An ultrasonic catheter and ultrasonic treatment device

Abstract

The application provides an ultrasonic catheter and ultrasonic treatment device, which comprises a guide catheter with a central cavity, a treatment catheter arranged in the central cavity and extending along the longitudinal direction of the guide catheter, a plurality of transducer assemblies arranged outside the distal end of the treatment catheter and formed in the central cavity, and a plurality of developing support assemblies longitudinally sleeved on the treatment catheter and formed in the central cavity and spaced apart from the transducer assemblies; the developing support assembly comprises a bending part formed by continuously bending along the longitudinal direction to form a plurality of staggered ribs, and the adjacent ribs are separated along the longitudinal direction. The application provides an ultrasonic catheter and ultrasonic treatment device, which can avoid damaging the blood vessel during the process of inserting the ultrasonic catheter into the blood vessel for treatment, and the ultrasonic catheter is easy to pass through the bending part of the blood vessel.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, more particularly to an ultrasonic catheter and an ultrasonic treatment device. BACKGROUND

[0002] A thrombus is a small mass of blood clots that forms on the surface of a blood vessel in the cardiovascular system at a site of peeling or repair. Thrombosis is the common pathogenesis of the top three global fatal cardiovascular diseases: myocardial infarction, stroke and venous thromboembolism.

[0003] Ultrasonic thrombolysis technology refers to a clinical treatment technology that uses the cavitation effect and mechanical stress of low-frequency high-energy ultrasound to crush blood clots and hardened plaques into micron-sized small particles, and allows these small particles to be removed along with the body metabolism, thereby recanalizing the occluded blood vessels. It has the characteristics of high thrombolysis efficiency and good safety, and can significantly reduce the dosage of thrombolytic drugs and greatly reduce the risk of complications such as intravascular hemorrhage and neurological damage, showing an attractive application prospect. Ultrasonic thrombolysis technology needs to use an ultrasonic treatment device, and the ultrasonic catheter as an important component of the ultrasonic treatment device still has some deficiencies.

[0004] The ultrasonic transducer included in the ultrasonic catheter in the prior art has the defect of high rigidity and is not easy to bend, thereby causing the ultrasonic catheter to easily damage the blood vessel during insertion into the blood vessel and not easy to pass through the bending part of the blood vessel.

[0005] Therefore, it is necessary to improve the ultrasonic catheter in the prior art to solve the above problems. SUMMARY

[0006] The purpose of the present application is to disclose an ultrasonic catheter and an ultrasonic treatment device to solve the many defects of the ultrasonic catheter in the prior art, and in particular to solve the problem that the existing ultrasonic catheter has high rigidity, is easy to damage the blood vessel, and is not easy to pass through the bending part of the blood vessel.

[0007] To achieve the above purpose, the present application provides an ultrasonic catheter, comprising:

[0008] a guide catheter having a central cavity, a treatment catheter arranged in the central cavity and extending along the longitudinal direction of the guide catheter, a plurality of transducer assemblies arranged outside the distal end of the treatment catheter and formed in the central cavity, and a plurality of imaging support assemblies arranged in the central cavity and spaced apart from the transducer assemblies and longitudinally sleeved on the treatment catheter.

[0009] The imaging support assembly comprises a bending portion formed by continuously bending in the longitudinal direction to form a plurality of staggered ribs, and the adjacent ribs are separated in the longitudinal direction.

[0010] As a further improvement of the present invention, the ribs include:

[0011] A first rod portion, a second rod portion arranged parallel to the first rod portion, and a third rod portion longitudinally connecting the first rod portion and the second rod portion.

[0012] As a further improvement of the present invention, the third rod portion forms an arc portion with the first rod portion and the second rod portion respectively, and the radius of the arc portion is 0.1-0.2 mm.

[0013] As a further improvement of the present invention, the width of the first rod portion and the second rod portion along the longitudinal direction is 0.1-0.5 mm.

[0014] As a further improvement of the present invention, a width formed between the first rod portion and the second rod portion along the longitudinal direction is 0.1-0.5 mm.

[0015] As a further improvement of the present invention, the developing support assembly further includes: a connecting portion connected to the bending portion.

