Automatic quantitative liquid injection method for blood culture bottle

Through the automatic quantitative injection method of blood culture bottles, special devices are used to realize automatic quantitative injection of blood culture bottles, which solves the problems of low manual injection efficiency and poor accuracy, and improves operational safety and work efficiency.

CN115902281BActive Publication Date: 2025-08-12AUTOBIO LABTEC INSTR CO LTD
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Patent Information

Application Number
CN202211443532.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-11-18
Publication Date
2025-08-12
Estimated Expiration
2042-11-18

AI Technical Summary

Technical Problem

In the prior art, the reagent injection method of blood culture bottles has the risk of improper operation leading to injury to the operator, and the manual injection efficiency is low and the accuracy is poor, which cannot meet the demand for rapid quantification.

Method used

The automatic quantitative injection method of blood culture bottle is adopted, and a special quantitative injection device of blood culture bottle is used, including a quantitative injection system, lifting mechanism, culture bottle support mechanism and electronic control system. Automatic quantitative injection is achieved through injection pumps, rotating tables and sensors, avoiding manual insertion and removal of injection needles, and improving injection efficiency and accuracy.

Benefits of technology

The continuous automatic quantitative injection of multiple blood culture bottles is achieved, which improves the injection efficiency and accuracy, reduces the operational risk, and ensures the accuracy and efficiency of blood culture results.

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Abstract

The present invention discloses a method for automatic quantitative injection of blood culture bottles, comprising the following steps: first, placing the blood culture bottle on a rotating table, a first power source driving the injection needle to descend to a preset height and insert it into the blood culture bottle below, the injection pump starting and injecting reagent into the blood culture bottle; second, the first power source driving the clamping unit to rise and reset; third, the second power source driving the rotating table to rotate the next blood culture bottle to the bottom of the injection needle, and performing quantitative injection operation; fourth, repeating the first to third steps to complete the continuous automatic quantitative operation of multiple blood culture bottles. The present invention utilizes the injection pump to automatically and quantitatively inject reagents into the blood culture bottle, thereby improving injection efficiency and injection accuracy; the first power source can realize the insertion and removal of the injection needle without manual insertion and removal, thereby improving operational safety; the second power source drives the blood culture bottle to rotate, thereby realizing continuous quantitative injection of multiple blood culture bottles, thereby improving work efficiency.
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Description

Technical Field

[0001] The invention relates to the field of blood culture, in particular to an automatic quantitative liquid injection method for a blood culture bottle. Background Art

[0002] Blood cultures are widely used to detect persistent high fevers in children and postoperative infections. They are typically performed in blood culture bottles. A blood sample is placed in the bottle, followed by the reagents necessary for bacterial growth. The entire process must be sterile and airtight. Any air or contaminants present will render the blood culture useless. Therefore, during the blood culture process, the injection process must be sterile and airtight. Furthermore, the amount of reagent injected is a key indicator of blood culture results. Excessive reagent in the bottle increases the number of bacteria involved in the culture, meaning more bacteria can be cultured within the specified reaction time, leading to a false-positive report. Excessive reagent in the bottle reduces the number of bacteria cultured within the specified reaction time, resulting in a false-negative report. Therefore, before blood culture bottles are shipped, a quantitative injection of culture reagent is often performed to verify their functionality. During subsequent blood culture procedures, this quantitative injection of reagent is also necessary to achieve optimal results.

[0003] Currently, manual injection is the most common method for injecting culture reagents during blood culture. This involves manually injecting the reagent into the blood culture bottle using a syringe, and visually determining the injection volume based on the scale lines on the syringe. However, improper manual injection with a syringe can result in operator injury and even contamination of the operator's wound with the reagent. Furthermore, manual injection is inefficient and cannot meet the rapid quantitative requirements for large numbers of blood culture bottles. Furthermore, visually determining the injection volume during the injection process can lead to significant errors and low accuracy, which in turn affects the determination of the culture reagent volume in the blood culture bottle. Summary of the Invention

[0004] In view of this, the present invention provides an automatic quantitative injection method for blood culture bottles, which realizes the continuous injection of multiple blood culture bottles with high injection efficiency and high injection accuracy. It not only helps manufacturers to quickly determine the reagent injection volume of blood culture bottles, but is also suitable for blood culture in blood culture testing institutions.

