occlusion device

Abstract

The application relates to a blocking device, comprising a fixing part, the fixing part comprising a plurality of support bodies, the plurality of support bodies comprising a plurality of supporting segments arranged at intervals along the circumferential direction of the fixing part, the supporting segments being provided with anchoring structures, the anchoring structures comprising anchoring pieces and limiting pieces capable of exerting stress on the anchoring pieces, the limiting pieces comprising a first state and a second state, the opening angle of the free end of the anchoring piece in the first state being greater than the opening angle of the free end of the anchoring piece in the second state. When the anchoring piece is pierced into the inner wall of the left atrial appendage in the first state, the anchoring piece retains a large enough opening angle for easy piercing, after the left atrial appendage wall is pierced to the second state, the anchoring piece moves inward, the opening angle is reduced, so that the anchoring piece is closer to the side of the blocking device, thereby avoiding piercing the left atrial appendage wall, the anchoring piece can be longer, thereby improving the anchoring capacity of the whole device.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of interventional medical devices, and in particular to a closure device. BACKGROUND

[0002] In recent years, among non-valvular atrial fibrillation patients, 90% of the brain strokes caused by atrial fibrillation are derived from the left atrial appendage. Clinical data shows that when atrial fibrillation occurs, the removal of the left atrial appendage in cardiac surgery can reduce the incidence of brain stroke, which indicates the danger of the left atrial appendage in thromboembolism. Since the left atrial appendage is the nidus of thrombus, occluding the opening of the left atrial appendage can eliminate the basis of thrombus formation in the left atrial appendage. Generally, occluding the left atrial appendage by a left atrial appendage occluder is an effective way to prevent brain stroke caused by atrial fibrillation.

[0003] To effectively occlude the left atrial appendage, the left atrial appendage occluder needs to be implanted in the left atrial appendage for a long time to achieve the occlusion effect. Therefore, the left atrial appendage occluder needs to have a certain anchoring structure to stably occlude the left atrial appendage opening for a long time, and to avoid the problem of device embolization caused by its falling off.

[0004] To achieve the long-term stability of the left atrial appendage occluder in the left atrial appendage opening, a large number of anchoring structures with sharp tips, such as anchor spikes or anchor hooks, are usually arranged on the support part of the left atrial appendage occluder (the junction of the left atrial appendage occluder and the atrial wall) to penetrate into the atrial wall and achieve the stability of long-term implantation. At the same time, since the atrial appendage undergoes systolic and diastolic movement with the heart, the anchoring structure ensures the close contact between the occlusion device and the inner wall of the left atrial appendage. However, after the left atrial appendage occluder is implanted, due to the influence of radial force and atrial systolic and diastolic movement, the anchor spike may penetrate too deeply and thus pierce the atrial wall, resulting in pericardial effusion or puncture of other blood vessels. However, if the anchor spike is too short, the anchoring effect will be weak, and a too small opening angle of the anchor spike will also cause the anchor spike to fail to penetrate into the left atrial appendage wall. SUMMARY

[0005] Therefore, it is necessary to provide an improved occlusion device to solve the problem of the anchor spike of the existing left atrial appendage occluder easily piercing the left atrial appendage wall.

[0006] An occlusion device includes a fixed part, the fixed part includes a plurality of support bodies, the plurality of support bodies include a plurality of support segments arranged at intervals in a circumferential direction of the fixed part, the support segments are provided with anchoring structures, the anchoring structures include anchor pieces and limiting pieces capable of applying force to the anchor pieces, the limiting pieces include a first state and a second state, and the opening angle of the free end of the anchor piece in the first state is greater than the opening angle of the free end of the anchor piece in the second state.

[0007] In one embodiment, from the first state to the second state, the anchor pieces converge towards the direction of the support segments.

[0008] In one of the embodiments, the supporting section comprises a proximal section and a distal section, and the limiting member is at least partially located between the proximal section and the anchoring member.

[0009] In one of the embodiments, one end of the limiting member is connected to the anchoring member, and the other end is connected to the supporting section.

[0010] In one of the embodiments, one end of the limiting member is rotatably connected to the anchoring member, and the other end is slidably connected to the supporting section.

[0011] In one of the embodiments, one end of the limiting member is slidably connected to the anchoring member, and the other end is rotatably connected to the supporting section.

