A pulsed ablation device

Abstract

The application discloses a kind of pulse ablation devices, including main pipe body, self-expanding stent, hard guide wire, at least one ablation electrode and at least one electrode pin;The distal end of main pipe body is connected with the proximal end of self-expanding stent, and the distal end of main pipe body is provided with first opening, and the proximal end of main pipe body is provided with second opening communicated with first opening;Hard guide wire is through in main pipe body, and the distal end of hard guide wire is in abutment with the distal end of self-expanding stent, and self-expanding stent can be driven by hard guide wire and be switched from unfolded state to shrinkage state, and be automatically switched from shrinkage state to unfolded state when there is no hard guide wire driving;Self-expanding stent has maximum diameter in unfolded state, and has minimum diameter in shrinkage state, and maximum diameter is greater than the diameter of main pipe body;Ablation electrode is arranged in main pipe body and is close to the distal end of main pipe body, and ablation electrode is electrically connected with electrode pin.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a pulse ablation device. Background Technology

[0002] Benign prostatic hyperplasia (BPH) is a common disease in elderly men. BPH is caused by cell proliferation, not cell hypertrophy. Strictly speaking, BPH is a histopathological diagnosis. Clinically, it often leads to prostate enlargement, which can cause bladder outlet obstruction, ultimately resulting in a series of lower urinary tract symptoms (LUTS) associated with lower urinary tract obstruction. Clinical statistics show that due to improved quality of life, the demand for surgical efficacy is increasing. Previously, the need to simply address prostate hyperplasia has expanded to include postoperative recovery time and preservation of prostate function and nerves.

[0003] Currently, the main treatments for benign prostatic hyperplasia (BPH) include medication, surgery, and interventional procedures. The BPH treatment guidelines state that transurethral resection of the prostate (TURP) is the gold standard and the primary surgical procedure used by doctors. However, this surgery can damage prostate blood vessels and nerves, leading to significant bleeding, postoperative hematuria, a long recovery time, and potential impairment of sexual function. Besides TURP, there are many other new surgical treatments, such as radiofrequency ablation, microwave ablation, laser ablation, and cryotherapy. These methods utilize high or low temperatures to destroy the hyperplastic tissue, achieving the therapeutic goal.

[0004] Unlike thermotherapy, pulsed electroporation utilizes the theory of irreversible electroporation. Unlike physical therapies based on thermal ablation, such as radiofrequency, microwave, cryotherapy, and focused ultrasound, this technology applies a high-voltage pulsed electric field with a microsecond-level pulse width around the target cells. This disrupts the stability of the tumor cell membrane surface, creating multiple hydrophilic micropores, thereby disrupting cell homeostasis and ultimately leading to cell death. This technology can selectively kill diseased tissue while effectively preserving the blood vessels and nerves of the prostate, thus reducing postoperative hematuria and preserving prostate function. Currently, irreversible electroporation can be used to treat benign prostatic hyperplasia in two ways:

[0005] Firstly, there's the percutaneous puncture technique. This technique involves inserting a needle into the body under the guidance of imaging equipment. On one hand, percutaneous puncture requires X-ray or CT scans for localization; the use of CT imaging equipment exposes both the patient and medical staff to strong radiation. On the other hand, the puncture process heavily relies on the surgeon's skill and experience. The prostate and surrounding areas have a dense network of blood vessels and nerves; even slight mistakes can puncture blood vessels and nerves, leading to prostate bleeding or nerve damage, causing unnecessary secondary injury. Furthermore, for patients with irregularly located prostates, external puncture localization is more difficult.

[0006] Secondly, there is the transurethral puncture technique. This technique also heavily relies on the surgeon's skill and experience. Furthermore, most transurethral products require the use of an endoscope to locate the prostate and insert it into the enlarged prostate area through a natural orifice (urethra or rectum) for treatment. This method requires a relatively large delivery system, causing considerable pain for the patient. This procedure is particularly inadvisable for patients with urethral stricture. With the use of irreversible electroporation techniques, there is also the possibility of electromagnetic interference between the two active devices, leading to prolonged procedure time and reduced safety. Summary of the Invention

[0007] In view of the shortcomings of the prior art described above, the pulse ablation device provided in this application embodiment can achieve precise positioning and ablation without the aid of external imaging products.

