A coagulation analyzer and automatic capping sample injection system

Abstract

The application discloses a puncture and sample adding assembly of automatic capping, wherein a lead screw motor is used as a power source to realize the up-down movement of a puncture needle assembly, and the structure is simple and the cost is reduced. The puncture needle assembly and the capping assembly are connected through a tension spring, and under the driving of the needle transmission assembly, the up-down movement of the capping assembly is realized through the cooperation of the puncture fixing block of the puncture needle assembly and the upper connecting block of the pressing block of the capping assembly; the structure is simple, no extra power source is needed, and the height difference of the anticoagulation blood collection tube can be compatible. The liquid level sensing circuit board is fixed with the sampling needle, the structure can shorten the distance of the liquid level sensing line, and the liquid level sensing sensitivity is improved. The front end of the tow chain is fixedly connected with the puncture needle assembly, and the rear end is fixedly connected with the needle transmission assembly; the tow chain provides a guide function for the wire harness and pipeline rotation, and the structure can protect the pipeline and the line. The application further provides a blood coagulation analyzer using the puncture and sample adding assembly.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of diagnostic equipment, in particular to a coagulation analyzer and a sample feeding system with automatic capping. BACKGROUND

[0002] The fully-automatic coagulation analyzer is a commonly used in-vitro diagnostic testing equipment in clinical laboratories, and is one of the important components of in-vitro diagnostic products. The sample feeding assembly is one of the key components of the fully-automatic coagulation analyzer, and its function is to realize the function of sucking the blood sample from the anticoagulant blood collection tube and spitting the blood sample in the reaction cup. The blood collection tubes used by the current fully-automatic coagulation analyzer are divided into two categories: anticoagulant blood collection tubes with caps and anticoagulant blood collection tubes without caps, so the sample feeding assemblies of the current fully-automatic coagulation analyzer are divided into two categories: one is the sample feeding assembly supporting the anticoagulant blood collection tube without cap, and the other is the sample feeding assembly supporting the anticoagulant blood collection tube with cap. The sample feeding assembly supporting the anticoagulant blood collection tube with cap has the advantages of simple operation and prevention of cross contamination, and gradually replaces the sample feeding assembly supporting the anticoagulant blood collection tube without cap.

[0003] The working principle of the existing sample feeding assembly supporting the anticoagulant blood collection tube with cap is as follows: first, an independent motor drives the capping assembly to press the rubber plug cap of the anticoagulant blood collection tube, and then another independent motor drives the sampling needle to move downward, and the sampling needle reaches the specified height after penetrating the rubber plug cap to suck the sample. Finally, the sampling needle moves upward to pull out from the anticoagulant blood collection tube, and the capping assembly retreats. Finally, the sampling action is completed.

[0004] The existing sample feeding assembly supporting the anticoagulant blood collection tube with cap adopts two independent motors to realize the capping and puncture actions, and its structure is complex and the cost is high. In addition, the anticoagulant blood collection tubes on the market have height differences, and the existing sample feeding assembly cannot well adapt to the height differences. The anticoagulant blood collection tube that is too high will cause the capping to be too tight, and then cause the motor to lose steps and report an error. The anticoagulant blood collection tube that is too low will cause the capping to be not in place, resulting in inaccurate positioning of the anticoagulant blood collection tube, causing the sampling needle to be pierced and bent, and other abnormalities.

[0005] Therefore, the present application proposes a puncture and sample feeding assembly with automatic capping based on years of design experience and practice in the relevant industry to overcome the defects of the prior art. SUMMARY

[0006] Therefore, the present application proposes a puncture and sample feeding assembly with automatic capping based on years of design experience and practice in the relevant industry to overcome the defects of the prior art.

[0007] The present application also provides a coagulation analyzer applying the above-mentioned puncture and sample feeding assembly.

[0008] To achieve the above-mentioned purpose, the present application provides the following technical solutions:

[0009] An automatic capping puncture and sample application assembly, characterized in that it comprises: a capping assembly, a puncture needle assembly, a needle transmission assembly, and a constraint mechanism;

[0010] The needle transmission assembly includes a driving component and a fixing component; the driving component is capable of driving the puncture needle assembly to puncture and retract.

[0011] The constraint mechanism is connected between the cap assembly and the fastener, and the constraint mechanism can provide cap preload force to the cap assembly.

[0012] Preferably, the cap assembly is provided with a first limiting part, and the puncture needle assembly is provided with a second limiting part;

[0013] When the puncture needle assembly is in the retracted position, the second limiting part cooperates with the first limiting part to provide the cap assembly with a limiting support force opposite to the direction of the cap pre-tightening force;

[0014] When the puncture needle assembly is in the puncture position, the second limiting part disengages from the first limiting part.

[0015] Preferably, the pressure cap assembly includes: a pressure cap upper connecting plate; the first limiting portion is disposed on the pressure cap upper connecting plate;

[0016] The puncture needle assembly includes a puncture needle and a puncture fixation block; the puncture needle is mounted on the puncture fixation block, and the second limiting portion is disposed on the puncture fixation block.

