COPD electrode catheter

Abstract

The application belongs to the technical field of medical devices, and particularly relates to a COPD electrode catheter, which comprises a braided mesh basket structure and a sleeve; the braided mesh basket structure has a hollow cavity communicating with a distal end and a proximal end; the COPD electrode catheter further comprises: a middle core rod penetrating through the hollow cavity of the braided mesh basket structure; a distal end fixing assembly fixing the distal end of the braided mesh basket structure and the distal end of the middle core rod; and a proximal end fixing assembly fixing the proximal end of the braided mesh basket structure at the distal end of the sleeve. The distal end fixing assembly and the proximal end fixing assembly cooperate to fix the braided mesh basket structure and the middle core rod, the braided mesh basket structure does not twist, and after being released, the braided mesh basket structure can stably expand to a preset diameter, thereby further improving the stability of the pulse field ablation COPD operation.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to a COPD electrode catheter. BACKGROUND

[0002] Chronic obstructive pulmonary disease (COPD) refers to chronic lung diseases that cause airflow limitation in the lungs. COPD is progressive and irreversible; it is mainly caused by the proliferation of part of the cells in the lung airway due to external stimulation, and the proliferated cells secrete more mucus in order to expel the external stimulus through the mucus, while the excessive cell proliferation and excessive mucus production further reduce the size of the lung airway, and make the respiratory difficulty further intensified.

[0003] Pulse field ablation (PFA) is a technology that uses high-voltage discharge to cause irreversible electroporation of cells, which can directly act on cells to cause apoptosis to achieve the purpose of treatment. The irreversible electroporation ablation technology used by pulse field ablation is a non-heating ablation technology, which can selectively break cells by adjusting the size of the voltage, without affecting the surrounding tissues, and without tissue scabbing phenomenon during and after the operation, so as to not affect the normal function of the lung airway. In addition, the mechanism of cell death caused by irreversible electroporation is apoptosis, not necrosis. The advantage of cell apoptosis is that the apoptotic cells are removed by immune intervention, and the phagocytic cells remove the apoptotic cells as a normal cell death process to promote the regeneration and repair of normal tissues, so that the treatment area can be replaced by normal cells in a short time after irreversible electroporation treatment to restore the original function.

[0004] At present, pulse field ablation COPD generally applies voltage between a single electrode catheter and a back electrode plate to implement ablation on the lung airway. The single electrode catheter is mostly of a woven basket structure, but since the distal end and the proximal end of the woven basket are respectively fixed on different structures, when the sleeve connected to the proximal end of the basket is rotated, the basket will be twisted, and the twisted basket cannot be inflated to the predetermined diameter as required. This phenomenon is not expected to occur during the operation, otherwise it will lead to the failure of the operation. SUMMARY

[0005] The present application aims at the technical problem that the woven basket structure in the existing design is prone to twisting, which leads to the failure to expand to the preset size, and provides a COPD electrode catheter.

[0006] A COPD electrode catheter, comprising an electrode and a sleeve, wherein the electrode adopts a woven basket structure;

[0007] The woven basket structure has a hollow cavity communicating with the distal end and the proximal end;

[0008] The COPD electrode catheter further comprises:

[0009] a middle core rod passing through the hollow cavity of the braided basket structure;

[0010] a distal end fixing assembly fixing the distal end of the braided basket structure and the distal end of the middle core rod;

[0011] a proximal end fixing assembly fixing the proximal end of the braided basket structure at the distal end of the sleeve;

[0012] wherein the sleeve and the proximal end fixing assembly are axially movable relative to the middle core rod, and the proximal end fixing assembly restricts the sleeve from rotating relative to the middle core rod, so as to make the braided basket structure contract or expand to a predetermined state.

[0013] As a preferred solution, the distal end fixing assembly comprises:

[0014] a protruding ring fixed internally at the distal end of the middle core rod;

[0015] a fixing cap with an open proximal end surface, the fixing cap being sleeved outside the protruding ring, and the distal end of the braided basket structure being clamped between the fixing cap and the protruding ring.

[0016] As a preferred solution, the fixing cap is uniformly provided with a plurality of guide grooves along the circumference, and the length direction of the guide grooves is the axial direction.

[0017] The distal end of the braided basket structure is uniformly arranged in the plurality of guide grooves.

