Automatic device for extracting prp by centrifugation

CN116273502BActive Publication Date: 2026-08-18NANJING SHUANGWEI BIOTECH
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Patent Information

Application Number
CN202310336560.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-03-31
Publication Date
2026-08-18
Estimated Expiration
2043-03-31

AI Technical Summary

Technical Problem

[0003]PRP制备分为离心和抽吸两个步骤,其中离心由离心机来完成,而抽吸通常由人工或者半自动设备完成,这使得PRP制备无法完全避免人员操作的影响,存在人工识别PRP位置存在视觉的误差造成提取不准确、提取PRP的浓度及质量不达标、自动化程度低、制备速度慢等问题,也无法实现操作的标准化及流程的规范化

Benefits of technology

1.将制备成分血的离心和抽吸步骤集成到一台设备上,自动化程度高,提取全过程实现无菌化,且具有标准和自定义两种模式供选择,标准模式可一键制备,操作简单,自定义模式工艺参数调节方便;

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Abstract

The application discloses a PRP centrifugal extraction integrated automatic equipment which is composed of consumable components, box body components, upper cover components, centrifugal components, interface adjustment components, pressing plate components and suction components and the like. The application integrates the centrifugal and suction steps of the prepared blood components into one equipment, has high automation degree, and has standard and self-defined two mode selections. In the standard mode, the preparation can be realized by one key, and the operation is simple. In the self-defined mode, the process parameters can be adjusted conveniently. The interface adjustment components identify the position of the blood components to be sucked in the centrifugal tube by using a visual identification device, and adjust the position by adjusting a motor, so that the suction position is ensured to be accurate. The current state of the equipment can be displayed on the control panel, the suction process can be dynamically viewed by a push-pull type perspective cover plate, and the operator can monitor in real time. The box body components are reasonably arranged, the functional components are well combined, and the interference between the components is small.
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Description

Technical Field

[0001] This invention relates to the field of blood separation equipment technology, specifically to an automated PRP centrifugal extraction device. Background Technology

[0002] Since the mid-1990s, PRP has been widely used in various surgical procedures, including cardiac surgery and plastic surgery, and is now also widely used in cosmetic medicine. However, the key to successful PRP procedures lies in the ability to conveniently and quickly extract highly concentrated, high-quality PRP from blood. Currently, PRP is finding excellent clinical applications in medical surgical treatments and bone disease treatments, demonstrating significant therapeutic effects in disease prevention and rehabilitation. It is expected to see widespread clinical application in medical and cosmetic treatments.

[0003] PRP preparation involves two steps: centrifugation and aspiration. Centrifugation is performed by a centrifuge, while aspiration is usually done manually or by semi-automatic equipment. This makes it impossible to completely avoid the influence of human operation in PRP preparation. Problems such as visual errors in manually identifying the PRP location leading to inaccurate extraction, substandard concentration and quality of extracted PRP, low automation, and slow preparation speed cannot be achieved. Furthermore, it is impossible to standardize the operation and regulate the process. Summary of the Invention

[0004] In order to overcome the above-mentioned defects of existing PRP preparation equipment and realize the standardized and regulated preparation of PRP, this invention provides an automated PRP centrifugal extraction device.

[0005] The technical solution adopted in this invention is as follows: A PRP centrifugation extraction integrated automated device, comprising: a consumable assembly including centrifuge tubes, a syringe, and a needle, wherein the syringe and the needle are connected via a conduit; a housing assembly and a top cover assembly; a centrifugation assembly disposed within the housing assembly, having a carrier capable of rotating the centrifuge tubes, wherein the centrifuge tubes remain at a specified angular position after the carrier stops rotating and resets; and an interface adjustment assembly including a visual recognition device, an adjustment motor, and a rotating head, wherein the visual recognition device identifies the position of the blood component to be aspirated within the centrifuge tube, which serves as the adjustment motor's position. A control signal source is provided, and the adjusting motor drives the rotating head to rotate, adjusting the position of the blood component to be aspirated to the optimal aspiration position. The pressure plate assembly includes a pressure plate linear module and a cantilever. The front end of the cantilever has a locking slot, and the needle is equipped with an integrated locking plate. The locking plate is installed in the locking slot, and the needle moves downwards with the locking plate under the drive of the pressure plate linear module, inserting into the central liquid collection tube of the centrifuge tube. The aspiration assembly includes an aspiration linear module and a piston slider. The syringe is fixed inside the aspiration assembly, and the piston of the syringe is installed on the piston slider, moving under the drive of the aspiration linear module.

