A blood analyzer and a detection method thereof

Abstract

The application discloses a blood analyzer and a detection method thereof. The blood analyzer comprises a mode selection module, a control module, a sampling assembly and a reaction assembly. The sampling assembly is used for distributing a collected blood sample to the reaction assembly. The reaction assembly is used for detecting the blood sample. The mode selection module is used for selecting one sampling mode from multiple sampling modes of the blood analyzer. The multiple sampling modes comprise an automatic sampling mode and an open sampling mode. When the mode selection module switches the automatic sampling mode to the open sampling mode, the control module controls the sampling assembly and / or the reaction assembly to be cleaned. In this way, the blood analyzer can be cleaned, pollution accumulation of the blood analyzer can be avoided, and the detection accuracy of the blood analyzer can be improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of blood detection, in particular to a blood analyzer and a detection method thereof. BACKGROUND

[0002] With the development of academic research and clinical examination, the blood analyzer has high practical value in blood routine detection or / and specific protein detection on blood samples, and can greatly help patients in the detection and treatment of infection types.

[0003] The existing blood analyzer continuously detects multiple blood samples, resulting in cumulative pollution, so that the detection accuracy of the blood analyzer is low. SUMMARY

[0004] To solve the above problems, the present application provides a blood analyzer and a detection method thereof, and a control module controls the sampling assembly and / or the reaction assembly to be cleaned, so as to improve the detection accuracy of the blood analyzer.

[0005] One of the technical solutions adopted by the present application is to provide a blood analyzer, which comprises a mode selection module, a control module, a sampling assembly and a reaction assembly, the sampling assembly is used to distribute the collected blood sample to the reaction assembly, the reaction assembly is used to detect the blood sample, the mode selection module is used to select one of multiple sampling modes of the blood analyzer, and the multiple sampling modes include an automatic sampling mode and an open sampling mode.

[0006] When the mode selection module switches the automatic sampling mode to the open sampling mode, the control module controls the sampling assembly and / or the reaction assembly to be cleaned.

[0007] The control module obtains the sample amount of the blood sample in the automatic sampling mode; when the mode selection module switches the automatic sampling mode to the open sampling mode, and the sample amount reaches a preset threshold, the control module uses a first cleaning mode to clean the sampling assembly and / or the reaction assembly.

[0008] When the mode selection module switches the automatic sampling mode to the open sampling mode, and the sample amount does not reach the preset threshold, the control module uses a second cleaning mode to clean the sampling assembly and / or the reaction assembly, and the cleaning strength of the second cleaning mode is less than that of the first cleaning mode.

[0009] The reaction assembly comprises a WBC reaction pool and an RBC reaction pool, and when the control module adopts the first cleaning mode to clean the reaction assembly, the geminoid hole of the WBC reaction pool and / or the geminoid hole of the RBC reaction pool is at least once burnt and back-flushed.

[0010] The sampling assembly comprises a sampling needle, the control module cleans the sampling needle through the sampling assembly, and controls the sampling needle to suck the isolated bubbles.

[0011] The blood analyzer is provided with a specific protein single detection mode and a detection mode containing routine blood detection, when the mode selection module switches the specific protein single detection mode to the detection mode containing routine blood detection, the control module adopts the first cleaning mode to clean the WBC reaction pool.

[0012] When the mode selection module selects the automatic sampling mode and the specific protein single detection mode, the control module judges that the detection times of specific proteins are an integer multiple of the preset times, and adopts the first cleaning mode to clean the WBC reaction pool and / or the RBC reaction pool.

[0013] Another technical scheme adopted by the present application is to provide a detection method of a blood analyzer, applied to the above blood analyzer, the detection method comprises:

[0014] The blood analyzer is provided with an automatic sampling mode and an open sampling mode;

[0015] When the mode selection module switches the automatic sampling mode to the open sampling mode, the control module controls the sampling assembly and / or the reaction assembly to be cleaned.

[0016] The step of providing the blood analyzer with an automatic sampling mode and an open sampling mode comprises:

[0017] The control module acquires the sample amount of the blood sample in the automatic sampling mode;

[0018] The step of controlling the sampling assembly and / or the reaction assembly to be cleaned by the control module comprises:

[0019] The control module judges whether the sample amount reaches a preset threshold value;

[0020] If yes, the control module adopts a first cleaning mode to clean the sampling assembly and / or the reaction assembly;

[0021] If not, the control module adopts a second cleaning mode to clean the sampling assembly and / or the reaction assembly, and the cleaning strength of the second cleaning mode is less than that of the first cleaning mode.

[0022] The blood analyzer is provided with an automatic sampling mode and an open sampling mode.

[0023] The blood analyzer is provided with a specific protein single detection mode and a detection mode containing routine blood detection.

[0024] The detection method further comprises:

[0025] When the mode selection module switches the specific protein single detection mode to the detection mode containing routine blood detection, the control module adopts the first cleaning mode to clean the WBC reaction pool and / or the RBC reaction pool of the reaction assembly.

[0026] When the mode selection module selects the automatic sampling mode and the specific protein single detection mode, the control module judges that the detection times of specific proteins are an integer multiple of the preset number of times, and adopts the first cleaning mode to clean the WBC reaction pool and / or the RBC reaction pool.

