A vacuum adsorption packaging device and a packaging method

Abstract

The present invention discloses a vacuum adsorption and sub-packaging device and a sub-packaging method. Among them, the vacuum adsorption and sub-packaging device includes a mounting base and a rotating mechanism. The mounting base is provided with a first driving device, a first support seat, and a second support seat. The first driving device can move along the width direction of the mounting base. A first container is provided on the top of the first support seat, and a second container is provided on the second support seat. Openings are provided at the tops of the first container and the second container. The first support seat is provided with a second driving device for driving the first container to move in the height direction. The rotating mechanism includes a rotating shaft, a clamping device for clamping the first container, and a third driving device for controlling the clamping or loosening of the clamping device. The first driving device is used to drive the rotating shaft to rotate axially. One end of the rotating shaft is connected to the first driving device, and an adsorption device is provided at the other end. The adsorption device is arranged corresponding to the opening. This vacuum adsorption and sub-packaging device has stable working performance, high sub-packaging efficiency, and high yield rate.

Description

Technical Field

[0001] The present invention relates to the technical field of dispensing devices, and particularly to a vacuum adsorption dispensing device and a dispensing method. Background Art

[0002] During the production process of products such as medical products, cosmetics, and biological reagents, it is necessary to quickly and accurately dispense freeze-dried microspheres into specified containers to avoid moisture absorption, contamination, and damage of the freeze-dried microspheres. Common packaging forms of freeze-dried microspheres include microfluidic chips, eight-connected tubes, and vials, etc. Different packaging forms directly affect the dispensing efficiency, dispensing structure size, and mechanism complexity of the freeze-dried microspheres. Existing dispensing methods include:

[0003] (1) Manual dispensing, that is, the staff holds tweezers to pick up freeze-dried microspheres one by one. This operation form not only has low efficiency, but also causes irreversible damage to the freeze-dried microspheres, with a low yield. Moreover, manual non-closed operation has high requirements for the humidity of the operation environment, and the freeze-dried microspheres are prone to moisture absorption and contamination;

[0004] (2) Pneumatic-channel type dispensing, that is, a form of dispensing that combines air flow and channels. This dispensing form has extremely high requirements for air pressure, channel diameter tolerance, and smoothness. It is difficult to precisely control the air flow, and the channel processing is difficult. Moreover, the dispensing channels are extremely prone to adhering to freeze-dried microsphere powder, resulting in channel blockage, high equipment failure rate, difficult cleaning, inconvenient maintenance. And since the size of the dispensing channels has been determined, for freeze-dried microspheres of different diameters, the versatility of the dispenser is not high, and freeze-dried microspheres of the same size but different types will be contaminated by the freeze-dried microsphere powder remaining in the channels.

[0005] Therefore, these existing dispensing forms all have disadvantages such as low efficiency and high failure rate. Summary of the Invention

[0006] An object of the present invention is to solve at least one of the technical problems existing in the prior art, and to provide a vacuum adsorption dispensing device and a dispensing method. Among them, the vacuum adsorption dispensing device has a high dispensing yield and high working efficiency.

[0007] The technical solution adopted by the present invention to solve its technical problems is:

[0008] A vacuum adsorption and sub-packaging device includes a mounting base and a rotating mechanism. The mounting base is provided with a first driving device, a first support seat, and a second support seat. The first driving device can move along the width direction of the mounting base. The first support seat and the second support seat are arranged along the width direction of the mounting base. The top of the first support seat is provided with a first container for containing freeze-dried balls. The second support seat is provided with a second container for sub-packaging freeze-dried balls. Openings for taking and placing freeze-dried balls are formed at the tops of the first container and the second container. The first support seat is provided with a second driving device for driving the first container to move in the height direction. The rotating mechanism includes a rotating shaft, a clamping device for clamping the first container, and a third driving device for controlling the clamping device to clamp or loosen. The rotating shaft is arranged along the length direction of the mounting base. The first driving device is used to drive the rotating shaft to rotate axially. One end of the rotating shaft is connected to the first driving device, and the other end is provided with an adsorption device for adsorbing freeze-dried balls. The adsorption device is arranged corresponding to the opening.

[0009] Preferably, the adsorption device includes a connecting component, a first pneumatic joint, and a suction cup for adsorbing freeze-dried balls. The connecting component is arranged on the outer periphery of the rotating shaft. The first pneumatic joint and the suction cup are respectively arranged on both sides of the connecting component. The first pneumatic joint is communicated with the suction cup. The suction cup is detachably connected to the connecting component.

