Nanofiber hand mask and method of preparing the same

Abstract

The application discloses a kind of nanofiber hand film and preparation method thereof, comprising: water-soluble polymer and efficacy component, and the nanofiber hand film is changed into gel state when reacting with oil compound in use;Wherein, the water-soluble polymer is nanofiber structure.The nanofiber hand film provided by the application is obtained by electrospinning technology, and the electrospinning fiber has the advantages of small diameter, high specific surface area, small pore size and high porosity, so that the efficacy component of nanofiber hand film can be long-acting and sustained-release on the skin, and achieve excellent care effect.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of skin care products, in particular to a nanofiber hand film and a preparation method thereof. BACKGROUND

[0002] In daily life, due to a large amount of work and external factors, the skin aging and roughening speed of hands is relatively fast, and color spots are easily grown on the back of hands. The hand film can deeply nourish the skin, repair the damaged skin due to environmental pollution and sun exposure, and has effects on wrinkles, dry lines and other problems on the skin caused by oxidation.

[0003] However, the current hand film has a relatively cumbersome use method, and it is difficult to achieve rapid and efficient skin care. SUMMARY

[0004] In view of the above deficiencies of the prior art, the present application provides a nanofiber hand film and a preparation method thereof, aiming to solve the problem that the current hand film has a relatively cumbersome use method and it is difficult to achieve rapid and efficient skin care.

[0005] To achieve the above-mentioned purpose, the present application provides a solid film essence, which comprises: a water-soluble polymer and an efficacy component, the nanofiber hand film is reacted with an oil compound to become a gel state when in use; wherein the water-soluble polymer is a nanofiber structure.

[0006] Optionally, the mass of the water-soluble polymer accounts for 8%-12% of the mass of the nanofiber hand film.

[0007] Optionally, the water-soluble polymer comprises at least one of PVA, PEO and PVP.

[0008] Optionally, the efficacy component comprises at least one of a moisturizing component, a skin-soothing component, an anti-wrinkle component, an antibacterial component and a whitening component.

[0009] Optionally, the moisturizing component comprises at least one of hyaluronic acid and biological sugar gum; and / or the skin-soothing component comprises at least one of menthol and a cooling agent; and / or the anti-wrinkle component comprises at least one of Hamamelis virginiana, Centella asiatica extract, aloe vera extract, grape seed extract, polypeptide, oligopeptide and retinoic acid; and / or the antibacterial component comprises at least one of vitamin C, soothing peptide and propolis; and / or the whitening component comprises at least one of niacinamide and arbutin.

[0010] To achieve the above-mentioned purpose, the present application further provides a preparation method of the above-mentioned nanofiber hand film, comprising the following steps: mixing a water-soluble polymer, an efficacy component and deionized water, stirring to obtain a spinning precursor solution; adding the spinning precursor solution into an electrospinning equipment for treatment, and then drying to obtain a nanofiber hand film.

[0011] Optionally, in the step of "mixing the water-soluble polymer, the efficacy ingredient and the deionized water, stirring, obtaining the spinning precursor solution", the efficacy ingredient comprises at least one of the following: a moisturizing ingredient, a skin-soothing ingredient, an anti-wrinkle ingredient, an antibacterial ingredient and a whitening ingredient.

[0012] Optionally, the moisturizing ingredient comprises at least one of the following: hyaluronic acid, biological sugar gum; and / or, the skin-soothing ingredient comprises at least one of the following: menthol, a cooling agent; and / or, the anti-wrinkle ingredient comprises at least one of the following: Hamamelis virginiana, Centella asiatica extract, aloe vera extract, grape seed extract, polypeptide, oligopeptide, retinoic acid; and / or, the antibacterial ingredient comprises at least one of the following: vitamin C, soothing peptide, propolis; and / or, the whitening ingredient comprises at least one of the following: niacinamide, arbutin.

[0013] Optionally, in the step of "mixing the water-soluble polymer, the efficacy ingredient and the deionized water, stirring, obtaining the spinning precursor solution", the electrospinning device is set at a voltage of 15kV-18kV; and / or, the electrospinning device is set at a temperature of 10-45 degrees Celsius; and / or, the electrospinning device is set at an automatic liquid supply speed of 0.5-1ml / h.