[0008] This invention provides a pulse ablation device, comprising a main body, a self-expanding support, a rigid guidewire, at least one ablation electrode, and at least one electrode pin;

[0009] The distal end of the main tube is connected to the proximal end of the self-expanding stent. The distal end of the main tube has a first opening, and the proximal end of the main tube has a second opening, which communicates with the first opening. The rigid guidewire passes through the main tube, and the distal end of the rigid guidewire can abut against the distal end of the self-expanding stent. The self-expanding stent can be driven by the rigid guidewire to switch from an extended state to a retracted state, and can automatically switch from a retracted state to an extended state when there is no rigid guidewire driving it. The self-expanding stent has a maximum diameter in the extended state and a minimum diameter in the retracted state, and the maximum diameter is greater than the diameter of the main tube.

[0010] The at least one ablation electrode is disposed within the main body and near the distal end of the main body, and the ablation electrode is electrically connected to the electrode pin.

[0011] Furthermore, the self-expanding support includes a plurality of self-expanding elements arranged circumferentially around the axis of the main body. The proximal ends of the plurality of self-expanding elements are connected to the distal ends of the main body, and the distal ends of the plurality of self-expanding elements converge toward the axis of the main body. The diameter of the self-expanding elements gradually increases from both ends toward the middle.

[0012] Furthermore, the self-expanding element is made of shape memory material.

[0013] Furthermore, the self-expanding element is made of memory silicone material.

[0014] Furthermore, the proximal end of the rigid guidewire extends beyond the proximal end of the main tube.

[0015] Furthermore, it also includes an axial limiting structure, which is used to define the relative position of the rigid guidewire and the main body in the axial direction of the main body.

[0016] Furthermore, the axial limiting structure includes a first mating limiting part and a second mating limiting part. The first mating limiting part is disposed at the proximal end of the rigid guidewire, and the second mating limiting part is disposed at the proximal end of the main body. The rigid guidewire and the main body can be limited by the first mating limiting part and the second mating limiting part.

[0017] Furthermore, the main body is provided with a liquid level observation section, the distal end of which is close to the proximal end of the ablation electrode, and the proximal end of which is close to the proximal end of the main body. The liquid level observation section is used to observe the liquid level inside the main body.

[0018] Furthermore, the plurality of ablation electrodes are spaced apart along the axial direction of the main body.

[0019] Furthermore, it also includes at least one ablation controller disposed outside the main body, and the ablation electrode is electrically connected to the electrode pin.

[0020] Furthermore, it also includes a branch pipe body, one end of which is connected to the side wall of the main pipe body, and the other end of which is provided with the electrode pin.

[0021] The implementation of this invention has the following beneficial effects:

[0022] This invention provides a pulse ablation device that utilizes the pressure difference between the inside and outside of the bladder to determine the product's location. It then uses the position of the prostate and bladder to pinpoint the area of ​​prostate tissue to be ablated. This allows for precise ablation without the aid of external imaging equipment, avoiding electromagnetic interference during pulse generation and improving the safety and effectiveness of the procedure. Furthermore, the device can also be used directly as a urinary catheter, remaining in the body for 7 days. If further treatment is needed, it can be directly connected to a pulse cable for pulse emission therapy without requiring further intervention.

[0023] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0024] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 This is a schematic diagram of an unfolded state of the pulse ablation device provided in an embodiment of the present invention;

[0026] Figure 2 This is a schematic diagram of a contracted state of the pulse ablation device provided in an embodiment of the present invention;

[0027] Figure 3 This is a schematic diagram of the pulse ablation device provided in this embodiment of the invention in vivo;

[0028] Figure 4 This is a partial structural schematic diagram of the self-expanding stent obtained from the distal end to the proximal end, provided by an embodiment of the present invention;

[0029] Figure 5 This is a schematic diagram of another unfolded state of the pulse ablation device provided in an embodiment of the present invention.

