Inhalation device

Abstract

The present application discloses an inhalation device, which includes a cover body, a mouthpiece, a filter element, a cover plate, a capsule chamber, a piercing assembly and a base. Among them, air inlets are respectively provided on the front side and the rear side of the cover plate, so as to form a double-sided air intake channel when negative pressure is generated in the inhalation channel of the mouthpiece. The inhalation device in the present application enables the inhalation device to generate an ideal air flow direction in the use state through the double-sided air intake design, helps the capsules in the capsule chamber to generate movements such as vibration and / or rotation to release the drug powder, and ensures the inhalation efficiency.

Description

Technical Field

[0001] This application relates to the technical field of medical devices, and particularly to an inhalation device. Background Art

[0002] In current drug administration methods, for some respiratory diseases, drugs can be ingested by direct inhalation. For example, when using the drug, a special drug delivery device is used to pierce a capsule containing drug powder and inhale the drug powder into the respiratory tract. However, in the existing technology, common drug delivery devices cannot effectively ensure the air intake efficiency due to structural design defects and cannot achieve an ideal air flow direction. Summary of the Invention

[0003] In view of the above-mentioned disadvantages of the related art, the purpose of this application is to provide an inhalation device to overcome the technical problems of low air intake efficiency of the drug delivery device and inability to achieve an ideal air flow direction existing in the above-mentioned related art.

[0004] To achieve the above purpose and other related purposes, an inhalation device is provided, including: a mouthpiece, including a mouthpiece body and an inhalation channel formed in the mouthpiece body; a filter element, disposed at the bottom end of the inhalation channel, for blocking capsule debris generated after the capsule is pierced; a cover plate, disposed below the mouthpiece and provided with a capsule placement opening corresponding to the filter element, and a first air inlet and a second air inlet are respectively provided on the near side and the far side of the cover plate; a capsule chamber, located below the cover plate and having a chamber for accommodating the capsule in the use state, and the chamber communicates with the capsule placement opening of the cover plate; a piercing assembly, including a button member and a needle movably disposed on one side of the capsule chamber, and the button member moves towards the capsule chamber in the pressed state to drive the needle to pierce the capsule in the capsule chamber; a base, including a seat body for accommodating the capsule chamber and part of the piercing assembly, and in the state where the cover plate is covered on the base, a first air intake channel from the first air inlet to the chamber and a second air intake channel from the second air inlet to the chamber are formed; a cover body, covering the mouthpiece in a state of being engaged with the base; wherein, when negative pressure is generated in the chamber, the air flows in the first air intake channel and the second air intake channel converge at the bottom end of the chamber and enter the chamber, and the drug powder in the pierced capsule in the chamber enters the inhalation channel through the capsule placement opening via the filter element.

[0005] In some embodiments of this application, the base, the cover plate and the distal end of the mouthpiece are coaxially connected through a first hinge portion, the cover body and the distal end of the base are coaxially connected through a second hinge portion, and the first hinge portion and the second hinge portion are not coaxial.

[0006] In certain embodiments of the present application, first engaging portions are provided on both sides of the cover body, passing through the first air inlet for engaging with the edges on both sides of the seat body of the base.

[0007] In certain embodiments of the present application, the tip of the lancet is formed by the intersection of three oblique planes at the same point, and the tip does not coincide with the extension line of the axis of the lancet.

[0008] In certain embodiments of the present application, the diameter of the lancet is 1 mm to 2 mm.

[0009] In certain embodiments of the present application, the number of lancets is two and they are arranged vertically. The distance between the two vertically arranged lancets is less than the height of the capsule and greater than half of the height of the capsule.

[0010] In certain embodiments of the present application, the nozzle body includes: an operation part located on the proximal side of the nozzle body for operating during use to bring the nozzle body closer to or away from the cover plate; a suction port part integrally formed with the operation part, having the suction channel and an outer contour adapted to the human mouth.

[0011] In certain embodiments of the present application, the proximal end of the operation part has a concave structure.

[0012] In certain embodiments of the present application, there is an operation mark at the concave structure.

[0013] In certain embodiments of the present application, the ratio of the cross-sectional area of the suction channel to the total area of the first air inlet and the second air inlet is 1:4.5 to 1:3.5.

[0014] In certain embodiments of the present application, the filter element includes a mounting part for mounting in the suction channel and a screening part for filtering.

[0015] In certain embodiments of the present application, the bottom of the suction channel is in a tubular structure, and the outer surface of the bottom end of the tubular structure and the inner surface of the mounting part of the filter element have corresponding mounting structures to arrange the filter element at the bottom end of the tubular structure.

[0016] In certain embodiments of the present application, the screening part includes a circular arc convex surface at the center and a retaining edge along the circumference of the circular arc convex surface.

[0017] In certain embodiments of the present application, the mesh diameter of the screening part is less than or equal to 0.6 mm to 1 mm.

[0018] In certain embodiments of the present application, the wire diameter of the screening part is 0.1 mm to 0.5 mm.

[0019] In certain embodiments of the present application, the ratio of the total area of the mesh holes of the mesh part to the total area of the first air inlet and the second air inlet is 1:3 to 1:2.

[0020] In certain embodiments of the present application, the mesh part is made of stainless steel.

[0021] In certain embodiments of the present application, the mesh part and the mounting part are integrally formed by ultrasonic welding, and thus a raised ring is formed on the surface of the mounting part.

[0022] In certain embodiments of the present application, the opposite surface of the filter element and the cover plate has end faces with matching shapes, so that the filter element and the cover plate are closely attached.

[0023] In certain embodiments of the present application, a plurality of air holes are evenly distributed on the opposite surface of the cover plate to the filter element, which are used to help generate turbulence in the chamber when a negative pressure is generated in the chamber, so that the capsule vibrates and / or rotates.

[0024] In certain embodiments of the present application, the mounting part includes two second engaging parts located at the proximal end and extending downward, and the cover plate has engaging holes corresponding to the two second engaging parts respectively, so as to realize the engagement of the nozzle and the cover plate.

[0025] In certain embodiments of the present application, the lower surfaces of the front and rear sides of the cover plate have raised parts; a supporting part corresponding to and engaging with the raised parts is formed at the top of the inner side wall of the base, which is used to realize the sealing and mutual support with the front and rear sides of the base when the cover plate is covered on the base.

[0026] In certain embodiments of the present application, a third engaging part is provided on the raised part, and a fourth engaging part corresponding to the third engaging part is provided on the upper side edge of the base.

[0027] In certain embodiments of the present application, the two sides of the cover plate respectively have fifth engaging parts, and the upper side edge of the base has sixth engaging parts corresponding to the fifth engaging parts.

[0028] In certain embodiments of the present application, the number of the first air inlets is two, which are respectively located at the front and rear sides of the proximal end of the cover plate.

[0029] In certain embodiments of the present application, the area of each of the first air inlets is 3.5 - 15 mm 2 。

[0030] In certain embodiments of the present application, the number of the second air inlets is two, which are opened on both sides of the distal end of the cover plate.

[0031] In some embodiments of the present application, a third air inlet is further provided on the distal side of the base. In a state where the cover plate is combined with the base, the third air inlet communicates with the second air inlet.

[0032] In some embodiments of the present application, the number of the second air inlets is one, and it is provided at the distal end of the cover plate.

[0033] In some embodiments of the present application, the cover plate and the capsule chamber are integrally formed.

[0034] In some embodiments of the present application, the chamber of the capsule chamber includes a main chamber, and the transverse diameter of the main chamber is greater than the transverse cross-sectional diameter of the capsule and less than the longitudinal cross-sectional diameter of the capsule.

[0035] In some embodiments of the present application, the ratio of the cross-sectional area of the main chamber to the total area of the first air inlet and the second air inlet is 1:2 to 1:1.5.

[0036] In some embodiments of the present application, a secondary chamber communicating with the main chamber is provided at the bottom of the chamber of the capsule chamber. The bottom end of the secondary chamber has a chamber air inlet, and there is a gap between the chamber air inlet and the bottom surface of the base. The diameter of the secondary chamber is less than the transverse cross-sectional diameter of the capsule.

[0037] In some embodiments of the present application, the ratio of the cross-sectional area of the chamber air inlet to the total area of the first air inlet and the second air inlet is 1:8 to 1:7.

[0038] In some embodiments of the present application, the chamber of the capsule chamber includes a mounting structure for cooperating with the piercing assembly so that the piercing assembly uses its piercing needle to pierce the capsule in the capsule chamber during the movement relative to the capsule chamber.

[0039] In some embodiments of the present application, the mounting structure includes: a mounting plate provided with symmetric card slots; a abutting portion formed on the mounting plate and located between the symmetric card slots; two tube portions formed on the mounting plate and respectively located on the upper and lower sides of the abutting portion, communicating with the chamber, and used to limit the piercing direction of the piercing needle.

[0040] In some embodiments of the present application, the piercing assembly further includes a reset mechanism located between the button member and the abutting portion, and is used to be pressed when the button member moves towards the capsule chamber to provide a reset force to make the piercing needle and the button member return to the initial position.

[0041] In some embodiments of the present application, a mounting block for mounting the reset mechanism is provided on the button member.

[0042] In some embodiments of the present application, the lancet is disposed within the tube portion, and the proximal end of the lancet is cooperatively connected to the button member.

[0043] In some embodiments of the present application, the button member includes a pressing portion and a movable connection portion integrally formed with the pressing portion, and the distal end of the movable connection portion has a limiting portion that cooperates with the card slot.

[0044] In some embodiments of the present application, the distal ends of the lancet and the movable connection portion are located on the same vertical line.

[0045] In some embodiments of the present application, an opening is provided at the proximal end of the base to provide a movement space for the piercing assembly.

[0046] In some embodiments of the present application, the base further includes a transparent window mounted on the seat body, and the chamber of the capsule chamber has a transparent wall surface for observing the state of the capsule in the capsule chamber through the base in the use state.

[0047] In some embodiments of the present application, the transparent window is located at the distal end of the base and extends to the front and rear sides of the base.

[0048] In some embodiments of the present application, a flow limiting plate with air flow guiding holes is provided inside the base to limit the size of the air flow and control the air intake direction of the air flow.

[0049] In some embodiments of the present application, the flow limiting plate is located on the side closer to the distal end inside the base.

[0050] In some embodiments of the present application, the number of the air flow guiding holes is two, symmetrically opened on the flow limiting plate, and the area of each air flow guiding hole is 20-35 mm 2 。

[0051] In some embodiments of the present application, the total area of the first air inlet and the second air inlet is 50-100 mm 2 。

[0052] In summary, the inhalation device in the present application has a bilateral air intake design, and through multiple designs such as the screen structure, the air holes at the capsule insertion port, and the flow limiting plate, an ideal air flow direction is generated in the use state of the inhalation device, helping the capsules in the capsule chamber to vibrate and / or rotate to release the drug powder, ensuring the inhalation efficiency. Moreover, the inhalation device in the present application can achieve button - opened lid through the cooperation between the button member, the cover body, and the base, which is convenient to use. In addition, multiple designs such as the double - axis connection of the inhalation device and the supporting structure of the cooperation between the cover plate and the base can ensure the service life of the product; the concave structure of the nozzle operation part can ensure the hygiene and cleanliness during use, and the positional relationship between the puncture needle and the movable connection part is convenient for sensing the puncture position, with convenient operation and conforming to the ergonomic design.