[0010] Preferably, the clamping device includes a first clamping arm and a second clamping arm for clamping the outer periphery of the first container. The first clamping arm and the second clamping arm are arranged along the width direction of the mounting base.

[0011] Preferably, the third driving device is installed on the outer periphery of the rotating shaft. The third driving device is detachably connected to the first clamping arm and the second clamping arm.

[0012] Preferably, the third driving device includes a cylinder for controlling the first clamping arm and the second clamping arm. A second pneumatic joint is arranged on the cylinder.

[0013] Preferably, the first driving device includes a driving motor and a driving shaft. The driving shaft is coaxially arranged with the rotating shaft. A coupling is arranged between the driving shaft and the rotating shaft.

[0014] Preferably, a third support seat is arranged on the mounting base. A fourth support seat is arranged on the third support seat. The first driving device is installed on the fourth support seat. A slide rail is arranged along the width direction of the mounting base on the third support seat. A slider cooperating with the slide rail is arranged at the bottom of the fourth support seat.

[0015] Preferably, a limit block for limiting the stroke of the first driving device is provided on the third support base, and the limit blocks are located on both sides of the slide rail along the width direction of the mounting base.

[0016] Preferably, an induction sheet is provided on the outer periphery of the rotating shaft, and an inductor is provided on the fourth support base, and the inductor is arranged corresponding to the induction sheet.

[0017] The present invention also provides a dispensing method using the vacuum adsorption dispensing device, including the following steps:

[0018] Step 1: The first container is filled with freeze-dried pellets to be dispensed. Control the second driving device to drive the first container to rise, insert the adsorption device into the opening of the first container, and control the clamping device to clamp the first container.

[0019] Step 2: The second driving device descends. After the second driving device is separated from the first container, the first driving device drives the first container to rotate, so that the first container rotates from an upright state to an inverted state, and the adsorption device is turned on to adsorb the freeze-dried pellets.

[0020] Step 3: The first driving device drives the first container to rotate to an upright state, the second driving device rises, the clamping device releases the first container, and the second driving device drives the first container to descend.

[0021] Step 4: The first driving device drives the rotating mechanism to move, so that the adsorption device is located above the opening of the second container. The adsorption device is turned off. After the freeze-dried pellets are separated from the adsorption device, they fall into the second container, and the dispensing of the freeze-dried pellets is completed.

[0022] At least one of the technical solutions in the above technical solutions has the following advantages or beneficial effects: When the vacuum adsorption dispensing device is used, first, the second driving device drives the first container to rise, so that the adsorption device extends into the opening of the first container, and the clamping device clamps the first container. After the second driving device drives the first container to descend, the first driving device drives the first container to rotate, so that the first container is turned from an upright state to an inverted state, and then the adsorption device is turned on to adsorb the freeze-dried pellets. Then, the first driving device moves the adsorption device above the second container, turns off the adsorption device, and puts the freeze-dried pellets into the second container to complete the dispensing of the freeze-dried pellets. The vacuum adsorption dispensing device does not have artificial contact with the freeze-dried pellets, effectively avoiding external contamination, and the contact between the freeze-dried pellets and the adsorption device is less, avoiding excessive damage to the freeze-dried pellets, ensuring the integrity of the freeze-dried pellets, and at the same time reducing the failure rate of the equipment. The vacuum adsorption dispensing device is suitable for freeze-dried pellets in multi-well packaging such as microfluidic chips and octuplets, with stable working performance, high dispensing efficiency, and high yield.

[0023] Additional aspects and advantages of the present invention will be given in part in the following description, become apparent in part from the following description, or be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The above and / or additional aspects and advantages of the present invention will become apparent and be readily understood from the following description of embodiments in conjunction with the accompanying drawings, in which:

[0025] Figure 1 is a schematic structural diagram of an embodiment of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0026] This part will describe in detail the specific embodiments of the present invention. The preferred embodiments of the present invention are shown in the accompanying drawings. The function of the drawings is to supplement the description in the text part of the specification, enabling people to intuitively and vividly understand each technical feature and the overall technical solution of the present invention. However, it should not be construed as a limitation on the protection scope of the present invention.

[0027] In the present invention, when directions (up, down, left, right, front, and back) are described, it is only for the convenience of describing the technical solution of the present invention, rather than indicating or implying that the technical features referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation on the present invention.

