Automated multi-slide preparation and staining device

Abstract

The invention discloses an automated multi-slide preparation and staining device, which belongs to the field of cytopathology diagnosis and comprises a bracket, which comprises a workbench. The automated multi-slide preparation and staining device also comprises a glass slide assembly, a sedimentation bin assembly and a locking structure. The glass slide assembly is located on the workbench, and the glass slide assembly comprises a slide rack and a plurality of slides mounted on the slide rack. The sedimentation bin assembly comprises a mounting plate and a plurality of sedimentation bin bodies mounted on the mounting plate. The locking structure comprises a driving assembly and a clamping block. The driving assembly is mounted on the bracket, and the clamping block is rotatably mounted on the bracket and is transmission-connected with the driving assembly. The clamping block abuts against the mounting plate so that a plurality of sedimentation bin bodies are sealed one-to-one with a plurality of slides. Through the above-mentioned design, a plurality of sedimentation bin bodies can be installed and clamped at the same time, thereby improving work efficiency.

Description

Technical Field

[0001] The invention relates to the field of cytopathology diagnosis, in particular to an automated multi-link slide making and staining device. Background Art

[0002] Pathological diagnosis refers to obtaining human tissues or cells through surgical resection, endoscopic biopsy, fine needle puncture, etc., and using microscopes and other tools to perform a series of processing and observation on the samples to study the causes, pathogenesis, morphological structure, function and metabolism of the disease, reveal the occurrence and development of the disease, and thus clarify the nature of the disease. This is a medical science that is the "gold standard" for the diagnosis of most diseases, especially tumors. Pathological examination includes histological examination and cytological examination, which are the two basic methods of pathological diagnosis, usually called tissue pathology and cytopathology, and mainly conduct morphological observations. By combining with immune diagnosis and molecular diagnosis respectively, pathological diagnosis has formed two other important branches: immunopathology and molecular pathology, which deepen pathological diagnosis from morphological observations at the tissue and cell levels to protein and molecular levels. Modern pathological diagnosis mainly includes histopathology, cytopathology, immunohistochemical pathology and molecular pathology, among which cytopathology occupies a large market share and is the most widely used.

[0003] In pathological diagnosis, slide preparation and staining instruments are often used for sample preparation and staining. Existing slide preparation and staining instruments manually place sedimentation chambers one by one, and manually tighten the sedimentation chambers to achieve the effect of sealing the sedimentation chambers and the glass slides, and then use the automated mechanical arm and the sample injection needle to add the staining solution to achieve the effect of pathological staining. However, when in use, each sample corresponds to a sedimentation chamber, and multiple sedimentation chambers corresponding to multiple samples need to be installed and fixed one by one, which has low production efficiency. Summary of the invention

[0004] In order to overcome the deficiencies of the prior art, one of the purposes of the present invention is to provide an automated multi-unit slide making and staining device capable of installing and fixing multiple sedimentation bins at one time.

[0005] One of the purposes of the present invention is achieved by the following technical solution:

[0006] An automated multi-unit slide making and staining device comprises a bracket, which comprises a workbench. The automated multi-unit slide making and staining device also comprises a glass slide assembly, a sedimentation bin assembly and a locking structure. The glass slide assembly is located on the workbench. The glass slide assembly comprises a glass slide rack and a plurality of glass slides mounted on the glass slide rack. The sedimentation bin assembly comprises a mounting plate and a plurality of sedimentation bin bodies mounted on the mounting plate. The locking structure comprises a driving assembly and a clamping block. The driving assembly is mounted on the bracket. The clamping block is rotatably mounted on the bracket and is transmission-connected to the driving assembly. The clamping block abuts against the mounting plate so that the plurality of sedimentation bin bodies and the plurality of glass slides are sealed one-to-one.

[0007] Furthermore, the driving assembly includes a driving member, a transmission member and a rotating shaft, the driving member is fixed to the bracket, the rotating shaft is rotatably installed on the bracket, the transmission member cooperates with the driving member and the rotating shaft so that the driving member can drive the rotating shaft to rotate, and the clamping block is fixed to the rotating shaft.