[0006] Preferably, the centrifuge tube includes an outer tube body and a bottom cover. The bottom end of the outer tube body is open and is movably engaged with the bottom cover through a threaded pair. The rotating head drives the bottom cover to rotate.

[0007] Preferably, the housing assembly is divided into a centrifugal chamber, a suction chamber, and an electrical chamber. The centrifugal assembly, the interface adjustment assembly, and the pressure plate assembly are disposed in the centrifugal chamber, the suction assembly is disposed in the suction chamber, and the electrical chamber is used to house electrical components.

[0008] Preferably, the inner side of the cover assembly is equipped with a supplementary light for the visual recognition device.

[0009] Preferably, the centrifugal assembly further includes a support, a centrifugal motor, and a main shaft. The centrifugal motor is mounted on the support and drives the main shaft to rotate. The carrier is mounted on the upper end of the main shaft.

[0010] Preferably, a retaining ring is installed at the outer end of the carrier, and a matching tube is installed in the retaining ring. The centrifuge tube is installed in the matching tube, and the matching tube has a through-and-through structure.

[0011] Preferably, a second carrier is used to replace the carrier. The second carrier has a first retaining ring and a second retaining ring installed at both ends. The first retaining ring and the second retaining ring are each equipped with a first adapter tube and a second adapter tube. The first retaining ring has a first mating part, and the first adapter tube has a corresponding second mating part. After the first mating part and the second mating part are mated, the first retaining ring and the first adapter tube are assembled in place.

[0012] Preferably, the interface adjustment component further includes an adjustment line module and an adjustment member. The rotating head and the adjustment member move up and down with the adjustment line module. The adjustment member is located outside the rotating head and is positioned higher than the rotating head. After the adjustment member cooperates with the adapter tube, it adjusts the angle of the lower end of the adapter tube.

[0013] Preferably, the visual recognition device is a high-definition camera module, which faces the window at the throat of the centrifuge tube. The adjusting motor adjusts the position of the blood component to be aspirated to 0.5-3mm below the liquid collection port of the central liquid collection tube inside the centrifuge tube based on the signal from the high-definition camera module.

[0014] Preferably, the aspiration assembly further includes a syringe limiting groove and a catheter fixing groove, wherein the syringe is placed in the syringe limiting groove and the catheter is placed in the catheter fixing groove.

[0015] The present invention has the following beneficial effects: 1. The centrifugation and aspiration steps for preparing blood components are integrated into one device, which is highly automated and achieves aseptic extraction throughout the entire process. It also offers two modes: standard and custom. The standard mode can prepare blood components with one click and is easy to operate, while the custom mode allows for convenient adjustment of process parameters. 2. The position of the blood component to be aspirated inside the centrifuge tube is identified by a visual recognition device, and the motor and linear module are adjusted accordingly to ensure the accuracy of the aspiration position, thereby improving the recovery rate and concentration rate of the blood component to be aspirated. 3. The centrifugation status and process parameters can be displayed on the control panel and interacted with by the human-machine interface. The suction process can be dynamically viewed through the push-pull transparent cover, which is convenient for the operator to monitor in real time. 4. The enclosure space is reasonably arranged, the functional components are well integrated, and there is little interference between them. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the consumable components in an embodiment of the present invention.

[0017] Figure 2 This is a schematic diagram of the external shape of an embodiment of the present invention.

[0018] Figure 3 This is a schematic diagram showing the positions of each compartment of the enclosure assembly in an embodiment of the present invention (the side cover of the top cover assembly and the electrical compartment are omitted).

[0019] Figure 4 This is a schematic diagram of the upper cover assembly in an embodiment of the present invention.

[0020] Figure 5 This is a schematic diagram showing the installation of each functional component in an embodiment of the present invention.

[0021] Figure 6 This is a schematic diagram of the centrifuge assembly in an embodiment of the present invention.

[0022] Figure 7 This is a schematic diagram of the centrifugal assembly in a second embodiment of the present invention.

[0023] Figure 8 This is a schematic diagram of the interface adjustment component in an embodiment of the present invention.

[0024] Figure 9 This is a schematic diagram of the pressure plate assembly in an embodiment of the present invention.