[0005] To achieve the above object, the present invention adopts the following technical solutions:

[0006] The blood culture bottle automatic quantitative injection method of the present invention adopts a special blood culture bottle quantitative injection device, which includes a base;

[0007] The mounting frame comprises a first mounting unit arranged vertically and a second mounting unit and a third mounting unit arranged horizontally, wherein the second mounting unit and the third mounting unit are arranged on the first mounting unit at intervals;

[0008] A quantitative injection system comprising a liquid storage container, an injection pump, and an injection needle connected in sequence via an injection pipeline, wherein the injection pump is arranged on the second mounting unit, and the liquid storage container is arranged on the third mounting unit;

[0009] a lifting mechanism, disposed on the first mounting unit, comprising a first power source and a clamping unit for fixing the injection needle, wherein the clamping unit is in transmission connection with the first power source; and

[0010] a culture bottle supporting mechanism, disposed on the base, comprising a second power source and a rotating table driven by the second power source for supporting the culture bottle;

[0011] The detection unit comprises a first sensor provided on the mounting frame and a second sensor for recording the number of injections by the injection needle, and a trigger piece cooperating with the first sensor is provided on the lifting member of the lifting mechanism;

[0012] An electronic control system comprising a control unit, wherein a signal input terminal of the control unit is connected to the signal output terminals of the first sensor and the second sensor respectively, and a control output terminal of the control unit is connected to the control input terminals of the first power source and the second power source respectively;

[0013] The method for automatically quantitatively filling a blood culture bottle comprises the following steps:

[0014] In the first step, a blood culture bottle is placed on a rotating table. The control unit sends an injection command to the first power source. The first power source receives the command from the control unit and drives the injection needle to descend to a preset height and insert it into the blood culture bottle below. After the injection needle is in place, the control unit controls the injection pump to start and inject reagent into the blood culture bottle.

[0015] In the second step, after the injection is completed, the control unit controls the injection pump to stop working, and sends a rotation instruction to the second power source and a reset instruction to the first power source respectively. The first power source drives the clamping unit to rise and reset. The first sensor detects the signal of the trigger piece and transmits it to the control unit. The control unit generates an instruction for the clamping unit to reach the original position based on the information obtained and controls the lifting mechanism to stop working.

[0016] In the third step, the second power source receives the rotation command from the control unit and drives the rotating table to rotate by a preset angle, so that the next blood culture bottle is rotated to the position directly below the injection needle. The first and second steps are repeated to complete the automatic quantitative injection operation of the second blood culture bottle.

[0017] Step 4: Repeat steps 1 to 3 to complete the continuous automatic quantitative operation of multiple blood culture bottles;

[0018] During the reciprocating process of the clamping unit, the second sensor obtains the reciprocating signal of the clamping unit and transmits it to the control unit. The control unit generates the number of reciprocating times and the number of injections based on the received reciprocating signal of the clamping unit. When the number of injections exceeds the preset value, the control unit generates an alarm signal and sends it to the alarm unit, and the alarm unit sounds an alarm.

[0019] In the above scheme, the present invention utilizes an infusion pump to automatically and quantitatively inject reagents into a blood culture bottle, thereby improving both the efficiency and accuracy of the infusion. In addition, during the infusion process, the lifting mechanism can drive the infusion needle up and down, thereby enabling the insertion and removal of the infusion needle without manual insertion and removal, thereby improving operational safety. Furthermore, during the infusion, the present invention uses a second power source to drive the blood culture bottle to rotate, making it convenient for the operator to promptly remove the blood culture bottle after quantitative infusion and place another blood culture bottle to be infused, thereby achieving continuous quantitative infusion of multiple blood culture bottles and improving work efficiency.

[0020] The present invention records the number of injections of the injection needle through the second sensor and the control unit. When the number of injections exceeds a preset value, the control unit generates an alarm signal, which causes the alarm of the control unit to sound, reminding the operator to replace the injection needle in time, thereby ensuring normal injection.

