Heterocyclic compound and pest control composition containing the same
By using a specific heterocyclic compound or a composition of its nitrogen oxide, the problem of difficult to effectively prevent harmful arthropods in the prior art is solved, and excellent anti-removal effect is achieved.
Patent Information
- Application Number
- CN202180079146.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2020-09-30
- Filing Date
- 2021-09-29
- Publication Date
- 2025-07-01
- Estimated Expiration
- 2041-09-29
AI Technical Summary
The prior art is difficult to effectively prevent harmful arthropods.
A composition containing a specific heterocyclic compound is provided, the compound or its nitrogen oxide has excellent anti-removal effect.
This compound or its nitrogen oxide can effectively prevent harmful arthropods and provide excellent anti-removal effect.
Smart Images

Figure CN116456817B_ABST
Abstract
Description
Technical Field
[0001] This application claims the priority and benefit of Japanese Patent Application No. 2020-165683 filed on September 30, 2020, the entire content of which is incorporated herein by reference.
[0002] The present invention relates to a heterocyclic compound and a pest control composition containing the heterocyclic compound. Background Art
[0003] Hitherto, various compounds have been studied for the purpose of controlling harmful arthropods. For example, Patent Document 1 describes that a certain compound has a pest control effect.
[0004] Prior Art Documents
[0005] Patent Documents
[0006] Patent Document 1: WO 2016 / 129684 Summary of the Invention
[0007] An object of the present invention is to provide a compound having excellent control efficacy against harmful arthropods.
[0008] The present invention is as follows.
[0009] [1] A compound represented by formula (I) (hereinafter, referred to as the compound of the present invention N) or its N-oxide (hereinafter, the compound represented by formula (I) or its N-oxide is referred to as the compound of the present invention).
[0010]
[0011] [In the formula,
[0012] R 2 represents a C1-C6 alkyl group, a cyclopropyl group, or a cyclopropylmethyl group which may be substituted with one or more halogen atoms,
[0013] n represents 0, 1, or 2,
[0014] G 1 represents a nitrogen atom or CR 3a ,
[0015] G 2 represents a nitrogen atom or CR 3b ,
[0016] G 3 represents a nitrogen atom or CR 3c ,
[0017] G 4 represents a nitrogen atom or CR 3d ,
[0018] R 3a , R 3b , R 3c and R 3d are the same or different, and represent a C1-C6 chain hydrocarbon group which may be substituted by one or more substituents selected from group B, a C3-C7 cycloalkyl group which may be substituted by one or more substituents selected from group E, a phenyl group which may be substituted by one or more substituents selected from group H, a five-membered or six-membered aromatic heterocyclic group which may be substituted by one or more substituents selected from group H, or 12 NR 11 R 12 NR 11a R 12a NR 24 NR 11 R 12 NR 24 OR 11 NR 11 C(O)R 13 NR 24 NR 11 C(O)R 13 NR 11 C(O)OR 14 NR 24 NR 11 C(O)OR 14 NR 11 C(O)NR 31 R 32 NR 24 NR 11 C(O)NR 31 R 32 、N=CHNR 31 R 32 、N=S(O) p R 15 R 16 、C(O)R 13 、C(O)OR 17 、C(O)NR 31 R 32 、C(O)NR 11 S(O)2R 23 , CR 30 =NOR 17 NR 11 CR 24 =NOR 17 、S(O) m R 23 , cyano group, nitro group, hydrogen atom, or halogen atom,
[0019] p represents 0 or 1,
[0020] m represents 0, 1 or 2,
[0021] R 30 represents a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, a halogen atom, OR 35 、NR 36 R 37 、or a hydrogen atom,
[0022] R 35 represents a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms,
[0023] R 17 represents a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, a phenyl group which may be substituted by one or more substituents selected from group D, or a hydrogen atom,
[0024] R 11 、R 24 、R 36 and R 37 are the same or different and represent a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, or a hydrogen atom,
[0025] R 12 represents a C1-C6 chain hydrocarbon group which may be substituted by one or more substituents selected from group F, a C3-C7 cycloalkyl group which may be substituted by one or more substituents selected from group J, a C3-C7 cycloalkenyl group which may be substituted by one or more substituents selected from group J, a phenyl group which may be substituted by one or more substituents selected from group D, a six-membered aromatic heterocyclic group which may be substituted by one or more substituents selected from group D, a hydrogen atom, or S(O)2R 23 ,
[0026] R 23 represents a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, or a phenyl group which may be substituted by one or more substituents selected from group D,
[0027] R 11a and R 12a together with the nitrogen atom to which they are bonded form a three- to seven-membered non-aromatic heterocyclic group which may be substituted by one or more substituents selected from group E,
[0028] R 13represents a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C7 cycloalkyl group that can be substituted by one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group that can be substituted by one or more halogen atoms, a phenyl group that can be substituted by one or more substituents selected from group D, a five- or six-membered aromatic heterocyclic group that can be substituted by one or more substituents selected from group D, or a hydrogen atom,
[0029] R 14 represents a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C7 cycloalkyl group that can be substituted by one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group that can be substituted by one or more halogen atoms, or a phenylC1-C3 alkyl group {the phenyl moiety in the phenylC1-C3 alkyl group can be substituted by one or more substituents selected from group D},
[0030] R 15 and R 16 are the same or different and represent a C1-C6 alkyl group that can be substituted by one or more halogen atoms,
[0031] R 31 represents a C1-C6 alkyl group that can be substituted by one or more halogen atoms, or a hydrogen atom,
[0032] R 32 represents a C1-C6 chain hydrocarbon group that can be substituted by one or more substituents selected from group F, a C3-C7 cycloalkyl group that can be substituted by one or more substituents selected from group J, S(O)2R 23 or a hydrogen atom,
[0033] Q represents the group shown by Q1, the group shown by Q2, the group shown by Q3, the group shown by Q4, or the group shown by Q5,
[0034]
[0035] ● represents the bonding position to the remainder of the molecule,
[0036] Z represents an oxygen atom or a sulfur atom,
[0037] A 2 represents a nitrogen atom or CR 4a ,
[0038] A 3 represents a nitrogen atom or CR 4b ,
[0039] A 4 represents a nitrogen atom or CR 4c ,
[0040] A5 Represents nitrogen atom or CR 4d ,
[0041] A 6 Represents nitrogen atom or CR 4e ,
[0042] A 7 Represents nitrogen atom or CR 4f ,
[0043] A 8 Represents nitrogen atom or CR 4g ,
[0044] A 9 Represents nitrogen atom or CR 4h ,
[0045] A 13 represents an oxygen atom, a sulfur atom, or NR 6 ,
[0046] B 1 , B 2 , B 3 and B 4 The combination of:
[0047] B 1 CR 1 , B 2 is a nitrogen atom or CR 6b , B 3 is a nitrogen atom or CR 6c , B 4 is a nitrogen atom or CR 6d combination of;
[0048] B 1 is a nitrogen atom or CR 6a , B 2 CR 1 , B 3 is a nitrogen atom or CR 6c , B 4 is a nitrogen atom or CR 6d Combination of (excluding B 1 , B 2 , B 3 and B 4 All are CH);
[0049] B 1 is a nitrogen atom or CR 6a , B 2 is a nitrogen atom or CR 6b , B 3 CR 1 , B 4 is a nitrogen atom or CR6d combination (wherein, B is not included) 1 , B 2 , B 3 and B 4 are all CH);
[0050] B 1 is a nitrogen atom or CR 6a , B 2 is a nitrogen atom or CR 6b , B 3 is CR 6c , B 4 is CR 1 combination (wherein, B is not included) 1 , B 2 , B 3 and B 4 are all CH); or
[0051] B 1 is a nitrogen atom or CR 6a , B 2 is CR 6b , B 3 is a nitrogen atom, B 4 is CR 1 combination,
[0052] R 1 represents a C1-C6 chain hydrocarbon group that can be substituted by one or more substituents selected from a cyano group and a halogen atom, a C3-C4 cycloalkyl group that can be substituted by one or more substituents selected from a cyano group and a halogen atom, S(O) k R 8 , OR 8 , a halogen atom, OS(O)2R 8 , or a hydrogen atom,
[0053] R 8 represents a C1-C6 chain hydrocarbon group that can be substituted by one or more substituents selected from a cyano group and a halogen atom, or a C3-C4 cycloalkyl group that can be substituted by one or more substituents selected from a cyano group and a halogen atom,
[0054] k represents 0, 1 or 2,
[0055] R 4a , R 4b , R 4c , R 4d , R 4f , R 4g and R 4h are the same or different and represent a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a nitro group, OR 18 , NR18 R 19 、 a cyano group, an amino group, a halogen atom, or a hydrogen atom,
[0056] R 4e represents a C1-C6 chain hydrocarbon group that may be substituted with one or more halogen atoms, a nitro group, OR 18 、NR 18 R 19 、 a cyano group, an amino group, a halogen atom, a hydroxyl group, or a hydrogen atom,
[0057] R 6a 、R 6b 、R 6c and R 6d are the same or different and represent a C1-C6 chain hydrocarbon group that may be substituted with one or more halogen atoms, a C3-C7 cycloalkyl group that may be substituted with one or more halogen atoms, a C1-C6 alkoxy group that may be substituted with one or more halogen atoms, a halogen atom, or a hydrogen atom, R 18 represents a C1-C6 chain hydrocarbon group that may be substituted with one or more halogen atoms,
[0058] R 19 represents a C1-C6 chain hydrocarbon group that may be substituted with one or more halogen atoms, or a hydrogen atom,
[0059] R 6 represents a C1-C6 chain hydrocarbon group that may be substituted with one or more substituents selected from group F, a C3-C6 cycloalkyl group that may be substituted with one or more substituents selected from group J, a phenyl group that may be substituted with one or more substituents selected from group H, a five- or six-membered aromatic heterocyclic group that may be substituted with one or more substituents selected from group H, or a hydrogen atom.
[0060] Group B: A group consisting of a C1-C6 alkoxy group that may be substituted with one or more halogen atoms, a C3-C6 alkenyloxy group that may be substituted with one or more halogen atoms, a C3-C6 alkynyloxy group that may be substituted with one or more halogen atoms, a C1-C6 alkylthio group that may be substituted with one or more halogen atoms, a C1-C6 alkylsulfinyl group that may be substituted with one or more halogen atoms, a C1-C6 alkylsulfonyl group that may be substituted with one or more halogen atoms, a C3-C6 cycloalkyl group that may be substituted with one or more halogen atoms, a cyano group, a hydroxyl group, and a halogen atom.
[0061] Group C: A group consisting of a C1-C6 chain hydrocarbon group that may be substituted with one or more halogen atoms, a C1-C6 alkoxy group that may be substituted with one or more halogen atoms, a C3-C6 alkenyloxy group that may be substituted with one or more halogen atoms, a C3-C6 alkynyloxy group that may be substituted with one or more halogen atoms, and a halogen atom.
[0062] Group D: a group consisting of a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, a hydroxyl group, a C1-C6 alkoxy group which may be substituted by one or more halogen atoms, a C3-C6 alkenyloxy group which may be substituted by one or more halogen atoms, a C3-C6 alkynyloxy group which may be substituted by one or more halogen atoms, a mercapto group, a C1-C6 alkylthio group which may be substituted by one or more halogen atoms, a C1-C6 alkylsulfinyl group which may be substituted by one or more halogen atoms, a C1-C6 alkylsulfonyl group which may be substituted by one or more halogen atoms, an amino group, NHR 21 、NR 21 R 22 、C(O)R 21 、OC(O)R 21 、C(O)OR 21 、a cyano group, a nitro group, and a halogen atom.
[0063] R 21 and R 22 are the same or different and represent a C1-C6 alkyl group which may be substituted by one or more halogen atoms.
[0064] Group E: a group consisting of a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, a C1-C6 alkoxy group which may be substituted by one or more halogen atoms, a C3-C6 alkenyloxy group which may be substituted by one or more halogen atoms, a C3-C6 alkynyloxy group which may be substituted by one or more halogen atoms, a halogen atom, an oxo group, a hydroxyl group, a cyano group, and a nitro group.
[0065] Group F: a group consisting of a C1-C6 alkoxy group which may be substituted by one or more halogen atoms, a phenyl group which may be substituted by one or more substituents selected from Group D, a five- or six-membered aromatic heterocyclic group which may be substituted by one or more substituents selected from Group D, a C3-C7 cycloalkyl group which may be substituted by one or more halogen atoms, a three- to seven-membered non-aromatic heterocyclic group which may be substituted by one or more substituents selected from Group C, an amino group, NHR 21 、NR 21 R 22 、a halogen atom, and a cyano group.
[0066] Group H: a group consisting of a C1-C6 alkyl group which may be substituted by one or more halogen atoms, a five- or six-membered aromatic heterocyclic group which may be substituted by one or more substituents selected from Group D, OR 10 、NR 9 R 10 、C(O)R 10 、C(O)NR 9 R 10 、OC(O)R 9 、OC(O)OR 9 、NR 10 C(O)R9 、 NR 10 C(O)OR 9 、 C(O)OR 10 、 a group consisting of a halogen atom, a nitro group, a cyano group, and an amino group.
[0067] R 9 represents a C1-C6 alkyl group which may be substituted by one or more halogen atoms, or a C3-C6 cycloalkyl group which may be substituted by one or more halogen atoms,
[0068] R 10 represents a C1-C6 alkyl group which may be substituted by one or more halogen atoms, a C3-C6 cycloalkyl group which may be substituted by one or more halogen atoms, or a hydrogen atom.
[0069] Group J: a group consisting of a C1-C6 alkyl group which may be substituted by one or more halogen atoms, a halogen atom, and a cyano group.
[0070] [2] The compound or its N-oxide according to [1], wherein R 2 is a C1-C6 alkyl group which may be substituted by one or more halogen atoms,
[0071] G 1 is CR 3a ,
[0072] G 2 is CR 3b ,
[0073] G 3 is CR 3c ,
[0074] G 4 is CR 3d ,
[0075] R 3a 、 R 3b 、 R 3c and R 3d are the same or different and are a C1-C6 chain hydrocarbon group which may be substituted by one or more halogen atoms, a C3-C7 cycloalkyl group (the C3-C7 cycloalkyl group may be substituted by one or more substituents selected from a halogen atom and a cyano group), a hydrogen atom, or a halogen atom,
[0076] Q is a group represented by Q2, a group represented by Q3, a group represented by Q4, or a group represented by Q5,
[0077] Z is an oxygen atom,
[0078] A 4 is a nitrogen atom,
[0079] A 5 is CH,
[0080] A 6 is CH,
[0081] A 7 is a nitrogen atom,
[0082] A 8 is CR 4g ,
[0083] B 1 、B 2 、B 3 and B 4 have the following combinations:
[0084] B 1 is a nitrogen atom or CR 6a 、B 2 is CR 1 、B 3 is a nitrogen atom or CR 6c 、B 4 is CR 6d ; or
[0085] B 1 is CR 6a 、B 2 is CR 6b 、B 3 is CR 1 、B 4 is CR 6d ;
[0086] R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom,
[0087] R 6a 、R 6b 、R 6c and R 6d are each a hydrogen atom.
[0088] [3] The compound or its N-oxide according to [2], wherein Q is the group represented by Q2 or the group represented by Q3,
[0089] B 1 、B 2 、B 3 and B 4 have the following combinations:
[0090] B 1 is CR 6a 、B 2 is CR 1 、B 3is CR 6c and B 4 is CR 6d in combination; or
[0091] B 1 is CR 6a and B 2 is CR 6b and B 3 is CR 1 and B 4 is CR 6d in combination,
[0092] R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0093] [4] The compound or its N-oxide according to [2] or [3], wherein R 3a , R 3b , R 3c and R 3d are the same or different and are a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a hydrogen atom, or a halogen atom.
[0094] [5] A harmful arthropod control composition containing the compound or its N-oxide according to any one of [1] to [4].
[0095] [6] A composition containing one or more components selected from group (a), group (b), group (c) and group (d), and the compound or its N-oxide according to any one of [1] to [4]:
[0096] Group (a): A group consisting of an insecticidal active ingredient, a miticidal active ingredient and a nematicidal active ingredient;
[0097] Group (b): A bactericidal active ingredient;
[0098] Group (c): A plant growth regulating ingredient;
[0099] Group (d): A repellent ingredient.
[0100] [7] A method for controlling harmful arthropods, applying an effective amount of the compound or its N-oxide according to any one of [1] to [4], or an effective amount of the composition according to [6] to harmful arthropods or their habitats.
[0101] [8] A seed or vegetative propagation organ that retains an effective amount of the compound or its N-oxide according to any one of [1] to [4], or an effective amount of the composition according to [6].
[0102] According to the present invention, harmful arthropods can be controlled. Detailed Description of the Invention
[0103] The substituents in the present invention will be described.
[0104] The halogen atom means a fluorine atom, a chlorine atom, a bromine atom or an iodine atom.
[0105] When the substituent is substituted with two or more halogen atoms or substituents, these halogen atoms or substituents may be the same or different from each other.
[0106] The description of "CX-CY" in this specification means that the number of carbon atoms is from X to Y. For example, the description of "C1-C6" means that the number of carbon atoms is from 1 to 6.
[0107] The chain hydrocarbon group means an alkyl group, an alkenyl group or an alkynyl group.
[0108] Examples of the alkyl group include a methyl group, an ethyl group, a propyl group, an isopropyl group, a 1,1-dimethylpropyl group, a 1,2-dimethylpropyl group, a 1-ethylpropyl group, a butyl group, a sec-butyl group, a tert-butyl group, a pentyl group and a hexyl group.
[0109] Examples of the alkenyl group include a vinyl group, a 1-propenyl group, a 2-propenyl group, a 1-methyl-1-propenyl group, a 1-methyl-2-propenyl group, a 1,2-dimethyl-1-propenyl group, a 1-ethyl-2-propenyl group, a 3-butenyl group, a 4-pentenyl group and a 5-hexenyl group.
[0110] Examples of the alkynyl group include an ethynyl group, a 1-propynyl group, a 2-propynyl group, a 1-methyl-2-propynyl group, a 1,1-dimethyl-2-propynyl group, a 1-ethyl-2-propynyl group, a 2-butynyl group, a 4-pentynyl group and a 5-hexynyl group.
[0111] Examples of the alkoxy group include a methoxy group, an ethoxy group, a propoxy group, an isopropoxy group, a butoxy group, a tert-butoxy group, a pentyloxy group and a hexyloxy group.
[0112] Examples of the alkenyloxy group include a 2-propenyloxy group, a 2-butenyloxy group and a 5-hexenyloxy group.
[0113] Examples of the alkynyloxy group include a 2-propynyloxy group, a 2-butynyloxy group and a 5-hexynyloxy group.
[0114] Examples of the cycloalkyl group include a cyclopropyl group, a cyclobutyl group, a cyclopentyl group, a cyclohexyl group and a cycloheptyl group.
[0115] Examples of the cycloalkenyl group include a cyclopropenyl group, a cyclobutenyl group, a cyclopentenyl group, a cyclohexenyl group and a cycloheptenyl group.
[0116] A three- to seven-membered non-aromatic heterocyclic group represents an aziridine ring, an azetidine ring, a pyrrolidine ring, an imidazoline ring, an imidazolidine ring, a piperidine ring, a tetrahydropyrimidine ring, a hexahydropyrimidine ring, a piperazine ring, an azepane ring, an oxazolidine ring, an iso oxazolidine ring, a 1,3- oxazine ring, a morpholine ring, a 1,4-oxazepane ring, a thiazolidine ring, an isothiazolidine ring, a 1,3-thiazine ring, a thiomorpholine ring or a 1,4-thiazepane ring.
[0117] Examples of the three- to seven-membered non-aromatic heterocyclic group that may be substituted with one or more substituents selected from Group E include the groups shown below.
[0118]
[0119] A five- or six-membered aromatic heterocyclic group represents a five-membered aromatic heterocyclic group or a six-membered aromatic heterocyclic group. The five-membered aromatic heterocyclic group refers to a pyrrolyl group, a furyl group, a thienyl group, a pyrazolyl group, an imidazolyl group, a triazolyl group, a tetrazolyl group, an oxazolyl group, an iso oxazolyl group, a thiazolyl group, an isothiazolyl group, a dioxazolyl group or a thiadiazolyl group, and the six-membered aromatic heterocyclic group refers to a pyridyl group, a pyridazinyl group, a pyrimidinyl group, a pyrazinyl group, a triazinyl group or a tetrazinyl group.
[0120] Examples of the (C3-C6 cycloalkyl)C1-C3 alkyl that may be substituted with one or more halogen atoms include cyclopropylmethyl, (2-fluorocyclopropyl)methyl, cyclopropyl(fluoro)methyl, and (2-fluorocyclopropyl)(fluoro)methyl.
[0121] Examples of the phenyl C1-C3 alkyl {the phenyl moiety in the phenyl C1-C3 alkyl may be substituted with one or more substituents selected from Group D} include benzyl, 2-fluorobenzyl, 4-chlorobenzyl, 4-(trifluoromethyl)benzyl, and 2-[4-(trifluoromethyl)phenyl]ethyl.
[0122] Examples of the alkylthio group include methylthio, ethylthio, propylthio, and isopropylthio.
[0123] Examples of the alkylsulfinyl group include methylsulfinyl, ethylsulfinyl, propylsulfinyl, and isopropylsulfinyl.
[0124] Examples of the alkylsulfonyl group include methylsulfonyl, ethylsulfonyl, propylsulfonyl, and isopropylsulfonyl.
[0125] Examples of the N-oxide of the compound represented by formula (I) include the compounds represented by the following formula.
[0126]
[0127] [In the formula, R 40 represents any substituent selected from the group H, x represents 0, 1, 2, 3 or 4, y represents 0, 1, 2 or 3, and the other symbols have the same meanings as described above.]
[0128] The compounds of the present invention sometimes have more than one stereoisomer. Examples of stereoisomers include enantiomers, diastereoisomers, and geometric isomers. The compounds of the present invention include each stereoisomer and a mixture of stereoisomers in any ratio.
[0129] The compounds of the present invention sometimes form acid addition salts. Examples of acids for forming acid addition salts include inorganic acids such as hydrogen chloride, phosphoric acid, sulfuric acid, and organic acids such as acetic acid, trifluoroacetic acid, benzoic acid, and p-toluenesulfonic acid. The acid addition salts are obtained by mixing the compounds of the present invention with an acid.