[0017] Preferably, the puncture needle assembly further includes: a needle fixing block; the puncture needle is fixed to the puncture fixing block by the needle fixing block, and the needle fixing block is made of engineering plastic;

[0018] And / or, the puncture needle assembly further includes: a circuit board fixing plate and a liquid level sensing circuit board; the circuit board fixing plate is mounted on the puncture fixing block, and the liquid level sensing circuit board is mounted on the circuit board fixing plate.

[0019] Preferably, the constraint mechanism is an elastic element that can provide elastic restoring force as pre-tightening force for the cap assembly.

[0020] Preferably, the constraint mechanism is a tension spring, the connecting plate on the pressure cover has a tension spring hole that mates with the tension spring, and the fixing component is a tension spring fixing block.

[0021] Preferably, the needle transmission assembly further includes: a puncture base, a slidingly fitted second linear guide rail, and a second slider; the driving member, the fixing member, and the second linear guide rail are all disposed on the puncture base;

[0022] The second slider is fixed to the puncture needle assembly;

[0023] The driving member is a lead screw motor, and the needle transmission assembly further comprises a lead screw nut matched with the lead screw motor.

[0024] The lead screw nut is fixed with the second sliding block.

[0025] Preferably, the gland assembly comprises a gland guide rail connecting block, a gland lower connecting plate and a puncture pressing block connected in sequence.

[0026] The needle transmission assembly further comprises a first linear guide rail and a first sliding block in sliding cooperation, the first linear guide rail is parallel to the second linear guide rail, and the gland guide rail connecting block is provided with a mounting hole in fixed cooperation with the first sliding block.

[0027] Preferably, the gland assembly further comprises a positioning pin arranged on the gland guide rail connecting block.

[0028] The puncture base is provided with a movement slot hole matched with the positioning pin, and a movement slot of the movement slot hole is arranged in extension in the direction of the gland.

[0029] Preferably, the puncture pressing block is internally provided with a through hole for the puncture needle of the puncture needle assembly to pass through.

[0030] The bottom of the puncture pressing block is provided with a groove, and the inside of the groove is a conical surface.

[0031] Preferably, the needle transmission assembly further comprises an optical coupler, an optical coupler baffle and an optical coupler connecting plate.

[0032] The optical coupler is installed on the puncture base through the optical coupler connecting plate, and the optical coupler baffle is arranged on the second sliding block.

[0033] Preferably, the needle transmission assembly further comprises a lead screw connecting block, a second drag chain connecting plate, a first drag chain connecting plate and a drag chain.

[0034] One end of the drag chain is installed on the lead screw connecting block through the first drag chain connecting plate, and the lead screw connecting block is installed on the second sliding block.

[0035] The other end of the drag chain is installed on the puncture base through the second drag chain connecting plate.

[0036] A blood coagulation analyzer comprises the automatic gland puncture and sample adding assembly.

[0037] As can be seen from the above technical solution, the automatic gland puncture and sample adding assembly provided by the application adopts a lead screw motor as a power source to realize the up-down movement of the puncture needle assembly, which has simple structure and reduces cost.

[0038] The puncture needle assembly and the cover assembly are connected by a tension spring, and under the driving of a needle transmission assembly, the puncture needle assembly and the cover assembly are driven to move up and down by the cooperation of the puncture fixing block of the puncture needle assembly and the upper connecting block of the pressing block of the cover assembly; the structure is simple and does not need an extra power source, and can be compatible with the height difference of the anticoagulation blood collection tube;

[0039] The liquid level sensing circuit board is fixed with the sampling needle, and the structure can shorten the distance of the liquid level sensing line and improve the liquid level sensing sensitivity;

[0040] The front end of the drag chain is fixedly connected with the puncture needle assembly, and the rear end is fixedly connected with the needle transmission assembly; the drag chain provides a guide for the wire harness and pipeline rotation, and the structure can protect the pipeline and wire. BRIEF DESCRIPTION OF DRAWINGS

[0041] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0042] Figure 1 The assembly structure schematic diagram of the puncture sampling assembly provided by the embodiment of the present application is shown in the figure.

[0043] In the figure, 10 is a cover assembly, 20 is a puncture needle assembly, 30 is a needle transmission assembly, and 50 is a tension spring.

[0044] Figure 2 The assembly structure schematic diagram of the cover assembly provided by the embodiment of the present application is shown in the figure.

[0045] In the figure, 11 is an upper connecting plate of the cover, 12 is a cover guide rail connecting block, 13 is a lower connecting plate of the cover, 14 is a puncture pressing block, and 15 is a positioning pin.

[0046] Figure 3 The assembly structure schematic diagram of the puncture needle assembly provided by the embodiment of the present application is shown in the figure.

[0047] In the figure, 21 is a puncture needle, 22 is a first needle fixing block, 23 is a second needle fixing block, 24 is a puncture fixing block, 25 is a circuit board fixing plate, and 26 is a liquid level sensing circuit board.

