Body fluid analyzer

By designing a small-volume portable body fluid analyzer, the problems of large size and low detection efficiency of traditional microscopes are solved, home inspection and privacy protection are achieved, and it is suitable for rapid analysis of a variety of body fluids.

CN115704776BActive Publication Date: 2025-08-05CHANGCHUN INST OF OPTICS FINE MECHANICS & PHYSICS CHINESE ACAD OF SCI +1
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Patent Information

Application Number
CN202110943008.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-08-17
Publication Date
2025-08-05
Estimated Expiration
2041-08-17

AI Technical Summary

Technical Problem

The existing medical microscopes are large in size, fixed platform, and require professional personnel to operate, so they cannot achieve home testing and cannot protect privacy cases. The detection efficiency of cases is inefficient.

Method used

A small-volume, compact portable bodily fluid analyzer is designed, including a microscope imaging system, imaging camera, lighting device and display. It adopts contactless or contact observation and supports home inspection, including zoom and zoom functions of the microscope imaging system, combined with CCD or CMOS cameras and mobile phone or flat panel displays.

Benefits of technology

It realizes portable and simple home testing, improves detection efficiency and privacy, and is suitable for rapid analysis of body fluids such as semen, saliva, blood, etc.

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Abstract

The present invention provides a body fluid analyzer, which includes a microscope imaging system, an imaging camera, a lighting device, a liquid carrier device and a display; wherein, the lighting device is arranged in the liquid carrier device and is used for illuminating the body fluid contained in the liquid carrier device; the liquid carrier device and the imaging camera are respectively fixedly connected to the microscope imaging system, and the microscope imaging system is used for magnifying and imaging the body fluid contained in the liquid carrier device on the target surface of the imaging camera; the display is connected to the imaging camera in a wired or wireless manner and is used for displaying the image formed by the imaging camera. Compared with traditional medical microscopes, the present invention is small in size, compact in structure, simple to operate, portable and easy to carry, can achieve home detection, is not restricted by time and place, and can improve privacy and detection efficiency.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical detection, and particularly to a portable multi-functional body fluid analyzer. Background Art

[0002] With the rapid growth of the economy and the rapid increase in population, accompanied by the rapid deterioration of the environment and climate, the deterioration of the climate and environment will have a certain impact on human health. At present, many medical diagnoses of human health are based on body fluid detection, such as saliva, blood, semen, urine, etc., and the detected components include bacteria, viruses, sperm quality, etc. The detection of many targets is based on microscopic observation. Most medical microscopes are large in volume, have fixed platforms, are few in number, and their operation requires professional personnel. Patients need to queue up to wait for the results, with low efficiency, and for some private cases, such as semen detection, privacy cannot be protected. Based on the current situation, there is an urgent need for a portable body fluid analyzer that can be used for home detection. Summary of the Invention

[0003] The purpose of the present invention is to overcome the defects of the prior art and propose a body fluid analyzer with a small volume, large redundancy tolerance, long stroke, and constant force output.

[0004] To achieve the above purpose, the present invention adopts the following specific technical solutions:

[0005] The body fluid analyzer provided by the present invention includes a microscope imaging system, an imaging camera, an illumination device, a liquid loading device, and a display; wherein, the illumination device is arranged in the liquid loading device and is used for illuminating the body fluid contained in the liquid loading device; the liquid loading device and the imaging camera are respectively fixedly connected to the microscope imaging system, and the microscope imaging system is used for magnifying and imaging the body fluid contained in the liquid loading device on the target surface of the imaging camera; the display is connected to the imaging camera in a wired or wireless manner and is used for displaying the image formed by the imaging camera.

[0006] Preferably, the microscope imaging system includes a front fixed lens group, a rear fixed lens group, and a relay lens group. The relay lens group is located between the front fixed lens group and the rear fixed lens group. The front fixed lens group is fixedly connected to the liquid loading device, and the rear fixed lens group is fixedly connected to the imaging camera.

[0007] Preferably, the microscope imaging system further includes a focusing lens group. The focusing lens group is located between the relay lens group and the front fixed lens group, and the zoom of the microscope imaging system is achieved by moving the focusing lens group.

[0008] Preferably, the microscope imaging system further includes a variable magnification lens group. The variable magnification lens group is located between the relay lens group and the rear fixed lens group, and the magnification ratio of the microscope imaging system is changed by moving the variable magnification lens group.

