Blood purification equipment and storage media

Abstract

The present application discloses a blood purification device and a storage medium, the device including: a memory and a processor, the memory is used to store a computer program; the processor is used to execute the computer program and implement the following method: when it is detected that the continuous purification time of the blood purifier is equal to a first preset time, the pressure of the blood circuit is detected to obtain a standard pressure value; the pressure alarm range of the blood circuit is determined according to the standard pressure value; when it is detected that the continuous purification time of the blood purifier is greater than the first preset time, the pressure of the blood circuit is detected to obtain a pressure detection value; according to the pressure detection value and the pressure alarm range, it is determined whether the pressure of the blood circuit is faulty. In this way, the present application can provide a judgment standard for pressure faults with higher rationality and scientificity, reduce judgment errors, and ensure the safe operation of the blood purification device.

Description

Technical Field

[0001] The present application relates to the technical field of blood purification, and in particular to a blood purification device and a storage medium. Background Art

[0002] During blood purification treatment, various blood purification parameters (such as the pressure of the blood purification circuit) need to be tested to monitor the safety of the patient's blood purification treatment. Traditional technology requires setting a pressure warning range based on empirical values ​​when testing the pressure of the blood purification circuit. This setting method relies entirely on manual setting, which can easily set the pressure warning range too wide or too narrow. Since each patient's physical condition is different, the criteria for judging pressure failure during blood purification will also be different.

[0003] Therefore, the traditional manual setting method cannot provide a reasonable pressure warning range, and the judgment error is large; it cannot meet the accuracy requirements of pressure fault judgment for different patients, and the scope of application is limited. Summary of the Invention

[0004] Based on this, the present application provides a blood purification device and storage medium, which can provide a more reasonable and scientific judgment standard for pressure failure, reduce judgment errors, and ensure the safe operation of the blood purification device.

[0005] In a first aspect, the present application provides a blood purification device, comprising: a blood circuit and a blood purifier, wherein the blood circuit is used to transmit liquid, the blood purifier is connected in series in the blood circuit, and the blood purifier is used to purify blood; the blood purification device also comprises: a memory and a processor, wherein the memory is used to store a computer program; the processor is used to execute the computer program and, when executing the computer program, implement the following blood purification device pressure fault detection method:

[0006] When it is detected that the continuous purification time of the blood purifier is equal to a first preset time, the pressure of the blood circuit is detected to obtain a standard pressure value;

[0007] determining a pressure alarm range of the blood circuit according to the standard pressure value;

[0008] When it is detected that the continuous purification time of the blood purifier is greater than the first preset time, detecting the pressure of the blood circuit to obtain a pressure detection value;

[0009] It is determined whether a pressure failure occurs in the blood circuit based on the pressure detection value and the pressure alarm range.

[0010] In a second aspect, the present application provides a computer-readable storage medium storing a computer program, which, when executed by a processor, enables the processor to implement the pressure fault detection method for the blood purification device as described above.

[0011] An embodiment of the present application provides a blood purification device and a storage medium. When the continuous purification time of the blood purifier is equal to a first preset time, it indicates that the purification process of the blood purifier is in a stable state and the pressure of the blood circuit is also in a stable state. At this time, the pressure obtained by detecting the blood circuit is used as the standard pressure value. The standard pressure value obtained in this way can more accurately reflect the standard value of the blood circuit during the blood purification process, and can accurately determine whether a pressure fault occurs in the blood circuit based on the standard pressure value; therefore, the embodiment of the present application sets the judgment standard for pressure fault according to the pressure value of the blood circuit itself, which can make the judgment standard for pressure fault more reasonable and scientific, reduce the error in judging the pressure fault of the blood circuit, and ensure the safe operation of the blood purification device.

[0012] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a structural diagram of an embodiment of the blood purification device of the present application;

[0014] Figure 2 This is a schematic diagram of the working principle of an embodiment of the blood purification device of the present application;

[0015] Figure 3 This is a flow chart of an embodiment of a method for detecting a pressure failure of a blood purification device according to the present application;

[0016] Figure 4 This is a diagram showing the relationship between the liquid flow rate of the pipeline and the pressure fluctuation range of the pipeline in the pressure fault detection method of the blood purification equipment of the present application;

[0017] Figure 5 It is a structural schematic diagram of another embodiment of the blood purification device of the present application. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0019] The flowcharts shown in the accompanying drawings are for illustrative purposes only and do not necessarily include all contents and operations / steps, nor must they be executed in the order described. For example, some operations / steps may be decomposed, combined, or partially merged, so the actual execution order may vary depending on the actual situation.

[0020] Before describing the embodiments of the present application in detail, the relevant technical contents are first introduced.

[0021] Blood purification equipment is a device that draws blood out of the patient's body and purifies it to remove certain pathogenic substances and purify the blood to achieve the purpose of treating diseases. Taking the Continuous Renal Replacement Therapy (CRRT) machine as an example, the CRRT machine can achieve blood purification treatments such as dialysis / filtration, perfusion, and ultrafiltration. Figure 1 The diagram shows the structure of a CRRT machine. With the continuous development of blood purification technology, CRRT has expanded from treating acute and chronic renal failure to rescuing and treating patients with acute and critical illnesses such as multiple organ dysfunction syndrome, systemic inflammatory response syndrome, fulminant liver failure, and severe hemorrhagic necrotizing pancreatitis. Clinical practice has proven that CRRT machines have achieved excellent blood purification treatment results.

