Devices for EEG monitoring and treatment

Abstract

The present invention relates to a device for electroencephalogram (EEG) monitoring and treatment, comprising: a brain electrode for detecting EEG signals and / or receiving control signals; an interface device, one end of which is connected to the brain electrode and the other end of which is used to connect to an electroencephalograph for transmitting the EEG signals to the electroencephalograph; and an electrode fixing device for fixing the brain electrode when the brain electrode is implanted in the skull. The device for electroencephalogram (EEG) monitoring and treatment according to an embodiment of the present invention can transmit the EEG signals detected by the brain electrode to the electroencephalograph through the interface device, and fix the brain electrode through the electrode fixing device, so that a stable EEG signal can be obtained during the EEG monitoring process, and the implantation position of the brain electrode in the brain can be guaranteed not to change during the monitoring process.

Description

Technical Field

[0001] The present invention generally relates to the field of medical device technology. More specifically, the present invention relates to a device for electroencephalogram monitoring and treatment. Background Art

[0002] Stereotactic electroencephalography (SEEG) is an invasive epilepsy diagnosis and treatment technology. It does not require craniotomy. Through stereotactic technology, electrodes are implanted into the brain to study the brain discharge of epileptic patients, thereby locating the epileptogenic zone or epileptogenic network to guide the resection plan of epilepsy surgery. SEEG is not only used for the localization diagnosis of epileptic seizures, but also provides a new treatment method for epilepsy surgery, namely radiofrequency thermocoagulation, which is difficult to achieve with subdural electrodes. After SEEG monitoring records an epileptic seizure, the radiofrequency thermocoagulation generator is connected to the corresponding target electrode contacts, and thermocoagulation treatment can be performed at the bedside without anesthesia. However, since brain electrodes need to be implanted in the brain, how to fix the brain electrodes to obtain stable EEG signals and stably transmit the EEG signals to the electroencephalograph is a current research hotspot. Summary of the invention

[0003] In view of the above-mentioned technical problems, the technical solution of the present invention provides a device for electroencephalogram monitoring and treatment.

[0004] In the technical solution of the present invention, a device for electroencephalogram monitoring and treatment is provided, comprising: a brain electrode, which is used to detect electroencephalogram signals and / or implement thermal coagulation treatment; an interface device, one end of which is connected to the brain electrode, and the other end of which is used to connect to an electroencephalograph and / or a radio frequency thermal coagulation generator, so as to transmit the electroencephalogram signal to the electroencephalograph and / or receive a control signal sent from the radio frequency thermal coagulation generator; and an electrode fixing device, which is used to fix the brain electrode when the brain electrode is implanted in the skull.

[0005] In one embodiment of the present invention, the interface device includes: a first end portion, which has a first interface surface and a first protrusion on one side of the first interface surface; and a second end portion, which has a second interface surface adapted to the shape of the first interface surface and a second protrusion on one side of the second interface surface, so that when the second interface surface is connected to the first interface surface, the first protrusion and the second protrusion are respectively located on both sides of the connection.

[0006] In another embodiment of the present invention, the other side of the first interface surface has a first end face opposite to the protruding direction of the first protrusion, and the first end face is adapted to the inner side face of the second protrusion; and the other side of the second interface surface has a second end face opposite to the protruding direction of the second protrusion, and the second end face is adapted to the inner side face of the first protrusion.

[0007] In one embodiment of the present invention, the first interface surface is rectangular, and the first convex portion is located on one side of a short side of the first interface surface; and the second interface surface is rectangular, and the second convex portion is located on one side of a short side of the second interface surface.

[0008] In another embodiment of the present invention, the first end also has a first connection port, which is located on the outer side of the first protrusion relative to the first interface surface, for connecting to an electroencephalograph; and the second end also has a second connection port, which is located on the outer side of the second protrusion relative to the second interface surface, for connecting to the brain electrode.

[0009] In one embodiment of the present invention, the first interface surface has a first plugging area, in which plug pins are arranged; and the second interface surface has a second plugging area, in which slots corresponding to the plug pins are arranged for plugging with the plug pins.

[0010] In another embodiment of the present invention, the first plugging area is recessed in the first interface surface; and the second plugging area is protruded on the second interface surface, and the protruding height of the second plugging area is equal to the recessed depth of the first plugging area.

[0011] In another embodiment of the present invention, the interface device also includes: at least one guide groove, which is arranged at the edge of one of the first plug-in area and the second plug-in area; and at least one guide block, which corresponds one-to-one to the at least one guide groove and is arranged at the edge of the other of the first plug-in area and the second plug-in area.

[0012] In one embodiment of the present invention, first anti-slip convex points are arranged on the outer surface of the first end portion; and / or second anti-slip convex points are arranged on the outer surface of the second end portion.

[0013] In another embodiment of the present invention, the electrode fixing device includes: a guide bolt, which is used to be fixed on the skull and has a first through hole; a nut, which is used to be connected to the guide bolt and has a second through hole; and a sealing plug, which is located between the guide bolt and the nut, or is located at the top of the nut and has a third through hole; wherein the first through hole, the second through hole and the third through hole are used for the brain electrode to pass through so as to fix the brain electrode.

[0014] In yet another embodiment of the present invention, a limiting portion is provided on the guide bolt, and the limiting portion is close to an end of the guide bolt for inserting into the skull.

[0015] In one embodiment of the present invention, the guide bolt has a clamping portion, which is located between one end of the guide bolt used for connecting with the nut and the limiting portion.

[0016] In another embodiment of the present invention, the guide bolt has a first groove at the first through hole at one end thereof for connecting with the nut; and the sealing plug is located between the guide bolt and the nut, and the sealing plug is inserted into the first groove toward one end of the guide bolt.

[0017] In another embodiment of the present invention, the first groove is an internal hexagonal structure; and one end of the sealing plug for inserting into the first groove has an external hexagonal structure adapted to the first groove, or the sealing plug as a whole has the external hexagonal structure.

[0018] In one embodiment of the present invention, a second groove is formed at the third through hole at one end of the sealing plug facing the nut.

[0019] In another embodiment of the present invention, the electrode fixing device also includes: a fastener, which is located between the guide bolt and the nut, and one end of which is integrally formed with the guide bolt or detachably connected, and the other end of which includes a plurality of baffles for surrounding the sealing plug; and the inner side of the nut has an inclined surface that is narrow at the top and wide at the bottom, so as to form radial extrusion on the plurality of baffles when the nut and the guide bolt are connected.

[0020] In one embodiment of the present invention, one end of the guide bolt used for connecting with the fastener has an internal hexagonal structure; one end of the fastener used for connecting with the guide bolt has an external hexagonal structure adapted to the internal hexagonal structure so as to be detachably connected to the guide bolt.

[0021] In another embodiment of the present invention, the electrode fixing device further comprises: a mold cavity, which is located at the top of the nut and has an inner cavity for placing the sealing plug, so as to radially squeeze the sealing plug when the inner cavity space is compressed.

[0022] In another embodiment of the present invention, the mold cavity includes a fastening baffle and a movable baffle, the fastening baffle has a threaded hole, and the movable baffle has a fourth through hole; and the electrode fixing device also includes: a fastening screw, which is used to compress the inner cavity space of the mold cavity when passing through the fourth through hole to be threadedly connected with the threaded hole.

[0023] In one embodiment of the present invention, the cavity and the nut are connected via a connecting portion, and a first connecting surface between the connecting portion and the nut is smaller than a cross-section of the nut; and / or a second connecting surface between the connecting portion and the cavity is smaller than a cross-section of the cavity.