[0008] Furthermore, the driving member is a motor.

[0009] Furthermore, the transmission member is a belt.

[0010] Furthermore, the number of the transmission member and the rotating shaft is two, the number of the glass slide assembly and the sedimentation bin assembly is two, and each rotating shaft corresponds to a sedimentation bin assembly.

[0011] Furthermore, the two rotating shafts are parallel to each other.

[0012] Furthermore, the clamping blocks are respectively installed at both ends of the rotating shaft, and the two clamping blocks clamp the two ends of the mounting plate respectively.

[0013] Furthermore, the bracket also includes a positioning pin, which is fixed to the workbench. The mounting plate is provided with a positioning hole, and the positioning pin is located in the positioning hole to position the sedimentation bin assembly.

[0014] Furthermore, the clamping block is L-shaped.

[0015] Furthermore, the workbench is provided with a mounting groove, and the glass slide assembly also includes a plurality of fixing clips, each of which is fixed to the glass slide rack, and the end of each fixing clip abuts against the glass slide so that the plurality of glass slides are mounted on the glass slide rack, and the glass slide rack is located in the mounting groove.

[0016] Compared with the prior art, the slide assembly of the automated multi-unit slide making and staining device of the present invention includes a slide rack and a plurality of slides mounted on the slide rack, the sedimentation bin assembly includes a mounting plate and a plurality of sedimentation bin bodies mounted on the mounting plate, the locking structure includes a driving assembly and a clamping block, the driving assembly is mounted on a bracket, the clamping block is rotatably mounted on the bracket and is transmission-connected to the driving assembly, the clamping block abuts against the mounting plate so that a plurality of sedimentation bin bodies are sealed one-to-one with a plurality of slides, and through the above-mentioned design, a plurality of sedimentation bin bodies can be installed and clamped at the same time, thereby improving work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a three-dimensional diagram of the automatic multi-link slide making and staining device of the present invention;

[0018] Figure 2 for Figure 1 A partial structural exploded view of the automated multi-unit slide preparation and staining device;

[0019] Figure 3 for Figure 1 A three-dimensional diagram of a support of an automated multi-link slide preparation and staining device;

[0020] Figure 4 for Figure 1 A three-dimensional diagram of a mounting plate of an automated multi-link slide preparation and staining device;

[0021] Figure 5 for Figure 1 Partial structural assembly diagram of the automated multi-unit slide preparation and staining device.

[0022] In the figure: 10, bracket; 11, workbench; 110, mounting groove; 111, receiving groove; 12, side plate; 13, support plate; 130, weight reduction hole; 14, positioning pin; 20, glass slide assembly; 21, slide rack; 22, fixing clamp; 23, slide; 230, identification mark; 30, sedimentation bin assembly; 31, sedimentation bin body; 32, mounting plate; 320, plate body; 321, mounting hole; 322, fixing protrusion; 323, positioning hole; 40, locking structure; 41, drive assembly; 410, drive member; 411, transmission member; 413, rotating shaft; 42, clamping block; 43, mounting assembly; 430, fixing frame; 431, bearing; 50, staining assembly; 51, fixing block; 52, staining needle. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] It should be noted that when a component is referred to as being "fixed to" another component, it may be directly on the other component or there may be another intermediate component through which it is fixed. When a component is considered to be "connected to" another component, it may be directly connected to the other component or there may be another intermediate component at the same time. When a component is considered to be "set on" another component, it may be directly set on the other component or there may be another intermediate component at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only.

[0025] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0026] like Figures 1 to 5 As shown, the automated multi-unit slide making and staining device of the present invention comprises a support 10, a slide assembly 20, a sedimentation chamber assembly 30, a locking structure 40 and a staining assembly 50.