[0016] As a further improvement of the present invention, the wall thickness of the connecting portion is 0.1 to 0.3 mm.

[0017] As a further improvement of the present invention, the length of the developing support assembly is 0.5 to 1 cm.

[0018] As a further improvement of the present invention, the transducer assembly includes:

[0019] Negative connecting plate;

[0020] and a first transducer and a second transducer arranged back to back on the negative connecting plate, or a first transducer and a first transducer arranged back to back on the negative connecting plate, or a second transducer and a second transducer arranged back to back on the negative connecting plate.

[0021] Based on the same inventive concept, the present invention also discloses an ultrasonic treatment device, comprising: a liquid inlet device, an ultrasonic catheter disclosed in any of the aforementioned inventions connected to the liquid inlet device, and a control system for controlling the ultrasonic catheter.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] By providing a bending portion, which is composed of a plurality of staggered longitudinally continuously bent ribs, when the ultrasonic catheter is inserted into a blood vessel and interventional treatment is performed on the lesion, the bending portion can bend, thereby increasing the flexibility of the ultrasonic catheter, making the ultrasonic catheter both rigid and flexible, thereby preventing the ultrasonic catheter from damaging the blood vessel during insertion during treatment, and making it easier for the ultrasonic catheter to pass through the bend of the blood vessel. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 A three-dimensional diagram of a development support assembly included in an ultrasonic catheter of the present invention;

[0025] Figure 2 A diagram showing the connection structure between the development support assembly and the isolation structure;

[0026] Figure 3 A stereoscopic diagram of an ultrasonic catheter according to the present invention;

[0027] Figure 4 for Figure 3 A cross-sectional view of the isolation structure;

[0028] Figure 5 is a three-dimensional diagram of the ultrasonic treatment device of the present invention;

[0029] Figure 6 for Figure 5 Right side view of the guide catheter. DETAILED DESCRIPTION

[0030] The present invention is described in detail below with reference to the various embodiments shown in the accompanying drawings, but it should be noted that these embodiments are not limitations of the present invention, and any equivalent transformations or substitutions in functions, methods, or structures made by ordinary technicians in this field based on these embodiments are all within the scope of protection of the present invention.

[0031] It should be understood that the terms "longitudinal", "transverse", "length", "width", "inner", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present technical solution and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present technical solution. If the full text involves descriptions such as "first" and "second", the descriptions such as "first" and "second" are only used to distinguish similar objects, and cannot be understood as indicating or implying their relative importance, order, or implicitly indicating the number of the technical features indicated. It should be understood that the numbers described as "first" and "second" can be interchanged under appropriate circumstances.

[0032] The ultrasound catheter described herein can be used for deep vein thrombosis (DVT) in the lower limbs. In other embodiments, the ultrasound catheter can also be used to treat pulmonary embolism (PE) and post-phlebitic syndrome (PTS). However, it should be understood that certain features and aspects of the present embodiment can be applied to catheters configured to be inserted into other vessels or cavities (such as small cerebral vessels, solid tissues, duct systems, and body cavities). For example, in the treatment of DVT, during the treatment process, the ultrasound catheter needs to be inserted into the thrombus through the iliofemoral vein, and at the same time, thrombolytic drugs such as urokinase or streptokinase are injected through the side cavity of the guide catheter to dissolve the thrombus. For example, in the early stages of acute myocardial infarction, drugs with thrombolytic effects are used to dissolve the thrombus and recanalize the coronary artery for treatment. The right coronary artery originates from the right aortic sinus, passes between the right atrial appendage and the root of the pulmonary artery, enters the coronary sulcus and runs to the right, forming an inverted "U"-shaped curved structure at the atrioventricular intersection. When treating acute myocardial infarction, the use of this new type of ultrasonic catheter can easily pass through the bends of the blood vessels and avoid damaging the blood vessels during the insertion of the ultrasonic catheter.

