An aortic prosthesis that prevents commissural regurgitation

Abstract

The present application relates to the field of medical devices, and specifically to an aortic prosthesis capable of preventing junctional reflux, comprising a stent for support and anchoring, a positioning member for positioning and clamping autologous valve leaflets, and a leak-proof mechanism, wherein the stent comprises a plurality of expandable diamond-shaped grids, and the leak-proof mechanism comprises a sealing membrane and a support rod, one end of the support rod is connected to the diamond-shaped grids between adjacent positioning members, and extends downward to form a filling portion convex to the outside of the stent, the other end of the support rod is free, and the sealing membrane is connected to the diamond-shaped grid; wherein, when the aortic prosthesis is installed in place, the filling portion is located at the junction of the autologous valve leaflets and abuts against the vascular tissue, so that the filling portion drives the other end of the support rod to tilt toward the outside of the stent with the connection point between the support rod and the diamond-shaped grid as a fulcrum, and the sealing membrane unfolds with the support rod and forms an anti-reflux pocket to prevent blood reflux.

Description

Technical Field

[0001] The present application relates to the field of medical devices, and in particular to an aortic prosthesis capable of preventing juncture reflux. Background Art

[0002] At present, aortic valve stents mainly include mechanically expandable stents, balloon-expandable stents and self-expanding stents. After the release of mechanically expandable stents and balloon-expandable stents, the open area of ​​the valve is small, it is impossible to accurately position, and the transvalvular pressure difference is large. Although the transvalvular pressure difference and conduction block of the self-expanding stent are small after release, the coaxiality is poor after release, and it is impossible to accurately position, which can easily cause problems such as paravalvular leakage and valve slippage. At present, most aortic valve stents are designed for patients with aortic valve stenosis. For patients with aortic valve regurgitation, how to improve the prevention of reflux while retaining the function of the native valve leaflets, reducing the amount of implants, and at the same time ensuring the reliable anchoring of the implanted prosthesis in the heart to avoid problems such as falling off, are all issues that need to be urgently solved in this field.

[0003] Patent US13 / 738376 discloses a valve prosthesis including one or more anti-universal joint leakage components connected to a stent. The anti-valvular leakage component can surround the stent and include a radially expandable control ring, which is connected to the unconnected edge of the flexible skirt, which extends the unconnected skirt outward away from the stent and abuts against the native heart valve to form a pocket around the open annular stent. The anti-valvular leakage component can surround the periphery of the stent and include a flexible skirt, which has opposite edges connected to the stent to form one or more closed compartments around the stent. Each compartment includes a one-way valve that allows blood to flow into the compartment but prevents blood from flowing out of the compartment. The anti-valvular leakage component can be at least one flap, which is connected to the inner surface of the stent and is formed of a flexible material that can be moved by blood flow. In this solution, the anti-valvular leakage component is used to achieve the purpose of leakage prevention. Although the anti-valvular leakage component is a flexible material and can be freely filled into the corresponding recess to achieve leakage prevention, the flexible material may adhere to the stent, resulting in the anti-valvular leakage component being unable to fully stretch, resulting in paravalvular leakage.

[0004] Patent CN201380074734.8 discloses a stent-valve for transcatheter implantation to replace a heart valve. The stent-valve can be compressed to a compressed state for delivery, and can be expanded to a working state for implantation. The stent-valve includes a stent, a plurality of leaflets for defining an artificial valve, an inner skirt, an outer skirt, and a paravalvular seal for sealing against surrounding tissue. In some embodiments, the paravalvular seal includes a material that swells upon contact with blood. In some embodiments, the seal includes a flap or pocket that can expand in response to the back pressure of blood and / or paravalvular regurgitation. In this patent solution, the paravalvular seal is partially located below the autologous valve ring and partially located above the autologous valve ring. When preventing leakage, it has a two-layer barrier effect, making its leakage prevention effect better. However, since the paravalvular seal is flexible, it may adhere to the stent when the stent is released, resulting in the paravalvular seal being unable to unfold and paravalvular leakage occurring.

[0005] In summary, the problems that urgently need to be solved in this field include: how to allow the seal that prevents paravalvular leakage to fully expand when the stent is released so that it can fill the gap or depression in time and effectively prevent valve regurgitation. Summary of the invention

[0006] In view of the above and other concepts, this application is proposed. The main purpose of this application is to overcome some problems and shortcomings of the prior art.