[0053] Those skilled in the art can easily insight into other aspects and advantages of the present application from the following detailed description. Only the exemplary embodiments of the present application are shown and described in the following detailed description. As those skilled in the art will recognize, the content of the present application enables those skilled in the art to make changes to the disclosed specific embodiments without departing from the spirit and scope of the invention involved in the present application. Accordingly, the descriptions in the drawings and the specification of the present application are merely exemplary and not restrictive. BRIEF DESCRIPTION OF THE DRAWINGS

[0054] The specific features of the invention involved in the present application are shown in the appended claims. The features and advantages of the invention involved in the present application can be better understood by referring to the exemplary embodiments and the drawings described in detail below. A brief description of the drawings is as follows:

[0055] Figures 1a to 1c Shows an exploded view of the structure of the inhalation device in an embodiment of the present application;

[0056] Figure 2a Shows an exploded view of the structure of the filter element in an embodiment of the present application;

[0057] Figure 2b Shows a schematic view of the structure of the screen part and the installation part before welding in an embodiment;

[0058] Figure 2c Shows a schematic view of the structure of the screen part and the installation part after welding in an embodiment;

[0059] Figure 3 Shows a schematic view of the structure of the nozzle in an embodiment of the present application;

[0060] Figure 4 Shows a schematic view of the structure of the cover plate in an embodiment of the present application;

[0061] Figure 5Shown is a schematic diagram of the air flow direction inside the inhalation device in an embodiment of the present application;

[0062] Figure 6 Shown is a schematic structural diagram of the cover, cover plate and base in an embodiment of the present application;

[0063] Figure 7 Shown is a schematic diagram of the mating structure of the button member, cover plate, capsule chamber and cover in an embodiment of the present application;

[0064] Figures 8a to 8c Shown is a schematic diagram of the mating structure of the button member, cover plate, capsule chamber and cover in another embodiment of the present application;

[0065] Figure 9 Shown is a schematic structural diagram of the cover plate and base in an embodiment of the present application;

[0066] Figure 10 Shown is a schematic structural diagram of the filter element and cover plate in an embodiment of the present application;

[0067] Figure 11 Shown is a schematic structural diagram of the cover plate, capsule chamber and capsule in an embodiment of the present application;

[0068] Figure 12 Shown is a schematic structural diagram of the capsule in an embodiment of the present application;

[0069] Figure 13 Shown is a schematic diagram of the mouthpiece, filter element and cover plate in an embodiment of the present application;

[0070] Figure 14 Shown is a schematic structural diagram of the cover plate in another embodiment of the present application;

[0071] Figure 15 Shown is a schematic structural diagram of the lancet in an embodiment of the present application;

[0072] Figure 16 Shown is a schematic structural diagram of the button member in an embodiment of the present application;

[0073] Figure 17 Shown is a schematic structural diagram of the mounting structure in an embodiment of the present application;

[0074] Figure 18a 、 Figure 18b Shown is a schematic structural diagram of the button member in another embodiment of the present application;

[0075] Figure 19 Shown is a schematic structural diagram of the piercing assembly in an embodiment of the present application;

[0076] Figure 20 Show the schematic structural diagram of the button member in another embodiment of the present application;

[0077] Figure 21 Show the schematic structural diagram of the lancet and the button member in an embodiment of the present application;

[0078] Figure 22 Show the schematic structural diagram of the base in an embodiment of the present application;

[0079] Figure 23 Show the schematic structural diagram of the cover plate in another embodiment of the present application;

[0080] Figure 24 Show the schematic structural diagram of the cover plate and the base in another embodiment of the present application;

[0081] Figure 25 Show the schematic structural diagram of the base in yet another embodiment of the present application;

[0082] Figure 26 Show the schematic diagram of the airflow direction of the inhalation device in an embodiment of the present application. Detailed implementation manners

[0083] The following specific embodiments illustrate the implementation manners of the present application. Those skilled in the art can easily understand other advantages and effects of the present application from the content disclosed in this specification.

[0084] In the following description, reference is made to the accompanying drawings, which describe several embodiments of the present application. It should be understood that other embodiments may also be used, and changes in the composition of modules or units, electrical, and operations may be made without departing from the spirit and scope of the present disclosure. The following detailed description should not be considered restrictive, and the scope of the embodiments of the present application is only defined by the claims of the published patent. The terms used herein are only for describing specific embodiments and are not intended to limit the present application.

[0085] Although in some instances the terms first, second, etc. are used herein to describe various elements, information, or parameters, these elements or parameters should not be limited by these terms. These terms are only used to distinguish one element or parameter from another. For example, the first intake passage may be referred to as the second intake passage, and similarly, the second intake passage may be referred to as the first intake passage, without departing from the scope of the various described embodiments. The first intake passage and the second intake passage are both describing an intake passage, but they are not the same intake passage unless the context clearly indicates otherwise. Depending on the context, the word "if" as used herein may be interpreted as "when" or "while".

[0086] Furthermore, as used herein, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly dictates otherwise. It should be further understood that the terms "comprising", "including" indicate the presence of the stated features, steps, operations, elements, components, items, kinds, and / or groups, but do not preclude the presence, occurrence, or addition of one or more other features, steps, operations, elements, components, items, kinds, and / or groups. The terms "or" and "and / or" as used herein are to be construed as inclusive, or meaning any one or any combination. Thus, "A, B, or C" or "A, B, and / or C" means "any of the following: A; B; C; A and B; A and C; B and C; A, B, and C". Exceptions to this definition occur only when the combination of elements, functions, steps, or operations is inherently mutually exclusive in some manner.

[0087] As described in the background art, in some embodiments, a dosing device for treating respiratory diseases generally has an air intake passage to provide an air flow. However, in some embodiments, such a dosing device generally has only one air intake passage, and the air intake volume is limited. Moreover, the design of these air intake passages cannot achieve an ideal air flow direction, thereby affecting the inhalation efficiency of the drug powder in the capsule. Furthermore, in some related technologies, some detailed designs of the dosing device are not user-friendly enough. For example, the mouthpiece part for docking with the human mouth is easily contaminated during operation, and it is inconvenient to operate when opening the dosing device, resulting in a poor user experience.

[0088] In view of the fact that the inhalation efficiency of the inhalation device of the dosing device has a significant impact on the dosing efficiency and dosing effect, and the requirements of such devices for hygiene and other aspects, the present application provides an inhalation device. In an embodiment, the inhalation device is a dosing device for facilitating a patient to inhale drug powder from a capsule containing powdered drug through the respiratory tract. In some usage scenarios, the inhalation device as the dosing device is also referred to as an inhaler, a powder inhaler, or a dry powder inhaler, etc. In use, the patient can load the capsule into a capsule chamber located in the inhaler before use, and then the patient can press a button that can drive a needle to convert the needle from a stationary state to a moving state to puncture the capsule located in the capsule chamber, so that the capsule releases the powdered drug therein under negative pressure. Examples of the powdered drug include, but are not limited to, drugs that can be administered by inhalation through the respiratory tract such as Tiotropium Bromide and Indacaterol.

[0089] In an exemplary embodiment, refer to Figures 1a to 1c, which shows a schematic exploded view of the inhalation device in an embodiment of the present application. As shown in the figure, the inhalation device includes a cover 1, a mouthpiece 2, a filter element 3, a cover plate 9, a capsule chamber 4, a piercing assembly 5, and a base 6.

[0090] The cover is a component for covering the mouthpiece 2 in a state of being engaged with the base 6 to prevent the mouthpiece from being contaminated by the outside.

[0091] In the present application, the engagement means a physical mating method in which two components can quickly or conveniently achieve a fixed state or a separated state with each other by using mechanical deformation (such as interference fit) or mechanical interference. In an embodiment, for example, the mating methods of a hook and a slot, a hook and a hook, or a protrusion and a groove, a protrusion and a protrusion, etc. In the present application, the engagement structure between two components will be described with reference to the mechanical structures of different components in their respective specific implementation states and in combination with the drawings.

[0092] The mouthpiece is a component for cooperating with the human mouth to inhale the drug powder in the capsule in the capsule chamber into the body. In this embodiment, please refer to Figure 3 , which shows a schematic structural view of the mouthpiece in an embodiment of the present application. The inhalation channel 22 is integrally formed in the mouthpiece body 21.

[0093] In the present application, the integrally formed structure means a structure in which multiple components with their respective functions are integrated into one body and cannot be physically disassembled by non-destructive means. It is usually fused into one body during the manufacturing stage, such as being integrally formed by mold injection or by additive manufacturing (3D printing), etc.

[0094] The filter element is a component for filtering the objects in the capsule chamber and facilitating the generation of a high-efficiency inhalation airflow. In an embodiment, please continue to refer to Figures 1a to 1c , the filter element 3 is sleeved at the bottom of the inhalation channel 22.

[0095] The cover plate 9 is located below the mouthpiece. The cover plate 9 is provided with a capsule insertion opening 91, and the capsule insertion opening 91 communicates with the capsule chamber 4. In the use state, the patient places the capsule into the capsule chamber 4 through the capsule insertion opening 91. The capsule insertion opening 91 is correspondingly combined with the filter element 3 to ensure a tight combination with the filter element to guarantee the inhalation efficiency.

[0096] The capsule chamber is a component for accommodating the capsule and maintaining connections with the piercing assembly, the cover plate, and the base. Please continue to refer to Figure 1c, the capsule chamber is located below the cover plate 9. The capsule chamber includes a chamber 42 for accommodating the capsule. In an embodiment, when the capsule is placed in the chamber 42, it is generally in an upright state, that is, one end of the capsule is located at the bottom of the chamber 42, and one end of the capsule is close to the top of the chamber 42. In some embodiments, the cover plate 9 and the capsule chamber 4 may also be an integrally formed structure, enabling seamless connection between the two, reducing manufacturing costs and difficulties, and reducing material and production costs.

[0097] Please refer to Figure 4 , which shows a schematic structural diagram of the cover plate in an embodiment of the present application. As shown in the figure, a first air inlet 92 and a second air inlet 93 are respectively provided on the near side and the far side of the cover plate 9. In the state where the cover plate 9 is closed on the base 6, a first air intake passage from the first air inlet 92 to the chamber 42 and a second air intake passage from the second air inlet 93 to the chamber 42 are formed.

[0098] In the present application, the term "connected" means being spatially connected so that air flow or drug powder carried by the air flow can pass through. In some expressions, the term "connected" is also used as "linked", both referring to the spatial connection of two physical spaces.

[0099] Here, it should be noted that the capsule is not necessarily a part of the inhalation device. In some cases, to avoid the powder in the capsule from getting damp, the capsule is only taken out and placed in the capsule chamber during use to suck the drug powder in the capsule.

[0100] The piercing assembly is a component for piercing the capsule in the capsule chamber. The piercing assembly 5 is located on one side of the capsule chamber 4. The piercing assembly 5 includes a button member 51 and a piercing needle 52. The button member 51 can move relative to the capsule chamber. A passage for the piercing needle to pass through is provided on the chamber of the capsule chamber 4. In the use state, when a pressing force is applied to the button member, the button member drives the piercing needle 52 to pierce the capsule in the chamber 42 while moving relative to the capsule chamber. In the present application, relative movement means that multiple components move closer to or away from each other relative to each other. Therefore, here, the button member can move relative to the capsule chamber means that the button member can move closer to or away from the capsule chamber.