[0024] Through the above description of the technical scheme of the present invention and its multiple embodiments, those skilled in the art can understand that the device for EEG monitoring and treatment of the present invention can transmit the EEG signals detected by the brain electrodes to the electroencephalograph through the interface device and / or receive the control signal sent from the radio frequency thermal coagulation generator to control the heating of the corresponding contacts of the brain electrodes and then implement thermal coagulation treatment, and fix the brain electrodes through the electrode fixing device to obtain stable EEG signals and / or receive stable control signals during the EEG monitoring and treatment process, and ensure that the implantation position of the brain electrodes in the brain does not change during the monitoring and treatment process.

[0025] In some embodiments, the first end including the first protrusion and the second end including the second protrusion can be provided so that the connection between the first end and the second end is tighter, which is conducive to ensuring the stability of brain signal transmission. In other embodiments, the through-holes of the nut, the guide bolt and the sealing plug can be provided so that the brain electrode can pass through them, and the guide bolt, the nut and the sealing plug can fix the brain electrode passing through the through-hole. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] By reading the following detailed description with reference to the accompanying drawings, the above and other objects, features and advantages of the exemplary embodiments of the present invention will become readily understood. In the accompanying drawings, several embodiments of the present invention are shown in an exemplary and non-limiting manner, and the same or corresponding reference numerals represent the same or corresponding parts, wherein:

[0027] Figure 1 is a schematic diagram showing an apparatus for electroencephalogram monitoring and treatment according to an embodiment of the present invention;

[0028] Figure 2a is a schematic diagram showing an interface device according to an embodiment of the present invention;

[0029] Figure 2b is a schematic diagram showing an interface device according to another embodiment of the present invention;

[0030] Figure 3 is a schematic diagram showing an interface device including a first connection port and a second connection port according to an embodiment of the present invention;

[0031] Figure 4 is a schematic diagram showing an interface device including a plug-in area according to an embodiment of the present invention;

[0032] Figure 5 is a schematic diagram showing a first end portion including a first plugging area according to an embodiment of the present invention;

[0033] Figure 6a is a schematic diagram showing an electrode fixing device according to an embodiment of the present invention;

[0034] Figure 6b is a schematic diagram showing a brain electrode being fixed on an electrode fixing device according to an embodiment of the present invention;

[0035] Figure 6c is a cross-sectional schematic diagram showing an electrode fixing device including a first groove according to an embodiment of the present invention;

[0036] Figure 7a is a schematic cross-sectional view showing a guide bolt in which the first groove is a hexagonal structure according to an embodiment of the present invention;

[0037] Figure 7b is a perspective schematic diagram showing a guide bolt in which the first groove is a hexagonal structure according to an embodiment of the present invention;

[0038] Figure 7c is a schematic diagram showing an electrode fixing device including an outer hexagonal sealing plug according to an embodiment of the present invention;

[0039] Figure 8 is a schematic diagram showing an electrode fixing device including a deformable sealing plug according to an embodiment of the present invention;

[0040] Fig. 9 is a schematic diagram showing an electrode fixing device including a second groove according to an embodiment of the present invention;

[0041] Fig.10 is a schematic diagram showing an electrode fixing device including a fastener according to an embodiment of the present invention;

[0042] Fig.11is a schematic diagram showing a state of an electrode fixing device in which multiple baffles are in a relaxed state according to an embodiment of the present invention;

[0043] Fig.12 is a schematic diagram showing a state of an electrode fixing device in which a plurality of baffles squeeze a sealing plug according to an embodiment of the present invention;

[0044] Fig.13 is a schematic diagram showing an electrode fixing device including a cavity according to an embodiment of the present invention;

[0045] Fig.14 is a top view showing a cavity according to an embodiment of the present invention;

[0046] Fig.15 is a cross-sectional view showing a cavity when a fastening screw passes through a through hole to be threadedly connected with a threaded hole according to an embodiment of the present invention; and

[0047] Fig.16 is a schematic diagram showing a connection portion according to an embodiment of the present invention. DETAILED DESCRIPTION

[0048] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0049] It should be understood that the terms "first", "second", "third" and "fourth" etc. in the claims, specifications and drawings of the present invention are used to distinguish different objects rather than to describe a specific order. The terms "include" and "comprise" used in the specification and claims of the present invention indicate the presence of the described features, wholes, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, wholes, steps, operations, elements, components and / or their collections.

[0050] It should also be understood that the terms used in this specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. As used in the specification of the present invention and the claims, the singular forms of "a", "an" and "the" are intended to include the plural forms unless the context clearly indicates otherwise. It should also be further understood that the term "and / or" used in the specification of the present invention and the claims refers to any combination of one or more of the associated listed items and all possible combinations, and includes these combinations.

[0051] As used in this specification and claims, the term "if" may be interpreted as "when" or "upon" or "in response to determining" or "in response to detecting," depending on the context. Similarly, the phrase "if it is determined" or "if [described condition or event] is detected" may be interpreted as meaning "upon determination" or "in response to determining" or "upon detection of [described condition or event]" or "in response to detecting [described condition or event]," depending on the context.

[0052] The specific embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0053] Figure 1 Schematic diagram of an apparatus for EEG monitoring and treatment according to an embodiment of the present invention. Figure 1 As shown in , the device 100 may include: a brain electrode 110, which is used to detect EEG signals and / or implement thermal coagulation treatment; an interface device 130, one end of which is connected to the brain electrode 110, and the other end of which is used to connect to an electroencephalograph for transmitting the EEG signals to the electroencephalograph, and the other end of which can also be used to connect to a radio frequency thermal coagulation generator for receiving a control signal sent from the radio frequency thermal coagulation generator to control the heating of the corresponding contacts of the brain electrode and then implement thermal coagulation treatment; and an electrode fixing device 120, which is used to fix the brain electrode 110 when the brain electrode 110 is implanted in the skull.

[0054] The brain electrode 110 described above can be an electroencephalogram sensor that can be implanted in the brain. In some embodiments, the electrode fixing device 120 can be used to be fixed on the skull, and it can have a hollow structure so that the brain electrode 110 can pass through it and be implanted in the brain. In other embodiments, the other end of the interface device 130 can be used to directly or indirectly connect to an electroencephalograph (e.g., a stereotactic electroencephalograph) and / or a radiofrequency coagulation generator. For example, the other end of the interface device 130 can be connected to the electroencephalograph and / or the radiofrequency coagulation generator by connecting multiple ports 140, so that the electroencephalogram signal recorded by the brain electrode 110 can be transmitted to the electroencephalograph via the interface device 130, and / or the control signal sent by the radiofrequency coagulation generator is transmitted to the brain electrode 110 via the interface device 130.

[0055] The inventors have found that if the interface device 130 uses a direct plug connection method (or pinhole connection method) such as a DIN connector (or pin-plug), when the interface device 130 is subjected to external force, the interface and the terminal may fall off, thereby causing the interruption of the signal connection, thereby affecting the safety and stability of the operation. Based on this, the inventors have provided a new and feasible solution to ensure the stability and reliability of the interface device 130. Figure 2a and Figure 2bAn exemplary description is given.