[0009] Preferably, the liquid carrier device includes a mounting housing, a liquid holding pool, and a body fluid overflow channel; wherein, the liquid holding pool is used to hold the body fluid, and the front fixed lens group extends into the liquid holding pool; the body fluid overflow channel is located on the outer circumference of the liquid holding pool and is connected to the liquid holding pool, and is used to collect the body fluid overflowing from the liquid holding pool; the mounting housing includes a bottom plate and a side enclosure plate, the bottom plate and the side enclosure plate enclose a cavity for accommodating the liquid holding pool and the body fluid overflow channel, the side wall of the body fluid overflow channel overlaps with the side enclosure plate, and the front fixed lens group is threadedly connected to the side enclosure plate.

[0010] Preferably, the lighting device includes at least one light source fixed on the bottom plate.

[0011] Preferably, the lighting device includes a light source and a reflector with the same number and at least one. The light sources are distributed around the front fixed lens group and are located obliquely above the liquid holding pool. The reflector is installed and fixed between the bottom plate and the side enclosure plate and is used to reflect the light emitted by the light source to the liquid holding pool.

[0012] Preferably, a light shielding plate is installed at the bottom of the liquid holding pool.

[0013] Preferably, the imaging camera is a CCD camera or a CMOS camera.

[0014] Preferably, the display is a mobile phone, a monitor or a tablet computer.

[0015] Compared with the traditional medical microscope, the present invention is small in volume, compact in structure, simple to operate, portable and easy to carry. It can realize home detection, is not restricted by time and place, and can improve privacy and detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is a schematic diagram of the overall structure of the body fluid analyzer provided by an embodiment of the present invention;

[0017] Figure 2 is a schematic diagram of the structure of the lighting device and the liquid carrier device provided by an embodiment of the present invention.

[0018] The reference numerals therein include: microscope imaging system 1, front fixed lens group 101, rear fixed lens group 102, relay lens group 103, focusing lens group 104, zoom lens group 105, lens barrel 106, imaging camera 2, lighting device 3, light source 301, reflector 302, light shielding plate 303, liquid carrier device 4, mounting housing 401, liquid holding pool 402, body fluid overflow channel 403, bottom plate 404, side enclosure plate 405, and display 5. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] In the following, embodiments of the present invention will be described with reference to the accompanying drawings. In the following description, the same modules are denoted by the same reference numerals. In the case of the same reference numerals, their names and functions are also the same. Therefore, their detailed descriptions will not be repeated.

[0020] In order to make the objectives, technical solutions and advantages of the present invention clearer and more understandable, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and do not constitute a limitation to the present invention.

[0021] Figure 1 The overall structure of a body fluid analyzer provided according to an embodiment of the present invention is shown.

[0022] As Figure 1 shown, the body fluid analyzer provided by the embodiment of the present invention includes: a microscope imaging system 1, an imaging camera 2, a lighting device 3, a liquid carrier device 4, and a display 5. The liquid carrier device 4 is used to carry body fluids (including semen, saliva, blood, urine, etc.). The microscope imaging system 1 is used to image the body fluid carried by the liquid carrier device 4. The imaging camera 2 is used to convert the image formed by the microscope imaging system 1 into a digital signal. The display 5 is used to display the image of the body fluid.

[0023] The microscope imaging system 1 includes a front fixed lens group 101, a rear fixed lens group 102, and a relay lens group 103. The relay lens group 103 is located between the front fixed lens group 101 and the rear fixed lens group 102. The front fixed lens group 101 is fixedly connected to the liquid carrier device 4. The rear fixed lens group 102 is fixedly connected to the imaging camera 2. The positions of the front fixed lens group 101, the rear fixed lens group 102, and the relay lens group 103 are fixed and immovable.

[0024] In an example of the present invention, the microscope imaging system 1 further includes a focusing lens group 104. The focusing lens group 104 is located between the relay lens group 103 and the front fixed lens group 101. The position of the focusing lens group 104 is adjustable. By moving the focusing lens group 104, zooming of the microscope imaging system 1 is achieved to adjust the clarity of the image. Of course, focusing can also be performed by moving the imaging camera 2.

[0025] In another example of the present invention, the microscope imaging system 1 further includes a zoom lens group 105. The zoom lens group 105 is located between the rear fixed lens group 102 and the relay lens group 103. The zoom lens group 105 is an optical zoom structure. By moving the zoom lens group 105, more than two magnification ratios of the microscope imaging system 1 can be achieved. Compared with traditional medical microscopes, the system structure is simplified, and there is no need to switch different magnification lenses to meet different usage requirements.