[0022] During CRRT blood purification therapy, various blood purification parameters (such as blood purification circuit pressure) need to be monitored to monitor the patient's blood purification safety. Traditionally, blood purification circuit pressure monitoring requires setting a pressure warning range based on empirical values. For example, the pressure warning range is -300 mmHg to 400 mmHg. This setting method relies entirely on manual setting, making it very easy to set the pressure warning range too wide or too narrow. If the pressure warning range is set too wide, blood purification circuit pressure alarms may be missed (i.e., an alarm is not triggered when it should be). If the pressure warning range is set too narrow, false blood purification circuit pressure alarms may occur (i.e., an alarm is triggered when it should not be). Furthermore, due to the individual patient's individual constitution, the criteria for determining blood purification circuit pressure failures may also vary. For example, some patients experience higher blood purification circuit pressures during blood purification therapy, while others experience lower pressures.

[0023] Therefore, the traditional manual setting method cannot provide a reasonable pressure warning range, and the pressure fault judgment error of the blood purification pipeline is large; it cannot meet the accuracy requirements of pressure fault judgment of different patients, and the scope of application is limited.

[0024] In the embodiment of the present application, when the continuous purification time of the blood purifier is equal to the first preset time, it means that the purification process of the blood purifier is in a stable state and the pressure of the blood circuit is also in a stable state. At this time, the pressure obtained by detecting the blood circuit is used as the standard pressure value. The standard pressure value obtained in this way can more accurately reflect the standard value of the blood circuit during the blood purification process, and can accurately determine whether a pressure fault occurs in the blood circuit based on the standard pressure value; therefore, the embodiment of the present application sets the judgment standard for pressure fault according to the pressure value of the blood circuit itself, which can make the judgment standard for pressure fault more reasonable and scientific, reduce the error in judging the pressure fault of the blood circuit, and ensure the safe operation of the blood purification equipment.

[0025] In order to better illustrate the embodiments of this application, Figure 2 The working principle diagram of the CRRT machine is shown (the CRRT machine is a blood purification device), as shown in FIG. Figure 2 As shown, the blood purification equipment includes: a blood circuit and a blood purifier. The blood circuit is used to transmit liquids, and the blood purifier is connected in series in the blood circuit. The blood purifier is used to purify blood. According to the function of the blood circuit pipeline, the blood circuit can be divided into: arterial pipeline, venous pipeline, anticoagulant pipeline, etc. The arterial pipeline is connected between the patient's artery and the blood input end of the blood purifier. The arterial pipeline outputs the patient's blood to the blood input end of the blood purifier; the venous pipeline is connected between the patient's vein and the blood output end of the blood purifier. The venous pipeline returns the purified blood to the patient's vein; the anticoagulant pipeline is connected to the arterial pipeline. The anticoagulant pipeline is used to output the anticoagulant to the arterial pipeline. The anticoagulant has a blood anticoagulant effect in the blood purifier and the blood circuit to ensure the safety of blood flow.

[0026] Figure 2 The schematic diagram shown is the most basic working principle diagram of the CRRT machine. When the CRRT machine is used in different blood purification treatment modes, the working principle diagram of the CRRT machine will be Figure 2 Under different blood purification treatment modes, the type of blood purifier will be different. For example, in the blood perfusion treatment mode, the blood purifier is a blood perfusion device; for example, in the hemodialysis treatment mode, the blood purifier is a dialyzer; and so on.

[0027] like Figure 2As shown, as fluid flows through the blood circuit, its pressure changes. For example, arterial pressure represents the pressure of fluid within the arterial line, and this pressure can be used to determine whether the arterial line is clogged. Similarly, venous pressure represents the pressure of fluid within the venous line, and this pressure can be used to determine whether the line is clogged or coagulated. Therefore, blood circuit pressure is of great reference value and is one of the most important parameters for determining the safety of blood purification treatment.

[0028] See also Figure 3 , Figure 3 This is a flow chart of an embodiment of a method for detecting pressure failures in a blood purification device according to the present application. It should be noted that the method according to the embodiment of the present application is performed by a blood purification device. The blood purification device comprises a blood circuit and a blood purifier, wherein the blood circuit is used to transmit liquids, and the blood purifier is connected in series with the blood circuit and is used to purify blood.

[0029] The method includes: step S101, step S102, step S103 and step S104.

[0030] Step S101: When it is detected that the continuous purification time of the blood purifier is equal to a first preset time, the pressure of the blood circuit is detected to obtain a standard pressure value.

[0031] When the blood purification device receives a start-up operation from the user, it generates a start-up instruction and controls the blood purifier to purify the blood according to the start-up instruction. Specifically, the blood purification device starts to start according to the start-up instruction, the blood purifier is connected to the blood, and the blood purifier starts to purify the blood.

[0032] The continuous purification time of the blood purifier is calculated with the time point when the blood purifier starts purification as the time starting point. When the blood purifier starts purification, it will go through the startup state, stable state, etc. In the startup state, blood will be introduced into the blood circuit (including arterial line, venous line, etc.), and the pressure of the blood circuit will change rapidly (usually rise rapidly). When the blood purification reaches the stable state, the blood flow rate in the blood circuit is maintained at a certain relatively stable level, and the pressure of the blood circuit will also be in a relatively stable state.

[0033] In the embodiment of the present application, the first preset time may refer to the critical time point between the start-up state and the stable state. When the continuous purification time of the blood purifier is equal to the first preset time, the blood purification stage of the blood purifier will jump from the start-up state to the stable state. At the first preset time, the pressure of the blood circuit detected is the pressure of the blood circuit in the stable state, and the pressure of the blood circuit in the stable state is used as the standard pressure value. Therefore, the standard pressure value can represent the baseline value of the blood circuit pressure of the patient during normal blood purification.

[0034] It should be noted that in the startup state, the blood circuit pressure is not representative and cannot accurately reflect the actual pressure standard of the patient's pipeline during blood purification treatment. Therefore, the standard pressure value is only obtained when the blood purifier's continuous purification time equals the first preset time. This can eliminate the interference of the blood circuit pressure fluctuation value during the startup state on the standard pressure value.