[0048] Figure 4 The assembly test structure schematic diagram of the needle transmission assembly provided by the embodiment of the present application is shown in the figure.

[0049] Wherein, 31 is a lead screw motor, 32 is a puncture cover plate, 33 is a lead screw nut, 34 is an optical coupling baffle, 35 is a lead screw connecting block, 36 is a puncture base, 37 is a lead screw fixing block, 38 is a tension spring fixing block, 39 is a first linear guide rail, 40 is a first sliding block, 41 is a second linear guide rail, 42 is a second sliding block, 43 is an optical coupling, and 44 is an optical coupling connecting plate;

[0050] Figure 5 The assembly of the needle transmission assembly is shown in the assembly front view structure schematic diagram provided by the embodiment of the application.

[0051] Wherein, 45 is a second drag chain connecting plate, 46 is a first drag chain connecting plate, and 47 is a drag chain.

[0052] Figure 6 The initial state structure schematic diagram of the puncture and sample adding assembly is shown in the initial state structure schematic diagram provided by the embodiment of the application.

[0053] 60 is an anticoagulant blood collection tube, and 61 is a rubber plug cap.

[0054] Figure 7 The cover pressing state schematic diagram of the puncture and sample adding assembly is shown in the cover pressing state schematic diagram provided by the embodiment of the application.

[0055] Figure 8 The sample suction state schematic diagram of the puncture and sample adding assembly is shown in the sample suction state schematic diagram provided by the embodiment of the application.

[0056] Figure 9 The disengagement state schematic diagram of the puncture and sample adding assembly is shown in the disengagement state schematic diagram provided by the embodiment of the application. DETAILED DESCRIPTION

[0057] The technical solutions in the embodiments of the application will be clearly and completely described below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the application.

[0058] The puncture and sample adding assembly with automatic cover pressing provided by the embodiment of the application comprises a cover pressing assembly 10, a puncture needle assembly 20, a needle transmission assembly 30, and a constraint mechanism 50, and the structure can be referred to the structure shown in the puncture and sample adding assembly with automatic cover pressing provided by the embodiment of the application. Figure 1

[0059] Wherein, the needle transmission assembly 30 comprises a driving member and a fixing member; the driving member can drive the puncture and retreat actions of the puncture needle assembly 20 to realize the puncture and sample suction of the anticoagulant blood collection tube 60.

[0060] The constraint mechanism 50 is connected between the cover pressing assembly 10 and the aforementioned fixing member, and the constraint mechanism 50 can provide a cover pressing pre-tightening force for the cover pressing assembly 10, which can be combined with the constraint mechanism provided by the embodiment of the application. Figures 6-9 ​As shown, the rubber plug cap 61 of the anticoagulant blood collection tube 60 is pressed down.

[0061] As can be seen from the technical solutions described above, the automatic capping puncture and sample adding assembly provided by the embodiment of the application provides a pre-tightening force by the constraint mechanism 50 between the capping assembly 10 and the needle transmission assembly 30, so that the capping assembly 10 is kept pressed against the rubber plug cap 61 during the retraction of the puncture needle assembly 20 (for example, as shown in the initial state of Figure 9 As can be seen from the technical solutions described above, the automatic capping puncture and sample adding assembly provided by the embodiment of the application provides a pre-tightening force by the constraint mechanism 50 between the capping assembly 10 and the needle transmission assembly 30, so that the capping assembly 10 is kept pressed against the rubber plug cap 61 during the retraction of the puncture needle assembly 20 (for example, as shown in the initial state of

[0062] Further, the capping assembly 10 is provided with a first limiting part, and the puncture needle assembly 20 is provided with a second limiting part; when the puncture needle assembly 20 is in the retracted position, as shown in the initial state of Figure 6 the second limiting part cooperates with the first limiting part (visible at the contact between the component 11 and the component 24), providing a limiting support force for the capping assembly 10 in the direction opposite to the capping pre-tightening force, which is upward and away from the anticoagulant blood collection tube 60 here;

[0063] When the puncture action of the puncture needle assembly 20 starts, as shown in the capping state of Figure 7 the second limiting part (visible at the component 24) starts to move away from the first limiting part as the puncture needle assembly 20 moves downward as a whole;

[0064] When the puncture of the puncture needle assembly 20 is completed, as shown in the sample suction state of Figure 8 the second limiting part is completely separated from the first limiting part as the puncture needle assembly 20 is at the lowest position. During the puncture process of the puncture needle assembly 20, the capping assembly 10 always keeps pressing the rubber plug cap 61. By such an arrangement, the capping assembly 10 and the puncture needle assembly 20 are linked together, and can be compatible with the height difference of the anticoagulant blood collection tube 60.