[0028] In the present invention, the meaning of "several" is one or more, the meaning of "multiple" is two or more, and "greater than", "less than", "exceeding", etc. are understood to exclude the recited number; "above", "below", "within", etc. are understood to include the recited number. In the description of the present invention, if "first" and "second" are described, they are only for the purpose of distinguishing technical features and should not be construed as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features or implicitly indicating the sequence relationship of the indicated technical features.

[0029] In the present invention, unless otherwise clearly defined, terms such as "arranged", "installed", "connected", etc. should be understood in a broad sense. For example, they can be directly connected, or indirectly connected through an intermediate medium; they can be fixedly connected, or detachably connected, or integrally formed; they can be mechanically connected, or electrically connected or capable of communicating with each other; they can be the communication inside two components or the interaction relationship between two components. Those skilled in the art can reasonably determine the specific meanings of the above terms in the present invention in combination with the specific content of the technical solution.

[0030] An embodiment of the present invention provides a vacuum adsorption and sub-packaging device. Refer to Figure 1, including an installation base 100 and a rotating mechanism 300. A first driving device 200, a first support base 120, and a second support base 130 are provided on the installation base 100. The first driving device 200 can move along the width direction of the installation base 100. The first support base 120 and the second support base 130 are arranged along the width direction of the installation base 100. A first container 121 for containing freeze-dried microspheres is provided at the top of the first support base 120. A second container 131 for sub-packaging freeze-dried microspheres is provided on the second support base 130. Openings for taking and placing freeze-dried microspheres are provided at the tops of the first container 121 and the second container 131. A second driving device 122 for driving the first container 121 to move in the height direction is provided on the first support base 120. The rotating mechanism 300 includes a rotating shaft 310, a clamping device 320 for clamping the first container 121, and a third driving device 330 for controlling the clamping device 320 to clamp or loosen. The rotating shaft 310 is arranged along the length direction of the installation base 100. The first driving device 200 is used to drive the rotating shaft 310 to rotate axially. One end of the rotating shaft 310 is connected to the first driving device 200, and an adsorption device 340 for adsorbing freeze-dried microspheres is provided at the other end. The adsorption device 340 is arranged corresponding to the opening. During use, first, the second driving device 122 drives the first container 121 to rise, so that the adsorption device 340 extends into the opening of the first container 121. The clamping device 320 clamps the first container 121. The first driving device 200 drives the first container 121 to rotate. After the second driving device 122 drives the first container 121 to descend, the first container 121 is turned from an upright state to an inverted state. Then, the adsorption device 340 is turned on to adsorb the freeze-dried microspheres. Then, the adsorption device 340 is moved above the second container 131 through the first driving device 200. The adsorption device 340 is turned off, and the freeze-dried microspheres are put into the second container 131 to complete the sub-packaging of the freeze-dried microspheres. This vacuum adsorption sub-packaging device has no manual contact with the freeze-dried microspheres, effectively avoids external contamination, and the contact between the freeze-dried microspheres and the adsorption device 340 is less, avoiding excessive damage to the freeze-dried microspheres and ensuring the integrity of the freeze-dried microspheres. At the same time, it also reduces the failure rate of the equipment. This vacuum adsorption sub-packaging device is applicable to freeze-dried microspheres for multi-well packaging such as microfluidic chips and eight-connected tubes, with stable working performance, high sub-packaging efficiency, and high qualified product rate, and can be widely used in industries such as medical and biochemical

[0031] In some embodiments, see Figure 1, the adsorption device 340 includes a connecting component 341, a first pneumatic joint 342, and a suction cup 343 for adsorbing freeze-dried pellets. The connecting component 341 is provided on the outer periphery of the rotating shaft 310. The first pneumatic joint 342 and the suction cup 343 are respectively provided on both sides of the connecting component 341. The first pneumatic joint 342 is connected to the suction cup 343. The suction cup 343 is detachably connected to the connecting component 341. The first pneumatic joint 342 is connected to a vacuum, so that a vacuum environment is formed inside the suction cup 343, which is convenient for adsorbing freeze-dried pellets and has high dispensing efficiency. If it is necessary to dispense freeze-dried pellets of different sizes or types, different suction cups 343 can be used. The detachable connection method makes the suction cup 343 easy to clean and replace. Preferably, the suction cup 343 can also adopt an integrated suction nozzle to realize one-to-one simultaneous dispensing of freeze-dried pellets at the hole positions, abandoning the previous single-hole-by-single dispensing, improving the production efficiency and reducing the labor force.

