A refractive correction implant

Abstract

The application discloses a refractive correction implant, which is used for implanting into an anterior chamber of a human eye and comprises a lens body, a connecting part and a fitting part, the fitting part is used for being adsorbed to an inner wall of a cornea of the human body, the lens body is used for correcting the refractive of the eye, the lens body is located at a middle position of the inner wall of the cornea, and a gap is formed between the lens body and the inner wall of the cornea, the connecting part is located between the lens body and the fitting part and is used for connecting the lens body and the fitting part, and a through hole is formed in the connecting part and is used for allowing aqueous humor in the anterior chamber to flow through. The refractive correction implant can be used for treating refractive ophthalmic diseases such as high myopia and the like, and does not cause damage to the cornea of the human body, and is safe and reliable.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of ophthalmic treatment equipment, in particular to a refractive correction implant. BACKGROUND

[0002] For patients with refractive eye diseases, the current mainstream refractive laser surgery is an irreversible treatment scheme, which changes the vision of the patient by permanently reshaping the cornea, and can only be corrected by repeated surgery as the refractive error changes, which causes great damage to the cornea of the patient and is low in economy. At present, the only product on the market that can achieve reversible refractive error treatment effect is the ICL product implanted in the eye, that is, the lens is implanted in the eye through minimally invasive surgery, and the refractive error is corrected. Although the product does not cause damage to the cornea, the implantation position of the product is between the lens and the iris, the space is small, and it is very easy to cause pupil blockage and cause glaucoma.

[0003] Therefore, how to continuously and effectively correct the refractive error of the patient is a technical problem that needs to be solved by those skilled in the art. SUMMARY

[0004] The technical problem solved by the present application is to provide a refractive correction implant to solve the problem of low safety and easy glaucoma in the prior art.

[0005] To solve the above technical problems, the technical scheme adopted by the present application is to provide a refractive correction implant for implanting into the anterior chamber of the human eye, comprising a lens body, a connecting part and a fitting part, the fitting part is used for adsorbing to the inner wall of the cornea of the human body, the lens body is used for correcting the refractive error of the eye, the lens body is located at the middle position of the inner wall of the cornea, and there is a gap between the lens body and the inner wall of the cornea, the connecting part is located between the lens body and the fitting part and is used for connecting the lens body and the fitting part, and the connecting part is provided with a through hole for the aqueous humor in the anterior chamber to flow.

[0006] Preferably, the diameter of the lens body is 4mm-10mm.

[0007] Preferably, the diameter of the lens body is 4mm-7mm.

[0008] Preferably, the diameter of the lens body is 4mm-5mm.

[0009] Preferably, the gap between the lens body and the inner wall of the cornea is 0.5mm-1.5mm.

[0010] Preferably, the upper surface of the lens body is convex or concave, and the lower surface of the lens body is convex or concave.

[0011] Preferably, the through holes are uniformly arranged around the connecting part.

[0012] Preferably, the perforations are circular or arcuate or long strip-shaped.

[0013] Preferably, the outermost edge of the fitting portion has a distance from the outermost edge of the inner wall of the cornea.

[0014] Preferably, the material of the refractive correction implant is collagen polymer or silicone or acrylic or hydrogel.

[0015] The present application has the beneficial effect that the present application discloses a refractive correction implant for implanting into the anterior chamber of the human eye, the refractive correction implant comprising a lens body, a connecting portion and a fitting portion, the fitting portion being used for adsorbing to the inner wall of the cornea of the human body, the lens body being used for refractive correction of the eye, the lens body being located at the middle position of the inner wall of the cornea, and the lens body having a gap from the inner wall of the cornea, the connecting portion being located between the lens body and the fitting portion and being used for connecting the lens body and the fitting portion, and the connecting portion being provided with perforations for the circulation of aqueous humor in the anterior chamber. The refractive correction implant can treat refractive ophthalmic diseases including high myopia and the like, and will not cause damage to the human cornea, and is safe and reliable. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is a schematic diagram of an embodiment of the refractive correction implant of the present application;

[0017] Figure 2 is Figure 1 is a top view schematic diagram (shielding the cornea) of the embodiment shown;

[0018] Figure 3 is a schematic diagram of another embodiment of the refractive correction implant of the present application;

[0019] Figure 4 is Figure 3 is a top view schematic diagram (shielding the cornea) of the embodiment shown. DETAILED DESCRIPTION

[0020] In order to facilitate the understanding of the present application, the present application will be described in more detail below in conjunction with the drawings and specific embodiments. The preferred embodiments of the present application are shown in the drawings. However, the present application can be realized in many different forms and is not limited to the embodiments described in the specification. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present application more thorough and comprehensive.