[0101] The base is a component for accommodating the capsule chamber and serving as a part of the air flow channel, as well as for dust prevention and facilitating the user's holding and operation. The base 6 includes a base body 61. The interior of the base body 61 is a hollow structure for accommodating the chamber 42 of the capsule chamber and a part of the piercing assembly 5.

[0102] In the usage mode of this embodiment, first, the cover 1 and the nozzle 2 are opened, and the capsule is placed in the capsule insertion port 91 on the cover plate 9. The capsule enters the chamber 42 from the capsule insertion port 91. Then, the nozzle 2 is covered on the cover plate 9 so that the inhalation channel 22 communicates with the capsule insertion port 91. Next, the button member 51 drives the puncturing needle 52 to puncture the capsule located in the chamber 42 to form a drug powder outlet on the capsule. At this time, the user holds the upper part of the nozzle with the mouth and inhales, generating negative pressure in the inhalation channel. Please refer to Figure 5 , which shows a schematic diagram of the air flow direction in the inhalation device in this application in an embodiment. As shown in the figure, the air flows into the base (not shown) from the first air inlet channel and the second air inlet channel respectively, and converges at the bottom end of the chamber 42 and enters the chamber. Since the diameter of the drug powder is very fine, it can leave the capsule through the drug powder outlet of the capsule under the action of negative pressure, and enter the inhalation channel along with the air flow through the filter element and be inhaled into the user's body, while the possible capsule debris is blocked by the filter element 3 and does not enter the inhalation channel.

[0103] It should be understood that the terms "proximal" and "distal" used in this application are relative to the piercing assembly. Therefore, in each embodiment of this application, for the convenience of description, the side of the inhalation device close to the piercing assembly is defined as the proximal side, and the side far from the piercing assembly is defined as the distal side. That is, in this application Figure 1b , the side where the reference numerals 19, 29, 69b, and 99 are shown is the distal side, and the opposite side is the proximal side. In addition, the terms "front" and "rear" used in this application are for the convenience of explanation in terms of the viewing direction shown in the figure. Specifically, "front" in this application is defined as the left side facing the direction of the reference numerals 19, 29, 69b, and 99 with the direction of the piercing assembly as the reference, that is Figure 1a , the side closer to the viewing direction shown in the figure; "rear" in this application is defined as the right side facing the direction of the reference numerals 19, 29, 69b, and 99 with the direction of the piercing assembly as the reference, that is Figure 1a , the side farther from the viewing direction shown in the figure. It should also be understood that for the convenience of description, spatial terms such as "top surface" and "bottom surface" are used in this application in the placement state of the inhalation device presented in the figure. However, since the surgical medical device can be used in multiple directions and positions in various usage scenarios, these spatial terms are not restrictive and absolute.

[0104] In an exemplary embodiment, please continue to refer to Figure 4 , the number of the first air inlets 92 is two, which are respectively located on the front and rear sides of the proximal end of the cover plate. In a possible implementation manner, to achieve an ideal air intake volume, the area of each of the first air inlets is 3.5 - 15 mm 2 , such as 3.5 mm 2 , 4 mm 2 , 5 mm2 , 6 mm 2 , 7 mm 2 , 8 mm 2 , 9 mm 2 , 10 mm 2 , 11 mm 2 , 12 mm 2 , 13 mm 2 , 14 mm 2 , 15 mm 2 etc. In this embodiment, the area of each of the first air inlets is 9 mm 2 .

[0105] In some embodiments, the number of the first air inlets may also be one or more than two, as long as it can achieve air intake from the proximal side of the cover plate. For example, only one first air inlet is provided on one side of the proximal end of the cover plate, or multiple first air inlets are respectively provided on both sides of the proximal end of the cover plate, etc. Here, to ensure the suction efficiency, the total area of the added areas of each first air inlet may be 10 - 30 mm 2 , such as 10 mm 2 , 11 mm 2 , 12 mm 2 , 13 mm 2 , 14 mm 2 , 15 mm 2 , 16 mm 2 , 17 mm 2 , 18 mm 2 , 19 mm 2 , 20 mm 2 , 21 mm 2 , 22 mm 2 , 23 mm 2 , 24 mm 2 , 25 mm 2 , 26 mm 2 , 27 mm 2 , 28 mm 2 , 29 mm 2 , 30 mm 2 etc.

[0106] The number of the second air inlets may be one or multiple. For example, please refer to Figure 23 , which shows a schematic structural diagram of the cover plate in another embodiment of the present application. As shown in the figure, a second air inlet 93 is provided at the distal end of the cover plate. When a negative pressure is generated in the suction channel, on the one hand, the air flow can enter the base through the first air inlet 92 located on the proximal side of the cover plate, and on the other hand, the air flow can enter the base through this second air inlet 93 located on the distal side of the cover plate. Another example is as shown in Figure 4As shown, on both sides of the first hinge portion on the far side of the cover plate, there is respectively provided a second air inlet 93. When a negative pressure is generated in the suction channel, on the one hand, the air flow can enter the base through the first air inlet 92 located on the near side of the cover plate, and on the other hand, it can enter the base through the two second air inlets 93 located on the far side of the cover plate.

[0107] In some embodiments, please refer to Figure 24 , which shows a schematic structural diagram of the cover plate and the base in another embodiment of the present application. As shown in the figure, a third air inlet 65 may also be provided on the far side of the base. After the cover plate is engaged with the base, the third air inlet 65 can communicate with the second air inlet 93, that is, they cooperate together to form a notch. When a negative pressure is generated in the suction channel, a second air intake channel from the third air inlet 65 and the second air inlet 93 to the chamber can be formed.

[0108] In an exemplary embodiment, the total area of the first air inlet and the second air inlet can be in the range of 50 - 100 mm 2 , for example, 50 mm 2 , 51 mm 2 , 52 mm 2 , 53 mm 2 , 54 mm 2 , 55 mm 2 , 56 mm 2 , 57 mm 2 , 58 mm 2 , 59 mm 2 , 60 mm 2 , 61 mm 2 , 62 mm 2 , 63 mm 2 , 64 mm 2 , 65 mm 2 , 66 mm 2 , 67 mm 2 , 68 mm 2 , 69 mm 2 , 70 mm 2 , 71 mm 2 , 72 mm 2 , 73 mm 2 , 74 mm 2 , 75 mm 2 , 76 mm 2 , 77 mm 2 , 78 mm 2 , 79 mm 2 , 80 mm 2 , 81 mm 2 , 82 mm 2 , 83 mm 2, 84 mm 2 , 85 mm 2 , 86 mm 2 , 87 mm 2 , 88 mm 2 , 89 mm 2 , 90 mm 2 , 91 mm 2 , 92 mm 2 , 93 mm 2 , 94 mm 2 , 95 mm 2 , 96 mm 2 , 97 mm 2 , 98 mm 2 , 99 mm 2 , 100 mm 2 etc.

[0109] In an exemplary embodiment, for ease of use, the inhalation device may adopt a double-axis connection, that is, the cover body, the mouthpiece, the cover plate, and the base are respectively connected by two axes. For example, the base, the cover plate, and the distal end of the mouthpiece are coaxially connected through a first hinge portion, the cover body and the distal end of the base are coaxially connected through a second hinge portion, and the first hinge portion and the second hinge portion are not coaxial.

[0110] Please continue to refer to Figure 1b , the distal ends of the base 6, the cover plate 9, the mouthpiece 2, and the cover body 1 each have a hinge portion. Among them, the cover body and the base are coaxially connected through a second hinge portion (19, 69b), and the mouthpiece 2, the cover plate 9, and the base 6 are coaxially connected through a first hinge portion (29, 99, 69a). Therefore, the distal end of the base includes both a first hinge portion 69a and a second hinge portion 69b at the same time. Among them, the first hinge portion and the second hinge portion may be a shaft hole and realize the hinge between components through a connecting shaft. Or, the first hinge portion and the second hinge portion may be in the form of a convex block and a shaft hole to realize the hinge, as shown in Figure 1b . The first hinge portion 69a on the base and the first hinge portion 99 on the cover plate are both shaft holes, and the first hinge portion 29 on the mouthpiece 2 is an approximately circular protrusion to cooperate with the first hinge portion 69a and the first hinge portion 99 to realize the hinge. Similarly, the second hinge portion 19 on the cover body is a shaft hole, and the second hinge portion 69b on the base 6 is an approximately circular protrusion to cooperate with the second hinge portion 19 to realize the hinge. It should be noted that the positions of the shaft hole and the protrusion exemplified in this embodiment are only examples rather than limitations, and are not limited in specific applications. The positions of the shaft hole and the protrusion can also be interchanged, and the forms of the first hinge portion and the second hinge portion can also be other structures, as long as the hinge can be realized, it can be applied here.

[0111] In an exemplary embodiment, in order to better support and seal the base, the lower surfaces of both sides in the front and back of the cover plate have protruding portions, and a support portion corresponding to the protruding portions is formed at the top of the inner side wall of the base. When the cover plate is closed on the base, sealing and mutual support with the front and back sides of the base can be achieved.

[0112] Please refer to Figure 9 , which shows a schematic structural view of the cover plate and the base in an embodiment of the present application. As shown in the figure, both lower surfaces of the front and back sides of the cover plate respectively have a protruding portion 94, and a support portion 62 is provided at the top of the front and back inner side walls of the base. Here, the support portion 62 includes a stepped surface that cooperates with the protruding portion 94. When the cover plate is closed on the base, the protruding portion 94 cooperates with the support portion 62, so that on the one hand, it plays a role in strengthening the stress on both front and back sides of the base, avoiding deformation or damage of the base when being squeezed, and on the other hand, it can play a sealing role to ensure the suction efficiency.

[0113] In an exemplary embodiment, the cover plate and the base have corresponding engaging portions, so that the cover plate can be engaged on the base. Among them, the corresponding engaging portions can include one or more places, that is, the cover plate and the base can have a pair of corresponding engaging portions or multiple pairs of corresponding engaging portions.

[0114] In an embodiment, please continue to refer to Figure 9 , a third engaging portion 941 is provided on the protruding portion 94, and a fourth engaging portion 621 corresponding to the third engaging portion 941 is provided on the upper side edge of the base. Here, the third engaging portion 941 is a convex block, and the fourth engaging portion 621 is a groove, so as to realize the engagement of the cover plate and the base. It should be understood that in Figure 9 due to the angle relationship, the fourth engaging portion located on the front side cannot be directly observed, so in Figure 9 it is shown in dotted lines to indicate the position and engagement relationship with the third engaging portion 941; correspondingly, since the third engaging portion on the rear side is blocked in this view angle, it is not shown, but those skilled in the art should be able to obtain the position relationship of the third engaging portion and the fourth engaging portion on the rear side through the position relationship of the third engaging portion and the fourth engaging portion on the front side, which will not be elaborated here.