[0021] Preferably, the base is an electronically controlled base, the control unit is disposed within the electronically controlled base, and the alarm unit (which may be a buzzer, a display light, or a combination of a buzzer and a display light) is disposed on the electronically controlled base. More preferably, the electronically controlled base is further provided with a control panel having a display screen and an emergency stop switch. During operation, the injection volume can be set via the control panel; in the event of an emergency, the injection operation can be abruptly stopped using the emergency stop switch.

[0022] In a preferred embodiment of the present invention, the infusion pump is a peristaltic pump, and a control input of the infusion pump is connected to a control output of the control unit. During operation, the control unit automatically controls the activation and deactivation of the infusion pump, thereby achieving automatic quantitative infusion of each blood culture bottle and improving the accuracy of infusion.

[0023] In another preferred embodiment of the present invention, the injection pump has a foot switch for controlling the opening and closing of the injection pump. During operation, the present invention can also utilize the foot switch to control the opening and closing of the injection pump.

[0024] Preferably, the first power source is a screw stepper motor, or a first motor and a transmission screw driven by the first motor, or a screw driven by a synchronous belt transmission mechanism, or an electric push rod, or a linear motor; the second power source is a second motor, or a motor reducer with a reduction ratio, or a gear transmission mechanism, or a chain transmission mechanism, or a belt transmission mechanism. During actual installation, the present invention can determine the first power source and the second power source according to actual conditions (such as installation space, cost, etc.). More preferably, the first power source is a linear motor, and the lifting member is a sliding block of the linear motor. In the present invention, the first power source is preferably a linear motor with a guide rail to ensure the linear motion trajectory and motion accuracy of the clamping unit. In addition, in the present invention, the second power source is preferably a second motor.

[0025] Preferably, the first mounting unit is a vertical beam, the second mounting unit is a first horizontal beam horizontally mounted on the vertical beam, and the third mounting unit is a second horizontal beam horizontally mounted on the vertical beam. The second horizontal beam is located above the first horizontal beam, ensuring that the liquid storage container is located above the injection pump.

[0026] In a preferred embodiment of the present invention, the peristaltic pump is provided with a silicone hose with a connecting joint, and the injection pipeline is an injection hose, which connects the liquid storage container, the silicone hose and the injection needle together. More preferably, the injection hose is a disposable infusion set with a Luer connector. That is, the present invention uses a disposable sterile infusion set with a Luer connector to connect the liquid storage container, the peristaltic pump and the injection needle together. It is cheap, easy to obtain and sterile, simple and convenient to replace, easy to operate and reduces the cost of automatic injection of blood culture bottles; in addition, the combination of the Luer connector and the injection pipeline effectively guarantees the air tightness, water tightness and a certain negative pressure during the injection process, ensuring negative pressure injection and avoiding the entry of gas into the culture bottle. Furthermore, accessories such as an infusion heater and an infusion pump can also be installed on the injection hose.

[0027] Compared with the existing technology, the present invention only requires the operator to place the culture bottle on the rotating table or remove the blood culture bottle on the rotating table, and does not require manual insertion and removal of the injection needle. It can also ensure the quantitative injection of each blood culture bottle, realize continuous injection, and improve the injection efficiency. Specifically:

[0028] The present invention utilizes a lifting mechanism to drive the injection needle to rise and fall, thereby realizing the insertion and removal of the injection needle without manual insertion and removal, thereby improving operational safety. In addition, during injection, an injection pump is used to automatically and quantitatively inject reagents into the blood culture bottle, which not only improves the injection efficiency but also improves the injection accuracy.

[0029] During the injection process, the present invention drives the blood culture bottle to rotate through the second power source, which makes it convenient for the operator to promptly remove the blood culture bottle after quantitative injection and place another blood culture bottle to be injected, thereby realizing continuous quantitative injection of multiple blood culture bottles and improving work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a structural schematic diagram of the present invention.

[0031] Figure 2 It is a piping diagram of the quantitative injection system of the present invention.

[0032] Figure 3 It is a circuit principle block diagram of the present invention.