[0065] Specifically, the capping assembly 10 includes a capping upper connecting plate 11, the structure of which can be referred to as shown in Figure 2 The first limiting part described above is arranged on the capping upper connecting plate 11, and a protruding part bent out on the left side of the capping upper connecting plate 11 is visible, and the bottom part is used for contact and cooperation with the second limiting part, as shown in Figure 6

[0066] The puncture needle assembly 20 includes a puncture needle 21 and a puncture fixed block 24, the structures of which can be referred to as shown in Figure 3 The puncture needle 21 is installed on the puncture fixed block 24, and the second limiting part is arranged on the puncture fixed block 24, and a protruding part bent out on the lower left side of the puncture fixed block 24 is visible, and the top part is used for contact and cooperation with the first limiting part, as shown in Figure 6 ​​

[0067] In the embodiment, the puncture needle assembly 20 further comprises a needle fixing block. As shown in the drawings, specifically, the needle fixing block can be in the form of a first needle fixing block 22 and a second needle fixing block 23 matched with each other, and a split structure is adopted to facilitate operation. The puncture needle 21 is fixed to the puncture fixing block 24 through the needle fixing block. The material of the needle fixing block is engineering plastic. The needle fixing block can play an insulation fixing role, and can reduce the interference of metal parts on liquid level sensing, thereby ensuring the sensitivity of liquid level sensing. Figure 3

[0068] In addition, the puncture needle assembly 20 further comprises a circuit board fixing plate 25 and a liquid level sensing circuit board 26. The circuit board fixing plate 25 is installed on the puncture fixing block 24, and the liquid level sensing circuit board 26 is installed on the circuit board fixing plate 25. The liquid level sensing circuit board 26 is installed near the puncture needle liquid level sensing line, so as to shorten the distance between the two to the greatest extent and improve the sensitivity of liquid level sensing.

[0069] As a preferred embodiment, the constraint mechanism 50 is an elastic member, which can provide an elastic restoring force for the gland assembly 10 as a gland pre-tightening force. The constraint mechanism 50 has a simple structure, good constraint and high stability. Of course, the form of the constraint mechanism 50 is not limited to this, and can also be a connecting rod or the like.

[0070] Further, the constraint mechanism 50 is a tension spring, and the upper connecting plate 11 of the gland is provided with a tension spring hole matched with the tension spring. The structure thereof can be referred to as shown in the drawings. Figure 2 Figure 4 The fixing member is a tension spring fixing block 38, which plays a role of fixing the tension spring. The structure thereof can be referred to as shown in the drawings. The tension spring fixing block 38 is installed on the puncture base 36.

[0071] Specifically, the needle transmission assembly 30 further comprises a puncture base 36, a second linear guide rail 41 and a second sliding block 42 matched with each other in sliding. The puncture base 36 serves as the main body of the needle transmission assembly 30, and plays a role of connecting various parts of the needle transmission assembly 30. The driving member, the fixing member and the second linear guide rail 41 are all arranged on the puncture base 36.

[0072] The second sliding block 42 is fixed with the puncture needle assembly 20, forming a sliding pair moving up and down.

[0073] The driving member is a lead screw motor 31. The needle transmission assembly 30 further comprises a lead screw nut 33 matched with the lead screw motor 31.

[0074] The lead screw nut 33 is fixed with the second sliding block 42, so as to change the rotary motion into linear motion, and realize the action of the puncture needle assembly 20. The structure is simple and has high stability.

[0075] In the embodiment, the gland assembly 10 comprises a gland guide rail connecting block 12, a gland lower connecting plate 13 and a puncture pressing block 14 connected in sequence. The structure thereof can be referred to as shown in the drawings.​​Figure 2 as shown;

[0076] The needle transmission assembly 30 further comprises a slidingly fitted first linear guide rail 39 and a first sliding block 40. The structure can refer to Figure 4 as shown. The first linear guide rail 39 is parallel to the second linear guide rail 41, which can realize parallel and same direction linkage of the gland assembly 10 and the puncture needle assembly 20. The gland guide rail connecting block 12 is provided with a mounting hole fixedly fitted with the first sliding block 40, forming a sliding pair moving up and down.

[0077] Further, the gland assembly 10 further comprises a positioning pin 15 arranged on the gland guide rail connecting block 12. The structure can refer to Figure 2 as shown;

[0078] The puncture base 36 is provided with a movement slot hole matched with the positioning pin 15. The movement slot of the movement slot hole is arranged along the gland direction, which provides a limiting effect for the gland assembly 10. It should be noted that the length of the movement slot is matched with the pressing stroke of the gland assembly 10.

[0079] As a preferred, the inside of the puncture pressing block 14 is provided with a through hole for the puncture needle 21 of the puncture needle assembly 20 to pass through. The structure can refer to Figure 2 as shown;

[0080] The bottom of the puncture pressing block 14 is provided with a groove, the inside of which is a tapered surface, which plays a guiding role for the anticoagulant blood collection tube 60 and a role of fixing the anticoagulant blood collection tube 60.

[0081] Specifically, the needle transmission assembly 30 further comprises an optical coupler 43, an optical coupler baffle 34 and an optical coupler connecting plate 45. The structure can refer to Figure 4 as shown;

[0082] Among them, the optical coupler 43 is installed on the puncture base 36 through the optical coupler connecting plate 45, the optical coupler baffle 34 is arranged on the second sliding block 42, and the optical coupler baffle 34 cooperates with the optical coupler 43 to realize the function of vertical in-situ detection.