[0021] It should be noted that unless otherwise defined, all technical and scientific terms used in the specification are the same as those commonly understood by those skilled in the art of the present application. The terms used in the specification of the present application are only for the purpose of describing the specific embodiments and are not intended to limit the present application.

[0022] BRIEF DESCRIPTION OF DRAWINGS: The arrows in the drawings indicate the direction of aqueous humor flow.

[0023] In combination Figure 1 and Figure 2 The refractive correction implant, for implanting into the anterior chamber 4 of the human eye, in actual operation, the refractive correction implant is implanted into the anterior chamber 4 of the patient's eye between the cornea 5 and the iris 6, i.e. the refractive correction implant is implanted into the anterior chamber 4 of the patient's eye through the limbus 7, after the refractive correction implant is unfolded in the anterior chamber 4, it will be adsorbed to the inner wall 51 of the cornea, the lens part (i.e. the lens body 1) of the refractive correction implant improves the performance of the patient's refractive system, achieving the purpose of refractive correction, the refractive power of the lens body 1 is customized according to the patient's vision condition to ensure the accuracy of refractive correction.

[0024] Preferably, the refractive correction implant includes a lens body 1, a connecting part 2 and a fitting part 3, the fitting part 3 is used to be adsorbed to the inner wall 51 of the cornea of the human body, the lens body 1 is used to correct the refractive of the eye, the lens body 1 is located at the middle position of the inner wall 51 of the cornea, i.e. the lens body 1 will cover most of the central visual field of the patient to ensure the effect of refractive correction, and there is a gap between the lens body 1 and the inner wall 51 of the cornea, which can make the aqueous humor enter the gap between the refractive correction implant and the inner wall 51 of the cornea to provide oxygen and nutrients for the endothelial cells at the middle position of the cornea, maintain the normal survival and work of the endothelial cells in the central cornea, the connecting part 2 is located between the lens body 1 and the fitting part 3 and is used to connect the lens body 1 and the fitting part 3, the fitting part 3 is closely fitted with the inner wall 51 of the cornea, providing structural support for the implant, ensuring that the lens body 1 is firmly fixed in the anterior chamber 4 due to the adsorption of the fitting part 3, to maintain the relative stability of the middle position of the cornea 51, thereby ensuring the accuracy of refractive correction, the connecting part 2 is provided with a perforation 21 for the circulation of the aqueous humor in the anterior chamber 4, ensuring that the aqueous humor can flow through the perforation 21 to the gap between the lens body 1 and the inner wall 51 of the cornea, providing oxygen and nutrients for the endothelial cells of the cornea.

[0025] Preferably, the thickness of the lens body 1 is in the range of 100 microns-4 millimeters, further preferably, the thickness of the lens body 1 is in the range of 100 microns-1 millimeter, further preferably, the thickness of the lens body 1 is in the range of 100 microns-700 microns.

[0026] Preferably, the thickness of the lens body 1 is in the range of 700 microns-3 millimeters, further preferably, the thickness of the lens body 1 is in the range of 700 microns-1 millimeter.

[0027] Preferably, the diameter of the lens body 1 is in the range of 4mm-10mm, ensuring that the lens body can completely cover the central area of the cornea to ensure the effect of refractive correction.

[0028] Further preferably, the diameter of the lens body 1 ranges from 4mm to 7mm.

[0029] Further preferably, the diameter of the lens body 1 ranges from 4mm to 5mm.

[0030] Preferably, the width of the fitting portion 3 ranges from 1mm to 5mm, and further preferably, the width of the fitting portion 3 ranges from 1mm to 3mm.

[0031] Preferably, the gap X1 between the lens body 1 and the inner wall of the cornea 51 ranges from 0.5mm to 1.5mm, which ensures that there is a gap for the aqueous humor to flow and deliver nutrients and oxygen, and also ensures that the gap is not too large to guarantee the effect of refractive correction.

[0032] Preferably, the upper surface of the lens body 1 is convex or concave, the lower surface of the lens body 1 is convex or concave, and the curvature of the upper and lower surfaces of the lens body 1 is designed according to the requirements of refractive correction, and the thickness of the lens body 1 is selected and designed according to the refractive error of the patient, which is not described here.

[0033] Preferably, the perforations 21 are uniformly arranged around the connecting portion 2, which ensures that the aqueous humor uniformly flows into the gap between the lens body 1 and the inner wall of the cornea 51, so that oxygen and nutrients can be uniformly and quickly delivered to the corneal endothelial cells, and the normal circulation of the aqueous humor is ensured.

[0034] Preferably, the perforations 21 are circular or arc-shaped or strip-shaped.