[0056] Figure 2a Schematic diagram of an interface device according to an embodiment of the present invention. Figure 2a As shown in, in one embodiment of the present invention, the interface device 130 may include: a first end 210, which may have a first interface surface 211, and may have a first protrusion 212 on one side of the first interface surface 211; and a second end 220, which may have a second interface surface 221 adapted to the shape of the first interface surface 211, and may have a second protrusion 222 on one side of the second interface surface 221, so that when the second interface surface 221 is connected to the first interface surface 211, the first protrusion 212 and the second protrusion 222 are respectively located on both sides of the connection.

[0057] The shape adaptation of the first interface surface 211 and the second interface surface 221 may include the shapes and sizes of the two being the same or similar, so that the two can be matched and connected. In some embodiments, a pin may be provided on one of the first interface surface 211 and the second interface surface 221, and a socket corresponding to the position and shape of the pin may be provided on the other of the two, so as to achieve the plug-in connection between the first interface surface 211 and the second interface surface 221. In other embodiments, the first interface surface 211 and the second interface surface 221 may also be connected by means such as magnetic attraction, as long as the signal transmission between the two can be achieved. Signal transmission at both ends of the interface device 130 can be achieved through the connection between the first interface surface 211 and the second interface surface 221.

[0058] In other embodiments, the shapes of the first interface surface 211 and the second interface surface 221 may not be limited to the rectangle shown in the figure, but may also be regular or irregular shapes such as square, rhombus, trapezoid, etc. Taking the rectangle shown in the figure as an example, the first convex portion 212 may be located on one side of the short side of the first interface surface 211 (such as Figure 2a ), or may be located on one side of the long side of the first interface surface 211 (not shown in the figure); the second convex portion 222 may be located on one side of the long side of the second interface surface 221 (as shown in the figure); Figure 2a ), or may be located on the short side of the second interface surface 221 ( Figure 2a When the second interface surface 221 is connected to the first interface surface 211, the first convex portion 212 and the second convex portion 222 may be located at two adjacent sides of the connection, or may be located at two opposite sides of the connection.

[0059] Figure 2b is a schematic diagram showing an interface device according to another embodiment of the present invention. Figure 2b The interface device shown is Figure 2a The interface devices shown differ in that Figure 2bThe second convex portion 222 is located on one side of the short side of the second interface surface 221. Further, in another embodiment of the present invention, the other side of the first interface surface 211 has a first end surface 213 opposite to the protruding direction of the first convex portion 212, and the first end surface 213 can be adapted to the inner side surface 224 of the second convex portion 222; and the other side of the second interface surface 221 has a second end surface 223 opposite to the protruding direction of the second convex portion 222, and the second end surface 223 can be adapted to the inner side surface 214 of the first convex portion 212.

[0060] In some embodiments, the other side of the first interface surface 211 may be the opposite side of the first interface surface 211 where the first convex portion 212 is located; the other side of the second interface surface 221 may be the opposite side of the second interface surface 221 where the second convex portion 222 is located. The inner side surface 224 of the second convex portion 222 is the side of the second convex portion 222 facing the second interface surface 221. The inner side surface 214 of the first convex portion 212 is the side of the first convex portion 212 facing the first interface surface 211. In some embodiments, the first end surface 213 adapted to the inner side surface 224 of the second convex portion 222 may include: the first end surface 213 and the inner side surface 224 of the second convex portion 222 have the same or similar shape and size. In other embodiments, the second end surface 223 adapted to the inner side surface 214 of the first convex portion 212 may include: the second end surface 223 and the inner side surface 214 of the first convex portion 212 have the same or similar shape and size.

[0061] Combination of the above Figure 2a and Figure 2b The interface device according to the embodiment of the present invention is described exemplarily. It can be understood that, according to the interface device of the embodiment of the present invention, a side connection structure can be formed between the first end and the second end, so that the connection between the two is tighter, and by providing the first convex portion and the second convex portion, more force can be borne at the first convex portion and the second convex portion to reduce the force on the first interface surface and the second interface surface, so that the first end and the second end are not easy to fall off when subjected to external force. In particular, compared with the interface device without the first convex portion and the second convex portion, or only one of the first convex portion and the second convex portion is provided, the simultaneous provision of the first convex portion and the second convex portion can effectively protect the connection structure between the first interface surface and the second interface surface, for example, when connected in the form of a pin and a socket, it can effectively prevent the pin from being bent by external force.

[0062] It can also be understood that by setting the first end face on the other side of the first interface surface and the second end face on the other side of the second interface surface, when the first interface surface 211 is connected to the second interface surface 221, the interface device 130 composed of the first end and the second end has a regular outer surface (for example, the outer surface is a rectangular structure, or a cube structure, etc.), so that the overall force of the interface device is more uniform and the connection is more stable.

[0063] Further, according to Figure 2b The structural setting of the interface device 130 in the embodiment of the present invention is that when the first interface surface and the second interface surface are both set to a rectangle, that is, the first end portion and the second end portion are both set to an L-shaped structure, and the first convex portion and the second convex portion are respectively located on opposite sides of the connection between the first interface surface and the second interface surface, the interface device can have an anti-foolproof effect, especially it can make the first interface surface and the second interface surface always maintain the same contact direction, and there will be no situation where the user flips one of the first interface surface and the second interface surface and then tries to connect it to the other one, thereby fundamentally avoiding the situation of reverse insertion, which is beneficial to improving the speed, safety and convenience of user operation.

[0064] For example, taking the connection between the first interface surface and the second interface surface through the pin and socket as an example, the multiple pins may not be arranged symmetrically. At this time, if there is no rectangular first interface surface and second interface surface, or the first convex portion and / or the second convex portion are missing, since there is no unique direction correspondence between the first interface surface and the second interface surface, the connection attempt may be flipped, resulting in the pin being unable to be inserted into the corresponding slot, so that the user needs to adjust the direction of the interface surface to try again. Therefore, according to the structural setting of the interface device shown in Figure 2, this problem can be perfectly solved.

[0065] Figure 3 2 is a schematic diagram showing an interface device including a first connection port and a second connection port according to an embodiment of the present invention. Figure 3 As shown in, in another embodiment of the present invention, the first end 210 may also have a first connection port 310, which may be located on the outer side surface 311 of the first protrusion 212 relative to the first interface surface, for connecting to an electroencephalograph; and the second end 220 also has a second connection port 320, which is located on the outer side surface 321 of the second protrusion 222 relative to the second interface surface, for connecting to the brain electrode 110.

[0066] In some embodiments, the outer side surface 311 of the first protrusion 212 may be aligned with the inner side surface (eg, Figure 2bIn other embodiments, the outer side surface 321 of the second convex portion 222 may be opposite to the inner side surface 214 of the second convex portion 222 (for example, the inner side surface 214 of the first convex portion 212 is the side of the first convex portion 212 facing the first interface surface, and the outer side surface 311 of the first convex portion 212 is the side of the first convex portion 212 facing away from the first interface surface. Figure 2b The inner side surface 224 shown in FIG. 2 is relatively speaking, that is, the inner side surface of the second protrusion 222 is the side of the second protrusion 222 facing the second interface surface, and the outer side surface 321 of the second protrusion 222 is the side of the second protrusion 222 facing away from the second interface surface.

[0067] like Figure 3 As shown in , when the first convex portion 212 and the second convex portion 222 are located on opposite sides of the connection between the first interface surface and the second interface surface, the first connection port 310 and the second connection port 320 can face opposite sides (i.e., 180°). In other embodiments, when the first convex portion 212 and the second convex portion 222 are located on adjacent sides of the connection between the first interface surface and the second interface surface (e.g. Figure 2a When the interface device shown in FIG. 1 is used, the first connection port 310 and the second connection port 320 can face directions perpendicular to each other (ie, at 90°).

