise peak contained in a noise spectrum corresponding to the environmental interference noise information, and determining inherent noise frequency distribution information of the triple quadrupole mass spectrometer system according to the frequency corresponding to the noise peak; as well as, In the step S1, determining the self-oscillation noise frequency distribution information of the triple quadrupole mass spectrometer system according to the second noise information specifically includes: The self-oscillation noise peak contained in the noise spectrum corresponding to the self-oscillation noise information is extracted, and the peak frequency corresponding to the self-oscillation noise peak is determined as the self-oscillation noise frequency distribution information.

4. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 3, wherein: In step S2, obtaining a detection signal output by the triple quadrupole mass spectrometer system during the first mass spectrometry detection operation, and amplifying and compensating the detection signal to obtain a preprocessed detection signal specifically includes: When the triple quadrupole mass spectrometer system switches from a power-off state to a power-on state and is triggered to perform a mass spectrometry detection operation for the first time, firstly clearing data from a storage element of the mass spectrometer system, then performing the first mass spectrometry detection operation and outputting a corresponding detection signal; The detection signal is sequentially input into an operational amplifier circuit and a differential circuit, so as to perform amplification preprocessing and differential compensation preprocessing on the detection signal, thereby obtaining a preprocessed detection signal.

5. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 1, wherein: In step S3, adjusting the sample detection time of the triple quadrupole mass spectrometer system for the next mass spectrometry detection operation according to the signal frequency distribution range of the preprocessed detection signal after the correction filtering process specifically includes: Step S301: extract the maximum signal frequency value of the pre-processed detection signal from the signal frequency distribution range of the pre-processed detection signal after the correction filtering process. , and using the following formula (3), we can get the power supply duration of the triple quadrupole mass spectrometer system during the next mass spectrometry detection operation: （3） In the above formula (3), Indicates the duration of power supply for the triple quadrupole mass spectrometer system before the next mass spectrometry detection operation; Indicates the preset power supply reference time length; Indicates that the frequency of the preprocessed detection signal is The corresponding signal component amplitude; Indicates that the frequency The value ranges from 0 to In the process The frequency value corresponding to the maximum value; Step S302: Adjust the sample detection time length of the next mass spectrometry detection operation of the triple quadrupole mass spectrometer system to .

6. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 5, wherein: After step S302, the following step S303 is also included: During the next mass spectrometry detection operation performed by the triple quadrupole mass spectrometer system, obtaining a detection signal corresponding to the mass spectrometry detection operation, and determining a signal-to-noise ratio of the detection signal; When the signal-to-noise ratio is less than or equal to a preset signal-to-noise ratio threshold, the detection signal of this mass spectrometry detection operation is determined to be an invalid detection signal.

7. The method for filtering signals of a triple quadrupole mass spectrometer system according to claim 6, wherein: After step S303, the following step S304 is also included: When it is determined that the detection signal of this mass spectrometry detection operation is an invalid detection signal, the triple quadrupole mass spectrometer system is powered off and restarted, and the above steps S1 to S3 are repeated.

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