[0027] The blood analyzer of the present application comprises a mode selection module, a control module, a sampling assembly and a reaction assembly. The mode selection module is used to select one sampling mode from multiple sampling modes of the blood analyzer, and the multiple sampling modes include an automatic sampling mode and an open sampling mode. When the mode selection module switches the automatic sampling mode to the open sampling mode, the control module controls the sampling assembly and / or the reaction assembly to be cleaned. The blood analyzer of the present application can clean the sampling assembly and / or the reaction assembly when the mode selection module switches the automatic sampling mode to the open sampling mode, so as to clean the blood analyzer, avoid pollution accumulation of the blood analyzer, improve the detection accuracy of the blood analyzer, and improve the user experience. BRIEF DESCRIPTION OF DRAWINGS

[0028] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor. Among them:

[0029] Figure 1 is a structural schematic diagram of the first embodiment of the blood analyzer of the present application;

[0030] Figure 2is a flowchart of a first embodiment of the detection method of the blood analyzer of the present application;

[0031] Figure 3 is a flowchart of a second embodiment of the detection method of the blood analyzer of the present application;

[0032] Figure 4 is Figure 3 is a flowchart of a first embodiment of step S303 in

[0033] Figure 5 is a flowchart of a third embodiment of the detection method of the blood analyzer of the present application. DETAILED DESCRIPTION

[0034] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. It can be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application. In addition, it should be noted that, for the convenience of description, only the parts related to the present application are shown in the drawings, but not all the structures. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.

[0035] The terms "first", "second", and the like in the present application are used to distinguish different objects, but not to describe a specific order. In addition, the terms "include" and "have" and any variations thereof are intended to cover the non-exclusive inclusion. For example, a process, method, system, product or device including a series of steps or units is not limited to the listed steps or units, but can optionally include steps or units not listed, or can optionally include other steps or units inherent to the process, method, product or device.

[0036] Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the present application. The appearance of the phrase in various places in the specification indicates that the described feature, structure, or characteristic can be included in at least one embodiment of the present application. The skilled person explicitly and implicitly understands that the embodiments described herein can be combined with other embodiments.

[0037] Please refer to Figure 1 as shown, Figure 1is a structural schematic diagram of a first embodiment of a blood analyzer of the present application. The blood analyzer 10 of the present application comprises a mode selection module 11, a sampling assembly 12, a reaction assembly 13 and a control module 14, wherein the blood analyzer 10 is provided with multiple sampling modes, and the multiple sampling modes comprise an automatic sampling mode and an open sampling mode. For example, the blood analyzer 10 can set the automatic sampling mode and the open sampling mode through the mode selection module 11.

[0038] Wherein, the sampling mode refers to the way in which the blood analyzer 10 draws the blood sample in the test tube through the sampling assembly 12, and the multiple sampling modes comprise the automatic sampling mode and the open sampling mode. When the blood analyzer 10 is in the automatic sampling mode, the sampler of the blood analyzer 10 pushes the test tube to suck the blood sample in the test tube into the blood analyzer 10. For example, the user sets the test tube rack on the blood analyzer 10, and the blood analyzer 10 can continuously detect the blood samples of multiple test tubes on the test tube rack, i.e. the blood analyzer 10 can continuously detect multiple blood samples when in the automatic sampling mode. When the blood analyzer 10 is in the open sampling mode, the user places the test tube under the sampling assembly 12 of the blood analyzer 10, and the blood analyzer 10 draws and detects the blood sample of the test tube.

[0039] The sampling assembly 12 is used to collect blood samples and distribute the collected blood samples to the reaction assembly 13. The blood analyzer 10 can further be provided with detection modes through the mode selection module 11, for example, the blood analyzer 10 is provided with specific protein single detection mode and blood routine detection mode. Therefore, the sampling assembly 12 distributes the collected blood samples to the reaction assembly 13 corresponding to the detection mode.

[0040] Wherein, the blood routine detection includes WBC (White Blood Cell) detection, HGB (Hemoglobin) detection, RBC (red blood cell) detection, DIFF (DIFFerential) detection or RET (reticulocyte) detection. The specific protein includes one of SAA (serum amyloid A protein), CRP (C-reactive protein), TRF (transferrin), Hs-CRP (high-sensitivity C-reactive protein), PCT (procalcitonin) and D-Dimer (D-dimer).

[0041] The specific protein alone detection mode refers to a mode in which only specific protein parameters and HCT detection results are output. The specific protein alone detection mode can be an SAA alone detection mode, a CRP alone detection mode, an SAA+CRP alone detection mode, a TRF alone detection mode, an Hs-CRP alone detection mode, a PCT alone detection mode, or a D-Dimer alone detection mode, etc. The detection mode with blood routine detection refers to a mode in which the output results include the measurement of the total number of white blood cells, red blood cells, platelets, hemoglobin, etc. The detection mode with blood routine detection can be a CBC(complete blood count)+DIFF+CRP detection mode, a CBC+DIFF+SAA detection mode, a CBC+DIFF+SAA+CRP detection mode, a CBC+SAA detection mode, a CBC+CRP detection mode, or a CBC+CRP+SAA detection mode, etc. For example, when the mode selection module 11 selects the detection mode with blood routine detection, the blood analyzer 10 functions as a blood routine, SAA, and CRP combined detection all-in-one machine.

[0042] The reaction assembly 13 is used for detecting the blood sample, that is, the reaction assembly 13 detects the blood sample according to the detection mode. When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the sampling assembly 12 and / or the reaction assembly 13 to be cleaned; specifically, the control module 14 controls the sampling assembly 12 to be cleaned; or the control module 14 controls the reaction assembly 13 to be cleaned; or the control module 14 controls the sampling assembly 12 and the reaction assembly 13 to be cleaned.

[0043] The blood analyzer 10 continuously detects multiple blood samples in the automatic sampling mode, which causes the sampling assembly 12 and / or the reaction assembly 13 to be contaminated and accumulated, affecting the accuracy of subsequent detection of the blood analyzer 10. In this embodiment, when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the sampling assembly 12 and / or the reaction assembly 13 to be cleaned, thereby realizing automatic cleaning of the blood analyzer 10. The blood analyzer 10 can be cleaned to avoid contamination accumulation of the blood analyzer 10, improve the detection accuracy of the blood analyzer 10, and improve the user experience.