[0025] Figure 10 This is a schematic diagram of the suction component in an embodiment of the present invention.

[0026] Figure 11 This is a schematic diagram of the automatic image recognition interface of the visual recognition device in an embodiment of the present invention.

[0027] Consumables assembly 1, centrifuge tube 101, syringe 102, needle 103, tubing 104, outer tube body 105, bottom cover 106, clamping plate 107; Box assembly 2, centrifuge chamber 201, suction chamber 202, electrical chamber 203, transparent cover 204, control panel 205, maintenance side panel 206; Top cover assembly 3, supplementary light 301, buffer support rod 302, hinge 303; Centrifugal assembly 4, carrier 401, second carrier 401a, support 402, centrifugal motor 403, main shaft 404, retaining ring 405, first retaining ring 405a, second retaining ring 405b, adapter tube 406, first adapter tube 406a, second adapter tube 406b, protrusion 407, notch 408; Interface adjustment component 5, visual recognition device 501, adjustment motor 502, rotating head 503, adjustment linear module 504, adjustment component 505; Pressure plate assembly 6, pressure plate linear module 601, cantilever 602, bayonet 603; Suction assembly 7, suction linear module 701, piston slider 702, syringe limiting groove 703, and catheter fixing groove 704. Detailed Implementation

[0028] The present invention will be further described below with reference to the embodiments and accompanying drawings.

[0029] In the embodiments, such as Figures 1-10The diagram shows an automated PRP centrifugation extraction device, comprising: a consumable assembly 1, including a centrifuge tube 101, a syringe 102, and a needle 103, the syringe 102 and the needle 103 being connected via a conduit 104; a housing assembly 2 and a top cover assembly 3; a centrifugation assembly 4, disposed within the housing assembly 2, having a carrier 401 capable of rotating the centrifuge tube 101, the centrifuge tube 101 remaining at a specified angle position after the carrier 401 stops rotating and resets; and an interface adjustment assembly 5, including a visual recognition device 501, an adjustment motor 502, and a rotating head 503, the visual recognition device 501 identifying the position of the blood component to be extracted within the centrifuge tube 101, serving as the control signal source for the adjustment motor 502, which drives the rotating head 503 to rotate, thus adjusting the position of the blood component to be extracted. The position of the blood component is adjusted to the optimal aspiration position. Generally, the visual recognition device 5 mainly identifies the position of the red blood cell and PRP interface (i.e., the PRP position) within the centrifuge tube 101. The pressure plate assembly 6 includes a pressure plate linear module 601 and a cantilever 602. The front end of the cantilever 602 has a locking slot 603. The needle 103 is equipped with an integrated locking plate 107, which is installed in the locking slot 603. The needle 103 moves downward with the locking plate 107 under the drive of the pressure plate linear module 601 and is inserted into the central liquid collection tube of the centrifuge tube 101. The aspiration assembly 7 includes an aspiration linear module 701 and a piston slider 702. The syringe 102 is fixed in the aspiration assembly 7, and the piston of the syringe 102 is installed on the piston slider 702 and moves under the drive of the aspiration linear module 701. This embodiment integrates the centrifugation and aspiration steps of preparing blood components into one device, with a high degree of overall automation. The equipment offers two modes: standard and custom. The standard mode allows for one-click preparation and is easy to operate, while the custom mode offers the advantage of convenient parameter adjustment.

[0030] In the embodiments, such as Figure 1 As shown, the centrifuge tube 101 includes an outer tube body 105 and a bottom cover 106. The bottom end of the outer tube body 105 is open and is movably engaged with the bottom cover 106 via a threaded pair. The rotating head 503 drives the bottom cover 106 to rotate. Specifically, the outer tube body 105 is divided into an upper chamber and a lower chamber, which are connected as one unit through a throat chamber. A central liquid extraction tube is built into the outer tube body. The lower end of the central liquid extraction tube is the liquid extraction port, which is located inside the throat chamber. The upper end of the central liquid extraction tube is welded or glued to the top wall of the upper chamber and is connected to the suction port on the top wall. The structure of the centrifuge tube 101 in this embodiment has been disclosed in patent documents CN216678283U, CN216677078U, and CN307626006S, and the principle of each centrifuge tube is basically the same.

