A centrifuge tube cover with homogenization function and a centrifuge tube
By integrating homogenizing components inside centrifuge tubes, closed-loop homogenization is achieved, solving the problems of toxic reagent volatilization and sample transfer, and improving experimental efficiency.
Patent Information
- Application Number
- CN202310091473.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-02-01
- Publication Date
- 2026-01-02
- Estimated Expiration
- 2043-02-01
AI Technical Summary
The existing homogenizers have open homogenization bottles, which cause toxic and harmful reagents to volatilize and harm laboratory personnel. Furthermore, the process of transferring samples to centrifuge tubes for centrifugation after homogenization is cumbersome and inefficient.
Design a centrifuge tube cap with homogenization function, comprising a cap body and a homogenization component, capable of homogenization within a sealed centrifuge tube, including a stator, rotor and drive device, utilizing cutting force and friction to homogenize, and then directly centrifuging the processed product.
Handling toxic reagents under closed conditions avoids volatilization, simplifies experimental procedures, and improves efficiency.
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Figure CN116020583B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of homogenization processing equipment, in particular to a centrifuge tube cover with homogenization function and a centrifuge tube. BACKGROUND
[0002] Before detecting an object, a homogenizer is needed to homogenize a detection sample, and then centrifugal separation is performed. The detection sample includes but is not limited to vegetables, fruits, Chinese herbal medicines, aquatic products and meat products. During homogenization processing, an extraction reagent needs to be added. In the prior art, whether it is a handheld homogenizer, a multi-channel homogenizer or a fully automatic homogenizer, they are all open homogenizers, and the extraction reagent is a volatile toxic reagent, which is very harmful to the environment and experimental personnel. Moreover, after homogenization is completed, the sample in the homogenization bottle needs to be transferred to a centrifuge tube for the next step of centrifugal separation, which reduces the work efficiency. Therefore, there is an urgent need for a new scheme to solve the above problems. SUMMARY
[0003] The present application aims to provide a centrifuge tube cover with homogenization function and a centrifuge tube to solve the problems existing in the prior art. The problems of toxic and harmful reagents harming experimental personnel due to the open homogenization bottle during homogenization and the cumbersome process of transferring the sample in the homogenization bottle to a centrifuge tube for centrifugal separation are solved.
[0004] To achieve the above-mentioned purpose, the present application provides the following scheme:
[0005] The present application provides a centrifuge tube cover with homogenization function, which comprises a cover body and a homogenization assembly. The cover body is used to cover the opening of a centrifuge tube. The homogenization assembly is used to homogenize a detection sample and an extraction reagent in the centrifuge tube.
[0006] Preferably, the cover body is detachably connected to the centrifuge tube.
[0007] Preferably, the homogenization assembly comprises a stator, a rotor and a rotor driving device. The stator and the rotor are both arranged on the inner side of the cover body. The stator is fixedly arranged. The rotor is rotatable. The rotor driving device can drive the rotor to rotate relative to the stator and utilize the cutting force and the friction force between the rotor and the object to homogenize the detection sample.
[0008] Preferably, the homogenization assembly comprises a crushing blade and a blade driving device. The crushing blade is arranged on the inner side of the cover body. The blade driving device can drive the crushing blade to rotate.
[0009] Preferably, in use, the centrifuge tube is inverted.
[0010] Preferably, the centrifuge tube cover is made of PE or PP, the stator is made of PE or stainless steel, and the rotor is made of PC or stainless steel.
[0011] Preferably, a plurality of stators are arranged around the rotor.
[0012] Preferably, the stator is provided with friction teeth on the side facing the rotor.
[0013] Preferably, the rotating shaft of the rotor is supported by a fixed bearing, a dynamic sealing ring is arranged below the rotor to seal the gap below the rotor, and a water-absorbing sponge is further sleeved on the rotating shaft to absorb leaked liquid.
[0014] The application also provides a centrifuge tube with homogenization function, which comprises a centrifuge tube and a centrifuge tube cover with homogenization function as described above.
[0015] The application has the following technical effects compared with the prior art:
[0016] In the experimental analysis process, more and more homogenization treatment is needed, but in the above experimental process, the customer uses a handheld homogenizer or a full-automatic homogenizer, and the homogenization bottle is completely open. Figure 1 As shown in the figure, toxic and harmful gases will be volatilized during homogenization, which is very harmful to the experimenters. Even if the homogenizer is placed in a fume hood, there is still a risk of gas volatilization, and it will occupy the limited space of the fume hood. After homogenization, the sample in the homogenization bottle needs to be completely transferred to a centrifuge tube for centrifugal separation treatment. The steps are complicated and inefficient.