[0035] It should be noted that the pressure of the blood circuit may refer to the pressure of the liquid in the blood circuit, wherein the liquid in the blood circuit may refer to blood or anticoagulant, etc. Figure 2 As shown, the liquid in the arterial line is blood, and the liquid in the anticoagulant line is anticoagulant.

[0036] Step S102: determining a pressure alarm range of the blood circuit according to the standard pressure value.

[0037] There are many ways to determine the pressure alarm range of the blood circuit according to the standard pressure value. A common way is to determine the pressure alarm range of the blood circuit according to the standard pressure value and a preset pressure alarm span.

[0038] The pressure alarm span can represent the normal fluctuation range of the blood circuit pressure. When the blood purifier is in a stable state, the pressure of the blood circuit will fluctuate around the standard pressure value. The pressure alarm span can limit the fluctuation standard of the blood circuit pressure under normal circumstances.

[0039] Specifically, with the standard pressure value as the center value, the difference between the maximum and minimum values ​​in the pressure alarm range is exactly equal to the pressure alarm span. For example, if the standard pressure value is 100 mmHg and the pressure alarm span is 100 mmHg, then the blood circuit pressure alarm range can be 50 mmHg to 150 mmHg. Under stable conditions, if the blood circuit pressure is within the range of 50 mmHg to 150 mmHg, the blood circuit pressure is normal; if the blood circuit pressure is not within the range of 50 mmHg to 150 mmHg, the blood circuit pressure is abnormal. This example is merely an illustration of the pressure alarm range and does not constitute a technical limitation.

[0040] Step S103: When it is detected that the continuous purification time of the blood purifier is greater than the first preset time, the pressure of the blood circuit is detected to obtain a pressure detection value.

[0041] Step S104: determining whether a pressure failure occurs in the blood circuit based on the pressure detection value and the pressure alarm range.

[0042] Wherein, step S104, determining whether a pressure fault occurs in the blood circuit based on the pressure detection value and the pressure alarm range, may include: when the pressure detection value is not within the pressure alarm range, determining that a pressure fault occurs in the blood circuit and issuing a pressure alarm signal.

[0043] When the blood purifier is in a stable state, the blood circuit pressure detection value is detected to determine whether the blood circuit pressure has failed, and the safety of the liquid flow in the blood circuit is monitored. For example, the blood circuit pressure alarm range is: 50mmHg ~ 150mmHg. If the pressure detection value is 100mmHg, then 100mmHg is within 50mmHg ~ 150mmHg, the blood circuit pressure has not failed, and no pressure alarm signal is issued; if the pressure detection value is 200mmHg, then 200mmHg is not within 50mmHg ~ 150mmHg, the blood circuit pressure has failed, and a pressure alarm signal is issued. The pressure alarm signal is used to indicate that the blood circuit pressure is too high (the cause of the blood circuit pressure being too high is usually: the blood circuit is blocked), so that the user can promptly handle the blood circuit pressure failure to eliminate the blood circuit failure state.

[0044] It should be noted that the pressure alarm signal may be an audible or visual alarm signal. When it is detected that the pressure detection value is not within the pressure alarm range, an audible alarm or a light source alarm may be issued to serve as an alarm prompt.

[0045] In one embodiment, before step S102, determining the pressure alarm range of the blood circuit according to the standard pressure value and the preset pressure alarm span, the method may further include: step S105.

[0046] Step S105: setting a pressure alarm span of the blood circuit according to the detected liquid flow rate of the blood circuit.

[0047] Specifically, the liquid flow rate of the blood circuit is detected by an ultrasonic sensor. For example, the liquid flow rate of the blood circuit is 30 ml / min.

[0048] Specifically, there is a correlation between the liquid flow rate of the pipeline and the pressure of the pipeline. According to multiple technical test evidences, the greater the liquid flow rate of the pipeline, the greater the pressure fluctuation range of the pipeline. For example, Figure 4 The corresponding curve between the liquid flow rate of the pipeline and the pressure fluctuation range of the pipeline is shown; it should be noted that, Figure 4 The corresponding curves in the figure are obtained by summarizing multiple technical tests. Figure 4 The source of the curves in the figure is not explained in detail.

[0049] In the embodiment of the present application, after obtaining the liquid flow of the blood circuit, the Figure 4 The corresponding curve in the figure is used to find the corresponding pressure alarm span, where the liquid flow rate of the blood circuit can be equivalent to Figure 4 The value of the horizontal axis, the pressure alarm span of the blood circuit can be equivalent to Figure 4 The value of the vertical axis in the middle. Therefore, the pressure alarm span set in this embodiment of the application is consistent with the liquid flow rate in the blood circuit. Based on the pressure alarm range, it is possible to accurately determine whether a blood circuit pressure failure has occurred, eliminating errors caused by changes in the liquid flow rate in the blood circuit in determining a blood circuit pressure failure.

[0050] In one embodiment, step S105, setting the pressure alarm span of the blood circuit according to the detected liquid flow rate of the blood circuit, may include: if the liquid flow rate of the blood circuit is greater than a minimum limit flow rate, setting the pressure alarm span of the blood circuit according to the detected liquid flow rate of the blood circuit.

[0051] At this time, the method further includes: step S106.

[0052] Step S106: If the liquid flow rate of the blood circuit is less than or equal to the minimum limit flow rate, a blockage fault prompt message is issued.

[0053] The minimum limit flow rate can be used as a boundary to determine whether the liquid in the blood circuit is flowing normally. For example, the minimum limit flow rate is 0.5 ml / min. Only when the liquid flow rate of the blood circuit is greater than the minimum limit flow rate, it is indicated that the liquid in the blood circuit is in a normal flow state. At this time, the pressure alarm span of the blood circuit is set according to the detected liquid flow rate of the blood circuit. When the liquid flow rate of the blood circuit is less than or equal to the minimum limit flow rate, it is indicated that the liquid in the blood circuit is in a blocked state. At this time, a blockage fault prompt message is issued. The blockage fault prompt message can remind the user that the liquid in the blood circuit is in an abnormal flow state, and the user should deal with the abnormal flow state of the blood circuit in time. Therefore, the embodiment of the present application can detect the blockage problem of the blood circuit in advance based on the minimum limit flow rate, thereby improving the detection efficiency and accuracy of liquid flow failures in the blood circuit.