[0012] In one of the embodiments, the limiting member is at least partially located between the distal section and the anchoring member, and in the first state, the limiting member is taut on the anchoring member.

[0013] In one of the embodiments, the anchoring member comprises a plurality of blocking pieces arranged axially along the surface of the anchoring member, and one end of the limiting member is sleeved on the blocking pieces.

[0014] In one of the embodiments, in the first state, one end of the limiting member is sleeved on the blocking piece located at the proximal end.

[0015] In one of the embodiments, the limiting member comprises a baffle structure or a mesh structure.

[0016] Compared with the prior art, in the first state of penetrating into the inner wall of the left atrial appendage, the anchoring member retains a large enough opening angle for easy penetration, and in the second state of penetrating into the left atrial appendage wall, the anchoring member moves inward and the opening angle decreases, so that the anchoring member is closer to the side of the occlusion device, thereby avoiding piercing the left atrial appendage wall. Under such design, the anchoring member can be longer, thereby improving the overall anchoring capacity of the device. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 FIG. 1 is a working schematic diagram of the occlusion device in Example 1;

[0018] Figure 2 FIG. 2 is a structural schematic diagram of the occlusion device in Example 1;

[0019] Figure 3 FIG. 3 is an enlarged schematic diagram of area A in FIG. 2; Figure 2

[0020] Figure 4 FIG. 4 is a structural schematic diagram of the anchoring structure of the occlusion device in another embodiment of Example 1;

[0021] FIG. 5 is a structural schematic diagram of the anchoring structure of the occlusion device in another embodiment of Example 1.Figure 5 Structure diagram of the anchoring structure of the occlusion device in Example 2 in a natural state;

[0022] Figure 6 Cross-sectional structure diagram of the anchoring structure of the occlusion device in Example 2 in a natural state;

[0023] Figure 7 Structure diagram of the anchoring structure of the occlusion device in Example 3 in a natural state;

[0024] Figure 8 Structure diagram of the anchoring structure of the occlusion device in Example 3 in a natural state without the limiting member;

[0025] Figure 9 Structure diagram of the anchoring structure of the occlusion device in Example 3 in a natural state;

[0026] Figure 10 Structure diagram of the anchoring structure of the occlusion device in another embodiment of Example 3 in a natural state. DETAILED DESCRIPTION

[0027] In order to make the objects, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with reference to the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and do not limit the present application.

[0028] It should be noted that in the field of interventional medical devices, the end of a medical device implanted in a human or animal body closer to an operator is generally referred to as the "proximal end", and the end farther from the operator is generally referred to as the "distal end", and the "proximal end" and "distal end" of any component of the medical device are defined according to this principle. The "axial direction" generally refers to the length direction of the medical device when it is being delivered, and the "radial direction" generally refers to the direction perpendicular to the "axial direction" of the medical device, and the "axial direction" and "radial direction" of any component of the medical device are defined according to this principle. The "connection" mentioned in the embodiments includes the case where two components are directly connected and the case where two components are indirectly connected through other components.

[0029] The technical solutions of the present application will be further described in detail below with reference to specific embodiments.

[0030] Example 1

[0031] The occlusion device proposed in Example 1 can be used to occlude the left atrial appendage, and can also be used to occlude other in-vivo tissues having openings, such as atrial septal defects. The occlusion device will be described in detail below with the occlusion of the left atrial appendage as an example.

[0032] Reference is made to Figure 1 , Figure 1is a working schematic view of the occlusion device 100, which comprises a sealing portion 110 and a fixing portion 120 connected with the sealing portion 110. The sealing portion 110 and the fixing portion 120 are arranged in the axial direction of the occlusion device 100. The sealing portion 110 is located at the proximal end of the occlusion device 100, and the fixing portion 120 is located at the distal end of the occlusion device 100. The occlusion device 100 has a compressed state for being accommodated in a sheath tube for convenient transportation, and an expanded state as shown after being extended from the distal end of the sheath tube and self-expanding and unfolding. The occlusion device 100 has the same or substantially the same shape as Figure 1 after being released in the cavity of the left atrial appendage 130. In other implementations, for example, for atrial septal defect occlusion, the sealing portion 110 and the fixing portion 120 can abut each other after being released to fix the occlusion device 100 on the septum between the left atrium and the right atrium. Figure 1