[0033] Please refer to Figures 1 to 6 A specific embodiment of the disclosed ultrasonic catheter includes a guide catheter 11 having a central cavity 110, a guide tube 11 disposed in the central cavity 110 and extending longitudinally along the guide catheter 11 (ie, Figure 3 A treatment catheter 10 extending in the direction of (a in the middle), a plurality of transducer assemblies 20 are arranged on the outside of the distal end of the treatment catheter 10 (wherein the distal end refers to the end for treating thrombus) and formed in the central cavity 110, and a plurality of development support assemblies 25 are longitudinally sleeved on the treatment catheter 10 and formed in the central cavity 110 and spaced apart from the transducer assemblies 20; the development support assembly 25 includes a plurality of staggered ribs 254 formed by continuous bending in the longitudinal direction, and adjacent ribs 254 are separated along the longitudinal direction.

[0034] By providing a bending portion 253, and the bending portion 253 is composed of a plurality of staggered longitudinally continuously bent ribs 254, when the ultrasonic catheter is inserted into a blood vessel, the bending portion 253 can bend, thereby increasing the flexibility of the ultrasonic catheter, so that the ultrasonic catheter has both rigidity and flexibility, thereby avoiding damage to the blood vessel during the insertion of the ultrasonic catheter into the blood vessel during vascular interventional treatment, and the ultrasonic catheter can easily pass through the bend of the blood vessel.

[0035] Among them, such as Figure 3As shown, the elongated guide catheter 11 is made of a flexible material, such as polytetrafluoroethylene, polyethylene, polyamide and other similar materials, but not limited to such materials. The guide catheter 11 has a distal end 12 and a proximal end 13 (the distal end 12 is the end for treating thrombus; the proximal end 13 is the end for surgical operation). The guide catheter 11 and other components of the ultrasonic catheter can be manufactured according to any of the various technologies well known in the field of catheter manufacturing. Appropriate materials and sizes can be selected based on the treatment, and the shape of the cross section of the guide catheter 11 can be circular, square or other irregular shapes. In some embodiments configured for treating thrombosis in the veins of the lower limbs, the length of the guide catheter 11 is 10 cm-200 cm, for example, preferably an axial length of 106 cm to 135 cm, and the specific length is determined according to the length required for treatment.

[0036] Preferably, Figure 3 and Figure 6 As shown, the guide catheter 11 adopts a multi-cavity configuration, including a central cavity 110 extending along the extension direction of the guide catheter 11 and at least one sub-cavity arranged on the periphery of the central cavity 110. In this embodiment, three sub-cavities are arranged on the periphery of the central cavity 110, including a first sub-cavity 112, a second sub-cavity 113 and a third sub-cavity 114. The first sub-cavity 112, the second sub-cavity 113 and the third sub-cavity 114 are all arranged in the extension direction of the guide catheter 11 (i.e., Figure 3 The central cavity 110 is used to accommodate the treatment catheter 10, including the transducer assembly 20, the imaging support assembly 25, and the injection of physiological saline. The first sub-cavity 112, the second sub-cavity 113, and the third sub-cavity 114 are respectively used to accommodate thermocouples and simultaneously inject physiological saline and thrombolytic agents.

[0037] Among them, Figure 2 and Figure 3As shown, the imaging support assembly 25 and the transducer assembly 20 are spaced apart. Specifically, the imaging support assembly 25 is disposed between two adjacent transducer assemblies 20, ensuring that the ultrasound catheter is both rigid and flexible. This facilitates the catheter's advancement within the vessel and its passage through bends during insertion and treatment of lesions. In a preferred embodiment, the treatment catheter 10 equipped with the transducer assembly 20 extends through the imaging support assembly 25, and the guide catheter 11 is sheathed with the transducer assembly 20, the treatment catheter 10, and the imaging support assembly 25. The first end 28 and the second end 27 of the transducer assembly 20 are plugged into the development support assembly 25, and the connection portion 251 of the development support assembly 25 is reliably connected to the first end 27 of the transducer assembly 20 and is sealed with epoxy resin. The second end 28 of the transducer assembly 20 and the connection portion 251 of the adjacent development support assembly 25 are sealed with epoxy resin, which can not only ensure the rigidity of the transducer assembly 20, but also increase the flexibility of the transducer assembly 20. On the basis of ensuring the rigidity of the ultrasonic catheter, the flexibility is increased, so that when the ultrasonic catheter is inserted into the blood vessel and interventional treatment is performed on the lesions in the blood vessel, it is not only convenient for the ultrasonic catheter to advance in the blood vessel, but also enables the ultrasonic catheter to easily pass through the bends of the blood vessel.