[0054] In one embodiment, the method further includes: step S107 and step S108.

[0055] Step S107: When the pressure detection value is not within the pressure alarm range, the pressure detection value is stored and displayed.

[0056] Step S108: calibrating the pressure alarm span according to the pressure detection value.

[0057] Specifically, such as Figure 1 As shown, the blood purification device also includes: a display screen, wherein the display screen has an information display function and a command input function. When the pressure detection value is not within the pressure alarm range, the pressure detection value is stored and displayed. The user can view the pressure detection value on the display screen so that the user can promptly understand the pressure fault status of the blood circuit; and the embodiment of the present application can also store the pressure detection value of the blood circuit at any time to facilitate data query.

[0058] When a pressure alarm signal is issued, it indicates that there is a pressure failure in the blood circuit. The pressure detection value is used as an empirical value to calibrate the pressure alarm span so that the calibrated pressure alarm span can more accurately reflect the normal pressure range of the blood circuit, reducing false alarms or missed alarms of the blood circuit pressure.

[0059] For example, when a pressure alarm signal is issued, if, based on manual judgment, the pressure detection value at that time is clearly within the normal range, it is indicated that the pressure alarm span is set too narrow, causing a false alarm. The pressure alarm span is then calibrated. Specifically, the calibration method may be to increase the pressure alarm span so that the increased pressure alarm range covers the pressure detection value. Of course, this is only a basic calibration method. Embodiments of the present application may also employ other calibration methods, such as using intelligent algorithms (e.g., neural networks, genetic algorithms, etc.) to calibrate the pressure alarm span.

[0060] In one embodiment, step S101, when it is detected that the continuous purification time of the blood purifier is equal to a first preset time, detecting the pressure of the blood circuit to obtain a standard pressure value, may include: when it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the pipeline section of the blood circuit, detecting the pressure of the pipeline section of the blood circuit to obtain the standard pressure value of the pipeline section of the blood circuit, wherein the blood circuit is divided into different pipeline sections according to pipeline functions, and each pipeline section has a detection time corresponding to the pipeline section.

[0061] In an embodiment of the present application, the blood circuit is divided into different pipeline sections according to the functions of the pipelines in the blood circuit. A detection time corresponding to the pipeline sections of the blood circuit can be set according to the pipeline sections.

[0062] For details, see Figure 2 The blood circuit segments can include: arterial lines, venous lines, and anticoagulant lines. Each segment has a specific fluid transport function. During blood purification treatment, each segment can also exhibit corresponding pressure fluctuation characteristics.

[0063] The embodiment of the present application sets a corresponding detection time for each pipeline section, for example, the detection time for the arterial pipeline is: 3 minutes, the detection time for the venous pipeline is: 4 minutes, and the detection time for the anticoagulation pipeline is: 5 minutes. In combination with the above, the "detection time corresponding to each pipeline section" here is equivalent to the "first preset time for each pipeline section". When the continuous purification time of the blood purifier is equal to 3 minutes, the liquid flow in the arterial pipeline reaches a stable state. The pressure of the arterial pipeline detected at this time is used as the standard pressure value of the arterial pipeline, and the pressure alarm span of the arterial pipeline is set. The pressure alarm range of the arterial pipeline is set according to the standard pressure value of the arterial pipeline and the pressure alarm span of the arterial pipeline; when it is detected that the continuous purification time of the blood purifier is greater than 3 minutes, the pressure of the arterial pipeline is detected to obtain the pressure detection value of the arterial pipeline; whether the pressure detection value of the arterial pipeline is within the pressure alarm range of the arterial pipeline is detected. When it is detected that the pressure detection value of the arterial pipeline is not within the pressure alarm range of the arterial pipeline, a pressure alarm signal is issued, and the pressure alarm signal indicates that there is a fault in the pressure of the arterial pipeline.

[0064] In the embodiment of the present application, the blood circuit is divided into different pipeline segments, and a corresponding standard pressure value is set for each pipeline segment. The standard pressure value of each pipeline segment can more accurately reflect the baseline state of the pressure within each pipeline segment. Therefore, based on the standard pressure value within each pipeline segment, it is possible to accurately determine whether the pressure of the pipeline segment of the blood circuit has a fault, thereby making the standard pressure value more accurate.

[0065] In one embodiment, step S101, when it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the pipeline section of the blood circuit, the pressure of the pipeline section of the blood circuit is detected to obtain the standard pressure value of the pipeline section of the blood circuit, can also include: sub-step S1011 and sub-step S1012.

[0066] Sub-step S1011: When it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the first pipeline section of the blood circuit, a pressure sensor is used to detect the pressure of the first pipeline section of the blood circuit to obtain a standard pressure value of the first pipeline section of the blood circuit, wherein the length of the first pipeline section of the blood circuit is less than or equal to the preset pipeline length, and the first pipeline section is provided with a pressure detection point, and a pressure sensor is provided on the pressure detection point.

[0067] Sub-step S1012: When it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the second pipeline section of the blood circuit, at least two pressure sensors are used to detect the pressure of the second pipeline section of the blood circuit, and the average value of the pressures detected by the at least two pressure sensors is used as the standard pressure value of the second pipeline section of the blood circuit, wherein the length of the second pipeline section of the blood circuit is greater than the preset pipeline length, and at least two pressure detection points are set on the second pipeline section, and each of the pressure detection points is provided with a pressure sensor.

