A mass spectrometer

Abstract

The present invention relates to the technical field of mass spectrometry detection instruments, and discloses a mass spectrometer, including an ion source module, an illumination module, and an imaging module. The ion source module includes an ion source cavity, an acceleration component arranged inside the ion source cavity, and a target material located below the ion source cavity. The illumination module and the imaging module are connected to the ion source cavity, and the acceleration component is not located on the light path of the illumination light emitted by the illumination module, so as to prevent the acceleration component from blocking the sample, and to prevent the acceleration component from forming projections, reflections, etc. on the target material, which may cause the problem of blurred sample imaging, so that the imaging module only captures the image of the sample on the target material, so that the imaging is clear, there is no environmental noise, and the imaging effect is good. In addition, a filter is provided between the camera of the imaging module and the adjustable lens, which can greatly reduce the problem of overexposure of the imaging, facilitate accurate finding of the focus of the light spot, and reduce the damage to the camera. The mass spectrometer of the present invention has no optical reflection structure, is easy to install, has low cost, compact structure, and small size.

Description

Technical Field

[0001] The present invention relates to the technical field of mass spectrometry detection instruments, in particular to a mass spectrometer. Background Art

[0002] Matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOFMS) is a widely used biological mass spectrometer. It forms a co-crystal by mixing the sample to be analyzed with the matrix. When the laser irradiates the co-crystal, the matrix absorbs the energy of the laser and then transfers the energy to the sample, causing the sample to undergo a desorption and ionization process. The particles generated by the sample ionization are accelerated under the action of the electric field and eventually reach the time-of-flight mass spectrometer detector. Different substances arrive at the mass spectrometer detector at different times, so the molecular weight of the ions can be accurately calculated based on the arrival time of different ions.

[0003] The existing mass spectrometer usually includes a laser module, an ion source module, an illumination module and an imaging module. The sample mixed with the matrix to form a co-crystal is placed on the target material, and the target material is placed below the ion source module. The laser emitted by the laser module passes through the ion source module and irradiates the sample on the target material. The sample absorbs the energy of the laser to produce desorption and ionization. The ions generated by the sample ionization are accelerated by the ion source module to reach the flight time mass spectrometer detector. During sample analysis, since the distribution of the generated co-crystals on the surface of the target material is often uneven, the crystal state of some positions is better, and more crystalline materials are formed, while no crystalline materials are formed in some positions. Therefore, in the process of laser sample analysis, the operator needs to be able to see the ionization state of the sample at different target positions in real time, so as to select the most suitable analysis point for the experiment. Therefore, an imaging module is required to capture the sample image, and an illumination module is required to provide illumination. However, the current illumination module is arranged above the ion source module, and the illumination light emitted by the illumination module is irradiated onto the sample through an optical reflection mechanism. Since the target material where the sample is located is placed below the acceleration component, the illumination light emitted by the illumination module must pass through the acceleration component before it can be irradiated onto the sample. The acceleration assembly consists of two electrodes arranged one above the other, with a grid structure in the middle of the electrode. The illumination light passes through the electrode and irradiates the sample. The grid structure on the electrode is captured by the imaging module together with the sample. The image is shown in the figure below. Fig.10 As shown, the image captured by the imaging module will be interfered by the electrode sheet, resulting in poor imaging effect.

[0004] The prior art discloses an optical system of a mass spectrometer, which is characterized in that it includes a laser unit, an illumination unit, an imaging unit and an optical reflection mechanism; the laser unit, the illumination unit and the imaging unit are arranged outside the ion source cavity of the mass spectrometer, and the optical reflection mechanism is arranged inside the ion source cavity; the laser emitted by the laser unit is reflected by the optical reflection mechanism and then emitted to the sample surface, and the angle between the reflected laser light and the axis perpendicular to the sample target plate is greater than 0° and less than 10°; the illumination light emitted by the illumination unit is reflected by the optical reflection mechanism and then irradiated to the sample surface, and the angle between the illumination light reflected by the optical reflection mechanism and the axis perpendicular to the sample target plate is greater than 0° and less than 10°; the illumination light reflected by the sample is reflected by the optical reflection mechanism and then emitted into the imaging unit, and the imaging unit is used to receive the illumination light reflected by the sample for sample imaging. The illumination light emitted by the illumination unit of this patent is reflected by the optical reflection mechanism and then passes through the lead-out pole piece of the pole piece assembly before irradiating the large sample target plate. As a result, the pole piece grid will be captured by the imaging unit together with the sample, resulting in the pole piece grid structure on the captured image, which will cause occlusion and blurring of the sample, interfere with the imaging of the sample, and result in poor imaging effect. Summary of the invention