[0038] Preferably, Figure 1 As shown, the imaging support assembly 25 also includes a connecting portion 251 connected to the bend 253. The provision of the connecting portion 251 increases the overall rigidity of the imaging support assembly 25, facilitating the advancement of the ultrasound catheter within the blood vessel. The connecting portion 251 can be configured as a cylindrical structure with an opening 252 or a cylindrical structure without an opening 252. To avoid damaging the blood vessel during interventional treatment by inserting the ultrasound catheter through the blood vessel, the connecting portion 251 can be configured as a substantially cylindrical structure. The connecting portion 251 and the bend 253 form an integral structure. The connecting portion 251 and the bend 253 are made of the same material. The increased flexibility of the connecting portion 251 and the bend 253 facilitates the advancement of the ultrasound catheter within the blood vessel during insertion and interventional treatment of lesions therein. This not only facilitates the advancement of the ultrasound catheter within the blood vessel, but also allows the ultrasound catheter to easily and smoothly pass through the bends of the blood vessel.

[0039] In addition, the connecting portion 251 and the bending portion 253 can be made of nickel-titanium alloy, gold, silver and other materials. Since nickel-titanium alloy, gold, silver and other metals or alloy materials have a developing effect, the developing performance of the ultrasound catheter can be increased. When the ultrasound catheter is inserted into the blood vessel and interventional treatment is performed on the lesions in the blood vessel, it not only facilitates the advancement of the ultrasound catheter in the blood vessel, but also enables the ultrasound catheter to easily pass through the bends of the blood vessel, and can accurately determine whether the ultrasound catheter has reached the optimal position for treating thrombus.

[0040] The connecting portion 251 and the bending portion 253 may be made of the same material or different materials.

[0041] Preferably, considering the difficulty and cost of manufacturing, the connecting portion 251 and the bending portion 253 are made of the same material, namely nickel-titanium alloy. The specific formula is:

[0042] The atomic fraction of Ni content is 51.0%-60.0%;

[0043] The atomic fraction of Co content is 0.01%-0.1%;

[0044] The atomic fraction of Cu content is 0.01%-0.05%;

[0045] The atomic fraction of Fe content is 0.01%-0.05%;

[0046] The atomic fraction of H content is 0.001%-0.01%;

[0047] The atomic fraction of O content is 0.01%-0.1%;

[0048] and, the balance titanium.

[0049] From the perspective of the rigidity and flexibility of nickel-titanium alloy, the average grain size is level 4 or 5.

[0050] The preparation method of nickel-titanium alloy can be obtained by the method in the prior art, preferably by selective laser melting. Figure 1 , the wall thickness of the connecting portion 251 (ie, Figure 1 The thickness of d1 shown in FIG is 0.1 to 0.3 mm. The wall thickness of the connecting portion 251 can be any value between 0.1 and 0.3 mm, as long as it can increase the rigidity of the bending portion 253. For example, the wall thickness of the connecting portion 251 can be 0.1 mm, 0.2 mm, or 0.3 mm. In this embodiment, it is preferably 0.2 mm. By setting the wall thickness of the connecting portion 251 to 0.2 mm, not only can the connecting portion 251 have a certain degree of rigidity, but also the entire imaging support assembly 25 has a certain degree of elasticity, so that the ultrasonic catheter has both rigidity and elasticity. When the ultrasonic catheter is inserted into a blood vessel and performs interventional treatment on a lesion in the blood vessel, it not only facilitates the advancement of the ultrasonic catheter in the blood vessel, but also allows the ultrasonic catheter to easily pass through the bends of the blood vessel. The length of the imaging support assembly 25 is 0.5 to 1 cm. The length of the imaging support assembly 25 can be any value between 0.5 and 1 cm, for example, 0.5 cm, 0.7 cm, or 1 cm can be selected. The length of the imaging support assembly 25 can be selected according to the actual treatment situation.