[0130] As the compound N of the present invention, the following compounds can be cited.
[0131] [Mode 1] The compound N of the present invention is G 1 is CR 3a , G 2 is CR 3b , G 3 is CR 3c , G 4 is CR 3d , R 3a , R 3b , R 3c and R 3d are the same or different and are a C1-C6 chain hydrocarbon group that can be substituted with one or more halogen atoms, a C3-C7 cycloalkyl group {the C3-C7 cycloalkyl group can be substituted with one or more substituents selected from halogen atoms and cyano groups}, a halogen atom, or a hydrogen atom.
[0132] [Mode 2] The compound N of the present invention is G 1 is CR 3a , G 2 is CR 3b , G 3 is CR 3c , G 4 is CR 3d , R 3a , R 3b , R 3c and R 3d are the same or different and are a C1-C6 chain hydrocarbon group that can be substituted with one or more halogen atoms, a halogen atom, or a hydrogen atom.
[0133] [Mode 3] Compound N of the present invention is G 1 is CH, G 2 is CR 3b , G 3 is CR 3c , G 4 is CH, R 3b and R 3c are the same or different and are C1-C6 chain hydrocarbon groups which may be substituted by one or more halogen atoms, halogen atoms, or hydrogen atoms.
[0134] [Mode 4] Compound N of the present invention is G 1 is CH, G 2 is CR 3b , G 3 is CR 3c , G 4 is CH, R 3b and R 3c are the same or different and are trifluoromethyl or hydrogen atoms.
[0135] [Mode 5] Compound N of the present invention is R 2 is a compound in which R is a C1-C6 alkyl group.
[0136] [Mode 6] Compound N of the present invention is R 2 is a compound in which R is ethyl.
[0137] [Mode 7] The compound according to Mode 1, wherein R 2 is a C1-C6 alkyl group.
[0138] [Mode 8] The compound according to Mode 2, wherein R 2 is a C1-C6 alkyl group.
[0139] [Mode 9] The compound according to Mode 3, wherein R 2 is a C1-C6 alkyl group.
[0140] [Mode 10] The compound according to Mode 4, wherein R 2 is a C1-C6 alkyl group.
[0141] [Mode 11] The compound according to Mode 1, wherein R 2 is ethyl.
[0142] [Mode 12] The compound according to Mode 2, wherein R 2 is ethyl.
[0143] [Mode 13] The compound according to Mode 3, wherein R 2 is ethyl.
[0144] [Embodiment 14] The compound according to Embodiment 4, wherein R 2 is ethyl.
[0145] [Embodiment 15] Compound N of the present invention is a compound where n is 2.
[0146] [Embodiment 16] The compound according to Embodiment 1, wherein n is 2.
[0147] [Embodiment 17] The compound according to Embodiment 2, wherein n is 2.
[0148] [Embodiment 18] The compound according to Embodiment 3, wherein n is 2.
[0149] [Embodiment 19] The compound according to Embodiment 4, wherein n is 2.
[0150] [Embodiment 20] The compound according to Embodiment 5, wherein n is 2.
[0151] [Embodiment 21] The compound according to Embodiment 6, wherein n is 2.
[0152] [Embodiment 22] The compound according to Embodiment 7, wherein n is 2.
[0153] [Embodiment 23] The compound according to Embodiment 8, wherein n is 2.
[0154] [Embodiment 24] The compound according to Embodiment 9, wherein n is 2.
[0155] [Embodiment 25] The compound according to Embodiment 10, wherein n is 2.
[0156] [Embodiment 26] The compound according to Embodiment 11, wherein n is 2.
[0157] [Embodiment 27] The compound according to Embodiment 12, wherein n is 2.
[0158] [Embodiment 28] The compound according to Embodiment 13, wherein n is 2.
[0159] [Embodiment 29] The compound according to Embodiment 14, wherein n is 2.
[0160] [Embodiment 30] The compound according to any one of Embodiments 1 to 29 or Compound N of the present invention, wherein Q is the group represented by Q2, the group represented by Q3, the group represented by Q4, or the group represented by Q5, Z is an oxygen atom, A 4 is a nitrogen atom, A 5 is CH, A 6 is CH, A 7 is a nitrogen atom, A 8 is CR 4g , B 1For CR 6a ,B 4 For CR 6d ,B 2 And B 3 The combination of and B is as follows: B 2 For CR 1 And B 3 For CR 6c The combination; or B 2 For CR 6b And B 3 For CR 1 The combination.
[0161] [Mode 31] A compound according to any one of Modes 1 to 29 or the compound N of the present invention, wherein Q is a group represented by Q2, a group represented by Q3 or a group represented by Q4, Z is an oxygen atom, A 2 For CR 4a ,A 4 Is a nitrogen atom, A 5 Is CH, A 6 Is CH, A 7 Is a nitrogen atom, A 13 Is an oxygen atom, B 1 For CR 6a ,B 4 For CR 6d ,B 2 And B 3 The combination of and B is as follows: B 2 For CR 1 And B 3 For CR 6c The combination; or B 2 For CR 6b And B 3 For CR 1 The combination.
[0162] [Mode 32] A compound according to any one of Modes 1 to 29 or the compound N of the present invention, wherein Q is a group represented by Q2, a group represented by Q3 or a group represented by Q4, Z is an oxygen atom, A 2 Is CH, A 4 Is a nitrogen atom, A 5 Is CH, A 6 Is CH, A 7 Is a nitrogen atom, A 13 Is an oxygen atom, B 1 For CR 6a ,B 4 For CR 6d ,B 2 And B 3 The combination of and B is as follows: B 2 For CR 1 And B3 is a combination of CR 6c ; or B 2 is a combination of CR 6b and B 3 is a combination of CR 1 .
[0163] [Mode 33] A compound according to any one of Modes 1 to 29 or the compound N of the present invention, wherein Q is the group represented by Q2, Z is an oxygen atom, A 4 is a nitrogen atom, A 5 is CH, B 1 is a combination of CR 6a , B 4 is a combination of CR 6d , B 2 and B 3 are combined as follows: B 2 is a combination of CR 1 and B 3 is a combination of CR 6c ; or B 2 is a combination of CR 6b and B 3 is a combination of CR 1 .
[0164] [Mode 34] A compound according to any one of Modes 1 to 29 or the compound N of the present invention, wherein Q is the group represented by Q3, Z is an oxygen atom, A 6 is CH, A 7 is a nitrogen atom, B 1 is a combination of CR 6a , B 4 is a combination of CR 6d , B 2 and B 3 are combined as follows: B 2 is a combination of CR 1 and B 3 is a combination of CR 6c ; or B 2 is a combination of CR 6b and B 3 is a combination of CR 1 .
[0165] [Mode 35] The compound N of the present invention is B 1 is a combination of CR 6a , B 4 is a combination of CR 6d , B 2 and B 3 are combined as follows: B 2 is a combination of CR 1 and B 3 is a combination of CR 6c ; or B2 is CR 6b and B 3 is CR 1 a compound of the combination of
[0166] [Mode 36] Compound N of the present invention is R 1 a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0167] [Mode 37] Compound N of the present invention is R 1 a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom compound
[0168] [Mode 38] Compound N of the present invention is R 1 a compound that is trifluoromethyl or a halogen atom
[0169] [Mode 39] The compound according to Mode 30, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0170] [Mode 40] The compound according to Mode 31, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0171] [Mode 41] The compound according to Mode 32, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0172] [Mode 42] The compound according to Mode 33, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0173] [Mode 43] The compound according to Mode 34, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom
[0174] [Mode 44] The compound according to Mode 35, wherein R 1is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, a C3-C4 cycloalkyl group that can be substituted by one or more halogen atoms, or a halogen atom.
[0175] [Mode 45] The compound according to Mode 30, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0176] [Mode 46] The compound according to Mode 31, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0177] [Mode 47] The compound according to Mode 32, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0178] [Mode 48] The compound according to Mode 33, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0179] [Mode 49] The compound according to Mode 34, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0180] [Mode 50] The compound according to Mode 35, wherein R 1 is a C1-C6 chain hydrocarbon group that can be substituted by one or more halogen atoms, or a halogen atom.
[0181] [Mode 51] The compound according to Mode 30, wherein R 1 is trifluoromethyl or a halogen atom.
[0182] [Mode 52] The compound according to Mode 31, wherein R 1 is trifluoromethyl or a halogen atom.
[0183] [Mode 53] The compound according to Mode 32, wherein R 1 is trifluoromethyl or a halogen atom.
[0184] [Mode 54] The compound according to Mode 33, wherein R 1 is trifluoromethyl or a halogen atom.
[0185] [Mode 55] The compound according to Mode 34, wherein R 1 is trifluoromethyl or a halogen atom.
[0186] [Mode 56] The compound according to Mode 35, wherein R 1 is trifluoromethyl or a halogen atom.
[0187] [Mode 57] The compound according to Mode 36, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0188] [Mode 58] The compound according to Mode 37, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0189] [Mode 59] The compound according to Mode 38, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0190] [Mode 60] The compound according to Mode 39, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0191] [Mode 61] The compound according to Mode 40, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0192] [Mode 62] The compound according to Mode 41, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0193] [Mode 63] The compound according to Mode 42, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0194] [Mode 64] The compound according to Mode 43, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0195] [Mode 65] The compound according to Mode 44, wherein R 6a, R 6b , R 6c and R 6d are each a hydrogen atom.
[0196] [Mode 66] A compound according to Mode 45, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0197] [Mode 67] A compound according to Mode 46, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0198] [Mode 68] A compound according to Mode 47, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0199] [Mode 69] A compound according to Mode 48, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0200] [Mode 70] A compound according to Mode 49, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0201] [Mode 71] A compound according to Mode 50, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0202] [Mode 72] A compound according to Mode 51, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0203] [Mode 73] A compound according to Mode 52, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0204] [Mode 74] A compound according to Mode 53, wherein R6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0205] [Embodiment 75] The compound according to Embodiment 54, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0206] [Embodiment 76] The compound according to Embodiment 55, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0207] [Embodiment 77] The compound according to Embodiment 56, wherein R 6a , R 6b , R 6c and R 6d are each a hydrogen atom.
[0208] [Embodiment 78] The compound N of the present invention is such that G 1 is CH, G 2 is CR 3b , G 3 is CR 3c , G 4 is CH, R 3b and R 3c are the same or different and are a trifluoromethyl group, a halogen atom, or a hydrogen atom, R 2 is an ethyl group, n is 2, Q is a group represented by Q2, a group represented by Q3, or a group represented by Q4, Z is an oxygen atom, A 2 is CH, A 4 is a nitrogen atom, A 5 is CH, A 6 is CH, A 7 is a nitrogen atom, A 13 is an oxygen atom, B 1 is CH, B 4 is CH, B 2 and B 3 in combination are such that B 2 is CR 1 and B 3 is CH combination or B 2 is CH and B 3 is CR 1 combination, R 1 is a compound of a trifluoromethyl group or a halogen atom.
[0209] [Embodiment 79] The compound N of the present invention is such that G1 is CH, G 2 is CR 3b , G 3 is CR 3c , G 4 is CH, R 3b and R 3c are the same or different and are trifluoromethyl or a hydrogen atom, R 2 is ethyl, n is 2, Q is the group represented by Q2, the group represented by Q3 or the group represented by Q4, Z is an oxygen atom, A 2 is CH, A 4 is a nitrogen atom, A 5 is CH, A 6 is CH, A 7 is a nitrogen atom, A 13 is an oxygen atom, B 1 is CH, B 4 is CH, B 2 and B 3 The combination of is B 2 is CR 1 and B 3 The combination of is CH or B 2 is CH and B 3 is CR 1 of, R 1 A compound that is trifluoromethyl or a halogen atom.
[0210] Next, the manufacturing method of the compound of the present invention will be described.
[0211] Manufacturing method 1
[0212] The compound represented by formula (I-b) (hereinafter, referred to as compound (I-b)) or the compound represented by formula (I-c) (hereinafter, referred to as compound (I-c)) can be produced by reacting the compound represented by formula (I-a) (hereinafter, referred to as compound (I-a)) with an oxidizing agent.
[0213]
[0214] [In the formula, the symbols represent the same meanings as described above.]
[0215] First, the method for producing compound (I-b) from compound (I-a) will be described.
[0216] The reaction is usually carried out in a solvent. As the solvent, for example, tetrahydrofuran, 1,4-di Alkanes, ethers such as 1,2 - dimethoxyethane, methyl tert - butyl ether, diethyl ether (hereinafter referred to as ether compounds); halogenated hydrocarbons such as dichloromethane, chloroform (hereinafter referred to as halogenated hydrocarbon compounds); nitriles such as acetonitrile (hereinafter referred to as nitrile compounds); acetic acid; water; and mixtures of two or more thereof.
[0217] As the oxidizing agent, for example, sodium periodate, meta - chloroperoxybenzoic acid (hereinafter referred to as mCPBA), and hydrogen peroxide can be cited.
[0218] When hydrogen peroxide is used as the oxidizing agent, a base or a catalyst can be added as needed.
[0219] As the base, sodium carbonate can be cited. When a base is used in the reaction, relative to 1 mole of compound (I - a), the base is usually used in a proportion of 0.01 - 1 mole.
[0220] As the catalyst, for example, tungstic acid and sodium tungstate can be cited. When a catalyst is used in the reaction, relative to 1 mole of compound (I - a), the catalyst is usually used in a proportion of 0.01 - 0.5 mole.
[0221] In the reaction, relative to 1 mole of compound (I - a), the oxidizing agent is usually used in a proportion of 1 - 1.2 moles.
[0222] The reaction temperature is usually in the range of - 20 to 80°C. The reaction time is usually in the range of 0.1 to 12 hours.
[0223] After the reaction is completed, water is added to the reaction mixture, and extraction is carried out with an organic solvent. The organic layer is washed, if necessary, with an aqueous solution of a reducing agent (such as sodium sulfite, sodium thiosulfate) and an aqueous solution of a base (such as sodium bicarbonate). The organic layer is dried and concentrated, whereby compound (I - b) can be obtained.
[0224] Next, a method for producing compound (I - c) from compound (I - b) is described.
[0225] The reaction is usually carried out in a solvent. As the solvent, for example, halogenated hydrocarbon compounds; nitrile compounds; alcohols such as methanol, ethanol (hereinafter referred to as alcohol compounds); acetic acid; water; and mixtures of two or more thereof can be cited.
[0226] As the oxidizing agent, for example, mCPBA and hydrogen peroxide can be cited.
[0227] In the reaction, relative to 1 mole of compound (I - b), the oxidizing agent is usually used in a proportion of 1 - 2 moles.
[0228] When hydrogen peroxide is used as the oxidizing agent, a base or a catalyst can be used as needed.
[0229] As the base, sodium carbonate can be mentioned. When using a base in the reaction, relative to 1 mole of the compound (I-b), the base is usually used in a proportion of 0.01 to 1 mole.
[0230] As the catalyst, for example, sodium tungstate can be mentioned. When using a catalyst in the reaction, relative to 1 mole of the compound (I-b), the catalyst is usually used in a proportion of 0.01 to 0.5 mole.
[0231] The reaction temperature is usually in the range of -20 to 120 °C. The reaction time is usually in the range of 0.1 to 12 hours.
[0232] After the reaction is completed, water is added to the reaction mixture, extraction is carried out with an organic solvent, and the organic layer is washed with an aqueous solution of a reducing agent (such as sodium sulfite, sodium thiosulfate) and an aqueous solution of a base (such as sodium bicarbonate) as needed. The obtained organic layer is dried and concentrated, whereby the compound (I-c) can be obtained.
[0233] In addition, the compound (I-c) can also be produced by reacting the compound (I-a) with an oxidizing agent using a one-step reaction (one-pot method).
[0234] The reaction is usually carried out using an oxidizing agent in a proportion of 2 to 5 moles relative to 1 mole of the compound (I-a) and according to the method for producing the compound (I-c) from the compound (I-b).
[0235] Production Method 2
[0236] The compound represented by the formula (I-Q1-2) (hereinafter, referred to as the compound (I-Q1-2)) can be produced by reacting the compound represented by the formula (I-Q1-1) (hereinafter, referred to as the compound (I-Q1-1)) with a sulfurizing agent.
[0237]
[0238] [In the formula, the symbols have the same meanings as described above.]
[0239] The reaction is carried out in the presence or absence of a solvent. As the solvent, for example, ethers, halogenated hydrocarbons; aromatic hydrocarbons such as toluene and xylene (hereinafter, referred to as aromatic hydrocarbons); nitriles; and mixtures of two or more of them can be mentioned.
[0240] As the sulfurizing agent, phosphorus pentasulfide, Lawesson's reagent (2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide), etc. can be mentioned.
[0241] In the reaction, relative to 1 mole of the compound (I-Q1-1), the sulfurizing agent is usually used in a proportion of 1 to 3 moles.
[0242] The reaction temperature is generally in the range of 0 to 200 °C. The reaction time is generally in the range of 1 to 24 hours.
[0243] After completion of the reaction, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (I-Q1-2) can be obtained.
[0244] Production method 3
[0245] The compound represented by the formula (I-Q2-2) (hereinafter referred to as compound (I-Q2-2)) can be produced by reacting the compound represented by the formula (I-Q2-1) (hereinafter referred to as compound (I-Q2-1)) with a sulfurizing agent.
[0246]
[0247] [In the formula, the symbols represent the same meanings as described above.]
[0248] The reaction can be carried out according to Production method 2.
[0249] Production method 4
[0250] The compound represented by the formula (I-Q3-2) (hereinafter referred to as compound (I-Q3-2)) can be produced by reacting the compound represented by the formula (I-Q3-1) (hereinafter referred to as compound (I-Q3-1)) with a sulfurizing agent.
[0251]
[0252] [In the formula, the symbols represent the same meanings as described above.]
[0253] The reaction can be carried out according to Production method 2.
[0254] Production method 5
[0255] The compound represented by the formula (I-Q4-2) (hereinafter referred to as compound (I-Q4-2)) can be produced by reacting the compound represented by the formula (I-Q4-1) (hereinafter referred to as compound (I-Q4-1)) with a sulfurizing agent.
[0256]
[0257] [In the formula, the symbols represent the same meanings as described above.]
[0258] The reaction can be carried out according to Production method 2.
[0259] Production method 6
[0260] The compound represented by formula (I-Q5-2) (hereinafter referred to as compound (I-Q5-2)) can be produced by reacting the compound represented by formula (I-Q5-1) (hereinafter referred to as compound (I-Q5-1)) with a sulfurizing agent.
[0261]
[0262] [In the formula, the symbols have the same meanings as described above.]
[0263] The reaction can be carried out according to Production Method 2.
[0264] Production Method 7
[0265] The compound represented by formula (II-Q3-1) (hereinafter referred to as compound (II-Q3-1)) can be produced by reacting the compound represented by formula (M-Q3-1) (hereinafter referred to as compound (M-Q3-1)) with the compound represented by formula (R-1) (hereinafter referred to as compound (R-1)).
[0266]
[0267] [In the formula, R 41 represents methoxy, ethoxy, dimethylamino or hydroxy, R 42 represents methyl or ethyl, and the other symbols have the same meanings as described above.]
[0268] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include aprotic polar solvents (hereinafter referred to as aprotic polar solvent classes) such as N-methylpyrrolidone (hereinafter referred to as NMP), N,N-dimethylformamide (hereinafter referred to as DMF), dimethyl sulfoxide (hereinafter referred to as DMSO); alcohols; ethers; halogenated hydrocarbons; aromatic hydrocarbons; nitriles; water and mixtures of two or more of them.
[0269] The reaction can use a base as needed. Examples of the base used in the reaction include organic bases (hereinafter referred to as organic base classes) such as triethylamine, diisopropylethylamine, pyridine, 4-(dimethylamino)pyridine; and alkali metal carbonates (hereinafter referred to as alkali metal carbonate classes) such as sodium carbonate and potassium carbonate. When a base is used in the reaction, it is usually used in a proportion of 0.1 to 5 moles relative to 1 mole of compound (M-Q3-1).
[0270] In the reaction, compound (R-1) is usually used in a proportion of 1 to 10 moles relative to 1 mole of compound (M-Q3-1).
[0271] The reaction temperature is usually in the range of -20°C to 200°C. The reaction time is usually in the range of 0.1 to 48 hours.
[0272] After completion of the reaction, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (II-Q3-1) can be obtained.
[0273] The compound (R-1) is a commercially available compound or can be produced by a known method.
[0274] Production method 8
[0275] The compound represented by the formula (II-Q2-1) (hereinafter referred to as compound (II-Q2-1)) can be produced by cyclizing the compound represented by the formula (M-Q2-1) (hereinafter referred to as compound (M-Q2-1)).
[0276]
[0277] [In the formula, the symbols have the same meanings as described above.]
[0278] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include ethers, aromatic hydrocarbons, nitriles, halogenated hydrocarbons, aprotic polar solvents, alcohols, water, and mixtures of two or more thereof.
[0279] The reaction can use an acid as needed. Examples of the acid used in the reaction include organic acids such as formic acid, acetic acid, propionic acid, trifluoroacetic acid, p-toluenesulfonic acid, trifluoromethanesulfonic acid (hereinafter referred to as organic acid classes); and inorganic acids such as hydrochloric acid and sulfuric acid (hereinafter referred to as inorganic acid classes). When an acid is used in the reaction, the acid is usually used in a ratio of 0.1 to 5 moles relative to 1 mole of the compound (M-Q2-1).
[0280] When an acid is used, the reaction temperature is usually in the range of -20°C to 150°C, and the reaction time is usually in the range of 0.1 to 48 hours. When no acid is used, the reaction temperature is in the range of 20 to 150°C, and the reaction time is usually in the range of 0.5 to 48 hours.
[0281] After completion of the reaction, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (II-Q2-1) can be obtained.
[0282] Production method 9
[0283] The compound represented by the formula (I-Qa) (hereinafter referred to as compound (I-Qa)) can be produced according to the following scheme.
[0284]
[0285] [In the formula, X a represents a chlorine atom, a bromine atom, or an iodine atom, R44 represents SR 2 or a hydrogen atom, Qa represents the group represented by Q1a, the group represented by Q2a, the group represented by Q3a, the group represented by Q4a, or the group represented by Q5a, and other symbols represent the same meanings as described above.
[0286] First, the process for producing the compound represented by formula (M-I-1) (hereinafter referred to as compound (M-I-1)) from the compound represented by formula (M-I-2) (hereinafter referred to as compound (M-I-2)) will be described.