[0005] The purpose of the present invention is to provide a mass spectrometer with good imaging effect.

[0006] In order to achieve the above-mentioned purpose, the present invention provides a mass spectrometer, including an ion source module, an illumination module and an imaging module, the ion source module including an ion source cavity, an acceleration assembly and a target material, the acceleration assembly is arranged inside the ion source cavity, the target material is located below the ion source cavity, the illumination module and the imaging module are connected to the ion source cavity, the target material is used for placing a sample, the illumination module is used for emitting illumination light to irradiate the surface of the sample, the imaging module is used for receiving the illumination light reflected by the sample for sample imaging, and the acceleration assembly is not located on the light path of the illumination light emitted by the illumination module.

[0007] As a preferred solution, the accelerating assembly includes a first accelerating electrode sheet and a second accelerating electrode sheet arranged in parallel and spaced apart, the first accelerating electrode sheet is located above the second accelerating electrode sheet, and neither the first accelerating electrode sheet nor the second accelerating electrode sheet is located in the optical path of the illumination light emitted by the illumination module.

[0008] As a preferred solution, the emission point of the illumination light emitted by the illumination module is closer to the target material than the second accelerating electrode sheet.

[0009] As a preferred solution, the lighting module includes a mounting plate and a lighting component, one end of the mounting plate is connected to the ion source chamber, and the lighting component is connected to the mounting plate.

[0010] As a preferred embodiment, the lighting assembly includes a light source, a fixed sleeve and a movable sleeve, the fixed sleeve is rotatably connected to the mounting plate, the movable sleeve is detachably connected to the fixed sleeve, and the light source is located in a cylinder formed by the movable sleeve and the fixed sleeve.

[0011] As a preferred embodiment, the imaging module includes a camera, an adjustable lens and a plane window, wherein the plane window, the adjustable lens and the camera are arranged in sequence from the object side to the image side along the optical axis, the ion source cavity is provided with a connecting hole communicating with its interior, and the plane window is arranged in the connecting hole.

[0012] As a preferred solution, the imaging module further includes a filter, and the filter is arranged between the camera and the adjustable lens.

[0013] As a preferred embodiment, the ion source module also includes a focusing tube, which is vertically connected to the ion source cavity and one end of which extends into the interior of the ion source cavity. The acceleration assembly and the focusing tube are located on the same straight line, and the axis of the imaging module forms a certain angle with the focusing tube.

[0014] As a preferred solution, it further comprises a moving module, the target material is arranged on the moving module, and the moving module is used to drive the target material to move along two perpendicular directions.

[0015] As a preferred solution, the mobile module includes a first mobile platform, a second mobile platform and a carrying platform, the first mobile platform is perpendicular to the second mobile platform, the carrying platform, the first mobile platform and the second mobile platform are arranged in sequence from top to bottom, the first mobile platform can be movably connected to the second mobile platform along the length direction of the second mobile platform, and the carrying platform can be movably connected to the first mobile platform along the length direction of the first mobile platform.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The lighting module of the present invention provides illumination for an imaging module to photograph a sample on a target material. By not arranging an acceleration component located above the target material in the light path of the illumination light emitted by the lighting module, it is possible to prevent the acceleration component from blocking the sample and prevent the acceleration component from forming projections, reflections, etc. on the target material, which would cause blurred imaging of the sample. The imaging module only captures the image of the sample on the target material, which enables the final imaging to be clear, free of environmental noise, and have a good imaging effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a first-view structural diagram of an ion source module, an illumination module and an imaging module according to an embodiment of the present invention.