[0051] Preferably, continue to refer to Figure 1 As shown, the rib portion 254 includes a first rod portion 2541, a second rod portion 2542 arranged parallel to the first rod portion 2541, and a third rod portion 2543 longitudinally connecting the first rod portion 2541 and the second rod portion 2542. The first rod portion 2541 and the second rod portion 2542 can be configured in various shapes, such as arcuate or linear. However, to avoid damage to the blood vessel during insertion of the ultrasound catheter for interventional treatment of lesions and to facilitate advancement of the ultrasound catheter within the blood vessel, in this embodiment, the first rod portion 2541 and the second rod portion 2542 are configured in an arcuate structure, and the bent portion 253 formed by the plurality of rib portions 254 is approximately cylindrical.

[0052] Preferably, continue to participate Figure 1 The third rod portion 2543 forms an arc portion 2544 with the first rod portion 2541 and the second rod portion 2542 respectively. The purpose of providing the arc portion 2544 is to relieve stress concentration. The so-called stress concentration refers to the phenomenon of local stress increase in an object, which generally occurs in places where the shape of the object changes sharply. For example, when the bending portion 253 in this embodiment is bent, stress concentration can cause fatigue cracks in the object. In this embodiment, the bending portion 253 is cracked or static load fracture occurs. The radius of the arc portion 2544 is 0.1 to 0.2 mm. The radius of the arc portion 2544 can be any value between 0.1 and 0.2 mm, for example, 0.1 mm or 0.2 mm, as long as it can relieve the concentrated stress of the bending portion 253. In this embodiment, when the radius of the arc portion 2544 is 0.1-0.2 mm, the stress concentration problem can be relieved to the greatest extent.

[0053] Preferably, Figure 1 、 Figure 3 and Figure 5 As shown, the width of the first rod portion 2541 and the second rod portion 2542 along the longitudinal direction is 0.1 to 0.5 mm. The width of the first rod portion 2541 and the second rod portion 2542 along the longitudinal direction can be any value from 0.1 to 0.5 mm, for example, 0.1 mm, 0.2 mm or 0.5 mm. The width formed between the first rod portion 2541 and the second rod portion 2542 along the longitudinal direction (i.e., Figure 1 The width of d2 in the longitudinal direction is 0.1 to 0.5 mm. The width formed between the first rod portion 2541 and the second rod portion 2542 in the longitudinal direction can be any value between 0.1 and 0.5 mm, for example, 0.1 mm, 0.2 mm, or 0.5 mm. For example, in this embodiment, the width of the first rod portion 2541 and the second rod portion 2542 in the longitudinal direction is set to 0.2 mm, and the width between the first rod portion 2541 and the second rod portion 2542 in the longitudinal direction is set to 0.2 mm.

[0054] In a preferred embodiment, Figure 5 The rotating device 17 is provided in the middle, and the rotating device 17 can drive the treatment catheter along Figure 1 The axis b shown in the figure rotates 360 degrees, and the ultrasound catheter can bend 180 degrees. When the ultrasound catheter is inserted into a blood vessel for interventional treatment of a lesion, it can accurately determine whether the ultrasound catheter has reached the optimal position for treating a thrombus. This also allows for greater flexibility in the ultrasound catheter, making it easier to navigate through bends in the blood vessel.

[0055] Similarly, based on any of the ultrasonic catheters disclosed in the aforementioned embodiments, this embodiment also discloses an ultrasonic treatment device.

[0056] Ginseng Figure 5 As shown, the ultrasonic treatment device includes a fluid inlet device 15, an ultrasonic catheter connected to the fluid inlet device 15, and a control system 16 for controlling the ultrasonic catheter. The fluid inlet device 15 includes a plurality of fluid inlets, through which fluid is injected into the proximal end 13 of the ultrasonic catheter. In some embodiments, the fluid inlet device 15 may include a drug inlet, a saline inlet, etc. In some embodiments, in order to provide an electrical connection with the transducer assembly 20, the ultrasonic catheter may further include a wire 26, which may be electrically connected to the control system 16 at the proximal end 13 through a proximal inlet port (not shown).

