RNAi molecules lethal to radish aphids

By designing RNAi molecules and synergistic formulas targeting the ATP synthase gene of radish aphids, we developed highly efficient and environmentally friendly RNAi pesticides, which solved the problems of pesticide resistance and environmental pollution caused by chemical pesticides and achieved effective prevention and control of radish aphids and sustained efficacy.

CN116024209BActive Publication Date: 2025-09-23SHANGHAI PLANT SCI BIOTECHNOLOGY LTD
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Patent Information

Application Number
CN202111239560.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-10-25
Publication Date
2025-09-23
Estimated Expiration
2041-10-25

AI Technical Summary

Technical Problem

Existing technologies mainly rely on chemical pesticides to control radish aphid pests, which leads to increased pesticide resistance and environmental pollution. There is an urgent need to develop new and efficient control methods.

Method used

We designed and used RNAi molecules targeting the ATP synthase gene LeATPf of radish aphid, combined with a synergistic formula, to prepare RNAi pesticides for inhibiting the growth and reproduction of radish aphids.

Benefits of technology

The lethality rate of RNAi pesticides on radish aphids is as high as 81%, and the expression level of the LeATPf gene is reduced by 76%. The drug's efficacy is more sustained than that of traditional chemical pesticides such as imidacloprid and is environmentally friendly.

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Abstract

The present invention discloses an RNAi molecule for inhibiting the ATP synthase gene of radish aphids, which is a double-stranded RNA molecule consisting of a sense strand and a complementary antisense strand, wherein the nucleotide sequence of the sense strand is SEQ ID NO: 2. RNAi pesticides containing the RNAi molecule can effectively kill radish aphids.
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Citation Information

Patent Citations

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