[0068] Specifically, during the blood purification process of the blood purification device, different pipeline sections in the blood circuit usually have different lengths. For example, the length of the arterial pipeline is usually longer than the length of the anticoagulation pipeline, and the length of the venous pipeline is usually longer than the length of the arterial pipeline. Therefore, in order to more accurately obtain the standard pressure value of the pipeline section, the embodiment of the present application sets the pressure detection method of the pipeline section according to the length of the pipeline section. When the length of the second pipeline section of the blood circuit is greater than the preset pipeline length, at least two pressure detection points are set on the second pipeline section, and each pressure detection point is set at a pressure sensor. When the length of the first pipeline section of the blood circuit is less than or equal to the preset pipeline length, the first pipeline section is set at a pressure detection point, and the pressure detection point is set at a pressure sensor. For example, if the preset pipeline length is 0.6m, when the length of the second pipeline section of the blood circuit is greater than 0.6m, at least two pressure sensors need to be set on the second pipeline section of the blood circuit to obtain the standard pressure value of the second pipeline section in the form of an average pressure value to avoid the problem of large error in setting the standard pressure value due to the length of the second pipeline section being too long.

[0069] For example, if the length of the venous line is 0.7m, 0.7m>0.6m, then it is necessary to select two pressure detection points on the venous line and set a pressure sensor at each pressure detection point, such as Figure 2 As shown, a pressure sensor is set on the inlet side of the venous line (that is, close to the blood output end of the blood purifier), and another pressure sensor is set on the outlet side of the venous line (that is, close to the human vein end). When it is detected that the continuous purification time of the blood purifier is equal to the corresponding detection time of the venous line, the pressure sensor is used to detect the pressure of the venous line, and the average value of the pressures detected by the two pressure sensors is used as the standard pressure value of the venous line; for example, the pressures detected by the two pressure sensors are: 100mmHg and 150mmHg respectively, then the average value is: (100+150) / 2mmHg=125mmHg, and the standard pressure value of the venous line is: 125mmHg.

[0070] If the length of the anticoagulation line is 0.3m, and 0.3m<0.6m, it is necessary to select a pressure detection point on the anticoagulation line and set a pressure sensor at the pressure detection point, such as Figure 2 As shown, a pressure sensor is set at the midpoint of the anticoagulation pipeline. When it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the anticoagulation pipeline, the pressure of the anticoagulation pipeline is detected by the pressure sensor, and the detected pressure of the anticoagulation pipeline is used as the standard pressure value of the anticoagulation pipeline; for example, if the pressure detected by the pressure sensor is: 100mmHg, then the standard pressure value of the anticoagulation pipeline is: 100mmHg.

[0071] The embodiment of the present application distinguishes the lengths of the pipeline sections of the blood circuit so as to respectively set different numbers of pressure sensors on the pipeline sections, thereby improving the setting accuracy of the standard pressure value.

[0072] It should be noted that the above-mentioned preset pipeline length can be obtained through multiple technical experiments, and the specific numerical setting method of the preset pipeline length is not described in detail here.

[0073] It should be noted that the number and location of pressure monitoring points within a blood circuit segment can be selected based on operational experience. For example, if two pressure monitoring points are required, they are typically located at the inlet and outlet of the segment. Alternatively, if three pressure monitoring points are required, they are typically located at the inlet, outlet, and midpoint of the segment. By selecting a reasonable number of pressure monitoring points within a blood circuit segment, pressure changes within the segment can be accurately detected. The specific number and location of pressure monitoring points will not be described in detail.

[0074] In one embodiment, step S104, issuing a pressure alarm signal when the pressure detection value is not within the pressure alarm range, may include: sub-step S1041 and sub-step S1042.

[0075] Sub-step S1041: When the pressure detection value is not within the pressure alarm range, determining the pressure alarm level of the blood circuit according to the absolute value of the difference between the pressure detection value and the standard pressure value.

[0076] Sub-step S1042: issuing pressure alarm information corresponding to the pressure alarm level of the blood circuit.

[0077] Specifically, the embodiment of the present application issues different pressure alarm information based on the absolute value of the difference between the pressure detection value and the standard pressure value. The user can distinguish the pressure alarm level of the blood circuit based on the pressure alarm information, and the user can promptly deal with fault conditions with higher pressure alarm levels, thereby ensuring the safety of liquid flow in the blood circuit and bringing greater operational convenience to the blood purification process.

[0078] In one embodiment, in sub-step S1041 , determining the pressure alarm level of the blood circuit according to the absolute value of the difference between the pressure detection value and the standard pressure value may include: sub-step S1041A and sub-step S1041B.

[0079] Sub-step S1041A: If the absolute value of the difference between the pressure detection value and the standard pressure value is greater than the pressure alarm span, determining that the pressure alarm level of the blood circuit is the first priority.

[0080] Sub-step S1041B: If the absolute value of the difference between the pressure detection value and the standard pressure value is less than or equal to the pressure alarm span, determining that the pressure alarm level of the blood circuit is the second priority.

[0081] For example, the pressure alarm span is 100mmHg, the standard pressure value is 100mmHg, and the pressure alarm range of the blood circuit is 50mmHg to 150mmHg; when the pressure detection value of the blood circuit is 160mmHg, the pressure detection value is not within the pressure alarm range, and the difference between the pressure detection value and the standard pressure value is (160-100)mmHg=60mmHg, 60mmHg<100mmHg, then the pressure alarm level of the blood circuit is classified as the second priority, and the pressure alarm information under the second priority is: emit green light to serve as a fault prompt function; when the blood circuit pressure detection value ... If the pressure detection value of the blood circuit is: 210mmHg, the pressure detection value is not within the pressure alarm range, and the difference between the pressure detection value and the standard pressure value is: (210-100)mmHg=110mmHg. At this time, the pressure alarm level of the blood circuit is classified as the first priority. The pressure alarm information under the first priority is: emitting a red light; the fault urgency under the first priority is greater than the fault urgency under the second priority. Therefore, the user can accurately distinguish the pressure alarm level of the blood circuit based on the pressure alarm information, which is convenient for timely handling of the pressure fault state of the blood circuit and ensuring the safety of liquid flow in the blood circuit.