[0031] In the embodiments, such as Figure 2 , 3As shown, the housing assembly 2 is divided into a centrifugal chamber 201, a suction chamber 202, and an electrical chamber 203. The centrifugal assembly 4, the interface adjustment assembly 5, and the pressure plate assembly 6 are housed within the centrifugal chamber 201. The suction assembly 7 is housed within the suction chamber 202. The electrical chamber 203 houses electrical mounting plates, the PLC main control board, power supplies, and other electrical components. The electrical chamber 203 is equipped with a detachable maintenance side panel 206. Specifically, the centrifugal chamber 201 is located on the left, while the suction chamber 202 and the electrical chamber 203 are located on the right, with the suction chamber 202 positioned above the electrical chamber 203. This configuration of the housing assembly 2 provides a reasonable spatial arrangement, good integration between functional components, and minimal interference between them. In addition, a sliding transparent cover 204 is installed above the suction chamber 202, and an operation panel 205 is installed above the electrical chamber 203. Therefore, during equipment operation, the centrifugation status and process parameters can be displayed on the control panel 205, showing the current status of the equipment in real time, including centrifugation, adjustment, and suction. This human-machine integration allows operators to easily observe the current status of the equipment. Furthermore, the dynamic process of PRP suction can also be dynamically viewed through the sliding transparent cover 204, facilitating real-time monitoring by the operator.

[0032] In the embodiments, such as Figure 4 As shown, the top cover assembly 3 is mounted and connected to the housing assembly 2 via a hinge 303. A buffer support rod 302 is also provided between the top cover assembly 3 and the housing assembly 2. Inside the top cover assembly 3 is a visual recognition device 501 equipped with a supplementary light 301. The supplementary light 301 is an LED light strip, designed to automatically illuminate after centrifugation to improve the accuracy of identifying the PRP suction position.

[0033] In the embodiments, such as Figure 5 , 6As shown, the centrifuge assembly 4 also includes a support 402, a centrifuge motor 403, and a main shaft 404. The centrifuge motor 403 is mounted on the support 402 and drives the main shaft 404 to rotate. The carrier frame 401 is mounted on the upper end of the main shaft 404. A retaining ring 405 is installed on the outer end of the carrier frame 401, and a matching tube 406 is installed in the retaining ring 405. The centrifuge tube 101 is installed in the matching tube 406, which has a through-hole structure. During operation, the retaining ring 405 is first installed in the carrier frame 401, the centrifuge tube 101 is installed in the matching tube 406, and then the centrifuge tube 101 and the matching tube 406 are installed together in the retaining ring 405. The centrifuge assembly 4 in this embodiment has the following characteristics: (1) The centrifuge motor 403 is a servo motor, which is reliable and stable, avoiding the centrifugation effect caused by unstable speed, and the process parameters are easy to adjust; (2) When the carrier 401 stops rotating, the centrifuge motor 403, under the control of the servo driver, makes the carrier 401 reset to the specified angle position after the rotation stops, so that the centrifuge tube 101 containing blood stays at the specified suction position, aligning with the interface adjustment assembly 5 and the pressure plate assembly 6, so as to facilitate subsequent interface adjustment and automatic suction; (3) The lower end of the adapter tube 406 is a through structure, which facilitates the interface adjustment assembly 5 to contact the centrifuge tube 101, so as to facilitate adjusting the interface position of the blood to be suctioned to the optimal position.

[0034] In another embodiment, such as Figure 7As shown, this is a centrifuge assembly 4 with a different structure. A second carrier 401a replaces the original carrier 401. The second carrier 401a only houses two centrifuge tubes 101. A first retaining ring 405a and a second retaining ring 405b are respectively installed at both ends of the second carrier 401a. A first adapter tube 406a and a second adapter tube 406b are installed in each of the first and second retaining rings 405a and 405b, respectively. The first retaining ring 405a has a first mating part, and the first adapter tube 406a has a corresponding second mating part. After the first and second mating parts are engaged, the first retaining ring 405a and the first adapter tube 406a are assembled in place. The first mating part is located on the upper surface of the first retaining ring 405a and is a protrusion 407 with a width and height. The second mating part is located on the outer support ring of the first adapter tube 406a and is a notch 408 with a corresponding width and height. During operation, centrifuge tube 101 (blood) is first placed in the designated first adapter tube 406a, and then assembled into the corresponding first retaining ring 405a; while centrifuge tube 101 (pure water) is first placed in the second adapter tube 406b, and then assembled into the corresponding second retaining ring 405b. During this process, the mutual positioning of the first mating part 407 and the second mating part 408 ensures that the first adapter tube 406a can only be assembled into the first retaining ring 405a. Based on this, the centrifuge motor 403 stops and resets, causing the carrier 1 to stop at the designated angle position, so that the centrifuge tube 101 (blood) can remain at the designated aspiration position after centrifugation. This facilitates a one-stop, closed, aseptic, automated extraction function, including centrifugation, positioning, puncture, adjustment of liquid level, control of extraction speed, and precise extraction volume. It should be noted that the centrifuge tube 101 containing blood does not necessarily have to be placed in the first adapter tube 406a; rather, one of the first adapter tube 406a and the second adapter tube 406b needs to be designated and kept unchanged. In addition, the first retaining ring 405a and the second retaining ring 405b are assembled on the second carrier 401a and cannot be removed, in order to avoid incorrect installation of the centrifuge tube 101.