[0018] As a preferred solution, the depth of the guide grooves is less than the diameter of the braided wire of the braided basket structure.

[0019] As a preferred solution, the proximal end fixing assembly comprises:

[0020] an inner fixing ring sleeved outside the middle core rod and axially movable along the middle core rod;

[0021] an outer fixing ring sleeved outside the inner fixing ring, and the proximal end of the braided basket structure being clamped between the outer fixing ring and the inner fixing ring.

[0022] The sleeve comprises:

[0023] an outer tube, the distal end of the outer tube being sleeved outside the outer periphery of the outer fixing ring and fixed with the outer fixing ring.

[0024] As a preferred solution, the inner diameter of the inner fixing ring: the diameter of the middle core rod = 1.1-1.3.

[0025] As a preferred solution, the inner diameter of the outer tube: the outer diameter of the outer fixing ring = 0.9-1.0.

[0026] As a preferred solution, the sleeve further comprises:

[0027] an inner tube, which is arranged in the outer tube and sleeved on the middle core rod, and the distal end of the inner tube abuts against the proximal end of the outer fixing ring.

[0028] As a preferred solution, the outer diameter of the inner tube is the same as the outer diameter of the outer fixing ring.

[0029] As a preferred solution, the outer tube is a nylon elastic tube made of PEBAX (modified nylon) material.

[0030] As a preferred solution, the middle core rod is of a solid structure, and the middle core rod is made of nickel-titanium alloy.

[0031] As a preferred solution, the middle core rod is a conductor, and the distal end of the braided basket structure and / or the proximal end of the braided basket structure is in conductive connection with the middle core rod, so that the pulse ablation energy can be transmitted to the braided basket structure.

[0032] As a preferred solution, the middle core rod is a conductor, and at least one of the convex ring and the inner fixing ring is a conductor.

[0033] As a preferred solution, the diameter of the middle core rod is 0.4mm-0.8mm, preferably 0.5mm or 0.6mm.

[0034] The positive progress effect of the present application is that the COPD electrode catheter has the following beneficial effects:

[0035] 1. The braided basket structure and the middle core rod are fixed through the cooperative action of the distal end fixing assembly and the proximal end fixing assembly, and the existence of the proximal end fixing assembly limits the rotation of the sleeve, so that the sleeve cannot easily rotate relative to the middle core rod, but only moves in the axial direction, so that the braided basket structure will not be twisted, and after being released, the braided basket structure can be stably expanded to the preset diameter, further improving the stability of the pulse field ablation COPD operation.

[0036] 2. The guide groove in the fixing cap can guide the braided wire, avoiding the influence of the uneven distribution of the braided wire on the mesh size and uniformity of the braided basket structure during the process of being bundled. The depth of the guide groove is less than the diameter of the braided wire, so as to increase the friction between the braided wire and the convex ring and improve the stability of the fixing of the braided basket structure.

[0037] 3. An inner tube is installed inside the outer tube. This serves two purposes: firstly, to fill the large gap between the outer tube and the central core rod caused by the inner and outer fixing rings, ensuring the central core rod maintains its centering during movement and preventing bending; secondly, the inner tube supports the outer tube, reducing excessive local stress caused by the interference fit between the outer fixing ring and the outer tube, thus preventing damage to the outer tube during use due to excessive local stress. Simultaneously, the inner tube's filling ensures that the central core rod can only move axially relative to the outer tube, further restricting the rotation of the outer tube and making the entire structure more stable.

[0038] 4. The woven basket structure, as a single electrode, can be electrically connected to the woven basket structure directly through the core rod itself, or indirectly through the raised ring or the inner fixing ring.

[0039] 5. The woven basket structure has a mesh structure with both ends converging and the middle part being a hollow cylinder in the expanded state. The converging sections at both ends can maintain a fixed state with the distal and proximal fixation components, and the hollow cylinder in the middle has the characteristic of a large ablation area, resulting in good pulse field ablation effect for COPD.

[0040] 6. The design of the size, mesh density, number of braided filaments, braiding method, and concave state when the braided basket structure is closed allows the braided basket structure to achieve good closure and expand to the preset size after release, without affecting the pulse field ablation COPD surgery.