[0032] As a preferred embodiment of the present invention, refer to Figure 1 , the clamping device 320 includes a first clamping arm 321 and a second clamping arm 322 for clamping the outer periphery of the first container 121. The first clamping arm 321 and the second clamping arm 322 are arranged along the width direction of the mounting base 100.

[0033] Preferably, refer to Figure 1 , the third driving device 330 is installed on the outer periphery of the rotating shaft 310. The third driving device 330 is detachably connected to the first clamping arm 321 and the second clamping arm 322. If it is necessary to dispense freeze-dried pellets of different sizes or types, different clamping devices 320 can be used. The detachable connection method makes the first clamping arm 321 and the second clamping arm 322 easy to clean and replace.

[0034] In some embodiments, refer to Figure 1 , the third driving device 330 includes a cylinder for controlling the first clamping arm 321 and the second clamping arm 322. A second pneumatic joint 331 is provided on the cylinder, which is convenient for controlling the first clamping arm 321 and the second clamping arm 322 through the pneumatic joint 331.

[0035] Preferably, refer to Figure 1 , the first driving device 200 includes a driving motor 210 and a driving shaft 220. The driving shaft 220 is coaxially arranged with the rotating shaft 310. A coupling 230 is provided between the driving shaft 220 and the rotating shaft 310, which plays a role of buffering and shock absorption.

[0036] Preferably, refer to Figure 1, a third support base 110 is provided on the mounting base 100, a fourth support base 240 is provided on the third support base 110, the first driving device 200 is mounted on the fourth support base 240, a slide rail 111 is provided on the third support base 110 along the width direction of the mounting base 100, and a slider cooperating with the slide rail 111 is provided at the bottom of the fourth support base 240, facilitating the first driving device 200 to drive the rotating mechanism 300 to operate.

[0037] In some embodiments, refer to Figure 1 , a limit block 112 for restricting the stroke of the first driving device 200 is provided on the third support base 110, and the limit block is located on both sides of the slide rail 111 along the width direction of the mounting base 100, preventing the first driving device 200 from derailing during operation.

[0038] As a preferred embodiment of the present invention, refer to Figure 1 , an induction sheet 311 is provided on the outer periphery of the rotating shaft 310, an inductor 241 is provided on the fourth support base 240, and the inductor 241 is arranged corresponding to the induction sheet 311.

[0039] Preferably, refer to Figure 1 , both the first container 121 and the second container 131 include vials for containing and sub-packaging freeze-dried beads.

[0040] When in use, the vacuum adsorption sub-packaging device can be placed in a closed working space, avoiding the moisture absorption of the freeze-dried beads, maintaining a sterile and closed environment in the working space, and preventing the freeze-dried beads from being contaminated.

[0041] The present invention also provides a sub-packaging method using the vacuum adsorption sub-packaging device, including the following steps:

[0042] Step 1: The first container 121 contains the freeze-dried beads to be sub-packaged. Control the second driving device 122 to drive the first container 121 to rise, so that the adsorption device 340 is inserted into the opening of the first container 121, and then the clamping device 320 clamps the first container 121.

[0043] Step 2: Control the second driving device 122 to descend, so that the second driving device 122 is separated from the first container 121. The first driving device 200 drives the first container 121 to rotate, so that the first container 121 rotates from an upright state to an inverted state. In the inverted state, the opening of the first container 121 faces downward. Preferably, the rotation angle is 180 degrees, and the adsorption device 340 is turned on to adsorb the freeze-dried beads.

[0044] Step 3: The first driving device 200 drives the first container 121 to rotate to the upright state, the second driving device 122 rises, the clamping device 320 releases the first container 121, and the second driving device 122 drives the first container 121 to descend.

[0045] Step Four: The first driving device 200 drives the rotating mechanism 300 to move, so that the adsorption device 340 is located above the opening of the second container 131. Close the adsorption device 340, separate the freeze-dried pellets from the adsorption device 340, and the freeze-dried pellets fall into the second container 131 to complete the packaging of the freeze-dried pellets.

[0046] Step Five: The first driving device 200 moves to the initial state, that is, above the opening of the first container 121, to prepare for the next cycle.