[0068] It should be noted that due to the setting of the first protrusion 212 and the second protrusion 222, when the first connection port 310 and the second connection port 320 are respectively set on the outer side surfaces of the first protrusion 212 and the second protrusion 222, the first protrusion 212 and the second protrusion 222 can withstand the external force that may be applied, which is beneficial to improving the bearing capacity of the interface device and effectively avoiding sliding between the first interface surface and the second interface surface, thereby helping to improve the connection stability between the first interface surface and the second interface surface.

[0069] like Figure 3 As further shown in FIG. 1 , in some embodiments, a first anti-skid convex point 330 may be provided on the outer surface of the first end 210; and / or a second anti-skid convex point 340 may be provided on the outer surface of the second end 220. The provision of the first anti-skid convex point 330 and / or the second anti-skid convex point 340 facilitates the plugging and unplugging operation between the first end 210 and the second end 220. In some embodiments, the first anti-skid convex point 330 may be provided on one or more outer surfaces of the first end 210; and / or the second anti-skid convex point 340 may be provided on one or more outer surfaces of the second end 220.

[0070] The outer surface of the first end 210 may include the surface of the first end 210 exposed to the outside in the interface device formed after the first end 210 and the second end 220 are connected, such as the surface where the first anti-slip convex point 330 is located in the figure, and the back side of the first end 210 not shown in the figure. The outer surface of the second end 220 may include the surface of the second end 220 exposed to the outside in the interface device formed after the first end 210 and the second end 220 are connected, such as the surface where the second anti-slip convex point 340 is located in the figure, and the back side of the second end 220 not shown in the figure.

[0071] Combination of the above Figure 3 The interface device including the first connection port and the second connection port is described by way of example. It is to be understood that the above description is exemplary and not restrictive. For example, the first anti-slip protrusion 330 may not be limited to the position shown in the figure, but may also be provided on the outer surface of the first protrusion 212, for example; and / or the second anti-slip protrusion 340 may not be limited to the position shown in the figure, but may also be provided on the outer surface of the second protrusion 222, for example. For another example, in one embodiment of the present invention, the first interface surface and the second interface surface may be connected by plugging to achieve signal connection. Figure 4 and Figure 5 Give a description.

[0072] Figure 4 is a schematic diagram showing an interface device including a plug-in area according to an embodiment of the present invention; Figure 5 is a schematic diagram showing a first end portion including a first plugging area according to an embodiment of the present invention, wherein: Figure 5 Can be Figure 4 A schematic three-dimensional view of the first end portion of the interface device as viewed from the direction of the first interface surface.

[0073] like Figure 4 and Figure 5 As shown in , the first interface surface 211 of the first end 210 may have a first plugging area 510, and the first plugging area 510 may be provided with a pin 511; the second interface surface 221 of the second end 220 may have a second plugging area 410, and the second plugging area 410 may be provided with a slot 411 corresponding to the pin 511 one by one, for plugging with the pin 511. In some embodiments, the shapes and sizes of the first plugging area 510 and the second plugging area 410 may be adapted. In other embodiments, the number of pins 511 in the first plugging area 510 may be set to one or more. The slot 411 corresponding to the pin 511 one by one may include the number, position, shape, depth, etc. of the slot 411 corresponding to the pin 511. Further, the shapes of the first plugging area 510 and the second plugging area 410 may not be limited to the rectangle shown in the figure, and may be set to other shapes as needed.

[0074] In some embodiments, the pin 511 may be configured to protrude from the first interface surface 211, and the slot 411 may be configured to be recessed in the second interface surface 221. In other embodiments, the first plugging area 510 may be recessed in the first interface surface 211; and the second plugging area 410 may be protruded from the second interface surface 221, and the protruding height of the second plugging area 410 may be equal to the recessed depth of the first plugging area 510. According to such a configuration, the plugging between the pin 511 and the slot 411 may be more firmly connected, and it is also beneficial for the first interface surface 211 and the second interface surface 221 to be in close contact, so as to ensure the safety and stability of the internal line connection.

[0075] In another embodiment of the present invention, the interface device may further include: at least one guide groove 520, which may be disposed at an edge of one of the first plug-in area 510 and the second plug-in area 410; and at least one guide block, which corresponds to the at least one guide groove 520 and may be disposed at an edge of the other of the first plug-in area 510 and the second plug-in area 410. Figure 5 As further shown in the figure, at least one guide groove can be set at the edge of the first plug-in area 510, and guide blocks (not shown in the figure) corresponding to the guide grooves can be set at the corresponding edges of the second plug-in area 410, so that each guide block can be inserted into a corresponding guide groove.

[0076] In some embodiments, the guide groove 520 can be set to a square, circular, trapezoidal or other shape, and the guide block can be correspondingly set to the same shape as the guide groove 520. In other embodiments, when multiple guide grooves 520 are provided, they can be evenly spaced and distributed at, for example, the edge of the first plugging area 510, or can be symmetrically arranged at, for example, the edge of the first plugging area 510. The provision of the guide grooves and the corresponding guide blocks is conducive to the positioning and alignment of the first plugging area and the second plugging area, thereby facilitating the insertion of the pin into the slot.

[0077] Understandably, Figure 5 The figure is exemplary and not restrictive. For example, the guide groove 520 may not be limited to the edge of the first plugging area 510, and may be provided at the edge of the second plugging area 410 as required. For another example, the pin may not be limited to being provided in the first plugging area 510, and the slot may not be limited to being provided in the second plugging area 410, and the pin may be provided in the second plugging area 410 as required, and the slot may be provided in the first plugging area 510. Furthermore, a PCB board may be provided in the second end 220, so that all the contacts of the brain electrode may be collected on the PCB board, so as to be connected to the cable through the PCB board and via the first end 210.

[0078] The above combined with Figure 2- Figure 5 The interface device according to the embodiment of the present invention is described in detail. Figure 6a-6c An electrode fixing device according to an embodiment of the present invention is described. Figure 6a is a schematic diagram showing an electrode fixing device according to an embodiment of the present invention. Figure 6b is a schematic diagram showing that a brain electrode is fixed to an electrode fixing device according to an embodiment of the present invention.

[0079] like Figure 6a and Figure 6b As shown in , the electrode fixing device 120 may include: a guide bolt 610, which can be used to be fixed on the skull and has a first through hole; a nut 620, which can be used to connect with the guide bolt 610 and has a second through hole; and a sealing plug 630, which can be located between the guide bolt 610 and the nut 620, or located on the top of the nut 620, and has a third through hole; wherein the first through hole, the second through hole and the third through hole are used for the brain electrode 110 to pass therethrough (for example Figure 6b ), in order to fix the brain electrode 110.