[0027] The bracket 10 includes a workbench 11, a side panel 12, a support panel 13 and a positioning pin 14. The workbench 11 is provided with a mounting groove 110 and a receiving groove 111. The shape of the mounting groove 110 corresponds to the shape of the glass slide assembly 20 so as to mount the glass slide assembly 20. Specifically, there are two mounting grooves 110, and the two mounting grooves 110 are symmetrically arranged. The mounting groove 110 is a groove. The receiving groove 111 is located at the side of the mounting groove 110, and the clamping block 42 is partially located in the receiving groove 111 and can rotate in the receiving groove 111. Specifically, there are four receiving grooves 111, and the four receiving grooves 111 are respectively located on both sides of the two mounting grooves 110. The receiving groove 111 is a through groove. The side panel 12 is fixedly connected to the workbench 11, and the workbench 11 is located at the top of the side panel 12 and is perpendicular to the side panel 12. The side panel 12 is used to fix the driving assembly 41 of the locking structure 40. The support plate 13 is fixedly connected to the workbench 11, and the workbench 11 is located on the top of the support plate 13 and is perpendicular to the support plate 13. The support plate 13 is perpendicular to the side plate 12. The support plate 13 is provided with a weight-reducing hole 130, which reduces the weight of the bracket 10 while ensuring the structural strength of the support plate 13, so as to make the bracket 10 lightweight.

[0028] The glass slide assembly 20 includes a glass slide rack 21, a fixing clamp 22 and a glass slide 23. The glass slide rack 21 is provided with a mounting position, and the number of the fixing clamps 22 and the glass slides 23 is the same. One end of the fixing clamp 22 is fixed to the glass slide rack 21, and the glass slide 23 is placed on the glass slide rack 21. The other end of the fixing clamp 22 abuts against the glass slide 23, so that the glass slide 23 is clamped on the glass slide rack 21. Each glass slide 23 is provided with an identification mark 230, and the identification mark 230 is one of text, pattern, color block, and QR code. Specifically, in the present embodiment, the identification mark 230 is a QR code, and the QR code contains various information of the sample. In the present embodiment, the number of glass slide assemblies 20 is two, and the two glass slide assemblies 20 are arranged in parallel.

[0029] The sedimentation bin assembly 30 includes a plurality of sedimentation bin bodies 31 and a mounting plate 32. The number of the sedimentation bin bodies 31 is the same as the number of the slides 23. The mounting plate 32 includes a plate body 320 and a fixing protrusion 322, and the two fixing protrusions 322 extend from both ends of the plate body 320. Each fixing protrusion 322 is provided with a positioning hole 323. The plate body 320 is provided with a plurality of mounting holes 321, and the number of the mounting holes 321 is the same as the number of the sedimentation bin bodies 31, and each mounting hole 321 is installed with a sedimentation bin body 31.

[0030] The locking structure 40 includes a driving assembly 41 , a clamping block 42 and a mounting assembly 43 .

[0031] The driving assembly 41 includes a driving member 410, a transmission member 411 and a rotating shaft 413. The driving member 410 is fixed to the side plate 12 of the bracket 10. Specifically, the driving member 410 is a motor. The transmission member 411 transmits the power of the driving member 410 to the rotating shaft 413, so that the driving member 410 drives the rotating shaft 413 to rotate. The transmission member 411 is any one of a synchronous belt, a gear set, and a gear rack. The rotating shaft 413 is rotatably mounted on the two side plates 12 of the bracket 10. In the present embodiment, the transmission member 411 is a synchronous belt, and the synchronous belt is sleeved on the output end of the driving member 410 and the rotating shaft 413. In the present embodiment, the number of the rotating shafts 413 is two, and the two rotating shafts 413 are arranged in parallel.

[0032] The clamping block 42 is rotatably mounted on the side plate 12 of the bracket 10. The clamping block 42 is fixed to the end of the rotating shaft 413. In this embodiment, there are four clamping blocks 42, and the four clamping blocks 42 are respectively located in the receiving grooves 111 at both ends of the two installation grooves 110. The clamping block 42 is L-shaped.

[0033] The mounting assembly 43 includes a fixing frame 430 and a bearing 431 . The fixing frame 430 is fixed to the side plate 12 , and the clamping block 42 is rotatably mounted on the fixing frame 430 via the bearing 431 .

[0034] The dyeing assembly 50 includes a fixing block 51 and a dyeing needle 52 . There are multiple dyeing needles 52 , and the multiple dyeing needles 52 are fixed to one side of the fixing block 51 .