[0115] In another embodiment, please continue to refer to Figure 9 , both sides of the proximal end of the cover plate respectively have a fifth engaging portion 95, and a sixth engaging portion 64 corresponding to the fifth engaging portion 95 is provided on the upper side edge of the proximal end of the base. Here, the fifth engaging portion 95 is a convex block, and the sixth engaging portion 64 is a groove, so as to realize the engagement of the cover plate and the base. It should be understood that in Figure 9 due to the angle relationship, the sixth engaging portion located on the front side cannot be directly observed, so in Figure 9It is shown in dashed lines to indicate the position and engagement relationship with the fifth engaging portion 95.

[0116] It should be noted that in some embodiments, the third engaging portion may be provided only on the cover plate and the corresponding fourth engaging portion may be provided on the base; or the fifth engaging portion may be provided only on the cover plate and the corresponding sixth engaging portion may be provided on the base; or the third engaging portion and the fifth engaging portion may be provided on the cover plate at the same time, and the corresponding fourth engaging portion and the sixth engaging portion may be provided on the base. Moreover, the bump and groove structures in this embodiment are only examples of the engaging structure rather than limitations. In actual applications, the bump and the groove may also be replaced by other engaging structures, which will not be elaborated here.

[0117] In an exemplary embodiment, in order to prevent the cover from loosening in the non-use state and being unable to protect the nozzle, a matching engaging structure is provided between the cover and the base, so that the cover can be opened through the engaging structure to expose the nozzle during use, and the cover can be closed to cover the nozzle when not in use.

[0118] In one embodiment, the two sides of the cover are provided with first engaging portions, and the two side edges of the seat body of the base have seventh engaging portions that cooperate with the first engaging portions. The first engaging portions pass through the first air inlet and engage with the seventh engaging portions on the two side edges of the base seat body. Among them, the specific structure of the first engaging portion can be designed according to the engaging method between the cover and the base. For example, the first engaging portion can be a protruding structure. Correspondingly, the proximal side of the cover plate has a seventh engaging portion that cooperates with the protruding structure, such as an inclined surface or a groove. Or, the first engaging portion can include a hook-like structure. Correspondingly, the seventh engaging portion includes a protruding structure that engages with the hook-like structure.

[0119] Please refer to Figure 6 , which shows a schematic structural diagram of the cover, the cover plate, and the base in an embodiment of the present application. As shown in the figure, the two sides of the cover 1 are provided with first engaging portions 11. The first engaging portions 11 are located on the front and back sides of the inner wall of the cover. The first engaging portions 11 have hooks protruding toward the outside of the cover. And, seventh engaging portions 67 corresponding to the first engaging portions 11 are respectively provided on the front and back side edges of the seat body 61 of the base 6. Here, the seventh engaging portion 67 is a groove structure so that the hook structure of the first engaging portion 11 can engage with the groove. Here, the first engaging portions 11 on both sides of the cover respectively pass through the first air inlet 92 and engage with the two side edges of the seat body 61 of the base.

[0120] In some embodiments, when the position of the first air inlet opened on the cover plate does not correspond to the position of the first engaging portion, making the first engaging portion unable to pass through the first air inlet, an opening corresponding to the first engaging portion can also be opened on the cover plate to allow the first engaging portion to pass through.

[0121] It should be noted that the engaging structure between the cover and the base in this embodiment is only an example rather than a limitation. Moreover, in other embodiments, the cover can also be engaged with other components such as a cover plate to achieve masking of the nozzle, as long as corresponding engaging structures are provided on the cover and other components, which will not be elaborated here.

[0122] In an exemplary embodiment, when the cover is engaged with the base, the cover can be opened by the cooperation of a button member. In one embodiment, the upper distal end of the button member has an inclined surface. When the button member is in a pressed state, it moves towards the capsule chamber so that the inclined surface contacts the first engaging portion and pushes the first engaging portion upward to release the engagement between the cover and the base.

[0123] In one embodiment, please refer to Figure 7 , which shows a schematic structural diagram of the button member, the cover plate, the capsule chamber, and the cover in an embodiment of the present application. Here, to clearly show the cooperation relationship between the button member and the first engaging portion, the structure of the base is not shown. As shown in the figure, there is an inclined surface 514 at the upper distal side above the button member 51, and this inclined surface is used to cooperate with the first engaging portion 11 on the cover to open the cover. Specifically, when the cover is closed on the base, the first engaging portion on the cover is engaged with the seventh engaging portion on the base. When the button member 51 is pressed, the inclined surface 514 moves towards the distal side direction. The inclined surface 514 contacts the first engaging portion 11, and during the continuous movement of the button member towards the distal side, the first engaging portion 11 is pushed upward and finally the engagement with the seventh engaging portion is released to open the cover.

[0124] In another embodiment, please refer to Figures 8a to 8c , which shows a schematic diagram of the cooperation structure of the button member, the cover plate, and the cover in another embodiment, where Figure 8b is Figure 8a a schematic diagram from another angle, Figure 8c is Figure 8b an enlarged view of part A in Figure 8a . Here, to clearly show the structure and position of the button member, the structure of the capsule chamber is retained in the figure to show the positional relationship between the button member and the capsule chamber. As Figure 8b shown, when the cover plate is also provided with a fifth engaging portion 95 for engaging with the base, the first engaging portion 11 can be arranged in the advancing direction of the inclined surface, and the fifth engaging portion 95 can be arranged outside the advancing direction of the inclined surface to avoid interference. As

[0125] In an exemplary embodiment, please continue to refer toFigure 3 , as shown in the figure, the nozzle body 21 includes a suction port portion 211 and an operation portion 212. The operation portion 212 is used for operation during use to bring the nozzle body closer to or away from the cover plate. When the nozzle body approaches the cover plate, the nozzle body covers a part of the cover plate, for example, at least covers a part of the capsule placement opening on the cover plate, and exposes the first air inlet and the second air inlet on the cover plate, so as to connect the suction channel 22 with the capsule placement opening on the cover plate while enabling air to enter the base from the first air inlet and the second air inlet on the cover plate. As shown in Figure 3 , the suction port portion has an approximately flat oval structure adapted to the human mouth (mouth), which is convenient for the user to hold the upper part of the nozzle with the mouth, so as to form a negative pressure in the suction channel of the nozzle by inhaling in the state where the user's mouth wraps the upper part of the nozzle.

[0126] Among them, the operation portion 212 and the suction port portion 211 are integrally formed. Since the operation portion cooperates with the cover plate during use, and the suction port portion cooperates with the user's mouth, the operation portion and the suction port portion have different shapes to better conform to ergonomics. For this reason, there is a transition surface between the operation portion 212 and the suction port portion 211 to transition from the approximately flat oval structure of the suction port portion 211 to the operation portion structure that matches the shape of the cover plate.

[0127] In a possible implementation manner, please continue to refer to Figure 3 , a concave structure 2121 is provided at the proximal end of the operation portion, thereby forming a surface height difference at the proximal end of the operation portion. This surface height difference can facilitate the user to apply force to the nozzle to open or close it during use, so as to make the nozzle easy to operate while ensuring the hygiene of the suction port portion. In some embodiments, in order to prompt the user to operate the nozzle 2 through the concave structure 2121, an operation mark may be provided at the concave structure. The operation mark includes but is not limited to characters, patterns or colors, etc. to prompt the user.

[0128] As shown in Figure 1c , the filter element 3 is sleeved on the bottom of the suction channel 22. In this application, the term "sleeved on" means that due to the diameter difference between two components, a component with a larger diameter can be sleeved on a component with a smaller diameter. Therefore, on the one hand, the filter element 3 needs to play a filtering role to only allow the drug powder to pass through the suction channel; on the other hand, the filter element needs to be fixed to the bottom of the suction channel 22.

[0129] In one embodiment, please refer to Figure 2a, which shows a schematic exploded view of the filter element in an embodiment of the present application. As shown in the figure, the filter element 3 includes a mounting portion 31 and a screen portion 32. The screen portion 32 is used to block the capsule skin debris generated after the capsule is punctured, so as to avoid it entering the inhalation channel as much as possible. The mounting portion is used to be sleeved on the bottom end of the inhalation channel 22.

[0130] It should be noted here that in some cases, the blocking of the capsule debris is related to the diameter of the capsule debris and the filtration diameter of the filter element. For example, when the mesh diameter of the screen portion is 0.8 mm, the capsule debris with a diameter greater than 0.8 mm can be blocked.

[0131] In an exemplary embodiment, in order to facilitate the formation of a smooth air flow channel after the inhalation channel is combined with the capsule chamber, the bottom of the inhalation channel has a tubular structure, and the filter element is sleeved on the tubular structure at the bottom of the inhalation channel. Among them, the tubular structure can be a round tube, a square tube or other shaped pipes, etc., as long as it can allow the powder drug to pass through. However, considering the inhalation efficiency, a round tube, that is, a tubular structure with a circular cross-section, is adopted in this embodiment. In a possible implementation manner, the ratio of the cross-sectional area of the inhalation channel to the total area of the first air inlet and the second air inlet is 1:4.5 to 1:3.5 to ensure the inhalation efficiency.

[0132] In an embodiment, the outer surface of the bottom end of the tubular structure and the inner surface of the mounting portion of the filter element have corresponding mounting structures to dispose the filter element at the bottom end of the tubular structure, so that the filter element and the tubular structure can be firmly combined to ensure the use efficiency and safety.

[0133] In a possible implementation manner, please continue to refer to Figure 3 , a rib 221 is provided on the outer surface of the bottom end of the tubular structure 22 of the mouthpiece 2. Correspondingly, as Figure 2a shown, the inner surface of the mounting portion 31 of the filter element has an annular groove 311 that cooperates with the rib, so that when the filter element is installed on the tubular structure of the mouthpiece, the rib 221 can be clamped in the annular groove 311.

[0134] It should be noted that although the cooperation structure of the protruding ribs and the annular grooves is taken as an example in this embodiment, in actual applications, it is not limited to this. As long as the clamping effect between the filter element and the tubular structure can be achieved, for example, in other embodiments, the circle of protruding ribs in the above embodiment can be replaced by several bumps formed on the outer surface of the tubular structure, and the annular groove can be replaced by several concave holes formed on the inner surface of the filter element mounting part and corresponding to the several bumps one by one. Moreover, the positions of the protruding ribs and the annular grooves, or the bumps and the concave holes, can also be interchanged. For example, the inner surface of the mounting part of the filter element can be an annular groove while the outer surface of the bottom end of the tubular structure is a circle of protruding ribs, or the outer surface of the bottom end of the tubular structure can be several concave holes while the inner surface of the mounting part of the filter element is corresponding several bumps, etc., which will not be elaborated here.

[0135] In another embodiment, the screen part and the mounting part can also be an integrally formed structure, so as to facilitate manufacturing, production and assembly while taking into account the filtering and fixing functions.

[0136] In an exemplary embodiment, please continue to refer to Figure 2a , to form an ideal air flow direction, the screen part includes a circular arc convex surface at the center and a retaining edge along the circumference of the circular arc convex surface. In possible implementation manners, the circular arc convex surface and the retaining edge structure can be formed by stamping. In one implementation manner, the screen part is made of stainless steel material to facilitate stamping. In other implementation manners, the screen part can also be made of polymer material and formed by means of a mold or 3D printing.