[0080] The guide bolt 610 has a guiding effect on the brain electrode passing through the first through hole. In some embodiments, the end of the guide bolt 610 used for fixing with the skull may have a threaded structure so that the guide bolt 610 can be screwed into the skull to achieve the purpose of fixing the brain electrode on the skull. In some embodiments, the guide bolt 610 and the nut 620 can be connected by threads, or can be set to a connection method such as a snap connection or a plug connection. In other embodiments, the sealing plug 630 can have toughness and can be made of materials such as rubber and silicone. In some embodiments, the sealing plug 630 can be directly or indirectly fixed to the top of the nut 620, and the top of the nut 620 is the end of the nut 620 that is not connected to the guide bolt 610. In other embodiments, the sealing plug 630 can be squeezed by the sealing plug 630 so that the sealing plug 630 can clamp the brain electrode, thereby achieving the fixation of the brain electrode. In another embodiment of the present invention, a limiting portion 640 can be provided on the guide bolt 610, and the limiting portion 640 can be close to one end of the guide bolt 610 for inserting into the skull. In some embodiments, the limiting portion 640 may be, for example, a ring structure as shown in the figure, and is fixed to the guide bolt 610. The setting of the limiting portion 640 can prevent the guide bolt 610 from excessively rotating when installed on the skull, that is, it can limit the depth and position of the guide bolt 610 entering the skull, which is conducive to the fixation of the guide bolt 610.

[0081] As further shown in the figure, in one embodiment of the present invention, the guide bolt 610 may also have a clamping portion 650, which may be located between one end of the guide bolt 610 for connecting with the nut 620 and the limiting portion 640. In some embodiments, the clamping portion 650 may be recessed in the surface of the guide bolt 610. In other embodiments, the clamping portion 650 may be set as a plane to facilitate clamping. In some other embodiments, the clamping portion 650 may include two, and are symmetrically arranged on both sides of the radial direction of the guide bolt 610. In some embodiments, the clamping portion 650 may include four, and are symmetrically arranged on the radial periphery of the guide bolt 610. In other embodiments, the clamping portion 650 may also have a rough surface. By providing the clamping portion 650, it is convenient to clamp it with a clamping tool, so that the installation and control of the guide bolt 610 can be facilitated.

[0082] like Figure 6b As shown in the figure, the brain electrode 110 can pass through the second through hole of the nut 620, the third through hole of the sealing plug (not shown in the figure) and the first through hole of the guide bolt 610 in sequence, wherein the sealing plug can be arranged between the nut 620 and the guide bolt 610, so as to form an extrusion on the brain electrode 110 when the nut 620 is connected with the guide bolt 610, thereby achieving the purpose of fixing the brain electrode 110. One end of the guide bolt 610 is used to connect with the nut 620, and the other end of the guide bolt 610 can be used to connect with the skull, so that the brain electrode passing through the electrode fixing device can be fixed on the skull.

[0083] Combination of the above Figure 6a and Figure 6b An exemplary description has been given of the electrode fixing device according to the embodiment of the present invention. It should be understood that conventional skull screws are generally made of titanium alloy or other polymer materials with good biocompatibility, and the skull screws are usually of a self-tapping structure, that is, the screw shank is provided with a self-tapping groove, and the other end of the skull screw is generally a screw head with a cross groove, which is used to cooperate with the screwing operation of a special bolt driver to fix the skull screw on the skull or to repair the skull. However, conventional skull screws cannot be used to fix brain electrodes. Therefore, compared to the conventional skull screw structure, the electrode fixing device of the embodiment of the present invention can achieve the fixation of brain electrodes at the same time when it is fixed on the skull through the through-hole setting and the interaction between the guide bolt, the nut and the sealing plug.

[0084] Figure 6c FIG. 2 is a schematic cross-sectional view of an electrode fixing device including a first groove according to an embodiment of the present invention. Figure 6cAs shown in, the electrode fixing device may include a guide bolt 610, a nut 620 and a sealing plug 630, wherein the guide bolt 610 has a first through hole 611, the nut 620 has a second through hole 621, the sealing plug 630 has a third through hole 631, and the first through hole 611 at one end of the guide bolt 610 for connecting with the nut 620 may have a first groove 612, that is, the first groove 612 is located at one end of the guide bolt 610 for connecting with the nut 620, and the first groove 612 may be communicated with the first through hole 611.

[0085] Furthermore, the sealing plug 630 can be located between the guide bolt 610 and the nut 620, and one end of the sealing plug 630 facing the guide bolt 610 can be inserted into the first groove 612, so that the sealing plug 630 can be squeezed when the guide bolt 610 is connected to the nut 620, and the brain electrode passing therethrough can be clamped by the deformation of the sealing plug 630, and because the first groove 612 has a supporting effect on the bottom of the sealing plug 630, the sealing plug 630 can only be deformed but not move downward.

[0086] like Figure 6c As further shown in FIG. 1 , in another embodiment, the other end 613 of the guide bolt 610 may have a self-tapping thread. In some embodiments, the self-tapping thread may have a certain angle variation so that the guide bolt 610 can be self-tapping and screwed into the skull. In other embodiments, the screwing distance can be determined by the number of turns of the self-tapping thread. In still other embodiments, the pitch of the self-tapping thread can be set according to factors such as torque and target wall thickness. In some embodiments, the guide bolt 610 can be made of titanium alloy material or resin material.

[0087] Combination of the above Figure 6c The structure of the electrode fixing device including the first groove according to the present invention is described exemplarily. It can be understood that the shape of the first groove 612 can include a cylindrical, conical, square, hexagonal structure, etc., and the outer surface structure of the sealing plug 630 can be adapted to the structure of the first groove 612. Figure 7a-7c An exemplary description is given.

[0088] Figure 7a 1 is a schematic cross-sectional view showing a guide bolt in which the first groove is a hexagonal structure according to an embodiment of the present invention. Figure 7b 2 is a perspective schematic diagram showing a guide bolt in which the first groove is a hexagonal structure according to an embodiment of the present invention. Figure 7a and Figure 7b As shown in , in another embodiment of the present invention, the first groove 612 on the guide bolt 610 may be a hexagonal structure, the first through hole 611 may be cylindrical, and the first groove 612 may be connected to the first through hole 611.

[0089] Figure 7c Schematic diagram of an electrode fixing device including an outer hexagonal sealing plug according to an embodiment of the present invention. Figure 7c As shown in FIG. 1 , the electrode fixing device includes a guide bolt 610, a nut 620 and a sealing plug 630. Figure 7a and Figure 7b The outer surface of the sealing plug 630 may be an outer hexagonal structure that matches the shape of the first groove 612 in the sealing plug 630. In other embodiments, the sealing plug 630 may not be limited to being an outer hexagonal structure as a whole, and the end of the sealing plug 630 that is used to be inserted into the first groove may have an outer hexagonal structure that matches the first groove, and the portion of the sealing plug 630 that is exposed from the first groove may be set to a cylindrical, conical, or other structure.

[0090] According to such a configuration, after the sealing plug 630 is inserted into the first groove, no radial movement occurs between the sealing plug 630 and the guide bolt 610, thereby ensuring that the brain electrode passing therethrough does not rotate relative to the guide bolt 610. Figure 7a-7c The electrode fixing device with the first groove according to the embodiment of the present invention is described exemplarily. Further, in order to facilitate understanding of how the sealing plug between the first groove and the nut fixes the brain electrode, the following will be combined with Figure 8 An exemplary description is given.

[0091] Figure 8 Schematic diagram of an electrode fixing device including a deformable sealing plug according to an embodiment of the present invention. Figure 8 As shown in , the electrode fixing device according to the embodiment of the present invention may include a guide bolt 610, a nut 620 and a sealing plug 630, and the brain electrode 110 may sequentially pass through the through-hole structures of the nut 620, the sealing plug 630 and the guide bolt 610. The relative movement between the nut 620 and the guide bolt 610 during connection (e.g., threaded connection) may squeeze the sealing plug 630 therebetween, so that the deformed portion at the lower end of the sealing plug 630 may be inserted into the first groove 612 of the guide bolt 610, so that the brain electrode 110 may be clamped by utilizing the deformation of the sealing plug 630.