[0014] The nano-fiber hand film provided by the application is obtained by electrospinning technology. Under the action of high-voltage electric field, the fiber-like solution is rapidly stretched in the solidification process, and the fiber has good orientation and strength. Therefore, the electrospinning fiber has the advantages of small diameter, high specific surface area, small pore size and high porosity, so that the efficacy ingredient of the nano-fiber hand film can be better dispersed and synergistically act on the skin of the hand. In the use process, an oil compound can be applied first, the skin of the hand is fully massaged to make the pores in an expanded state, and then the nano-fiber hand film is applied. The nano-fiber hand film and the oil compound form a gel, adhere to the skin, and release the efficacy ingredient, which is long-acting and slow-releasing, and is more conducive to people to quickly and efficiently protect the skin in the fragmented time. Moreover, the nano-fiber hand film provided by the application does not add preservatives, has no preservative sensitization problem, and is more environmentally friendly than traditional skin care films. BRIEF DESCRIPTION OF DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or prior art description. Obviously, the drawings in the following description only some embodiments of the present application, and for those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0016] Figure 1A scanning electron microscope image of the nanofiber hand film prepared for a specific embodiment of the present application has a magnification of 10,000 times.

[0017] Figure 2 A scanning electron microscope image of the nanofiber hand film prepared for another specific embodiment of the present application has a magnification of 20,000 times.

[0018] The purposes, functional features and advantages of the present application will be further described with reference to the accompanying drawings in conjunction with embodiments. DETAILED DESCRIPTION

[0019] In order to make the purposes, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be described clearly and completely below, and it should be understood that the following embodiments are only used to explain the present application and not used to limit the present application.

[0020] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the claimed subject matter belongs.

[0021] In order to facilitate understanding of the embodiments, the following explains the symbolic terms:

[0022] PVA (Polyvinyl Alcohol) is polyvinyl alcohol, PEO (Poly Ethlene Oxide) is polyethylene oxide, and PVP (Polyvinyl Pyrrolidone) is polyvinyl pyrrolidone.

[0023] Ordinary hands are subjected to a large amount of work and external factors, and the skin aging and roughening speed is also relatively fast, and color spots are also easily grown on the back of the hand. The hand film can deeply nourish the skin and repair the damaged skin due to environmental pollution and sun exposure, and has an effect on wrinkles, dry lines and other problems on the skin caused by oxidation.

[0024] However, the current hand film has a relatively complicated use method, and it is difficult to achieve rapid and efficient skin care.

[0025] To solve the above problems, the present application provides a nanofiber hand film comprising: a water-soluble polymer and an efficacy component, wherein the nanofiber hand film reacts with an oil compound to become a gel state when used; and wherein the water-soluble polymer is in a nanofiber structure. In an embodiment, the water-soluble polymer forms a three-dimensional network structure after being crosslinked with the efficacy component, so that the intermolecular force is enhanced, and the film strength is improved, and the nanofiber hand film swells when in contact with the oil compound, and exhibits a gelable feature. The water-soluble polymer forms a nanofiber structure by an electrospinning method, and has high porosity, good pore connectivity, and strong uniformity of fiber diameter, which can improve the dispersibility of the efficacy component on the surface and in the pores of the nanofiber, and the active ingredient exists in the nanofiber in the form of a small particle, and has a higher dissolution or release efficiency. The nanofiber as a carrier has a large specific surface area and a porous structure, and has a strong mutual penetration with other substances, which is extremely beneficial to the diffusion and dissolution of the efficacy component, and improves the transdermal permeation amount and the transdermal absorption of the efficacy component.

[0026] Further, the mass of the water-soluble polymer accounts for 8%-12% of the mass of the nanofiber hand film. In an embodiment, the higher the concentration of the water-soluble polymer solution, the greater the viscosity and the surface tension, and the droplet breakup ability after leaving the nozzle decreases with the increase of the surface tension. Generally, when other conditions are constant, the fiber diameter increases with the increase of the concentration.

[0027] Further, the water-soluble polymer comprises at least one of PVA, PEO, and PVP. In an embodiment, PVA is selected as the main electrospinning material, and the PVA has good biocompatibility and degradability, and good film-forming and mechanical properties.