[0007] The technical solution adopted to solve the technical problem of the present invention is: an aortic prosthesis capable of preventing reflux at the junction is provided, comprising: a stent for supporting and anchoring, a positioning member for positioning and clamping autologous valve leaflets, and a leak-proof mechanism, wherein the stent comprises a plurality of expandable diamond-shaped grids, the leak-proof mechanism comprises a sealing membrane and a support rod, one end of the support rod is connected to the diamond-shaped grids between adjacent positioning members, and extends downward to form a filling portion convex to the outside of the stent, the other end of the support rod is free, and the sealing membrane is connected to the diamond-shaped grid; wherein, when the aortic prosthesis is installed in place, the filling portion is located at the junction of the autologous valve leaflets and abuts against the vascular tissue, so that the filling portion drives the other end of the support rod to tilt toward the outside of the stent with the connection point between the support rod and the diamond-shaped grid as a fulcrum, and the sealing membrane unfolds with the support rod and forms an anti-reflux pocket to prevent blood reflux.

[0008] As a further improvement of the present invention, the positioning member includes a positioning portion and a connecting portion, and the stent is provided with a plurality of connecting structures at the distal end, and a support rod is provided on the connecting structure, and one end of the support rod is connected to the connecting portion of the positioning member, and the other end of the support rod is connected to the connecting structure; when the valve prosthesis reaches the target position, the positioning portion of the positioning member is released, and the two ends of the stent are restricted, so that the proximal end of the support rod is propped up toward the outside of the stent relative to the distal end of the support rod, and drives the positioning portion of the positioning member to be propped up toward the outside of the stent.

[0009] As a further improvement of the present invention, the connecting structure is a grid-like structure, and the struts are arranged in the grid of the connecting structure, wherein one end of the struts is fixedly connected to the connecting structure, the other end of the struts is free, and the other end of the struts is bent or inclined toward the inside of the stent; the purpose of such a design is that the connecting portion of the positioning member is connected to the other end of the strut, so that in a natural state, the positioning portion of the positioning member can be tightly attached to the outside of the stent, thereby significantly improving the clamping force of the positioning member and enhancing the anchoring effect of the valve prosthesis.

[0010] As a further improvement of the present invention, in a natural state, the positioning portion of the positioning member is in close contact with the outside of the stent; the design of the support rod allows the positioning member to open to a larger angle toward the outside of the stent when capturing the leaflets, and at the same time, after capturing the leaflets, the positioning member can provide a strong clamping force so that the valve prosthesis can be stably anchored in the heart.

[0011] As a further improvement of the present invention, in a natural state, the filling portion and the support rod are provided with a certain angle, so that after the filling portion is squeezed, the other end of the support rod can be pried to swing toward the outside of the stent, so that the support rod is close to the blood vessel wall, and the sealing film unfolds with the swing of the support rod to form an anti-reflux pocket to prevent blood reflux.

[0012] As a further improvement of the present invention, the stent has an inflow end and an outflow end. When the aortic prosthesis is installed in place, the support rod and the sealing membrane are located at the outflow end of the stent, and the anti-reflux pocket is located at the junction of the native valve leaflets.

[0013] As a further improvement of the present invention, when the aortic prosthesis is installed in place, the filling portion drives the other end of the supporting rod to abut against the vascular tissue.

[0014] As a further improvement of the present invention, during preinstallation, the support rod enters the diamond grid, and the length of the support rod is less than or equal to the axial length of the diamond grid; the advantage of this design is that the support rod does not occupy the space of the delivery sheath during preinstallation, the diameter of the delivery sheath can be reduced, and it is convenient for transvascular access.

[0015] As a further improvement of the present invention, during pre-installation, the filling portion enters the gap between the adjacent diamond grids, and the free end of the filling portion does not extend axially to the outside of the stent; the advantage of such a design is that the filling portion does not occupy the space of the delivery sheath during pre-installation, which can reduce the diameter of the delivery sheath and facilitate transvascular access.

[0016] As a further improvement of the present invention, the other end of the support rod is provided with an attachment structure. When the aortic prosthesis is installed in place, the attachment structure of the support rod fits the blood vessel wall. The attachment structure is relatively flexible, so that the support rod can avoid puncturing the blood vessel tissue when it is attached to the blood vessel wall.