[0082] When the absolute value of the difference between the pressure detection value and the standard pressure value is greater than the pressure alarm span, it means that the pressure detection value of the blood circuit is too large. This fault state will seriously endanger the patient's blood purification treatment safety. The pressure alarm level is divided into the first priority level to eliminate the pressure fault state of the blood circuit as soon as possible; when the absolute value of the difference between the pressure detection value and the standard pressure value is less than or equal to the pressure alarm span, it means that although the pressure detection value of the blood circuit is not within the pressure alarm range, this fault state will not immediately endanger the patient's blood purification treatment safety. However, if the patient is in this fault state for a long time, it will damage the patient's blood purification treatment safety. The pressure alarm level is divided into the second priority level. In the embodiment of the present application, there is a one-to-one correspondence between each pressure alarm level and each pressure alarm information. According to the pressure alarm information, the pressure alarm level of the blood circuit can be accurately distinguished, which brings greater convenience to the blood purification treatment control process of the blood purification equipment.

[0083] In one embodiment, the method further includes: step S109.

[0084] Step S109: When the continuous purification time of the blood purifier meets the first condition, the pressure of the blood circuit is detected to obtain an updated standard pressure value. The first condition is: the difference between the continuous purification time of the blood purifier and the first preset time divided by the preset pressure update period is equal to n, and n is any positive integer.

[0085] Expressed mathematically, the first condition is: (continuous purification time of the blood purifier - first preset time) / pressure update period = n, where n is any positive integer.

[0086] Specifically, when the continuous purification time of the blood purifier is greater than the first preset time, the standard pressure value of the blood circuit needs to be updated in real time to adapt to the pressure changes in the blood circuit; the updated pressure alarm range is set according to the pressure alarm span of the blood circuit and the updated standard pressure value. Based on the updated pressure alarm range, it is possible to more accurately judge whether the pressure of the blood circuit has a fault, thereby improving the accuracy of blood circuit pressure fault judgment.

[0087] Exemplarily, the pressure update cycle of the blood circuit is 10 minutes, and the first preset time is 5 minutes. When the continuous purification time of the blood purifier is equal to 5 minutes, the pressure of the blood circuit is detected to be 100 mmHg, and the standard pressure value is 100 mmHg at this time; when it is detected that the continuous purification time of the blood purifier is greater than 5 minutes, it is determined whether there is a pressure failure in the blood circuit based on the pressure detection value of the blood circuit; when the continuous purification time of the blood purifier reaches 15 minutes, then (continuous purification time of the blood purifier-first preset time) / pressure update cycle = (15-5) / 10 = 1, which meets the first condition, and the pressure of the blood circuit is detected as the updated standard pressure value. For example, the detected pressure of the blood circuit is: 90 mmHg, then the updated standard pressure value is: 90 mmHg; and so on, according to the first condition, when the continuous purification time of the blood purifier reaches: 25 minutes, 35 minutes, 45 minutes, 55 minutes...; the pressure of the blood circuit is detected to update the standard pressure value of the blood circuit. Therefore, the embodiment of the present application can adaptively update the standard pressure value during the blood purification treatment process, reducing the pressure fault judgment error caused by the standard pressure value setting process.

[0088] In one embodiment, the method further includes: step S110.

[0089] Step S110: Determine the pressure update period according to the pressure alarm span of the blood circuit.

[0090] Specifically, there is a correlation between the pressure update cycle and the pressure alarm span. Generally, the larger the pressure alarm span, the longer the blood circuit pressure update cycle. This is because once the pressure alarm span is set very large, the standard pressure value has less influence on the accuracy of blood circuit fault diagnosis, and the standard pressure value does not need to be updated too frequently. In actual applications, there are many ways to set the blood circuit pressure update cycle based on the blood circuit pressure alarm span. For example, a corresponding table (such as Table 1 below) can be pre-set, and the blood circuit pressure update cycle can be set according to the corresponding relationship in the corresponding table. For example, when the blood circuit pressure alarm span is obtained as 100 mmHg, according to the corresponding relationship in Table 1, the blood circuit pressure update cycle is 10 minutes. Therefore, the embodiment of the present application can adaptively set the blood circuit pressure update cycle to improve the setting accuracy and update efficiency of the standard pressure value.

[0091] Table 1

[0092]

[0093]

[0094] It should be noted that the corresponding relationship in Table 1 is obtained based on multiple technical experiments, and no detailed description of the corresponding relationship in Table 1 is given here.

[0095] In one embodiment, the method further includes: step S111.

[0096] Step S111: when the pressure detection value is within the pressure alarm range and the absolute value of the difference between the pressure detection value and the standard pressure value is greater than a preset pressure value, calibrating the standard pressure value according to the pressure detection value.

[0097] Specifically, when the pressure detection value of the blood circuit is within the pressure alarm range, it indicates that there is no pressure failure in the blood circuit; the above-mentioned preset pressure value is used to evaluate the degree to which the pressure of the blood circuit deviates from the standard pressure value; when the absolute value of the difference between the pressure detection value and the standard pressure value is greater than the preset pressure value, it indicates that the degree to which the pressure detection value deviates from the standard pressure value of the blood circuit is too large. If it is determined that there is no pressure failure in the blood circuit, then the standard pressure value set in this case is unreasonable, and the standard pressure value needs to be calibrated according to the pressure detection value. The calibrated standard pressure value is increased or decreased to reduce the error in judging the pressure failure of the blood circuit.