[0041] 7. The surface of the nickel-titanium braided wire does not contain an oxide layer. That is, in the nickel-titanium alloy, Ni and Ti exist in an atomic state, which can greatly improve the electrical conductivity of the braided basket structure and promote the electroporation effect of tissue cells. Attached Figure Description

[0042] Figure 1(a) is a schematic diagram of an application of the present invention;

[0043] Figure 1(b) is a partial schematic diagram of Figure 1(a);

[0044] Figure 2 This is a schematic diagram of one structure of the present invention;

[0045] Figure 3 for Figure 2 Internal sectional view;

[0046] Figure 4 for Figure 3 A magnified view of a section at point A in the middle;

[0047] Figure 5 for Figure 3 A magnified view of a section at point B in the middle;

[0048] Figure 6The connection relationship diagram between the braided mesh basket structure, the middle core rod and the distal end fixing assembly of the application;

[0049] Figure 7 The structure diagram of the fixed cap of the application;

[0050] Figure 8 The braiding method of the braided mesh basket structure of the application;

[0051] Figure 9 The state diagram of the braided mesh basket structure of the application when being gathered. DETAILED DESCRIPTION

[0052] In order to make the technical means, creative features, purposes and effects of the application easy to understand, the application will be further described below in combination with specific diagrams.

[0053] In the application, when describing the COPD electrode catheter, "distal end", "proximal end", "distal segment" and "proximal segment" are used as orientation words, which are common terms in the field of interventional medical devices. The "distal end" and "distal segment" represent the end or segment far away from the operator during the operation, and the "proximal end" and "proximal segment" represent the end or segment close to the operator during the operation. "Axial direction" refers to the direction parallel to the connecting line between the center of the distal end and the center of the proximal end of the medical device; "radial direction" refers to the direction perpendicular to the "axial direction".

[0054] Referring to FIGS. 1(a) and 1(b), the COPD electrode catheter of the application is applied to an ablation electrode catheter device as a part of the ablation electrode catheter device, which includes the COPD electrode catheter 100 of the application and a catheter handle 200. The distal end of the catheter handle 200 is connected with the COPD electrode catheter 100, the catheter handle 200 drives the COPD electrode catheter 100 to move towards the proximal end or the distal end, and the catheter handle 200 supplies power to the COPD electrode catheter 100. The catheter handle 200 can adopt any handle in the prior art that can achieve the above-mentioned functions of moving the COPD electrode catheter 100 and supplying power to the COPD electrode catheter 100, which will not be described here in detail.

[0055] Referring to Figure 2 and Figure 3 , the COPD electrode catheter 100 includes a braided mesh basket structure 110, a middle core rod 120, a distal end fixing assembly 130, a proximal end fixing assembly 140 and a sleeve.

[0056] The braided basket structure 110 is an electrode of the COPD electrode catheter of the present application, also referred to as a single electrode, and has a hollow cavity communicating with the distal end and the proximal end, through which the middle core rod 120 passes, so as to fix the distal end of both through the distal end fixing assembly 130, and to limit the rotation of the braided basket structure 110 relative to the middle core rod 120 through the proximal end fixing assembly 140. Specifically, the sleeve and the proximal end fixing assembly 140 can move axially relative to the middle core rod 120, and the proximal end fixing assembly 140 limits the rotation of the sleeve relative to the middle core rod, so as to make the braided basket structure 110 contract or expand to a predetermined state.

[0057] The present application fixes the braided basket structure 110 and the middle core rod 120 through the cooperation of the distal end fixing assembly 130 and the proximal end fixing assembly 140, and the presence of the proximal end fixing assembly 140 limits the rotation of the sleeve, so that the sleeve does not easily rotate relative to the middle core rod 120, but only moves in the axial direction, so that the braided basket structure 110 does not twist, and after being released, can stably expand to a preset diameter, further improving the stability of the pulsed field ablation COPD operation. Optionally, as a further improvement of the present application, the inner fixing ring 141 of the proximal end fixing assembly 140 and the middle core rod 120 can be provided with a clamping protrusion structure, for example, an axially extending clamping boss or clamping groove is provided on the outer surface of the middle core rod 120, and a corresponding axially extending clamping groove or clamping boss is provided on the inner fixing ring 141, so as to limit the rotation of the sleeve relative to the middle core rod 140. It can also be that the middle core rod 140 is provided in an irregular shape other than a circle, and a passage is provided in the sleeve to match the outer shape of the middle core rod 140, so that the outer tube only moves axially.