[0287] Compound (M-I-1) can be produced by reacting compound (M-I-2) with a halogenating agent.
[0288] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include alcohols, nitriles, ethers, aromatic hydrocarbons, aprotic polar solvents, halogenated hydrocarbons, water, and mixtures of two or more of them.
[0289] Examples of the halogenating agent include chlorine, bromine, iodine, N-chlorosuccinimide, N-bromosuccinimide, N-iodosuccinimide (hereinafter referred to as NIS), etc.
[0290] In the reaction, relative to 1 mole of compound (M-I-2), the halogenating agent is usually used in a ratio of 1 to 20 moles.
[0291] The reaction temperature is usually in the range of -20°C to 200°C. The reaction time is usually in the range of 0.1 to 72 hours.
[0292] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby compound (M-I-1) can be obtained.
[0293] Next, the process for producing compound (I-Qa) from compound (M-I-1) will be described.
[0294] Compound (I-Qa) can be produced by reacting compound (M-I-1) with the compound represented by formula (R-2) (hereinafter referred to as compound (R-2)) in the presence of a metal catalyst and a base.
[0295] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include alcohols, nitriles, ethers, aromatic hydrocarbons, aprotic polar solvents, water, and mixtures of two or more of them.
[0296] As the metal catalyst used in the reaction, for example, palladium catalysts such as tetrakis(triphenylphosphine)palladium(0), dichlorobis(1,1'-bis(diphenylphosphino)ferrocene)palladium(II), tris(dibenzylideneacetone)dipalladium(0) (hereinafter referred to as Pd2(dba)3), palladium(II) acetate, etc.; nickel catalysts such as bis(cyclooctadiene)nickel(0), nickel(II) chloride, etc.; and copper catalysts such as copper(I) iodide, copper(I) chloride, etc.
[0297] As the base used in the reaction, for example, alkali metal hydrides such as sodium hydride (hereinafter referred to as alkali metal hydride type); alkali metal carbonates; and organic bases can be cited.
[0298] A ligand can also be used in the reaction. As the ligand, triphenylphosphine, Xantphos, 2,2'-bis(diphenylphosphino)-1,1'-binaphthalene, 1,1'-bis(diphenylphosphino)ferrocene, 2-dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl, 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl, 1,2-bis(diphenylphosphino)ethane, 2,2'-bipyridine, 2-aminoethanol, 8-hydroxyquinoline, 1,10-phenanthroline, etc. can be cited. When a ligand is used in the reaction, the ligand is usually used in a ratio of 0.01 to 1 mole relative to 1 mole of the compound (M-I-1).
[0299] In the reaction, relative to 1 mole of the compound (M-I-1), the compound (R-2) is usually used in a ratio of 1 to 20 moles, the metal catalyst is usually used in a ratio of 0.01 to 0.5 moles, and the base is usually used in a ratio of 0.1 to 5 moles.
[0300] The reaction temperature is usually in the range of -20°C to 200°C. The reaction time is usually in the range of 0.1 to 72 hours.
[0301] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (I-Qa) can be obtained.
[0302] Next, the process for producing the compound (I-Qa) from the compound (M-I-2) will be described.
[0303] The compound (I-Qa) can also be produced by reacting the compound (M-I-2) with the compound represented by the formula (R-3) (hereinafter referred to as the compound (R-3)) in the presence of a halogenating agent.
[0304] The reaction is usually carried out in a solvent. As the solvent used in the reaction, for example, alcohols, nitriles, ethers, aromatic hydrocarbons, aprotic polar solvents, water, and mixtures of two or more of them can be cited.
[0305] As the halogenating agent, bromine, iodine, sodium bromide, potassium bromide, sodium iodide, potassium iodide, etc. can be mentioned.
[0306] An oxidizing agent can be used as needed in the reaction. As the oxidizing agent, hydrogen peroxide, tert-butyl hydroperoxide, and DMSO can be mentioned. When an oxidizing agent is used in the reaction, relative to 1 mol of the compound (M-I-2), the oxidizing agent is usually used in a proportion of 1 to 20 mol.
[0307] In the reaction, relative to 1 mol of the compound (M-I-2), the compound (R-3) is usually used in a proportion of 0.5 to 10 mol, and the halogenating agent is usually used in a proportion of 0.05 to 10 mol.
[0308] The reaction temperature is usually in the range of 0°C to 200°C. The reaction time is usually in the range of 0.1 to 72 hours.
[0309] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (I-Qa) can be obtained.
[0310] The compounds (R-2) and (R-3) are publicly known or can be manufactured according to publicly known methods.
[0311] Production Method 10
[0312] The compound (I-Q5-1) can be produced by reacting the compound represented by the formula (M-Q5-1) (hereinafter referred to as the compound (M-Q5-1)) with the compound represented by the formula (M-Q5-2) (hereinafter referred to as the compound (M-Q5-2)) in the presence of a base.
[0313]
[0314] [In the formula, the symbols represent the same meanings as described above.]
[0315] The reaction is usually carried out in a solvent. As the solvent used in the reaction, for example, ethers, aromatic hydrocarbons, nitriles, aprotic polar solvents, halogenated hydrocarbons, alcohols, and mixtures of two or more of them can be mentioned.
[0316] As the base used in the reaction, for example, alkali metal carbonates and alkali metal hydrides can be mentioned.
[0317] In the reaction, relative to 1 mol of the compound (M-Q5-1), the compound (M-Q5-2) is usually used in a proportion of 1 to 2 mol, and the base is usually used in a proportion of 1 to 10 mol.
[0318] The reaction temperature is usually in the range of -20°C to 150°C. The reaction time is usually in the range of 0.5 to 24 hours.
[0319] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby compound (I-Q5-1) can be obtained.
[0320] Compound (M-Q5-2) is publicly known, or can be implemented according to publicly known methods (for example, the methods described in Org. Biomol. Chem., 2018, 16, 7050., Org. Lett., 2004, 6, 2433., or Science of Synthesis 2005, 15, 947.).
[0321] Production Method 11
[0322] The compound represented by formula (II-Q4-1) (hereinafter referred to as compound (II-Q4-1)) can be produced by reacting the compound represented by formula (M-Q4-1) (hereinafter referred to as compound (M-Q4-1)) with the compound represented by formula (R-4) (hereinafter referred to as compound (R-4)) in the presence of an acid or a base.
[0323]
[0324] [In the formula, the symbols represent the same meanings as described above.]
[0325] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include ethers, aromatic hydrocarbons, nitriles, aprotic polar solvents, halogenated hydrocarbons, and mixtures of two or more of them.
[0326] Examples of the base used in the reaction include organic bases, alkali metal carbonates, and alkali metal hydrides.
[0327] Examples of the acid used in the reaction include organic acids and inorganic acids.
[0328] In the reaction, relative to 1 mole of compound (M-Q4-1), compound (R-4) is usually used in a ratio of 1 to 10 moles, and the base or acid is usually used in a ratio of 1 to 10 moles.
[0329] The reaction temperature is usually in the range of -20°C to 150°C. The reaction time is usually in the range of 0.5 to 24 hours.
[0330] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby compound (II-Q4-1) can be obtained.
[0331] Production Method 12
[0332] The N-oxide of the compound represented by formula (I) can be produced by reacting the compound represented by formula (I) with an oxidizing agent. The reaction can be carried out, for example, according to the method described in Production Method 1, U.S. Patent Application Publication No. 2018 / 0009778, or International Publication No. 2016 / 121970.
[0333] The production methods of the intermediates are described below.
[0334] Reference Production Method 1
[0335] The compound (M-Q2-1) can be produced from the compound represented by formula (M-Q2-2) (hereinafter referred to as the compound (M-Q2-2)).
[0336]
[0337] [In the formula, the symbols have the same meanings as described above.]
[0338] The reaction can be carried out, for example, according to the method described in Chem. Med. Chem., 2018, 13, 988., Org. Lett., 2016, 18, 6344., or Tetrahedron, 2017, 73, 3939..
[0339] Reference Production Method 2
[0340] The compound (M-Q2-2) can be produced by reacting the compound represented by formula (M-Q2-3) (hereinafter referred to as the compound (M-Q2-3)) with the compound (R-1).
[0341]
[0342] [In the formula, the symbols have the same meanings as described above.]
[0343] The reaction can be carried out, for example, according to the method described in Bioorganic & Medicinal Chemistry Letters, 2015, 25, 4793., European Journal of Medicinal Chemistry, 2016, 122, 178., or Tetrahedron Lett. 1975, 16, 1219..
[0344] The compound (M-Q2-3) is known, or can be prepared according to known methods (for example, the methods described in Journal of Medicinal Chemistry, 2019, 62, 2798. or International Publication No. 2019 / 178129).
[0345] Reference Production Method 3
[0346] The compound (M-Q3-1) can be produced from the compound (M-Q4-1).
[0347]
[0348] [In the formula, the symbols have the same meanings as described above.]
[0349] The reaction can be carried out according to Reference Production Method 1.
[0350] Reference Production Method 4
[0351] The compound represented by the formula (M-Q4-1b) and the compound represented by the formula (M-Q4-1c) can be produced by reacting the compound represented by the formula (M-Q4-1a) (hereinafter, referred to as the compound (M-Q4-1a)) with an oxidizing agent. In addition, the compound represented by the formula (M-Q4-1c) can also be produced by reacting the compound represented by the formula (M-Q4-1b) with an oxidizing agent.
[0352]
[0353] [In the formula, the symbols have the same meanings as described above.]
[0354] These reactions can be carried out according to Production Method 1.
[0355] Reference Production Method 5
[0356] The compound (M-Q4-1a) can be produced according to the following scheme.
[0357]
[0358] [In the formula, the symbols have the same meanings as described above.]
[0359] These reactions can be carried out according to Production Method 9.
[0360] The compound represented by the formula (M-Q4-2) is known or can be produced according to a known method (for example, the method described in Bioorganic & Medicinal Chemistry, 2008, 16(6), 3125.).
[0361] Reference Production Method 6
[0362] The compound represented by the formula (M2-Q5-1) and the compound represented by the formula (M2-Q5-2) can be produced by reacting the compound represented by the formula (M2-Q5-3) with an oxidizing agent. In addition, the compound represented by the formula (M2-Q5-1) can also be produced by reacting the compound represented by the formula (M2-Q5-2) with an oxidizing agent.
[0363]
[0364] [In the formula, X d represents a fluorine atom or a chlorine atom, and other symbols represent the same meanings as described above.]
[0365] These reactions can be carried out according to Production Method 1.
[0366] Refer to Production Method 7
[0367] The compound represented by formula (M2-Q5-4) (hereinafter referred to as compound (M2-Q5-4)) can be produced according to the following scheme.
[0368]
[0369] [In the formula, the symbols represent the same meanings as described above.]
[0370] These reactions can be carried out according to Production Method 9.
[0371] Refer to Production Method 8
[0372] The compound represented by formula (M2-Q5-6) (hereinafter referred to as compound (M2-Q5-6)) can be produced according to the following scheme.
[0373]
[0374] [In the formula, the symbols represent the same meanings as described above.]
[0375] The compound represented by formula (M2-Q5-7) (hereinafter referred to as compound (M2-Q5-7)) can be produced by reacting the compound represented by formula (R-5) (hereinafter referred to as compound (R-5)) with the compound represented by formula (M2-Q5-8) (hereinafter referred to as compound (M2-Q5-8)).
[0376] The reaction is usually carried out in a solvent. Examples of the solvent include ethers, halogenated hydrocarbons, aromatic hydrocarbons, aprotic polar solvents, alcohols, nitriles, and mixtures of two or more of them.
[0377] In the reaction, relative to 1 mole of the compound (M2-Q5-8), the compound (R-5) is usually used in a ratio of 1 to 10 moles.
[0378] The reaction temperature is usually in the range of 0°C to 200°C. The reaction time is usually in the range of 0.1 to 48 hours.
[0379] After completion of the reaction, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (M2-Q5-7) can be obtained.
[0380] Compound (R-5) and compound (M2-Q5-8) are commercially available compounds or can be produced by known methods.
[0381] Compound (M2-Q5-6) can be produced by reacting compound (M2-Q5-7) with phosphorus oxychloride.
[0382] The reaction is usually carried out in a solvent. Examples of the solvent include aromatic hydrocarbons, nitriles, and mixtures of two or more thereof.
[0383] In the reaction, relative to 1 mole of compound (M2-Q5-7), phosphorus oxychloride is usually used in a ratio of 1 to 10 moles.
[0384] The reaction temperature is usually in the range of 60°C to 120°C. The reaction time is usually in the range of 0.1 to 48 hours.
[0385] After completion of the reaction, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby the compound (M2-Q5-6) can be obtained.
[0386] Reference Production Method 9
[0387] Compound (M-Q5-1) can be produced by reacting the compound represented by formula (M-Q5-3) (hereinafter referred to as compound (M-Q5-3)) with cesium fluoride.
[0388]
[0389] [In the formula, the symbols have the same meanings as described above.]
[0390] The reaction can be carried out, for example, according to the method described in Tetrahedron Lett., 2015, 56, 6043.
[0391] Reference Production Method 10
[0392] The compound represented by formula (M2-Q5-9) (hereinafter referred to as compound (M2-Q5-9)) can be produced by reacting compound (M2-Q5-6) with cesium fluoride.
[0393]
[0394] [In the formula, the symbols have the same meanings as described above.]
[0395] The reaction can be carried out according to Reference Production Method 9.
[0396] Reference Production Method 11
[0397] The compound represented by formula (M2-Q5-10) (hereinafter referred to as compound (M2-Q5-10)) can be produced by reacting compound (M2-Q5-9) with compound (M-Q5-2) in the presence of a base.
[0398]
[0399] [In the formula, the symbols have the same meanings as described above.]
[0400] The reaction can be carried out according to Production Method 10.
[0401] Reference Production Method 12
[0402] Compound (M-I-2) can be produced by reacting the compound represented by formula (M-I-3) (hereinafter referred to as compound (M-I-3)) with compound (R-5).
[0403]
[0404] [In the formula, the symbols have the same meanings as described above.]
[0405] The reaction is usually carried out in a solvent. Examples of the solvent used in the reaction include ethers, aromatic hydrocarbons, aprotic polar solvents, halogenated hydrocarbons, alcohols, nitriles, water, and mixtures of two or more of them.
[0406] A base can be used as needed in the reaction. Examples of the base used in the reaction include organic bases and alkali metal carbonates. When a base is used in the reaction, the base is usually used in a ratio of 0.1 to 5 moles relative to 1 mole of compound (M-I-3).
[0407] In the reaction, compound (R-5) is usually used in a ratio of 1 to 10 moles relative to 1 mole of compound (M-I-3).
[0408] The reaction temperature is usually in the range of -20°C to 200°C. The reaction time is usually in the range of 0.1 to 48 hours.
[0409] After the reaction is completed, post-treatment operations such as adding water to the reaction mixture, extracting with an organic solvent, drying the organic layer, and concentrating are carried out, whereby compound (M-I-2) can be obtained.
[0410] Reference Production Method 13
[0411] The compound represented by formula (M-Q1-1) (hereinafter referred to as compound (M-Q1-1)) can be manufactured according to the following scheme.
[0412]
[0413] [In the formula, X c represents a bromine atom or an iodine atom, and the other symbols represent the same meanings as described above.]
[0414] The compound represented by formula (M-Q1-4) (hereinafter referred to as compound (M-Q1-4)) can be manufactured by reacting the compound represented by formula (M-Q1-5) (hereinafter referred to as compound (M-Q1-5)) with a halogenating agent. The reaction can be carried out, for example, according to the methods described in International Publication No. 2012 / 020780 or Chem. Commun., 2015, 51, 17744.
[0415] Compound (M-Q1-5) is publicly known or can be manufactured according to publicly known methods (for example, the methods described in Molecules 2020, 25, 268. or Tetrahedron Letters, 2016, 572488-2491).
[0416] The compound represented by formula (M-Q1-3) (hereinafter referred to as compound (M-Q1-3)) can be manufactured by reacting compound (M-Q1-4) with the compound represented by formula (R-6) (hereinafter referred to as compound (R-6)). The reaction can be carried out, for example, according to the method described in International Publication No. 2016 / 123253.
[0417] Compound (R-6) is publicly known or can be manufactured according to publicly known methods.
[0418] The compound represented by formula (M-Q1-2) (hereinafter referred to as compound (M-Q1-2)) can be manufactured by reacting compound (M-Q1-3) with an acid. The reaction can be carried out, for example, according to the method described in International Publication No. 2016 / 123253.
[0419] Compound (M-Q1-1) can be manufactured by reacting compound (M-Q1-2) with a halogenating agent. The reaction can be carried out according to the method described in International Publication No. 2013 / 191113.
[0420] Reference Manufacturing Method 14
[0421] The compound represented by formula (M2-Q2-1) can be manufactured according to the following scheme.
[0422]
[0423] [In the formula, the symbols represent the same meanings as described above.]
[0424] These reactions can be carried out in accordance with Reference Production Method 13.
[0425] The compound represented by formula (M2-Q2-5) is publicly known or can be produced according to publicly known methods (for example, the methods described in Synthetic Communications 2018, 48, 375., Journal of Medicinal Chemistry 2016, 59, 6070., or Tetrahedron Letters 2014, 55, 1715.).
[0426] Reference Production Method 15
[0427] The compound represented by formula (M2-Q3-1) can be produced according to the following scheme.
[0428]
[0429] [In the formula, the symbols represent the same meanings as described above.]
[0430] These reactions can be carried out in accordance with Reference Production Method 13.
[0431] The compound represented by formula (M2-Q3-5) is publicly known or can be produced according to publicly known methods (for example, the method described in Science of Synthesis, 2006, 23, 391.).
[0432] Reference Production Method 16
[0433] The compound represented by formula (M2-Q4-1) can be produced according to the following scheme.
[0434]
[0435] [In the formula, the symbols represent the same meanings as described above.]
[0436] These reactions can be carried out in accordance with Reference Production Method 8.
[0437] The compound represented by formula (M2-Q4-5) is publicly known or can be produced according to publicly known methods (for example, the methods described in Journal of Heterocyclic Chemistry, 2013, 50, 1146. or Chemical Science, 2019, 10, 4328.).
[0438] The compounds of the present invention can be mixed or used in combination with one or more components selected from the following groups (a), (b), (c) and (d) (hereinafter referred to as this component).
[0439] The above-mentioned mixing or combination means that the compound of the present invention and this component are used simultaneously, separately or at intervals.
[0440] When the compound of the present invention and this component are used simultaneously, the compound of the present invention and this component can be contained in different preparations respectively, or can be contained in one preparation.
[0441] One aspect of the present invention is a composition (hereinafter referred to as composition A) containing one or more components selected from groups (a), (b), (c) and (d), and the compound of the present invention.
[0442] Group (a) is a group composed of acetylcholinesterase inhibitors (such as carbamate insecticides, organophosphorus insecticides), GABA-agonistic chloride channel antagonists (such as phenylpyrazole insecticides), sodium channel regulators (such as pyrethroid insecticides), nicotinic acetylcholine receptor antagonist regulators (such as neonicotinoid insecticides), allosteric regulators of nicotinic acetylcholine receptors, allosteric regulators of glutamate-agonistic chloride channels (such as macrolide insecticides), juvenile hormone analogs, multi-site inhibitors, chordotonal organ TRPV channel regulators, mite growth inhibitors, mitochondrial ATP synthase inhibitors, oxidative phosphorylation uncouplers, nicotinic acetylcholine receptor channel blockers (such as nereistoxin insecticides), chitin synthesis inhibitors, molting inhibitors, ecdysone receptor agonists, octopamine receptor agonists, mitochondrial electron transport system complex I·II·III·IV inhibitors, voltage-dependent sodium channel blockers, acetyl-CoA carboxylase inhibitors, ryanodine receptor regulators (such as diamide insecticides), chordotonal organ regulators, microbial insecticides, and other insecticidal active ingredients, acaricidal active ingredients and nematicidal active ingredients. These are recorded in the classification based on the mode of action of IRAC.
[0443] Group (b) is a group composed of nucleic acid synthesis inhibitors (such as phenylamide fungicides, acyl amino acid fungicides), cell division and cytoskeleton inhibitors (such as MBC fungicides), respiratory inhibitors (such as QoI fungicides, QiI fungicides), amino acid synthesis and protein synthesis inhibitors (such as anilinopyridine fungicides), signal transduction inhibitors, lipid synthesis and membrane synthesis inhibitors, sterol biosynthesis inhibitors (such as triazole DMI fungicides), cell wall synthesis inhibitors, melanin synthesis inhibitors, plant defense inducers, multi-site contact-active fungicides, microbial fungicides, and other fungicidal active ingredients. These are recorded in the classification based on the mode of action of FRAC.
[0444] Group (c) is a group of plant growth regulating components (including mycorrhizal fungi and rhizobia).
[0445] Group (d) is a group of repellent components.
[0446] Examples of the combination of the present component and the compound of the present invention are described below. For example, alanycarb + SX represents the combination of alanycarb and SX.
[0447] It should be noted that the abbreviation SX represents any one of the compound groups SX1 to SX28 of the present invention described in the examples. In addition, the present components described below are all well-known components, which can be obtained from commercially available preparations or can be manufactured by well-known methods. When the present component is a microorganism, it can also be obtained from a microorganism preservation institution. It should be noted that the numbers in parentheses represent CAS RN (registered trademark).