[0030] Among them, 1-main tube, 2-self-expanding stent, 21-self-expanding element, 3-rigid guide wire, 4-ablation electrode, 5-axial limiting structure, 51-first mating limiting part, 52-second mating limiting part, 6-ablation controller, 7-branch tube, 8-prostate, 9-bladder, 91-urine. Detailed Implementation

[0031] The technical solutions in the embodiments of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0032] The term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. In the description of the present invention, it should be understood that the terms "upper," "lower," "left," "right," "top," "bottom," etc., indicating orientation or positional relationships based on the orientation or positional relationships shown in the accompanying drawings, are used only for the convenience of describing the present invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.

[0033] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. Moreover, the terms "first," "second," etc., are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that embodiments of the invention described herein can be implemented in orders other than those illustrated or described herein.

[0034] The pulsed ablation device provided in this embodiment of the invention can be used for prostate ablation treatment. However, the invention is not limited thereto; the technical solution provided in this embodiment can also be used to ablate other physiological structures with similar structural and positional relationships to the bladder and prostate. The following description uses prostate ablation as an example, with the end of the main tube closer to the patient as the distal end and the end closer to the operator as the proximal end.

[0035] like Figure 1 and Figure 2 As shown, an embodiment of the present invention provides a pulse ablation device comprising a main body 1, a self-expanding stent 2, a rigid guidewire 3, at least one ablation electrode 4, and at least one electrode pin. The distal end of the main body 1 is connected to the proximal end of the self-expanding stent 2. The distal end of the main body 1 has a first opening, and the proximal end of the main body 1 has a second opening communicating with the first opening. The rigid guidewire 3 passes through the main body 1, and the distal end of the rigid guidewire 3 can abut against the distal end of the self-expanding stent 2. The self-expanding stent 2 can be driven by the rigid guidewire 3 as follows: Figure 1 The unfolded state shown is switched to as follows Figure 2The contracted state shown, and the automatic switching from the contracted state to the expanded state when there is no rigid guide wire 3 driving; at least one ablation electrode 4 is disposed in the main body 1 and near the distal end of the main body 1, and the ablation electrode 4 is electrically connected to the electrode pin.

[0036] Existing ablation procedures require the use of an endoscope, increasing the size of the transurethral intervention and patient discomfort, especially for patients with urinary tract strictures, making the procedure impossible. The pulse ablation device provided in this invention eliminates the need for compatibility with endoscope channels or endoscopic intervention in the urethra. Furthermore, the self-expanding stent 2 remains in a contracted state during the insertion of the main conduit into the urethra. Compared to existing methods using endoscopic surgery, this solves the problem of excessively large maximum insertion diameter of interventional products, improves patient experience, has a wider range of applications, and avoids electromagnetic interference during pulse generation, resulting in better safety.

[0037] Existing ablation procedures involve using an endoscope to observe whether instruments have reached the prostate before initiating ablation. In this embodiment of the invention, the distal end of the main tube 1 has a first opening, and the proximal end has a second opening communicating with the first opening. The distal end of the main tube 1 enters the urethra through the urethral opening. When inserted into the urethra, it can be observed that there is currently no urine in the tube. When the self-expanding stent reaches the bladder, the internal pressure of the bladder causes urine to flow from the self-expanding stent along the main tube 1 until the pressure inside the bladder and outside the tube are balanced, at which point the urine reaches a stable state inside and outside the main tube 1. At this point, the operator can determine whether the self-expanding stent 2 has reached the bladder position by judging the urine backflow in the main tube 1. This allows for positioning using the pressure difference between the inside and outside of the bladder. When urine is observed flowing out of the main tube 1, it can be determined that the distal self-expanding stent has reached the bladder position, making the operation more convenient.