[0028] Further, the efficacy component comprises at least one of a moisturizing component, a skin-soothing component, an anti-wrinkle component, an antibacterial component, and a whitening component. In an embodiment, one or more of the moisturizing component, the skin-soothing component, the anti-wrinkle component, the antibacterial component, and the whitening component can be added according to the requirements, and they are attached to the polymer nanofiber or the pores thereof, and have excellent dispersibility, and the various components can play a synergistic effect.

[0029] Further, the moisturizing component includes at least one of hyaluronic acid, biosaccharide gum; and / or, the toning component includes at least one of menthol, a cooling agent; and / or, the anti-wrinkle component includes at least one of hamamelis virginiana, centella asiatica extract, aloe barbadensis miller extract, vitis vinifera seed extract, a polypeptide, an oligopeptide, retinoic acid; and / or, the antibacterial component includes at least one of vitamin C, a soothing peptide, propolis; and / or, the whitening component includes at least one of niacinamide, arbutin. In an embodiment, the moisturizing component is hyaluronic acid, which is also known as hyaluronan, can carry water and quickly penetrate into the epidermis and dermis, has the biological activity of deep moisturizing, removing free radicals, repairing damaged cells, improving cell activity, soothing, anti-inflammatory, regulating immune function, etc. In an embodiment, the toning component is menthol, which mainly has the effects of stopping itching and pain, calming the skin, and cooling, and can be used to improve symptoms caused by inflammatory lesions or external injuries. In an embodiment, the anti-wrinkle component is a polypeptide, which has the characteristics of inhibiting vesicle release of neurotransmitters, weakening muscle contraction, and reducing wrinkle formation. In an embodiment, the antibacterial component is propolis, which has the effects of moisturizing, promoting tissue regeneration, anti-inflammatory, and pain relief. In an embodiment, the whitening component is arbutin, which can inhibit the activity of tyrosinase in the body, prevent the formation of melanin, reduce skin pigment deposition, and remove freckles and spots, and also has the effects of sterilization and anti-inflammatory

[0030] To solve the above problems, the application further provides a preparation method of the nanofiber hand film, which comprises the following steps: mixing a water-soluble polymer, an efficacy component, and deionized water, stirring to obtain a spinning precursor solution; adding the spinning precursor solution into an electrostatic spinning device for treatment, and then drying to obtain the nanofiber hand film. In an embodiment, different skin care efficacy components are first blended with the water-soluble polymer in a solvent to prepare spinning precursor solutions with different mass concentrations, and then placed in a liquid supply pump, and the nanofiber hand film is prepared by using the electrospinning method. During spinning, water is lost by evaporation, and under the action of an electric field, the spinning solution is pulled into nanoscale solid fibers, thereby weaving a nanofilm with the efficacy component attached to the skin.

[0031] Further, in the step of "mixing a water-soluble polymer, an efficacy component, and deionized water, stirring to obtain a spinning precursor solution", the efficacy component includes at least one of a moisturizing component, a toning component, an anti-wrinkle component, an antibacterial component, and a whitening component. They are attached to the polymer nanofiber or the mesh thereof, and have excellent dispersibility, and the various components can play a synergistic effect.

[0032] Further, the moisturizing ingredient includes at least one of hyaluronic acid, biosaccharide gum; and / or, the toning ingredient includes at least one of menthol, cooling agent; and / or, the anti-wrinkle ingredient includes at least one of Hamamelis virginiana, Centella asiatica extract, Aloe barbadensis Miller (Lavender) extract, Vitis vinifera (grape) seed extract, polypeptide, oligopeptide, retinoic acid; and / or, the antibacterial ingredient includes at least one of vitamin C, soothing peptide, propolis; and / or, the whitening ingredient includes at least one of niacinamide, arbutin. In an embodiment, the kind of efficacy ingredient is added according to the requirement, and the concentration of the added efficacy ingredient does not affect the performance of the electrospun nanofiber.