[0448] The combination of the present component of the above group (a) and the compound of the present invention:
[0449] Abamectin + SX, Acephate + SX, Acequinocyl + SX, Acetamiprid + SX, Acetoprole + SX, Acrinathrin + SX, Acynonapyr + SX, Afidopyropen + SX, Afoxolaner + SX, Alanycarb + SX, Aldicarb + SX, Allethrin + SX, Alpha-cypermethrin + SX, Alpha-endosulfan + SX, Aluminium phosphide + SX, Amitraz + SX, Azadirachtin + SX, Azamethiphos + SX, Azinphos-ethyl + SX, Azinphos-methyl + SX, Azocyclotin + SX, Bark of Celastrus angulatus + SX, Bendiocarb + SX, Benfluthrin + SX, Benfuracarb + SX, Bensultap + SX, Benzoximate + SX, Benzpyrimoxan + SX, Beta-cyfluthrin + SX, Beta-cypermethrin + SX, Bifenazate + SX, Bifenthrin + SX, Bioallethrin + SX, Bioresmethrin + SX, Bistrifluron + SX, Borax + SX, Boric acid + SX, Broflanilide + SX, Bromopropylate + SX, Buprofezin + SX, Butocarboxim + SX, Butoxycarboxim + SX, Cadusafos + SX, Calcium phosphide + SX, Carbaryl + SX, Carbofuran + SX, Carbosulfan + SX, Cartap hydrochloride + SX, Cartap + SX, Chinomethionat + SX, Chlorantraniliprole + SX, Chlordane + SX, Chlorethoxyfos + SX, Chlorfenapyr + SX, Chlorfenvinphos + SX, Chlorfluazuron + SX, Chlormephos + SX, Chloropicrin + SX, Chlorpyrifos + SX, Chlorpyrifos-methyl + SX, Chromafenozide + SX, Clofentezine + SX, Clothianidin + SX, ConcanamycinA) +SX, coumaphos+SX, cryolite+SX, cyanophos+SX, cyantraniliprole+SX, cyclaniliprole+SX, N-[2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide (cyclobutrifluram)+SX, cycloprothrin+SX, cycloxaprid+SX, cyenopyrafen+SX, cyetpyrafen+SX, cyflumetofen+SX, cyfluthrin+SX, cyhalodiamide+SX, cyhalothrin+SX, cyhexatin+SX, cypermethrin+SX, cyphenothrin+S, cyproflanilide+SX, cyromazine+SX, dazomet+SX, deltamethrin+SX, demeton-S-methyl+SX, diafenthiuron+SX, diazinon+SX, dichlorvos+SX, dicloromezotiaz+SX, dicofol+SX, dicrotophos+SX, diflovidazin+SX, diflubenzuron+SX, dimefluthrin+SX, dimethoate+SX, dimethylvinphos+SX, dimpropyridaz+SX, dinotefuran+SX, disodium octaborate+SX, disulfoton+SX, DNOC (2-methyl-4,6-dinitrophenol)+SX, doramectin+SX, dried leaves of Dryopterisfilix-mas)+SX, emamectin-benzoate)+SX, empenthrin)+SX, endosulfan)+SX, EPN (O-ethyl O-(4-nitrophenyl)phenyl phosphorothioate)+SX, epsilon-metofluthrin)+SX, epsilon-momfluorothrin)+SX, esfenvalerate)+SX, ethiofencarb)+SX, ethion)+SX, ethiprole)+SX, ethoprophos)+SX, etofenprox)+SX, etoxazole)+SX, extract of Artemisia absinthium)+SX, extract of Azadirachta indica)+SX, extract of Cassia nigricans)+SX, extract of clitoria ternatea)+SX, extract of Symphytum officinale)+SX, extracts or simulated blend of Chenopodium ambrosioides)+SX, extract of Tanacetum vulgare)+SX, extract of Urtica dioica)+SX, extract of Viscum album)+SX, famphur)+SX, fenamiphos)+SX, fenazaquin)+SX, fenbutatinoxide)+SX, fenitrothion+SX, fenmezoditiaz+SX, fenobucarb+SX, fenoxycarb+SX, fenpropathrin+SX, fenpyroximate+SX, fenthion+SX, fenvalerate+SX, fipronil+SX, flometoquin+SX, flonicamid+SX, fluacrypyrim+SX, fluazaindolizine+SX, fluazuron+SX, flubendiamide+SX, fluchlordiniliprole+SX, flucycloxuron+SX, flucythrinate+SX, fluensulfone+SX, flufenoprox+SX, flufenoxuron+SX, flufiprole+SX, flumethrin+SX, flupentiofenox+SX, flupyradifurone+SX, flupyrimin+SX, fluralaner+SX, fluvalinate+SX, fluorine Fluxametamide + SX, Formetanate + SX, Fosthiazate + SX, Furamethrin + SX, Furathiocarb + SX, Gamma-cyhalothrin + SX, Glutamine synthetase-omega / kappa HXTX-Hv1a peptide + SX, Hafenprox + SX, Halofenozide + SX, Heptafluthrin + SX, Heptenophos + SX, Hexaflumuron + SX, Hexythiazox + SX, Potassium salt of hop beta acid + SX, Hydramethylnon + SX, Hydroprene + SX, Imicyafos + SX, Imidacloprid + SX, Imidaclothiz + SX, Imiprothrin + SX, Indazapyroxamet + SX, Indoxacarb + SX, Isocycloseram + SX, Isofenphos + SX, Isoprocarb + SX, Isopropyl-O-(methoxyaminothiophosphoryl)salicylate + SX, Iso Isoxathion + SX, Ivermectin + SX, Kadethrin + SX, Kappa - tefluthrin + SX, Kappa - bifenthrin + SX, Kinoprene + SX, Lambda - cyhalothrin + SX, Lepimectin + SX, Lime sulfur + SX, Lotilaner + SX, Lufenuron + SX, Machine oil + SX, Malathion + SX, Mecarbam + SX, Meperfluthrin + SX, Metaflumizone + SX, Metam + SX, Methamidophos + SX, Methidathion + SX, Methiocarb + SX, Methomyl + SX, Methoprene + SX, Methoxychlor + SX, Methoxyfenozide + SX, Methyl bromide + SX, Metofluthrin + SX, Metolcarb + SX, Metoxadiazone + SX, Mevinphos + SX, Milbemectin + SX, Milbemycin oxime + SX, Momfluorothrin + SX, Monocrotophos + SX, Moxidectin + SX, Naled + SX, Nicofluprole + SX, Nicotine + SX, Nicotine - sulfate + SX, Nitenpyram + SX, Novaluron + SX, Noviflumuron + SX, Oil of the seeds of Chenopodium anthelminticum + SX, Omethoate + SX, Oxamyl + SX, Oxazosulfyl + SX, Oxydemeton - methyl + SX, Parathion + SX, Parathion - methyl + SX, Permethrin + SX, Phenothrin + SX, Phenthoate + SX, Phorate + SX, Phosalone + SX, Phosmet + SX, Phosphamidon + SX, Phosphine + SX, Phoxim + SX, Pirimicarb + SX, Pirimiphos - methyl + SX, Prallethrin + SX, Profenofos + SX, Profluthrin + SX, Propargite + SX, Propetamphos + SX, Propoxur + SX, Propylene glycolalginate)+SX, prothiofos)+SX, pyflubumide)+SX, pymetrozine)+SX, pyraclofos)+SX, pyrethrins)+SX, pyridaben)+SX, pyridalyl)+SX, pyridaphenthion)+SX, pyrifluquinazone)+SX, pyrimidifen)+SX, pyriminostrobin)+SX, pyriprole)+SX, pyriproxyfen)+SX, quinalphos)+SX, resmethrin)+SX, rotenone)+SX, ryanodine)+SX, sarolaner+SX, selamectin)+SX, sigma-cypermethrin)+SX, silafluofen)+SX, sodium borate)+SX, sodiummetaborate)+SX, spinetoram)+SX, spinosad)+SX, spirodiclofen)+SX, spiromesifen)+SX, spiropidion+SX, spirotetramat)+SX, sulfluramid)+SX, sulfotep)+SX, sulfoxaflor)+SX, sulfur)+SX, sulfuryl fluoride)+SX, tartaremetic)+SX, tau-fluvalinate)+SX, tebufenozide)+SX, tebufenpyrad)+SX, tebupirimfos)+SX, teflubenzuron)+SX, tefluthrin)+SX, temephos)+SX, terbufos)+SX, terpene constituents of the extract of chenopodium ambrosioidesnearambrosioides)+SX, tetrachlorantraniliprole)+SX, tetrachlorvinphos)+SX, tetradifon)+SX, tetramethrin)+SX, tetramethylfluthrin)+SX, tetraniliprole)+SX, theta-cypermethrin)+SX, thiacloprid)+SX, thiamethoxam)+SX, thiocyclam)+SX, thiodicarb)+SX, thiofanox)+SX, thiometon)+SX, thiosultap-disodium)+SX, thiosultap-monosodium)+SX, tioxazafen+SX, tolfenpyrad)+SX, tralomethrin)+SX, transfluthrin)+SX, triazamate)+SX, triazophos)+SX, trichlorfon)+SX, triflumezopyrim)+SX, triflumuron)+SX, trimethacarb)+SX, tyclopyrazoflor+SX, vamidothion)+SX, wood extract of Quassia amara)+SX, XMC (3,5-dimethylphenyl N-methylcarbamate)+SX, xylylcarb)+SX, zeta-cypermethrin)+SX, zinc phosphide)+SX, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2- oxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (1241050-20-3)+SX, 3-methoxy-N-(5-{5-(trifluoromethyl)-5-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2- {2-oxo-2-[(1H-1,2,4-triazol-1-yl)methyl]ethyl} 2-({2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (1118626-57-5) + SX, 2-({2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (1445683-71-5) + SX, (2Z)-2-({2-fluoro-4-methyl-5-[(R)-(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (2377084-09-6) + SX, N-{4-chloro-3-[(1-cyanocyclopropyl)carbamoyl]phenyl}-1-methyl-4-(methylsulfonyl)-3-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazole-3-carboxamide (1400768-21-9) + SX, N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-(methylsulfonyl)propanamide (2396747-83-2) + SX, 1,4-dimethyl-2-[2-(pyridin-3-yl)-2H-indazol-5-yl]-1,2,4-triazoline-3,5-dione (2171099-09-3) + SX, 2-isopropyl-5-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-1,3,4-thiadiazole (2058052-95-0) + SX, N-({2-fluoro-4-[(2S,3S)-2-hydroxy-3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl}methyl)cyclopropanecarboxamide + SX, 7-fluoro-N-[1-(methylthio)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 7-fluoro-N-[1-(methylsulfinyl)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 7-fluoro-N-[1-(methylsulfonyl)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, N-(1-methylcyclopropyl)-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 2,9-dihydro-9-(methoxymethyl)-2-(pyridin-3-yl)-10H-pyrazolo[3,4-f]pyrido[2,3-b][1,4]oxazine -10-ketone (2607927-97-7) + SX, BT crop protein Cry1Ab + SX, BT crop protein Cry1Ac + SX, BT crop protein Cry1Fa + SX, BT crop protein Cry1A.105 + SX, BT crop protein Cry2Ab + SX, BT crop protein Vip3A + SX, BT crop protein mCry3A + SX, BT crop protein Cry3Ab + SX, BT crop protein Cry3Bb + SX, BT crop protein Cry34Ab1 / Cry35Ab1 + SX, Adoxophyes orana granulosis virus strain BV-0001 + SX, Anticarsia gemmatalis mNPV + SX, Autographa californica mNPV + SX, Cydia pomonella GV strain V15 + SX, Cydia pomonella GV strain V22 + SX, Cryptophlebia leucotreta GV + SX, Dendrolimus punctatus cypovirus + SX, Helicoverpa armigera NPV strain BV-0003 + SX, Helicoverpa zea NPV + SX, Lymantria dispar NPV + SX, Mamestra brassicaeNPV) + SX, Mamestra configurata NPV + SX, Neodiprion abietis NPV + SX, Neodiprion lecontei NPV + SX, Neodiprion sertifer NPV + SX, Nosema locustae + SX, Orgyia pseudotsugata NPV + SX, Pieris rapae GV + SX, Plodia interpunctella GV + SX, Spodoptera exigua mNPV + SX, Spodoptera littoralis mNPV + SX, Spodoptera litura NPV + SX, Arthrobotrys dactyloides + SX, Bacillus firmus strain GB-126 + SX, Bacillus firmus strain I-1582 + SX, Bacillus firmus strain NCIM2637 + SX, Bacillus megaterium + SX, Bacillus sp. strain AQ175 + SX, Bacillus sp. strain AQ177 + SX, Bacillus sp. strain AQ178 + SX, Bacillus sphaericus strain 2362 serotype H5a5b + SX, Bacillus sphaericus strain ABTS1743 + SX, Bacillus sphaericus Serotype strain H5a5b + SX, Bacillus thuringiensis strain AQ52 + SXBacillus thuringiensis strain AQ52 + SX, Bacillus thuringiensis strain BD#32 + SX, Bacillus thuringiensis strain CR-371 + SX, Bacillus thuringiensis subsp. Aizawai strain ABTS-1857 + SX, Bacillus thuringiensis subsp. Aizawai strain AM65-52 + SX, Bacillus thuringiensis subsp. Aizawai strain GC-91 + SX, Bacillus thuringiensis subsp. Aizawai strain NB200 + SX, Bacillus thuringiensis subsp. Aizawai Serotype strain H-7 + SX, Bacillus thuringiensis subsp. Kurstaki strain ABTS351 + SX, Bacillus thuringiensis subsp. Kurstaki strain BMP123 + SX, Bacillus thuringiensis subsp. Kurstaki strain CCT1306 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG2348 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG7841 + SX, Bacillus thuringiensis subsp. Kurstaki strain EVB113-19 + SXEVB113 - 19)+SX, Bacillus thuringiensis subsp. Kurstaki strain F810+SX, Bacillus thuringiensis subsp. Kurstaki strain HD - 1+SX, Bacillus thuringiensis subsp. Kurstaki strain PB54+SX, Bacillus thuringiensis subsp. Kurstaki strain SA - 11+SX, Bacillus thuringiensis subsp. Kurstaki strain SA - 12+SX, Bacillus thuringiensis subsp. Tenebriosis strain NB176+SX, Bacillus thuringiensis subsp. Thuringiensis strain MPPL002+SX, Bacillus thuringiensis subsp. morrisoni+SX, Bacillus thuringiensis var. colmeri+SX, Bacillus thuringiensis var. darmstadiensis strain 24 - 91+SX, Bacillus thuringiensis var. dendrolimus+SX, Bacillus thuringiensis var. galleriae+SX, Bacillus thuringiensis var. israelensis strain BMP144+SX, Bacillus thuringiensis var. israelensis serotype strain H - 14+SXH-14)+SX, Bacillus thuringiensis var. japonensis strain buibui +SX, Bacillus thuringiensis var. san diego strain M-7 +SX, Bacillus thuringiensis var. 7216 +SX, Bacillus thuringiensis var. aegypti +SX, Bacillus thuringiensis var. T36 +SX, Beauveria bassiana strain ANT-03 +SX, Beauveria bassiana strain ATCC74040 +SX, Beauveria bassiana strain GHA +SX, Beauveria brongniartii +SX, Burkholderia rinojensis strain A396 +SX, Chromobacterium subtsugae strain PRAA4-1T +SX, Dactyllela ellipsospora +SX, Dectylariathaumasia +SX, Hirsutella minnesotensis +SX, Hirsutella rhossiliensis +SX, Hirsutella thompsonii +SX, Lagenidium giganteum +SX, Lecanicillium lecanii strain KV01 +SX, Lecanicillium lecanii conidia of strain DAOM198499 +SX, Lecanicillium lecanii conidia of strain DAOM216596 +SX,DAOM216596)+SX, Lecanicillium muscarium strain Ve6)+SX, Metarhizium anisopliae strain F52)+SX, Metarhizium anisopliae var.acridum)+SX, Metarhizium anisopliae var.anisopliae BIPESCO 5 / F52)+SX, Metarhizium flavoviride)+SX, Monacrosporium phymatopagum)+SX, Paecilomyces fumosoroseus Apopka strain 97)+SX, Paecilomyces lilacinus strain 251)+SX, Paecilomyces tenuipes strain T1)+SX, Paenibacillus popilliae)+SX, Pasteuria nishizawae strain Pn1)+SX, Pasteuria penetrans)+SX, Pasteuria usgae)+SX, Pasteuria thornei)+SX, Serratia entomophila)+SX, Verticillium chlamydosporium)+SX, Verticillium lecani strain NCIM1312)+SX, Wolbachia pipientis)+SX.
[0450] The combination of the present component of group (b) and the compound of the present invention:
[0451] acibenzolar-S-methyl + SX, aldimorph + SX, ametoctradin + SX, aminopyrifen + SX, amisulbrom + SX, anilazine + SX, azaconazole + SX, azoxystrobin + SX, basic coppersulfate + SX, benalaxyl + SX, benalaxyl-M + SX, benodanil + SX, benomyl + SX, benthiavalicarb + SX, benthivalicarb-isopropyl + SX, benzovindiflupyr + SX, binapacryl + SX, biphenyl + SX, bitertanol + SX, bixafen + SX, blasticidin-S + SX, Bordeaux mixture + SX, boscalid + SX, bromothalonil + SX, bromuconazole + SX, bupirimate + SX, captafol + SX, captan + SX, carbendazim + SX, carboxin + SX, carpropamid + SX, chinomethionat + SX, chitin + SX, chloroinconazide + SX, chloroneb + SX, chlorothalonil + SX, chlozolinate + SX, colletochlorinB + SX, copper(II)acetate + SX, copper(II)hydroxide + SX, copperoxychloride + SX, copper(II)sulfate + SX, coumoxystrobin + SX, cyazofamid + SX, cyflufenamid + SX, cymoxanil + SX, cyproconazole + SX, cyprodinil + SX, dichlobentiazox + SX, dichlofluanid + SX, diclocymet + SX, diclomezine + SX, dicloran + SX, diethofencarb + SX, difenoconazole + SX, diflumetorim + SX, dimethachlone + SX, dimethirimol + SX, dimethomorph + SX, dimoxystrobin + SX, diniconazole + SX, diniconazole-M + SX, dinocap + SX, dipotassiumhydrogenphosphite + SX, dipymetitrone + SX, dithianon + SX, dodecylbenzenesulphonic acid bisethylenediamine copper(II)salt + SX, dodemorph + SX, dodine + SX, edifenphos + SX, enoxastrobin + SX, epoxiconazole + SX, etaconazole + SX, ethaboxam + SX, ethirimol + SX, etridiazole + SX, extract from Melaleuca alternifolia + SX, extract from Polygonum cuspidatum + SXReynoutria sachalinensis)+SX, extract from the cotyledons of lupine plantlets(“BLAD”))+SX, extract of Allium sativum)+SX, extract of Equisetum arvense)+SX, extract of Tropaeolum majus)+SX, Famoxadone + SX, Fenamidone + SX, Fenaminstrobin + SX, Fenarimol + SX, Fenbuconazole + SX, Fenfuram + SX, Fenhexamid + SX, Fenoxanil + SX, Fenpiclonil + SX, Fenpicoxamid + SX, Fenpropidin + SX, Fenpropimorph + SX, Fenpyrazamine + SX, Fentin acetate, Fentinchloride, Fentin hydroxide, Ferbam, Ferimzone, Florylpicoxamid, Fluazinam, Flubeneteram, Fludioxonil, Flufenoxystrobin, Fluindapyr, Flumorph, Fluopicolide, Fluopyram, Fluopimomide, Fluoroimide, Fluoxapiprolin, Fluoxastrobin, Fluoxytioconazole, Fluquinconazole, Flusilazole, Flusulfamide, Flutianil, Flutolanil, Flutriafol, Fluxapyroxad, Folpet, Fosetyl, Fosetyl - aluminium, Fuberidazole, Furalaxyl, Furametpyr, Guazatine, Hexaconazole, Hymexazole + SX, Imazalil + SX, Imibenconazole + SX, Iminoctadine + SX, Iminoctadine triacetate + SX, Inpyrfluxam + SX, Iodocarb + SX, Ipconazole + SX, Ipfentrifluconazole + SX, Ipflufenoquin + SX, Iprobenfos + SX, Iprodione + SX, Iprovalicarb + SX, Isofetamid + SX, Isoflucypram + SX, Isoprothiolane + SX, Isopyrazam + SX, Isotianil + SX, Kasugamycin + SX, Kresoxim-methyl + SX, Laminarin + SX, Leaves and bark of Quercus + SX, Mancozeb + SX, Mandestrobin + SX, Mandipropamid + SX, Maneb + SX, Mefentrifluconazole + SX, Mepanipyrim + SX, Mepronil + SX, Meptyldinocap + SX, Metalaxyl + SX, Metalaxyl-M + SX, Metarylpicoxamid + SX, Metconazole + SX, Methasulfocarb + SX, Metiram + SX, Metominostrobin + SX, Metrafenone + SX, Metyltetraprole + SX, Myclobutanil + SX, Naftifine + SX, Nuarimol + SX, Octhilinone + SX, Ofurace + SX, Orysastrobin + SX, Oxadixyl + SX, Oxathiapiprolin + SX, Oxine - copper + SX, Oxolinic acid + SX, Oxpoconazole + SX, oxpoconazole fumarate + SX, oxycarboxin + SX, oxytetracycline + SX, pefurazoate + SX, penconazole + SX, pencycuron + SX, penflufen + SX, penthiopyrad + SX, phenamacril + SX, phosphorous acid + SX, phthalide + SX, picarbutrazox + SX, picoxystrobin + SX, piperalin + SX, polyoxins + SX, potassium hydrogencarbonate + SX, potassium dihydrogenphosphite + SX, probenazole + SX, prochloraz + SX, procymidone + SX, propamidine + SX, propamocarb + SX, propiconazole + SX, propineb + SX, proquinazid + SX, prothiocarb + SX, prothioconazole + SX, pydiflumetofen + SX, pyraclostrobin + SX, pyrametostrobin + SX, pyraoxystrobin + SX, pyrapropoyne + SX, pyraziflumid + SX, pyrazophos + SX, pyribencarb + SX, pyributicarb, pyridachlometyl + SX, pyrifenox + SX, pyrimethanil + SX, pyrimorph + SX, pyriofenone + SX, pyrisoxazole + SX, pyroquilon + SX, Quillaja extract + SX, quinconazole + SXquinofumelin + SX, quinoxyfen + SX, quintozene + SX, Saponins of Chenopodium quinoa + SX, seboctylamine + SX, sedaxane + SX, silthiofam + SX, simeconazole + SX, sodium hyhydrogencarbonate + SX, spiroxamine + SX, streptomycin + SX, sulfur + SX, tebuconazole + SX, tebufloquin + SX, teclofthalam + SX, tecnazene + SX, terbinafine + SX, tetraconazole + SX, thiabendazole + SX, thifluzamide + SX, thiophanate + SX, thiophanate-methyl + SX, thiram + SX, thymol + SX, tiadinil + SX, tolclofos-methyl + SX, tolfenpyrad + SX, tolprocarb + SX, tolylfluanid + SX, triadimefon + SX, triadimenol + SX, triazoxide + SX, triclopyricarb + SX, tricyclazole + SX, tridemorph + SX, trifloxystrobin + SX, triflumizole + SX, triforine + SX, triticonazole + SX, validamycin + SX, valifenalate + SX, vinclozolin + SX, yellow mustard powder + SX, zinc thiazole + SX, zineb + SX, ziram + SX,Zoxamide + SX, N’-[4-({3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl}oxy)-2,5-dimethylphenyl]-N-ethyl-N-methylmethanimidamide (1202781-91-6) + SX, N’-{4-[(4,5-dichlorothiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylmethanimidamide (929908-57-6) + SX, N’-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methylmethanimidamide (1052688-31-9) + SX, N’-[5-chloro-4-(2-fluorophenoxy)-2-methylphenyl]-N-ethyl-N-methylformimidamide (2055589-28-9) + SX, N’-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylformimidamide (2055756-21-1) + SX, N’-(2-chloro-4-phenoxy-5-methylphenyl)-N-ethyl-N-methylformimidamide (2062599-39-5) + SX, N’-[4-(1-hydroxy-1-phenyl-2,2,2-trifluoroethyl)-2-methyl-5-methoxyphenyl]-N-isopropyl-N-methylformimidamide (2101814-55-3) + SX, N’-[5-bromo-6-(1-methyl-2-propoxyethoxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylformimidamide (1817828-69-5) + SX, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine (1362477-26-6) + SX, 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline (1257056-97-5) + SX, (2Z)-3-amino-2-cyano-3-phenylacrylic acid ethyl ester (39491-78-6) + SX, N-[(2-chlorothiazol-5-yl)methyl]-N-ethyl-6-methoxy-3-nitropyridin-2-amine (1446247-98-8) + SX, 5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1394057-11-4) + SX, (1R,2S,5S)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-06-2) + SX, (1S,2R,5R)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-07-3) + SX,2-Chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1394057-13-6) + SX, (1R,2S,5S)-2-(Chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-08-4) + SX, (1S,2R,5R)-2-Chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-09-5) + SX, Methyl 3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate (1791398-02-1) + SX, 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[1-(4-bromo-2,6-difluorophenoxy)cyclopropyl]ethanol (2019215-86-0) + SX, 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[1-(4-chloro-2,6-difluorophenoxy)cyclopropyl]ethanol (2019215-84-8) + SX, 1-[2-(1-Chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxypropyl]-1H-imidazole-5-carbonitrile (2018316-13-5) + SX, 1-[2-(1-Chlorocyclopropyl)-3-(2,3-difluorophenyl)-2-hydroxypropyl]-1H-imidazole-5-carbonitrile (2018317-25-2) + SX, 2-[6-(4-Bromophenoxy)-2-(trifluoromethyl)pyridin-3-yl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol (2082661-43-4) + SX, 2-[6-(4-Chlorophenoxy)-2-(trifluoromethyl)pyridin-3-yl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol (2082660-27-1) + SX, Methyl ({2-methyl-5-[1-(4-methoxy-2-methylphenyl)-1H-pyrazol-3-yl]phenyl}methyl)carbamate (1605879-98-8) + SX, 2-(Difluoromethyl)-N-[1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1616239-21-4) + SX, 2-(Difluoromethyl)-N-[3-ethyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1847460-02-9) + SX, 2-(Difluoromethyl)-N-[3-propyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1847460-05-2) + SX,(2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide (1445331-27-0) + SX, (2E,3Z)-5-{[1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide (1445331-54-3) + SX, 5-chloro-4-({2-[6-(4-chlorophenoxy)pyridin-3-yl]ethyl}amino)-6-methylpyrimidine (1605340-92-8) + SX, N-(1-phenyl-1,3-dimethylbutyl)-8-fluoroquinoline-3-carboxamide (2132414-04-9) + SX, N-(1-phenyl-3,3,3-trifluoro-1-methylpropyl)-8-fluoroquinoline-3-carboxamide (2132414-00-5) + SX, 4,4-dimethyl-2-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)is oxazolidin-3-one (2098918-25-1) + SX, 5,5-dimethyl-2-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)is oxazolidin-3-one (2098918-26-2) + SX, N-ethyl-2-methyl-N-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)propanamide + SX, N,2-dimethoxy-N-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)propanamide + SX, N-methoxy-N-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)cyclopropanecarboxamide + SX, N-methoxy-N'-methyl-N-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)urea + SX, N'-ethyl-N-methoxy-N-({4-[5-(trifluoromethyl)-1,2,4- diazol-3-yl]phenyl}methyl)urea + SX, N,N'-dimethoxy-N-({4-[5-(trifluoromethyl)-1,2,4- {[1,2,4]triazol-3-yl}phenyl}methyl)urea + SX, N-acetyl-2-(ethylsulfonyl)-N-[2-(methoxycarbonyl)-4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)benzamide (2043675-28-9) + SX, 3-(4-bromo-7-fluoroindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(7-bromoindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(7-bromo-4-fluoroindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(3,5-dichloropyridin-2-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(3,5-dichloropyridin-2-yl)butan-2-yl N-{[3-(acetyloxymethoxy)-4-methoxypyridin-2-yl]carbonyl}-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-[(3-acetyloxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-{[3-(acetyloxymethoxy)-4-methoxypyridin-2-yl]carbonyl}-L-alaninate + SX, Agrobacterium radiobactor strain K1026 + SX, Agrobacterium radiobactor strain K84 + SX, Bacillus amyloliquefaciens strain PTA-4838, Aveo (trademark) EZ Nematicide + SX, Bacillus amyloliquefaciens strain AT332 + SX, Bacillus amyloliquefaciens strain B3 + SX, Bacillus amyloliquefaciens strain D747 + SX, Bacillus amyloliquefaciens strain DB101 + SX, Bacillus amyloliquefaciens strainBacillus amyloliquefaciens strain DB101 + SX, Bacillus amyloliquefaciens strain DB102 + SX, Bacillus amyloliquefaciens strain GB03 + SX, Bacillus amyloliquefaciens strain FZB24 + SX, Bacillus amyloliquefaciens strain FZB42 + SX, Bacillus amyloliquefaciens strain IN937a + SX, Bacillus amyloliquefaciens strain MBI600 + SX, Bacillus amyloliquefaciens strain QST713 + SX, Bacillus amyloliquefaciens isolate strain B246 + SX, Bacillus amyloliquefaciens strain F727 + SX, Bacillus amyloliquefaciens subsp. plantarum strain D747 + SX, Bacillus licheniformis strain HB-2 + SX, Bacillus licheniformis SB3086 + SX, Bacillus pumilus strain AQ717 + SX, Bacillus pumilus strain BUF-33 + SX, Bacillus pumilus GB34 + SX, Bacillus pumilus strain QST2808 + SX, Bacillus simplex strain CGF2856 + SX, Bacillus subtilis strain AQ153Bacillus subtilis strain AQ153 + SX, Bacillus subtilis strain AQ743 + SX, Bacillus subtilis strain BU1814 + SX, Bacillus subtilis strain D747 + SX, Bacillus subtilis strain DB101 + SX, Bacillus subtilis strain FZB24 + SX, Bacillus subtilis strain GB03 + SX, Bacillus subtilis strain HAI0404 + SX, Bacillus subtilis strain IAB / BS03 + SX, Bacillus subtilis strain MBI600 + SX, Bacillus subtilis strain QST30002 / AQ30002 + SX, Bacillus subtilis strain QST30004 / AQ30004 + SX, Bacillus subtilis strain QST713 + SX, Bacillus subtilis strain QST714 + SX, Bacillus subtilis var. Amyloliquefaciens strain FZB24 + SX, Bacillus subtilis strain Y1336 + SX, Burkholderia cepacia, Burkholderia cepacia type Wisconsin strain J82 + SX, Burkholderia cepacia type Wisconsin strain M54M54)+SX, Candida oleophila strain O)+SX, Candida saitoana)+SX, Chaetomium cupreum)+SX, Clonostachys rosea)+SX, Coniothyrium minitans strain CGMCC8325)+SX, Coniothyrium minitans strain CON / M / 91-8)+SX, cryptococcus albidus)+SX, Erwinia carotovora strain CGE234M403)+SX, Fusarium oxysporum strain Fo47)+SX, Gliocladium catenulatum strain J1446)+SX, Paenibacillus polymyxa strain AC-1)+SX, Paenibacillus polymyxa strain BS-0105)+SX, Pantoea agglomerans strain E325)+SX, Phlebiopsis gigantea strain VRA1992)+SX, Pseudomonas aureofaciens strain TX-1)+SX, Pseudomonas chlororaphis strain 63-28)+SX, Pseudomonas chlororaphis strain AFS009)+SX, Pseudomonas chlororaphis strain MA342)+SX, Pseudomonas fluorescens strain 1629RS)+SX, Pseudomonas fluorescens strain A506)+SXA506)+SX, Pseudomonas fluorescens strain CL145A+SX, Pseudomonas fluorescens strain G7090+SX, Pseudomonas sp. strain CAB-02+SX, Pseudomonas syringae strain 742RS+SX, Pseudomonas syringae strain MA-4+SX, Pseudozyma flocculosa strain PF-A22UL+SX, Pseudomonas rhodesiae strain HAI-0804+SX, Pythium oligandrum strain DV74+SX, Pythium oligandrum strain M1+SX, Streptomyces griseoviridis strain K61+SX, Streptomyces lydicus strain WYCD108US+SX, Streptomyces lydicus strain WYEC108+SX, Talaromyces flavus strain SAY-Y-94-01+SX, Talaromyces flavus strain V117b+SX, Trichoderma asperellum strain ICC012+SX, Trichoderma asperellum SKT-1+SX, Trichoderma asperellum strain T25+SX, Trichoderma asperellum strain T34+SX, Trichoderma asperellum strain TV1+SX, Trichoderma atroviride CNCMTrichoderma atroviride strain CNCM 1-1237 + SX, Trichoderma atroviride strain LC52 + SX, Trichoderma atroviride strain IMI 206040 + SX, Trichoderma atroviride strain SC1 + SX, Trichoderma atroviride strain SKT-1 + SX, Trichoderma atroviride strain T11 + SX, Trichoderma gamsii strain ICC080 + SX, Trichoderma harzianum strain 21 + SX, Trichoderma harzianum strain DB104 + SX, Trichoderma harzianum strain DSM14944 + SX, Trichoderma harzianum strain ESALQ-1303 + SX, Trichoderma harzianum strain ESALQ-1306 + SX, Trichoderma harzianum strain IIHR-Th-2 + SX, Trichoderma harzianum strain ITEM908 + SX, Trichoderma harzianum strain kd + SX, Trichoderma harzianum strain MO1 + SX, Trichoderma harzianum strain SF + SX, Trichoderma harzianum strain T22 + SX, Trichoderma harzianum strain T39 + SX, Trichoderma harzianum strain T78 + SXT78)+SX, Trichoderma harzianum strain TH35)+SX, Trichoderma polysporum strain IMI206039)+SX, trichodermastromaticum)+SX, Trichoderma virens G-41)+SX, Trichoderma virens GL-21)+SX, Trichoderma viride)+SX, Variovorax paradoxus strain CGF4526)+SX, Harpin protein)+SX.
[0452] The combination of the component of the above group (c) and the compound of the present invention:
[0453] 1-methylcyclopropene + SX, 1,3-diphenylurea + SX, 2,3,5-triiodobenzoic acid + SX, IAA ((1H-indol-3-yl)acetic acid) + SX, IBA (4-(1H-indol-3-yl)butyric acid) + SX, MCPA (2-(4-chloro-2-methylphenoxy)acetic acid) + SX, MCPB (4-(4-chloro-2-methylphenoxy)butyric acid) + SX, 4-CPA (4-(4-chlorophenoxyacetic acid)) + SX, 5-aminolevulinic acid hydrochloride + SX, 6-benzylaminopurine + SX, abscisic acid + SX, AVG (aminoethoxyvinylglycine) + SX, 2-fluoro-N-(3-methoxyphenyl)-7H-purin-6-amine (anisiflupurin) + SX, ancymidol + SX, butralin + SX, calcium carbonate + SX, calcium chloride + SX, calcium formate + SX, calcium peroxide + SX, calcium polysulfide + SX, calcium sulfate + SX, chlormequat-chloride + SX, chlorpropham + SX, cholinechloride)+SX, cloprop)+SX, cyanamide)+SX, cyclanilide)+SX, daminozide)+SX, decan-1-ol)+SX, dichlorprop)+SX, dikegulac)+SX, dimethipin)+SX, diquat)+SX, ethephon)+SX, ethychlozate)+SX, flumetralin)+SX, flurprimidol)+SX, forchlorfenuron)+SX, formononetin)+SX, Gibberellin A)+SX, Gibberellin A3)+SX, inabenfide)+SX, Kinetin)+SX, lipochitooligosaccharide SP104)+SX, mefluidide)+SX, mepiquat-chloride)+SX, oxidized glutathione)+SX, pacrobutrazol)+SX, pendimethalin)+SX, prohexandione-calcium)+SX, prohydrojasmon)+SX, pyraflufen-ethyl)+SX, sintofen)+SX, sodium 1-naphthaleneacetate)+SX, sodium cyanate)+SX, thidiazuron)+SX, triapenthenol)+SX, Tribufos)+SX, trinexapac-ethyl)+SX, uniconazole-P)+SX, 2-(naphthalene-1-yl)acetamide)+SX, [4-oxo-4-(2-phenylethyl)amino]butyric acid+SX, methyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate+SX, 3-[(6-chloro-4-phenylquinazolin-2-yl)amino]-1-propanol+SX, Claroideoglomusetunicatum)+SX, Claroideoglomus claroideum)+SX, Funneliformis mosseae)+SX, Gigaspora margarita)+SX, Gigaspora rosea)+SX, Glomus aggregatum)+SX, Glomus deserticola)+SX, Glomus monosporum)+SX, Paraglomus brasillianum)+SX, Rhizophagus clarus)+SX, Rhizophagus intraradices RTI-801)+SX, Rhizophagus irregularis DAOM 197198)+SX, Azorhizobium caulinodans)+SX, Azospirillum amazonense)+SX, Azospirillum brasilense XOH)+SX, Azospirillum brasilense Ab-V5)+SX, Azospirillum brasilense Ab-V6)+SX, Azospirillum caulinodans+SX, Azospirillum halopraeferens+SX, Azospirillum irakense)+SX, Azospirillum lipoferum)+SX, Bradyrhizobium elkanii SEMIA587)+SX, Bradyrhizobium elkanii SEMIA5019)+SX, Bradyrhizobium japonicum TA-11)+SX, Bradyrhizobium japonicum USDA 110)+SX, BradyrhizobiumLiaoningense)+SX, Bradyrhizobium lupini)+SX, Delftia acidovorans RAY209)+SX, Mesorhizobium ciceri)+SX, Mesorhizobium huakii)+SX, Mesorhizobium loti)+SX, Rhizobium etli)+SX, Rhizobium galegae)+SX, Rhizobium leguminosarum bv. phaseoli)+SX, Rhizobium leguminosarum bv. Trifolii)+SX, Rhizobium leguminosarum bv. Viciae)+SX, Rhizobium trifolii)+SX, Rhizobium tropici)+SX, Sinorhizobium fredii)+SX, Sinorhizobium meliloti)+SX, Zucchini Yellow Mosaik Virus weak strain)+SX.
[0454] The combination of the component of the above group (d) and the compound of the present invention:
[0455] Anthraquinone)+SX, Deet)+SX, Icaridin)+SX.
[0456] The ratio of the compound of the present invention to this component is not particularly limited, and examples of the weight ratio (compound of the present invention: this component) include 1000:1 to 1:1000, 500:1 to 1:500, 100:1 to 1:100, 50:1, 20:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:20, 1:50, etc.
[0457] The compounds of the present invention are effective against harmful arthropods such as harmful insects and harmful mites, harmful nematodes, and harmful mollusks. Examples of harmful arthropods, harmful nematodes, and harmful mollusks are as follows.
[0458] Hemiptera: Delphacidae such as Laodelphax striatellus, Nilaparvatalugens, Sogatella furcifera, Peregrinus maidis, Javesella pellucida, Perkinsiella saccharicida, Tagosodes orizicolus, etc.; Cicadellidae such as Nephotettix cincticeps, Nephotettix virescens, Nephotettix nigropictus, Recilia dorsalis, Empoasca onukii, Empoasca fabae, Dalbulus maidis, Cofana spectra, etc.; Aphrophoridae such as Philaenus spumarius; Cercopidae such as Mahanarva posticata, Mahanarva fimbriolata, etc.Aphididae such as Aphis fabae, Aphis glycines, Aphis gossypii, Aphis pomi, Aphis spiraecola, Myzus persicae, Brachycaudus helichrysi, Brevicoryne brassicae, Dysaphis plantaginea, Lipaphis erysimi, Macrosiphum euphorbiae, Aulacorthum solani, Nasonovia ribisnigri, Rhopalosiphum padi, Rhopalosiphum maidis, Toxoptera citricida, Hyalopterus pruni, Melanaphis sacchari, Tetraneura nigriabdominalis, Ceratovacuna lanigera, Eriosoma lanigerum, Sitobion avenae; Phylloxeridae such as Daktulosphaira vitifoliae, Phylloxera devastatrix, Phylloxera notabilis, Phylloxera russellae; Adelgidae such as Adelges tsugae, Adelges piceae, Aphrastasia pectinataePentatomidae such as Scotinophara lurida, Scotinophara coarctata, Nezara antennata, Eysarcoris aeneus, Eysarcoris lewisi, Eysarcoris ventralis, Eysarcoris annamita, Halyomorpha halys, Nezara viridula, Euschistus heros, Piezodorus guildinii, Oebalus pugnax, Dichelops melacanthus, etc.; Cydnidae such as Scaptocoris castanea, etc.; Alydidae such as Riptortus clavatus, Leptocorisa chinensis, Leptocorisa acuta, etc.; Coreidae such as Cletus punctiger, Leptoglossus australis, etc.; Lygaeidae such as Caverelius saccharivorus, Togo hemipterus, Blissus leucopterus, etc.; Miridae such as Trigonotylus caelestialium, Stenotus rubrovittatus, Stenodema calcarata, Lygus lineolaris, etc.; Aleyrodidae such as Trialeurodes vaporariorum, Bemisia tabaci, Dialeurodes citri, Aleurocanthus spiniferus, Aleurocanthus camelliae, Pealius euryae, etc.Scale insects in the family Diaspididae such as Abgrallaspis cyanophylli, Aonidiella aurantii, Diaspidiotus perniciosus, Pseudaulacaspis pentagona, Unaspis yanonensis, Unaspis citri, etc.; scale insects in the family Coccidae such as Ceroplastes rubens; scale insects in the family Margarodidae such as Icerya purchasi, Icerya seychellarum; scale insects in the family Pseudococcidae such as Phenacoccus solani, Phenacoccus solenopsis, Planococcus kraunhiae, Pseudococcus comstocki, Planococcus citri, Pseudococcus calceolariae, Pseudococcus longispinus, Brevennia rehi; psyllids in the family Psyllidae such as Diaphorina citri, Trioza erytreae, Cacopsylla pyrisuga, Cacopsylla chinensis, Bactericera cockerelli, Cacopsylla pyricola; lace bugs in the family Tingidae such as Corythucha ciliata, Corythucha marmorata, Stephanitis nashi, Stephanitis pyrioides; bed bugs in the family Cimicidae such as Cimex lectularius, Cimex hemipterus; cicadas in the family Cicadidae such as Quesada gigas;Triatomine bugs such as Triatoma infestans, Triatoma rubrofasciata, Triatoma dimidiata, Rhodnius prolixus, etc. (Reduviidae).;
[0459] Lepidoptera: Crambidae such as Chilo suppressalis, Chilopolychrysus, Scirpophaga innotata, Scirpophaga incertulas, Rupela albina, Cnaphalocrocis medinalis, Marasmiapatnalis, Marasmia exigua, Notarcha derogata, Ostrinia furnacalis, Ostrinia nubilalis, Hellulaundalis, Herpetogramma luctuosale, Pediasiateterrellus, Nymphula depunctalis, Diatraea saccharalis, Leucinodes orbonalis, etc.; Pyralidae such as Elasmopalpuslignosellus, Plodia interpunctella, Euzophera batangensis, Cadra cautella, etc.; Noctuidae such as Spodoptera litura, Spodoptera exigua, Mythimna separata, Mamestrabrassicae, Sesamia inferens, Spodoptera mauritia, Naranga aenescens, Spodoptera frugiperda, Spodopteraexempta, Spodoptera cosmioides, Spodoptera eridania, Agrotis ipsilon, Autographa nigrisigna, Plusiafestucae, Chrysodeixis includens, Trichoplusia spp.) Noctuidae such as Heliothis virescens of the genus Heliothis spp., Helicoverpa armigera, Helicoverpa zea of the genus Helicoverpa spp., Anticarsia gemmatalis, Alabama argillacea, Hopvine borer (Hydraecia immanis); Pieridae such as Pieris rapae; Tortricidae such as Grapholita molesta, Grapholita dimorpha, Leguminivora glycinivorella, Matsumuraeses azukivora, Adoxophyes orana fasciata, Adoxophyes honmai, Homona magnanima, Archips fuscocupreanus, Cydia pomonella, Tetramoera schistaceana, Bean Shoot Borer (Epinotia aporema), Citripestis sagittiferella, Lobesia botrana; Gracillariidae such as Caloptilia theivora, Phyllonorycter ringoniella; Carposinidae such as Carposina sasakii; Lyonetiidae such as Leucoptera coffeella, Lyonetia clerkella, Lyonetia prunifoliella; Lymantria spp. such as Lymantria dispar, Euproctis spp. such as Euproctis pseudoconspersa)such as Lymantriidae; Plutellidae such as Plutella xylostella; Gelechiidae such as Anarsia lineatella, Helcystogramma triannulella, Pectinophora gossypiella, Phthorimaea operculella, Tuta absoluta; Arctiidae such as Hyphantria cunea; Castniidae such as Telchin licus; Cossidae such as Cossus insularis; Geometridae such as Ascotis selenaria; Limacodidae such as Parasa lepida; Stathmopodidae such as Stathmopoda masinissa; Sphingidae such as Acherontia lachesis; Sesiidae such as Nokona feralis, Synanthedon hector, Synanthedon tenuis; Hesperiidae such as Parnara guttata; Tineidae such as Tinea translucens, Tineola bisselliella.