[0033] The sealing portion 110 is woven into a mesh tube by a plurality of woven wires 111, and the ends of the woven wires 111 are closed and fixed by a sleeve at both ends of the mesh tube. Then, the mesh tube is heat set into a disc shape, a column shape or a plug shape, thereby obtaining the sealing portion 110 for occluding the opening of the left atrial appendage 130. The sealing portion 110 comprises a distal disc surface 112 facing the fixing portion 120, and a proximal disc surface 113 opposite to the distal disc surface 112. The sealing portion 110 is internally provided with at least one film body (not shown in the figure), and the edge of the film body is fixed on the woven wires 111 at the edge of the sealing portion 110. The film body 114 is used to prevent blood flow from one side of the sealing portion 110 to the other side, so as to prevent blood flow between the left atrial appendage 130 and the left atrium.

[0034] The fixing portion 120 comprises a central end portion 121 and a plurality of support bodies 122, and the distal sleeve 115 of the sealing portion 110 is connected with the central end portion 121. The support bodies 122 on the fixing portion 120 can be rods obtained by cutting a metal alloy pipe or a polymer pipe, or can be rods made of the woven wires 111 by weaving or winding.

[0035] The proximal ends of the plurality of support bodies 122 are connected with the central end portion 121, and the distal ends thereof extend radially outward from the central end portion 121 and turn towards the sealing disc, thereby forming a turning section 123. The support bodies 122 continue to extend towards the sealing portion 110 from the distal end of the turning section 123, thereby forming a supporting section 124, which is used to abut the left atrial appendage 130. The supporting section 124 continues to extend towards the sealing portion 110, thereby forming a hanging section 126. The hanging section 126 can continue to extend along the direction of the supporting section 124, or can deflect and turn inward of the supporting section 124, so as to avoid damaging the left atrial appendage 130.

[0036] As shown in Figure 1 ​As shown, the outer side of the supporting section 124 is provided with an anchoring structure 125 which is inclined outward and towards the sealing section 110, and the anchoring structure 125 includes a thorn-like structure at its tip. After the occlusion device 100 is implanted, the anchoring structure 125 is anchored by its thorn-like structure piercing into the inner wall of the left atrial appendage 130, thereby anchoring the entire occlusion device 100. On the one hand, since the thickness of the wall of the left atrial appendage 130 is generally less than 3mm, this limits the radial length of the thorn-like structure to be less than the thickness of the wall of the left atrial appendage 130. On the other hand, since the piercing angle of the anchoring structure 125 is the extension angle of the thorn-like structure, i.e. the angle of the thorn-like structure relative to the axis, and in the prior art, the anchoring structure 125 is pierced into the left atrial appendage occluder by the restoring force of the restoring force of the fixed section 120 to restore the natural shape, and since the anchoring structure 125 is actually also deformable, the free end of the anchoring structure 125 in the prior art must have a certain opening angle (i.e. the deflection angle relative to the axis) so as to pierce into the inner wall of the left atrial appendage. If the opening angle is too small, the anchoring structure 125 is easily compressed and deformed by the inner wall of the left atrial appendage, thereby sticking to the surface of the supporting section 124, and although the fixed section 120 is fully opened, the anchoring function is still not achieved. The longer the total length of the anchoring structure 125 implanted, i.e. the longer the length of the anchoring structure 125 pierced into the inner wall of the left atrial appendage, the better the anchoring ability of the entire occlusion device 100. Therefore, the length of the anchoring structure 125 should be as long as possible.

[0037] In another embodiment, the outer part of the fixed section 120 is covered with a film to further occlude the left atrial appendage while ensuring that the sealing section 1100 can achieve sealing, and to avoid excessive stress on the surface of the fixed section, and when the anchoring member 1125 of the fixed section 120 pierces into the inner wall of the left atrial appendage to cause a micro-wound, the film can block the root of the anchoring member 125 to prevent blood from flowing out of the micro-wound and accelerate the rapid coverage of the micro-wound.

[0038] Therefore, in view of the above-mentioned needs, the anchoring device 125 in the occlusion device 100 provided in the present embodiment is specially designed.