[0017] As a further improvement of the present invention, the connection point between the support rod and the diamond grid is located at the autologous valve ring, and when the aortic prosthesis is installed in place, the filling part is against the autologous valve ring tissue; and the filling part is located at the junction of the autologous valve leaflets. After the positioning parts clamp the valve leaflets, there is no autologous valve leaflets to block the junction, which makes it easier for regurgitation to occur. The filling part is against the autologous valve ring and is located at the junction of the autologous valve leaflets, which can drive the support rod and the sealing membrane to prevent leakage at the junction of the valve leaflets.

[0018] As a further improvement of the present invention, the sealing film is made of biological tissue or fabric or polymer material.

[0019] As a further improvement of the present invention, the free end of the filling part is bent, and the filling part is covered with a fabric layer with a buffering effect; the purpose of such a design is that the filling part can effectively avoid stabbing the tissue when it abuts against the tissue.

[0020] According to another embodiment, the free end of the filling portion is flat, and the free end of the filling portion can adaptively fit the autologous valve ring tissue located at the junction of the autologous valve leaflets. Furthermore, the free end of the filling portion is covered with fabric. The advantage of such a design is that the filling portion can further fill the space occupied by the autologous valve ring tissue at the junction of the autologous valve leaflets, and the anti-reflux pocket formed by the support rod and the sealing membrane can achieve double leakage protection for the junction of the valve leaflets.

[0021] Compared with the prior art, the advantages and beneficial technical effects of the present application include at least the following:

[0022] 1. In the prior art, although the aortic prosthesis can adaptively fill the gap or depression to prevent reflux, its anti-leakage device is made of flexible material, which means that after the stent is released, its anti-leakage device may be attached to the stent and cannot be unfolded, thereby causing reflux. Different from the prior art, after the positioning member clamps the native valve leaflets, the native valve leaflets can block the blood flow, but in the area where the native valve leaflets meet, the native valve leaflets cannot cover it, so reflux is prone to occur. An embodiment of the present application utilizes the filling part to use the connection point between the support rod and the stent grid as a fulcrum to pry the other end of the support rod toward the outside of the stent, so that the support rod drives the sealing film to form an anti-reflux pocket, and the anti-reflux pocket is located at the junction of the native valve leaflets, which can specifically make up for the area that the native valve leaflets cannot cover, and the reflux effect is significant. In addition, the support rod is located in the grid of the stent, and will not occupy the space of the delivery sheath during pre-installation, which is conducive to delivery via vascular access and has good clinical significance.

[0023] 2. Different from the prior art, in one embodiment of the present application, the filling portion is squeezed to drive the support rod to tilt up, and the support rod cooperates with the sealing film to form an anti-reflux pocket, which can ensure that the anti-reflux structure can be deployed to prevent blood reflux and avoid the sealing film being attached to the stent and unable to be deployed. At the same time, the support rod is arranged in the grid of the stent, and does not affect the loaded tube diameter during pre-installation, which is beneficial to the access delivery through the blood vessels.

[0024] 3. Due to the size limitation of the opening of the positioning members, the existing valves with positioning members are very difficult to insert into the sinuses during clinical operation due to different anatomical structures and insufficient opening of the positioning members. The operator needs to make repeated attempts to complete the insertion, which increases the difficulty of the operation and greatly prolongs the operation time. Different from the prior art, an embodiment of the present application utilizes a support rod to connect the positioning member, so that after the two ends of the expandable stent are compressed, one end of the support rod gathers toward the center of the stent, and the other end of the support rod drives the positioning member to the outside of the expandable stent, so that when the positioning member captures the autologous leaflets, the outward size of the positioning member can be significantly increased, making it easier to capture the leaflets. In addition, the anti-reflux pocket makes up for the defect that there is no autologous leaflet separation between adjacent positioning members, which makes reflux easy to occur, and the clinical effect is excellent.

[0025] 4. Different from the prior art, the connection structure in one embodiment of the present application is a grid-like structure, and the struts are arranged in the grid of the connection structure; such a design has at least two advantages: first, when the valve prosthesis is compressed and loaded, the loading tube diameter will not increase, which is conducive to transvascular access delivery; second, the struts are arranged in the grid, when the positioning member does not capture the leaflet ideally or other problems occur in the valve prosthesis, the struts will not affect the recovery of the valve prosthesis at all, thereby improving the fault tolerance of the device.

[0026] The embodiments of the present application can achieve other beneficial technical effects that are not listed one by one. These other technical effects may be partially described below and can be anticipated and understood by those skilled in the art after reading the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The above-mentioned features and advantages and other features and advantages of these embodiments and the manner in which they are achieved will become more apparent, and the embodiments of the present application can be better understood by referring to the following description together with the accompanying drawings, in which:

[0028] Figures 1a to 1d Schematic diagram of the overall structure of the aortic prosthesis and the principle of formation of the anti-reflux pocket.