[0035] In the embodiments, such as Figure 5 , 8As shown, the interface adjustment component 5 also includes an adjustment linear module 504 and an adjustment element 505. The rotating head 503 and the adjustment element 505 rise and fall with the adjustment linear module 504. The adjustment element 505 is located outside the rotating head 503 and is positioned higher than the rotating head 503. After the adjustment element 505 cooperates with the adapter tube 406, it adjusts the angle of the lower end of the adapter tube 406. In this embodiment, the visual recognition device 501 is a high-definition camera module, and the adjustment motor 502 is a stepper motor. The high-definition camera module faces the viewing window at the throat chamber of the centrifuge tube 101 to identify the position of the blood component to be aspirated. Based on the signal from the high-definition camera module, the adjustment motor 502 adjusts the position of the blood component to be aspirated to 0.5~3mm below the liquid collection port of the central liquid collection tube inside the centrifuge tube 101 to ensure accurate aspiration position. The adjustment linear module 504 is used to adjust the height of the rotating head 503 and the adjustment element 505 to facilitate cooperation with the centrifuge tube 101. The adjusting component 505 is fitted onto the lower end of the adapter sleeve 406 in the form of an outer sleeve, or inserted into the through hole at the lower end of the adapter sleeve 406 in the form of a plug, or clamped onto the outside of the adapter sleeve 406 with clamps, in order to correct the angle of the adapter sleeve 406 and ensure that the adapter sleeve 406 is in a vertical position.

[0036] In the embodiments, such as Figure 5 , 9 As shown, the cantilever 602 of the pressure plate assembly 6 has a locking slot 603 at its front end, and the needle 103 is equipped with an integrated locking plate 107, which is installed in the locking slot 603. In this embodiment, the locking slot 603 facilitates the insertion and removal of the locking plate 107, making operation convenient. After the cantilever 602 moves down, it actually has two functions: first, it allows the needle 103 to pierce into the central liquid collection tube of the centrifuge tube 101; second, it acts as a pressure plate for the centrifuge tube 101, playing a positioning and fixing role to prevent the centrifuge tube 101 from shaking. This facilitates the interface adjustment assembly 5 to adjust the position of the blood component to be aspirated, so that the position of the blood component to be aspirated can be accurately calibrated to the aspiration position, ensuring the accuracy of the aspiration position.

[0037] In the embodiments, such as Figure 5 , 10 As shown, the aspiration assembly 7 also includes a syringe limiting groove 703 and a catheter fixing groove 704. The syringe 102 is placed in the syringe limiting groove 703, and the catheter 104 is placed in the catheter fixing groove 704. In this embodiment, the syringe 102 and the catheter 104 are positioned by the syringe limiting groove 703 and the catheter fixing groove 704, respectively, to facilitate the automatic and precise aspiration of PRP by the aspiration linear module 701.

[0038] The operation steps for preparing PRP using the automated PRP centrifugation extraction device in this embodiment are as follows: Step 1, Preparations before centrifugation: 1.1. Open the consumable assembly 1 set, take out the centrifuge tube 101, and at the same time take out the multi-functional aspiration assembly (composed of syringe 102, needle 103, tubing 104 and clamping plate 107). 1.2. Inject whole blood and purified water into the corresponding centrifuge tubes 101 respectively, and then weigh and balance them by adding or subtracting purified water to make the two equal in weight; 1.3. Place the balanced centrifuge tubes 101 into their corresponding matching tubes 406 in the centrifuge assembly 4. Then, place the other components of the consumable assembly 1 into their corresponding positions in the equipment. Specifically, insert the clamping plate 107 into the clamping slot 603, insert the syringe 102 into the syringe limiting groove 703, and insert the tubing 104 into the tubing fixing groove 704.