[0019] Figure 2 It is a second viewing angle structural schematic diagram of the ion source module, the illumination module and the imaging module of an embodiment of the present invention.

[0020] Figure 3 yes Figure 2 Section view along AA direction.

[0021] Figure 4 It is an exploded view of the ion source module, the illumination module and the imaging module of an embodiment of the present invention from a first viewing angle.

[0022] Figure 5 It is an exploded view of the ion source module, the illumination module and the imaging module of the embodiment of the present invention from a second viewing angle.

[0023] Figure 6 yes Figure 5 Cross-sectional view along BB direction.

[0024] Figure 7 It is a light path diagram of the ion source module, the illumination module and the imaging module of an embodiment of the present invention.

[0025] Figure 8 It is a schematic structural diagram of an ion source module, an illumination module, an imaging module and a moving module according to an embodiment of the present invention.

[0026] Fig. 9 It is a cross-sectional view of an ion source module, an illumination module, an imaging module and a moving module according to an embodiment of the present invention.

[0027] Fig.10 It is a schematic diagram of sample target imaging in the prior art.

[0028] Fig.11 Schematic diagram of sample target imaging according to an embodiment of the present invention.

[0029] In the figure, 100-ion source module; 110-ion source cavity; 111-connecting hole; 120-target material; 130-first accelerating electrode plate; 140-second accelerating electrode plate; 150-focusing tube; 200-illumination module; 210-mounting plate; 211-first mounting part; 212-second mounting part; 220-light source; 230-fixed sleeve; 240-movable sleeve; 300-imaging module; 310-camera; 320-adjustable lens; 330-plane window; 340-filter; 350-window sealing ring; 360-plane window pressure block; 370-adjusting lens fixing piece; 400-movable module; 410-first moving platform; 420-second moving platform; 430-carrying platform. DETAILED DESCRIPTION

[0030] The specific implementation of the present invention is further described in detail below in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0031] In the description of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0032] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0033] Embodiment 1

[0034] like Figures 1 to 9 As shown, a mass spectrometer of a preferred embodiment of the present invention includes an ion source module 100, an illumination module 200 and an imaging module 300. The ion source module 100 includes an ion source chamber 110, an acceleration assembly and a target material 120. The acceleration assembly is arranged inside the ion source chamber 110, and the target material 120 is located below the ion source chamber 110. The illumination module 200 and the imaging module 300 are connected to the ion source chamber 110. The target material 120 is used for placing samples. The illumination module 200 is used for emitting illumination light to irradiate the surface of the sample. The imaging module 300 is used for receiving illumination light reflected by the sample for sample imaging. The acceleration assembly is not located on the light path of the illumination light emitted by the illumination module 200. The lighting module 200 of the present embodiment provides illumination for the imaging module 300 to photograph the sample on the target material 120. By not arranging the acceleration component located above the target material 120 in the light path of the illumination light emitted by the lighting module 200, it is possible to prevent the acceleration component from blocking the sample and prevent the acceleration component from forming projections, reflections, etc. on the target material 120, which would cause blurred imaging of the sample. The imaging module 300 only captures the image of the sample on the target material 120, which can make the final image clear, free of environmental noise, and have a good imaging effect.

[0035] It should be noted that the “light path of the illumination light emitted by the illumination module 200 ” described in this embodiment refers to the light path between the illumination module 200 and the sample on the target 120 , and the acceleration component may be located on the light path between the sample on the target 120 and the imaging module 300 .