[0033] Further, in the step of "mixing the water-soluble polymer, the efficacy ingredient and the deionized water, stirring to obtain a spinning precursor solution", the electrospinning device is set at a voltage of 15-18 kV; and / or, the electrospinning device is set at a temperature of 10-45 degrees Celsius; and / or, the electrospinning device is set at an automatic liquid supply speed of 0.5-1 ml / h. In an embodiment, the electrospinning method is set at a spinning voltage of 16 kV, a humidity of 30%, a sliding speed of 0.7 mL / s, an automatic liquid supply speed of 0.7 mL / h, and a temperature of <50°C, to prepare a nanofiber hand film. The electrospinning reaction conditions are matched with the properties of the spinning precursor solution to achieve excellent spinning effect. During electrospinning, the ejection device is filled with charged polymers. Under the action of electric field force and surface tension, the ejection flow is thinned in high-speed oscillation, forming nanoscale fibers. If the humidity is higher than 50%, water will concentrate on the surface of the fibers, thereby affecting the morphology of the nanofiber. If the humidity is too low, the volatile solvent may dry quickly, and the evaporation speed of the solvent may be faster than its removal speed from the needle, thereby causing needle blockage, so that the electrospinning process can only continue for a very short time. The size of the voltage is matched with the mechanical relationship between the electric field force of the jet flow and the solution viscous stress, and together with the sample rate and humidity, it affects the results of electrospinning.

[0034] Example 1:

[0035] PVA with a mass ratio of 10%, propolis with a mass ratio of 15% and hyaluronic acid with a mass ratio of 0.096% were placed in deionized water, heated and stirred at 40°C on a water bath constant temperature magnetic stirrer for 3h to obtain a spinning precursor solution.

[0036] The prepared spinning precursor solution was transferred to a liquid supply pump, and electrospinning was performed under the conditions of a temperature of 30°C and a humidity of 30%, a spinning voltage of 16 kV, a sliding speed of 0.7 mL / s, and an automatic liquid supply speed of 0.7 mL / h. The nanofiber hand film was prepared by drying in a 50°C oven for 2h.

[0037] Example 2:

[0038] Take 10% PVA, 2.9% xylitol and 0.1% acetyl hexapeptide-8 by mass ratio in deionized water, heated and stirred on a water bath constant temperature magnetic stirrer at 40℃ for 3h to obtain the spinning precursor solution.

[0039] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, with a spinning voltage of 15kV, a sliding speed of 0.7mL / s, an automatic liquid supply speed of 0.8mL / h, and drying in an oven at 50℃ for 2h to prepare the nanofiber hand film.

[0040] Example 3:

[0041] Take 10% PVA, 15% nicotinamide and 1% hyaluronic acid by mass ratio in deionized water, heated and stirred on a water bath constant temperature magnetic stirrer at 40℃ for 3h to obtain the spinning precursor solution.

[0042] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, with a spinning voltage of 16kV, a sliding speed of 0.7mL / s, an automatic liquid supply speed of 0.6mL / h, and drying in an oven at 50℃ for 2h to prepare the nanofiber hand film.

[0043] Example 4:

[0044] Take 10% PVA and 3% retinoic acid by mass ratio in deionized water, heated and stirred on a water bath constant temperature magnetic stirrer at 40℃ for 3h to obtain the spinning precursor solution.

[0045] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, with a spinning voltage of 16kV, a sliding speed of 0.7mL / s, an automatic liquid supply speed of 1mL / h, and drying in an oven at 50℃ for 2h to prepare the nanofiber hand film.

[0046] Example 5:

[0047] Take 10% PVA, 15% arbutin and 1% biosugar by mass ratio in deionized water, heated and stirred on a water bath constant temperature magnetic stirrer at 40℃ for 3h to obtain the spinning precursor solution.

[0048] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, with a spinning voltage of 16kV, a sliding speed of 0.7mL / s, an automatic liquid supply speed of 0.6mL / h, and drying in an oven at 50℃ for 2h to prepare the nanofiber hand film.

[0049] Example 6:

[0050] PVA 10% and Hamamelis virginiana 3% were taken in deionized water, heated and stirred for 3h at 40℃ on a water bath constant temperature magnetic stirrer to obtain the spinning precursor solution.