[0092] For the sealing plug 630 with uniform upper and lower shapes and constant inner diameter (e.g., hollow cylinder), during its compression and deformation process, the upper end portion 810 of the sealing plug 630 first clamps the brain electrode 110 to be inserted, and as the sealing plug 630 further deforms, the brain electrode 110 may be driven to move downward along the length direction of the brain electrode 110, thereby possibly causing the depth of the brain electrode 110 to change from the original positioning. In scenarios where the positioning accuracy of the brain electrode 110 is required to be high, such as during surgery, such changes may have a certain impact on the use of the brain electrode. Based on the above situation, the inventors have found that by further improving the structure of the electrode fixing device, for example, enabling the sealing plug 630 to radially squeeze the brain electrode 110, the brain electrode 110 can be effectively prevented from moving during the fixing process, thereby solving the problem that the implantation depth of the brain electrode changes during the fixing process of the electrode fixing device. Specifically, according to an embodiment of the present invention, the purpose and effect of radially squeezing the sealing plug 630 can be achieved by improving the shape of the sealing plug 630 and / or the squeezing structure of the sealing plug 630. A detailed description will be given below in conjunction with a number of specific embodiments.

[0093] Fig. 9 Schematic diagram of an electrode fixing device including a second groove according to an embodiment of the present invention. Fig. 9 As shown in , the electrode fixing device according to the embodiment of the present invention may include a guide bolt 610, a nut 620 and a sealing plug 630, wherein the inner side of one end of the guide bolt 610 for connecting with the nut 620 has a first groove 612; and the sealing plug 630 is located between the guide bolt 610 and the nut 620, and the end of the sealing plug 630 facing the guide bolt 610 can be inserted into the first groove 612, and the third through hole 631 of the end of the sealing plug 630 facing the nut 620 has a second groove 920. That is, the second groove 920 can be located at the end of the sealing plug 630 facing the nut 620, and can be connected with the third through hole 631.

[0094] In some embodiments, the shape of the first groove 612 can be adapted to the shape of one end of the sealing plug 630 facing the guide bolt 610 (e.g., the lower end of the sealing plug 630 shown in the figure). In some embodiments, the second groove 920 can be a groove structure that is wide at the top and narrow at the bottom, such as an inverted cone-shaped groove. In other embodiments, the second groove 920 can also be set as a groove with a uniform structure.

[0095] According to such a configuration, during the connection process between the nut 620 and the guide bolt 610, the sealing plug 630 is squeezed and deformed, and the first thing to contact the brain electrode 110 is the lower end surface of the sealing plug 630. Since the lower end surface of the sealing plug 630 is supported by the first groove 612, the bottom of the sealing plug 630 will not continue to move downward, and in the subsequent squeezing process, the subsequent deformation of the sealing plug 630 will be completed by the upper part of the sealing plug 630 (i.e., the location of the second groove 920), so that the brain electrode 110 can be fixed and sealed by the radial squeezing of the brain electrode 110 by the lower part of the sealing plug 630, and the brain electrode 110 will not be driven to move downward, thereby greatly reducing the influence of the deformation of the sealing plug 630 on the positioning of the brain electrode 110.

[0096] Fig.10 Schematic diagram of an electrode fixing device including a fastener according to an embodiment of the present invention. Fig.10 As shown in , the electrode fixing device may include: a guide bolt 610, a nut 620, a sealing plug 630 and a fastener 1010, wherein the fastener 1010 may be located between the guide bolt 610 and the nut 620, and one end 1012 of the fastener 1010 may be integrally formed with the guide bolt 610 or detachably connected, and the other end of the fastener 1010 may include a plurality of baffles 1011 for surrounding the sealing plug 630.

[0097] The fastener 1010 described above can be used to fix the sealing plug 630, and can be fixed between the nut 620 and the guide bolt 610. In some embodiments, the fastener 1010 can be made of rubber, plastic, gum, etc. In other embodiments, the material of the guide bolt 610 can be the same as that of the fastener 1010 to facilitate one-piece molding. For example, the guide bolt 610 and the fastener 1010 can both be made of a tough material such as gum.

[0098] In some other embodiments, the detachable connection between one end 1012 of the fastener 1010 and the guide bolt 610 may include a connection method such as a snap connection, a threaded connection, a plug connection, a bayonet connection, a riveting connection, etc. In some embodiments, one end 1020 of the guide bolt 610 used for connecting with the fastener 1010 may have an inner hexagonal structure; one end 1012 of the fastener 1010 used for connecting with the guide bolt 610 may have an outer hexagonal structure adapted to the inner hexagonal structure, so as to be detachably connected to the guide bolt 610. The outer hexagonal structure adapted to the inner hexagonal structure may include an inner side dimension of the inner hexagonal structure adapted to an outer side dimension of the outer hexagonal structure, so that the two will not rotate relative to each other after being sleeved. According to such a matching arrangement of the inner hexagonal structure and the outer hexagonal structure, it can be ensured that one end 1012 of the fastener 1010 will not rotate relative to each other after being inserted into the guide bolt 610.

[0099] In some embodiments, there may be gaps between the multiple baffles 1011, so that there can be a compressed space between the multiple baffles 1011. In other embodiments, the shape formed by the multiple baffles 1011 may be the same as the shape of the outer surface of the sealing plug 630. For example, in the figure, the multiple baffles 1011 may be formed into a circular ring, so that the cylindrical sealing plug 630 can be placed in the space surrounded by the multiple baffles 1011.

[0100] Furthermore, the inner side of the nut 620 may have an inclined surface that is narrow at the top and wide at the bottom, so as to form radial compression on the multiple baffles 1011 when the nut 620 and the guide bolt 610 are connected. By using the nut 620 in conjunction with the fastener 1010, the rotational deformation provided by the nut 620 can be converted into radial deformation of the sealing plug 630. Fig.11 and Fig.12 The process of the fastener 1010 squeezing the sealing plug 630 is described as an example.

[0101] Fig.11 2 is a schematic diagram showing a state of an electrode fixing device according to an embodiment of the present invention in which multiple baffles are in a relaxed state. Fig.11 As shown in , the electrode fixing device may include a guide bolt 610, a nut 620, a sealing plug 630 and a fastener 1010, wherein the fastener 1010 includes an end 1012 for connecting with the guide bolt 610 and a plurality of baffles 1011, and the inner side of the nut 620 has an inclined surface 1110 that is narrow at the top and wide at the bottom. In some embodiments, the inclined surface 1110 that is narrow at the top and wide at the bottom may be, for example, a conical inclined surface. It should be understood that the narrow at the top and wide at the bottom may refer to that the inner top surface of the nut 620 is relatively narrow, while the inner diameter of the inner side surface extending from the inner top surface of the nut 620 to the end connected with the guide bolt 610 is relatively wide. That is, according to the structural setting of the inner side of the nut 620 being narrow at the top and wide at the bottom, the gap between the plurality of baffles 1011 may undergo a change process from large to small during the connection process between the nut 620 and the guide bolt 610.

[0102] Specifically, Fig.11 As shown in FIG, in the initial stage of connection between the nut 620 and the guide bolt 610, the sealing plug 630 is in a relaxed state in the multiple baffles 1011 and will not deform. At this time, the force point is located at the position 1120 shown in the figure, and the sealing plug 630 has not yet applied force to the brain electrode 110 passing through it. As the nut 620 continues to move toward the guide bolt 610, the following will appear inside the electrode fixing device. Fig.12 The situation shown.