[0029] Figure 2a to 2c It is a structural schematic diagram of the positioning member and the connecting structure of the present invention.

[0030] Figure 3a to 3d It is a schematic diagram of the process of releasing the aortic prosthesis by the delivery system of the present invention and a schematic diagram of the anti-leakage mechanism preventing regurgitation at the junction of the valve leaflets. DETAILED DESCRIPTION

[0031] In the following description of the drawings and specific embodiments, the details of one or more embodiments of the present application will be described. From these descriptions, drawings and claims, other features, purposes and advantages of the present application can be clearly seen.

[0032] It should be understood that the illustrated and described embodiments are not limited in application to the details of the construction and arrangement of the components set forth in the following description or illustrated in the accompanying drawings. The illustrated embodiments may be other embodiments and may be implemented or executed in various ways. Each example is provided by explaining the disclosed embodiments rather than limiting them. In fact, it will be apparent to those skilled in the art that various modifications and variations may be made to the embodiments of the present application without departing from the scope or essence disclosed in the present application. For example, a feature illustrated or described as part of an embodiment may be used together with another embodiment to still produce another embodiment. Therefore, the present application discloses and covers such modifications and variations within the scope of the appended claims and their equivalent elements.

[0033] Likewise, it is understood that the phrases and terms used herein are for descriptive purposes and should not be considered restrictive. The use of "include," "comprise," or "have" and variations thereof herein is intended to be open-ended to include the items listed thereafter and their equivalents, as well as possible additional items.

[0034] As used herein, “axial” refers to a direction generally along the central axis of the aorta at the surgical site, and “transverse” refers to a direction generally transverse to, preferably perpendicular to, the “axial” direction.

[0035] The present application will be described in more detail below with reference to different embodiments and examples of several aspects of the present application.

[0036] In the present application, the proximal end refers to the end close to the apex of the heart, and the distal end refers to the end away from the surgical apex of the heart.

[0037] In one embodiment of the present invention, an aortic prosthesis capable of preventing reflux at the junction includes: a stent 1 for supporting and anchoring, a positioning member 2 for positioning and clamping an autologous valve leaflet, and a leak-proof mechanism 3, wherein the stent 1 includes a plurality of expandable diamond-shaped grids 11, the leak-proof mechanism 3 includes a sealing membrane 31 and a support rod 32, one end of the support rod 32 is connected to the diamond-shaped grids 11 between adjacent positioning members 2, and extends downward to form a filling portion 33 convex to the outside of the stent 1, and the support rod 32 is provided with a sealing membrane 31 and a support rod 32. The other end of the rod 32 is free, and the sealing film 31 is connected to the diamond grid 11; wherein, when the aortic prosthesis is installed in place, the filling part 33 is located at the junction of the native valve leaflets and abuts against the vascular tissue, so that the filling part 33 drives the other end of the support rod 32 to tilt toward the outside of the stent 1 with the connection point between the support rod 32 and the diamond grid 11 as a fulcrum, and the sealing film 31 is unfolded with the support rod 32 and forms an anti-reflux pocket 34 to prevent blood reflux, such as Figures 1a to 1c shown.

[0038] In this embodiment, the positioning member 2 includes a positioning portion 21 and a connecting portion 22. Figure 2a and 2b As shown, the stent 1 is provided with a plurality of connecting structures 5 at the distal end, the connecting structure 5 is provided with a support rod 51, and one end of the support rod 51 is connected to the connecting portion 22 of the positioning member 2, and the other end of the support rod 51 is connected to the connecting structure 5, as shown in FIG. Figure 2c As shown; when the valve prosthesis reaches the target position, the positioning portion 21 of the positioning member 2 is released, and the two ends of the stent 1 are restricted, so that the proximal end of the strut 51 is propped up toward the outside of the stent 1 relative to the distal end of the strut 51, and drives the positioning portion 21 of the positioning member 2 to prop up toward the outside of the stent 1.