[0083] Further, the needle transmission assembly 30 further comprises a lead screw connecting block 35, a second drag chain connecting plate 45, a first drag chain connecting plate 46 and a drag chain 47. The structure can refer to Figure 4 as shown;

[0084] Among them, one end of the drag chain 47 is installed on the lead screw connecting block 35 through the first drag chain connecting plate 46, and the lead screw connecting block 35 is installed on the second sliding block 42;

[0085] The other end of the drag chain 47 is installed on the puncture base 36 through the second drag chain connecting plate 45, which provides a guiding and protecting effect for the wire harness and pipeline bending and rotation, thereby improving the service life of the assembly.

[0086] The following is a further description of this solution with reference to specific embodiments:

[0087] The purpose of this invention is to provide an automatic capping puncture and sample application assembly, wherein the needle drive assembly 30 uses a lead screw motor 31 as a power source to realize the up and down movement of the puncture needle assembly 20, which has a simple structure and reduces costs.

[0088] Another objective of this invention is to provide an automatic capping puncture and sample application assembly. A tension spring 50 connects the puncture needle assembly 20 and the capping assembly 10. Driven by the needle drive assembly 30, the capping assembly 10 moves up and down through the cooperation of the puncture fixing block 24 of the puncture needle assembly 20 and the connecting block 11 on the pressure block of the capping assembly 10. Its structure is simple, requires no additional power source, and is compatible with the height difference of the anticoagulant blood collection tubes 60.

[0089] Another objective of the present invention is to provide an automatic capping puncture and sampling assembly in which the liquid level sensing circuit board 26 is fixed together with the sampling needle 21, and its structure can shorten the distance of the liquid level sensing line and improve the liquid level sensing sensitivity.

[0090] Another objective of the present invention is to provide an automatic capping puncture and sample application assembly, wherein the front end of the drag chain 47 is fixedly engaged with the puncture needle assembly 20 and the rear end is fixedly engaged with the needle drive assembly 30. The drag chain 47 provides guidance for the rotation of the wire harness and tubing, and its structure can protect the tubing and wiring.

[0091] This invention relates to an automatic capping puncture and sample dispensing assembly for a fully automated coagulation analyzer, such as... Figure 1 Its structure includes a pressure cap assembly 10, a puncture needle assembly 20, a needle drive assembly 30, and a tension spring 50.

[0092] Puncture needle assembly 20 Figure 2 It consists of a puncture needle 21, a first needle fixing block 22, a second needle fixing block 23, a puncture fixing block 24, a circuit board fixing plate 25, and a liquid level sensing circuit board 26.

[0093] Among them, the puncture fixation block 24, as shown Figure 3 As the main body of the puncture needle assembly 20, it serves to connect the various parts of the puncture needle assembly 20 and transmit the motion generated by the needle transmission assembly 30 to the puncture needle 21.

[0094] The puncture needle 21 is fixed in the second needle fixing block 23 by the first needle fixing block 22. The first needle fixing block 22 is made of engineering plastic PEEK, which serves as insulation and fixing, reducing the interference of metal parts on the liquid level sensing and ensuring the sensitivity of the liquid level sensing.

[0095] The liquid level sensing circuit board 26 is installed on the circuit board fixing plate 25, which can shorten the distance between the liquid level sensing circuit board 26 and the puncture needle 21, and improve the sensitivity of liquid level sensing.

[0096] The cover assembly 10 is as Figure 2 The cover assembly 10 is composed of the upper cover connecting plate 11, the cover guide rail connecting block 12, the lower cover connecting plate 13, the puncture pressing block 14, and the positioning pin 15.

[0097] The cover guide rail connecting block 12 serves as the main body of the cover assembly 10 and connects various parts of the cover assembly 10. The upper end of the cover guide rail connecting block 12 is fixed with the upper cover connecting plate 11, and the lower end is fixed with the lower cover connecting plate 13. The upper part is designed with a positioning hole for installing the positioning pin 15. The middle part is designed with a mounting hole for installing and fixing the first slider 40 of the needle transmission assembly 30.

[0098] The upper cover connecting plate 11 is designed with a tension spring hole for cooperating with the tension spring 50 to form a downward tension.

[0099] The lower cover connecting plate 13 serves to connect the cover guide rail connecting block 12 and the puncture pressing block 14.

[0100] The puncture pressing block 14 is designed with a through hole structure inside for facilitating the puncture needle 21 to pass through. The bottom is designed with a groove matching the shape of the rubber plug cap 61 of the anticoagulant blood collection tube 60. The inside of the groove is designed as a conical surface structure, which serves to guide and fix the anticoagulant blood collection tube 60.

[0101] The positioning pin 15 is fixed in the positioning hole in the cover guide rail connecting block 12 to provide a limiting function for the cover assembly 10.