[0039] As shown in Figures 2-3 , the occlusion device 100 provided in the present embodiment is a structure schematic view, Figure 2 , the occlusion device 100 provided in the present embodiment is a structure schematic view, Figure 3 , the occlusion device 100 provided in the present embodiment is a structure schematic view, Figure 2An enlarged schematic view of the middle A region. The anchoring structure 125 includes an anchor 1251 and a limiting member 1252. In this embodiment, the anchor 1251 includes an anchor spike, and the limiting member 1252 includes a tether. The tether can be made of a high polymer material such as PP, PET, PTFE, or a metal material with good biocompatibility such as SI6LV or nickel-titanium. The connecting end of the anchor 1251 is arranged on the support section 124, and the free end extends outward. In this embodiment, the connecting end of the anchor 1251 is located at the distal end, and the free end of the anchor 1251 is located at the proximal end, which serves as the first spike end to penetrate into the left atrial appendage. The limiting member 1252 is connected to the free end of the anchor 1251 or the side close to the free end.

[0040] In this embodiment, the limiting member 1252 includes a tether, and the end of the limiting member 1252 is connected to a stop block 1253 to prevent the limiting member 1252 from detaching from the anchor 1251. The support section 124 is divided into a distal support section 1241 and a proximal support section 1242 by the connecting end of the limiting member 1252. One end of the limiting member 1252 is fixed to the proximal support section 1242 (or can be arranged on the overhanging section 126), and the other end is connected or movably connected to the anchor 1251.

[0041] During the entire implantation of the occlusion device, the free end of the anchor 1251 penetrates into the inner wall of the left atrial appendage, and part of the tissue of the left atrial appendage is located between the anchor 1251 and the proximal support section 1242 at this time. As the free end of the anchor 1251 continues to penetrate, the tissue of the left atrial appendage will gradually fill the gap between the anchor 1251 and the proximal support section 1242, i.e., part of the tissue of the left atrial appendage moves relative to the occlusion device 100.

[0042] When the tissue of the left atrial appendage fills the gap between the anchor 1251 and the proximal support section 1242, the tissue of the left atrial appendage will also resist the movement of the limiting member 1252 because the limiting member 1252 is interposed between the anchor 1251 and the proximal support section 1242. Since the filling direction of the tissue is from the proximal end to the distal end of the anchor 1251 and the proximal support section 1242, the middle part of the limiting member 1252 is driven to move towards the distal end (i.e. the connecting end of the anchor 1251). Since the limiting member 1252 is fixed between the proximal support section 1242 and the anchor 1251, the limiting member 1252 will pull the proximal support section 1242 and the anchor 1251 to close. Since the support section 124 is much larger than the anchor 1251 as a whole, and after the anchor 1251 pierces into the left atrial appendage, the other tissue of the left atrial appendage that is not located between the anchor 1251 and the proximal support section 1242 resists the support section 124. Therefore, as a whole, the limiting member 1252 drives the anchor 1251 to close towards the proximal support section 1242. Therefore, after the anchor 1251 pierces into the left atrial appendage, the opening angle of the anchor 1251 relative to the proximal support section 1242 becomes smaller, i.e. the opening angle relative to the axis becomes smaller, thereby further reducing the risk of the anchor 1251 piercing the wall of the left atrial appendage, and at the same time enabling the anchor 1251 to have a longer preset length, thereby enhancing the anchoring capability of the entire occlusion device 100.

[0043] Further, as the anchor 1251 gradually pierces into the left atrial appendage, the tissue between the proximal support section 1242 and the anchor 1251 is further filled, thereby further driving the limiting member 1252 to move towards the connecting end of the anchor 1251, and further driving the free end of the anchor 1251 to close towards the axis, so that the opening angle of the free end is further reduced. Therefore, after the anchor 1251 pierces, the free end of the anchor 1251 will be driven by the tension to extend in an arc shape obliquely towards the proximal end. The tangent line at the position of the free end of the anchor 1251 has an angle smaller than the opening angle of the free end of the anchor 1251 in the natural state relative to the axis. Here, the natural state is the initial state of the occlusion device 100 after leaving the sheath due to the presence of the limiting member 1252.

[0044] In another embodiment, the limiting member 1252 is in the form of a baffle structure or a mesh structure, which can reduce the stimulation to the tissue of the left atrial appendage.

[0045] In another embodiment, the limiting member 1252 is an elastic member, so that the stress is more uniform when the limiting member 1252 is bent.

