Wound dressing with encapsulated medicament

By designing a wound dressing that also encapsulates medication, and using a self-sealing container to encapsulate powdered drugs, the problem of uneven drug application in existing dressings is solved, resulting in better hemostasis, analgesia, and antibacterial effects, and simplifying the operation process.

CN116327485BActive Publication Date: 2026-03-24THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-03-21
Publication Date
2026-03-24

AI Technical Summary

Technical Problem

When existing dressings are used, problems such as uneven application and spillage of additional functional ingredients, such as hemostatic agents, can affect the therapeutic effect. Furthermore, the manufacturing process is complex and the functions are limited.

Method used

A wound dressing with drug encapsulation function is designed, including a sheet-like adhesive part and a double-layered cystic drug-carrying part. Powdered drugs are encapsulated through a self-sealing sac. The side of the drug-carrying part near the release film is flush with the adhesive side of the adhesive part. It is simple to operate and can flexibly combine encapsulation drugs.

Benefits of technology

It achieves uniform drug application and enhances hemostatic, analgesic, and antibacterial effects, improves the flexibility and reliability of treatment outcomes, and simplifies the operation process.

✦ Generated by Eureka AI based on patent content.

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    Figure CN116327485B_ABST
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Abstract

The application provides a wound dressing with a packaging agent function, one side of a sticking part is a sticking surface, the other side of the sticking part is a water isolation surface, a release film is arranged on the sticking surface, a double-layer capsule structure is arranged in the middle of the sticking part, a convex end of the double-layer capsule structure is away from the side of the release film, and the double-layer capsule structure is a drug loading part; the drug loading part comprises a self-sealing container, the self-sealing container is away from the convex end, the self-sealing container seals the convex structure, powder-shaped drug components with a wound treatment function can be filled into the drug loading part through the self-sealing container, and the drug components are packaged; the surface of the drug loading part close to the release film is flush with the sticking surface of the sticking part. When functional components such as additional hemostasis are needed, the application adopts the self-sealing container to seal the added components, the structure is simple, the packaging agent can be flexibly combined, the operation is convenient, and the technical defects of uneven application on the surface of a wound, external scattering and other factors affecting the treatment effect caused by additional packaging are solved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a wound dressing with a function of packaging medicaments. BACKGROUND

[0002] In medical activities, when the wound caused by trauma, injury and other reasons bleeds, the emergency treatment usually needs to use a dressing to cover the bleeding wound. This operation can bring the following effects: 1. The wound is closed, which reduces blood spillage and wound contamination by isolating the wound from the external environment; 2. Absorb the bleeding and exudate of the wound, keep the wound relatively clean, and facilitate wound recovery; 3. When further external pressure is needed, it provides some protection to the wound; 4. When the dressing contacts the wound, it contacts the blood to promote blood clotting and enhance the hemostatic effect of the wound. The dressing used in clinical practice also increases the functions of hemostasis, anti-inflammatory and analgesia by adding special drugs on the surface or modifying the process. However, the existing dressing has the following technical defects in the use process: 1. Special drugs and materials need to be attached to the surface of the dressing in advance through a special process. The process is complex and the attached components are limited. The achieved hemostatic effect is also limited. The function needs to be pre-set; 2. If additional functional components such as hemostatic powder are added to the wound, the added components will be unevenly applied to the surface of the wound and will be scattered, which will affect the treatment effect.

[0003] Therefore, how to improve the treatment effect when dealing with heavy bleeding or adding additional components to the wound has become a pressing problem. Clinically, a covering and filling type wound dressing with a function of packaging medicaments is needed, which can not only cover, fill and compress according to the normal function, but also can easily package medicaments to increase the functions of hemostasis, analgesia and antibiosis. SUMMARY

[0004] In view of the problems in the prior art, the present application provides a wound dressing with a function of packaging medicaments to solve at least one of the above technical problems.

[0005] The technical scheme of the present application is: a wound dressing with a function of packaging medicaments, comprising a paste part of a sheet structure, one side of the paste part is a paste surface, the other side of the paste part is a water-proof surface, a release film is arranged on the paste surface, a double-layer capsule structure is arranged in the middle of the paste part, the convex end of the double-layer capsule structure is away from the side of the release film, and the double-layer capsule structure is a drug loading part; the drug loading part comprises a self-sealing container, the self-sealing container is away from the convex end, the self-sealing container closes the convex structure, and the self-sealing container can fill and package powder-shaped medicaments with wound treatment function into the drug loading part; the surface of the drug loading part close to the release film is flush with the paste surface of the paste part.