[0044] Since the sample amount of the blood sample is different each time in the automatic sampling mode of the blood analyzer 10, the control module 14 further acquires the sample amount of the blood sample in the automatic sampling mode, that is, the sample amount of the blood sample in the automatic sampling mode of the blood analyzer 10.

[0045] When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 determines whether the sample amount reaches a preset threshold; if yes, that is, the sample amount reaches the preset threshold, the control module 14 adopts the first cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13; if no, that is, the sample amount does not reach the preset threshold, the control module 14 adopts the second cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13, wherein the cleaning strength of the second cleaning mode is less than that of the first cleaning mode.

[0046] When the mode selection module 11 switches the automatic sampling mode to the open sampling mode and the sample amount reaches the preset threshold, the control module 14 adopts the first cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13; when the mode selection module 11 switches the automatic sampling mode to the open sampling mode and the sample amount does not reach the preset threshold, the control module 14 adopts the second cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13; thus, the cleaning of the blood analyzer 10 is realized, the pollution accumulation of the blood analyzer 10 is avoided, the detection accuracy of the blood analyzer 10 is improved, and the user experience is improved. In addition, the control module 14 selects the first cleaning mode or the second cleaning mode according to the sample amount to clean the sampling assembly 12 and / or the reaction assembly 13, so as to make the blood analyzer 10 intelligent and save cost; when the sample amount reaches the preset threshold, the control module 14 adopts the first cleaning mode to strengthen the cleaning of the sampling assembly 12 and / or the reaction assembly 13, so as to reduce the probability of failure of the blood analyzer.

[0047] In an embodiment, the reaction assembly 13 includes a WBC reaction cell 131 and an RBC reaction cell 132; when the control module 14 adopts the first cleaning mode to clean the reaction assembly 13, the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132 is at least burned and backflushed.

[0048] When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the blood analyzer 10 adopts the first cleaning mode to clean the reaction assembly 13, that is, the control module 14 controls to clean the front cell and the rear cell of the WBC reaction cell 131, and at least burns and backflushes the gemstone hole of the WBC reaction cell 131; and / or, the control module 14 controls to clean the front cell and the rear cell of the RBC reaction cell 132, and at least burns and backflushes the gemstone hole of the RBC reaction cell 132. Thus, the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132 can be unblocked, the detection accuracy of the blood analyzer 10 is improved, and the user experience is improved.

[0049] In an embodiment, the sampling assembly 12 comprises a sampling needle 121, and the control module 14 controls the sampling needle 121 to suck the isolation bubble through the sampling assembly 12 when the mode selection module 11 switches the automatic sampling mode to the open sampling mode.

[0050] The control module 14 can clean the contamination of the sampling needle 121 in the automatic sampling mode through the sampling assembly 12, thereby improving the detection accuracy of the blood analyzer 10. The control module 14 controls the sampling needle 121 to suck the isolation bubble through the sampling assembly 12, thereby preparing the blood analyzer 10 for the open sampling mode.

[0051] Optionally, the control module 14 controls the sampling assembly 12 and / or the reaction assembly 13 to be cleaned, and the pipeline of the blood analyzer 10 is cleaned when the mode selection module 11 switches the automatic sampling mode to the open sampling mode. The pipeline of the blood analyzer 10 can include a pipeline corresponding to the sampling assembly 12 or a pipeline corresponding to the reaction assembly 13. Therefore, the blood analyzer 10 further cleans the pipeline, thereby cleaning the liquid remaining in the pipeline and improving the detection accuracy of the blood analyzer 10.

[0052] The present application provides a blood analyzer 10 of a second embodiment, which is described based on the blood analyzer 10 of the first embodiment. The blood analyzer 10 is provided with a specific protein detection module and a routine blood detection module. The specific protein detection module is used for specific protein detection of a blood sample, and the routine blood detection module is used for routine blood detection of the blood sample, which is a whole blood sample. The specific protein detection module comprises a specific protein reaction cell in the reaction assembly 13, and the routine blood detection module comprises a WBC reaction cell 131 and an RBC reaction cell 132 in the reaction assembly 13.

[0053] The mode selection module 11 is used for selecting one detection mode from multiple detection modes of the blood analyzer 10. When the mode selection module 11 selects the specific protein single detection mode, the specific protein detection module corresponding to the specific protein single detection mode in the blood analyzer 10 detects the whole blood sample, i.e., the control module 14 is used for controlling the specific protein detection module to detect. At this time, the WBC reaction cell 131 is used as a dilution cell of the whole blood sample, and no hemolytic agent is added, which causes the WBC reaction cell 131 to be easily blocked, so that the blood analyzer 10 cannot be normally used. In addition, the RBC reaction cell 132 of the routine blood detection module 13 is used for detecting the diluted whole blood sample to calculate the HCT value. In order to ensure the accuracy of the HCT value, the RBC reaction cell 132 also needs to be cleaned.

[0054] When the mode selection module 11 switches the specific protein single detection mode to the blood routine detection mode, the control module 14 adopts the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132.

[0055] For example, when the mode selection module 11 selects the automatic sampling mode, and the mode selection module 11 switches the CRP single detection mode to the blood routine detection mode, the control module 14 adopts the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132 to unblock the WBC reaction cell 131 and / or the RBC reaction cell 132. Therefore, when the mode selection module 11 switches the CRP single detection mode to the blood routine detection mode, the control module 14 needs to adopt the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132 to unblock the WBC reaction cell 131 and / or the RBC reaction cell 132 to prevent the WBC reaction cell 131 and / or the RBC reaction cell 132 from being blocked, ensure the blood analyzer 10 to work normally, and improve the detection accuracy of the blood analyzer. In addition, the first cleaning mode is adopted to clean the WBC reaction cell 131 and / or the RBC reaction cell 132 to strengthen the cleaning, which can reduce the probability of the blood analyzer 10 malfunctioning.