[0051] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, the spinning voltage was 15kV, the sliding speed was 0.7mL / s, the automatic liquid supply speed was 0.7mL / h, and the prepared nanofiber hand film was dried in an oven at 50℃ for 2h.

[0052] Example 7:

[0053] PVA 10% and Centella asiatica extract 3% were taken in deionized water, heated and stirred for 3h at 40℃ on a water bath constant temperature magnetic stirrer to obtain the spinning precursor solution.

[0054] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, the spinning voltage was 17kV, the sliding speed was 0.7mL / s, the automatic liquid supply speed was 0.7mL / h, and the prepared nanofiber hand film was dried in an oven at 50℃ for 2h.

[0055] Example 8:

[0056] PVA 10% and Aloe vera extract 3% were taken in deionized water, heated and stirred for 3h at 40℃ on a water bath constant temperature magnetic stirrer to obtain the spinning precursor solution.

[0057] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 30℃ and humidity 30%, the spinning voltage was 18kV, the sliding speed was 0.7mL / s, the automatic liquid supply speed was 0.8mL / h, and the prepared nanofiber hand film was dried in an oven at 50℃ for 2h.

[0058] Example 9:

[0059] PVA 8%, grape seed extract 3% and hyaluronic acid 1% were taken in deionized water, heated and stirred for 3h at 40℃ on a water bath constant temperature magnetic stirrer to obtain the spinning precursor solution.

[0060] The prepared spinning precursor solution was transferred to the liquid supply pump, and electrospinning was carried out under the conditions of temperature 40℃ and humidity 30%, the spinning voltage was 16kV, the sliding speed was 0.7mL / s, the automatic liquid supply speed was 0.8mL / h, and the prepared nanofiber hand film was dried in an oven at 50℃ for 2h.

[0061] Example 10:

[0062] Take 12% PVA, 3% polypeptide and 1% hyaluronic acid by mass ratio in deionized water, heat and stir on a water bath constant temperature magnetic stirrer at 40°C for 3h to obtain a spinning precursor solution.

[0063] Transfer the prepared spinning precursor solution to a liquid supply pump, and perform electrospinning under the conditions of temperature 45°C and humidity 30%. The spinning voltage is 16kV, the sliding speed is 0.7mL / s, the automatic liquid supply speed is 0.8mL / h, and the prepared nanofiber hand film is dried in an oven at 50°C for 2h.

[0064] Example 11:

[0065] Take 12% PVA, 15% vitamin C and 1% hyaluronic acid by mass ratio in deionized water, heat and stir on a water bath constant temperature magnetic stirrer at 40°C for 3h to obtain a spinning precursor solution.

[0066] Transfer the prepared spinning precursor solution to a liquid supply pump, and perform electrospinning under the conditions of temperature 25°C and humidity 30%. The spinning voltage is 16kV, the sliding speed is 0.7mL / s, the automatic liquid supply speed is 1mL / h, and the prepared nanofiber hand film is dried in an oven at 50°C for 2h.

[0067] Example 12:

[0068] Take 12% PVA, 15% soothing peptide and 1% hyaluronic acid by mass ratio in deionized water, heat and stir on a water bath constant temperature magnetic stirrer at 40°C for 3h to obtain a spinning precursor solution.

[0069] Transfer the prepared spinning precursor solution to a liquid supply pump, and perform electrospinning under the conditions of temperature 25°C and humidity 30%. The spinning voltage is 16kV, the sliding speed is 0.7mL / s, the automatic liquid supply speed is 1mL / h, and the prepared nanofiber hand film is dried in an oven at 50°C for 2h.

[0070] Example 13:

[0071] Take 12% PVA, 3% coolant and 1% biosugar by mass ratio in deionized water, heat and stir on a water bath constant temperature magnetic stirrer at 40°C for 3h to obtain a spinning precursor solution.

[0072] Transfer the prepared spinning precursor solution to a liquid supply pump, and perform electrospinning under the conditions of temperature 35°C and humidity 30%. The spinning voltage is 16kV, the sliding speed is 0.7mL / s, the automatic liquid supply speed is 0.8mL / h, and the prepared nanofiber hand film is dried in an oven at 40°C for 2h.