[0036] In this embodiment, the acceleration assembly includes a first accelerating electrode sheet 130 and a second accelerating electrode sheet 140 which are arranged in parallel and spaced apart. The first accelerating electrode sheet 130 is located above the second accelerating electrode sheet 140, and the first accelerating electrode sheet 130 and the second accelerating electrode sheet 140 are not located on the optical path of the illumination light emitted by the illumination module 200. The first accelerating electrode sheet 130 and the second accelerating electrode sheet 140 are used to form an accelerating electric field. The first accelerating electrode sheet 130 of this embodiment is used to load an exponential pulse voltage, and the second accelerating electrode sheet 140 is used to load a square pulse voltage, wherein the exponential pulse voltage and the square pulse voltage have the same frequency, and under the exponential pulse voltage and the square pulse voltage, the ions generated by the ionization of the sample are accelerated so that ions of the same mass number arrive at the detector at the same time.

[0037] The mass spectrometer of this embodiment further includes an optical reflection mechanism, and the illumination light emitted by the illumination module 200 is reflected by the optical reflection mechanism and irradiated onto the sample located on the target 120. The acceleration component is not located on the optical path between the illumination module 200 and the optical reflection mechanism, and the acceleration component is not located on the optical path of the illumination light reflected by the optical reflection mechanism. It should be noted that the illumination light reflected by the optical reflection mechanism has and only has the target 120 on its optical path.

[0038] Embodiment 2

[0039] The difference between this embodiment and the first embodiment is that, based on the first embodiment, this embodiment further illustrates the lighting module 200 .

[0040] In this embodiment, the exit point of the illumination light emitted by the illumination module 200 is closer to the target 120 than the second accelerating electrode sheet 140. That is, the exit point of the illumination light emitted by the illumination module 200 of this embodiment is lower than the second accelerating electrode sheet 140, which can ensure that the illumination light emitted by the illumination module 200 does not pass through the first accelerating electrode sheet 130 and the second accelerating electrode sheet 140. In addition, the illumination module 200 is close to the target 120, which can provide more sufficient illumination and improve the brightness of the imaging.

[0041] Furthermore, the illumination module 200 of the present embodiment emits illumination light directly onto the target 120, and the illumination light emitted by the illumination module 200 does not pass through an optical reflection mechanism. Therefore, there is no optical reflection mechanism between the illumination module 200 of the present embodiment and the target 120, which reduces the number of components of the mass spectrometer, makes installation easier, reduces costs, and makes the mass spectrometer compact, small in size, and has higher imaging clarity.

[0042] The lighting module 200 of this embodiment includes a mounting plate 210 and a light assembly, one end of the mounting plate 210 is connected to the ion source chamber 110, and the light assembly is connected to the mounting plate 210. Through the mounting plate 210, the light assembly can be installed in the ion source chamber 110, so that the exit point of the lighting light emitted by the lighting module 200 is lower than the second accelerating electrode sheet 140. The mounting plate 210 includes a first mounting portion 211 and a second mounting portion 212. The first mounting portion 211 is parallel to the inner wall of the ion source chamber 110 and is connected to the inner wall of the ion source chamber 110. One end of the second mounting portion 212 is connected to the first mounting portion 211. The second mounting portion 212 is tilted and tilted downward from the end connected to the first mounting portion 211 to the end away from the first mounting portion 211. The end of the second mounting portion 212 away from the first mounting portion 211 is closer to the second accelerating electrode sheet 140 than the end connected to the first mounting portion 211, which can shorten the distance between the lighting assembly and the target material 120, provide more sufficient lighting, clearer imaging, and facilitate installation.

[0043] Specifically, the lighting assembly includes a light source 220, a fixed sleeve 230 and a movable sleeve 249, the fixed sleeve 230 is rotatably connected to the mounting plate 210, the movable sleeve 240 is detachably connected to the fixed sleeve 230, and the light source 220 is located in a cylinder formed by the movable sleeve 240 and the fixed sleeve 230. The light source 220 is located in the cylinder formed by the movable sleeve 240 and the fixed sleeve 230, which can protect the light source 220 and facilitate the installation of the light source 220. The movable sleeve 240 is detachably connected to the fixed sleeve 230, so that the movable sleeve 240 is detachable and convenient for replacing the light source 220. In this embodiment, the movable sleeve 240 is threadedly connected to the fixed sleeve 230. The fixed sleeve 230 is rotatably connected to the mounting plate 210, and the optical path of the illumination light emitted by the light source 220 can be adjusted to ensure that the illumination light irradiates the surface of the sample located on the target 120.