[0056] In an embodiment, when the control module 14 adopts the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132, the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132 is burned and backflushed at least once, for example, the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132 is burned and backflushed multiple times to unblock the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132.

[0057] In an embodiment, when the control module 14 adopts the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132, the WBC reaction cell 131 and / or the RBC reaction cell 132 is cleaned by a hemolytic agent, for example, the WBC reaction cell 131 and / or the RBC reaction cell 132 is cleaned by R1 reagent.

[0058] In other embodiments, the WBC reaction cell 131 and / or the RBC reaction cell 132 can be cleaned by a hemolytic agent, and the gemstone hole of the WBC reaction cell 131 and / or the gemstone hole of the RBC reaction cell 132 is burned and backflushed at least once to unblock the WBC reaction cell 131 and / or the RBC reaction cell 132 to improve the unblocking effect of the WBC reaction cell 131 and / or the RBC reaction cell 132.

[0059] In an embodiment, when the mode selection module 11 selects the specific protein single detection mode, the specific protein detection module corresponding to the specific protein single detection mode in the blood analyzer 10 performs detection, i.e., the control module 14 is configured to control the specific protein detection module to perform detection. For example, when the mode selection module 11 selects the SAA single detection mode, the control module 14 is configured to control the specific protein detection module (e.g., the SAA detection module) corresponding to the SAA single detection mode to perform detection on the whole blood sample; or, when the mode selection module 11 selects the CRP single detection mode, the control module 14 is configured to control the specific protein detection module (e.g., the CRP detection module) corresponding to the CRP single detection mode to perform detection on the whole blood sample.

[0060] When the specific protein detection module performs detection, the control module 14 can count the number of detections of the specific protein detection module in the specific protein single detection mode to obtain the number of detections of the specific protein detection module. The control module 14 is configured to compare the number of detections with a preset number of detections to determine whether the number of detections is an integer multiple of the preset number of detections; and the control module 14 is configured to use the first cleaning mode to clean the reaction cell of the blood routine detection module 13 corresponding to the specific protein single detection mode. The integer multiple is a positive integer greater than 0, e.g., 1, 2, 3, 4, 5, or 6.

[0061] The reaction cell of the blood routine detection module 13 corresponding to the specific protein single detection mode includes a WBC reaction cell 131 and an RBC reaction cell 132. When the control module 14 determines that the number of detections of the specific protein detection module 12 is an integer multiple of the preset number of detections, the control module 14 uses the first cleaning mode to clean the WBC reaction cell 131 and / or the RBC reaction cell 132.

[0062] In an embodiment, the control module 14 uses the first cleaning mode to clean the WBC reaction cell 131 to unblock the WBC reaction cell 131 and prevent the WBC reaction cell 131 from being blocked, thereby improving the detection accuracy of the blood analyzer.

[0063] For example, when the control module 14 determines that the number of detections of the specific protein detection module 12 is an integer multiple of the preset number of detections, the control module 14 uses the first cleaning mode to clean the WBC reaction cell 131 to unblock the WBC reaction cell 131. The blood analyzer 10 uses the WBC reaction cell 131 as a dilution cell of the whole blood sample in the CRP single detection mode, which causes the WBC reaction cell 131 to be easily blocked. Therefore, when the control module 14 determines that the number of detections of the specific protein detection module 12 is an integer multiple of the preset number of detections, the control module 14 needs to use the first cleaning mode to clean the WBC reaction cell 131 to unblock the WBC reaction cell 131.

[0064] In an embodiment, the control module 14 adopts the first cleaning mode to clean the RBC reaction cell 132, to unblock the RBC reaction cell 132, to ensure the accuracy of the HCT value, and to improve the detection accuracy of the blood analyzer.

[0065] In an embodiment, the control module 14 adopts the first cleaning mode to clean the WBC reaction cell 131 and the RBC reaction cell 132, to unblock the WBC reaction cell 131 and the RBC reaction cell 132, to prevent the WBC reaction cell 131 from being blocked, to ensure the accuracy of the HCT value, and to improve the detection accuracy of the blood analyzer, so as to facilitate the use of the user.

[0066] The following detailed description describes the detection steps of the specific protein detection module on the whole blood sample when the mode selection module 11 selects the specific protein single detection mode, which includes:

[0067] The control module 14 controls the sampling assembly 12 of the blood analyzer 10 to suck the whole blood sample, and to distribute the whole blood sample to the specific protein reaction cell of the specific protein detection module. Wherein the control module 14 controls the sampling assembly 12 to move to the test tube, to suck the whole blood sample from the test tube; the control module 14 controls the sampling assembly 12 to move to the specific protein reaction cell, to distribute the whole blood sample to the specific protein reaction cell; and the control module 14 controls the sampling assembly 12 to clean.

[0068] The control module 14 adds reagents to the specific protein reaction cell and performs detection to obtain a detection result, which includes a specific protein parameter. Wherein the control module 14 can control the sampling assembly 12 to suck the reagents and inject the reagents into the specific protein reaction cell; and the control module 14 controls the sampling assembly 12 to clean. The whole blood sample and the reagents in the specific protein reaction cell are mixed and reacted, and the blood analyzer 10 detects the liquid in the specific protein reaction cell to obtain the detection result.

[0069] The control module 14 controls the sampling assembly 12 to distribute the whole blood sample to the WBC reaction cell 131, to dilute the whole blood sample. Wherein the control module 14 can control the sampling assembly 12 to distribute the whole blood sample to the WBC reaction cell 131 when distributing the whole blood sample to the specific protein reaction cell, and the WBC reaction cell 131 is used for the whole blood sample to be diluted once, to obtain the diluted sample of the WBC reaction cell 131.