[0046] In another embodiment, with reference to Figure 4 , Figure 4As shown in the structural diagram of the anchoring structure of the occlusion device in this embodiment, the free end of the anchor 1351 is in a hook shape, which can reduce the initial penetration angle of the anchor 1351 and reserve a longer length of the anchor 1351 to increase the anchoring capacity.

[0047] Embodiment 2

[0048] This embodiment is improved based on Embodiment 1, and the difference from Embodiment 1 is that the limiting member is in sliding connection with the anchor, as shown in Figures 5-6 Figure 5 As shown in the structural diagram of the anchoring structure of the occlusion device in this embodiment in a natural state; Figure 6 As shown in the cross-sectional diagram of the anchoring structure of the occlusion device in this embodiment in a natural state.

[0049] The anchor 1451 extends outward from the support section, and the junction of the distal support section 1441 and the proximal support section 1442 is the connecting end of the anchor 1451. The limiting member 1452 is in the shape of a rod, one end of which is in rotational connection with the proximal support section 1442, and the other end is in sliding connection with the anchor 1451. The anchor 1451 is provided with a sliding groove for the end of the limiting member 1452 to slide. The limiting member 1452 is in rotational connection with the proximal support section 1442 and in sliding connection with the anchor 1451. When the limiting member 1452 is perpendicular to or close to perpendicular to the anchor 1451, the opening angle of the anchor 1451 is the largest.

[0050] In a natural state, the opening angle of the anchor 1451 is the largest, and the anchor 1451 is supported by the limiting member 1452. After the limiting member 1452 is removed, the opening angle of the anchor 1451 becomes smaller. When the anchor 1451 is deployed in a natural state, the opening angle of the anchor 1451 is larger, which facilitates the penetration of the anchor 1451 into the left atrial appendage.

[0051] After the anchor 1451 penetrates into the left atrial appendage, part of the tissue of the left atrial appendage enters between the anchor 1451 and the proximal support section 1442. As the anchor 1451 gradually penetrates, the tissue pushes the limiting member 1452 to move towards the distal end. Since one end of the limiting member 1452 is in rotational connection with the proximal support section 1442 and the other end is in sliding connection with the sliding groove of the anchor 1451, the tissue drives the end of the limiting member 1452 to move, which drives the anchor 1451 to gradually restore to the original state and gradually reduce the opening angle. Finally, the tangent at the position of the free end of the anchor 1451 (i.e., the opening angle at the position of the free end) is smaller than the opening angle of the free end of the anchor 1451 in a natural state.

[0052] ​In another embodiment, the limiting member 1452 is a rod, one end of which is connected to the anchoring member 1451 in a rotating manner, and the other end is connected to the proximal supporting section in a sliding manner, that is, the sliding groove is arranged on the supporting section, and the principle is consistent with that of embodiment 2.

[0053] Embodiment 3

[0054] This embodiment is improved based on embodiment 1, and the difference from embodiment 1 is that the connecting manner of the limiting member and the anchoring member is different. For details, refer to Figures 7-9 , Figure 7 is a structural schematic diagram of the anchoring structure of this embodiment in a natural state, Figure 8 is a structural schematic diagram of the anchoring structure of this embodiment in a natural state without the limiting member, the anchoring member 1551 extends outward from the supporting section, the junction of the distal supporting section 1541 and the proximal supporting section 1542 is the connecting end of the anchoring member 1551, the limiting member 1552 is a tether, one end of which is fixedly connected to the distal supporting section 1541, and the other end is movably connected to the anchoring member 1551. In this embodiment, a sleeve is selected, and the anchoring member 1551 is provided with a plurality of blocking pieces 1553 arranged in sequence from the proximal end to the distal end on the surface of the anchoring member 1551. The limiting member 1552 pulls the blocking pieces of the anchoring member 1551, so that the opening angle α of the anchoring member 1551 is greater than the opening angle β of the anchoring member 1551 without tension.

[0055] When the limiting member 1552 is sleeved on the blocking piece 1553 closest to the proximal end of the anchoring member 1551, the pulling force of the limiting member 1552 on the anchoring member 1551 is the largest, and the opening angle of the anchoring member 1551 is the largest. At this time, the anchoring member 1551 is relatively easy to pierce into the left atrial appendage. After piercing into the left atrial appendage, the tissue of the left atrial appendage is fitted to the sharp end of the anchoring member 1551 and moves towards the connecting end of the anchoring member 1551, and the tissue drives the ring sleeve closest to the proximal end of the limiting member 1552, so that the limiting member 1552 sequentially moves to the blocking piece 1553 farther away from the proximal end, so that the opening angle of the anchoring member 1551 gradually decreases.