[0044] Optionally, the light source 220 of this embodiment adopts an LED lamp, and the lighting assembly further includes a PWM control circuit, and the brightness of the light source 220 is adjusted by the PWM control circuit.

[0045] The other structures of this embodiment are the same as those of the first embodiment and will not be described again here.

[0046] Embodiment 3

[0047] The difference between this embodiment and the second embodiment is that, based on the second embodiment, this embodiment further illustrates the imaging module 300 .

[0048] In this embodiment, the imaging module 300 includes a camera 310, an adjustable lens 320 and a plane window 330. The plane window 330, the adjustable lens 320 and the camera 310 are arranged in sequence from the object side to the image side along the optical axis. The ion source chamber 110 is provided with a connecting hole 111 communicating with the interior thereof, and the plane window 330 is arranged in the connecting hole 111. The adjustable lens 320 can be moved along the optical axis. By rotating the adjustable lens 320, the clarity of the imaging can be adjusted to the clearest image quality. The adjustable lens 320 can adjust the focal length of the magnification.

[0049] Furthermore, the imaging module 300 of this embodiment further includes a filter 340, which is disposed between the camera 310 and the adjustable lens 320. The filter 340 can filter out most of the laser light with a wavelength of 400 nm, greatly reducing the problem of overexposure in imaging, making it easier to accurately find the focus of the light spot when debugging the optical path, and reducing the damage of ultraviolet light to the camera 310.

[0050] In the present embodiment, the imaging module 300 further includes a window seal ring 350, a plane window pressing block 360 and an adjusting lens fixing member 370. Two window seal rings 350 are provided. The plane window 330 is provided between the two window seal rings 350. The plane window 330 and the two window seal rings 350 are provided in the connecting hole 111. The plane window pressing block 360 is connected to the ion source chamber 110. The adjustable lens 320 is connected to the adjusting lens fixing member 370 and the plane window pressing block 360. The inner wall of the lower end of the adjustable lens 320 is provided with an internal thread, and the outer wall of the lower end is provided with an external thread. The outer wall of the plane window pressing block 360 is provided with an external thread. The inner wall of the adjusting lens fixing member 370 is provided with an internal thread. The internal thread of the adjustable lens 320 is connected to the external thread of the plane window pressing block 360. The external thread of the adjustable lens 320 is connected to the internal thread of the adjusting lens fixing member 370. By rotating the adjustable lens 320, the adjustable lens 320 moves relative to the plane window pressing block 360 to adjust the imaging clarity. In this embodiment, the plane window pressing block 360 is a quartz plane window, the camera 310 is an industrial camera, and the filter 340 is threadedly connected to the adjustable lens 320.

[0051] During installation, a window seal ring 350 is first placed in the connecting hole 111, and then the plane window 330 is placed, and then another window seal ring 350 is placed, and then the plane window pressing block 360 is connected to the ion source chamber 110 by bolts, and the plane window pressing block 360 is located outside the ion source chamber 110, and the plane window pressing block 360 restricts the window seal ring 350 and the plane window pressing block 360 on the ion source chamber 110. Then the internal thread of the adjusting lens fixing member 370 is screwed on the lower end external thread of the adjustable lens 320, and then the lower end internal thread of the adjustable lens 320 is screwed on the external thread of the plane window pressing block 360. Then the external thread of the filter 340 is screwed on the internal thread of the adjustable lens 320, and then the rotation angle of the camera 310 is adjusted and then installed on the filter 340. Finally, the internal thread of the adjusting lens fixing member 370 is screwed on the external thread of the plane window pressing block 360.