[0070] The control module 14 controls the sampling assembly 12 to add the part of the diluted sample of the WBC reaction pool 131 to the RBC reaction pool 132 of the blood routine detection module to calculate the HCT (Hematocrit) value. After the sampling assembly 12 adds the part of the diluted sample of the WBC reaction pool 131 to the RBC reaction pool 132, the RBC reaction pool 132 performs secondary dilution on the diluted sample, and the blood analyzer 10 detects the liquid in the RBC reaction pool 132 to obtain the HCT value.

[0071] The control module 14 corrects the detection result based on the HCT value, wherein the control module 14 corrects the detection result by using the HCT value to make the corrected detection result more accurate.

[0072] In order to reduce the consumption of hemolytic agent, when the specific protein single detection mode is used, the WBC reaction pool 131 is used as a dilution pool of the whole blood sample and no hemolytic agent is added, so the WBC reaction pool 131 is easy to be blocked, which causes the blood analyzer 10 to be unable to work. The blood analyzer 10 of the present application uses the first cleaning mode to clean the WBC reaction pool 131 when the control module 14 judges that the detection times are an integer multiple of the preset number, which can unblock the WBC reaction pool 131 to prevent the WBC reaction pool 131 from being blocked, ensure that the blood analyzer 10 can work normally, and improve the detection accuracy of the blood analyzer 10.

[0073] In an embodiment, the preset number is 1, and the control module 14 is used to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 by using the first cleaning mode when the control module 14 judges that the detection times are an integer multiple of the preset number. Since any positive integer of the detection times is an integer multiple of the preset number, the control module 14 is used to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 by using the first cleaning mode after each detection is completed, that is, the control module 14 is used to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 by using the first cleaning mode after each detection of the specific protein detection module is completed.

[0074] In an embodiment, the preset number is greater than 1, and the control module 14 is used to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 by using the second cleaning mode when the control module 14 judges that the detection times are not an integer multiple of the preset number. For example, the preset number is 3, the control module 14 counts that the detection times of the specific protein detection module are 2, and the control module 14 judges that the detection times are not an integer multiple of the preset number, and then the control module 14 is used to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 by using the second cleaning mode.

[0075] When the control module 14 is used to clean the WBC reaction cell 131 and / or the RBC reaction cell 132 in the second cleaning mode, the WBC reaction cell 131 and / or the RBC reaction cell 132 can be cleaned by the dilution solution to avoid mutual contamination of multiple whole blood samples in the WBC reaction cell 131 and / or the RBC reaction cell 132.

[0076] When the mode selection module 11 switches the specific protein individual detection mode to the blood routine detection mode, the detection step of the blood routine detection module on the whole blood sample further comprises:

[0077] The control module 14 controls the sampling assembly 12 of the blood analyzer 10 to suck the whole blood sample and distribute the whole blood sample to the WBC reaction cell 131. Wherein the control module 14 controls the sampling assembly 12 to move to the test tube to suck the whole blood sample from the test tube; the control module 14 controls the sampling assembly 12 to move to the WBC reaction cell 131 to distribute the whole blood sample to the WBC reaction cell 131; the control module 14 controls the sampling assembly 12 to clean. The control module 14 performs WBC detection on the whole blood sample through the WBC reaction cell 131 to realize the detection of the blood routine detection module on the whole blood sample.

[0078] The application further provides a blood analyzer 10 of the third embodiment, which is different from the blood analyzer 10 disclosed in the first embodiment in that: when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 acquires the detection mode of the blood analyzer 10 in the automatic sampling mode and controls the reaction cell corresponding to the detection mode in the reaction assembly 13 to clean.

[0079] In an embodiment, the reaction component 13 corresponding to the detection mode is controlled to be cleaned, and specifically, the control module 14 can control the part of the reaction component 13 corresponding to the detection mode to be cleaned. For example, the blood analyzer 10 in the automatic sampling mode can be in the CBC+DIFF+SAA detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the SAA reaction pool) to be cleaned. The blood analyzer 10 in the automatic sampling mode can be in the CBC+DIFF detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the DIFF reaction pool) to be cleaned. The blood analyzer 10 in the automatic sampling mode can be in the CRP single detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the CRP reaction pool) to be cleaned. Thus, the blood analyzer 10 is cleaned, the part of the reaction component 13 corresponding to the detection mode is prevented from being contaminated, the amount of cleaning solution is reduced, and the cost is saved.

[0080] In an embodiment, the reaction component 13 corresponding to the detection mode is controlled to be cleaned, and specifically, the control module 14 can control the part of the reaction component 13 corresponding to the detection mode to be cleaned. For example, the blood analyzer 10 in the automatic sampling mode can be in the CBC+DIFF+SAA detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the SAA reaction pool) to be cleaned. The blood analyzer 10 in the automatic sampling mode can be in the CBC+DIFF detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the DIFF reaction pool) to be cleaned. The blood analyzer 10 in the automatic sampling mode can be in the CRP single detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the part of the reaction component 13 corresponding to the detection mode (the CRP reaction pool) to be cleaned. Thus, the blood analyzer 10 is cleaned, the part of the reaction component 13 corresponding to the detection mode is prevented from being contaminated, the amount of cleaning solution is reduced, and the cost is saved.

[0081] In summary, the blood analyzer 10 of the embodiment only cleans the reaction pool corresponding to the detection mode, can clean the blood analyzer 10, avoids the pollution accumulation of the blood analyzer 10, and improves the detection accuracy of the blood analyzer 10.