[0038] The principle of using the pressure difference between the inside and outside of the bladder for localization is as follows:

[0039] Urinating is primarily mediated by the urethral sphincter and detrusor muscle. When there is urine in the bladder, the pressure inside the bladder is greater than the external pressure. The sphincter acts like a valve; if it is closed, urination cannot occur. If the sphincter opens, the pressure difference between the bladder and the outside world allows urine to be expelled smoothly through the urethra. In most cases, during urination, the sphincter opens, and the detrusor muscle simultaneously works (creating a greater pressure difference). Together, they successfully expel urine from the body.

[0040] This invention utilizes the pressure difference within the bladder when urine is present. When the product is inserted into the urethra and reaches the bladder, the normally closed sphincter opens. Urine then flows out along the urethra. When the operator sees urine overflowing from the main body 1, they can determine that the bladder has been reached.

[0041] At this point, pull the rigid guide wire 3 to open the distal self-expanding body. When you feel external resistance when gently pulling the main tube 1, you can confirm that the positioning is complete.

[0042] In existing ablation procedures, after tissue ablation, doctors insert a urinary catheter into the patient's urethra to facilitate urination. Due to the nature of pulses, it is impossible to immediately determine whether the tissue has been completely ablated during the procedure; the ablation effect is generally visible 7 days post-procedure. If a follow-up examination reveals incomplete ablation, the patient requires another interventional procedure. The pulse ablation device provided in this invention can be used directly as a urinary catheter, remaining in the body for 7 days. Doctors can observe the tissue ablation and metabolism, and if further treatment is needed, they can directly connect the pulse wiring for pulse emission therapy.

[0043] Specifically, the self-expanding support 2 has a maximum diameter and a minimum length in its deployed state, with the maximum diameter being larger than the diameter of the main tube 1, such as... Figure 1 As shown, in its unfolded state, the two ends of the self-expanding support 2 are closed and the middle is expanded, and the outer contour of the self-expanding support 2 is roughly basket-shaped. The self-expanding support 2 can also be other structures, such as spherical, egg-shaped, pumpkin-shaped, lantern-shaped, elliptical, etc.

[0044] Specifically, the self-expanding stent 2 has a minimum diameter and a maximum length in the contracted state, such as Figure 2 As shown, in the contracted state, the distal end of the self-expanding stent 2 is held in place by the rigid guidewire 3. Both ends and the middle of the self-expanding stent 2 are retracted inward, and the self-expanding stent 2 is in a straight or nearly straight state, which facilitates reaching the target position. When the pulse ablation device reaches the target position (i.e., the first opening reaches the bladder neck), the axial restraint and external force on the rigid guidewire 3 are removed. At this time, the rigid guidewire 3 is no longer held forward by external force, and the self-expanding stent will return to its original open shape and be fixed at the bladder neck, as specifically... Figure 3 As shown.

[0045] It should be noted that the self-expanding support 2 has a hollow interior and no spindle, making it an independent structure.

[0046] Because urinary catheters need to remain in the bladder for at least 7 days, many current designs use balloon positioning or direct catheter insertion. The distal end of the catheter is positioned a certain distance from the bladder neck. Urine can only flow out when it accumulates in the bladder to a height higher than the distal catheter's protrusion from the balloon. The portion of urine below this height remains in the bladder, and over time, scale buildup can easily occur at the junction of the balloon and the bladder. Furthermore, prolonged urine accumulation can easily lead to cystitis, and the constant contact between the urethra and the catheter can also cause urethral scaling and inflammation. Please continue reading... Figure 3In this embodiment of the invention, the proximal end of the self-expanding body is connected to the distal end of the main tube 1, and the position of the bladder neck directly corresponds to the position of the first opening. Urine 91 flows into the main tube 1 through the first opening, thereby solving the problem of urine 91 easily accumulating in the trigone area (bladder neck) of the bladder 9, which helps to avoid urine 91 scaling and reduce the risk of bladder 9 and urethral complications. Figure 2 As shown, the first opening is preferably located at the distal end of the main body 1.

[0047] Preferably, the rigid guidewire 3 is coaxially inserted into the main tube body 1. The rigid guidewire 3 has the function of supporting and guiding the main tube body 1. Placing the rigid guidewire 3 inside the main tube body 1 makes it easier for the main tube body 1 to penetrate the urethra and smoothly slide into the bladder 9 through the lower urinary tract obstruction caused by diseases such as benign prostatic hyperplasia and urethral stricture.