[0035] When using the automated multi-unit slide preparation and staining device, the carrier gripper places the glass slide assembly 20 on the workbench 11 of the bracket 10. Then the sedimentation chamber assembly 30 is grabbed and placed on the glass slide assembly 20. At this time, the positioning hole 323 of the sedimentation chamber assembly 30 moves to above the positioning pin 14, and the sedimentation chamber assembly 30 moves downward, so that the positioning hole 323 moves along the positioning pin 14, and the sedimentation chamber assembly 30 is positioned. The driving member 410 drives the rotating shaft 413 to rotate, and the rotating shaft 413 drives the clamping block 42 to rotate. The end of the clamping block 42 contacts the fixed protrusion 322 of the sedimentation chamber assembly 30, so that the sedimentation chamber assembly 30 contacts the glass slide assembly 20, and the sedimentation chamber body 31 is sealed with the slide 23.

[0036] Through the above design, the automated multi-unit slide making and staining device can simultaneously install and clamp multiple sedimentation bin bodies 31, thereby improving work efficiency.

[0037] The above embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the present invention, which are equivalent modifications and improvements made to the above embodiments based on the essential technology of the present invention, and all of them belong to the protection scope of the present invention.

Claims

1. An automated multi-unit slide preparation and staining device, comprising a support, wherein the support comprises a workbench, characterized in that: The automated multi-unit slide preparation and staining device further comprises a glass slide assembly, a sedimentation chamber assembly, a locking structure and a staining assembly, wherein the glass slide assembly is located on the workbench, the glass slide assembly comprises a glass slide rack and a plurality of glass slides mounted on the glass slide rack, the sedimentation chamber assembly comprises a mounting plate and a plurality of sedimentation chamber bodies mounted on the mounting plate, the bottoms of the plurality of sedimentation chamber bodies are mounted on the mounting plate, the staining assembly comprises a fixed block and a plurality of staining needles fixed on the fixed block, the locking structure comprises a driving assembly and a clamping block, the driving assembly is mounted on the bracket, and the clamping block is rotatably mounted on the bracket. The bracket is in driving connection with the driving assembly, the clamping block abuts against the mounting plate so that the multiple sedimentation bin bodies and the multiple slides are sealed one by one, the driving assembly comprises a driving member, a transmission member and a rotating shaft, the driving member is fixed to the bracket, the rotating shaft is rotatably installed on the bracket, the transmission member cooperates with the driving member and the rotating shaft so that the driving member can drive the rotating shaft to rotate, the clamping block is fixed to the rotating shaft, the number of the transmission member and the rotating shaft is two, the number of the glass slide assemblies and the sedimentation bin assemblies is two, and each rotating shaft corresponds to one sedimentation bin assembly.

2. The automated multi-unit slide making and staining device according to claim 1, characterized in that: The driving member is a motor.

3. The automated multi-unit slide making and staining device according to claim 1, characterized in that: The transmission member is a belt.

4. The automated multi-unit slide making and staining device according to claim 1, characterized in that: The two rotating shafts are parallel to each other.

5. The automated multi-unit slide making and staining device according to any one of claims 2 to 3, characterized in that: The two ends of the rotating shaft are respectively installed with the clamping blocks, and the two clamping blocks clamp the two ends of the mounting plate respectively.

6. The automated multi-unit slide making and staining device according to any one of claims 1 to 3, characterized in that: The bracket also includes a positioning pin, which is fixed to the workbench. The mounting plate is provided with a positioning hole, and the positioning pin is located in the positioning hole to position the sedimentation bin assembly.

7. The automated multi-unit slide making and staining device according to any one of claims 1 to 3, characterized in that: The clamping block is L-shaped.

8. The automated multi-unit slide making and staining device according to any one of claims 1 to 3, characterized in that: The workbench is provided with a mounting groove, and the glass slide assembly also includes a plurality of fixing clips, each of which is fixed to the glass slide rack, and the end of each fixing clip abuts against the glass slide so that the plurality of glass slides are mounted on the glass slide rack, and the glass slide rack is located in the mounting groove.

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