[0082] In an embodiment, the reaction assembly 13 includes a plurality of reaction pools (for example, WBC reaction pool 131, RBC reaction pool 132, CRP reaction pool, SAA reaction pool, and DIFF reaction pool). When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the cleaning of the reaction pool corresponding to the detection mode, and the remaining reaction pools are not cleaned.

[0083] For example, when the blood analyzer 10 is in the CBC+DIFF detection mode in the automatic sampling mode, the control module 14 controls the cleaning of the DIFF reaction pool, the WBC reaction pool 131, and the RBC reaction pool 132 in the reaction assembly 13, and does not clean the SAA reaction pool and the CRP reaction pool when the mode selection module 11 switches the automatic sampling mode to the open sampling mode. When the blood analyzer 10 is in the CRP single detection mode in the automatic sampling mode, the control module 14 controls the cleaning of the CRP reaction pool, the WBC reaction pool 131, and the RBC reaction pool 132 in the reaction assembly 13, and does not clean the SAA reaction pool and the DIFF reaction pool when the mode selection module 11 switches the automatic sampling mode to the open sampling mode.

[0084] In an embodiment, when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 uses a first cleaning mode to clean part of the plurality of reaction pools, for example, the control module 14 uses the first cleaning mode to clean the WBC reaction pool 131 and the RBC reaction pool 132 of the reaction assembly 13. When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 uses a second cleaning mode to clean the remaining reaction pools in the plurality of reaction pools, for example, the control module 14 uses the second cleaning mode to clean the specific protein reaction pool (such as the CRP reaction pool, the SAA reaction pool).

[0085] In the embodiment, the control module 14 acquires that the detection mode of the blood analyzer 10 in the automatic sampling mode is a specific protein single detection mode, and the control module 14 uses the first cleaning mode to clean the WBC reaction pool 131 of the reaction assembly 13 when the mode selection module 11 switches the automatic sampling mode to the open sampling mode.

[0086] The control module 14 of the embodiment uses the first cleaning mode to clean part of the plurality of reaction pools, so as to strengthen the cleaning of part of the reaction pools, and can reduce the probability of failure of the blood analyzer 10.

[0087] Referring to Figure 2 as shown, Figure 2 is a flowchart of a first embodiment of a detection method of a blood analyzer of the present application. The detection method of the present embodiment is applied to the blood analyzer 10 described above, and the detection method comprises the following steps:

[0088] S201: The blood analyzer 10 is provided with an automatic sampling mode and an open sampling mode.

[0089] The blood analyzer 10 can set the automatic sampling mode and the open sampling mode through the mode selection module 11.

[0090] S202: When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the sampling assembly 12 and / or the reaction assembly 13 to perform cleaning.

[0091] The control module 14 controls the sampling assembly 12 and / or the reaction assembly 13 to perform cleaning; specifically, the control module 14 controls the sampling assembly 12 to perform cleaning; or the control module 14 controls the reaction assembly 13 to perform cleaning; or the control module 14 controls the sampling assembly 12 and the reaction assembly 13 to perform cleaning. Thus, the blood analyzer 10 is automatically cleaned, the blood analyzer 10 can be cleaned, the accumulation of pollution of the blood analyzer 10 is avoided, the detection accuracy of the blood analyzer 10 is improved, and the user's use experience is improved.

[0092] Step S201 comprises: the control module 14 further acquires the sample amount of the blood sample in the automatic sampling mode, i.e. the sample amount of the blood sample in the automatic sampling mode of the blood analyzer 10.

[0093] Step S202 comprises: when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 judges whether the sample amount reaches a preset threshold; if yes, i.e. the sample amount reaches the preset threshold, the control module 14 uses a first cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13; if no, i.e. the sample amount does not reach the preset threshold, the control module 14 uses a second cleaning mode to clean the sampling assembly 12 and / or the reaction assembly 13, wherein the cleaning strength of the second cleaning mode is less than that of the first cleaning mode.

[0094] The control module 14 of the present embodiment selects the first cleaning mode or the second cleaning mode according to the sample amount to clean the sampling assembly 12 and / or the reaction assembly 13, so as to make the blood analyzer 10 intelligent and save costs; when the sample amount reaches the preset threshold, the control module 14 uses the first cleaning mode to perform intensive cleaning of the sampling assembly 12 and / or the reaction assembly 13, which can reduce the probability of failure of the blood analyzer.

[0095] Referring to Figure 3 as shown, Figure 3 is a flowchart of a second embodiment of the detection method of the blood analyzer of the present application. The detection method of the present embodiment comprises the following steps:

[0096] S301: The blood analyzer 10 is provided with multiple detection modes, and the multiple detection modes include a specific protein single detection mode and a detection mode containing routine blood detection.

[0097] The multiple detection modes of the blood analyzer 10 include the specific protein single detection mode and the detection mode containing routine blood detection, and the specific protein single detection mode can be a SAA single detection mode or a CRP single detection mode.

[0098] S302: When the mode selection module 11 switches the specific protein single detection mode to the detection mode containing routine blood detection, the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0099] For example, the mode selection module 11 switches the CRP single detection mode to the routine blood detection mode, and the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 to unblock the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0100] The present embodiment adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 when the mode selection module 11 switches the specific protein single detection mode to the detection mode containing routine blood detection. For example, the mode selection module 11 switches the CRP single detection mode to the routine blood detection mode, and the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 to unblock the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0101] S303: When the mode selection module 11 selects the automatic sampling mode and the specific protein single detection mode, the control module 14 controls the specific protein detection module to perform detection.

[0102] When the mode selection module 11 selects the automatic sampling mode and the specific protein single detection mode, the specific protein detection module corresponding to the specific protein single detection mode in the blood analyzer 10 performs detection, i.e., the control module 14 is used to control the specific protein detection module to perform detection.