[0460] Thysanoptera: Thripidae such as Frankliniella occidentalis, Thrips palmi, Scirtothrips dorsalis, Thrips tabaci, Frankliniella intonsa, Stenchaetothrips biformis, Echinothrips americanus, Scirtothrips perseae, etc.; Phlaeothripidae such as Haplothrips aculeatus, etc.
[0461] Diptera: Anthomyiidae such as Delia platura, Delia antiqua, Pegomya cunicularia, etc.; Ulidiidae such as Tetanops myopaeformis, etc.; Agromyzidae such as Agromyza oryzae, Liriomyza sativae, Liriomyza trifolii, Chromatomyia horticola, etc.; Chloropidae such as Chlorops oryzae, etc.; Tephritidae such as Bactrocera cucurbitae, Bactrocera dorsalis, Bactrocera latifrons, Bactrocera oleae, Bactrocera tryoni, Ceratitis capitata, Rhagoletis pomonella, Rhacochlaena japonica, etc.; Ephydridae such as Hydrellia griseola, Hydrellia philippina, Hydrellia sasakii, etc.; Drosophilidae such as Drosophila suzukii, Drosophila melanogaster, etc.; Phoridae such as Megaselia spiracularis, etc.; Psychodidae such as Clogmia albipunctata, etc.; Sciaridae such as Bradysia difformis, etc.; Cecidomyiidae such as Mayetiola destructor, Orseolia oryzae, etc.; Diopsidae such as Diopsis macrophthalma, etc.Glossina palpalis, Glossina morsitans, etc. of the family Glossinidae; Simulium japonicum, Simulium damnosum, etc. of the family Simuliidae; the subfamily Phlebotominae; Tipula aino, Tipula oleracea, Tipula paludosa, etc. of the family Tipulidae; Culex pipiens pallens, Culex tritaeniorhynchus, Culex pipiens f. molestus, Culex quinquefasciatus, Culex pipiens pipiens, Culex vishnui, Aedes albopictus, Aedes aegypti, Anopheles sinensis, Anopheles gambiae, Anopheles stephensi, Anopheles coluzzii, Anopheles albimanus, Anopheles sundaicus, Anopheles arabiensis, Anopheles funestus, Anopheles darlingi, Anopheles farauti, Anopheles minimus, etc. of the family Culicidae; Prosimulium yezoensis, Simulium ornatum, etc. of the family Simuliidae; Tabanus trigonus, etc. of the family Tabanidae; Musca domestica, Muscina stabulans, Stomoxys calcitrans, Haematobia irritans, etc. of the family Muscidae; the family Calliphoridae; the family Sarcophagidae;Chironomidae such as Chironomus plumosus, Chironomus yoshimatsui, Glyptotendipes tokunagai, etc.; Fannidae.
[0462] Coleoptera: Diabrotica spp., for example, Diabrotica virgifera virgifera (western corn rootworm), Diabrotica undecimpunctata howardi (southern corn rootworm), Diabrotica barberi (northern corn rootworm), Diabrotica virgifera zeae (Mexican corn rootworm), Diabrotica balteata (banded cucumber beetle), Diabrotica speciosa (South American leaf beetle), Cerotoma trifurcata (bean leaf beetle), Oulema melanopus (cereal leaf beetle), Aulacophora femoralis (yellow melon leaf beetle), Phyllotreta striolata (striped flea beetle), Phyllotreta cruciferae (cabbage flea beetle), Phyllotreta pusilla (western black flea beetle), Psylliodes chrysocephala (rape flea beetle), Psylliodes punctulata (hop flea beetle), Leptinotarsa decemlineata (Colorado potato beetle), Oulema oryzae (rice flea beetle), Colaspis brunnea (grape colaspis), Chaetocnema pulicaria (corn flea beetle), Chaetocnema confinis (sweet potato flea beetle), Epitrix cucumeris (western potato flea beetle), Dicladispa armigera (rice hispa), Myochrous denticollis (southern corn leaf beetle), Laccoptera quadrimaculata (sweet potato tortoise beetle), Epitrix hirtipennis (tobacco flea beetle), etc. of the family Chrysomelidae; Stenolophus lecontei (cornseed carabid), Clivina impressifrons (cornseed carabid), etc. of the family Carabidae; Anomala cuprea (bronze chafer), Anomala rufocuprea (multicolored chafer), Anomala albopilosa (lesser bronze chafer), Popillia japonica (Japanese beetle), Heptophylla picea (soybean chafer), Rhizotrogus majalis (European chafer), Tomarus gibbosus (black round chafer), Holotrichia spp. (japanese beetle genus))、June beetles (Phyllophaga crinita) and other Phyllophaga spp., Argentinean rhinoceros beetles (Diloboderus abderus) and other Diloboderus spp. of the family Scarabaeidae; coffee bean weevils (Araecerus coffeae) and other Anthriibidae; sweet potato weevils (Cylas formicarius) and other Aponidae; bean weevils (Zabrotes subfasciatus) and other Bruchidae; pine shoot beetles (Tomicus piniperda), coffee berry borers (Hypothenemus hampei) and other Scolytidae; sweet potato weevils (Euscepes postfasciatus), alfalfa weevils (Hyperapostica), maize weevils (Sitophilus zeamais), rice weevils (Sitophilus oryzae), granary weevils (Sitophilus granarius), rice water weevils (Lissorhoptrus oryzophilus), palm weevils (Rhabdoscelus lineatocollis), cotton boll weevils (Anthonomus grandis), parasitic granary weevils (Sphenophorus venatus), southern corn billbugs (Sphenophorus callosus), soybean stem weevils (Sternechus subsignatus), sugarcane weevils (Sphenophorus levis), gourd-shaped rust weevils (Scepticus griseus), Scepticus uniformis, Aracanthus mourei and other Aracanthus spp.) Insects of the family Curculionidae such as Eutinobothrus brasiliensis; Insects of the family Tenebrionidae such as Tribolium castaneum, Tribolium confusum, and Alphitobius diaperinus; Insects of the family Coccinellidae such as Epilachna vigintioctopunctata; Insects of the family Bostrychidae such as Lyctus brunneus and Rhizopertha dominica; Insects of the family Ptinidae; Insects of the family Cerambycidae such as Anoplophora malasiaca, Migdolus fryanus, and Aromia bungii; Insects of the family Elateridae such as Melanotus okinawensis, Agriotes fuscicollis, Melanotus legatus, Anchastus spp., Conoderus spp., Ctenicera spp., Limonius spp., and Aeolus spp.; Insects of the family Staphylinidae such as Paederus fuscipes; Insects of the family Dermestidae such as Anthrenus verbasci, Dermestes maculates, and Trogoderma granarium; Insects of the family Anobidae such as Lasioderma serricorne and Stegobium paniceum; Insects of the family Laemophloeidae such as Cryptolestes ferrigineus; Insects of the family Silvanidae such as Oryzaephilus surinamensis; Insects of the family Nitidulidae such as Brassica gethes aeneus.
[0463] Orthoptera: Acrididae such as Locusta migratoria, Dociostaurus maroccanus, Chortoicetes terminifera, Nomadacris septemfasciata, Locustana pardalina, Anacridium melanorhodon, Calliptamus italicus, Melanoplus differentialis, Melanoplus bivittatus, Melanoplus sanguinipes, Melanoplus femurrubrum, Camnula pellucida, Schistocerca gregaria, Gastrimargus musicus, Austracris guttulosa, Oxya yezoensis, Oxya japonica, Patanga succincta, etc.; Gryllotalpidae such as Gryllotalpa orientalis, etc.; Gryllidae such as Acheta domestica, Teleogryllus emma, etc.; Tettigoniidae such as Anabrus simplex, etc.
[0464] Hymenoptera: Tenthredinidae such as Athalia rosae and Athalia japonica; Solenopsis spp. such as Solenopsis invicta and Solenopsis geminata, Atta spp. such as Brown leaf-cutting ant (Attacapiguara), Acromyrmex spp., Paraponera clavata, Ochetellus glaber, Monomorium pharaonis, Linepithema humile, Formica japonica, Pristomyrmex punctutus, Pheidole noda, Pheidole megacephala, Camponotus japonicus, Camponotus obscuripes and other Camponotus spp., Pogonomyrmex occidentalis and other Pogonomyrmex spp., Wasmania auropunctata and other Wasmania spp., Anoplolepis gracilipes and other Formicidae; Vespidae such as Vespa mandarinia, Vespa simillima, Vespa analis, Vespa velutina, Polistes jokahamae; Siricidae such as Urocerus gigas; Bethylidae.
[0465] Order Blattodea: Ectobiidae such as Blattella germanica; Blattidae such as Periplaneta fuliginosa, Periplaneta americana, Periplaneta australasiae, Periplaneta brunnea, Blatta orientalis; Termitidae such as Reticulitermes speratus, Coptotermes formosanus, Incisitermes minor, Cryptotermes domesticus, Odontotermes formosanus, Neotermes koshunensis, Glyptotermes satsumensis, Glyptotermes nakajimai, Glyptotermes fuscus, Hodotermopsis sjostedti, Coptotermes guangzhouensis, Reticulitermes amamianus, Reticulitermes miyatakei, Reticulitermes kanmonensis, Nasutitermes takasagoensis, Pericapritermes nitobei, Sinocapritermes mushae, Cornitermes cumulans.
[0466] Order Siphonaptera: Fleas of the family Pulicidae such as the human flea (Pulex irritans), cat flea (Ctenocephalides felis), dog flea (Ctenocephalides canis), oriental rat flea (Xenopsylla cheopis), and poultry flea (Echidnophaga gallinacea); fleas of the family Hectopsyllidae such as the chigoe flea (Tunga penetrans); fleas of the family Ceratophyllidae such as the European rat flea (Nosopsyllus fasciatus).
[0467] Psocodae: Pediculus humanus capitis and other species of Pediculus, such as Pthirus pubis; Haematopinus eurysternus, Haematopinus suis and other species of Haematopinus; Linognathus vituli, Linognathus ovillus, Solenopotes capillatus and other species of Linognathidae; Bovicola bovis, Bovicola ovis, Bovicola breviceps, Damalinia forficula, Werneckiella spp. and other species of Bovicoliidae; Trichodectes canis, Felicola subrostratus and other species of Trichodectidae; Menopon gallinae, Menacanthus stramineus, Trinoton spp. and other species of Menoponidae; Cummingsia spp. and other species of Trimenoponidae; Trogium pulsatorium and other species of Trogiidae; Liposcelis corrodens, Liposcelis bostrychophila, Liposcelis pearmani, Liposcelis entomophila and other species of Liposcelidae or Liposcelididae.
[0468] Thysanura: Ctenoepisma villosa, Lepisma saccharina and other species of Lepismatidae.
[0469] Order Acari: Tetranychidae including Tetranychus urticae, Tetranychus kanzawai, Tetranychus evansi, Panonychus citri, Panonychus ulmi, Oligonychus spp., etc.; Eriophyidae including Aculops pelekassi, Phyllocoptruta citri, Aculops lycopersici, Calacarus carinatus, Acaphylla theavagrans, Eriophyes chibaensis, Aculus schlechtendali, Aceria diospyri, Aceria tosichella, Shevtchenkella sp., etc.; Tarsonemidae including Polyphagotarsonemus latus, etc.; Tenuipalpidae including Brevipalpus phoenicis, etc.; Tuckerellidae;Hard ticks of the family Ixodidae such as Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis japonica, Haemaphysalis campanulata, Dermacentor variabilis, Dermacentor taiwanensis, Dermacentor andersoni, Dermacentor reticulatus, Ixodes ovatus, Ixodes persulcatus, Ixodes scapularis, Ixodes pacificus, Ixodes holocyclus, Ixodes ricinus, Amblyomma americanum, Amblyomma maculatum, Rhipicephalus microplus, Rhipicephalus annulatus, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, Rhipicephalus decoloratus, etc.; soft ticks of the family Argasidae such as Argas persicus, Ornithodoros hermsi, Ornithodoros turicata, etc.; flour mites of the family Acaridae such as Tyrophagus putrescentiae, Tyrophagus similis, etc.; house dust mites of the family Pyroglyphidae such as Dermatophagoides farinae, Dermatophagoides pteronyssinus, etc.; predatory mites of the family Cheyletidae such as Cheyletus eruditus, Cheyletus malaccensis, Cheyletus moorei, Cheyletiella yasguri, etc.;Psoroptidae such as Psoroptes ovis, Psoroptes equi, Knemidocoptes mutans, Otodectes cynotis, Chorioptes spp.; Sarcoptidae such as Notoedres cati, Notoedres muris, Sarcoptes scabiei; Listrophoridae such as Listrophorus gibbus; Dermanyssidae such as Dermanyssus gallinae; Macronyssidae such as Ornithonyssus sylviarum, Ornithonyssus bacoti, Varroidae such as Varroa jacobsoni, Demodicidae such as Demodex canis, Demodex cati, Trombiculidae such as Leptotrombidium akamushi, Leptotrombidium pallidum, Leptotrombidium scutellare.;
[0470] Order Araneae: Eutichuridae such as Cheiracanthium japonicum; Theridiidae such as Latrodectus hasseltii.
[0471] Order Polydesmida: Paradoxosomatidae such as Oxidus gracilis, Nedyopus tambanus.
[0472] Order Isopoda: Armadillidiidae such as Armadillidium vulgare.
[0473] Chilopoda: Scutigeridae such as Thereuonema hilgendorfi; Scolopendridae such as Scolopendra subspinipes; Ethopolidae such as Bothropolys rugosus.
[0474] Gastropoda: Limacidae such as Limax marginatus and Limax flavus; Philomycidae such as Meghimatium bilineatum; Ampullariidae such as Pomacea canaliculata; Lymnaeidae such as Austropeplea ollula.
[0475] Nematoda: Aphelenchoididae such as Aphelenchoides besseyi; Pratylenchidae such as Pratylenchus coffeae, Pratylenchus brachyurus, Pratylenchus neglectus, Radopholus similis; Heteroderidae such as Meloidogyne javanica, Meloidogyne incognita, Meloidogyne enterolobii, Meloidogyne hapla, Heterodera glycines, Globodera rostochiensis, Globodera pallida; Hoplolaimidae such as Rotylenchulus reniformis; Anguinidae such as Nothotylenchus acris, Ditylenchus dipsaci; Tylenchulidae such as Tylenchulus semipenetrans; Longidoridae such as Xiphinema index; Trichodoridae; Parasitaphelenchidae such as Bursaphelenchus xylophilus.
[0476] Harmful arthropods such as harmful insects and harmful mites, harmful mollusks and harmful nematodes may also be harmful insects, harmful mites and other harmful arthropods, harmful mollusks and harmful nematodes that have reduced drug sensitivity to insecticides, acaricides, molluscicides and nematicides, or have developed drug resistance.
[0477] As a method for controlling harmful arthropods of the present invention, it is carried out by directly applying an effective amount of the compound or composition A of the present invention to harmful arthropods and / or to the habitats of harmful arthropods (plants, soil, indoors of houses, animals, etc.). As a method for controlling harmful arthropods of the present invention, for example, foliage treatment, soil treatment, root treatment, spraying treatment, fumigation treatment, water surface treatment, and seed treatment can be mentioned.
[0478] The compound or composition A of the present invention is usually mixed with inactive carriers such as solid carriers, liquid carriers, gaseous carriers, etc. and surfactants, and formulation adjuvants such as binders, dispersants, stabilizers, etc. are added as needed to prepare aqueous suspension formulations, oily suspension formulations, oil formulations, emulsion formulations, emulsion preparations, microemulsion formulations, microcapsule formulations, wettable powders, water-dispersible powders, powders, granules, tablets, aerosol formulations, resin formulations, etc. It is not limited to these formulations, and it can be formulated into the dosage forms described in Manual on development and use of FAO and WHO Specifications for pesticides, FAO Plant Production and Protection Papers - 271~276, prepared by the FAO / WHO Joint Meeting on Pesticide Specifications, 2016, ISSN: 0259 - 2517.
[0479] These formulations usually contain 0.0001 to 99% by weight of the compound or composition A of the present invention.
[0480] As the solid carrier, for example, clay (pyrophyllite clay, kaolin clay, etc.), talc, calcium carbonate, diatomaceous earth, zeolite, bentonite, acid clay, attapulgite, white carbon, ammonium sulfate, vermiculite, perlite, pumice, silica sand, fine powders and granular materials of chemical fertilizers (ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, ammonium chloride, etc.), and resins (polypropylene, polypropylene, polyester, polyurethane, polyamide, polyvinyl chloride, etc.) can be mentioned.
[0481] Examples of the liquid carrier include water, alcohols (ethanol, cyclohexanol, benzyl alcohol, propylene glycol, polyethylene glycol, etc.), ketones (acetone, cyclohexanone, etc.), aromatic hydrocarbons (xylene, phenylxylene ethane, methylnaphthalene, etc.), aliphatic hydrocarbons (hexane, cyclohexane, etc.), esters (ethyl acetate, methyl oleate, propylene carbonate, etc.), nitriles (acetonitrile, etc.), ethers (ethylene glycol dimethyl ether, etc.), amides (N,N-dimethylformamide, N,N-dimethyloctanamide, etc.), sulfoxides (dimethyl sulfoxide, etc.), lactams (N-methylpyrrolidone, N-octylpyrrolidone, etc.), fatty acids (oleic acid, etc.), and vegetable oils (soybean oil, etc.).
[0482] Examples of the gaseous carrier include fluorocarbons, butane gas, LPG (liquefied petroleum gas), nitrogen, and carbon dioxide.
[0483] Examples of the surfactant include nonionic surfactants (polyoxyethylene alkyl ether, polyoxyethylene alkyl aryl ether, polyethylene glycol fatty acid ester, etc.) and anionic surfactants (alkyl sulfonate, alkyl aryl sulfonate, alkyl sulfate, etc.). Specifically, examples include Nimbus (registered trademark), Assist (registered trademark), Aureo (registered trademark), Iharol (registered trademark), Silwet L-77 (registered trademark), BreakThru (registered trademark), SundanceII (registered trademark), Induce (registered trademark), Penetrator (registered trademark), AgriDex (registered trademark), Lutensol A8 (registered trademark), NP-7 (registered trademark), Triton (registered trademark), Nufilm (registered trademark), Emulgator NP7 (registered trademark), Emulad (registered trademark), TRITON X 45 (registered trademark), AGRAL 90 (registered trademark), AGROTIN (registered trademark), ARPON (registered trademark), EnSpray N (registered trademark), and BANOLE (registered trademark).
[0484] Examples of the other adjuvants for the preparation include binders, dispersants, colorants, and stabilizers, etc. Specifically, examples include polysaccharides (starch, gum arabic, cellulose derivatives, alginic acid, etc.), lignin derivatives, synthetic water-soluble polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyacrylic acids, etc.), isopropyl acid phosphate, and dibutylhydroxytoluene.
[0485] In the present invention, examples of the plant include the whole plant, stems and leaves, flowers, ears, fruits, trunks, branches, crowns, seeds, vegetative propagation organs, and seedlings.
[0486] A vegetative propagation organ refers to an organ in the roots, stems, leaves, etc. of a plant that has the ability to grow when cut from the main body and placed in the soil. As vegetative propagation organs, for example, tuberous roots, creeping roots, bulbs, corms (or solid bulbs), tubers, rhizomes, stolons, rhizophores, cane cuttings, propagules, and vine cuttings can be cited. It should be noted that stolons are sometimes also called runners, and propagules are also called bulbils, which can be divided into broad buds and bulbils. Vine cuttings refer to the sprouts (collectively called shoots of leaves and stems) of sweet potatoes or yams. Bulbs, corms, tubers, rhizomes, cuttings, rhizophores, or tuberous roots are also collectively called bulbous roots. The cultivation of potatoes starts by planting tubers in the soil, and the tubers used are generally called seed potatoes.
[0487] As a method of applying an effective amount of the compound or composition A of the present invention to soil for controlling harmful arthropods, for example, there may be mentioned a method of applying an effective amount of the compound or composition A of the present invention to the soil before or after transplanting a plant, a method of applying an effective amount of the compound or composition A of the present invention to the rhizosphere of a crop that needs to be protected from damage such as feeding by harmful arthropods, and a method of allowing an effective amount of the compound or composition A of the present invention to penetrate and transfer from the roots or the like into the interior of the plant body to control harmful arthropods that feed on the plant. More specifically, for example, there may be mentioned hole treatment (hole spraying, hole treatment soil mixing), root treatment (root spraying, root soil mixing, root irrigation, late-stage root treatment during the seedling raising period), furrow treatment (furrow spraying, furrow soil mixing), ridge furrow treatment (ridge furrow spraying, ridge furrow soil mixing, ridge furrow spraying during the growth period), ridge furrow treatment at sowing time (ridge furrow spraying at sowing time, ridge furrow soil mixing at sowing time), overall treatment (whole soil spraying, whole soil mixing), side treatment of ridge cultivation, water surface treatment (water surface application, water surface application after water storage), other soil spraying treatments (granule foliar spraying during the growth period, spraying under the canopy or around the main trunk, soil surface spraying, soil surface mixing, hole sowing spraying, surface spraying of the ridge part, inter-plant spraying), other irrigation treatments (soil irrigation, irrigation during the seedling raising period, liquid injection treatment, plant base irrigation, drip irrigation of liquid medicine, chemical solution irrigation), seedling box treatment (seedling box spraying, seedling box irrigation, accumulation of liquid medicine in the seedling box), seedling tray treatment (seedling tray spraying, seedling tray irrigation, accumulation of liquid medicine in the seedling tray), seedbed treatment (seedbed spraying, seedbed irrigation, seedbed spraying in the paddy field seedbed, seedling dipping), bed soil mixing treatment (bed soil mixing, bed soil mixing before sowing, spraying before covering soil at sowing time, spraying after covering soil at sowing time, covering soil mixing), and other treatments (cultivated soil mixing, turning in, topsoil mixing, soil mixing at the rain dripping part, planting position treatment, granule flower cluster spraying, paste fertilizer mixing).
[0488] The seed or vegetative propagation organ holding the compound or composition A of the present invention of the present invention refers to a seed or vegetative propagation organ in a state where the compound or composition A of the present invention is attached to the surface of the seed or vegetative propagation organ. In addition, the compound or composition A attached to the surface can penetrate from the surface into the interior.
[0489] In addition, when the composition A is attached to the surface of the seed or vegetative propagation organ, a layer of a single active ingredient may be overlapped multiple times, or it may be a single layer formed by mixing multiple active ingredients, or a layer of a single active ingredient and a layer of multiple active ingredients may be overlapped multiple times, or layers of multiple active ingredients may be overlapped multiple times.