[0039] Step 2, automatic centrifugation of whole blood: 3.1. Close and lock the top cover assembly 3. On the control panel 205, select the standard mode or the custom mode (centrifugation parameters such as speed, time, and PRP suction volume can be set) and then click the "Start" button. 3.2. The centrifuge assembly 4 operates automatically. After centrifugation is completed, the centrifuge motor 403, under the control of the servo driver, resets the carrier 401 to the specified angle position after rotation stops, so that the centrifuge tube 101 containing blood stays at the specified suction position, and the supplementary light 301 on the top cover assembly 3 is automatically lit.

[0040] Step 3, automatic adjustment of suction position: 3.1. The cantilever 602 of the pressure plate assembly 6 moves downward under the drive of the pressure plate linear module 601, pressing the centrifuge tube 101 onto the appropriate matching tube 406 and retaining ring 405, while simultaneously inserting the needle 103 into the central liquid collection tube of the centrifuge tube 101. 3.2. The adjustment linear module 504 of the interface adjustment component 5 drives the adjustment motor 502, the rotating head 503 and the adjustment component 505 to rise synchronously. The adjustment component 505 first contacts the matching tube 406 to adjust and fix the lower end of the matching tube 406. Then the rotating head 503 contacts the bottom cover 106 of the centrifuge tube 101 and fixes the rotating head 503 and the bottom cover 106 circumferentially. 3.3. The visual recognition device 501 starts working. First, it captures images of the centrifuge tube 101 after centrifugation and the blood inside. Then, it uses an automatic image recognition algorithm (such as an image binarization algorithm) to accurately identify the PRP location (the interface between the white membrane layer and the red blood cells). Figure 11 (At the crosshair cursor position), the adjusting motor 502 drives the rotating head 503 to rotate (the adjusting linear module 504 synchronously drives the adjusting motor 3 to rise), so that the PRP position inside the centrifuge tube 1 is adjusted upward until the PRP position is 0.5~3mm below the liquid inlet of the central liquid inlet tube inside the centrifuge tube 1, thus completing the interface adjustment work.

[0041] Step 4, PRP automatic aspiration: The suction linear module 701 of the suction assembly 7 drives the piston of the syringe 102 to slide outward. The suction volume is precisely controlled by the suction linear module 701, and the suction action is completed accurately and efficiently. During the suction process, the dynamic process of PRP suction can be dynamically viewed by the push-pull transparent cover 204.

[0042] Step 5, PRP preparation is complete: After the device emits a completion prompt beep, click the "End" button on the control panel 205 to open the top cover assembly 3, remove all consumable parts, and the entire operation is complete; click the "Reset" button on the panel 205 to reset all functional components, and you can proceed with the next operation.

[0043] After preparation, the PRP prepared in this embodiment was tested using a hematology analyzer to measure its platelet concentration and verify the effectiveness and performance of the equipment. The results are shown in the table below:

[0044] The three groups of samples in the table (1#, 2#, and 3#) came from the same blood sample. The average platelet concentration is the average of the platelet concentrations obtained from three tests of each PRP sample group. Competitor 1 and Competitor 2 are PRPs prepared using equipment provided by two well-known domestic manufacturers.

[0045] As shown in the table above: (1) The platelet recovery rate of the PRP prepared by the equipment in this embodiment is 63.9%~79.4% relative to the platelet concentration rate in the original whole blood, and the platelet concentration rate of the PRP is 5.35~6.51 times that in the original whole blood; (2) The platelet recovery rate of the PRP prepared by similar equipment in China is 51%~69%, and the platelet concentration rate is 4~6 times. The equipment in this embodiment has obvious advantages.

[0046] Obviously, the above embodiments of the present invention are merely illustrative examples to illustrate the invention and are not intended to limit the implementation of the invention. Other obvious variations or modifications derived from the essential spirit of the invention still fall within the protection scope of the invention.