[0103] S304: When the control module 14 judges that the detection times is an integer multiple of the preset times, the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0104] When the specific protein detection module performs detection, the control module 14 can count the detection times of the specific protein detection module in the specific protein single detection mode to obtain the detection times of the specific protein detection module. The control module 14 is configured to compare the detection times of the specific protein detection module with the preset times, and judge whether the detection times is an integer multiple of the preset times. If yes, the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132; if no, the step S305 is entered.

[0105] S305: When the control module 14 judges that the detection times is not an integer multiple of the preset times, the control module 14 adopts the second cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0106] When the control module 14 is configured to adopt the second cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132, the WBC reaction pool 131 and / or the RBC reaction pool 132 can be cleaned by the dilution liquid to avoid mutual pollution of multiple whole blood samples in the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0107] The blood analyzer 10 of the embodiment is configured to adopt the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 when the specific protein single detection mode is adopted and the detection times of the specific protein detection module 12 is an integer multiple of the preset times, which can clean the WBC reaction pool 131 and / or the RBC reaction pool 132 to prevent the WBC reaction pool 131 and / or the RBC reaction pool 132 from being blocked, and improve the detection accuracy of the blood analyzer 10.

[0108] In step S304, the preset times is 1, and the control module 14 is configured to adopt the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 when the detection times is an integer multiple of the preset times. Since the detection times is an integer multiple of the preset times, the control module 14 is configured to adopt the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 after each detection, i.e., the control module 14 adopts the first cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132 after each detection of the specific protein detection module 12.

[0109] In step S305, the preset number of times is greater than 1, and when the control module 14 judges that the detection number of times is not an integer multiple of the preset number of times, the control module 14 is configured to adopt the second cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132. For example, the preset number of times is 3, and the control module 14 counts that the detection number of times of the specific protein detection module 12 is 2, and then the control module 14 judges that the detection number of times is not an integer multiple of the preset number of times, and then adopts the second cleaning mode to clean the WBC reaction pool 131 and / or the RBC reaction pool 132.

[0110] Please refer to Figure 4 shown in FIG. 3, Figure 4 is Figure 3 the flowchart of the first embodiment of step S303 in FIG. 3. Step S303 includes the following steps:

[0111] S401: The control module 14 controls the sampling assembly 12 of the blood analyzer 10 to suck the whole blood sample, and distributes the whole blood sample to the specific protein reaction pool of the specific protein detection module.

[0112] The control module 14 controls the sampling assembly 12 to move to the test tube to suck the whole blood sample from the test tube; the control module 14 controls the sampling assembly 12 to move to the specific protein reaction pool to distribute the whole blood sample to the specific protein reaction pool; and the control module 14 controls the sampling assembly 12 to clean.

[0113] S402: The control module 14 adds reagents to the specific protein reaction pool and performs detection to obtain a detection result.

[0114] The control module 14 can control the sampling assembly 12 to suck the reagents and inject the reagents into the specific protein reaction pool; and the control module 14 controls the sampling assembly 12 to clean. The whole blood sample and the reagents in the specific protein reaction pool are mixed and reacted, and the blood analyzer 10 detects the liquid in the specific protein reaction pool to obtain a detection result.

[0115] S403: The control module 14 controls the sampling assembly 12 to distribute the whole blood sample to the WBC reaction pool 131 to dilute the whole blood sample.

[0116] The control module 14 can control the sampling assembly 12 to distribute the whole blood sample to the WBC reaction pool 131 when distributing the whole blood sample to the specific protein reaction pool, and the WBC reaction pool 131 is used for diluting the whole blood sample once to obtain the diluted sample of the WBC reaction pool 131.

[0117] S404: The control module 14 controls the sampling assembly 12 to add the diluted sample of the WBC reaction pool 131 to the RBC reaction pool 132 of the blood routine detection module to calculate the HCT value.

[0118] After the sampling assembly 12 adds the diluted sample of the WBC reaction cell 131 to the RBC reaction cell 132, the RBC reaction cell 132 performs secondary dilution on the diluted sample, and the blood analyzer 10 detects the liquid in the RBC reaction cell 132 to obtain the HCT value.

[0119] S405: The control module 14 corrects the detection result based on the HCT value.

[0120] In this embodiment, the control module 14 corrects the detection result by using the HCT value, so that the corrected detection result is more accurate.

[0121] Please refer to Figure 5 , Figure 5 is a flowchart of a third embodiment of the detection method of the blood analyzer of the present application. The detection method of the present embodiment comprises the following steps:

[0122] S501: The blood analyzer 10 is provided with an automatic sampling mode and an open sampling mode.

[0123] Step S501 is the same as step S201, which will not be repeated here.

[0124] S502: When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 obtains the detection mode of the blood analyzer 10 in the automatic sampling mode and controls the reaction cell corresponding to the detection mode in the reaction assembly 13 to be cleaned.

[0125] In this embodiment, the detection mode of the blood analyzer 10 in the automatic sampling mode is the CBC+DIFF+SAA detection mode, and when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the SAA reaction cell in the reaction assembly 13 to be cleaned. Therefore, the blood analyzer 10 of the present embodiment only cleans the reaction cell corresponding to the detection mode, which can clean the blood analyzer 10 and avoid the accumulation of pollution of the blood analyzer 10, thereby improving the detection accuracy of the blood analyzer 10.

[0126] In an embodiment, the reaction assembly 13 comprises a plurality of reaction cells. When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the reaction cell corresponding to the detection mode to be cleaned, and the remaining reaction cells are not cleaned.

[0127] For example, the blood analyzer 10 is in the CBC+DIFF detection mode in the automatic sampling mode, when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 controls the cleaning of the DIFF reaction cell, the WBC reaction cell 131 and the RBC reaction cell 132 in the reaction assembly 13, and does not clean the SAA reaction cell and the CRP reaction cell. Therefore, the amount of cleaning liquid (e.g. diluent) can be reduced, and the cost can be reduced.