[0017] The scheme provided by the application realizes homogenization treatment of the detection sample and the extraction reagent directly in the centrifuge tube by using the homogenization assembly in the centrifuge tube cover with homogenization function, and solves the problem of toxic and harmful reagents invading experimenters due to the open homogenization bottle. After homogenization treatment, the cover is removed, and the centrifuge tube can be directly placed in a centrifuge for centrifugal separation. The experimental process is greatly optimized, and the experimental efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS
[0018] In order to more clearly illustrate the technical solutions in the embodiments of the application or the prior art, the drawings needed in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative labor.
[0019] Figure 1 Fig. 1 is a structural schematic diagram of a homogenizer in the prior art;
[0020] Figure 2 、 Figure 3 and Figure 4 are structural schematic diagrams of centrifuge tubes with homogenization function of different types respectively;
[0021] Figure 5 is a structural schematic diagram of a stator and a rotor in a centrifuge tube cover with homogenization function shown in Fig. 2; Figure 2
[0022] Figure 6 is a top view of a centrifuge tube cover with homogenization function shown in Fig. 3; Figure 2
[0023] Figure 7 is a structural schematic diagram of a rotor in a centrifuge tube cover with homogenization function shown in Fig. 4; Figure 3
[0024] Figure 8 is a top view of a centrifuge tube cover with homogenization function shown in Fig. 5; Figure 3
[0025] Figure 9 is a structural schematic diagram of a stator and a rotor in a centrifuge tube cover with homogenization function shown in Fig. 6; Figure 4
[0026] Figure 10 is a top view of a centrifuge tube cover with homogenization function shown in Fig. 7; Figure 4 In the figure: 1 - centrifuge tube; 2 - stator; 3 - rotor; 4 - bearing; 5 - water absorption sponge; 6 - bearing snap spring; 7 - dynamic sealing ring; 8 - motor shaft; 9 - motor; 10 - sample for detection; 11 - extraction reagent; 12 - cover; 13 - static sealing ring; 14 - fixing seat.
[0027] DETAILED DESCRIPTION The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.
[0028]
[0029] The purpose of the present application is to provide a centrifuge tube cover with homogenization function and a centrifuge tube to solve the problems existing in the prior art, solve the problem of toxic and harmful reagents harming experimenters due to the opening of the homogenization bottle during homogenization, and the cumbersome process of transferring the sample in the homogenization bottle to the centrifuge tube for centrifugal separation.
[0030] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the present application will be further described in detail below in combination with the drawings and specific embodiments.
[0031] Figure 1 Figure 1 is a structural schematic diagram of a homogenizer in the prior art.
[0032] Figure 2 、 Figure 3 and Figure 4 are structural schematic diagrams of different types of centrifuge tube covers with homogenization function.
[0033] Embodiment one
[0034] The present embodiment provides a centrifuge tube cover with homogenization function, which comprises a cover body 12 and a homogenization assembly. The cover body 12 is used to cover the opening of a centrifuge tube 1, and the homogenization assembly is used to homogenize the detection sample 10 and the extraction reagent 11 in the centrifuge tube 1.
[0035] In use, the detection sample 10 and the extraction reagent 11 are placed in the centrifuge tube 1, the cover is covered on the centrifuge tube 1 and the centrifuge tube 1 is sealed, the homogenization assembly is started to homogenize the detection sample 10, and after the homogenization is completed, the cover is disassembled and the centrifuge tube 1 is directly placed in the centrifuge for centrifugal separation.
[0036] The scheme provided in the present embodiment realizes homogenization of the detection sample 10 and the extraction reagent 11 in the centrifuge tube 1 by using the homogenization assembly in the centrifuge tube cover with homogenization function, and solves the problem of toxic and harmful reagents harming experimenters due to the opening of the homogenization bottle. After homogenization, the cover is disassembled and the centrifuge tube 1 can be directly placed in the centrifuge for centrifugal separation. The experimental process is greatly optimized and the efficiency of the experiment is improved.
[0037] In some embodiments, the cover body 12 can be detachably connected to the centrifuge tube 1, which can be threaded connection or buckle connection, and can be sealed if necessary to avoid liquid leakage.
[0038] In some embodiments, the homogenizing assembly comprises a stator 2, a rotor 3 and a rotor driving device, the stator 2 and the rotor 3 are arranged on the inner side of the cover body 12, the stator 2 is fixedly arranged, the rotor 3 is rotatable, and the rotor driving device can drive the rotor 3 to rotate relative to the stator 2 and utilize the cutting force and the friction force between the object to homogenize the detection sample 10. Specifically, the stator 2 is arranged in multiple and surrounds the rotor 3; in other embodiments, the side of the stator 2 facing the rotor 3 is provided with friction teeth, which is more conducive to the homogenization effect. The rotor driving device can be a motor.