[0026] The microscope imaging system 1 further includes a lens barrel 106. The front fixed lens group 101, the rear fixed lens group 102, the relay lens group 103, the focusing lens group 104, and the zoom lens group 105 are all installed inside the lens barrel 106, and the focusing lens group 104 and the zoom lens group 105 also slide along the lens barrel 106. Threaded holes are provided on the lens barrel 106. After the positions of the focusing lens group 104 and the zoom lens group 105 are completed, a set screw is screwed into the threaded hole to tighten the focusing lens group 104 and the zoom lens group 105, realizing the fixation of the focusing lens group 104 and the zoom lens group 105. Of course, the fixation of the focusing lens group 104 and the zoom lens group 105 can also be achieved by means of mechanical buckles.

[0027] The imaging camera 2 can be a small-sized, high-resolution CCD camera or CMOS camera. The CCD camera or CMOS camera can be fixedly connected to the rear fixed lens group 102 by threads or by a flange. The microscope imaging system 1 forms an image on the target surface of the CCD camera or CMOS camera.

[0028] The display 5 is a display device such as a mobile phone, a monitor, or a tablet computer for displaying the imaging result. The driving software of the imaging camera 2 and the body fluid analysis software are installed on the display 5.

[0029] The lighting device 3 and the display 5 are respectively in communication with the imaging camera 2 through a wired connection method or a wireless connection method. When the display 5 is wired to the imaging camera 2, it can be connected through a USB cable, and the display 5 supplies power to the imaging camera 2 and the lighting device 3. When the display 5 is wirelessly connected to the imaging camera 2, a battery can be installed in the display 5 or the imaging camera 2 and the lighting device 3 can be powered by inductive charging.

[0030] Figure 2 The structure of the lighting device and the liquid-carrying device according to an embodiment of the present invention is shown.

[0031] As Figure 2 shown, the liquid-carrying device 4 includes an installation housing 401, a liquid storage pool 402, and a body fluid overflow channel 403. The installation housing 401 includes a bottom plate 404 and a side enclosure 405. The bottom plate 404 and the side enclosure 405 enclose a cavity, which is used to accommodate the liquid storage pool 402 and the body fluid overflow channel 403.

[0032] The liquid storage pool 402 is of a cylindrical structure for storing body fluid. The diameter of the liquid storage pool 402 is slightly larger than the diameter of the front fixed lens group 101, so that the front end of the front fixed lens group 101 can extend into the liquid storage pool 402.

[0033] The body fluid overflow channel 403 is located on the outer circumference of the liquid storage pool 402, is arranged around the liquid storage pool 402 in a circle and is connected to the liquid storage pool 402, and is used to collect the body fluid overflowing from the liquid storage pool 402. The outer wall of the body fluid overflow channel 403 horizontally extends with an outer edge, there is a step on the side enclosure plate 405, and the outer edge extended by the body fluid overflow channel 403 is lapped on the step of the side enclosure plate 405 and is fixed by means such as glue. There is also an internal thread provided on the inner wall of the side enclosure plate 405, and an external thread is provided on the edge of the front fixed lens group 101, and the front fixed lens group 101 is threadedly connected to the side enclosure plate 405 to achieve the fixation of the two.

[0034] The way the microscope imaging system 1 observes the body fluid is non-contact or contact. Non-contact means that the front end of the front fixed lens group 101 does not contact the body fluid in the liquid storage pool 402, and contact means that the front end of the front fixed lens group 101 contacts the body fluid in the liquid storage pool 402.

[0035] When the front end of the front fixed lens group 101 does not contact the body fluid in the liquid storage pool 402, the body fluid will not be squeezed into the body fluid overflow channel 403. When the front end of the front fixed lens group 101 contacts the body fluid in the liquid storage pool 402, the front end of the front fixed lens group 101 squeezes the body fluid, causing the body fluid to overflow and flow into the body fluid overflow channel 403, and the body fluid overflow channel 403 can prevent the excess body fluid from contaminating other structures.

[0036] The illumination method of the illumination device 3 is divided into two types according to the different positions of the light source, namely direct illumination and reflective illumination. Direct illumination is to install at least one light source 301 on the bottom plate 404 to directly illuminate the body fluid in the liquid storage pool 402. Reflective illumination is to evenly distribute the light sources 301 around the front fixed lens group 101. The light sources 301 are located at the obliquely upper position of the liquid storage pool 402, and a reflector 302 is provided corresponding to each light source 301. Multiple reflectors 302 are respectively installed obliquely between the bottom plate 404 and the side enclosure plate 405 to reflect the light emitted by the light sources 301 to the liquid storage pool 402 to illuminate the body fluid in the liquid storage pool 402.