[0098] For example, the pressure alarm range of the blood circuit is: 50mmHg~150mmHg, the standard pressure value is 100mmHg, and the preset pressure value is: 30mmHg; if the pressure detection value is 120mmHg, then (120-100)mmHg=20mmHg<30mmHg, then there is no need to calibrate the standard pressure value of the blood circuit according to the pressure detection value; if the pressure detection value is 135mmHg, then (135-100)mmHg=35mmHg>30mmHg, although the pressure detection value is in the pressure alarm range range, but the absolute value of the difference between the pressure detection value and the standard pressure value is obviously too large (greater than the preset pressure value). This difference indicates that the standard pressure value is likely to be set unreasonably, and the standard pressure value of the blood circuit needs to be calibrated according to the pressure detection value. For example, the standard pressure value can be increased. The increased standard pressure value is: 105 mmHg, and the updated pressure alarm range of the blood circuit is: 55 mmHg ~ 155 mmHg; therefore, according to the updated pressure alarm range, it is possible to more accurately identify whether there is a pressure fault in the blood circuit.

[0099] It should be noted that the above embodiment can calibrate the pressure detection value in a variety of ways, such as calibration through a neural network algorithm in traditional technology, etc.

[0100] In one embodiment, the method further includes: step S112, step S113 and step S114.

[0101] Step S112: When the continuous purification time of the blood purifier is equal to the first preset time, the temperature of the liquid in the blood circuit is detected to obtain a standard temperature.

[0102] Step S113: When the continuous purification time of the blood purifier is greater than the first preset time, the temperature of the liquid in the blood circuit is detected to obtain a detected temperature.

[0103] Step S114: When the absolute value of the difference between the detected temperature and the standard temperature is greater than a first preset temperature and the pressure detection value is within the pressure alarm range, the currently detected pressure detection value is used as the updated standard pressure value. Simultaneously, the currently detected liquid temperature may also be used as the updated standard temperature.

[0104] Specifically, according to common knowledge related to liquid pressure, there is a correlation between the pressure in the blood circuit and the temperature of the liquid in the blood circuit. When the temperature of the liquid in the blood circuit changes, the pressure in the blood circuit will also change accordingly. For example, when other factors remain unchanged, when the temperature of the liquid in the blood circuit increases, the pressure in the blood circuit will also increase. In the embodiment of the present application, when detecting the standard pressure value of the blood circuit, the standard temperature in the blood circuit will be detected simultaneously. When the continuous purification time of the blood purifier is greater than the first preset time, when detecting the temperature of the liquid in the blood circuit, it is determined whether the temperature of the liquid in the blood circuit will affect the accuracy of the blood circuit pressure fault judgment. If the absolute value of the difference between the detected temperature of the liquid in the blood circuit and the standard temperature is greater than the first preset temperature, it means that the temperature of the liquid in the blood circuit has suddenly changed. This sudden change in the temperature of the liquid in the blood circuit has exceeded the preset temperature change range. The standard pressure value detected at the standard temperature can no longer accurately determine whether the pressure of the blood circuit has a fault. At this time, the pressure of the blood circuit is re-detected at the current liquid temperature as the updated standard pressure value, and the updated standard pressure value is used as the standard value of the normal pressure of the blood circuit. Therefore, the embodiment of the present application automatically updates the standard pressure value according to the temperature of the liquid in the blood circuit, and determines whether a pressure fault occurs in the blood circuit based on the updated pressure alarm range, thereby eliminating the interference error caused by the temperature change of the liquid in the blood circuit in the judgment of the pressure fault of the blood circuit. The embodiment of the present application has a higher judgment accuracy for the pressure fault of the blood circuit.

[0105] For example, the first preset time is: 5min. When it is detected that the continuous purification time of the blood purifier is equal to 5min, the temperature of the liquid in the blood circuit is detected to be: 35℃. The temperature at this time is used as the standard temperature. At the standard temperature of 35℃, the standard pressure value of the blood circuit is: 100mmHg. The pressure alarm range obtained according to the standard pressure value is: 50mmHg~150mmHg; if the continuous purification time of the blood purifier is equal to 15min, the temperature of the liquid in the blood circuit is detected to be: 39℃. If it is concluded based on multiple tests, : The first preset temperature is 3°C, |39°C-35°C|=4°C>3°C, which means: the temperature of the liquid in the blood circuit has changed suddenly. At 39°C, the standard pressure value of the blood circuit needs to be retested. For example, the retested standard pressure value is: 105mmHg, then the updated standard pressure value is 105mmHg, the updated pressure alarm range is: 55mmHg~155mmHg, and the updated standard temperature is 39°C; in the future blood purification treatment process, the updated pressure alarm range is used to determine whether there is a pressure failure in the blood circuit.

[0106] It should be noted that the first preset temperature can be obtained by summarizing multiple tests. When updating the standard pressure value, the embodiment of the present application also updates the standard temperature, and uses the currently detected temperature of the liquid in the blood circuit as the updated standard temperature.

[0107] See also Figure 5 , Figure 5 This is a structural diagram of another embodiment of the blood purification device of the present application, wherein the blood purification device comprises: a blood circuit 1 and a blood purifier 2, wherein the blood circuit 1 is used to transmit liquid, the blood purifier 2 is connected in series in the blood circuit 1, and the blood purifier 2 is used to purify blood; the blood purification device further comprises: a memory 200 and a processor 300, wherein the memory 200 is used to store a computer program; the processor 300 is used to execute the computer program and, when executing the computer program, implement the pressure fault detection method of the blood purification device as described above. For detailed description of the relevant content, please refer to the relevant content of the pressure fault detection method of the blood purification device mentioned above, which will not be repeated here.

[0108] The blood purification device further comprises a host 100, on which the blood circuit 1 and the blood purifier 2 are mounted. The memory 200 and the processor 300 are connected via a bus, and the memory 200 and the processor 300 can be arranged inside or outside the host 100.

[0109] The processor 300 may be a micro control unit, a central processing unit, a digital signal processor, or the like.