[0102] The needle transmission assembly 30 is as Figure 4 、 Figure 5 The needle transmission assembly 30 is composed of the lead screw motor 31, the puncture cover plate 32, the lead screw nut 33, the puncture base 36, the lead screw connecting block 35, the optical coupler 43, the optical coupler blocking piece 34, the optical coupler connecting plate 44, the first linear guide rail 39, 40 slider, the second linear guide rail 41, the slider 42, the tension spring fixing block 39, the lead screw fixing block 37, the drag chain 45, the first drag chain connecting plate 46, and the drag chain connecting plate 45.

[0103] The puncture base 36 serves as the main body of the needle transmission assembly 30 and connects various parts of the needle transmission assembly 30. The upper end of the puncture base 36 cooperates with the puncture cover plate 32, the middle part cooperates with the second linear guide rail 42 and the second slider 42, the lower left part cooperates with the first linear guide rail 41 and the first slider 40, the upper left part cooperates with the optical coupler connecting plate 44, and the upper right part cooperates with the second drag chain connecting plate 45. The lower front part cooperates with the lead screw fixing block 37, and the lower rear part cooperates with the tension spring fixing block 38.

[0104] Wherein the lead screw motor 31 and puncture cover plate 32 fixedly matched, play to provide power.

[0105] Wherein the lead screw connecting block 35 and the second slider 42, lead screw nut 33, optocoupler baffle 34, the first drag chain connecting plate 46 cooperate with the second linear guide rail 41 and lead screw motor 31 together constitute linear motion pair.Optocoupler baffle 34 cooperate optocoupler 43 realize vertical in situ detection function.

[0106] Wherein the drag chain 47 connects the first drag chain connecting plate 46, the second drag chain connecting plate 45, its function is for wire harness, pipeline bending rotation provides the guidance and protection function, further improve the component life.

[0107] Wherein the optocoupler 43 is fixed on the optocoupler connecting plate 44, for realizing vertical in situ detection function.

[0108] Wherein the first linear guide rail 39, the first slider 40 is fixed in the puncture base 36 left lower, with the gland assembly 10 cooperation forms linear pair.

[0109] Wherein the lead screw fixed block 37 play to the end protection function of lead screw motor 31.

[0110] Wherein the tension spring fixed block 38 play to the function of fixed tension spring 50.

[0111] Tension spring 50 upper end is fixed in the gland assembly 10 gland on connecting plate 11, lower end is fixed in the needle transmission assembly 30 tension spring fixed block 38, its function is for gland assembly 10 provides the downward pressure, ensure that puncture block 14 can press the anticoagulant blood collection tube 60, prevent the needle when the anticoagulant blood collection tube 60 will not because the friction force of rubber plug cap 61 leads to upward movement.

[0112] The automatic puncture and sample adding assembly of the application is described as follows:

[0113] The initial state of the puncture and sample adding assembly is shown in Figure 6 The whole assembly is in the origin state. At this time, the tension spring 50 is in the maximum extension state, and the tension value is about 50N. The lead screw nut and other parts in the needle transmission assembly 30 are at the uppermost end, and the optocoupler 43 is blocked by the optocoupler baffle 34. The gland assembly 10 is at the highest position due to the puncture fixed block 24 in the needle transmission assembly 30 dragging the gland assembly 10. The puncture needle assembly 20 is at the highest position.

[0114] The screw motor 31 in the needle transmission assembly 30 rotates clockwise, and the screw nut 33 moves vertically downward with the rotation of the screw motor 31. The cap assembly 10 descends with the descent of the puncture fixed block 24 in the needle transmission assembly 30, and stops moving until the positioning pin 15 in the cap assembly 10 abuts against the bottom of the movement slot hole of the puncture base 36 in the needle transmission assembly 30 as shown in Figure 7 At this time, the tension spring 50 is in the state of minimum extension amount, and the tension value is about 30N (after testing, the needle pulling resistance of the anticoagulation blood collection tube with a cap on the market is between 12N and 15N, and in order to ensure that the puncture needle can be pulled out, the pressure provided by the tension spring to the cap assembly should be twice the pressure value of the maximum resistance of the needle pulling), and at the same time, the puncture pressing block 14 of the cap assembly 10 is at the lowest position, which is the lowest limit position 80mm of the anticoagulation blood collection tube 60 (after statistics, the height of the anticoagulation blood collection tube with a cap on the market is between 80mm and 85mm), ensuring that the puncture pressing block 14 can press the anticoagulation blood collection tube 60 with the lowest limit size.

[0115] The screw motor 31 in the needle transmission assembly 30 continues to rotate clockwise, and the screw nut 33 moves vertically downward with the rotation of the screw motor 31. The cap assembly 10 keeps the position unchanged because of the thrust from the bottom of the movement slot hole of the puncture base 36 in the needle transmission assembly 30. In this process, the puncture needle assembly 20 continues to move vertically downward, and the puncture needle pierces the rubber plug cap 61 of the anticoagulation blood collection tube 60. Until the puncture needle 21 senses the liquid level, the puncture needle 21 continues to move downward by a specified distance (8mm, which can absorb a blood sample with a volume of about 600ml), and the screw motor 31 stops rotating. In order to improve the redundancy of the assembly, the lowest position of the puncture needle 21 is designed to be at the bottom of the anticoagulation blood collection tube 60 as shown in Figure 8 .