[0006] The present application is aimed at the functional components such as large hemorrhage or additional addition of other hemostatic components, such as the addition of hemostatic powder at the wound, the self-sealing container mouth is used to close the added components, the structure is simple, the drug-loaded part can be combined and packaged flexibly, the operation is convenient, the face of the drug-loaded part close to the release film is flush with the sticking face of the sticking part, which is beneficial to the placement of the drug-loaded part on the skin and the sticking of the sticking face on the skin around the wound, and solves the technical defects of uneven application on the wound surface, external scattering and other influences on the treatment effect caused by additional packaging, and the self-sealing container mouth can package the drug to increase the functions of hemostasis, analgesia, antibiosis and the like.

[0007] Preferably, the release film comprises a release film inner sheet and a release film outer sheet located at the outer circle of the release film inner sheet. The release film outer sheet comprises two symmetrically arranged sheet structures, the two sheet structures are located at the two ends of the release film inner sheet, and the two sheet structures are both provided with a circular arc opening, and the openings of the two sheet structures are both directed to the release film inner sheet.

[0008] The release film of the present application is in conformity with the sticking part in shape and size, and the release film is attached to the sticking face of the sticking part in the standby state, so that the adhesion of the sticking face can be maintained in the unused state; the release film is designed as a release film inner sheet and a release film outer sheet based on the boundary of the drug-loaded part, the release film inner sheet is slightly smaller than the specification of the drug-loaded part, and the remaining part forms the release film outer sheet, which can be individually or entirely removed from the sticking face of the sticking part according to the requirements. BRIEF DESCRIPTION OF DRAWINGS

[0009] Figure 1 It is a longitudinal sectional view of the functional drug dressing pre-packaged by the drug-loaded part of the present application.

[0010] Figure 2 It is a bottom view of Figure 1 .

[0011] Figure 3 It is a longitudinal sectional view of the functional drug dressing to be packaged by the drug-loaded part of the present application.

[0012] Figure 4 It is a bottom view of Figure 3 .

[0013] Figure 5 It is a top view of the release film of the present application.

[0014] In the figure: 1. Sticking part; 101. Water-proof surface; 102. Sticking face; 2. Drug-loaded part; 201. Outer layer of drug-loaded part; 202. Inner layer of drug-loaded part; 203. Drug-loaded part container mouth; 3. Release film; 301. Release film inner sheet; 302. Release film outer sheet. DETAILED DESCRIPTION

[0015] The present application will be further described below in combination with the drawings.

[0016] ReferenceFigures 1-5 The structures, proportions, sizes, etc. shown in the drawings accompanying the present specification are merely intended to facilitate the understanding of the content disclosed herein by those skilled in the art, and are not intended to limit the conditions under which the present application can be implemented, and therefore do not have technical significance. Any modification of the structure, change of the proportion relationship, or adjustment of the size, without affecting the effects that can be achieved by the present application, should still fall within the scope of the technology disclosed by the present application. Meanwhile, the terms such as "upper", "lower", "left", "right", "middle", and "one" used in the present specification are merely for the convenience of clear description, and are not intended to limit the scope of the present application, and the change or adjustment of the relative relationship, without substantially changing the technical content, is also considered as the scope of the present application.

[0017] Embodiment one, a wound dressing with packaging agent function, referring to Figure 3 The dressing is composed of a sticking part 1, a drug loading part 2, and a release film 3. The sticking part 1 is in a sheet structure, which can have different shapes and sizes, and can be rectangular, square, circular, oval, etc. that are beneficial to covering the target wound. When the sticking part 1 adopts a rectangular sheet structure, the size is 15 cm long and 10 cm wide. One side of the sticking part 1 is a sticky side 102 with a function of sticking to the skin. The other side of the sticking part 1 is a water-resistant side 101 without stickiness, which has water-resistant and breathable properties. The water-resistant side 101 is provided with a release film 3. The middle part of the sticking part 1 is provided with a double-layer capsule structure, which is circular or oval. When the double-layer capsule structure adopts an oval shape, the size is 8 cm in long diameter and 4 cm in short diameter. The convex end of the double-layer capsule structure is away from the side of the release film 3. The double-layer capsule structure is the drug loading part 2. The sticking part 1 is slightly concave in the direction of the water-resistant side 101 at the position of the drug loading part 2, forming a spoon shape, and the deepest part is 2 cm. The drug loading part 2 includes a self-sealing container. The self-sealing container is away from the convex end, and the self-sealing container seals the convex structure. Through the self-sealing container, powder-shaped drug components with wound treatment function can be filled and packaged into the drug loading part 2. The side of the drug loading part 2 close to the release film 3 is flush with the sticky side 102 of the sticking part 1. The present application adopts a self-sealing container to seal the added components when additional functional components such as hemostatic powder are added to the wound, which has a simple structure and can flexibly combine and package the agents. The operation is convenient. The side of the drug loading part close to the release film is flush with the sticky side of the sticking part, which is beneficial to the placement of the drug loading part on the skin and the sticking of the sticky side to the skin around the wound. It solves the technical defects that affect the treatment effect due to uneven application on the surface of the wound and external scattering caused by additional packaging. The self-sealing container can conveniently package the agents to increase the functions of hemostasis, analgesia, and antibiosis.