[0490] The seeds or vegetative propagation organs used in seed treatment can be used directly, and in addition, materials other than the compound or composition A of the present invention can be attached before and after treating the compound or composition A of the present invention.
[0491] As a seed treatment, for example, treatment of the seeds or vegetative propagation organs with the compounds or composition A of the present invention can be mentioned. Specifically, for example, a spraying treatment in which a suspension of the compounds or composition A of the present invention is atomized and blown onto the surface of the seeds or vegetative propagation organs, a coating treatment in which the compounds or composition A of the present invention is applied to the seeds or vegetative propagation organs, an immersion treatment in which the seeds or vegetative propagation organs are immersed in a liquid medicine of the compounds or composition A of the present invention for a certain period of time, and a method of coating the seeds or vegetative propagation organs with a carrier containing the compounds or composition A of the present invention (film coating treatment, particle coating treatment, etc.) can be mentioned. As the above-mentioned vegetative propagation organs, seed potatoes can be particularly mentioned.
[0492] When treating seeds or vegetative propagation organs with composition A, composition A can be made into one preparation for treating seeds or vegetative propagation organs, or composition A can be made into different multiple preparations and divided into multiple times for treating seeds or vegetative propagation organs. As a method of making composition A into different multiple preparations and dividing into multiple times for treatment, for example, a method of treating a preparation containing only the compound of the present invention as an active ingredient, air-drying the seeds or vegetative propagation organs, and then treating a preparation containing this ingredient can be mentioned; and a method of treating a preparation containing the compound of the present invention and this ingredient as active ingredients, air-drying the seeds or vegetative propagation organs, and then treating a preparation containing an ingredient other than the ingredient that has been treated can be mentioned.
[0493] Seeds or vegetative propagation organs holding the compound or composition A of the present invention refer to seeds or vegetative propagation organs in a state where the compound or composition A of the present invention adheres to the surface of the seeds or vegetative propagation organs. The above-mentioned seeds or vegetative propagation organs holding the compound or composition A of the present invention can adhere materials other than the compound or composition A of the present invention before or after adhering the compound or composition A of the present invention to the seeds or vegetative propagation organs.
[0494] In addition, when composition A adheres in layers on the surface of seeds or vegetative propagation organs, the layer can be composed of one layer or multiple layers. In addition, when composed of multiple layers, each layer is a layer containing one or more active ingredients, or is composed of a layer containing one or more active ingredients and a layer not containing active ingredients.
[0495] Seeds or vegetative propagation organs holding the compound or composition A of the present invention can be obtained, for example, by applying a preparation containing the compound or composition A of the present invention to the seeds or vegetative propagation organs by using the above-mentioned seed treatment method.
[0496] When using the compound or composition A of the present invention to control harmful arthropods in the agricultural field, the application rate is per 10000 m 2The amount of the compound of the present invention is generally 1 to 10,000 g. When treating seeds or vegetative propagation organs, the amount of the compound of the present invention is generally applied in the range of 0.001 to 100 g relative to 1 Kg of seeds or vegetative propagation organs. When the compound or composition A of the present invention is made into an emulsion, wettable powder, flowable preparation, etc., it is generally diluted with water at an active ingredient concentration of 0.01 to 10,000 ppm for application, and granules, powders, etc. are generally applied directly.
[0497] In addition, the compound or composition A of the present invention can also be treated by methods such as winding resin preparations processed into sheets or lines around crops, laying them near crops, or spreading them on the soil at the roots of plants.
[0498] When the compound or composition A of the present invention is used to control harmful arthropods inhabiting houses, for the application amount, when treating on a plane, based on the amount of the compound of the present invention per 1 m 2 of the treatment area, it is generally 0.01 to 1000 mg, and when treating in a space, based on the amount of the compound of the present invention per 1 m 3 of the treatment space, it is generally 0.01 to 500 mg. When the compound or composition A of the present invention is made into preparations such as emulsions, wettable powders, flowable preparations, etc., it is generally diluted with water at an active ingredient concentration of 0.1 to 10,000 ppm for application, and oil agents, aerosol agents, fumigants, bait agents, etc. are applied directly.
[0499] When the compound or composition A of the present invention is used for controlling external parasites of livestock such as cattle, horses, pigs, sheep, goats, chickens, etc. and small animals such as dogs, cats, rats, mice, etc., it can be used for animals by methods well-known in veterinary medicine. As a specific method of use, in the case of aiming at systemic inhibition, for example, it is administered by tablets, mixing into feed, suppositories, injection (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), and in the case of not aiming at systemic inhibition, for example, by spraying oil agents or aqueous liquid pouring treatment or spraying treatment, washing animals with shampoo preparations, or wearing resin preparations made into collars or ear tags on animals, etc. The amount of the compound of the present invention when administered to animals is generally in the range of 0.1 to 1000 mg relative to 1 kg of the animal's body weight.
[0500] The compound or composition A of the present invention can be used as a control agent for harmful arthropods in agricultural cultivated lands such as dry fields, paddy fields, lawns, orchards, etc. As plants, for example, the following examples can be cited.
[0501] Maize (dent corn, flint corn, soft corn, pop corn, waxy corn, sweet corn, field corn), rice (long-grain rice, short-grain rice, medium-grain rice, japonica rice, tropical japonica rice, indica rice, javanica rice, paddy rice, upland rice, floating rice, direct seeding, transplantation, glutinous rice), wheat (bread wheat (hard, soft, medium, red wheat, white wheat), durum wheat, spelt wheat, club wheat, their respective winter wheat types, spring wheat types), barley (two-row barley (= brewing barley), six-row barley, naked barley, waxy barley, their respective winter barley types, spring barley types), rye (winter rye type, spring rye type), triticale (winter triticale type, spring triticale type), oats (winter oat type, spring oat type), sorghum, cotton (upland cotton, pima cotton), soybeans (mature seed harvest varieties, edamame varieties, immature harvest varieties, their respective indeterminate growth types, determinate growth types, semi-determinate growth types), peanuts, buckwheat, sugar beets (for sugar production, for feed, root vegetables, leaf vegetables, for fuel), rapeseed (winter rapeseed type, spring rapeseed type), canola (winter canola type, spring canola type), sunflowers (for oil extraction, for food, for ornamental purposes), sugarcane, tobacco, tea plants, mulberries, solanaceous vegetables (eggplants, tomatoes, sweet peppers, chili peppers, potatoes, etc.), cucurbitaceous vegetables (cucumbers, pumpkins, zucchinis, watermelons, melons, etc.), cruciferous vegetables (radishes, daikon radishes, horseradish, turnips, Chinese cabbages, cabbages, mustards, broccoli, cauliflower, etc.), asteraceous vegetables (burdocks, spring chrysanthemums, artichokes, lettuces, etc.), liliaceous vegetables (Chinese chives, onions, garlics, asparagus, etc.), umbelliferous vegetables (carrots, parsley, celery, parsnips, etc.), chenopodiaceous vegetables (spinaches, red beets, etc.), labiatae vegetables (perillas, mints, basils, etc.), strawberries, sweet potatoes, yams, taros, pome fruits (apples, pears, Japanese pears, Chinese pears, papayas, quince, etc.), stone fruits (peaches, plums, nectarines, plums, cherries, apricots, prunes, etc.), citrus fruits (oranges, oranges, lemons, limes, grapefruits, etc.), nuts (chestnuts, walnuts, hazelnuts, almonds, pistachios, cashews, macadamias, etc.), berries (blueberries, cranberries, blackberries, raspberries, etc.), grapes, persimmons, figs, olives, loquats, bananas, coffee, dates, coconuts, ornamental plants, forest plants, lawns, forage grasses.
[0502] There are no particular limitations on the above plants as long as they are generally cultivated varieties. The above plants also include plants that can be produced by natural hybridization, plants that can be produced by gene mutation, F1 hybrid plants, and genetically modified crops. As genetically modified crops, for example, those that are Plants resistant to herbicides such as isoxaflutole (an HPPD (4-hydroxyphenylpyruvate dioxygenase) inhibitor), imazethapyr, thifensulfuron-methyl (ALS (acetolactate synthase) inhibitors), EPSP (5-enolpyruvylshikimate-3-phosphate synthase) inhibitors, glutamine synthetase inhibitors, PPO (protoporphyrinogen oxidase) inhibitors, bromoxynil or dicamba; plants capable of synthesizing selective toxins known from Bacillus species such as Bacillus thuringiensis; plants capable of conferring specific insecticidal activity by synthesizing gene fragments partially identical to endogenous genes from harmful insects and inducing gene silencing (RNAi; RNA interference) in the target harmful insects.
[0503] Examples
[0504] Hereinafter, the present invention will be described in more detail based on production examples, formulation examples, test examples, etc., but the present invention is not limited to these examples.
[0505] In this specification, Me represents methyl, Et represents ethyl, iPr represents isopropyl, Bu represents butyl, cPr represents cyclopropyl, and C3F7 represents CF2CF2CF3.
[0506] First, production examples of the compounds of the present invention and their production intermediates are shown.
[0507] When measuring the physical property values of the compounds using liquid chromatography / mass spectrometry (hereinafter referred to as LCMS), the measured molecular ion value [M+H] + or [M-H] - and retention time (hereinafter referred to as RT) are recorded. The conditions for liquid chromatography (hereinafter referred to as LC) are as follows.
[0508] [LC conditions]
[0509] Column: L-column2 ODS, inner diameter 4.6 mm, length 30 mm, particle size 3 μm (Japan Chemical Industry Association)
[0510] UV measurement wavelength: 254 nm
[0511] Mobile phase: Solution A: 0.1% formic acid aqueous solution, Solution B: 0.1% formic acid acetonitrile
[0512] Flow rate: 2.0 mL / minute
[0513] Gradient conditions: Liquid feeding is performed at the concentration gradient described in [Table LC1].
[0514] [Table LC1]
[0515] Time (min) Liquid A (%) Liquid B (%) 0.01 90 10 2.00 0 100 4.00 0 100 4.01 90 10
[0516] Reference Production Example 1
[0517] A mixture of 0.9 g of 3-(bromoacetyl)coumarin, 0.55 g of 2-amino-5-(trifluoromethyl)pyridine and 5 mL of ethanol was stirred under reflux for 8 hours. The resulting mixture was cooled to room temperature, and the precipitated crystals were filtered. The obtained crystals were dried to obtain 0.45 g of Intermediate 1 represented by the following formula.
[0518]
[0519] Intermediate 1: 1 H-NMR(DMSO-D6)δ: 9.36(1H, s), 8.93(1H, s), 8.81(1H, s), 7.98(1H, d), 7.80(1H, d), 7.69 - 7.65(1H, m), 7.57(1H, dd), 7.49(1H, d), 7.43(1H, t).
[0520] Reference Production Example 2
[0521] A mixture of 0.45 g of Intermediate 1, 0.34 g of NIS and 5 mL of DMF was stirred at room temperature for 4 hours. Water was added to the resulting mixture, and the mixture was extracted with ethyl acetate. The obtained organic layer was washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography to obtain 0.2 g of Intermediate 2 represented by the following formula.
[0522]
[0523] Intermediate 2: 1 H-NMR(CDCl3)δ: 8.60(1H, s), 8.18(1H, s), 7.76(1H, d), 7.64 - 7.59(2H, m), 7.44(2H, t), 7.37 - 7.33(1H, m).
[0524] Reference Production Example 3
[0525] To a mixture of 200 g of ethyl 2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]acetate and 800 mL of DMF under ice-cooling, 181.5 g of NIS was added, and the mixture was stirred at room temperature for 40 minutes. The precipitated solid was filtered, and the obtained crystals were washed with water and dried under reduced pressure to obtain a crude product. The crude product was purified by silica gel column chromatography to obtain 237 g of Intermediate 3 represented by the following formula.
[0526]
[0527] Intermediate 3: 1 H-NMR (CDCl3) δ: 1 H-NMR (CDCl3) δ: 8.45 (1H, s), 7.67 (1H, d), 7.39 (1H, dd), 4.21 (2H, q), 3.90 (2H, s), 1.28 (3H, t).
[0528] Reference Production Example 4
[0529] Under a nitrogen atmosphere at 50 °C, 10.2 g of Pd2(dba)3 was added to a mixture of 216 g of Intermediate 3, 12.7 g of Xantphos, 600 mL of 1,4-dioxane, and 100 mL of diisopropylethylamine, and 50 mL of ethanethiol was added dropwise over 30 minutes, followed by stirring for 1 hour. The precipitated solid was filtered, and the resulting solid was washed with 1,4-dioxane and dried under reduced pressure to obtain 140 g of Intermediate 4 represented by the following formula.
[0530]
[0531]
[0532] Intermediate 4: 1 H-NMR (CDCl3) δ: 1 H-NMR (CDCl3) δ: 8.76 (1H, s), 7.70 (1H, d), 7.42 (1H, dd), 4.21 (2H, q), 4.01 (2H, s), 2.72 (2H, q), 1.28 (3H, t), 1.21 (3H, t).
[0532] Reference Production Example 5
[0533] Under ice-cooling, 218 g of mCPBA (purity 70%, containing 30% water) was added to a mixture of 140 g of Intermediate 4 and 700 mL of chloroform, and the mixture was stirred under ice-cooling for 2 hours. The resulting mixture was filtered, and 500 mL of water and 20 g of sodium sulfite were successively added to the filtrate, followed by stirring at room temperature for 30 minutes. 84 g of sodium bicarbonate was added little by little to the resulting mixture and stirred for 30 minutes. The resulting mixture was filtered and liquid-separated. The obtained organic layer was washed successively with saturated aqueous sodium bicarbonate and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to obtain 139.3 g of Intermediate 5 represented by the following formula.
[0534]
[0535] Intermediate 5: 11H-NMR (CDCl3) δ: 1 1H-NMR (CDCl3) δ: 9.22 (1H, s), 7.82 (1H, d), 7.61 (1H, dd), 4.23 (2H, s), 4.22 (2H, q), 3.39 (2H, q), 1.39 (3H, t), 1.30 (3H, t).
[0536] Reference Production Example 6
[0537] A mixture of 5 g of Intermediate 5 and 10 mL of concentrated hydrochloric acid was stirred at 80 °C for 6 hours. After cooling the resulting mixture to room temperature, it was concentrated under reduced pressure. The resulting residue was washed successively with water and chloroform to obtain 4 g of Intermediate 6 represented by the following formula.
[0538]
[0539] Intermediate 6: 1 1H-NMR (CDCl3) δ: 1 1H-NMR (DMSO-D6) δ: 9.08 (1H, s), 8.01 (1H, d), 7.90 (1H, dd), 4.03 (2H, s), 3.58 (2H, q), 1.21 (3H, t).
[0540] Reference Production Example 7
[0541] A mixture of 1.0 g of ethyl 2-(6-bromoimidazo[1,2-a]pyridin-2-yl)acetate, 1.1 g of 2-amino-5-(trifluoromethyl)pyridine, and 3 mL of dimethylformamide dimethyl acetal was stirred at 90 °C for 2 hours. After cooling the resulting mixture to room temperature, it was concentrated under reduced pressure. 1.5 mL of propionic acid was added to the resulting residue, and the mixture was stirred at 120 °C for 1 hour. After cooling the resulting mixture to room temperature, it was neutralized with a saturated aqueous sodium bicarbonate solution. The precipitated solid was filtered, and the resulting solid was washed with methanol and dried under reduced pressure to obtain 0.40 g of Intermediate 7-1 represented by the following formula.
[0542]
[0543] Intermediate 7-1: LCMS: 409 [M+H]+, RT = 2.501 minutes
[0544] Reference Production Example 8
[0545] The compounds produced according to Reference Production Example 7 and their physical property values are shown below.
[0546] In the compound represented by formula (A-1), R cc and R dd are any combination described in [Table A1].
[0547]
[0548] [Table A1]
[0549] Intermediate <![CDATA[R cc > <![CDATA[R dd > 7-2 H <![CDATA[CF3]]> 7-3 Cl H 7-4 I H
[0550] Intermediate 7-3: 1H-NMR (DMSO-D6) δ: 9.33 (1H, s), 9.26 (1H, d), 9.08 (1H, t), 8.73 (1H, s), 8.21 (1H, s), 7.64 (1H, dd), 7.47 (2H, d).
[0551] Intermediate 7-4: 1H-NMR (DMSO-D6) δ: 9.31 (1H, s), 9.24 (1H, d), 8.96 (1H, d), 8.75 (1H, s), 8.19 (1H, s), 7.64 (2H, d), 7.34 - 7.31 (1H, m).
[0552] Production Example 1
[0553] At 50 °C, 0.038 mL of ethanethiol was slowly added dropwise to a mixture of 0.20 g of Intermediate 2, 0.084 mL of diisopropylethylamine, 0.036 g of Pd2(dba3), 0.052 g of Xantphos, and 5 mL of 1,4-dioxane, and the mixture was stirred at 50 °C for 3 hours. After the resulting mixture was cooled to room temperature, it was concentrated under reduced pressure. The residue obtained was purified by silica gel column chromatography (hexane:ethyl acetate = 20:80) to obtain 0.10 g of Compound 1 of the present invention represented by the following formula. Compound 1 of the present invention:
[0554]
[0555] H-NMR (CDCl3) δ: 8.85 (1H, s), 8.13 (1H, s), 7.79 (1H, d), 7.62 - 7.58 (2H, m), 7.48 (1H, dd), 7.42 (1H, d), 7.34 (1H, t), 2.82 (2H, q), 1.20 (3H, t). 1 Production Example 2
[0556]
[0557] To a solution of 0.10 g of Compound 1 of the present invention and 5 mL of chloroform at 0 °C was added 0.14 g of mCPBA (purity 70%, containing 30% water), and the mixture was stirred at room temperature for 1 hour. An aqueous solution of saturated sodium thiosulfate was added to the resulting mixture, and the mixture was extracted with chloroform. The obtained organic layer was washed successively with saturated aqueous sodium hydrogen carbonate and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The obtained residue was purified by silica gel chromatography (ethyl acetate) to obtain 0.1 g of Compound 2 of the present invention represented by the following formula.
[0558]
[0559] Compound 2 of the present invention: 1 H-NMR (CDCl3) δ: 9.25 (1H, s), 8.14 (1H, s), 7.89 (1H, d), 7.67 - 7.60 (3H, m), 7.42 (1H, d), 7.35 (1H, t), 3.73 (2H, q), 1.51 (3H, t).
[0560] Production Example 2-1
[0561] The compounds produced according to Production Example 1 and their physical property values are shown below.
[0562]
[0563] Compound 3 of the present invention: LCMS: 451 [M+H]+, RT = 1.721 minutes
[0564] Production Example 3
[0565] A mixture of 1.0 g of Intermediate 6, 1.0 g of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, 1.2 g of 2-amino-5-(trifluoromethyl)pyridine and 10 mL of pyridine was stirred at 100 °C for 4 hours. After the resulting mixture was cooled to room temperature, it was concentrated under reduced pressure. Saturated brine was added to the resulting residue, and the mixture was extracted with ethyl acetate. The obtained organic layer was washed successively with 5% hydrochloric acid, saturated aqueous sodium hydrogen carbonate and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. 10 mL of N,N-dimethylformamide dimethyl acetal was added to the resulting residue, and the mixture was stirred at 50 °C for 2 hours. Saturated brine was added to the resulting mixture, and the mixture was extracted with ethyl acetate. The obtained organic layer was washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. 12 mL of acetic acid was added to the resulting residue, and the mixture was stirred at room temperature for 1 hour. The resulting mixture was concentrated under reduced pressure, saturated brine was added to the resulting residue, and the mixture was extracted with ethyl acetate. The obtained organic layer was washed successively with saturated aqueous sodium hydrogen carbonate and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The resulting residue was purified by silica gel chromatography (hexane:ethyl acetate = 10:90) to obtain 0.5 g of Compound 4 of the present invention represented by the following formula.
[0566]
[0567] Compound 4 of the present invention: 1 H-NMR (CDCl3) δ: 9.26 (1H, s), 8.18 (1H, s), 8.00 (1H, s), 7.86 (1H, d), 7.68 - 7.65 (2H, m), 7.46 (1H, d), 3.86 (2H, q), 1.50 (3H, t).
[0568] Production Example 3-1
[0569] The compounds produced according to Production Example 3 and their physical property values are shown below.
[0570]
[0571] Compound 9 of the present invention: 1 H-NMR (CDCl3) δ: 1 H-NMR (CDCl3) δ: 9.27 (1H, s), 8.20 (1H, s), 7.86 (1H, d), 7.77 (1H, d), 7.67 - 7.63 (2H, m), 6.97 (1H, dd), 3.88 (2H, q), 1.50 (3H, t).
[0572] Production Example 3-2
[0573] The compounds produced according to Production Example 3 and their physical property values are shown below.
[0574] In the compound represented by formula (A-3), R X , R Y and R Z are combined into a compound of any combination recorded in [Table A3].
[0575]
[0576] [Table A3]
[0577] Compound of the present invention <![CDATA[R x > <![CDATA[R y > <![CDATA[R Z > 10 H Cl H 11 I H H 12 Cl H H 13 H Br H 14 H H Br 15 H H Cl 16 H H <![CDATA[CF3]]>
[0578] Compound 10 of the present invention: 1 H-NMR (CDCl3) δ: 9.26 (1H, s), 8.11 (1H, s), 7.85 (1H, d), 7.64 (1H, dd), 7.59 (1H, d), 7.37 (1H, d), 6.84 (1H, dd), 3.89 (2H, q), 1.50 (3H, t).
[0579] Compound 11 of the present invention: 1 H-NMR (CDCl3) δ: 9.26 (1H, s), 8.06 (1H, s), 7.90 (1H, d), 7.86 (1H, d), 7.69 (1H, dd), 7.64 (1H, dd), 7.16 (1H, d), 3.88 (2H, q), 1.49 (3H, t).
[0580] Compound 12 of the present invention: 1 H-NMR (CDCl3) δ: 9.27 (1H, s), 8.08 (1H, s), 7.86 (1H, d), 7.71 (1H, d), 7.65 (1H, dd), 7.53 (1H, dd), 7.35 (1H, d), 3.89 (2H, q), 1.50 (3H, t).
[0581] Compound 13 of the present invention: 1 H-NMR (CDCl3) δ: 9.26 (1H, s), 8.10 (1H, s), 7.85 (1H, d), 7.64 (1H, dd), 7.58 (1H, d), 7.49 (1H, d), 6.96 (1H, dd), 3.89 (2H, q), 1.50 (3H, t).