[0039] In this embodiment, the connecting structure 5 is a grid-like structure, and the support rod 51 is arranged in the grid of the connecting structure 5, wherein one end of the support rod 51 is fixedly connected to the connecting structure 5, and the other end of the support rod 51 is free, and the other end of the support rod 51 is bent or inclined toward the inside of the stent 1; the purpose of such design is that the connecting portion 21 of the positioning member 2 is connected to the other end of the support rod 51, so that the positioning portion 21 of the positioning member 2 can be closely attached to the outside of the stent in a natural state, thereby significantly improving the clamping force of the positioning member 2 and enhancing the anchoring effect of the valve prosthesis.

[0040] In this embodiment, in a natural state, the positioning portion 21 of the positioning member 2 is in close contact with the outer side of the stent 1; the design of the support rod 51 enables the positioning member 2 to open to a larger angle toward the outer side of the stent 1 when capturing the leaflets. At the same time, after capturing the leaflets, the positioning member 2 can provide a strong clamping force so that the valve prosthesis can be stably anchored in the heart.

[0041] In this embodiment, in a natural state, the filling portion 33 and the support rod 32 are provided with a certain angle, such as Figure 1c As shown, after the filling portion 33 is squeezed, the other end of the support rod 32 can be pried to swing toward the outside of the stent 1, so that the support rod 32 is close to the blood vessel wall, and the sealing film 31 is unfolded with the swing of the support rod 32 to form an anti-reflux pocket 34 to prevent blood reflux. Figure 3d shown.

[0042] In this embodiment, the stent 1 has an inflow end and an outflow end. When the aortic prosthesis is installed in place, the support rod 32 and the sealing membrane 31 are located at the outflow end of the stent 1, and the anti-reflux pocket 34 is located at the junction of the native valve leaflets.

[0043] In this embodiment, when the aortic prosthesis is installed in place, the filling portion 33 drives the other end of the support rod 32 to abut against the vascular tissue. Figure 3c and 3d shown.

[0044] In this embodiment, during preinstallation, the support rod 32 enters the diamond grid 11, and the length of the support rod 32 is less than or equal to the axial length of the diamond grid 11; the advantage of this design is that the support rod 32 does not occupy the space of the delivery sheath during preinstallation, which can reduce the diameter of the delivery sheath and facilitate transvascular access.

[0045] In this embodiment, when pre-installed, the filling portion 33 enters the gap between the adjacent diamond grids 11, and the free end of the filling portion 33 does not extend axially to the outside of the stent 1; the advantage of this design is that the filling portion 33 does not occupy the space of the delivery sheath when pre-installed, which can reduce the diameter of the delivery sheath and facilitate transvascular access.

[0046] In this embodiment, the other end of the support rod 32 is provided with an attachment structure 321. Figure 1d As shown, when the aortic prosthesis is installed in place, the attachment structure 321 of the support rod 32 adheres to the blood vessel wall; the attachment structure 321 is relatively flexible, so that the support rod 32 can avoid puncturing the blood vessel tissue when it is attached to the blood vessel wall.

[0047] In this embodiment, the connection point between the support rod 32 and the diamond grid 11 is located at the native valve annulus, and when the aortic prosthesis is installed in place, the filling portion 33 is against the native valve annulus tissue; and the filling portion 33 is located at the junction of the native valve leaflets. After the positioning member 2 clamps the valve leaflets, there is no native valve leaflet to block the junction, so regurgitation is more likely to occur. The filling portion 33 is against the native valve annulus and is located at the junction of the native valve leaflets, which can drive the support rod 32 and the sealing membrane 31 to prevent leakage at the junction of the valve leaflets.

[0048] In this embodiment, the sealing film 31 is made of biological tissue, fabric or polymer material.

[0049] In this embodiment, the free end of the filling portion 33 is bent, and the filling portion 33 is covered with a fabric layer having a buffering effect; the purpose of such a design is that the filling portion 33 can effectively avoid puncturing the tissue when it abuts against the tissue.

[0050] According to another example, the free end of the filling portion 33 is flat, and the free end of the filling portion 33 can adaptively fit the autologous valve ring tissue located at the junction of the autologous valve leaflets. Furthermore, the free end of the filling portion 33 is covered with fabric. The advantage of this design is that the filling portion 33 can further fill the position of the autologous valve ring tissue at the junction of the autologous valve leaflets, and the anti-reflux pocket 34 formed by the support rod 32 and the sealing membrane 31 can achieve double leakage protection for the junction of the valve leaflets.