[0137] In some implementation manners, to block capsule debris while ensuring the inhalation amount, the mesh hole diameter of the screen part is less than or equal to 0.6 mm to 1 mm, such as less than or equal to 0.6 mm, less than or equal to 0.7 mm, less than or equal to 0.8 mm, less than or equal to 0.9 mm, less than or equal to 1 mm, etc.; the wire diameter of the screen part is 0.1 mm to 0.5 mm, such as 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm; the ratio of the total area of the mesh holes of the screen part to the total area of the first air inlet and the second air inlet is 1:3 to 1:2.

[0138] It should be understood that the screen part includes several criss-crossing linear structures to form a mesh, the mesh openings of the mesh structure are the mesh holes, the wire diameter is the diameter of the linear structure, and the total area of the mesh holes of the screen part is the area amount after adding the areas of each mesh hole. The mesh holes can be circular or square, etc. For example, in one embodiment, the mesh holes can be squares with a side length of about 0.8 mm, or the mesh holes can also be circular structures with a diameter of about 0.7 mm, etc., which will not be elaborated one by one here.

[0139] The filter element in this application can control the flow direction of the flowing air through features such as the arc-shaped convex surface, the wire diameter of the screen mesh, and the mesh area, and at the same time, it can also prevent the patient from inhaling large pieces of broken capsule shells when vigorously inhaling the drug powder.

[0140] In an exemplary embodiment, the screen mesh part and the mounting part can be integrally formed by ultrasonic welding.

[0141] Please refer to Figure 2b 、 Figure 2c where Figure 2b shows a schematic structural diagram of the screen mesh part and the mounting part before welding in an embodiment, Figure 2c shows a schematic structural diagram of the screen mesh part and the mounting part after welding in an embodiment. As shown in Figure 2b 、 Figure 2c shown, during the ultrasonic welding process, a ring of protrusions 312 will be formed on the surface of the mounting part. Of course, in other embodiments, the screen mesh part and the mounting part can also be formed by injection molding and form protrusions.

[0142] In an exemplary embodiment, the contact surface between the filter element and the capsule chamber has end faces with matching shapes, so that when the suction nozzle and the cover plate are in a fitting state, the filter element can be pressed against the capsule insertion port and fit tightly with each other to avoid air leakage during use. In some embodiments, the capsule insertion port 91 corresponds to and is combined with the screen mesh part 32 to ensure a tight combination with the screen mesh part to guarantee the inhalation efficiency. And when the mounting part of the filter element has protrusions 312, these protrusions will help enhance the sealing between the filter element and the cover plate.

[0143] In a possible embodiment, please refer to Figure 10 which shows a schematic structural diagram of the filter element and the cover plate in this application in an embodiment. As shown in the figure, the outer surface of the lower part of the filter element has a stepped structure formed by the shape transition of the mounting part and the screen mesh part. Correspondingly, the upper inner surface of the capsule insertion port 91 of the cover plate has a shape corresponding to and matching this stepped structure, so that the filter element fits tightly with the capsule insertion port, and when the suction nozzle and the cover plate are fitted, the entire screen mesh part is located in the capsule insertion port 91. Thus, when inhaling the drug powder, under the action of negative pressure, the air flow can better pass through the screen mesh part to form an ideal flow direction, improving the inhalation efficiency of the drug powder.

[0144] In an exemplary embodiment, to further ensure the tight fit between the filter element and the cover plate, there are corresponding engaging parts between the filter element and the cover plate, so that the filter element can be snapped onto the cover plate. Thus, when the filter element is assembled at the bottom of the inhalation channel, the suction nozzle and the cover plate can be relatively fixed by means of the filter element.

[0145] In a possible implementation manner, the installation part of the filter element includes two second engaging parts located at the proximal end and extending downward, and the cover plate is provided with engaging holes corresponding to the two second engaging parts respectively to achieve the engagement between the nozzle and the cover plate. In an embodiment, the second engaging part has a stepped structure to engage with the engaging hole.

[0146] Please continue to refer to Figure 1c , two second engaging parts 313 are provided at the proximal end of the filter element 3, and the second engaging parts 313 are engaged with the two engaging holes at the proximal end of the cover plate. Please refer to Figure 13 , which shows a schematic diagram of the nozzle, filter element and cover plate in an embodiment of the present application. As shown in the figure, when the filter element is engaged at the bottom of the suction channel of the nozzle, the nozzle can be engaged with the cover plate 9 through the second engaging part on the filter element, so that the filter element fits more closely to the capsule insertion port of the cover plate, ensuring the air intake efficiency.

[0147] It should be noted that the stepped structure and the engaging hole in this embodiment are only examples rather than limitations of the engaging method between the filter element and the cover plate. In actual applications, the second engaging part can also be other structures that can be engaged with the engaging hole, which will not be elaborated here.

[0148] In an exemplary embodiment, a plurality of air holes are evenly distributed on the opposite surface of the cover plate to the filter element to form an air flow when a negative pressure is generated in the chamber, and the number of the air holes can be one or more. In some embodiments, the opposite surface of the cover plate to the filter element is the capsule insertion port, and the air holes can be evenly distributed on the capsule insertion port, or can be irregularly arranged at the capsule insertion port.

[0149] Please refer to Figure 14 and combine with Figure 13 , wherein, Figure 14 shows a schematic structural diagram of the cover plate in another embodiment of the present application. As Figure 14 shown, 3 air holes 96 are evenly distributed at the capsule insertion port of the cover plate. In a possible implementation manner, the diameter of the air holes is not greater than 1 mm. In an embodiment, the filter element is arranged at the bottom of the suction channel of the nozzle, the nozzle is located above the cover plate so that the filter element fits the capsule insertion port of the cover plate, and the cover plate is covered on the base. When a negative pressure is generated in the suction channel, the air flow enters the base from the first air inlet and the second air inlet respectively, and a part of the air flow will enter the capsule chamber, and a small part will pass through the air holes 96, as Figure 13As shown. In some embodiments, the air flow passing through the air holes 96 and the air entering the capsule chamber can help generate turbulence, so that the capsule vibrates and / or rotates in the capsule chamber, which is beneficial to the release of the powdered medicine in the capsule. In some embodiments, when the cover plate is provided with air holes 96, the air intake is about 10% different from that when there are no air holes on the cover plate, so as to facilitate generating an ideal air flow direction while ensuring the air flow rate.

[0150] Wherein, the cover plate and the capsule chamber can be manufactured separately and then connected and fitted together as a whole, or can be an integral molding structure.

[0151] In an exemplary embodiment, the chamber of the capsule chamber includes a main chamber. In order to keep the capsule in a vertical state in the main chamber so as to be punctured by the puncturing assembly, the diameter of the main chamber is larger than the transverse cross-sectional diameter of the capsule and smaller than the longitudinal cross-sectional diameter of the capsule. Please refer to Figure 11 , which shows a schematic structural diagram of the cover plate, the capsule chamber and the capsule in an embodiment of the present application. As shown, the transverse diameter D1 of the main chamber 421 is larger than the transverse cross-sectional diameter D3 of the capsule 8 so that the capsule 8 can enter the main chamber, and the transverse diameter D1 of the main chamber 421 is smaller than the longitudinal cross-sectional diameter D2 of the capsule 8 so that the capsule 8 remains in a vertical state in the main chamber 421. In a possible implementation manner, the ratio of the transverse diameter to the longitudinal diameter of the main chamber is 1:2 to 1:3. In some embodiments, to ensure the gas flow rate in the main chamber, the ratio of the cross-sectional area of the main chamber to the total area of the first air flow inlet and the second air flow inlet is 1:2 to 1:1.5.

[0152] It should be noted that in this embodiment, the size of the capsule is not limited, and the capsule can be a capsule of any size. In order to adapt to the capsule size, the diameter of the main chamber can also be configured to match the size of the capsule. The size of the capsule is usually related to the amount of medicine used. That is, when the amount of powder is large, the capsule size is also designed to be larger, and when the amount of powder is small, the capsule size is also designed to be smaller.

[0153] In one embodiment, considering the existing amount of powdered medicine used, such as tiotropium bromide, indacaterol, etc. mentioned above, the transverse cross-sectional diameter D3 of the capsule 8 is usually designed to be 5-6 mm, and the height, that is, the longitudinal cross-sectional diameter D2, is designed to be 15-16 mm. And, in some implementation manners, since the capsule is assembled by two upper and lower shells, please refer to Figure 12 , which shows a schematic structural diagram of the capsule in an embodiment of the present application. The outer shell of the capsule is assembled by an upper shell 8a and a lower shell 8b. The sum of the longitudinal cross-sectional diameters of the upper shell 8a and the lower shell 8b is usually designed to be 16-17 mm.

[0154] In an exemplary embodiment, please continue to refer to Figure 11 , a secondary chamber 422 communicating with the main chamber 421 is provided at the bottom of the chamber 42 of the capsule magazine. The secondary chamber 422 is used to provide an air inlet passage for the main chamber 421. The bottom end of the secondary chamber 422 has an air inlet. In order to enable the capsule magazine to communicate with the internal space of the base body after being engaged with the base body to form an air inlet passage, there is a gap between the air inlet at the bottom end of the secondary chamber and the bottom surface of the base. Also, in order to prevent the capsule from falling from the main chamber into the secondary chamber, the diameter D4 of the secondary chamber is smaller than the transverse cross-sectional diameter D3 of the capsule. In some embodiments, to ensure the air intake volume in the chamber, the ratio of the cross-sectional area of the chamber air inlet to the total area of the first air flow inlet and the second air flow inlet is 1:8 to 1:7.

[0155] In an exemplary embodiment, the chamber of the capsule magazine includes a mounting structure that cooperates with the piercing assembly, so that the piercing assembly remains connected to the capsule magazine in the non-use state and can move relative to the capsule magazine in the use state to pierce the capsule in the capsule magazine. The mounting structure includes a mounting plate, which can be an integral structure with the chamber. The mounting plate is provided with a slot for enabling the button member of the piercing assembly to move relative to the capsule magazine without detaching from the capsule magazine, and a tube portion for restricting the piercing direction of the needle of the piercing assembly. In some embodiments, in order to apply a force to the piercing assembly during use so that it can automatically return to the initial position after piercing the capsule, the piercing assembly further includes a reset mechanism. Examples of the reset mechanism include, but are not limited to, elastic elements such as springs; and, a abutting portion is provided at a position corresponding to the reset mechanism on the mounting plate to play a role in restricting the position of the reset mechanism to ensure its normal operation. In some embodiments, a mounting block for mounting the reset mechanism may also be provided on the button member to achieve a more secure connection. Among them, the setting positions of the slot, the abutting portion, and the tube portion can be determined according to the structure of the piercing assembly. For example, when the piercing assembly is movably connected to the mounting plate through the left and right sides of the button member, the piercing assembly cooperates with two needles arranged up and down to pierce the capsule in the capsule magazine, and the reset mechanism is arranged between the two needles, the slot can be correspondingly opened on the symmetric left and right sides of the mounting plate, the abutting portion can be located between the symmetric slots, and the two tube portions corresponding to the two needles can be respectively located on the upper and lower sides of the abutting portion.