[0128] In an embodiment, when the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 uses a first cleaning mode to clean part of the reaction cells, for example, the control module 14 uses the first cleaning mode to clean the WBC reaction cell 131 and the RBC reaction cell 132 in the reaction assembly 13, so that the part of the reaction cells can be cleaned intensively, and the probability of failure of the blood analyzer 10 can be reduced. When the mode selection module 11 switches the automatic sampling mode to the open sampling mode, the control module 14 uses a second cleaning mode to clean the remaining reaction cells, for example, the control module 14 uses the second cleaning mode to clean the specific protein reaction cells (e.g. the CRP reaction cell and the SAA reaction cell).

[0129] In several embodiments provided in the present application, it should be understood that the disclosed devices can be implemented in other manners. For example, the above-described device embodiments are merely illustrative, and the division of the modules or units can be different, for example, some or all of the modules or units can be combined or integrated into another system, or some features can be ignored or not executed.

[0130] The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, i.e. they can be located in one place or distributed on multiple network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the present embodiment.

[0131] In addition, each functional unit in each embodiment of the present application can be integrated into a processing unit, or each unit can exist physically, or two or more units can be integrated into one unit. The integrated unit can be realized in the form of hardware or in the form of a software functional unit.

[0132] The above merely describes the embodiments of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation according to the content of the present application specification and drawings, or direct or indirect application in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A blood analyzer, characterized in that, The blood analyzer includes a mode selection module, a control module, a sampling component, and a reaction component. The sampling component is used to distribute the collected blood sample to the reaction component, and the reaction component is used to detect the blood sample. The mode selection module is used to select one injection mode from multiple injection modes of the blood analyzer, including an automatic injection mode and an open injection mode. When the mode selection module switches the automatic sampling mode to the open sampling mode, the control module controls the sampling component and / or the reaction component to be cleaned. The blood analyzer is equipped with a specific protein detection mode and a blood routine test mode; The control module is used to perform the following steps: When the mode selection module selects the specific protein detection mode, the control module is used to control the specific protein detection module to perform the detection. The WBC reaction chamber is used as a dilution chamber for the whole blood sample, and the RBC reaction chamber of the blood routine detection module is used to detect the diluted whole blood sample. When the mode selection module switches the specific protein detection mode to the blood routine test mode, the control module uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber of the reaction component. When the mode selection module selects the automatic sample introduction mode and the specific protein individual detection mode, the control module determines that the number of detections of the specific protein is an integer multiple of the preset number, and uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber.

2. The blood analyzer according to claim 1, characterized in that, The control module acquires the sample volume of the blood sample in the automatic sampling mode; when the mode selection module switches the automatic sampling mode to the open sampling mode and the sample volume reaches a preset threshold, the control module uses a first cleaning mode to clean the sampling component and / or the reaction component.

3. The blood analyzer according to claim 2, characterized in that, When the mode selection module switches the automatic sampling mode to the open sampling mode and the sample volume does not reach the preset threshold, the control module uses a second cleaning mode to clean the sampling component and / or the reaction component. The cleaning intensity of the second cleaning mode is less than that of the first cleaning mode.

4. The blood analyzer according to claim 2, characterized in that, The reaction assembly includes a WBC reaction tank and an RBC reaction tank. When the control module cleans the reaction assembly using the first cleaning mode, the sapphire holes of the WBC reaction tank and / or the sapphire holes of the RBC reaction tank are subjected to at least one burning and backflushing.

5. The blood analyzer according to claim 4, characterized in that, The sampling component includes a sampling needle. The control module cleans the sampling needle through the sampling component and controls the sampling needle to draw in isolation air bubbles.

6. The blood analyzer according to claim 4, characterized in that, The blood analyzer is equipped with a specific protein detection mode and a blood routine test mode. When the mode selection module switches the specific protein detection mode to the blood routine test mode, the control module uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber.

7. The blood analyzer according to claim 6, characterized in that, When the mode selection module selects the automatic sample introduction mode and the specific protein individual detection mode, the control module determines that the number of detections of the specific protein is an integer multiple of the preset number, and uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber.

8. A detection method for a blood analyzer, characterized in that, The detection method, applied to a blood analyzer as described in any one of claims 1-7, comprises: The blood analyzer is equipped with an automatic sampling mode and an open sampling mode; When the mode selection module switches the automatic injection mode to the open injection mode, the control module controls the sampling component and / or the reaction component to be cleaned.

9. The detection method according to claim 8, characterized in that, The steps for setting up the blood analyzer in automatic sampling mode and open sampling mode include: The control module acquires the sample volume of the blood sample in the automatic sampling mode; The step of the control module controlling the sampling component and / or the reaction component to perform cleaning includes: The control module determines whether the sample size has reached a preset threshold. If so, the control module uses a first cleaning mode to clean the sampling component and / or the reaction component; If not, the control module uses a second cleaning mode to clean the sampling component and / or the reaction component, wherein the cleaning intensity of the second cleaning mode is less than that of the first cleaning mode.

10. The detection method according to claim 9, characterized in that, The steps for setting up the blood analyzer in automatic sampling mode and open sampling mode include: The blood analyzer has a specific protein detection mode and a routine blood test mode. The detection method further includes: When the mode selection module switches the specific protein detection mode to the blood routine test mode, the control module uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber of the reaction component. When the mode selection module selects the automatic sample introduction mode and the specific protein individual detection mode, the control module determines that the number of detections of the specific protein is an integer multiple of the preset number, and uses the first cleaning mode to clean the WBC reaction chamber and / or RBC reaction chamber.

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