[0116] After the puncture needle 21 finishes absorbing the blood sample, the screw motor 31 in the needle transmission assembly 30 rotates counterclockwise, and the screw nut 33 moves vertically upward with the rotation of the screw motor 31. The puncture needle 21 is pulled out of the anticoagulation blood collection tube 60 as shown in Figure 9 , and the cap assembly 10 is pulled by the tension F of the tension spring. After calculation, the resistance value f of the rubber plug cap 61 in the anticoagulation blood collection tube 60 is smaller than the tension of the tension spring 50. Therefore, the anticoagulation blood collection tube 60 will not be pulled up.

[0117] The screw motor 31 in the needle transmission assembly 30 continues to rotate counterclockwise, and when the puncture fixed block 24 in the puncture needle assembly 20 contacts the cap upper connecting block 11 of the cap assembly 10, the puncture needle 21 has been pulled out of the anticoagulation blood collection tube 60, and the pressure provided by the cap assembly 10 is no longer needed. The screw motor 31 continues to rotate counterclockwise, and at the same time, the cap assembly 10 moves vertically upward until the original point photoelectric coupler 43 is triggered to stop moving and complete the puncture and sample absorption action of this round as shown in Figure 6.

[0118] Throughout the puncture and sampling process, the drag chain 47 moves up and down with the lead screw connecting block 35 in the needle drive assembly 30, providing guidance and protection for the bending and rotation of the line and pipeline.

[0119] This invention also provides a coagulation analyzer, including the automatic capping puncture and sample dispensing assembly as described above.

[0120] The automatic capping puncture and sample application assembly of the present invention has the following key features:

[0121] (1) This invention uses a tension spring and a lead screw motor to achieve the vertical movement of the puncture needle assembly and the pressure cap assembly through a simple structure. Unlike existing dual-motor independent control, this structure effectively reduces component costs because the mechanical structure used for motion transmission provides higher stability.

[0122] (2) The present invention proposes that the height of the capped anticoagulant blood collection tubes on the market is between 80mm and 85mm. Because the capping assembly is required to press down all the anticoagulant blood collection tubes, the present invention adopts the minimum limit size of 80mm to ensure that it can be adapted to all sizes of anticoagulant blood collection tubes.

[0123] (3) The present invention proposes that the needle removal resistance of the capped anticoagulant blood collection tubes on the market is between 12N and 15N after testing. In order to ensure that the puncture needle can be pulled out, the pressure of the capping assembly given by the tension spring should be twice the pressure value of the maximum needle removal resistance, i.e., 30N.

[0124] (4) This invention proposes that the puncture needle should be insulated from metal parts. Therefore, the first and second needle fixing blocks are made of engineering plastic PEEK to achieve insulation and fixing, which can reduce the interference of metal parts on liquid level sensing and ensure the sensitivity of liquid level sensing. In addition, the structure here is simple and easy to install and debug.

[0125] (5) This invention proposes that the sensitivity of the liquid level sensing of the puncture needle is related to the distance between the liquid level sensing circuit board and the liquid level sensing line between the puncture needle; the shorter the distance, the more sensitive the liquid level sensing. This invention installs the liquid level sensing circuit board near the liquid level sensing line of the puncture needle to minimize the distance between them and improve the sensitivity of the liquid level sensing.

[0126] The present application relates to a kind of automatic pressing cap's puncture sample adding assembly in automatic coagulation analyzer.The structure includes cap assembly 10, puncture needle assembly 20, needle transmission assembly 30, tension spring 50.The first linear guide 39 is designed in the side of needle transmission assembly 30, the first slider 40 in the first linear guide 39 in cap assembly 10 and needle transmission assembly 30 is fixedly installed, forms a sliding pair of up and down movement.The upper end of tension spring 50 is fixedly matched with cap assembly 10, the lower end is fixedly matched with needle transmission assembly 30, provides a downward tension to cap module 10.The second linear guide 41 is designed in the middle position of needle transmission assembly 30, the second slider 42 in the second linear guide 41 in puncture needle assembly 20 and needle transmission assembly 30 is fixedly installed, forms another sliding pair of up and down movement.Needle transmission assembly 30 designs drag chain 47, the front end of drag chain 47 is matched with screw connecting block 35 through first drag chain connecting plate 46, the rear end is matched with puncture base 36 through second drag chain connecting plate 45, and the function of drag chain 47 is to provide guiding for wire harness rotation.The feature of the present application is that needle transmission assembly provides the power source for the vertical movement of puncture needle assembly 20 by a screw motor 31, and tension spring 50 provides the pressure of cap assembly 10 against anticoagulant blood collection tube during needle extraction, and the calculation of pressure value can ensure that anticoagulant blood collection tube is not pulled up.