[0052] In addition, the ion source module 100 of the present embodiment further includes a focusing tube 150, which is vertically connected to the ion source cavity 110, and one end of the focusing tube 150 extends into the interior of the ion source cavity 110, the acceleration assembly and the focusing tube 150 are located on the same straight line, and the axis of the imaging module 300 forms a certain angle with the focusing tube 150. The mass spectrometer of the present embodiment further includes a laser module, which is used to emit laser light, which is injected into the ion source cavity 110 through the focusing tube 150, and irradiates the sample surface on the target material 120 through the ion source cavity 110. The axis of the imaging module 300 forms a certain angle with the focusing tube 150, which can prevent the optical path of the laser and the optical path of the illumination light reflected by the sample from interfering with each other, so that the illumination light reflected by the sample can be directly injected into the imaging module 300 without passing through the optical reflection mechanism, thereby reducing the components of the mass spectrometer, simplifying the structure, facilitating installation, reducing costs, and making the mass spectrometer compact and small in size, and also making the imaging clearer. The optical path of the illumination light emitted by the illumination module 200 of this embodiment and the optical path of the illumination light reflected by the sample are as follows: Figure 7 shown.

[0053] The other structures of this embodiment are the same as those of the second embodiment and will not be described again here.

[0054] Embodiment 4

[0055] The difference between this embodiment and the third embodiment is that, based on the third embodiment, the mass spectrometer of this embodiment further includes a moving module 400 .

[0056] In this embodiment, the mass spectrometer further includes a moving module 400, on which the target 120 is disposed, and the moving module 400 is used to drive the target 120 to move in two perpendicular directions. The moving module 400 can drive the target 120 to move, so that the illumination light emitted by the illumination module 200 is always focused on the sample target point on the target 120, providing sufficient light input for imaging the sample target point.

[0057] Specifically, the mobile module 400 of this embodiment includes a first mobile platform 410, a second mobile platform 420 and a carrier 430, the first mobile platform 410 is perpendicular to the second mobile platform 420, the carrier 430, the first mobile platform 410 and the second mobile platform 420 are arranged in sequence from top to bottom, the first mobile platform 410 can be movably connected to the second mobile platform 420 along the length direction of the second mobile platform 420, and the carrier 430 can be movably connected to the first mobile platform 410 along the length direction of the first mobile platform 410. The target material 120 is placed on the carrier 430, and the sample target point can be adjusted by moving the carrier 430 and the first mobile platform 410.

[0058] Optionally, the first mobile platform 410 of this embodiment is provided with a first motor and a first screw slider mechanism, the first motor is in transmission connection with the first screw slider mechanism, the second mobile platform 420 is provided with a second motor and a second screw slider mechanism, the second motor is in transmission connection with the second screw slider mechanism. The first mobile platform 410 is connected to the slider of the second screw slider mechanism, and the bearing platform 430 is connected to the slider of the first screw slider mechanism.

[0059] The other structures of this embodiment are the same as those of the third embodiment and will not be described again here.

[0060] In summary, an embodiment of the present invention provides a mass spectrometer, wherein the lighting module 200 provides illumination for the imaging module 300 to photograph the sample on the target material 120. By not arranging the acceleration component above the target material 120 in the light path of the illumination light emitted by the lighting module 200, it is possible to prevent the acceleration component from blocking the sample and prevent the acceleration component from forming projections, reflections, etc. on the target material 120, which may cause blurred imaging of the sample. The imaging module 300 only captures the image of the sample on the target material 120, so that the final imaging is clear, free of environmental noise, and has a good imaging effect. Moreover, the exit point of the illumination light emitted by the illumination module 200 is lower than the second accelerating electrode sheet 140 of the accelerating assembly of the ion source module 100, which can ensure that the illumination light emitted by the illumination module 200 does not pass through the first accelerating electrode sheet 130 and the second accelerating electrode sheet 140, so that the illumination module 200 is closer to the target material 120, so that the illumination provided by the illumination light is sufficient, and there is no optical reflection mechanism between the illumination module 200 and the target material 120, and between the target material 120 and the imaging module 300 of the embodiment of the present invention, which simplifies the structure of the mass spectrometer, makes the instrument easy to install, reduces costs, and makes the structure of the mass spectrometer compact and small in size. In addition, a filter 340 is provided between the camera 310 of the imaging module 300 and the adjustable lens 320. The filter 340 can filter out lasers of a specific wavelength, greatly reducing the problem of overexposure in imaging, and facilitating accurate finding of the focus of the light spot when debugging the optical path. Reduce the damage of ultraviolet light to the camera 310.