[0035] Preferably, there is a distance X2 between the outermost edge of the fitting portion 3 and the outermost edge of the inner wall of the cornea 51, i.e. the fitting portion 3 does not completely cover the outermost edge of the inner wall of the cornea 51, which is to leave space for subsequent surgical operations, and at the same time to protect the trabecular meshwork at the position of the limbus 7 from being worn by the fitting portion 3.

[0036] The corneal endothelial cells are mainly divided into central corneal endothelial cells and peripheral corneal endothelial cells, the central corneal endothelial cells mainly rely on the aqueous humor for nourishment, and the peripheral corneal endothelial cells mainly rely on the limbus for oxygen supply, the fitting portion 3 is mainly attached to the edge of the cornea, and the fitting portion 3 does not affect the oxygen supply and metabolism of the corneal endothelial cells.

[0037] The connecting portion 2 is connected to the lens body 1 and the fitting portion 3, and the overall transition is smooth, i.e. the overall design of the refractive correction implant (hereinafter referred to as implant) adopts a smooth optical transition, the lens body 1 will be optically designed according to the vision status and needs of the patient and the angle and relative position between the lens body 1 and the cornea 5 to achieve a specific refractive error and achieve the purpose of refractive correction, and at the same time restore a smooth field of view for the patient.

[0038] Preferably, the material of the refractive correction implant is collagen polymer or silicone or acrylic or hydrogel, which is safe and non-irritating, and ensures good biocompatibility between the implant (i.e. the lens body 1, the connecting part 2 and the fitting part 3), excellent optical properties, and the material of the implant also has the properties of flexibility and foldability, which can be implanted in the folded state and automatically unfolded after being implanted in the eye, and can be smoothly refolded and taken out, without adhesion to the intraocular tissues (such as the anterior chamber, the cornea or the iris) and the formation of scars, and the material of the implant also has the properties of high oxygen permeability, which can ensure the nutrition supply of the cornea and maintain the normal metabolic function of the cornea.

[0039] Specifically, the fitting part 3 has high oxygen permeability, which does not affect the normal nutrition and oxygen absorption of the endothelial cells of the corneal inner wall 51 even if the fitting part 3 is attached to the endothelial cells, and still ensures that the endothelial cells of the cornea maintain their original cell characteristics and functions.

[0040] Preferably, in combination with Figure 3 and Figure 4 In another embodiment, the refractive correction implant (referred to as the implant) includes a lens body A1 and a fitting part A2, the lens body A1 is connected to the fitting part A2, the lens body A1 is used to attach to the middle position of the corneal inner wall A31 of the cornea A3 in the eye and form an aqueous humor barrier, the lens body A1 is used for refractive correction of the eye, and the fitting part A2 is used to adsorb and attach to the peripheral position of the corneal inner wall A31. For patients with corneal A3 damage or partial damage and at the same time with refractive errors, the implant is implanted between the iris A4 and the cornea A3 of the patient through a minimally invasive surgery (the implant is implanted through the limbus A6), the implant gradually unfolds in the anterior chamber A5 of the eye, and adsorbs and attaches to the corneal inner wall A31 of the cornea A3, to replace or partially replace the corneal endothelial cells, on the one hand to treat the corneal endothelial cells to form a corneal-aqueous humor barrier and treat corneal disease-related diseases, and on the other hand to treat refractive ophthalmic diseases including high myopia through the lens body A1 of the implant after optical design.

[0041] In actual surgery, the implant is implanted into the anterior chamber A5 of the patient's eye through the limbus A6, and after the implant is unfolded in the anterior chamber A5, it will completely adsorb on the corneal inner wall A31, and the refractive power of the lens body A1 of the implant is customized and designed according to the vision condition of the patient, which can significantly improve the refractive system performance of the patient and achieve the purpose of refractive correction.

[0042] Preferably, the implant is made of a material with good biocompatibility and excellent optical properties; the implant material also has the properties of flexibility and foldability, can realize automatic full expansion after implantation in a folded state, and can be smoothly refolded and removed from the limbus A6 without tissue adhesion and scar formation. The material of the implant also has high oxygen permeability and other properties, which can ensure the nutrition supply of the cornea A3 and maintain the normal metabolic function of the cornea A3.

[0043] Specifically, the lens body A1 of the implant completely adheres to the inner wall of the cornea A31, can play the role of cornea-aqueous barrier, replace the diseased endothelial layer (i.e. the endothelial cell layer of the cornea), hinder the transfer of liquid to the central stroma layer of the cornea, and alleviate corneal edema and other corneal diseases.