[0057] Preferably, Figures 2 to 4 As shown, the transducer assembly 20 includes a negative connecting plate (not shown); and a first transducer and a second transducer arranged back to back on the negative connecting plate, or a first transducer and a first transducer arranged back to back on the negative connecting plate, or a second transducer and a second transducer arranged back to back on the negative connecting plate. A first electrical connection plate 231 is arranged between the first transducer 21 and the treatment catheter 10, and a second electrical connection plate 232 is arranged between the second transducer 22 and the treatment catheter 10. Each group of transducer assemblies includes an ultrasonic treatment transducer and an ultrasonic imaging transducer. The first electrical connection plate 231 and the second electrical connection plate 232 are connected to their respective corresponding negative connecting plates, and are connected to the control system 16. In view of the fact that the control system 16 is not the invention point of the present application, it is omitted in this embodiment. Preferably, reference Figure 4 As shown, a treatment catheter 10 is provided between the first transducer 21 and the second transducer 22 to achieve isolation of the two groups of ultrasonic waves through the treatment catheter 10, thereby avoiding mutual interference between the ultrasonic waves emitted by the two ultrasonic transducers, so that the ultrasonic treatment device manufactured thereby has a higher anti-interference ability and a higher treatment accuracy.

[0058] Continue to participate Figure 4As shown, the treatment catheter 10 can be configured as a plate-like structure having a cavity 240. For example, the cavity 240 can be filled with gas or tungsten-containing epoxy resin, or the cavity 240 can be directly configured as a vacuum cavity structure. In another embodiment, the treatment catheter 10 is a solid plate-like structure. The material of the treatment catheter 10 can be made of a highly elastic material such as nickel-titanium alloy, gold, silver, etc., which can further increase the flexibility of the ultrasonic catheter and make it easier for the ultrasonic catheter to pass through the bends of the blood vessels. The series of detailed descriptions listed above are only specific descriptions of the feasible implementation methods of the present invention. They are not intended to limit the scope of protection of the present invention. All equivalent implementation methods or changes that do not deviate from the technical spirit of the present invention should be included in the scope of protection of the present invention.

[0059] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. An ultrasonic catheter, characterized in that: include: A guide catheter having a central cavity, a treatment catheter disposed in the central cavity and extending longitudinally of the guide catheter, a plurality of transducer assemblies disposed outside the distal end of the treatment catheter and formed in the central cavity, and a plurality of imaging support assemblies longitudinally sleeved on the treatment catheter and formed in the central cavity and spaced apart from the transducer assemblies. The developing support assembly includes a bending portion formed by continuous bending along the longitudinal direction to form a plurality of staggered ribs with adjacent ribs separated along the longitudinal direction, and a connecting portion connecting the bending portion. The end portions of the transducer assembly along its longitudinal extension direction and the connecting portion of the developing support assembly adjacent to the transducer assembly are sealed with epoxy resin.

2. The ultrasonic catheter according to claim 1, wherein The ribs include: A first rod portion, a second rod portion arranged parallel to the first rod portion, and a third rod portion longitudinally connecting the first rod portion and the second rod portion.

3. The ultrasonic catheter according to claim 2, characterized in that The third rod portion forms an arc portion with the first rod portion and the second rod portion respectively, and the radius of the arc portion is 0.1-0.2 mm.

4. The ultrasonic catheter according to claim 2, wherein The width of the first rod portion and the second rod portion along the longitudinal direction is 0.1-0.5 mm.

5. The ultrasonic catheter according to claim 4, characterized in that A width formed between the first rod portion and the second rod portion along the longitudinal direction is 0.1 to 0.5 mm. The ultrasonic catheter according to claim 1 , wherein: The wall thickness of the connecting portion is 0.1 to 0.3 mm.

7. The ultrasound catheter according to any one of claims 1 to 6, characterized in that The length of the developing support assembly is 0.5 to 1 cm.

8. The ultrasonic catheter according to claim 1, wherein The transducer assembly comprises: Negative connecting plate; and a first transducer and a second transducer arranged back to back on the negative connecting plate, or a first transducer and a first transducer arranged back to back on the negative connecting plate, or a second transducer and a second transducer arranged back to back on the negative connecting plate.

9. An ultrasonic treatment device, characterized in that: include: A liquid inlet device, an ultrasonic catheter according to any one of claims 1 to 8 connected to the liquid inlet device, and a control system for controlling the ultrasonic catheter.

Images