[0018] Embodiment two, based on embodiment one, referring toFigure 4 The self-sealing containing port comprises a drug-loading portion outer layer 201 and a drug-loading portion inner layer 202, wherein the drug-loading portion inner layer 202 is close to one side of the release film 3, the drug-loading portion outer layer 201 is away from the other side of the release film 3, and a drug-loading portion containing port 203 is arranged between the drug-loading portion outer layer 201 and the drug-loading portion inner layer 202. The self-sealing containing port of the present application adopts a sheet structure that overlaps each other, with a smaller semi-elliptical sheet of the drug-loading portion inner layer on the outside and a larger semi-elliptical sheet of the drug-loading portion outer layer on the inside, forming an ellipse with a major axis of 8 cm and a minor axis of 4 cm, and an overlapping part of 1 cm, which is beneficial to the overlapping part to have a good encapsulation effect on the internal encapsulated medicament in a normal state, and is beneficial to injecting extra medicament into the capsular structure of the drug-loading portion.

[0019] Example Three, based on Example Two, the drug-loading portion outer layer 201 is any one of a medical single-layer gauze, a modified gauze made by special process, or a drug-containing gauze, and the coating layer can be more than one layer. The present application adopts a medical single-layer gauze, and the sparse grid structure thereof can allow powdery substances to leak through, but the stable structure of the drug-loading portion inner layer ensures that the internal encapsulated powdery medicament will not easily overflow.

[0020] Example Four, based on Example Three, the drug-loading portion inner layer 202 adopts any one of starch-PVA, PVA, starch and vegetable oil, or water-soluble gauze, which can quickly dissolve in water, and the drug-loading portion inner layer 202 can contain powdery drugs. The drug-loading portion inner layer of the present application is made of a material that can contain powdery drug components and can quickly dissolve in water, which is beneficial to the overflow of the medicament.

[0021] Example Five, based on Example Three, referring to Figure 5 The release film 3 is a rectangular sheet structure with a length of 15 cm and a width of 10 cm, and comprises a release film inner sheet 301 and a release film outer sheet 302 located outside the release film inner sheet 301. The release film inner sheet 301 is an ellipse with a major axis of 7.9 cm and a minor axis of 3.9 cm, and the area of the release film inner sheet 301 is smaller than the bottom area of the drug-loading portion 2. The release film outer sheet 302 comprises two pieces of symmetrical sheet structures located at both ends of the release film inner sheet 301, and both of the two pieces of sheet structures have a circular arc opening, and the openings of the two pieces of sheet structures are both directed towards the release film inner sheet 301. The shape and size of the release film of the present application are consistent with the adhesive portion, and the release film is attached to the adhesive surface of the adhesive portion in the standby state, so that the adhesion of the adhesive surface can be maintained in the unused state. The release film is designed as a release film inner sheet and a release film outer sheet based on the boundary of the drug-loading portion, the release film inner sheet is slightly smaller than the specification of the drug-loading portion, and the remaining part forms the release film outer sheet, which can be individually or entirely removed from the adhesive surface of the adhesive portion according to the requirements.

[0022] Example Six, which is different from Example One, referring to Figure 1、 Figure 2 The middle part of the sticking part 1 is provided with a single-layer capsule structure, the drug loading part 2 does not include a self-sealing containing opening, only has a drug loading part outer layer 201, the drug loading part outer layer 201 seals the single-layer capsule structure, and the single-layer capsule structure is provided with a pre-packaged powdery functional medicament. The single-layer capsule structure pre-packaged powdery functional medicament is used for the occasions of covering and filling compression according to the conventional function in the clinic, and the treatment effect is improved.

[0023] In specific implementation, the application can be made into different specifications and models according to needs, and the drug loading part 2 can be divided into specific areas to contain medicaments with different effects.

[0024] In use, the inner sheet 301 of the release film is torn off, the required medicament is added into the drug loading part 2 through the pre-set self-sealing containing opening, and the drug loading part 2 is sealed for standby, and the drug loading part 2 pre-loaded with the medicament can be directly used; the drug loading part 2 is aligned with the center of the wound and is attached and pressed, the outer sheet 302 of the release film is torn off, and the sticking surface 102 of the sticking part 1 is attached to the skin, so as to seal the wound; according to the amount of bleeding and the characteristics of the wound, the sticking part 1 corresponding to the drug loading part 2 is appropriately pressed, so that the drug loading part 2 is fully contacted with the blood, thereby promoting the dissolution of the inner layer 202 of the drug loading part, so that the internal medicament is fully contacted with the wound to enhance the hemostatic effect, and the drug loading part 2 can also produce a certain packing and pressing effect on the wound after being pressed, thereby further improving the treatment effect of hemostasis. If necessary, the overall pressure of the dressing can be increased from the outside or the dressing can be externally pressed by using a bandage, so as to improve the hemostatic effect; when the use is finished, the dressing can be removed from the wound.