[0039] As shown in the figure, there are three styles:
[0040] The first one is as shown in Figure 5 and Figure 6 .
[0041] The second one is as shown in Figure 9 and Figure 10 .
[0042] The third one is as shown in Figure 7 and Figure 8 , the stator 2 structure of the third one is the same as the second one, and the rotor 3 structure is different.
[0043] In use, the centrifugal tube 1 needs to be inverted, so that the material in the centrifugal tube 1 flows downward to the stator 2 and the rotor 3, so as to facilitate the homogenization treatment.
[0044] In some embodiments, the centrifugal tube 1 cover is made of PE material or PP material, the stator 2 is made of PE material or stainless steel material, and the rotor 3 is made of PC material or stainless steel material.
[0045] In some embodiments, the rotating shaft of the rotor 3 is supported by the fixedly arranged bearing 4, a dynamic sealing ring 7 is arranged below the rotor 3 to seal the gap below the rotor 3, and a water absorption sponge 5 is further sleeved on the rotating shaft to absorb the leaked liquid.
[0046] Embodiment two
[0047] This embodiment provides another centrifugal tube cover with homogenization function, which is different from embodiment one only in that the homogenizing assembly in this embodiment comprises a crushing blade and a blade driving device, the crushing blade is arranged on the inner side of the cover body 12, and the blade driving device can drive the crushing blade to rotate.
[0048] Embodiment three
[0049] This embodiment provides a centrifugal tube with homogenization function, which comprises a centrifugal tube 1 and the centrifugal tube cover with homogenization function as described in embodiment one, the centrifugal tube 1 is used to contain the detection sample 10 and the extraction reagent 11, and the cover body 12 is used to cover the opening of the centrifugal tube 1.
[0050] The centrifugal tube 1 can adopt the specification in the prior art, that is, as shown in the drawings, the specification at least includes 120ml, 50ml and 25ml. Figures 2 to 4 As the centrifugal tube 1 of different specifications has different thickness, the size of the cover used is also different, in actual application, the centrifugal tube 1 with cover is placed upside down on a fixing frame, the fixing frame has a stepped hole to accommodate the cover, but as the size of the cover is different, in order to install the cover in the stepped hole of the same model, a fixing seat 14 is arranged at the bottom of some covers, the size of the fixing seat 14 is made according to the size of the stepped hole, so as to achieve the purpose of installing the fixing seat 14 in the stepped hole, specifically, as shown in the drawings. Figure 2
[0051] The principle and implementation mode of the present application are described by applying specific examples in the present application, the above embodiment is only used to help understand the method and core idea of the present application; meanwhile, for the general technical personnel in the field, according to the idea of the present application, the specific implementation mode and application range will be changed. In summary, the content of the specification should not be understood as the limitation of the present application.
Claims
1. A centrifuge tube cap having homogenization functionality, characterized by: The application relates to a centrifugal tube cover with a homogenizing function, which comprises a cover body and a homogenizing assembly. The homogenizing assembly can homogenize the detection sample and the extraction reagent in the centrifugal tube to solve the problem that toxic and harmful reagents harm experimenters due to the opening of a homogenizing bottle; the cover body is detachably connected to the centrifugal tube; the homogenizing assembly has two forms, form one: the homogenizing assembly comprises a stator, a rotor and a rotor driving device, the stator and the rotor are arranged on the inner side of the cover body, the stator is fixedly arranged, the rotor can rotate, the stator is arranged in multiple and surrounds the rotor, the rotor driving device can drive the rotor to rotate relative to the stator and utilize the cutting force and the friction force between the object to homogenize the detection sample; form two: the homogenizing assembly comprises a crushing blade and a blade driving device, the crushing blade is arranged on the inner side of the cover body, and the blade driving device can drive the crushing blade to rotate. In use, the centrifugal tube is inverted.
2. The centrifuge tube cover with homogenization function according to claim 1, characterized in that: The centrifugal tube cover is made of PE or PP, the stator is made of PE or stainless steel, and the rotor is made of PC or stainless steel.
3. The centrifuge tube cover with homogenization function according to claim 1, characterized in that: The side of the stator facing the rotor is provided with friction teeth.
4. The centrifuge tube cover with homogenization function according to claim 1, characterized in that: The rotating shaft of the rotor is supported by a fixed bearing, a dynamic sealing ring is arranged below the rotor to seal the gap below the rotor, and a water-absorbing sponge is further sleeved on the rotating shaft to absorb leaked liquid.
5. The centrifuge tube cover with homogenization function according to claim 1, characterized in that: The application further relates to a centrifugal tube and the centrifugal tube cover with a homogenizing function according to any one of claims 1-5.
6. A centrifuge tube having homogenization functionality, characterized by:
Citation Information
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