[0048] Preferably, please continue to refer to Figure 1 and Figure 2 The second opening is located at the proximal end of the main tube 1. The distal end of the rigid guidewire 3 can abut against the distal end of the self-expanding stent 2 through the first opening, and partially or completely extend from the proximal end of the main tube 1 through the second opening. The rigid guidewire 3 can move axially relative to the main tube 1 under the action of external force, thereby causing the self-expanding stent 2 to expand or contract radially.

[0049] Preferably, the self-expanding support 2 includes a plurality of self-expanding elements 21 arranged circumferentially around the axis of the main tube 1, such as... Figure 1 and 4 As shown, a gap is formed between adjacent self-expanding elements 21 to allow liquid to pass through, and the plurality of self-expanding elements 21 are enclosed to form a structure that can contract and expand radially. The proximal ends of the plurality of self-expanding elements 21 are connected to the distal ends of the main body 1, and the distal ends of the plurality of self-expanding elements 21 converge toward the axis of the main body 1. The diameter of the self-expanding elements 21 gradually increases from both ends toward the middle.

[0050] Existing urinary catheters are equipped with a balloon. By inflating the balloon, it is fixed in place at the bladder neck within the bladder, preventing the catheter from moving and thus securing it. Please continue reading... Figure 3 Compared with the prior art, the pulse ablation device of the present invention uses a self-expanding stent 2 instead of a balloon to reduce the contact area between the stent and the bladder 9, which helps to reduce the occurrence of bladder 9 inflammation due to long-term close contact.

[0051] Preferably, the outer wall of the main tube 1 is provided with a groove to reduce the contact area between the outer wall of the main tube 1 and the urethra, which helps to reduce the occurrence of urethritis caused by long-term close contact.

[0052] Figure 4The self-expanding support 2 shown has four self-expanding elements 21 arranged circumferentially around the axis of the main tube 1. In some other embodiments, the number of self-expanding elements 21 may be three, five, six, seven, eight, or any other suitable number. The self-expanding elements 21 can be as follows: Figure 4 The arrangement shown is preferably uniform along the circumference, but it can also be non-uniform.

[0053] Preferably, the self-expanding support 2 has a symmetrical structure, with multiple sets of self-expanding elements 21 arranged symmetrically about the axis of the main body 1. Here, "symmetry" includes not only theoretical complete symmetry but also approximate symmetry that tends towards symmetry.

[0054] Optionally, the distal end of the self-expanding support 2 is composed of interconnected self-expanding elements 21.

[0055] Optionally, the self-expanding element 21 is made of shape memory material. The shape memory material can be a shape memory alloy or a polymer elastomer, preferably a shape memory silicone material. Using silicone for the self-expanding element 21 allows the self-expanding stent 2 to more gently enter the urethra and reach the bladder, avoiding damage to the urethra and improving patient comfort.

[0056] Alternatively, the expansion element can be pre-formed and then fixed to the expansion bracket.

[0057] Preferably, the distal end of the self-expanding stent 2 is further provided with a positioning structure; the positioning structure has a limiting part and a connecting part, the limiting part is used to limit the distal end of the rigid guide wire 3 that abuts against it in the radial direction, and the connecting part is used to connect with the distal end of the self-expanding element 21, the radial dimension of the connecting part is not greater than the radial dimension of the middle part of the self-expanding stent 2.

[0058] Preferably, the proximal end of the rigid guidewire 3 extends beyond the proximal end of the main tube 1. By pulling the proximal end of the rigid guidewire 3, the rigid guidewire 3 can be moved from the distal end to the proximal end; by pushing the proximal end of the rigid guidewire 3, the rigid guidewire 3 can be moved from the proximal end to the distal end. The structure is simple and easy to operate.

[0059] Preferably, it also includes an axial limiting structure 5, which is used to limit the relative position of the rigid guide wire 3 and the main body 1 in the axial direction of the main body 1 so that the self-expanding support 2 is in a contracted state, without the need for manual pressing of the limiting structure, which is convenient for operation.