[0033] Figure 4 It is a schematic diagram of the connection between the injection needle and the clamping unit of the present invention.

[0034] Figure 5 yes Figure 4 AA direction schematic diagram. DETAILED DESCRIPTION

[0035] The following describes an embodiment of the present invention in detail with reference to the accompanying drawings. This embodiment is implemented based on the technical solution of the present invention, and provides a detailed implementation method and specific operation process. However, the protection scope of the present invention is not limited to the following embodiment.

[0036] It should be noted that in the description of the following embodiments, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed connections, detachable connections, or integral connections; mechanical connections or electrical connections; direct connections or indirect connections through an intermediate medium; and internal connections between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0037] In addition, it should be noted that in the description of the following embodiments, the terms "front", "rear", "left", "right", "vertical", "horizontal", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they cannot be understood as limiting the present invention.

[0038] The present invention provides an automatic quantitative liquid filling method for a blood culture bottle, which realizes automatic filling of culture fluid in each blood culture bottle, improves the liquid filling accuracy and liquid filling efficiency, and frees hands.

[0039] Specifically, the method for automatically injecting liquid into a blood culture bottle according to the present invention adopts a dedicated device for injecting liquid into a blood culture bottle. Figure 1-2 It can be seen that the blood culture bottle quantitative injection device includes a base 1, a mounting frame, a quantitative injection system, a lifting mechanism, a culture bottle supporting mechanism, an electronic control system and a detection component;

[0040] The mounting frame is located on one side of the base 1 and comprises a first mounting unit (i.e., vertical beam 2.1), a second mounting unit (i.e., first crossbeam 2.2), and a third mounting unit (i.e., second crossbeam 2.3) mounted horizontally on top of the vertical beam 2.1. The second crossbeam 2.3 is located above the first crossbeam 2.2. During actual installation, the vertical beam 2.1 is preferably fixed to the base 1 so that the entire unit can be moved by simply moving the base 1, making it easy to relocate.

[0041] The quantitative injection system includes a liquid storage container 3.1, an injection pump 3.2 (preferably a peristaltic pump), and an injection needle 3.3 (a commercially available infusion needle or injection needle) connected in sequence via an injection pipeline. The injection pump 3.2 is mounted on the first crossbeam 2.2, and the liquid storage container 3.1 is mounted on the second crossbeam 2.3.

[0042] The lifting mechanism comprises a first power source disposed on a first mounting unit, a sliding member, and a clamping unit (i.e., clamping unit 4) for securing the injection needle 3.3. The clamping unit 4 is connected to the first power source via the sliding member. The up and down movement of the lifting mechanism enables the injection needle 3.3 to be automatically inserted and removed from the blood culture bottle stopper.

[0043] The culture bottle support mechanism is mounted on the base 1 and includes a second power source 5.3 and a rotating platform 5.1 driven by the second power source 5.3 to support the culture bottle. Each time a blood culture bottle is injected, the second power source 5.3 rotates the rotating platform 5.1 by a preset angle, allowing another blood culture bottle to be injected to be positioned directly below the injection needle 3.3. This allows for continuous injection of the blood culture bottles, improving work efficiency.

[0044] The detection assembly includes a first sensor 7.1 (preferably a groove-type photoelectric switch, installed at the initial height) and a second sensor 7.3, mounted on one side of the vertical beam 2.1. A trigger plate 7.2 is mounted on the slider, which engages the groove of the first sensor 7.1. When the trigger plate 7.2 rises with the slider 6.2 and triggers the first sensor 7.1, it indicates that the slider 6.2 and the clamping unit 4 have reached their initial height. The second sensor 7.3 (preferably an infrared sensor) is mounted on the first horizontal beam 2.2 near the vertical beam 2.1. During the automatic injection process, the second sensor 7.3 detects the number of round trips of the slider or lifting unit to determine the number of injections made by the injection needle 3.3.