[0037] Both direct illumination and reflective illumination belong to the bright field illumination method. The embodiment of the present invention can also adopt the dark field illumination method, and a light shielding plate 303 is installed at the bottom of the liquid storage pool 402 to cover most of the area at the bottom of the liquid storage pool 402, so that the light emitted by the light source 301 can only enter the liquid storage pool 402 from the gap.

[0038] The body fluid analyzer provided by the embodiment of the present invention can detect and analyze body fluids such as semen, saliva, blood, urine, etc. The use process of the body fluid analyzer is as follows:

[0039] Open the driver software of the imaging camera 2 on the display 5, adjust the focusing lens group 104 in the microscope imaging system 1 to make the body fluid clearly imaged, and observe the imaging result of the body fluid in real time. Adjust the zoom lens group 105 to achieve magnification of different magnifications of the body fluid to meet different observation requirements; there is a standard body fluid image built in the body fluid analysis software. By comparing the body fluid image displayed on the display 5 with the built-in body fluid image, judge whether the body fluid index is qualified. If not, go to the hospital for treatment as soon as possible to prevent delaying the condition.

[0040] In the description of this specification, the description referring to terms such as "one embodiment", "some embodiments", "one example", "another example" or "specific example" etc. means that the specific features, structures, materials or characteristics described in connection with that embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in a suitable manner in any one or more embodiments or examples. In addition, without contradiction, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0041] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those of ordinary skill in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

[0042] The above specific embodiments of the present invention do not constitute a limitation on the protection scope of the present invention. Any other corresponding changes and deformations made according to the technical concept of the present invention should be included in the protection scope of the claims of the present invention.

Claims

1. A body fluid analyzer, characterized in that: It includes a microscope imaging system, an imaging camera, a lighting device, a liquid carrying device and a display; wherein, The lighting device is disposed in the liquid carrying device and is used to illuminate the body fluid contained in the liquid carrying device; The microscope imaging system includes a front fixed mirror group, a rear fixed mirror group and a relay mirror group, wherein the relay mirror group is located between the front fixed mirror group and the rear fixed mirror group, the front fixed mirror group is fixedly connected to the liquid carrying device, and the rear fixed mirror group is fixedly connected to the imaging camera; The liquid carrying device and the imaging camera are respectively fixedly connected to the microscope imaging system, and the microscope imaging system is used to magnify the body fluid contained in the liquid carrying device and image it on the target surface of the imaging camera; the liquid carrying device includes a mounting shell, a liquid storage tank and a body fluid overflow channel; wherein, the liquid storage tank is used to hold the carrier liquid, and the front fixed mirror group extends into the liquid storage tank; the body fluid overflow channel is located on the outer circumference of the liquid storage tank and is connected to the liquid storage tank, and is used to collect the body fluid overflowing from the liquid storage tank; the mounting shell includes a bottom plate and a side panel, the bottom plate and the side panel form a cavity for accommodating the liquid storage tank and the body fluid overflow channel, the side wall of the body fluid overflow channel overlaps the side panel, and the front fixed mirror group is threadedly connected to the side panel; The display is connected to the imaging camera via a wired or wireless connection and is used to display the image formed by the imaging camera.

2. The body fluid analyzer according to claim 1, wherein The microscope imaging system further comprises a focusing lens group, which is located between the relay lens group and the front fixed lens group. The microscope imaging system is zoomed by moving the focusing lens group.

3. The body fluid analyzer according to claim 2, wherein: The microscope imaging system further includes a magnification lens group, which is located between the relay lens group and the rear fixed lens group. The magnification of the microscope imaging system can be changed by moving the magnification lens group.

4. The body fluid analyzer according to claim 1, wherein The lighting device includes at least one light source fixed on the base plate.

5. The body fluid analyzer according to claim 1, wherein The lighting device includes an equal number of at least one light source and a reflector. The light sources are distributed around the front fixed mirror group and are located obliquely above the liquid storage tank. The reflector is installed and fixed between the bottom plate and the side panel to reflect the light emitted by the light source to the liquid storage tank.

6. The body fluid analyzer according to claim 4 or 5, characterized in that: A light shielding plate is installed at the bottom of the liquid storage tank.

7. The body fluid analyzer according to claim 1, wherein The imaging camera is a CCD camera or a CMOS camera.

8. The body fluid analyzer according to claim 1, wherein The display is a mobile phone, a monitor or a tablet computer.

Citation Information

Patent Citations

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