[0058] In some embodiments, referring to Figure 3 , Figure 4 and Figure 6 , the distal end fixing assembly 130 includes a protruding ring 131 and a fixing cap 132. The distal end of the middle core rod 120 is inserted into the protruding ring 131, and the inside of the protruding ring 131 is fixed with the distal end of the middle core rod 120. The proximal end of the fixing cap 132 is open, the fixing cap 132 is sleeved outside the protruding ring 131, and the distal end of the braided basket structure 110 is clamped between the fixing cap 132 and the protruding ring 131. The distal end of the braided basket structure 110 is bundled through the sleeving of the fixing cap 132 and the protruding ring 131.

[0059] In some embodiments, referring to Figure 7The fixed cap 132 is provided with a plurality of guide grooves 1321 uniformly distributed in the circumferential direction, and the length direction of the guide grooves 1321 is the axial direction. The distal end of the woven mesh basket structure 110 is uniformly arranged in the plurality of guide grooves 1321. The bundled woven wires of the distal end of the woven mesh basket structure 110 can be single or multiple stacked in the same guide groove 1321. When the number of woven wires is small, a single woven wire is preferably arranged in the corresponding single guide groove 1321, and the multiple woven wires are independent of each other.

[0060] The guide grooves 1321 in the fixed cap 132 of the present application can guide the woven wires, avoiding the uneven distribution of the woven wires during the bundling process, which affects the mesh size and uniformity of the woven mesh basket structure 110.

[0061] In some embodiments, referring to Figure 6 The depth of the guide groove 1321 is less than the diameter of the woven wire of the woven mesh basket structure 110. The friction between the woven wire and the protruding ring 131 is increased, and the stability of the fixed woven mesh basket structure 110 is improved.

[0062] In some embodiments, referring to Figure 3 and Figure 5 The proximal end fixing assembly 140 includes an inner fixing ring 141 and an outer fixing ring 142. The inner fixing ring 141 is sleeved outside the middle core rod 120, and the inner fixing ring 141 can move axially along the middle core rod 120. The outer fixing ring 142 is sleeved outside the inner fixing ring 141, and the proximal end of the woven mesh basket structure 110 is clamped between the outer fixing ring 142 and the inner fixing ring 141. The proximal end of the woven mesh basket structure 110 is clamped between the outer fixing ring 142 and the inner fixing ring 141. The inner fixing ring 141 is tightly fitted with the middle core rod 120, so that the inner fixing ring 141 does not rotate with the outer tube 151 when the outer tube 151 and the middle core rod 120 rotate relatively, thereby avoiding the twisting of the woven mesh basket structure 110.

[0063] The sleeve pipe includes an outer tube 151, and the distal end of the outer tube 151 is fixed with the proximal end fixing assembly 140. The outer tube 151 can be connected with the catheter handle 200, and the catheter handle 200 drives the woven mesh basket structure 110 to move to the distal end or the proximal end through the outer tube 151, or rotates.

[0064] In some embodiments, the inner fixing ring 141 can be sleeved on the outer periphery of the middle core rod 120 to avoid rotation of the inner fixing ring 141 with the outer tube 142 by setting the middle core rod 120 into an irregular cylindrical structure, or a prism, or an elliptical structure, or other structures. Alternatively, the matching part of the inner fixing ring 141 and the middle core rod 120 can be set as a clamping protrusion structure, a protrusion or a groove is set on the middle core rod 120, and a corresponding groove or protrusion is set on the inner fixing ring 141 to limit rotation of the inner fixing ring 141 along the axis of the middle core rod 120.

[0065] In some embodiments, the inner diameter of the inner fixing ring 141: the diameter of the middle core rod 120 = 1.1-1.3. This can enable the middle core rod 120 to pass through the inner fixing ring 141 more smoothly.

[0066] In some embodiments, the inner diameter of the outer tube 151: the outer diameter of the outer fixing ring 142 = 0.9-1.0. This can enable the outer tube 151 and the outer fixing ring 142 to be fixed by interference fit.