[0156] In one embodiment, the number of needles in the piercing assembly can be one or more. The proximal ends of the needles are cooperatively connected with the button member, for example, by interference fit connection, etc. The position and number of the tube portions on the mounting plate correspond to the position and number of the needles. After the piercing assembly is installed on the capsule magazine, the needles can be inserted into the corresponding tube portions on the mounting plate, that is, the distal sides of the needles are located in the corresponding tube portions. When a force is applied to the button member, the needles can move along the tube portions to pierce the capsule located in the chamber after extending into the chamber.

[0157] The puncturing needle is a component for puncturing the capsule. The puncturing needle does not necessarily have a slender structure and can also be a thin sheet-like structure. For example, the puncturing needle can also be designed to be flat and similar to a blade structure. Correspondingly, the tube portion on the mounting plate can also be adjusted to a flat pipeline structure so that the blade-like puncturing needle can move within its pipeline. In this embodiment, when the puncturing needle punctures the capsule, it will cut a relatively large opening in the capsule in a cross-cutting manner or directly cut the capsule into two halves or multiple pieces.

[0158] In a possible implementation manner, to ensure that each puncturing needle can play a role and improve the drug escape efficiency, the distance between the two puncturing needles that are farthest apart from each other among the puncturing needles should be less than the height of the capsule and greater than half of the height of the capsule. For example, when there are two puncturing needles, the distance between the two puncturing needles should be less than the height of the capsule and greater than half of the height of the capsule. For example, when the puncturing needle punctures the capsule, the position where the capsule is broken is exactly at the transition position between the main body part and the top part at both ends of the capsule. In this embodiment, the distance between the holes formed on the capsule after the puncturing needle punctures the capsule is 3 / 5 to 4 / 5 of the height of the assembled capsule.

[0159] The arrangement mode of each puncturing needle can be configured according to the placement direction of the capsule and the number of puncturing needles. For example, when there is one puncturing needle, it can be set at the position corresponding to the center of the capsule; when there are two puncturing needles and the capsule is placed vertically, the two puncturing needles can be arranged vertically; when there are two puncturing needles and the capsule is placed horizontally, the two puncturing needles can be arranged horizontally; when there are three or more puncturing needles, the puncturing needles can be on the same straight line or not on the same straight line. It should be understood that the above settings of the puncturing needles are only examples and not limitations, and can be adjusted according to specific requirements in actual applications, which will not be elaborated here.

[0160] It should be noted that in the above embodiment, the capsule bin is designed as a vertical structure so that the capsule is placed in the capsule bin in a vertical state. In other possible implementation manners, the capsule bin can also be designed as a horizontal structure so that the capsule is placed in the capsule bin in a horizontal state. Correspondingly, the puncturing needles in the puncturing assembly and the tube portion on the mounting plate are both configured to be arranged horizontally to cooperate with the placement direction of the capsule to puncture the capsule.

[0161] In an exemplary embodiment, please refer to Figure 15, which shows a schematic diagram of the structure of the lancet in the present application in one embodiment. As shown in the figure, in order to facilitate the lancet to pierce the capsule and avoid the generation of capsule debris as much as possible, the needle tip of the lancet 52 has a bevel, and the position of the needle tip is eccentrically designed. The tip of the lancet is formed by three oblique planes intersecting at the same point, and the tip does not coincide with the extension line of the axis of the lancet, that is, the tip of the needle tip is not in a straight line with the axis position of the lancet. When piercing the capsule shell, the fragments at the capsule break are not easy to fall off the capsule, which fundamentally avoids the generation of capsule debris to ensure the safety and comfort of the inhalation process. At the same time, this structure can also effectively release the drug powder during the inhalation process. In some embodiments, the diameter of the lancet can be designed to be 1mm to 2mm.

[0162] In one embodiment, in order to facilitate the active connection of the piercing assembly to the mounting plate, the button member of the piercing assembly includes a pressing portion and a movable connecting portion, wherein the pressing portion and the movable connecting portion are an integrated structure, and the distal end of the movable connecting portion has a limiting portion that cooperates with the card slot, so that the piercing assembly can move relative to the capsule chamber but not separate from the mounting plate.

[0163] For possible implementations, see Figure 16 , which is a schematic diagram of the structure of the button member in one embodiment of the present application, such as Figure 16 As shown, the button member 51 includes an integrally formed pressing portion 510 and a movable connecting portion. In this embodiment, the movable connecting portion includes extension arms 511 extending distally on both sides of the button member 51. The distal end of the extension arm 511 is provided with an outwardly protruding hook portion 512 as a limiting portion, and the hook portion and the extension arm are an integral structure.

[0164] Correspondingly, see Figure 17 , which is a schematic diagram of the structure of the installation structure in the present application in one embodiment. As shown in the figure, two slots 441 are provided on the installation plate 44. The positions of the two slots 441 correspond to the positions of the extension arms 511, and the width of the slots 441 is slightly larger than the width of the extension arms 511, so that the extension arms 511 can slide in the slots. At the same time, the width of the hook portion 512 and the extension arm 511 added together is larger than the width of the slots 441, so that the extension arms will not fall off the installation plate when sliding in the slots 441.

[0165] In some cases, see Figure 18a , Figure 18b , which is a schematic diagram of the structure of the button member in another embodiment of the present application, wherein: Figure 18b for Figure 18a A magnified view of the G section from another perspective. Figure 18bAs shown, to further facilitate the assembly of the piercing component to the mounting plate 44, the hook portion 512 of the button member 51 has an inclined surface s, and the distance between the inclined surface s and the extension arm 511 increases from the distal side to the proximal side. Please refer to Figure 17 and in combination with Figure 18b , the card slot has a shape corresponding to the hook portion on the side to provide a deformation space for the extension arm. The minimum width h at the inclined surface e1 is less than the width h of the card slot 441 g , and the maximum width h at the inclined surface e2 is approximately equal to the width h of the card slot 441 g . Here, as shown in Figure 18b , the minimum width h at the inclined surface e1 includes the width of the sum of the distal side of the hook and the distal side of the extension arm. The maximum width h at the inclined surface e2 includes the width of the sum of the proximal side of the hook and the proximal side of the extension arm. Based on this structural design, during installation, the distal side of the extension arm 511 is aligned with the card slot 441 on the mounting plate 44. Since the minimum width h at the inclined surface e1 is less than the width h of the card slot 441 g , the extension arm 511 can pass through the card slot. As the width at the inclined surface increases, the inclined surface gradually adheres to the edge of the card slot 441. After applying force continuously, the card slot 441 will exert pressure on the inclined surface, and the extension arm will produce a slight elastic deformation due to its own material properties to continue moving distally. Finally, when the entire hook portion 512 passes through the card slot 441, the extension arm returns to its initial state and limits the piercing component through the hook portion 512, so that the piercing component can move relative to the capsule chamber but does not detach from the mounting plate.

[0166] It should be noted that the structure of the limiting portion in this embodiment is only an example and not a limitation. In actual applications, the limiting portion can also be other structures, as long as it can enable the button member to pass through the mounting plate and be limited thereon. For example Figure 18a 、 18b , the hook portion in

[0167] can also be replaced with multiple small hooks distributed on the distal side of the extension arm as the limiting portion, etc. Figure 21 In some cases, since the needle is located inside the tube portion on the mounting plate during use, the position of the needle relative to the capsule in the capsule chamber cannot be clearly seen during the use state, and it is impossible to directly determine whether the capsule has been fully punctured. Please refer to

[0168] In one embodiment, please refer to Figure 19 and in combination with Figure 17 , wherein Figure 19 it shows a schematic structural view of the piercing assembly in the present application in yet another embodiment. Please first refer to Figure 19 , the number of the lancets 52 is two and they are arranged vertically. Both of the two lancets 52 are located between the front and rear extending arms 511 and are connected to the button member 51 by interference fit at the proximal side. Please refer to Figure 17 , on the mounting plate 44 of the capsule chamber, two tube parts 443 are provided corresponding to the two lancets. Therefore, the two tube parts 443 are also arranged vertically on the mounting plate 44, and the tube parts 443 communicate with the chamber 42 of the capsule chamber 4. After the piercing assembly 5 is installed on the capsule chamber, the lancets are inserted into the tube parts 443, that is, the distal sides of the lancets 52 are located in the two tube parts 443. When a force is applied to the button member 51, the lancets 52 can move along the tube parts 443 to pierce the capsule located in the chamber 42 after extending into the chamber. The insertion means that the diameter of the lancet is smaller than the diameter of the tube part, so that it can pass through the hollow part of the tube part. And for facilitating the movement of the lancet along the tube part, a part of the lancet, for example, the distal end of the lancet, can be located in the tube part in the initial state (that is, the state without applying a force to the button member).

[0169] In order to enable the piercing assembly to automatically return to the initial position after applying a force to pierce the capsule during use, the piercing assembly further includes a reset mechanism 53. The reset mechanism 53 includes, by way of example and without limitation, a spring, etc. And, a abutting part 442 is provided at the position corresponding to the reset mechanism 53 on the mounting plate 44 to play a role in restricting the position of the reset mechanism to ensure its normal operation. Here, the abutting part 422 can be a mounting seat for fixing the reset mechanism 53. For example, when the reset mechanism is a spring, the abutting part 422 can be a spring mounting seat protruding proximally to sleeved the distal side of the spring on the mounting seat. Here, considering the space utilization efficiency of the mounting plate, the abutting part 442 is arranged at the center of the mounting plate, that is, between the left and right card slots 441 and between the upper and lower tube parts 443. Please refer to Figure 20 , it shows a schematic structural view of the button member in the present application in yet another embodiment. As shown in the figure, a mounting block 513 is provided at the position corresponding to the reset mechanism on the button member 51. Here, the mounting block 513 is a protrusion in an approximate "cross" shape to mount the reset mechanism thereon. Of course, in other embodiments, the reset mechanism can also be arranged at other positions as long as the button member can be reset after being stressed. The structure of the abutting part and / or the mounting block can also be designed according to actual needs and is not limited to the outward protruding structure. For example, the abutting part and / or the mounting block can also be a recessed structure, such as a groove, etc., to mount the reset mechanism therein.

[0170] In an exemplary embodiment, please continue to refer toFigure 9 As shown in the figure, an opening 613 is provided at the proximal end of the base. After the capsule chamber is assembled into the base, the opening 613 provides an installation space and a movement space for the piercing assembly, enabling the piercing assembly to move along the capsule chamber under a stressed state.

[0171] In an exemplary embodiment, to facilitate observing the state of the capsule in the capsule chamber during operation, the base further includes a transparent window, which is installed on the base body. At the same time, the chamber of the capsule chamber is also made of a transparent material, so that the state of the capsule in the chamber and the state of breaking the wall of the capsule during piercing can be observed through the transparent window and the transparent chamber during use.

[0172] Among them, the position of the transparent window provided on the base can be designed according to actual needs. For example, the transparent window can be provided on the front and rear sides of the base, or the transparent window can also be located at the distal end of the base and extend to the front and rear sides of the base, as long as the state of the capsule in the capsule chamber can be clearly seen through the window.

[0173] In an embodiment, please refer to Figure 22 which shows a schematic structural diagram of the base in an embodiment of the present application. As shown in the figure, the transparent window 63 is located above one side at the distal end of the base 61, and both sides of the transparent window extend to the front and rear sides of the base body respectively, that is, the upper part at the distal side, the upper part at the distal end of the front side, and the upper part at the distal end of the rear side of the base body are all transparent, so as to facilitate observing the state of the capsule in the capsule chamber. Among them, the transparent window can be integrally formed on the base body, or can be separate and installed on the base body. In other embodiments, the base can also be entirely made of a transparent material.