[0103] Fig.122 is a schematic diagram showing the state of an electrode fixing device according to an embodiment of the present invention in which a plurality of baffles squeeze a sealing plug. Fig.12 As shown in , when the nut 620 continues to move downward, the multiple baffles 1011 in the fastener 1010 will first contact the inclined surface 1110 on the inner side of the nut 620, so that the multiple baffles 1011 will be compressed inward, and then squeeze the sealing plug 630 in the radial direction. At this time, the force point is at the position 1210 in the figure, so that the sealing plug 630 is deformed to achieve the function of fixing the brain electrode 110. Further, since the fastener 1010 and the guide bolt 610 can be fixed by the outer hexagonal structure and the inner hexagonal structure, the fastener 1010 will not rotate, so that the sealing plug 630 will only be subjected to the radial force from the multiple baffles 1011, so it will not drive the brain electrode 110 to move downward, so that the positioning of the brain electrode 110 is more accurate.

[0104] Combination of the above Figure 10-12 The electrode fixing device including the fastener is described in detail. It is understood that the provision of the fastener can convert the rotational deformation provided by the nut to the sealing plug into radial deformation, thereby preventing the brain electrode from moving in the axial direction. It is also understood that the implementation method of applying radial force to the sealing plug is not limited to the use of fasteners. In another embodiment of the present invention, the purpose of applying radial force to the sealing plug can also be achieved by, for example, providing a cavity. Figure 13-Figure 16 An exemplary description is given.

[0105] Fig.13 Schematic diagram of an electrode fixing device including a cavity according to an embodiment of the present invention. Fig.13 As shown in , the electrode fixing device may include: a guide bolt 610, a nut 620, a sealing plug 630 and a cavity 1310, wherein the cavity 1310 may be located at the top of the nut 620 and has an inner cavity 1311 for placing the sealing plug 630, so as to radially squeeze the sealing plug 630 when the space of the inner cavity 1311 is compressed. By arranging the cavity 1310 at the top of the nut 620, the sealing plug 630 may be fixed to the top of the nut 620, thereby preventing the nut 620 from rotating and squeezing the sealing plug 630.

[0106] In some embodiments, the cavity 1310 may be connected to the nut 620, or may be provided separately without being connected to the nut 620. The top of the nut 620 is the end of the nut 620 that is not connected to the guide bolt 610. By providing an inner cavity 1311 for placing the sealing plug 630, and because the sealing plug 630 has a hollow structure, the brain electrode can pass through the sealing plug 630 and the cavity 1310, so as to achieve the purpose of radially fixing the brain electrode through the cavity 1310. In other embodiments, the spatial shape and volume of the inner cavity 1311 can be adapted to the sealing plug 630, so that the sealing plug 630 can be placed exactly in the inner cavity 1311, and there will not be too much gap between the sealing plug 630 and the inner wall of the inner cavity 1311, which is conducive to ensuring the effectiveness of the force applied by the cavity 1310 to the sealing plug 630.

[0107] like Fig.13 As further shown in FIG. 1 , in another embodiment of the present invention, the mold cavity 1310 may include a fastening baffle and a movable baffle, wherein the fastening baffle may have a threaded hole, and the movable baffle may have a fourth through hole; and the electrode fixing device may further include: a fastening screw 1320, which may be used to compress the inner cavity 1311 space of the mold cavity 1310 when passing through the fourth through hole to be threadedly connected with the threaded hole. Fig.14 and Fig.15 The fastening block and the moving block are described exemplarily.

[0108] Fig.14 is a top view showing a cavity according to an embodiment of the present invention. Fig.15 2 is a cross-sectional view showing a cavity when a fastening screw passes through a through hole to be threadedly connected with a threaded hole according to an embodiment of the present invention. Fig.14 and Fig.15 As shown in , the mold cavity 1310 may include a fastening baffle 1410 and a moving baffle 1420, wherein the fastening baffle 1410 may be used for fixing, and the moving baffle 1420 may be used to move toward the fastening baffle 1410 to compress the inner cavity space of the mold cavity 1310. In some embodiments, the thickness of the fastening baffle 1410 may be greater than the thickness of the moving baffle 1420.

[0109] The fastening baffle 1410 may have a threaded hole 1510, and the movable baffle 1420 may have a fourth through hole 1520. The fastening screw passes through the fourth through hole 1520 on the movable baffle 1420 and is tightened in cooperation with the threaded hole 1510 of the fastening baffle 1410, so that the movable baffle 1420 will be compressed. At this time, the sealing plug in the cavity 1310 will be deformed by the extrusion force from all sides, but will not be subjected to the rotational pressure from the nut 620.

[0110] Those skilled in the art will appreciate that the above description is illustrative rather than restrictive. For example, it is not limited to having a threaded hole on the fastening baffle and a through hole on the movable baffle. Both the fastening baffle and the movable baffle may be provided with through holes, and the fastening screws may pass through the respective through holes on the movable baffle and the fastening baffle and then cooperate with the nuts to achieve the purpose of compressing the movable baffle 1420.

[0111] Fig.16 Schematic diagram showing a connection portion according to an embodiment of the present invention. Fig.16 As shown in the figure, the cavity 1310 and the nut 620 can be connected by a connecting portion 1610, and a first connecting surface 1611 connecting the connecting portion 1610 and the nut 620 can be smaller than a cross-section 1620 of the nut 620; and / or a second connecting surface 1612 connecting the connecting portion 1610 and the cavity 1310 can be smaller than a cross-section 1630 of the cavity 1310.

[0112] The first connection surface 1611 of the connection portion 1610 may be a connection surface between the connection portion 1610 and the nut 620. The cross section 1620 of the nut 620 may be a top surface of the nut 620. The second connection surface 1612 of the connection portion 1610 may be a connection surface between the connection portion 1610 and the cavity 1310. The cross section 1630 of the cavity 1310 may be a bottom surface of the cavity 1310. In some embodiments, the shape and size of the first connection surface 1611 may be the same as or different from the shape and size of the second connection surface 1612.

[0113] In other embodiments, the size of the second connection surface 1612 may be smaller than the size of the cross section 1630 of the cavity 1310. According to such a configuration, the restriction of the second connection surface 1612 on the deformation of the cavity 1310 may be reduced, thereby facilitating the increase in the deformation of the cavity 1310 relative to the second connection surface 1612. In still other embodiments, the size of the first connection surface 1611 may be smaller than the size of the cross section 1620 of the nut 620. According to such a configuration, the restriction of the first connection surface 1611 on the deformation of the cavity 1310 may be reduced, thereby facilitating the increase in the deformation of the cavity 1310 relative to the first connection surface 1611.

[0114] In some embodiments, the connection portion 1610 can be configured as a narrow connection structure, wherein the first connection surface 1611 is smaller than the cross section 1620 of the nut 620, and the second connection surface 1612 is smaller than the cross section 1630 of the cavity 1310. According to such a configuration, the restriction of the first connection surface 1611 on the deformation of the cavity 1310 can be reduced, and the restriction of the second connection surface 1612 on the deformation of the cavity 1310 can also be reduced, so as to more significantly increase the deformation of the cavity 1310 and make the cavity 1310 squeeze the sealing plug more tightly.