[0067] In some embodiments, the sleeve further includes an inner tube 152, which is arranged in the outer tube 151 and sleeved on the middle core rod 120, and the distal end of the inner tube 152 abuts against the proximal end of the outer fixing ring 142. The inner tube 152 is arranged in the inner part of the outer tube 151, which can fill the large gap between the outer tube 151 and the middle core rod 120 caused by the inner and outer fixing rings 142, so that the middle core rod 120 always maintains centricity during movement and avoids bending. On the other hand, the inner tube is used to support the outer tube 151 to reduce the local stress caused by the interference fit between the outer fixing ring 142 and the outer tube 151, thereby avoiding damage to the outer tube 151 caused by excessive local stress during use. At the same time, the inner tube 152 fills the gap between the outer tube 151 and the middle core rod 120 to increase the radial rotation resistance of the middle core rod 120, further limit the rotation of the outer tube 151, and make the entire structure more stable. Alternatively, the outer tube 151 at the fixed part of the proximal end fixing assembly 140 can be set as a stepped structure, i.e., the inner diameter of the outer tube 151 at the fixed part of the proximal end fixing assembly 140 matches the outer diameter of the outer fixing ring 142, and the inner diameter of the outer tube 151 at the part other than the proximal end fixing assembly 140 matches the outer shape of the middle core rod 120. This structure can also limit the rotation of the outer tube 151.

[0068] In some embodiments, the outer diameter of the inner tube 152 is the same as the outer diameter of the outer fixing ring 142.

[0069] In some embodiments, the outer tube 151 is a nylon elastic tube made of PEBAX (modified nylon) material. This can enable the outer tube 151 to have a certain degree of bending to facilitate entry into the target position in the body. The outer wall of the outer tube 151 should be smooth without burrs to avoid damage to internal human tissues.

[0070] In some embodiments, the middle core rod 120 is a solid structure, which can enhance the support strength of the middle core rod 120. The middle core rod 120 is made of nickel-titanium alloy. The surface of the middle core rod 120 can be removed of the oxide layer or not. When the middle core rod 120 serves as a conductor to supply power to the braided basket structure 110, the surface of the middle core rod 120 is removed of the oxide layer to improve the conductivity.

[0071] In some embodiments, the middle core rod 120 is a conductor, and the distal end of the braided basket structure 110 and / or the proximal end of the braided basket structure 110 is in conductive connection with the proximal end of the middle core rod 120. That is, the distal end of the braided basket structure 110 and the distal end of the middle core rod 120 are in conductive connection with each other, or the proximal end of the braided basket structure 110 and the proximal end of the middle core rod 120 are in conductive connection with each other, or the distal end of the braided basket structure 110 and the distal end of the middle core rod 120 are in conductive connection with each other and the proximal end of the braided basket structure 110 and the proximal end of the middle core rod 120 are in conductive connection with each other. The connection between the two can be fastened by a fastener, such as a copper wire wrapped around the proximal end side of the distal end fixing assembly 130 or the distal end side of the proximal end fixing assembly 140 to achieve electrical connection.

[0072] When the braided basket structure 110 in the above-mentioned manner serves as a single electrode, the middle core rod 120 itself is directly connected to the braided basket structure 110 for power supply, so that the pulsed ablation energy can be transmitted to the braided basket structure 110.

[0073] The middle core rod 120 and the outer tube 151 passing through the inner fixing ring 141 are respectively connected to the catheter handle 200, the outer tube 151 is rotated by the catheter handle 200, and the middle core rod 120 is powered by the catheter handle 200.

[0074] In some embodiments, the middle core rod 120 is a conductor, and at least one of the protruding ring 131 and the inner fixing ring 141 is a conductor. That is, the protruding ring 131 is a conductor, or the inner fixing ring 141 is a conductor, or both the protruding ring 131 and the inner fixing ring 141 are conductors.

[0075] When the braided basket structure 110 in the above-mentioned manner serves as a single electrode, the middle core rod 120 is indirectly powered through the protruding ring 131 or through the inner fixing ring 141.

[0076] The power supply mode of the braided basket structure 110 is not limited to the above-mentioned direct or indirect power supply mode, as long as the braided basket structure 110 can be powered through the catheter handle 200. For example, an axial power supply through hole is formed in the middle core rod 120, a wire is connected to the braided basket structure 110 after passing through the power supply through hole and being pulled out from the catheter handle 200, and the middle core rod 120 is an insulator at this time.