[0047] In the description of this specification, the description with reference to terms such as "example", "embodiment" or "some embodiments" means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in a suitable manner in any one or more embodiments or examples.

[0048] Certainly, the present invention is not limited to the above embodiments. Those skilled in the art can make equivalent deformations or substitutions without departing from the spirit of the present invention, and these equivalent deformations or substitutions are all included in the scope defined by the claims of this application.

Claims

1. A vacuum adsorption and sub-packaging device, characterized in that: It includes an installation base and a rotating mechanism. A first driving device, a first support base and a second support base are provided on the installation base. The first driving device can move along the width direction of the installation base. The first support base and the second support base are arranged along the width direction of the installation base. A first container for containing freeze-dried balls is provided on the top of the first support base. A second container for sub-packaging freeze-dried balls is provided on the second support base. Openings for taking and placing freeze-dried balls are provided at the tops of the first container and the second container. A second driving device for driving the first container to move in the height direction is provided on the first support base. The rotating mechanism includes a rotating shaft, a clamping device for clamping the first container, and a third driving device for controlling the clamping device to clamp or loosen. The rotating shaft is arranged along the length direction of the installation base. The first driving device is used to drive the rotating shaft to rotate axially. One end of the rotating shaft is connected to the first driving device, and an adsorption device for adsorbing freeze-dried balls is provided at the other end. The adsorption device is arranged corresponding to the opening.

2. The vacuum adsorption and sub-packaging device according to claim 1, characterized in that: The adsorption device includes a connecting component, a first pneumatic joint and a suction cup for adsorbing freeze-dried balls. The connecting component is arranged on the outer periphery of the rotating shaft. The first pneumatic joint and the suction cup are respectively arranged on both sides of the connecting component. The first pneumatic joint is communicated with the suction cup. The suction cup is detachably connected to the connecting component.

3. The vacuum adsorption and dispensing device according to claim 1, characterized in that: The clamping device includes a first clamping arm and a second clamping arm for clamping the outer periphery of the first container. The first clamping arm and the second clamping arm are arranged along the width direction of the installation base.

4. The vacuum adsorption and sub-packaging device according to claim 3, characterized in that: The third driving device is installed on the outer periphery of the rotating shaft. The third driving device is detachably connected to the first clamping arm and the second clamping arm.

5. The vacuum adsorption and sub-packaging device according to claim 4, wherein: The third driving device includes a cylinder for controlling the first clamping arm and the second clamping arm. A second pneumatic joint is provided on the cylinder.

6. The vacuum adsorption and dispensing device according to claim 1, wherein: The first driving device includes a driving motor and a driving shaft. The driving shaft is coaxially arranged with the rotating shaft. A coupling is provided between the driving shaft and the rotating shaft.

7. The vacuum adsorption and sub-packaging device according to claim 1, wherein: A third support base is provided on the installation base. A fourth support base is provided on the third support base. The first driving device is installed on the fourth support base. A slide rail is arranged along the width direction of the installation base on the third support base. A slider cooperating with the slide rail is provided at the bottom of the fourth support base.

8. The vacuum adsorption and sub-packaging device according to claim 7, wherein: Limit blocks for limiting the stroke of the first driving device are provided on the third support base. The limit blocks are located on both sides of the slide rail along the width direction of the installation base.

9. The vacuum adsorption and sub-packaging device according to claim 8, wherein: An induction sheet is provided on the outer periphery of the rotating shaft. An inductor is provided on the fourth support base. The inductor is arranged corresponding to the induction sheet.

10. A dispensing method using the vacuum adsorption dispensing device described in claim 1, characterized in that It includes the following steps: Step 1: The first container is filled with freeze-dried balls to be sub-packaged. Control the second driving device to drive the first container to rise. The adsorption device is inserted into the opening of the first container. Control the clamping device to clamp the first container. Step 2: The second driving device descends. After the second driving device is separated from the first container, the first driving device drives the first container to rotate, so that the first container rotates from an upright state to an inverted state, and the adsorption device is activated to adsorb the freeze-dried pellets. Step 3: The first driving device drives the first container to rotate to an upright state, the second driving device ascends, the clamping device releases the first container, and the second driving device drives the first container to descend. Step 4: The first driving device drives the rotating mechanism to move, so that the adsorption device is located above the opening of the second container. The adsorption device is closed. After the freeze-dried pellets are separated from the adsorption device, they fall into the second container, and the dispensing of the freeze-dried pellets is completed.

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