[0051] In this embodiment, a delivery system 4 is also included, and the delivery system 4 includes an outer sheath tube 41 and a withdrawal sheath 42. The withdrawal sheath 42 constrains the proximal end of the stent 1, and the anti-leakage mechanism 3 is also constrained in the withdrawal sheath 42 during pre-installation. When the delivery system 4 is transported to the target position with the aortic prosthesis, the outer sheath tube 41 is operated and withdrawn toward the operator's end. At this time, the positioning member 2 is released, as shown in FIG. Figure 3aAs shown, the positioning part of the positioning member 2 is positioned at the position of the aortic sinus bottom, and then the withdrawal sheath 42 is operated to make the leakage prevention mechanism 3 extend from the withdrawal sheath 42, and the proximal part of the stent 1 is released. At this time, the filling part 33 abuts against the autologous valve ring tissue, so that the filling part 33 drives the other end of the support rod 32 to tilt toward the outside of the stent 1, and the support rod 32 cooperates with the sealing membrane 31 to form an anti-reflux pocket 34 at the junction of the valve leaflets, which can fill and occupy the position of the junction of the valve leaflets, as shown in FIG. Figure 3b As shown, it effectively prevents blood reflux.

[0052] The foregoing description of the exemplary embodiments of the present application is presented for the purpose of illustration. The foregoing description is not intended to be exhaustive, nor is it intended to limit the present application to the precise configuration and / or construction disclosed, and it is apparent that, based on the teachings above, a person skilled in the art may make many modifications and variations without departing from the present invention. The scope and equivalents of the present invention are intended to be defined by the appended claims.

Claims

1. An aortic prosthesis capable of preventing commissural regurgitation, comprising a stent for supporting and anchoring, a positioning member for positioning and clamping a native valve leaflet, and a leak-proof mechanism, wherein the stent comprises a plurality of expandable diamond-shaped grids, characterized in that: The anti-leakage mechanism includes a sealing film and a supporting rod, one end of the supporting rod is connected to the diamond grid between adjacent positioning members and extends downward to form a filling portion protruding to the outside of the bracket, the other end of the supporting rod is free, and the sealing film is connected to the diamond grid; Among them, when the aortic prosthesis is installed in place, the filling part is located at the junction of the autologous valve leaflets and abuts against the vascular tissue, so that the filling part drives the other end of the support rod to tilt toward the outside of the stent with the connection point between the support rod and the diamond grid as a fulcrum, and the sealing membrane unfolds with the support rod to form an anti-reflux pocket to prevent blood reflux.

2. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The positioning member includes a positioning portion and a connecting portion, the bracket is provided with a plurality of connecting structures at the distal end, the connecting structure is provided with a support rod, and one end of the support rod is connected to the connecting portion of the positioning member, and the other end of the support rod is connected to the connecting structure; When the aortic prosthesis reaches the target position, the positioning portion of the positioning piece is released, and the two ends of the stent are restricted, so that the proximal end of the strut is propped up toward the outside of the stent relative to the distal end of the strut, and drives the positioning portion of the positioning piece to prop up toward the outside of the stent.

3. The aortic prosthesis capable of preventing commissural reflux according to claim 2, characterized in that: The connection structure is a grid-like structure, and the support rod is arranged in the grid of the connection structure, wherein one end of the support rod is fixedly connected to the connection structure, the other end of the support rod is free, and the other end of the support rod is bent or inclined toward the inside of the bracket.

4. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The stent has an inflow end and an outflow end. When the aortic prosthesis is installed in place, the support rod and the sealing membrane are located at the outflow end of the stent, and the anti-reflux pocket is located at the junction of the native valve leaflets.

5. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: When the aortic prosthesis is installed in place, the filling portion drives the other end of the supporting rod to abut against the vascular tissue.

6. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: During pre-installation, the support rod enters into the diamond grid, and the length of the support rod is less than or equal to the axial length of the diamond grid.

7. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: During pre-installation, the filling portion enters the gap between the adjacent diamond-shaped grids, and the free end of the filling portion does not axially extend to the outside of the stent.

8. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The other end of the support rod is provided with an attachment structure, and when the aortic prosthesis is installed in place, the attachment structure of the support rod fits the blood vessel wall.

9. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The connection point between the support rod and the diamond grid is located at the autologous valve ring, and when the aortic prosthesis is installed in place, the filling part abuts against the autologous valve ring tissue.

10. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The sealing film is made of biological tissue, fabric or polymer material.

11. The aortic prosthesis capable of preventing commissural reflux according to claim 1, characterized in that: The free end of the filling part is bent, and the filling part is covered with a fabric layer having a buffering effect.

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