[0060] Furthermore, the axial limiting structure 5 includes a first engaging limiting part 51 and a second engaging limiting part 52. The first engaging limiting part 51 is disposed at the proximal end of the rigid guide wire 3, and the second engaging limiting part 52 is disposed at the proximal end of the main body 1. The rigid guide wire 3 and the main body 1 can be limited by the engagement of the first engaging limiting part 51 and the second engaging limiting part 52. For example, the first engaging limiting part 51 can be an internal thread, and the second engaging limiting part 52 can be an external thread; for example, the first engaging limiting part 51 can be a limiting protrusion, and the second engaging limiting part 52 can be a limiting groove; the axial limiting structure 5 can also be a bayonet device, and other structures that can limit the rigid guide wire 3 and the main body 1 in the axial direction can also be applied herein.

[0061] Specifically, the main body 1 is provided with a liquid level observation section. The distal end of the liquid level observation section is close to the proximal end of the ablation electrode 4, and the proximal end of the liquid level observation section is close to the proximal end of the main body 1. The liquid level observation section is used to observe the liquid level inside the main body 1. Optionally, the liquid level observation section covers at least a portion of the proximal area of ​​the main body 1, and this portion is a light-transmitting area; preferably, the light-transmitting area can be a transparent area, a semi-transparent area, etc.

[0062] In one embodiment, multiple ablation electrodes 4 are spaced apart along the axial direction of the main body 1, thus adapting to ablation targets of different locations and sizes. For example, a first ablation electrode 4 is placed at a first preset distance from the proximal end of the self-expanding body, followed by an ablation electrode 4 placed at every second preset distance. The first preset distance can be 2-8 mm; for example, the first preset distance is 2 mm, 5 mm, or 8 mm. The second preset distance can also be 2-8 mm; for example, the first preset distance is 2 mm, 5 mm, or 8 mm. It should be noted that the values ​​of the first and second preset distances can be adjusted according to actual needs, and this embodiment is not limited thereto.

[0063] It should be noted that the electrode can be a ring electrode, a sheet electrode, a point electrode, or a spherical electrode, etc., and this embodiment does not make any specific limitation.

[0064] In one embodiment, such as Figure 4 and 5 As shown, the pulse ablation device also includes at least one ablation controller 6, which is disposed outside the main body 1, and the ablation electrode 4 is electrically connected to the electrode pins. Please refer to [link / reference needed]. Figure 5 When it is determined that the product has reached the target position, that is, the first opening is located at the bladder neck, the position range of the prostate 8 to be ablated is located by the position of the prostate 8 and the bladder 9, and the corresponding ablation electrode 4 is controlled by the corresponding ablation controller 6 to perform pulse ablation.

[0065] In one embodiment, the pulse ablation device further includes a branch tube 7, one end of which communicates with the side wall of the main tube 1, and the other end of which is provided with electrode pins. Figure 5 As shown, the electrodes flow along the main body 1 and finally branch to the branch body 7. The electrode pins on the branch body 7 are connected to the corresponding positions on the controller by wires.

[0066] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0067] As can be seen from the embodiments of the pulse ablation device provided by the present invention, the pulse ablation device provides by the present invention utilizes the pressure difference inside and outside the bladder to determine the position of the product, and then locates the range of prostate ablation tissue by the position of the prostate and bladder. Thus, precise positioning and ablation can be achieved without the aid of external imaging products, avoiding electromagnetic interference during pulse generation and improving the safety and effectiveness of the surgery. Simultaneously, the device can also be used directly as a urinary catheter, remaining in the body for 7 days. If further treatment is needed, it can be directly connected to the pulse wiring for pulse emission therapy without further intervention.