Claims

1. An automated PRP centrifugal extraction device, characterized in that, include: The consumable assembly (1) includes a centrifuge tube (101), a syringe (102) and a needle (103), wherein the syringe (102) and the needle (103) are connected by a conduit (104); Box assembly (2) and top cover assembly (3); The centrifuge assembly (4) is located inside the box assembly (2) and has a carrier (401) that can drive the centrifuge tube (101) to rotate. After the carrier (401) stops rotating and resets, the centrifuge tube (101) stays at a specified angle position. The interface adjustment component (5) includes a visual recognition device (501), an adjustment motor (502), and a rotating head (503). The visual recognition device (501) identifies the position of the blood component to be aspirated in the centrifuge tube (101) and serves as the control signal source for the adjustment motor (502). The adjustment motor (502) drives the rotating head (503) to rotate so that the position of the blood component to be aspirated is adjusted to the optimal aspiration position. The pressure plate assembly (6) includes a pressure plate linear module (601) and a cantilever (602). The front end of the cantilever (602) is provided with a slot (603). The needle (103) is equipped with an integrated clamping plate (107). The clamping plate (107) is installed in the slot (603). The needle (103) moves down with the clamping plate (107) driven by the pressure plate linear module (601) and is inserted into the central liquid collection tube of the centrifuge tube (101). The suction assembly (7) includes a suction linear module (701) and a piston slider (702). The syringe (102) is fixed inside the suction assembly (7). The piston of the syringe (102) is mounted on the piston slider (702) and moves under the drive of the suction linear module (701). The centrifuge tube (101) includes an outer tube body (105) and a bottom cover (106). The bottom end of the outer tube body (105) is open and is movably engaged with the bottom cover (106) through a threaded pair. The rotating head (503) drives the bottom cover (106) to rotate. A retaining ring (405) is installed at the outer end of the carrier (401), and a matching tube (406) is installed in the retaining ring (405). The centrifuge tube (101) is installed in the matching tube (406), and the matching tube (406) has a through-hole structure.

2. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The housing assembly (2) is divided into a centrifugal chamber (201), a suction chamber (202) and an electrical chamber (203). The centrifugal assembly (4), the interface adjustment assembly (5) and the pressure plate assembly (6) are located in the centrifugal chamber (201). The suction assembly (7) is located in the suction chamber (202). The electrical chamber (203) is used to place electrical components.

3. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The inner side of the cover assembly (3) is equipped with a supplementary light (301) for the visual recognition device (501).

4. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The centrifugal assembly (4) also includes a bracket (402), a centrifugal motor (403) and a main shaft (404). The centrifugal motor (403) is mounted on the bracket (402) and drives the main shaft (404) to rotate. The carrier (401) is mounted on the upper end of the main shaft (404).

5. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, A second carrier (401a) is used to replace the carrier (401). The second carrier (401a) has a first retaining ring (405a) and a second retaining ring (405b) installed at both ends. The first retaining ring (405a) and the second retaining ring (405b) are each equipped with a first adapter tube (406a) and a second adapter tube (406b). The first retaining ring (405a) is provided with a first mating part, and the first adapter tube (406a) is provided with a corresponding second mating part. After the first mating part and the second mating part are mated, the first retaining ring (405a) and the first adapter tube (406a) are assembled in place.

6. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The interface adjustment component (5) further includes an adjustment linear module (504) and an adjustment component (505). The rotating head (503) and the adjustment component (505) move up and down with the adjustment linear module (504). The adjustment component (505) is located outside the rotating head (503) and is positioned higher than the rotating head (503). After the adjustment component (505) cooperates with the adapter tube (406), it adjusts the angle of the lower end of the adapter tube (406).

7. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The visual recognition device (501) is a high-definition camera module. The high-definition camera module faces the viewing window at the throat chamber of the centrifuge tube (101). The adjustment motor (502) adjusts the position of the blood component to be aspirated to 0.5~3mm below the liquid collection port of the central liquid collection tube inside the centrifuge tube (101) based on the signal from the high-definition camera module.

8. The PRP centrifugal extraction integrated automated equipment according to claim 1, characterized in that, The suction assembly (7) further includes a syringe limiting groove (703) and a catheter fixing groove (704), wherein the syringe (102) is placed in the syringe limiting groove (703) and the catheter (104) is placed in the catheter fixing groove (704).

Citation Information

Patent Citations

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    CN216677078U

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