[0045] The electronic control system includes a control unit (i.e., a single-chip microcomputer) disposed within a base and an alarm unit (i.e., an alarm, preferably a buzzer) disposed on the base (i.e., the electronic control base). The signal input end of the single-chip microcomputer is connected to the signal output ends of the first sensor 7.1 and the second sensor 7.3, respectively. The control output end of the single-chip microcomputer is connected to the control input ends of the linear motor 6.1, the second power source 5.3, and the peristaltic pump, respectively. The signal output end of the single-chip microcomputer is connected to the signal input end of the alarm. The first sensor 7.1 and the second sensor 7.3 transmit detected information to the controller, which determines the maximum rise position of the slider 6.2, the number of injections, and the rotation of the rotary table 5.1, thereby achieving quantitative injection of each blood culture bottle on the rotary table 5.1, improving the automated continuous injection of multiple blood culture bottles and improving injection efficiency.

[0046] In actual installation, combined with Figure 2 As can be seen, the infusion line is a disposable output device, comprising a first hose 3.4 connected to the liquid storage container 3.1 and a second hose 3.5 connected to the infusion needle 3.3 (a commercially available infusion needle or syringe needle can be used). Both the first hose 3.4 and the second hose 3.5 are connected to the peristaltic pump hose 3.6 (typically silicone tubing) of the peristaltic pump via a pair of Luer connectors. In other words, the present invention utilizes a disposable sterile infusion set with a Luer connector to connect the liquid storage container, peristaltic pump, and infusion needle. This is inexpensive, readily available (costing less than two yuan), sterile, and easy to replace, simplifying operation and reducing the cost of automated infusion of blood culture bottles. Furthermore, the combination of the Luer connector and the infusion line effectively ensures airtightness, watertightness, and a certain negative pressure during the infusion process, ensuring negative pressure infusion and preventing gas from entering the culture bottle. Furthermore, the infusion hose can be equipped with accessories such as an infusion heater and infusion aid.

[0047] Combine Figure 1 It can be seen that the first power source of the lifting mechanism is preferably a linear motor 6.1 with a guide rail. The linear motor 6.1 has a lifting part (i.e., a sliding block 6.2) that slides up and down along the guide rail. The clamping unit (i.e., the clamping unit 4) is fixed on the sliding block 6.2. The linear motor 6.1 drives the clamping unit 4 to move back and forth up and down through the sliding block 6.2, which can not only realize the up and down reciprocating lifting and lowering of the injection needle 3.3, but also ensure the movement accuracy of the injection needle 3.3, thereby meeting the plugging and unplugging requirements during quantitative injection of blood culture bottles.

[0048] During actual installation, the linear motor 6.1 in this embodiment can be replaced by other power sources that can realize linear lifting and lowering of the clamping unit 4, such as a screw stepper motor, a motor and a screw connected to the motor, a screw driven by a synchronous belt transmission mechanism, a cylinder, a hydraulic cylinder and an electric push rod, etc.

[0049] The method for automatically quantitatively filling a blood culture bottle according to the present invention comprises the following steps:

[0050] The first step is to hang the liquid storage container 3.1 on the second crossbeam 2.3, fix the peristaltic pump body on the first crossbeam 2.2, insert the inlet end of the first hose 3.4 into the liquid storage container 3.1, then respectively insert the first hose 3.4 and the second hose 3.5 into the peristaltic pump hose 3.6, and finally clamp the injection needle 3.3 onto the clamping unit 4 to complete the installation of the quantitative injection system;

[0051] Step 2: Set the injection flow rate and injection time of the blood culture bottles according to their specifications. Place four blood culture bottles (of course, five or six bottles are also possible) evenly spaced in a circular direction on the rotating table 5.1.

[0052] The single-chip microcomputer sends an injection command to the linear motor 6.1, which drives the sliding block 6.2 downward, thereby driving the clamping unit 4 and the injection needle 3.3 downward. The lower part of the injection needle 3.3 passes through the soft stopper of the blood culture bottle. The single-chip microcomputer sends an injection command to the peristaltic pump, which uses the peristaltic pump to accurately inject the blood culture bottle.