[0077] In some embodiments, the diameter of the middle core rod is 0.4-0.8mm, preferably 0.5mm or 0.6mm.

[0078] In some embodiments, the braided mesh basket structure 110 generally has an expanded state and a collapsed state, referring to Figure 2 and Figure 3 , the braided mesh basket structure 110 of the present application is in the expanded state. Referring to Figure 9 , the braided mesh basket structure 110 of the present application is in the collapsed state.

[0079] In some embodiments, referring to Figure 2 , in the expanded state, the braided mesh basket structure 110 sequentially includes a first constriction section 111, a hollow cylindrical section 112 and a second constriction section 113 connected integrally from distal end to proximal end. The distal end of the first constriction section 111 is fixed with the distal end fixing assembly 130, and the first constriction section 111 adopts a hollow circular truncated cone structure with a larger proximal end diameter than a distal end diameter. The proximal end of the second constriction section 113 is fixed with the proximal end fixing assembly 140, and the second constriction section 113 adopts a hollow circular truncated cone structure with a larger distal end diameter than a proximal end diameter. The openings of the first constriction section 111 and the second constriction section 113 are oppositely arranged and both face the hollow cylindrical section 112. The braided mesh basket structure 110 of the present application is a mesh structure with two ends constricted and a middle part as a hollow cylinder in the expanded state. The two end constriction sections can better maintain a fixed state with the distal end fixing assembly 130 and the proximal end fixing assembly 140. The hollow cylinder in the middle part has the characteristics of a larger ablation area, and the pulsed field ablation COPD effect is good.

[0080] In some embodiments, the axial length of the first constriction section 111 is greater than the axial length of the second constriction section 113, and the axial length of the first constriction section 111: the axial length of the hollow cylindrical section 112 = 1:1-3, preferably 1:1.2-2.5, such as 1:1.5, 1:1.8 or 1:2.2, etc.

[0081] In some embodiments, the axial length of the braided mesh basket structure 110: the diameter of the hollow cylindrical section 112 = 1.05-1.8, preferably 1.1-1.6, such as 1.2, 1.3, 1.5 or 1.7, etc.

[0082] In some embodiments, the braided mesh basket structure 110 is a mesh basket structure with mesh holes formed by braiding wires. When the diameter of the hollow cylindrical section 112 is 15-22mm, the mesh density PPI of the braided mesh basket structure 110 is 20-28, preferably 22-26, such as 23, 24 or 25, etc. Among them, the mesh density PPI refers to the number of mesh holes per unit length (inch) when the braided mesh basket structure 110 is produced and prepared.

[0083] In some embodiments, referring to Figure 8 The woven mesh basket structure 110 has two groups of woven groups, each group of woven groups has a plurality of woven wires. For example, each group of woven groups has 16-20 woven wires. The woven wires in the two groups of woven groups are cross-woven to form diamond-shaped mesh holes with diamond-shaped structures. The two inner angles a of the diamond-shaped mesh holes along the axial direction are preferably 45°-75°. That is, the diamond-shaped mesh holes are more easily stretched in the axial direction than in the radial direction.

[0084] In the weaving process, the adjacent woven wires in a single group of woven groups are arranged substantially in parallel and have no weaving intersection points with each other. Any two woven wires in the two groups of woven groups are not parallel to each other, achieving the purpose of cross-weaving.

[0085] For example, a single diamond-shaped mesh hole is formed by the adjacent woven wire a1 and the woven wire a2 in one group of woven groups and the adjacent woven wire b1 and the woven wire b2 in the other group of woven groups, respectively.

[0086] In some embodiments, the weaving method of the present application adopts a press-and-weave method, that is, two different groups of woven wires cross to form a weaving intersection point, and a single woven wire is arranged alternately above and below at the positions of its adjacent two weaving intersection points. As shown in Figure 8 For example, the woven wire a1 crosses the woven wire b1 and the woven wire b2 to form adjacent weaving intersection points o1 and o2, respectively. The woven wire a1 at the weaving intersection point o1 is located above the woven wire b1, and the woven wire a1 at the weaving intersection point o2 is located below the woven wire b2. Similarly, when the woven wire b1 at the weaving intersection point o1 is located below, the woven wire b1 is located above at the other two weaving intersection points adjacent to the weaving intersection point o1.