[0115] Through the above description of the technical solution and multiple embodiments of the device for electroencephalogram monitoring and treatment of the present invention, those skilled in the art can understand that the device of the embodiment of the present invention can transmit the electroencephalogram signal to the electroencephalograph by setting an interface device, and fix the brain electrodes by setting an electrode fixing device, so as to ensure the stability and reliability of electroencephalogram signal detection and transmission during the electroencephalogram monitoring process.

[0116] In some embodiments, the setting of the limiting portion can prevent the electrode fixing device from excessively rotating when fixed on the skull. In other embodiments, by setting the sealing plug for radial extrusion, the sealing plug can be prevented from moving the brain electrode while fixing the brain electrode, and the extrusion of the sealing plug can also achieve a sealing effect to prevent brain tissue fluid from overflowing from the through-hole structure of the sealing plug. In some other embodiments, by setting the first protrusion and the second protrusion, the side insertion of the first end and the second end can be achieved, and the connection between the first end and the second end can be made tighter, so as to effectively reduce the risk of the first end or the second end falling off due to external force, thereby ensuring that the surgical procedure will not be interrupted.

[0117] Although the embodiments of the present invention are described above, the contents are only embodiments used to facilitate understanding of the present invention, and are not intended to limit the scope and application scenarios of the present invention. Any technician in the technical field of the present invention can make any modifications and changes in the form and details of the implementation without departing from the spirit and scope disclosed by the present invention, but the scope of patent protection of the present invention shall still be based on the scope defined by the attached claims.

Claims

1. A device for electroencephalogram monitoring and treatment, comprising: Brain electrodes for detecting brain electrical signals and / or performing thermal coagulation therapy; An interface device, one end of which is connected to the brain electrode, and the other end of which is used to connect to an electroencephalograph and / or a radiofrequency thermocoagulation generator, so as to transmit the electroencephalogram signal to the electroencephalograph and / or receive a control signal sent from the radiofrequency thermocoagulation generator; as well as An electrode fixing device is used to fix the brain electrode when the brain electrode is implanted in the skull; wherein the electrode fixing device comprises: A guide bolt, which is used to be fixed on the skull and has a first through hole; a nut, which is used to be connected with the guide bolt and has a second through hole; and A sealing plug, which is located between the guide bolt and the nut, or located on the top of the nut, and has a third through hole; The first through hole, the second through hole and the third through hole are used for the brain electrode to pass through, so as to fix the brain electrode; When the sealing plug is located between the guide bolt and the nut, the guide bolt has a first groove at the first through hole at one end thereof for connecting with the nut, and the sealing plug is inserted into the first groove toward one end of the guide bolt; or the electrode fixing device also includes a fastener, which is located between the guide bolt and the nut and is used to fix the sealing plug.

2. The device according to claim 1, wherein the interface device comprises: A first end portion having a first interface surface and a first convex portion on one side of the first interface surface; and The second end has a second interface surface that is adapted to the shape of the first interface surface, and has a second convex portion on one side of the second interface surface, so that when the second interface surface is connected to the first interface surface, the first convex portion and the second convex portion are respectively located on both sides of the connection.

3. The device according to claim 2, wherein The other side of the first interface surface has a first end surface opposite to the protruding direction of the first protrusion, and the first end surface is adapted to the inner side surface of the second protrusion; and The other side of the second interface surface has a second end surface opposite to the protruding direction of the second protrusion, and the second end surface is adapted to the inner side surface of the first protrusion.

4. The device according to claim 2, wherein The first interface surface is rectangular, and the first convex portion is located on a short side of the first interface surface; and The second interface surface is rectangular, and the second convex portion is located on one side of a short side of the second interface surface.

5. The device according to claim 3, wherein The first interface surface is rectangular, and the first convex portion is located on a short side of the first interface surface; and The second interface surface is rectangular, and the second convex portion is located on one side of a short side of the second interface surface.

6. The device according to any one of claims 2 to 5, wherein The first end portion further has a first connection port, which is located on the outer side of the first protrusion relative to the first interface surface, for connecting to an electroencephalograph; and The second end portion also has a second connection port, which is located on the outer side of the second protrusion relative to the second interface surface, for connecting with the brain electrode.

7. The device according to any one of claims 2 to 5, wherein The first interface surface has a first plugging area, and the first plugging area is provided with plug pins; and The second interface surface has a second plugging area, and the second plugging area is provided with slots corresponding to the plug pins one by one for plugging with the plug pins.

8. The device according to claim 7, wherein The first plugging area is recessed in the first interface surface; and The second plugging area protrudes from the second interface surface, and a protruding height of the second plugging area is equal to a recessed depth of the first plugging area.

9. The device according to claim 7, wherein the interface device further comprises: at least one guide groove disposed at an edge of one of the first plugging area and the second plugging area; as well as At least one guide block corresponds to the at least one guide groove one by one and is disposed at an edge of the other of the first plug-in area and the second plug-in area.

10. The device according to claim 8, wherein the interface device further comprises: at least one guide groove disposed at an edge of one of the first plugging area and the second plugging area; as well as At least one guide block corresponds to the at least one guide groove one by one and is disposed at an edge of the other of the first plug-in area and the second plug-in area.

11. The device according to claim 2, wherein A first anti-slip convex point is arranged on the outer surface of the first end portion; and / or A second anti-slip protrusion is arranged on the outer surface of the second end portion.

12. The device according to claim 1, wherein A limiting portion is provided on the guide bolt, and the limiting portion is close to one end of the guide bolt for inserting into the skull.

13. The device according to claim 12, wherein The guide bolt is provided with a clamping portion, which is located between one end of the guide bolt used for connecting with the nut and the limiting portion.

14. The device according to claim 1, 12 or 13, wherein The first groove is a hexagonal structure; and One end of the sealing plug for inserting into the first groove has an external hexagonal structure adapted to the first groove, or the sealing plug has the external hexagonal structure as a whole.

15. The device according to claim 13, wherein The sealing plug has a second groove at the third through hole at one end facing the nut.

16. The device according to claim 1, 12 or 13, wherein one end of the fastener is integrally formed with or detachably connected to the guide bolt, and the other end thereof comprises a plurality of baffles for surrounding the sealing plug; and The inner side of the nut has an inclined surface which is narrow at the top and wide at the bottom, so as to form radial compression on the multiple baffles when the nut is connected to the guide bolt.

17. The device according to claim 16, wherein One end of the guide bolt used for connecting with the fastener has a hexagonal structure; One end of the fastener used for connecting with the guide bolt has an outer hexagonal structure adapted to the inner hexagonal structure so as to be detachably connected with the guide bolt.

18. The device according to claim 1, wherein the electrode fixing device further comprises: The mold cavity is located at the top of the nut and has an inner cavity for placing the sealing plug so as to radially squeeze the sealing plug when the inner cavity space is compressed.

19. The device according to claim 18, wherein The mold cavity comprises a fastening baffle and a moving baffle, the fastening baffle has a threaded hole, and the moving baffle has a fourth through hole; and The electrode fixing device also includes: A fastening screw is used to compress the inner cavity space of the cavity when passing through the fourth through hole to be threadedly connected with the threaded hole.

20. The device according to claim 18 or 19, wherein the cavity is connected to the nut via a connecting portion, and The first connection surface between the connecting portion and the nut is smaller than the cross section of the nut; and / or A second connection surface where the connection portion is connected to the cavity is smaller than a cross section of the cavity.

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