[0025] The application is convenient to use, the process is similar to the conventional dressing method, the use method is simple, and the functions of the application include: 1, powder medicament packaging: the structure of the inner layer 202 and the outer layer 201 of the drug loading part achieves the function of sealing the powdery medicament (which can be pre-sealed or filled in use), the powdery medicament cannot overflow in the sealed bag and has a certain strength and is not easy to be damaged, the packaging of the medicament is obviously reduced in difficulty compared with the general modification process, but the load of the medicament is obviously increased, thereby improving the treatment ability; 2, filling and covering of the wound: the increased structure of the drug loading part 2 enables the hemostatic medicament in the drug loading part to produce the effects of drug hemostasis, physical packing, external pressure and the like together with the dressing to increase the treatment function; 3, release of the packaged medicament: after the drug loading part 2 contacts with the blood, the inner layer 202 of the drug loading part dissolves after meeting water, the powdery medicament components in the inner layer 202 can be quickly and massively released and contacted with the wound, and the pressure of the compression is also conducive to the further contact of the medicament components with the wound surface, thereby improving the local treatment effect; 4, flexible function adjustment: the drug loading part 2 of the dressing can add specific functional treatment medicaments such as hemostatic, analgesic and antibacterial medicaments according to needs, thereby increasing the treatment effect of the dressing on the wound, and making the application scenarios of the dressing more extensive and flexible.

[0026] The present application has simple structure, can flexibly combine and package medicine, is convenient to operate, and is particularly suitable for use when a wound bleeds heavily or other local medicine application is needed, and improves the treatment effect of the dressing.

[0027] The above is only the preferred embodiment of the present application, and it should be pointed out that, for ordinary skilled persons in the art, several improvements and refinements can be made without departing from the principles of the present application, and these improvements and refinements should also be considered as the protection scope of the present application.

Claims

1. A wound dressing that also functions as an encapsulation agent, comprising a sheet-like adhesive portion (1), characterized in that: One side of the adhesive part (1) is the adhesive surface (102), and the other side of the adhesive part (1) is the waterproof surface (101). A release film (3) is provided on the adhesive surface (102). A double-layer capsule structure is provided in the middle of the adhesive part (1). The protruding end of the double-layer capsule structure is away from the release film (3). The double-layer capsule structure is a drug-carrying part (2). The drug-carrying part (2) includes a self-sealing opening. The self-sealing opening is away from the protruding end. The self-sealing opening closes the protruding structure. Powdered drug components can be filled and packaged into the drug-carrying part (2) through the self-sealing opening. The surface of the drug-carrying part (2) close to the release film (3) is flush with the adhesive surface (102) of the adhesive part (1). The self-sealing container includes an outer layer (201) of the drug-carrying part and an inner layer (202) of the drug-carrying part, wherein the inner layer (202) of the drug-carrying part is closer to the release film (3), and the outer layer (201) of the drug-carrying part is farther away from the release film (3). A drug-carrying container (203) is provided between the outer layer (201) of the drug-carrying part and the inner layer (202) of the drug-carrying part. The inner layer (202) of the drug-carrying section is made of any one of the following materials that can be rapidly dissolved in water: starch-PVA, PVA, starch and vegetable oil, or water-soluble yarn. The inner layer (202) of the drug-carrying section contains powdered drugs.

2. The wound dressing with medication encapsulation function according to claim 1, characterized in that: The outer layer (201) of the drug-carrying part is made of medical single-layer gauze.

3. A wound dressing with medication encapsulation function according to claim 2, characterized in that: The release film (3) includes an inner release film sheet (301) and an outer release film sheet (302) located on the outer ring of the inner release film sheet (301). The area of ​​the inner release film sheet (301) is smaller than the bottom area of ​​the drug-loaded part (2).

4. A wound dressing with medication encapsulation function according to claim 3, characterized in that: The release film outer sheet (302) includes two sheet-like structures located at both ends of the release film inner sheet (301).

5. A wound dressing with medication encapsulation function according to claim 4, characterized in that: Both sheet-like structures have arc-shaped openings, and the openings of both sheet-like structures face the inner sheet of the release film (301).

Citation Information

Patent Citations

  • Adhesive bandage

    CN213130289U

  • Covering and filling type wound dressing with medicament packaging function

    CN220495141U