[0068] The above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

[0069] The above are merely preferred embodiments of the present invention and are not intended to limit the invention. It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from its spirit or essential characteristics. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of the invention is defined by the appended claims rather than the foregoing description, and all variations falling within the meaning and scope of equivalents of the claims are intended to be included within the invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0070] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A pulse ablation device, characterized in that, It includes a main body (1), a self-expanding stent (2), a rigid guidewire (3), at least one ablation electrode (4), and at least one electrode pin; The self-expanding support (2) includes a plurality of self-expanding elements (21) arranged circumferentially around the axis of the main body (1), and a gap is formed between adjacent self-expanding elements (21) to allow liquid to pass through. The distal end of the main tube (1) is connected to the proximal end of the self-expanding stent (2). The distal end of the main tube (1) is provided with a first opening, and the proximal end of the main tube (1) is provided with a second opening. The second opening communicates with the first opening. The first opening can abut against the position of the bladder neck. Urine in the bladder can enter the main tube (1) through the first opening and flow out through the second opening. The rigid guidewire (3) passes through the main tube (1). The distal end of the rigid guidewire (3) can abut against the distal end of the self-expanding stent (2). The self-expanding stent (2) can switch from an extended state to a contracted state driven by the rigid guidewire (3), and automatically switch from a contracted state to an extended state when there is no rigid guidewire (3). The self-expanding stent (2) has a maximum diameter in the extended state and a minimum diameter in the contracted state. The maximum diameter is greater than the diameter of the main tube (1). The at least one ablation electrode (4) is disposed inside the main body (1) and near the distal end of the main body (1), and the ablation electrode (4) is electrically connected to the electrode pin; The proximal ends of the plurality of self-expanding elements (21) are connected to the distal ends of the main tube (1). The distal ends of the plurality of self-expanding elements (21) converge toward the axis of the main tube (1). The diameter of the self-expanding elements (21) gradually increases from both ends toward the middle. The pulse ablation device can be used as a catheter. The main tube (1) is provided with a liquid level observation section. The distal end of the liquid level observation section is close to the proximal end of the ablation electrode. The proximal end of the liquid level observation section is close to the proximal end of the main tube (1). The liquid level observation section is used to observe the liquid level in the main tube (1). It also includes a branch tube (7). One end of the branch tube (7) is connected to the side wall of the main tube (1). The other end of the branch tube (7) is provided with the electrode pin. A rigid guidewire is coaxially inserted into the main tube body. A second opening is located at the proximal end of the main tube body. The distal end of the rigid guidewire can abut against the distal end of the self-expanding support through the first opening. It extends partially or completely from the proximal end of the main tube body through the second opening. A groove is provided on the outer wall of the main tube body. The proximal end of the rigid guidewire extends out of the proximal end of the main tube body. The distal end of the self-expanding support is also provided with a positioning structure. The positioning structure has a limiting part and a connecting part. The limiting part is used to limit the distal end of the rigid guidewire that abuts against it in the radial direction. The connecting part is used to connect with the distal end of the self-expanding element. The radial dimension of the connecting part is not greater than the radial dimension of the middle part of the self-expanding support.

2. The pulse ablation device according to claim 1, characterized in that, The self-expanding element (21) is made of shape memory material.

3. The pulse ablation device according to claim 2, characterized in that, The self-expanding element (21) is made of memory silicone material.

4. The pulse ablation device according to claim 1, characterized in that, It also includes an axial limiting structure (5), which is used to define the relative position of the rigid guide wire (3) and the main body (1) in the axial direction of the main body (1).

5. The pulse ablation device according to claim 4, characterized in that, The axial limiting structure (5) includes a first mating limiting part (51) and a second mating limiting part (52). The first mating limiting part (51) is disposed at the proximal end of the rigid guidewire (3), and the second mating limiting part (52) is disposed at the proximal end of the main body (1). The rigid guidewire (3) and the main body (1) can be limited by the first mating limiting part (51) and the second mating limiting part (52).

6. The pulse ablation device according to claim 1, characterized in that, The plurality of ablation electrodes (4) are spaced apart along the axial direction of the main body (1).

7. The pulse ablation device according to claim 1, characterized in that, It also includes at least one ablation controller (6), which is disposed outside the main body (1), and the ablation electrode (4) is electrically connected to the electrode pin.

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