[0174] In an exemplary embodiment, a flow limiting plate is further provided in the base. Air flow guiding holes are formed on the flow limiting plate to limit the size of the air flow and control the intake direction of the air flow. In a possible embodiment, since a movement space for the button member needs to be provided on the proximal side of the base, setting the flow limiting plate on the side closer to the distal end inside the base can simplify the structural design. The number of the air flow guiding holes can be configured as one or more according to actual needs. Similarly, the shape and the opening position of the air flow guiding holes can also be designed according to parameters such as the desired air flow direction and flow rate.

[0175] In an embodiment, please refer to Figure 25, which shows a schematic structural view of the base in another embodiment of the present application. As shown in the figure, a current-limiting plate 66 is provided in the base body of the base 6, and two air flow guiding holes are symmetrically formed on the current-limiting plate. When a negative pressure is generated in the suction channel, the air flow entering from the second air inlet channel enters the capsule chamber after being controlled by the air flow guiding holes. Here, the air flow guiding holes are long and narrow openings, so that the air flow in the second air inlet channel converges at the two air flow guiding holes. In a possible implementation manner, the area of each air flow guiding hole can be determined according to parameters such as the areas of the first air inlet and the second air inlet or the total air intake volume. In one embodiment, the area of each air flow guiding hole can be 20-35 mm 2 , such as 20 mm 2 , 21 mm 2 , 22 mm 2 , 23 mm 2 , 24 mm 2 , 25 mm 2 , 26 mm 2 , 27 mm 2 , 28 mm 2 , 29 mm 2 , 30 mm 2 , 31 mm 2 , 32 mm 2 , 33 mm 2 , 34 mm 2 , 35 mm 2 and so on.

[0176] In an exemplary embodiment, please continue to refer to Figure 1b , which shows a schematic structural view of the inhalation device in yet another embodiment of the present application. As shown in the figure, the inhalation device includes a cover body 1, a mouthpiece 2, a filter element 3, a cover plate 9, a capsule chamber 4, a piercing assembly 5, and a base 6. Among them, the cover body 1 and the base 6 are coaxially hinged at the far side through a second hinge portion (19, 69b), and the mouthpiece 2, the cover plate 9, and the base 6 are coaxially hinged at the far side through a first hinge portion (29, 99, 69a).

[0177] Above the nozzle body of the nozzle 2, there is a suction port adapted to the human mouth and an operation part for easy operation. The suction port is used to cooperate with the human mouth so that the user can inhale the powdered medicine into the respiratory tract through the nozzle. The proximal end of the operation part has a concave structure for operation during use, facilitating the approach or separation of the nozzle body and the cover plate and maintaining the cleanliness of the suction port. The bottom of the inhalation channel of the nozzle 2 is in a tubular structure, and the filter element 3 is sleeved on this tubular structure. The filter element 3 includes a mounting part for mounting on the inhalation channel and a screen part for filtering. The mounting part of the filter element 3 is matched with a rib around the outer surface of the lower part of the inhalation channel through a groove on the inner surface, thereby clamping the filter element 3 at the bottom of the inhalation channel. The screen part of the filter element is made of stainless steel and formed by stamping to form a circular arc convex surface at the center and a rib at the periphery of the circular arc convex surface. The diameter of the mesh holes of the screen part is less than or equal to 0.6 mm to 1 mm, and the wire diameter of the screen part is 0.1 mm to 0.5 mm. The screen part and the mounting part are integrally welded by ultrasonic waves, and thus a rib is formed on the surface of the mounting part.

[0178] The cover plate 9 is located below the nozzle and is provided with a capsule insertion port corresponding to the filter element. Two first air inlets 92 are provided on the near side of the cover plate 9, and two second air inlets 93 are provided on the far side of the cover plate. When the cover plate is clamped on the base, a first air intake channel from the first air inlet to the chamber and a second air intake channel from the second air inlet to the chamber are formed. The total area of the first air inlet and the second air inlet is 74 mm 2 . The mounting part of the filter element includes two second clamping parts located at the proximal end and extending downward. The cover plate also has clamping holes corresponding to the two second clamping parts respectively. Thus, when the filter element is installed on the inhalation channel of the nozzle, the nozzle and the cover plate are clamped. The opposite surface of the filter element and the capsule insertion port of the cover plate has end faces with matching shapes, so that in the clamped state of the nozzle and the cover plate, the filter element can be pressed on the capsule insertion port and fit tightly to avoid air leakage. Three air holes are evenly distributed on the cover plate at the opposite surface of the filter element for forming an air flow when negative pressure is generated in the chamber. Here, although there is a rib on the mounting part, a small amount of air flow can still pass through the gap between the rib and the cover plate during use.

[0179] The capsule compartment 4 is located below the cover plate 9, and includes a chamber 42, wherein the chamber 42 is further divided into a main chamber and a sub-chamber. The capsule can be placed in the main chamber through the capsule placement port on the cover plate. Since the diameter of the main chamber is larger than the transverse cross-sectional diameter of the capsule and smaller than the longitudinal cross-sectional diameter of the capsule, and the diameter of the sub-chamber is smaller than the transverse cross-sectional diameter of the capsule, the capsule is kept in a vertical state in the main chamber to facilitate being pierced by the piercing assembly. The upper part of the sub-chamber is connected to the main chamber, and the lower part also has an opening, and there is a gap between the sub-chamber and the bottom of the base to allow external airflow to enter the capsule compartment.

[0180] The piercing assembly 5 maintains a positional relationship with the capsule compartment 4 through the mounting plate. The piercing assembly 5 includes a button member, two puncture needles and a reset mechanism. The button member includes a pressing portion and movable connection portions located on both sides of the distal end of the pressing portion. A card slot is correspondingly provided at a position corresponding to the movable connection portion on the mounting plate. The limiting portion on the movable connection portion can limit the button member in the card slot so that the button member can move along the card slot but will not be separated from the card slot. The reset mechanism is located between the movable connection portions on both sides. A supporting portion is provided at a position corresponding to the reset mechanism on the mounting plate. One side of the reset mechanism is connected to the button member in cooperation with the button member, and the other side is installed on the supporting portion to help the button member return to its initial position after pressure is applied to the button member. The proximal ends of the two puncture needles are respectively fixed on the button member and are arranged up and down. Relatively, tube portions are respectively provided at positions corresponding to the two puncture needles on the mounting plate, so that after the puncture assembly is installed on the mounting plate of the capsule compartment, the two puncture needles are respectively located in their respective corresponding tube portions. Since the tube portions are connected to the main chamber, when pressure is applied to the button member, the button member can drive the puncture needles through the tube portions to the main chamber to puncture the capsule.

[0181] The tip of the puncture needle is formed by three oblique planes intersecting at the same point, and the tip does not coincide with the extension line of the axis of the puncture needle. The diameter of the puncture needle is 1 mm to 2 mm, so that the puncture needle can puncture the capsule and avoid the generation of capsule debris as much as possible. The distal end of the puncture needle and the distal end of the movable connection part are located on the same vertical line, so that when the button is assembled in the capsule compartment, when the puncture assembly is pressed, the user can sense the distal position of the puncture needle through the distal position of the movable connection part of the button.

[0182] The base 6 includes a base body 61, the interior of the base body 61 is a hollow structure for accommodating the chamber 42 of the capsule compartment, and an opening is provided on the proximal side of the base body 61, so that after the capsule compartment is assembled into the base, the opening 613 provides a movement space for the piercing assembly, so that the piercing assembly can move along the capsule compartment under the application of force. The lower surfaces of the front and rear sides of the cover plate have protrusions; the top of the inner side wall of the base is formed with a support portion corresponding to the protrusion, which is used to achieve sealing and mutual support with the front and rear sides of the base when the cover plate is covered on the base. The protrusion is provided with a third clamping portion, and the upper side edge of the base has a fourth clamping portion corresponding to the third clamping portion, so as to clamp the base with the cover plate; and the cover plate also has a fifth clamping portion on both sides, and the upper side edge of the base has a sixth clamping portion corresponding to the fifth clamping portion, so as to strengthen the clamping between the base and the cover plate. The base is also provided with a third air inlet at the far side. When the cover is closed on the base, the third air inlet is connected to the second air inlet. When negative pressure is generated in the inhalation channel, a second air inlet channel from the third air inlet and the second air inlet to the chamber is formed, thereby increasing the air intake. The base has a flow restriction plate with airflow guide holes at the far end. The number of airflow guide holes is two, which are symmetrically provided on the flow restriction plate. The area of each airflow guide hole is 28 mm. 2 , used to limit the airflow size and control the air intake direction of the airflow.

[0183] The base also includes a transparent window installed on the base body. The chamber of the capsule bin has a transparent wall. The transparent window is located at the far end of the base and extends to the front and rear sides of the base for observing the state of the capsules in the capsule bin through the base when in use.

[0184] The two sides of the inner part of the cover body are respectively provided with first engaging parts. When the cover body is closed, the two first engaging parts respectively pass through the two first air flow inlets on the front side of the cover plate and engage with the two side edges of the base body. The upper distal end of the button member has an inclined surface. When the button member is pressed, it moves toward the capsule compartment so that the inclined surface contacts the first engaging part and the first engaging part is pushed upward to release the engagement between the cover body and the base.

[0185] Here, to ensure the suction efficiency, the area of the first air flow inlet is 9 mm 2 , the orifice area of the tubular structure is 18.9mm 2 The total mesh area of the screen is 30mm 2 , the cross-sectional area of the main chamber is 47.2mm 2 , the cross-sectional area of the chamber air inlet is 10.4mm 2 .

[0186] In use, first open the cover 1 and the nozzle 2, place the capsule into the main chamber through the capsule insertion port 91 on the cover plate 9, then close the nozzle 2 and the cover 1 and press the button member. The button member drives the puncturing needle to enter the main chamber along the tube portion to puncture the capsule. The operator can sense the distal position of the puncturing needle through the distal position of the movable connection portion of the button member. When the operator withdraws the force applied to the button member, the reset mechanism resets the button member to the initial position.

[0187] Then, the user opens the cover and inhales with the mouth around the upper part of the nozzle. Please refer to Figure 26 , which shows a schematic diagram of the air flow direction of the inhalation device in this application in an embodiment. As shown in the figure, under the negative pressure generated in the nozzle 2, the external air flow enters the main chamber 421 through the bottom of the auxiliary chamber 422 via the first air intake channel and the second air intake channel. Moreover, the air holes provided at the capsule insertion port of the cover plate will generate an air flow to help the capsule vibrate and rotate to facilitate the release of the drug powder in the capsule. Due to the structural design of the screen portion, an air flow conducive to the escape of the powder is generated in the main chamber. The powder enters the inhalation channel of the nozzle 2 via the screen portion, while the capsule debris is blocked outside the screen portion. The powder in the inhalation channel is then inhaled into the user's body along with the trend.

[0188] Finally, open the nozzle to clean the capsule shell and debris in the capsule chamber, and / or after washing, drying, cover the nozzle and the cover for subsequent use.