[0110] The memory 200 may be a Flash chip, a read-only memory, a magnetic disk, an optical disk, a USB flash drive, or a mobile hard disk, etc.

[0111] This application also provides a computer-readable storage medium storing a computer program that, when executed by a processor, causes the processor to implement any of the above-described pressure failure detection methods for blood purification equipment. For detailed descriptions of the relevant content, please refer to the relevant content of the pressure failure detection method for blood purification equipment described above, which will not be repeated here.

[0112] The computer-readable storage medium may be an internal storage unit of the blood purification device, such as a hard disk or memory. The computer-readable storage medium may also be an external storage device, such as a plug-in hard disk, smart memory card, secure digital card, flash memory card, etc.

[0113] It should be understood that the terms used in the present specification are only used to describe specific embodiments and are not intended to limit the present application.

[0114] It will also be understood that the term "and / or" used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0115] The above descriptions are merely specific embodiments of the present application, but the scope of protection of the present application is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in the present application, and such modifications or substitutions should be included within the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.

Claims

1. A blood purification device, characterized in that: The blood purification device includes: a blood circuit and a blood purifier, wherein the blood circuit is used to transmit liquid, and the blood purifier is connected in series in the blood circuit and is used to purify blood; the blood purification device also includes: a memory and a processor, wherein the memory is used to store a computer program; and the processor is used to execute the computer program and, when executing the computer program, implement the following blood purification device pressure fault detection method: When it is detected that the continuous purification time of the blood purifier is equal to a first preset time, the pressure of the blood circuit is detected to obtain a standard pressure value; determining a pressure alarm range of the blood circuit according to the standard pressure value; When it is detected that the continuous purification time of the blood purifier is greater than the first preset time, detecting the pressure of the blood circuit to obtain a pressure detection value; determining whether a pressure failure occurs in the blood circuit based on the pressure detection value and the pressure alarm range; The blood circuit is divided into different pipeline sections according to pipeline functions, and each pipeline section has a detection time corresponding to the pipeline section; when the processor executes the computer program, it implements the following pressure fault detection method for blood purification equipment: When it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the first pipeline section of the blood circuit, a pressure sensor is used to detect the pressure of the first pipeline section of the blood circuit to obtain a standard pressure value of the first pipeline section of the blood circuit, wherein the length of the first pipeline section of the blood circuit is less than or equal to a preset pipeline length, and the first pipeline section is provided with a pressure detection point, and a pressure sensor is provided at the pressure detection point; When it is detected that the continuous purification time of the blood purifier is equal to the detection time corresponding to the second pipeline section of the blood circuit, at least two pressure sensors are used to detect the pressure of the second pipeline section of the blood circuit, and the average value of the pressures detected by the at least two pressure sensors is used as the standard pressure value of the second pipeline section of the blood circuit, wherein the length of the second pipeline section of the blood circuit is greater than the preset pipeline length, and at least two pressure detection points are arranged on the second pipeline section, and each of the pressure detection points is provided with a pressure sensor.

2. The blood purification device according to claim 1, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: When the pressure detection value is not within the pressure alarm range, determining that a pressure failure occurs in the blood circuit and issuing a pressure alarm signal; and / or, The pressure alarm range of the blood circuit is determined according to the standard pressure value and a preset pressure alarm span.

3. The blood purification device according to claim 2, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: setting a pressure alarm span of the blood circuit according to the detected liquid flow rate of the blood circuit; and / or, When the pressure detection value is not within the pressure alarm range, storing and displaying the pressure detection value; The pressure alarm span is calibrated according to the pressure detection value.

4. The blood purification device according to claim 3, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: If the liquid flow rate of the blood circuit is greater than a minimum limit flow rate, setting a pressure alarm span of the blood circuit according to the detected liquid flow rate of the blood circuit; and / or, If the liquid flow rate of the blood circuit is less than or equal to the minimum limit flow rate, a blockage fault prompt message is issued.

5. The blood purification device according to claim 2, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: When the pressure detection value is not within the pressure alarm range, determining the pressure alarm level of the blood circuit according to the absolute value of the difference between the pressure detection value and the standard pressure value; A pressure alarm message corresponding to the pressure alarm level of the blood circuit is issued.

6. The blood purification device according to claim 5, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: If the absolute value of the difference between the pressure detection value and the standard pressure value is greater than the pressure alarm span, determining that the pressure alarm level of the blood circuit is the first priority; If the absolute value of the difference between the pressure detection value and the standard pressure value is less than or equal to the pressure alarm span, the pressure alarm level of the blood circuit is determined to be the second priority.

7. The blood purification device according to claim 1, characterized in that: When the processor executes the computer program, the processor implements the following pressure failure detection method for the blood purification device: When the continuous purification time of the blood purifier satisfies a first condition, the pressure of the blood circuit is detected to obtain an updated standard pressure value, wherein the first condition is that the difference between the continuous purification time of the blood purifier and the first preset time divided by a preset pressure update period is equal to n, where n is any positive integer; and / or, When the continuous purification time of the blood purifier is equal to the first preset time, detecting the temperature of the liquid in the blood circuit to obtain a standard temperature; When the continuous purification time of the blood purifier is greater than the first preset time, the temperature of the liquid in the blood circuit is detected to obtain a detected temperature; When the absolute value of the difference between the detected temperature and the standard temperature is greater than a first preset temperature and the pressure detection value is within the pressure alarm range, the pressure detection value obtained by the current detection is used as the updated standard pressure value; and / or, When the pressure detection value is within the pressure alarm range and the absolute value of the difference between the pressure detection value and the standard pressure value is greater than a preset pressure value, the standard pressure value is calibrated according to the pressure detection value.

8. A computer-readable storage medium, characterized in that The computer-readable storage medium stores a computer program, which, when executed by a processor, enables the processor to implement the pressure failure detection method for a blood purification device according to any one of claims 1 to 7.

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