[0073] Further, the nanofiber hand film of Example 1 is selected for experience, before use, the oil-containing skin care products such as essential oil or emulsion are applied to the hands, then the nanofiber hand film is applied, which can be seen to quickly adhere to the skin, showing transparent gel, and the nanofiber hand film is removed after 6 hours. There is no foreign body and discomfort during the period of applying the fiber film to the hands. Most of the traditional hand film has a complicated use method, which needs to wear gloves to affect daily activities, and the hand film is easily infected with bacteria due to long-term wet essence soaking. It can be seen that, compared with this condition, the nanofiber hand film provided by the embodiment of the present application is dry in normal state, easy to retain the activity of the active ingredient, and appears in a gel state after being activated by essential oil and emulsion, which is long-acting, slow-releasing and skin-adhering, and is more conducive to people to quickly and efficiently skin care in spare time. Moreover, the nanofiber hand film provided by the present application does not add preservatives, and there is no preservative sensitization problem, and it is also more environmentally friendly compared with the traditional skin care film.

[0074] The above is only the preferred embodiment of the present application, and does not limit the patent scope of the present application. For those skilled in the art, the present application can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. within the spirit and principles of the present application shall be included in the patent protection scope of the present application.

Claims

1. A nanofiber hand membrane, characterized in that, include: The nanofiber hand mask contains water-soluble polymers and active ingredients, and reacts with oil compounds to form a gel state upon application. The water-soluble polymer has a nanofiber structure. The water-soluble polymer accounts for 8%-12% of the mass of the nanofiber hand membrane; The water-soluble polymer includes at least one of PVA, PEO, and PVP; The active ingredients include at least one of the following: moisturizing ingredients, toning ingredients, anti-wrinkle ingredients, antibacterial ingredients, and whitening ingredients; The nanofiber hand mask is normally stored as a dry film, but it is activated by essential oils or lotions to become a gel that adheres to the skin.

2. The nanofiber hand membrane as described in claim 1, characterized in that, The moisturizing ingredients include at least one of hyaluronic acid and biosaccharide gum; and / or, The toner ingredient includes at least one of menthol and cooling agents; and / or, The anti-wrinkle ingredients include at least one of North American witch hazel, centella asiatica extract, aloe vera extract, grape seed extract, polypeptides, oligopeptides, and retinoic acid; and / or, The antibacterial ingredient includes at least one of vitamin C, soothing peptides, and propolis; and / or, The whitening ingredients include at least one of niacinamide and arbutin.

3. A method for preparing a nanofiber hand membrane as described in any one of claims 1-2, characterized in that, Includes the following steps: Mix water-soluble polymer, active ingredient and deionized water, stir to obtain spinning precursor solution; The spinning precursor solution is added to an electrospinning device for treatment, and then dried to obtain a nanofiber hand membrane.

4. The method for preparing the nanofiber hand membrane as described in claim 3, characterized in that, In the step of "mixing water-soluble polymer, active ingredient and deionized water, stirring to obtain spinning precursor solution", the active ingredient includes at least one of moisturizing ingredient, skin-toning ingredient, anti-wrinkle ingredient, antibacterial ingredient and whitening ingredient.

5. The method for preparing the nanofiber hand membrane as described in claim 4, characterized in that, The moisturizing ingredients include at least one of hyaluronic acid and biosaccharide gum; and / or, The toner ingredient includes at least one of menthol and cooling agents; and / or, The anti-wrinkle ingredients include at least one of North American witch hazel, centella asiatica extract, aloe vera extract, grape seed extract, polypeptides, oligopeptides, and retinoic acid; and / or, The antibacterial ingredient includes at least one of vitamin C, soothing peptides, and propolis; and / or, The whitening ingredients include at least one of niacinamide and arbutin.

6. The method for preparing the nanofiber hand membrane as described in claim 3, characterized in that, In the step of "mixing water-soluble polymers, active ingredients, and deionized water, stirring, and obtaining a spinning precursor solution", The voltage set for the electrospinning equipment is 15kV-18kV; and / or, The electrospinning equipment is set to a temperature of 10-45 degrees Celsius; and / or, The automatic liquid supply rate of the electrospinning equipment is set to 0.5-1 ml / h.

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