[0056] It should be noted that the design of the plurality of blocking pieces 1553 is to make the process of restoring the opening angle of the anchoring member 1551 more smooth, and it is not necessary to design a plurality of blocking pieces 1553 to achieve this technical effect.

[0057] Further, in order to increase the contact area of the left atrial appendage to the limiting member 1552 on the anchoring member 1551, the distal end of the limiting member 1552 can also be provided with a baffle structure to reduce the stimulation to the tissue of the left atrial appendage.

[0058] For reference Figure 9 , Figure 9is a structural schematic view of the anchor of the embodiment, a plurality of stop flaps 1553 are arranged on the anchor 1551, in order to avoid the limiting member 1552 being unable to be separated from the stop flaps 1553 due to the extrusion of the left atrial appendage, the distal end face of the stop flaps 1553 and the surface of the anchor 1551 are preferably obtuse angles, and are further preferably 90°-135°.

[0059] In another embodiment, the limiting member is in the structure of an elastic member, referring to Figure 10 , Figure 10 is a structural schematic view of the anchor structure of the embodiment in a natural state, the limiting member 1652 is selected from elastic members, including springs, elastic ropes and the like, and is in a stretched state in an initial state, and has a restoring force to restore to the original state, so that when the left atrial appendage tissue exerts a small stress on the proximal end of the limiting member 1652, the limiting member 1652 can also rebound, and then further makes the opening angle of the anchor 1651 rebound to be smaller, thereby reducing the stimulation to the left atrial appendage tissue.

[0060] The technical features of the above embodiments can be combined arbitrarily, in order to make the description simple, all possible combinations of the technical features in the above embodiments are not described, however, as long as the combinations of the technical features do not exist contradictory, it should be considered that the scope of the present application is recorded.

[0061] The above embodiments only express several embodiments of the present application, the description is more specific and detailed, but it should not be understood as the limitation of the scope of the patent. It should be pointed out that for ordinary skilled in the art, without departing from the concept of the present application, a number of variations and improvements can be made, which belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. An occlusive device comprising a fixed portion, the fixed portion comprising a plurality of support bodies, the plurality of support bodies comprising a plurality of support segments spaced along a circumferential direction of the fixed portion, characterized in that, The supporting section is provided with an anchoring structure, which comprises an anchor and a limiting member capable of exerting force on the anchor, the limiting member comprising a first state in a natural state and a second state in a working state after implantation, the opening angle of the free end of the anchor in the first state being greater than that in the second state, the supporting section comprising a proximal section, during the change from the first state to the second state, the limiting member drives the anchor to close towards the direction of the proximal section, and the opening angle of the anchor relative to the proximal section becomes smaller.

2. The occlusion device of claim 1, wherein, From the first state to the second state, the anchor closes towards the direction of the supporting section.

3. The occlusion device of claim 1, wherein, The supporting section comprises a distal section, and the limiting member is at least partially located between the proximal section and the anchor.

4. The occlusion device of claim 3, wherein, One end of the limiting member is connected to the anchor, and the other end is connected to the supporting section.

5. The sealing device according to claim 4, characterized in that, One end of the limiting member is rotationally connected to the anchor, and the other end is slidingly connected to the supporting section.

6. The occlusion device of claim 4, wherein, One end of the limiting member is slidingly connected to the anchor, and the other end is rotationally connected to the supporting section.

7. The occlusive device of claim 2, wherein, The supporting section comprises a distal section, and the limiting member is at least partially located between the distal section and the anchor, and in the first state, the limiting member tightens the anchor.

8. The occlusion device of claim 7, wherein, The anchor comprises a plurality of blocking pieces arranged axially along the surface of the anchor, and one end of the limiting member is sleeved on the blocking piece position.

9. The occlusion device of claim 8, wherein, In the first state, one end of the limiting member is sleeved on the blocking piece position located at the proximal end.

10. The occlusion device of any of claims 1-9, wherein, The limiting member comprises a baffle structure or a mesh structure.

Images