[0127] Each embodiment in the specification is described in a progressive manner, and each embodiment focuses on the difference from other embodiments, and the same or similar parts between each embodiment can be referred to each other.

[0128] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present application. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to these embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An automatic capping puncture and sample application assembly, characterized in that, include: The pressure cap assembly (10), the puncture needle assembly (20), the needle drive assembly (30), and the restraint mechanism (50); The needle drive assembly (30) includes a drive member and a fixing member; the drive member is capable of driving the puncture needle assembly (20) to puncture and retract; The constraint mechanism (50) is connected between the cap assembly (10) and the fastener, and the constraint mechanism (50) can provide cap preload force to the cap assembly (10); The cap assembly (10) is provided with a first limiting part, and the puncture needle assembly (20) is provided with a second limiting part; when the puncture needle assembly (20) is in the retracted position, the second limiting part cooperates with the first limiting part to provide the cap assembly (10) with a limiting support force opposite to the direction of the cap pre-tightening force; when the puncture needle assembly (20) is in the puncture position, the second limiting part disengages from the first limiting part; The pressure cap assembly (10) includes: a pressure cap upper connecting plate (11); the first limiting part is disposed on the pressure cap upper connecting plate (11); the puncture needle assembly (20) includes: a puncture needle (21) and a puncture fixing block (24); the puncture needle (21) is mounted on the puncture fixing block (24), and the second limiting part is disposed on the puncture fixing block (24). The needle transmission assembly (30) further includes: a puncture base (36), a slidingly fitted second linear guide rail (41), and a second slider (42); the driving component, the fixing component, and the second linear guide rail (41) are all disposed on the puncture base (36); the second slider (42) is fixed to the puncture needle assembly (20); the driving component is a lead screw motor (31), and the needle transmission assembly (30) further includes: a lead screw nut (33) that cooperates with the lead screw motor (31); the lead screw nut (33) is fixed to the second slider (42); The cap assembly (10) includes: a cap guide rail connecting block (12), a cap lower connecting plate (13), and a puncture pressure block (14) connected in sequence; the needle transmission assembly (30) further includes: a first linear guide rail (39) and a first slider (40) that are slidably engaged; the first linear guide rail (39) is parallel to the second linear guide rail (41), and the cap guide rail connecting block (12) has a mounting hole that is fixedly engaged with the first slider (40); The needle drive assembly (30) further includes: a lead screw connecting block (35), a second drag chain connecting plate (45), a first drag chain connecting plate (46), and a drag chain (47); one end of the drag chain (47) is mounted on the lead screw connecting block (35) through the first drag chain connecting plate (46), and the lead screw connecting block (35) is mounted on the second slider (42); the other end of the drag chain (47) is mounted on the puncture base (36) through the second drag chain connecting plate (45).

2. The automatic capping puncture and sample application assembly according to claim 1, characterized in that, The puncture needle assembly (20) further includes: a needle fixing block; the puncture needle (21) is fixed to the puncture fixing block (24) by the needle fixing block, and the needle fixing block is made of engineering plastic; And / or, the puncture needle assembly (20) further includes: a circuit board fixing plate (25) and a liquid level sensing circuit board (26); the circuit board fixing plate (25) is mounted on the puncture fixing block (24), and the liquid level sensing circuit board (26) is mounted on the circuit board fixing plate (25).

3. The automatic capping puncture and sample application assembly according to claim 1, characterized in that, The constraint mechanism (50) is an elastic element that can provide elastic restoring force as pre-tightening force for the cap assembly (10).

4. The automatic capping puncture and sample application assembly according to claim 1, characterized in that, The constraint mechanism (50) is a tension spring, the connecting plate (11) on the cover has a tension spring hole that cooperates with the tension spring, and the fixing member is a tension spring fixing block (38).

5. The automatic capping puncture and sample application assembly according to claim 1, characterized in that, The cap assembly (10) further includes a positioning pin (15) disposed on the cap guide rail connecting block (12). The puncture base (36) has a movement groove that cooperates with the positioning pin (15), and the movement groove of the movement groove extends along the pressure cap direction.

6. The automatic capping puncture and sample dispensing assembly according to claim 1, characterized in that, The puncture pressure block (14) has a through hole inside, through which the puncture needle (21) of the puncture needle assembly (20) passes; The bottom of the puncture block (14) is provided with a groove, and the interior of the groove is a conical surface.

7. The automatic capping puncture and sample dispensing assembly according to claim 1, characterized in that, The needle drive assembly (30) further includes: an optocoupler (43), an optocoupler baffle (34), and an optocoupler connecting plate (44). The optocoupler (43) is mounted on the puncture base (36) via the optocoupler connecting plate (44), and the optocoupler baffle (34) is disposed on the second slider (42).

8. A coagulation analyzer, characterized in that, The puncture and sample application assembly includes the automatic capping assembly as described in any one of claims 1-7.

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