[0189] The inhalation device in this application adopts a bilateral air intake design, and through multiple designs such as the structure of the screen portion, the air holes at the capsule insertion port, and the flow limiting plate, an ideal air flow direction is generated in the use state of the inhalation device to help the capsules in the capsule chamber vibrate and / or rotate to release the drug powder, ensuring the inhalation efficiency. Moreover, the inhalation device in this application can achieve button-opening of the cover through the cooperation between the button member and the cover and the base, which is convenient to use. In addition, multiple designs such as the double-axis connection of the inhalation device and the support structure of the cooperation between the cover plate and the base can ensure the service life of the product; the concave structure of the operation portion of the nozzle can ensure the hygiene and cleanliness during use, and the positional relationship between the puncturing needle and the movable connection portion is convenient for sensing the puncturing position, which is convenient to operate and conforms to the ergonomic design.

[0190] The above embodiments are only illustrative of the principles and effects of this application, rather than limiting this application. Any person familiar with this technology can modify or change the above embodiments without departing from the spirit and scope of this application. Therefore, all equivalent modifications or changes completed by those with ordinary knowledge in the technical field without departing from the spirit and technical idea disclosed in this application should still be covered by the claims of this application.

Claims

1. An inhalation device, characterized in that, Comprising: A nozzle, including a nozzle body and an inhalation channel formed within the nozzle body; A filter element, disposed at the bottom end of the inhalation channel, for blocking capsule debris generated after the capsule is punctured; A cover plate, disposed below the nozzle and provided with a capsule insertion port corresponding to and combined with the filter element, a first air inlet and a second air inlet are respectively provided on the near side and the far side of the cover plate; a plurality of air holes are evenly distributed on the cover plate at the opposite surface of the filter element, for helping to generate turbulence in the chamber when a negative pressure is generated in the chamber so that the capsule vibrates and / or rotates; A capsule chamber, located below the cover plate and having a chamber for accommodating the capsule in a use state, the chamber communicates with the capsule insertion port of the cover plate, the chamber of the capsule chamber includes a main chamber and an auxiliary chamber communicating with the main chamber, the bottom end of the auxiliary chamber has a chamber air inlet, the ratio of the cross-sectional area of the main chamber to the total area of the first air inlet and the second air inlet is 1:2 to 1:1.5, and the ratio of the cross-sectional area of the chamber air inlet to the total area of the first air inlet and the second air inlet is 1:8 to 1:7; A piercing assembly, including a button member and a piercing needle movably disposed on one side of the capsule chamber, the button member moves towards the capsule chamber in a pressed state to drive the piercing needle to puncture the capsule in the capsule chamber; A base, including a seat body for accommodating the capsule chamber and part of the piercing assembly, in a state where the cover plate is covered on the base, a first air inlet passage from the first air inlet to the chamber and a second air inlet passage from the second air inlet to the chamber are formed; a flow limiting plate with a long and narrow air flow guiding hole is provided on the inner side of the base near the distal end, for restricting the air flow entering from the second air inlet passage to enter the capsule chamber after passing through the air flow guiding hole; A cover body, covering the nozzle in a state of being engaged with the base; Wherein, when a negative pressure is generated in the chamber, the air flows in the first air inlet passage and the second air inlet passage converge at the bottom end of the chamber and enter the chamber, so that the punctured capsule in the chamber vibrates and / or rotates under an ideal air flow direction to release the internal drug powder, and enters the inhalation channel through the capsule insertion port and the filter element.

2. The inhalation device according to claim 1, characterized in that, The distal ends of the base, the cover plate and the nozzle are coaxially connected through a first hinge portion, the cover body and the distal end of the base are coaxially connected through a second hinge portion, and the first hinge portion and the second hinge portion are not coaxial.

3. The inhalation device according to claim 1, characterized in that, First engaging portions are provided on both sides of the cover body, passing through the first air inlet, for realizing engagement with the edges on both sides of the seat body of the base.

4. The inhalation device according to claim 1, characterized in that, The tip of the piercing needle is formed by the intersection of three oblique planes at the same point, and the extension line of the tip and the axis line of the piercing needle do not coincide.

5. The inhalation device according to claim 1 or 4, characterized in that, The diameter of the piercing needle is 1 mm to 2 mm.

6. The inhalation device according to claim 1, characterized in that, The number of the piercing needles is two and they are arranged vertically, the distance between the two vertically arranged piercing needles is less than the height of the capsule and greater than half of the height of the capsule.

7. The inhalation device according to claim 1, characterized in that, The nozzle body includes: An operation portion, located on the near side of the nozzle body, for being operated during use to make the nozzle body approach or separate from the cover plate; The suction port, integrally formed with the operation part, has the suction channel and an outer contour adapted to the human mouth.

8. The inhalation device according to claim 7, characterized in that, The proximal end of the operation part has a concave structure.

9. The inhalation device according to claim 8, characterized in that, There is an operation mark at the concave structure.

10. The inhalation device according to claim 1, characterized in that, The ratio of the cross-sectional area of the suction channel to the total area of the first air inlet and the second air inlet is 1:4.5 to 1:3.

5.

11. The inhalation device according to claim 1, characterized in that, The filter element includes a mounting part for mounting in the suction channel and a screen part for filtering.

12. The inhalation device according to claim 11, characterized in that, The bottom of the suction channel is in a tubular structure, and the outer surface of the bottom end of the tubular structure and the inner surface of the mounting part of the filter element have corresponding mounting structures to arrange the filter element at the bottom end of the tubular structure.

13. The inhalation device according to claim 11, characterized in that, The screen part includes a circular arc convex surface at the center and a retaining edge along the circumference of the circular arc convex surface.

14. The inhalation device according to claim 11, characterized in that, The mesh diameter of the screen part is less than or equal to 0.6mm.

15. The inhalation device according to claim 11, characterized in that, The mesh diameter of the screen part is less than or equal to 0.7mm.

16. The inhalation device according to claim 11, characterized in that, The mesh diameter of the screen part is less than or equal to 0.8mm.

17. The inhalation device according to claim 11, characterized in that, The mesh diameter of the screen part is less than or equal to 0.9mm.

18. The inhalation device according to claim 11, characterized in that, The mesh diameter of the screen part is less than or equal to 1mm.

19. The inhalation device according to claim 11, characterized in that, The wire diameter of the screen part is 0.1mm to 0.5mm.

20. The inhalation device according to claim 11, characterized in that, The ratio of the total area of the mesh of the screen part to the total area of the first air inlet and the second air inlet is 1:3 to 1:

2.

21. The inhalation device according to claim 11, characterized in that, The screen part is made of stainless steel.

22. The inhalation device according to claim 11, characterized in that, The screen part and the mounting part are integrally welded by ultrasonic waves and thus a raised ring is formed on the surface of the mounting part.

23. The inhalation device according to claim 1 or 11, characterized in that, The opposite surfaces of the filter element and the cover plate have end faces with matching shapes so that the filter element and the cover plate are closely fitted.

24. The inhalation device according to claim 11, characterized in that, The mounting part includes two second engaging parts located at the proximal end and extending downward, and the cover plate has engaging holes corresponding to the two second engaging parts respectively to realize the engagement of the nozzle and the cover plate.

25. The inhalation device according to claim 1, characterized in that, There are raised parts on the lower surfaces of the front and rear sides of the cover plate; a support part corresponding to the raised parts is formed at the top of the inner side wall of the base to realize sealing and mutual support with the front and rear sides of the base when the cover plate is covered on the base.

26. The inhalation device according to claim 25, characterized in that, There is a third engaging part on the raised part, and a fourth engaging part corresponding to the third engaging part is provided on the upper side edge of the base.

27. The inhalation device according to claim 1 or 25 or 26, characterized in that, There are fifth engaging parts on both sides of the cover plate respectively, and a sixth engaging part corresponding to the fifth engaging part is provided on the upper side edge of the base.

28. The inhalation device according to claim 1, characterized in that, The number of the first air inlets is two, which are respectively located at the front and rear sides of the proximal end of the cover plate.

29. The inhalation device according to claim 28, characterized in that, The areas of the first air flow inlets are each 3.5 to 15 mm 2 .

30. The inhalation device according to claim 1, characterized in that, The number of the second air inlets is two, which are opened on both sides of the distal end of the cover plate.

31. The inhalation device according to claim 30, characterized in that, A third air inlet is also opened on the far side of the base. In the state where the cover plate is combined with the base, the third air inlet is communicated with the second air inlet.

32. The inhalation device according to claim 1, characterized in that, The number of the second air inlets is one, which is opened at the distal end of the cover plate.

33. The inhalation device according to claim 1, characterized in that, The cover plate and the capsule chamber are integrally formed.

34. The inhalation device according to claim 1, characterized in that, The transverse diameter of the main chamber is larger than the transverse cross-sectional diameter of the capsule and smaller than the longitudinal cross-sectional diameter of the capsule.

35. The inhalation device according to claim 34, characterized in that, There is a gap between the chamber air inlet and the bottom surface of the base, and the diameter of the sub-chamber is smaller than the transverse cross-sectional diameter of the capsule.

36. The inhalation device according to claim 1, characterized in that, The chamber of the capsule compartment includes an installation structure for cooperating with the piercing assembly so that the piercing assembly uses its piercing needle to pierce the capsule in the capsule compartment during the movement relative to the capsule compartment.

37. The inhalation device according to claim 36, characterized in that, The installation structure includes: A mounting plate with symmetrically arranged card slots; A abutting portion formed on the mounting plate and located between the symmetric card slots; Two tube portions formed on the mounting plate and respectively located on the upper and lower sides of the abutting portion, communicating with the chamber, for restricting the piercing direction of the piercing needle.

38. The inhalation device according to claim 37, characterized in that, The piercing assembly further includes a reset mechanism located between the button member and the abutting portion, for being compressed when the button member moves towards the capsule compartment to provide a reset force to return the piercing needle and the button member to the initial position.

39. The inhalation device according to claim 38, characterized in that, The button member is provided with a mounting block for mounting the reset mechanism.

40. The inhalation device according to claim 37, characterized in that, The piercing needle is inserted into the tube portion, and the proximal end of the piercing needle is cooperatively connected with the button member.

41. The inhalation device according to claim 37, characterized in that, The button member includes a pressing portion and a movable connection portion integrally formed with the pressing portion, and the distal end of the movable connection portion has a limiting portion for cooperating with the card slot.

42. The inhalation device according to claim 41, characterized in that, The distal ends of the piercing needle and the movable connection portion are on the same vertical line.

43. The inhalation device according to claim 1, characterized in that, The proximal end of the base is provided with an opening to provide a movement space for the piercing assembly.

44. The inhalation device according to claim 1, characterized in that The base further includes a transparent viewing window mounted on the seat body, and the chamber of the capsule compartment has a transparent wall surface for observing the state of the capsule in the capsule compartment through the base in the use state.

45. The inhalation device according to claim 44, characterized in that, The transparent viewing window is located at the distal end of the base and extends to the front and rear sides of the base.

46. The inhalation device according to claim 1, characterized in that, The number of the air flow guiding holes is two, which are symmetrically arranged on the current limiting plate, and the area of each air flow guiding hole is 20-35 mm 2 .

47. The inhalation device according to claim 1, characterized in that, The total area of the first air inlet and the second air inlet is 50 to 100 mm 2 .

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