[0087] In some embodiments, the wire diameter of the woven wire is 0.05 mm-0.15 mm, preferably 0.07 mm-0.12 mm, such as 0.08 mm, 0.09 mm, 0.10 mm, or 0.11 mm, etc.

[0088] In some embodiments, the woven wire is a nickel-titanium alloy, and the woven wire is an electrically conductive woven wire without an oxidation layer on the surface. The nickel-titanium woven wire has no oxidation layer on the surface, that is, Ni and Ti exist in the form of atoms in the nickel-titanium alloy, which can greatly improve the electrical conductivity of the woven mesh basket structure and promote the electroporation effect of the tissue cells.

[0089] In some embodiments, referring to Figure 9 In the collapsed state, the middle part of the woven mesh basket structure 110 is inwardly recessed to the side of the middle core rod 120, and the inner wall of the woven mesh basket structure 110 has a predetermined distance from the middle core rod 120. The woven mesh basket structure 110 in the collapsed state is not in contact with the middle core rod 120.

[0090] The above shows and describes the basic principles, main features and advantages of the present application. Those skilled in the art should understand that the present application is not limited to the above-mentioned embodiments, and the above-mentioned embodiments and descriptions in the specification are only to illustrate the principles of the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the claimed present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A COPD electrode catheter, comprising an electrode and a sleeve, the electrode adopting a braided mesh basket structure; characterized in that the braided mesh basket structure has a hollow cavity communicating with a distal end and a proximal end; the COPD electrode catheter further comprises: a middle core rod passing through the hollow cavity of the braided mesh basket structure; a distal end fixing assembly fixing the distal end of the braided mesh basket structure and the distal end of the middle core rod, the distal end fixing assembly comprising: a protruding ring fixed internally with the distal end of the middle core rod; a fixing cap with an open proximal end surface, the fixing cap being sleeved outside the protruding ring, and the distal end of the braided mesh basket structure being clamped between the fixing cap and the protruding ring; a proximal end fixing assembly fixing the proximal end of the braided mesh basket structure at the distal end of the sleeve, the proximal end fixing assembly comprising: an inner fixing ring sleeved outside the middle core rod and axially movable along the middle core rod; an outer fixing ring sleeved outside the inner fixing ring, the outer fixing ring and the inner fixing ring clamping the proximal end of the braided mesh basket structure therebetween; the sleeve comprising: an outer tube, the distal end of the outer tube being sleeved on the outer periphery of the outer fixing ring and fixed with the outer fixing ring; wherein the sleeve and the proximal end fixing assembly are axially movable relative to the middle core rod, the proximal end fixing assembly limiting the sleeve from rotating relative to the middle core rod, so that the braided mesh basket structure is contracted or expanded to a predetermined state, and the inner diameter of the outer tube: the outer diameter of the outer fixing ring = 0.9-1.

0.

2. The COPD electrode catheter of claim 1, wherein, a plurality of guide grooves are uniformly arranged circumferentially in the fixing cap, the length direction of the guide grooves being the axial direction; the distal end of the braided mesh basket structure is uniformly arranged in the plurality of guide grooves.

3. The COPD electrode catheter of claim 2, wherein, the depth of the guide grooves is less than the diameter of the braided wire of the braided mesh basket structure.

4. The COPD electrode catheter of claim 1, wherein, the inner diameter of the inner fixing ring: the diameter of the middle core rod = 1.1-1.

3.

5. The COPD electrode catheter of claim 4, wherein, the sleeve further comprising: an inner tube arranged in the outer tube and sleeved outside the middle core rod, the distal end of the inner tube abutting against the proximal end of the outer fixing ring; the outer diameter of the inner tube is the same as the outer diameter of the outer fixing ring.

6. The COPD electrode catheter of claim 1, wherein, the middle core rod is a solid structure, and the middle core rod is made of nickel-titanium alloy.

7. The COPD electrode catheter of claim 6, wherein, the middle core rod is a conductor, and the distal end of the braided mesh basket structure and / or the proximal end of the braided mesh basket structure is in conductive connection with the middle core rod, so that pulse ablation energy can be transmitted to the braided mesh basket structure.

8. The COPD electrode catheter of claim 6, wherein, the middle core rod is a conductor, and at least one of the protruding ring and the inner fixing ring is a conductor.

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