[0044] The implant as a whole adopts a smooth optical transition design, and the central lens body A1 will be optically designed according to the vision condition and needs of the patient to achieve a specific diopter and achieve the purpose of refractive correction, while restoring a smooth high-quality vision level for the patient.

[0045] The lens body A1 of the implant covers most of the central visual field of the patient to ensure the effect of refractive correction.

[0046] The fitting part A2 is smoothly connected with the lens body A1, and is adsorbed to the inner wall of the cornea A31 and its periphery after the implant is implanted and expanded.

[0047] The implant and the inner wall of the cornea A31 do not need an additional adhesive layer to improve the adsorption effect of the implant and the cornea A3, and still can realize the support for the implant.

[0048] Preferably, there is a distance L1 between the outermost edge of the fitting part A2 and the outermost edge of the inner wall of the cornea A31, that is, the fitting part A2 does not completely cover the outermost edge of the inner wall of the cornea A31, which is to leave a space for subsequent surgical operation, and to protect the trabecular meshwork at the position of the limbus A6 from being worn by the fitting part 3.

[0049] Preferably, the width of the fitting part A2 is 1mm-5mm, further preferably, the width of the fitting part A2 is 1mm-4mm, and further preferably, the width of the fitting part A2 is 1mm-3mm.

[0050] Preferably, the diameter of the lens body A1 is 4mm-10mm.

[0051] Further preferably, the diameter of the lens body A1 is 4mm-7mm.

[0052] Further preferably, the diameter of the lens body A1 is 4mm-5mm.

[0053] Preferably, the upper surface of the lens body A1 is adapted to fit the inner wall of the cornea A31, the lower surface of the lens body A1 is convex or concave, the curvature of the upper surface and the lower surface of the lens body A1 is designed according to the requirement of refractive correction, and the thickness of the lens body A1 is designed according to the refractive error of the patient, which will not be described here.

[0054] Preferably, the fitting part A2 is attached to the inner wall of the cornea A31 by electrostatic attraction or biodegradable biological adhesives, which is more environmentally friendly and safe, and has stable properties and no side effects to the patient.

[0055] Preferably, the material of the refractive correction implant is collagen polymer or silicone or acrylic acid or hydrogel, which is safer and less irritating to the patient.

[0056] Based on the above embodiments, the present application discloses a refractive correction implant for implanting into the anterior chamber of the human eye, which comprises a lens body, a connecting part and a fitting part, the fitting part is used to adsorb to the inner wall of the cornea of the human body, the lens body is used to correct the refractive error of the eye, the lens body is located at the middle position of the inner wall of the cornea, and there is a gap between the lens body and the inner wall of the cornea, the connecting part is located between the lens body and the fitting part and is used to connect the lens body and the fitting part, and the connecting part is provided with a through hole for the circulation of aqueous humor in the anterior chamber. The refractive correction implant can treat refractive ophthalmic diseases including high myopia and the like, and will not cause damage to the human cornea, which is safe and reliable.

[0057] The above is only an embodiment of the present application, and does not limit the patent scope of the present application, any equivalent structural transformation using the content of the specification and drawings, or direct or indirect application in other related technical fields, is included in the patent protection scope of the present application.

Claims

1. A refractive corrective implant for implantation in the anterior chamber of the human eye, characterized in that, include: The lens body is used to correct refractive errors in the eye. The lens body is located in the middle of the inner wall of the cornea, and there is a gap between the lens body and the inner wall of the cornea. The diameter of the lens body ranges from 4mm to 10mm. The gap between the lens body and the inner wall of the cornea ranges from 0.5mm to 1.5mm. The adhesive portion is used to adhere to the edge of the inner wall of the human cornea, providing support for the implant and ensuring that the lens body is firmly fixed in the anterior chamber due to the adsorption of the adhesive portion; there is a distance between the outermost edge of the adhesive portion and the outermost edge of the inner wall of the cornea. The connecting part has a ring-shaped structure. The connecting part is located between the lens body and the bonding part and is used to connect the lens body and the bonding part. The connecting part has perforations for the flow of aqueous humor in the anterior chamber. The perforations are evenly distributed around the connecting part.

2. The refractive correction implant according to claim 1, characterized in that, The diameter of the lens body ranges from 4mm to 7mm.

3. The refractive correction implant according to claim 1, characterized in that, The diameter of the lens body is in the range of 4mm-5mm.

4. The refractive correction implant according to claim 1, characterized in that, The upper surface of the lens body is convex or concave, and the lower surface of the lens body is convex or concave.

5. The refractive correction implant according to claim 1, characterized in that, The perforation can be circular, arc-shaped, or elongated.

6. The refractive correction implant according to claim 1, characterized in that, The refractive correction implant is made of silicone, acrylic, or hydrogel.

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