[0053] In the third step, after the injection is completed, the microcontroller controls the peristaltic pump to stop and sends a reset command to the linear motor 6.1. The slider 6.2 of the linear motor 6.1 rises and resets. The injection needle 3.3 is pulled out of the blood culture bottle and rises synchronously with the slider 6.2. When the trigger piece 7.2 on the slider 6.2 moves into the first sensor 7.1, the microcontroller controls the linear motor 6.1 to stop.

[0054] At the same time, the single-chip microcomputer sends a rotation command to the second power source 5.3, which drives the rotating table 5.1 to rotate by a preset angle (if the rotating table has only four culture positions, the second power source rotates 90 degrees each time; similarly, if the rotating table has six culture positions along the circumference, the second power source rotates 60 degrees each time) so that another blood culture bottle is rotated to directly under the injection needle 3.3. The above second step is repeated to complete the injection of the second culture bottle;

[0055] By repeating this process, the automatic continuous quantitative injection of multiple culture bottles can be achieved. The staff only needs to take away the blood culture bottles after the quantitative injection and replenish new blood culture bottles to be injected. There is no need for manual injection. The degree of automation is high, and the continuous injection of batches of blood culture bottles can be achieved, thereby improving work efficiency.

[0056] During the injection process, since the injection needle 3.3 is a consumable and will be damaged after repeated use, the single-chip microcomputer records the number of round trips of the clamping unit 4 through the second sensor 7.3 to determine the number of injections of the injection needle 3.3; when the injection needle 3.3 is used more than 20 times (of course it can also be 25 times, 30 times, etc.), the alarm will sound to remind the staff to replace the second hose 3.5 and the injection needle 3.3 to ensure the normal progress of the injection operation.

[0057] During actual installation, the culture bottle supporting mechanism further includes a bracket 5.2 fixed on the base 1, the second power source 5.3 is a motor reducer fixed on the bracket 5.2, and the rotating table 5.1 is fixed on the motor shaft of the motor. The rotating table 5.1 is used to support multiple blood culture bottles F placed along its circumferential direction, thereby realizing the continuous liquid filling operation of the blood culture bottles F, thereby improving the liquid filling efficiency. Figure 1 shown.

[0058] For easy operation, a control panel 7.4 with a display screen is also provided on the electric control base (see Figure 1 ) and an emergency stop switch allow the filling flow rate and time for each blood culture bottle to be set via control panel 7.4, ensuring automatic filling of each blood culture bottle with high accuracy and no manual intervention. In an emergency, the emergency stop switch can be used to stop the filling process immediately to protect the sample and the device.

[0059] Combine Figure 4 and Figure 5 As can be seen, the clamping unit 4 includes a first fixing block 4.1 fixed to the sliding block 6.2 and a second fixing block 4.2 fixed to the first fixing block 4.1 via bolts. A curved retaining ring for retaining the injection needle 3.3 is provided in the gap between the first and second fixing blocks 4.1, 4.2. During use, the upper portion of the injection needle 3.3 can be retained within the curved retaining ring 4.3 to secure the injection needle 3.3.

[0060] In other embodiments of the present invention, the peristaltic pump has a foot switch for controlling the opening and closing of the peristaltic pump. The foot switch controls the opening and closing of the peristaltic pump through the driver of the peristaltic pump to achieve flexible control of the peristaltic pump. Whether to equip the peristaltic pump with a foot switch is selected according to the user's needs at the factory.