[0061] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and substitutions can be made without departing from the technical principles of the present invention. These improvements and substitutions should also be regarded as the scope of protection of the present invention.

Claims

1. A mass spectrometer, characterized in that The invention comprises an ion source module (100), an illumination module (200) and an imaging module (300), wherein the ion source module (100) comprises an ion source cavity (110), an acceleration component and a target material (120), wherein the acceleration component is arranged inside the ion source cavity (110), the target material (120) is located below the ion source cavity (110), the illumination module (200) and the imaging module (300) are connected to the ion source cavity (110), the target material (120) is used for placing a sample, the illumination module (200) is used for emitting illumination light to irradiate the surface of the sample, the imaging module (300) is used for receiving illumination light reflected by the sample for sample imaging, and the acceleration component is not located on the light path of the illumination light emitted by the illumination module (200); The imaging module (300) comprises a camera (310), an adjustable lens (320) and a plane window (330), wherein the plane window (330), the adjustable lens (320) and the camera (310) are arranged in sequence from the object side to the image side along the optical axis, the ion source chamber (110) is provided with a connection hole (111) communicating with the interior thereof, and the plane window (330) is arranged in the connection hole (111); The imaging module (300) further comprises a filter (340), wherein the filter (340) is arranged between the camera (310) and the adjustable lens (320).

2. The mass spectrometer according to claim 1, characterized in that The accelerating assembly comprises a first accelerating electrode sheet (130) and a second accelerating electrode sheet (140) which are arranged in parallel and spaced apart from each other, the first accelerating electrode sheet (130) being located above the second accelerating electrode sheet (140), and neither the first accelerating electrode sheet (130) nor the second accelerating electrode sheet (140) being located on the optical path of the illumination light emitted by the illumination module (200).

3. The mass spectrometer according to claim 2, characterized in that The emission point of the illumination light emitted by the illumination module (200) is closer to the target material (120) than the second accelerating electrode sheet (140).

4. The mass spectrometer according to claim 3, characterized in that The lighting module (200) comprises a mounting plate (210) and a light assembly, one end of the mounting plate (210) is connected to the ion source chamber (110), and the light assembly is connected to the mounting plate (210).

5. The mass spectrometer according to claim 4, characterized in that The lighting assembly comprises a light source (220), a fixed sleeve (230) and a movable sleeve (240); the fixed sleeve (230) is rotatably connected to the mounting plate (210); the movable sleeve (240) is detachably connected to the fixed sleeve (230); and the light source (220) is located in a cylinder formed by the connection between the movable sleeve (240) and the fixed sleeve (230).

6. The mass spectrometer according to claim 1, characterized in that The ion source module (100) further comprises a focusing tube (150), wherein the focusing tube (150) is vertically connected to the ion source chamber (110), and one end of the focusing tube (150) extends into the interior of the ion source chamber (110), the acceleration assembly and the focusing tube (150) are located on the same straight line, and the axis of the imaging module (300) forms a certain angle with the focusing tube (150).

7. The mass spectrometer according to claim 1, characterized in that It also includes a moving module (400), the target material (120) is arranged on the moving module (400), and the moving module (400) is used to drive the target material (120) to move along two perpendicular directions.

8. The mass spectrometer according to claim 7, characterized in that The mobile module (400) comprises a first mobile platform (410), a second mobile platform (420) and a carrying platform (430); the first mobile platform (410) is perpendicular to the second mobile platform (420); the carrying platform (430), the first mobile platform (410) and the second mobile platform (420) are arranged in sequence from top to bottom; the first mobile platform (410) can be movably connected to the second mobile platform (420) along the length direction of the second mobile platform (420); and the carrying platform (430) can be movably connected to the first mobile platform (410) along the length direction of the first mobile platform (410).

Images