[0061] Finally, it should be emphasized that the above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments without inventive effort, or replace some of the technical features therein with equivalents. Therefore, any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A method for automatically injecting liquid into a blood culture bottle, characterized by: A dedicated blood culture bottle quantitative injection device is used, which includes a base; The mounting frame comprises a first mounting unit arranged vertically and a second mounting unit and a third mounting unit arranged horizontally, wherein the second mounting unit and the third mounting unit are arranged on the first mounting unit at intervals; A quantitative injection system comprising a liquid storage container, an injection pump, and an injection needle connected in sequence via an injection pipeline, wherein the injection pump is arranged on the second mounting unit, and the liquid storage container is arranged on the third mounting unit; a lifting mechanism, disposed on the first mounting unit, comprising a first power source and a clamping unit for fixing the injection needle, wherein the clamping unit is in transmission connection with the first power source; as well as a culture bottle supporting mechanism, disposed on the base, comprising a second power source and a rotating table driven by the second power source for supporting the culture bottle; The detection unit comprises a first sensor provided on the mounting frame and a second sensor for recording the number of injections by the injection needle, and a trigger piece cooperating with the first sensor is provided on the lifting member of the lifting mechanism; An electronic control system comprising a control unit and an alarm unit, wherein a signal input terminal of the control unit is connected to the signal output terminals of the first sensor and the second sensor respectively, and a control output terminal of the control unit is connected to the control input terminals of the first power source and the second power source respectively; The method for automatically quantitatively filling a blood culture bottle comprises the following steps: In the first step, a blood culture bottle is placed on a rotating table. The control unit sends an injection command to the first power source. The first power source receives the command from the control unit and drives the injection needle to descend to a preset height and insert it into the blood culture bottle below. After the injection needle is in place, the control unit controls the injection pump to start and inject reagent into the blood culture bottle. In the second step, after the injection is completed, the control unit controls the injection pump to stop working, and sends a rotation instruction to the second power source and a reset instruction to the first power source respectively. The first power source drives the clamping unit to rise and reset. The first sensor detects the signal of the trigger piece and transmits it to the control unit. The control unit generates an instruction for the clamping unit to reach the original position based on the information obtained and controls the lifting mechanism to stop working. In the third step, the second power source receives the rotation command from the control unit and drives the rotating table to rotate by a preset angle, so that the next blood culture bottle is rotated to the position directly below the injection needle. The first and second steps are repeated to complete the automatic quantitative injection operation of the second blood culture bottle. Step 4: Repeat steps 1 to 3 to complete the continuous automatic quantitative operation of multiple blood culture bottles; During the reciprocating process of the clamping unit, the second sensor obtains the reciprocating signal of the clamping unit and transmits it to the control unit. The control unit generates the number of reciprocating times and the number of injections based on the received reciprocating signal of the clamping unit. When the number of injections exceeds the preset value, the control unit generates an alarm signal and sends it to the alarm unit, and the alarm unit sounds an alarm.

2. The method for automatically injecting liquid into a blood culture bottle according to claim 1, wherein: The injection pump is a peristaltic pump, and a control input end of the peristaltic pump is connected to a control output end of the control unit.

3. The method for automatically injecting liquid into a blood culture bottle according to claim 2, characterized in that: The injection pump also has a foot switch for controlling the opening and closing of the injection pump.

4. The method for automatically injecting liquid into a blood culture bottle according to claim 2 or 3, characterized in that: The base is an electric control base, and the control unit is arranged in the electric control base.

5. The method for automatically injecting liquid into a blood culture bottle according to claim 1, wherein: The first power source is a screw stepping motor, or a first motor and a transmission screw driven by the first motor, or a screw driven by a synchronous belt transmission mechanism, or an electric push rod, or a linear motor; The second power source is a second motor, or a motor reducer with a reduction ratio, or a gear transmission mechanism, or a chain transmission mechanism, or a belt transmission mechanism.

6. The method for automatically injecting liquid into a blood culture bottle according to claim 2, characterized in that: The first power source is a linear motor, and the lifting member is a sliding block of the linear motor.

7. The method for automatically injecting liquid into a blood culture bottle according to claim 1, characterized in that: The first installation unit is a vertical beam arranged vertically, the second installation unit is a first horizontal beam arranged horizontally on the vertical beam, and the third installation unit is a second horizontal beam arranged horizontally on the vertical beam.

8. The method for automatically injecting liquid into a blood culture bottle according to claim 2, characterized in that: The peristaltic pump is provided with a silicone hose with a connecting joint, and the injection pipeline is an injection hose, which connects the liquid storage container, the silicone hose and the injection needle together.

9. The method for automatically injecting quantitative liquid into a blood culture bottle according to claim 8, characterized in that: The injection hose and the injection needle are disposable infusion sets with Luer connectors.

Citation Information

Patent Citations

  • Automatic quantitative liquid injection device for blood culture bottle

    CN218561099U