[0582] Compound 14 of the present invention: 11H-NMR (CDCl3) δ: 9.27 (1H, s), 8.14 (1H, s), 7.99 (1H, dd), 7.85 (1H, d), 7.65 (2H, dt), 6.75 (1H, t), 3.92 (2H, q), 1.51 (3H, t).
[0583] Compound 15 of the present invention: 1 1H-NMR (CDCl3) δ: 9.26 (1H, s), 8.17 (1H, s), 7.85 (1H, d), 7.77 (1H, dd), 7.66 - 7.61 (2H, m), 6.82 (1H, t), 3.91 (2H, q), 1.50 (3H, t).
[0584] Compound 16 of the present invention: 1 1H-NMR (CDCl3) δ: 9.33 - 9.29 (2H, m), 8.78 (1H, s), 8.23 (1H, d), 7.91 (1H, d), 7.65 (1H, dd), 7.30 (1H, t), 3.79 (2H, q), 1.49 (3H, t).
[0585] Production Example 4
[0586] A mixture of 0.20 g of Intermediate 7-1, 0.24 mL of diethyl disulfide, 0.50 g of iodine, and 5 mL of NMP was stirred at 110 °C for 4 hours. Water was added to the resulting mixture, and the precipitated solid was filtered. 5 mL of chloroform and 0.25 g of mCPBA (purity 70%, containing 30% water) were successively added to the obtained solid, and the mixture was stirred at room temperature for 4 hours. An aqueous sodium thiosulfate solution and a saturated aqueous sodium bicarbonate solution were successively added to the resulting mixture, and the mixture was extracted with chloroform. The obtained organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate = 10:90) to obtain 0.045 g of Compound 5 of the present invention represented by the following formula.
[0587]
[0588] Compound 5 of the present invention: 1 1H-NMR (CDCl3) δ: 9.47 (1H, s), 9.06 (1H, d), 8.73 (1H, s), 7.89 (1H, s), 7.84 (1H, d), 7.69 (1H, d), 7.56 (1H, dd), 3.77 (2H, q), 1.50 (3H, t).
[0589] Production Example 4-1
[0590] The compounds produced according to Production Example 4 and their physical property values are shown below.
[0591] In the compound represented by formula (A-2), R cc and R dd are combined to form a compound of any one of the combinations described in [Table A2].
[0592]
[0593] [Table A2]
[0594] Compound of the present invention <![CDATA[R cc > <![CDATA[R dd > 6 H <![CDATA[CF3]]> 7 Cl H 8 I H
[0595] Compound 6 of the present invention: 1 H-NMR (CDCl3) δ: 9.25 (1H, d), 9.07 (1H, d), 8.77 (1H, t), 8.10 (1H, s), 8.04 (1H, s), 7.35 (1H, d), 7.25 (1H, s), 3.79 (2H, q), 1.48 (3H, t).
[0596] Compound 7 of the present invention: 1 H-NMR (CDCl3) δ: 9.24 (1H, d), 9.15 (1H, s), 8.74 (1H, s), 8.02 (1H, s), 7.69 (1H, dd), 7.57 (1H, d), 7.32 (1H, dd), 3.73 (2H, q), 1.47 (3H, t).
[0597] Compound 8 of the present invention: 1 H-NMR (CDCl3) δ: 9.24 (1H, d), 8.98 (1H, dd), 8.75 (1H, s), 8.02 (1H, t), 7.74 (1H, dd), 7.48 (1H, dd), 7.33 (1H, dd), 3.74 (2H, q), 1.48 (3H, t).
[0598] Next, examples of the compounds of the present invention produced according to either the production examples described in the examples or the production methods described in this specification are shown below.
[0599] In the compound represented by formula (L-1), the symbols n, substituent A 3 , R 6 , R 3b , R 3c and R 1 are combined to form a compound of any one of the combinations described in combination AA (hereinafter, referred to as compound group SX1).
[0600]
[0601] Combination AA is composed of substituent numbers AA1 to AA6930. The substituent numbers AA1 to AA6930 represent the symbols n, substituent A 3 , R 6 , R 3b , R 3c and R 1 's combination, hereinafter denoted as [substituent number; n, A 3 , R 6 , R 3b , R 3c , R 1 . For example, substituent number AA2 means the combination where n is 0, A 3 is CH, R 6 is a hydrogen atom, R 3b is a fluorine atom, R 3c is a hydrogen atom, R 1 is CF3.
[0602] Combination AA: [AA1; 0, CH, H, H, H, CF3], [AA2; 0, CH, H, F, H, CF3], [AA3; 0, CH, H, Cl, H, CF3], [AA4; 0, CH, H, Br, H, CF3], [AA5; 0, CH, H, I, H, CF3], [AA6; 0, CH, H, CF3, H, CF3], [AA7; 0, CH, H, CF2H, H, CF3], [AA8; 0, CH, H, C2F5, H, CF3], [AA9; 0, CH, H, C3F7, H, CF3], [AA10; 0, CH, H, CH2CF3, H, CF3], [AA11; 0, CH, H, CH2CHF2, H, CF3], [AA12; 1, CH, H, H, H, CF3], [AA13; 1, CH, H, F, H, CF3], [AA14; 1, CH, H, Cl, H, CF3], [AA15; 1, CH, H, Br, H, CF3], [AA16; 1, CH, H, I, H, CF3], [AA17; 1, CH, H, CF3, H, CF3], [AA18; 1, CH, H, CF2H, H, CF3], [AA19; 1, CH, H, C2F5, H, CF3], [AA20; 1, CH, H, C3F7, H, CF3], [AA21; 1, CH, H, CH2CF3, H, CF3], [AA22; 1, CH, H, CH2CHF2, H, CF3], [AA23; 2, CH, H, H, H, CF3], [AA24; 2, CH, H, F, H, CF3], [AA25; 2, CH, H, Cl, H, CF3], [AA26; 2, CH, H, Br, H, CF3], [AA27; 2, CH, H, I, H, CF3], [AA28; 2, CH, H, CF3, H, CF3], [AA29; 2, CH, H, CF2H, H, CF3], [AA30; 2, CH, H, C2F5, H, CF3], [AA31; 2, CH, H, C3F7, H, CF3], [AA32; 2, CH, H, CH2CF3, H, CF3], [AA33; 2, CH, H, CH2CHF2, H, CF3], [AA34; 0, N, H, H, H, CF3], [AA35; 0, N, H, F, H, CF3], [AA36; 0, N, H, Cl, H, CF3], [AA37; 0, N, H, Br, H, CF3], [AA38; 0, N, H, I, H, CF3], [AA39; 0, N, H, CF3, H, CF3], [AA40; 0, N, H, CF2H, H, CF3], [AA41; 0, N, H, C2F5, H, CF3], [AA42;[0, N, H, C3F7, H, CF3], [AA43; 0, N, H, CH2CF3, H, CF3], [AA44; 0, N, H, CH2CHF2, H, CF3], [AA45; 1, N, H, H, H, CF3], [AA46; 1, N, H, F, H, CF3], [AA47; 1, N, H, Cl, H, CF3], [AA48; 1, N, H, Br, H, CF3], [AA49; 1, N, H, I, H, CF3], [AA50; 1, N, H, CF3, H, CF3], [AA51; 1, N, H, CF2H, H, CF3], [AA52; 1, N, H, C2F5, H, CF3], [AA53; 1, N, H, C3F7, H, CF3], [AA54; 1, N, H, CH2CF3, H, CF3], [AA55; 1, N, H, CH2CHF2, H, CF3], [AA56; 2, N, H, H, H, CF3], [AA57; 2, N, H, F, H, CF3], [AA58; 2, N, H, Cl, H, CF3], [AA59; 2, N, H, Br, H, CF3], [AA60; 2, N, H, I, H, CF3], [AA61; 2, N, H, CF3, H, CF3], [AA62; 2, N, H, CF2H, H, CF3], [AA63; 2, N, H, C2F5, H, CF3], [AA64; 2, N, H, C3F7, H, CF3], [AA65; 2, N, H, CH2CF3, H, CF3], [AA66; 2, N, H, CH2CHF2, H, CF3], [AA67; 0, CH, Me, H, H, CF3], [AA68; 0, CH, Me, F, H, CF3], [AA69; 0, CH, Me, Cl, H, CF3], [AA70; 0, CH, Me, Br, H, CF3], [AA71; 0, CH, Me, I, H, CF3], [AA72; 0, CH, Me, CF3, H, CF3], [AA73; 0, CH, Me, CF2H, H, CF3], [AA74; 0, CH, Me, C2F5, H, CF3], [AA75; 0, CH, Me, C3F7, H, CF3], [AA76; 0, CH, Me, CH2CF3, H, CF3], [AA77; 0, CH, Me, CH2CHF2, H, CF3], [AA78; 1, CH, Me, H, H, CF3], [AA79; 1, CH, Me, F, H, CF3], [AA80; 1, CH, Me, Cl, H, CF3], [AA81; 1, CH, Me, Br, H, CF3], [AA82; 1, CH, Me, I, H, CF3], [AA83;[1, CH, Me, CF3, H, CF3], [AA84; 1, CH, Me, CF2H, H, CF3], [AA85; 1, CH, Me, C2F5, H, CF3], [AA86; 1, CH, Me, C3F7, H, CF3], [AA87; 1, CH, Me, CH2CF3, H, CF3], [AA88; 1, CH, Me, CH2CHF2, H, CF3], [AA89; 2, CH, Me, H, H, CF3], [AA90; 2, CH, Me, F, H, CF3], [AA91; 2, CH, Me, Cl, H, CF3], [AA92; 2, CH, Me, Br, H, CF3], [AA93; 2, CH, Me, I, H, CF3], [AA94; 2, CH, Me, CF3, H, CF3], [AA95; 2, CH, Me, CF2H, H, CF3], [AA96; 2, CH, Me, C2F5, H, CF3], [AA97; 2, CH, Me, C3F7, H, CF3], [AA98; 2, CH, Me, CH2CF3, H, CF3], [AA99; 2, CH, Me, CH2CHF2, H, CF3], [AA100; 0, N, Me, H, H, CF3], [AA101; 0, N, Me, F, H, CF3], [AA102; 0, N, Me, Cl, H, CF3], [AA103; 0, N, Me, Br, H, CF3], [AA104; 0, N, Me, I, H, CF3], [AA105; 0, N, Me, CF3, H, CF3], [AA106; 0, N, Me, CF2H, H, CF3], [AA107; 0, N, Me, C2F5, H, CF3], [AA108; 0, N, Me, C3F7, H, CF3], [AA109; 0, N, Me, CH2CF3, H, CF3], [AA110; 0, N, Me, CH2CHF2, H, CF3], [AA111; 1, N, Me, H, H, CF3], [AA112; 1, N, Me, F, H, CF3], [AA113; 1, N, Me, Cl, H, CF3], [AA114; 1, N, Me, Br, H, CF3], [AA115; 1, N, Me, I, H, CF3], [AA116; 1, N, Me, CF3, H, CF3], [AA117; 1, N, Me, CF2H, H, CF3], [AA118; 1, N, Me, C2F5, H, CF3], [AA119; 1, N, Me, C3F7, H, CF3], [AA120; 1, N, Me, CH2CF3, H, CF3], [AA121; 1, N, Me, CH2CHF2, H, CF3], [AA122;[2,N,Me,H,H,CF3], [AA123; 2,N,Me,F,H,CF3], [AA124; 2,N,Me,Cl,H,CF3], [AA125; 2,N,Me,Br,H,CF3], [AA126; 2,N,Me,I,H,CF3], [AA127; 2,N,Me,CF3,H,CF3], [AA128; 2,N,Me,CF2H,H,CF3], [AA129; 2,N,Me,C2F5,H,CF3], [AA130; 2,N,Me,C3F7,H,CF3], [AA131; 2,N,Me,CH2CF3,H,CF3], [AA132; 2,N,Me,CH2CHF2,H,CF3], [AA133; 0,CH,Et,H,H,CF3], [AA134; 0,CH,Et,F,H,CF3], [AA135; 0,CH,Et,Cl,H,CF3], [AA136; 0,CH,Et,Br,H,CF3], [AA137; 0,CH,Et,I,H,CF3], [AA138; 0,CH,Et,CF3,H,CF3], [AA139; 0,CH,Et,CF2H,H,CF3], [AA140; 0,CH,Et,C2F5,H,CF3], [AA141; 0,CH,Et,C3F7,H,CF3], [AA142; 0,CH,Et,CH2CF3,H,CF3], [AA143; 0,CH,Et,CH2CHF2,H,CF3], [AA144; 1,CH,Et,H,H,CF3], [AA145; 1,CH,Et,F,H,CF3], [AA146; 1,CH,Et,Cl,H,CF3], [AA147; 1,CH,Et,Br,H,CF3], [AA148; 1,CH,Et,I,H,CF3], [AA149; 1,CH,Et,CF3,H,CF3], [AA150; 1,CH,Et,CF2H,H,CF3], [AA151; 1,CH,Et,C2F5,H,CF3], [AA152; 1,CH,Et,C3F7,H,CF3], [AA153; 1,CH,Et,CH2CF3,H,CF3], [AA154; 1,CH,Et,CH2CHF2,H,CF3], [AA155; 2,CH,Et,H,H,CF3], [AA156; 2,CH,Et,F,H,CF3], [AA157; 2,CH,Et,Cl,H,CF3], [AA158; 2,CH,Et,Br,H,CF3], [AA159; 2,CH,Et,I,H,CF3], [AA160; 2,CH,Et,CF3,H,CF3], [AA161;[2, CH, Et, CF2H, H, CF3], [AA162; 2, CH, Et, C2F5, H, CF3], [AA163; 2, CH, Et, C3F7, H, CF3], [AA164; 2, CH, Et, CH2CF3, H, CF3], [AA165; 2, CH, Et, CH2CHF2, H, CF3], [AA166; 0, N, Et, H, H, CF3], [AA167; 0, N, Et, F, H, CF3], [AA168; 0, N, Et, Cl, H, CF3], [AA169; 0, N, Et, Br, H, CF3], [AA170; 0, N, Et, I, H, CF3], [AA171; 0, N, Et, CF3, H, CF3], [AA172; 0, N, Et, CF2H, H, CF3], [AA173; 0, N, Et, C2F5, H, CF3], [AA174; 0, N, Et, C3F7, H, CF3], [AA175; 0, N, Et, CH2CF3, H, CF3], [AA176; 0, N, Et, CH2CHF2, H, CF3], [AA177; 1, N, Et, H, H, CF3], [AA178; 1, N, Et, F, H, CF3], [AA179; 1, N, Et, Cl, H, CF3], [AA180; 1, N, Et, Br, H, CF3], [AA181; 1, N, Et, I, H, CF3], [AA182; 1, N, Et, CF3, H, CF3], [AA183; 1, N, Et, CF2H, H, CF3], [AA184; 1, N, Et, C2F5, H, CF3], [AA185; 1, N, Et, C3F7, H, CF3], [AA186; 1, N, Et, CH2CF3, H, CF3], [AA187; 1, N, Et, CH2CHF2, H, CF3], [AA188; 2, N, Et, H, H, CF3], [AA189; 2, N, Et, F, H, CF3], [AA190; 2, N, Et, Cl, H, CF3], [AA191; 2, N, Et, Br, H, CF3], [AA192; 2, N, Et, I, H, CF3], [AA193; 2, N, Et, CF3, H, CF3], [AA194; 2, N, Et, CF2H, H, CF3], [AA195; 2, N, Et, C2F5, H, CF3], [AA196; 2, N, Et, C3F7, H, CF3], [AA197; 2, N, Et, CH2CF3, H, CF3], [AA198; 2, N, Et, CH2CHF2, H, CF3], [AA199; 0, CH, iPr, H, H, CF3], [AA200;[0, CH, iPr, F, H, CF3], [AA201; 0, CH, iPr, Cl, H, CF3], [AA202; 0, CH, iPr, Br, H, CF3], [AA203; 0, CH, iPr, I, H, CF3], [AA204; 0, CH, iPr, CF3, H, CF3], [AA205; 0, CH, iPr, CF2H, H, CF3], [AA206; 0, CH, iPr, C2F5, H, CF3], [AA207; 0, CH, iPr, C3F7, H, CF3], [AA208; 0, CH, iPr, CH2CF3, H, CF3], [AA209; 0, CH, iPr, CH2CHF2, H, CF3], [AA210; 1, CH, iPr, H, H, CF3], [AA211; 1, CH, iPr, F, H, CF3], [AA212; 1, CH, iPr, Cl, H, CF3], [AA213; 1, CH, iPr, Br, H, CF3], [AA214; 1, CH, iPr, I, H, CF3], [AA215; 1, CH, iPr, CF3, H, CF3], [AA216; 1, CH, iPr, CF2H, H, CF3], [AA217; 1, CH, iPr, C2F5, H, CF3], [AA218; 1, CH, iPr, C3F7, H, CF3], [AA219; 1, CH, iPr, CH2CF3, H, CF3], [AA220; 1, CH, iPr, CH2CHF2, H, CF3], [AA221; 2, CH, iPr, H, H, CF3], [AA222; 2, CH, iPr, F, H, CF3], [AA223; 2, CH, iPr, Cl, H, CF3], [AA224; 2, CH, iPr, Br, H, CF3], [AA225; 2, CH, iPr, I, H, CF3], [AA226; 2, CH, iPr, CF3, H, CF3], [AA227; 2, CH, iPr, CF2H, H, CF3], [AA228; 2, CH, iPr, C2F5, H, CF3], [AA229; 2, CH, iPr, C3F7, H, CF3], [AA230; 2, CH, iPr, CH2CF3, H, CF3], [AA231; 2, CH, iPr, CH2CHF2, H, CF3], [AA232; 0, N, iPr, H, H, CF3], [AA233; 0, N, iPr, F, H, CF3], [AA234; 0, N, iPr, Cl, H, CF3], [AA235; 0, N, iPr, Br, H, CF3], [AA236; 0, N, iPr, I, H, CF3], [AA237;[0, N, iPr, CF3, H, CF3], [AA238; 0, N, iPr, CF2H, H, CF3], [AA239; 0, N, iPr, C2F5, H, CF3], [AA240; 0, N, iPr, C3F7, H, CF3], [AA241; 0, N, iPr, CH2CF3, H, CF3], [AA242; 0, N, iPr, CH2CHF2, H, CF3], [AA243; 1, N, iPr, H, H, CF3], [AA244; 1, N, iPr, F, H, CF3], [AA245; 1, N, iPr, Cl, H, CF3], [AA246; 1, N, iPr, Br, H, CF3], [AA247; 1, N, iPr, I, H, CF3], [AA248; 1, N, iPr, CF3, H, CF3], [AA249; 1, N, iPr, CF2H, H, CF3], [AA250; 1, N, iPr, C2F5, H, CF3], [AA251; 1, N, iPr, C3F7, H, CF3], [AA252; 1, N, iPr, CH2CF3, H, CF3], [AA253; 1, N, iPr, CH2CHF2, H, CF3], [AA254; 2, N, iPr, H, H, CF3], [AA255; 2, N, iPr, F, H, CF3], [AA256; 2, N, iPr, Cl, H, CF3], [AA257; 2, N, iPr, Br, H, CF3], [AA258; 2, N, iPr, I, H, CF3], [AA259; 2, N, iPr, CF3, H, CF3], [AA260; 2, N, iPr, CF2H, H, CF3], [AA261; 2, N, iPr, C2F5, H, CF3], [AA262; 2, N, iPr, C3F7, H, CF3], [AA263; 2, N, iPr, CH2CF3, H, CF3], [AA264; 2, N, iPr, CH2CHF2, H, CF3], [AA265; 0, CH, cPr, H, H, CF3], [AA266; 0, CH, cPr, F, H, CF3], [AA267; 0, CH, cPr, Cl, H, CF3], [AA268; 0, CH, cPr, Br, H, CF3], [AA269; 0, CH, cPr, I, H, CF3], [AA270; 0, CH, cPr, CF3, H, CF3], [AA271; 0, CH, cPr, CF2H, H, CF3], [AA272; 0, CH, cPr, C2F5, H, CF3], [AA273; 0, CH, cPr, C3F7, H, CF3], [AA274;[0, CH, cPr, CH2CF3, H, CF3], [AA275; 0, CH, cPr, CH2CHF2, H, CF3], [AA276; 1, CH, cPr, H, H, CF3], [AA277; 1, CH, cPr, F, H, CF3], [AA278; 1, CH, cPr, Cl, H, CF3], [AA279; 1, CH, cPr, Br, H, CF3], [AA280; 1, CH, cPr, I, H, CF3], [AA281; 1, CH, cPr, CF3, H, CF3], [AA282; 1, CH, cPr, CF2H, H, CF3], [AA283; 1, CH, cPr, C2F5, H, CF3], [AA284; 1, CH, cPr, C3F7, H, CF3], [AA285; 1, CH, cPr, CH2CF3, H, CF3], [AA286; 1, CH, cPr, CH2CHF2, H, CF3], [AA287; 2, CH, cPr, H, H, CF3], [AA288; 2, CH, cPr, F, H, CF3], [AA289; 2, CH, cPr, Cl, H, CF3], [AA290; 2, CH, cPr, Br, H, CF3], [AA291; 2, CH, cPr, I, H, CF3], [AA292; 2, CH, cPr, CF3, H, CF3], [AA293; 2, CH, cPr, CF2H, H, CF3], [AA294; 2, CH, cPr, C2F5, H, CF3], [AA295; 2, CH, cPr, C3F7, H, CF3], [AA296; 2, CH, cPr, CH2CF3, H, CF3], [AA297; 2, CH, cPr, CH2CHF2, H, CF3], [AA298; 0, N, cPr, H, H, CF3], [AA299; 0, N, cPr, F, H, CF3], [AA300; 0, N, cPr, Cl, H, CF3], [AA301; 0, N, cPr, Br, H, CF3], [AA302; 0, N, cPr, I, H, CF3], [AA303; 0, N, cPr, CF3, H, CF3], [AA304; 0, N, cPr, CF2H, H, CF3], [AA305; 0, N, cPr, C2F5, H, CF3], [AA306; 0, N, cPr, C3F7, H, CF3], [AA307; 0, N, cPr, CH2CF3, H, CF3], [AA308; 0, N, cPr, CH2CHF2, H, CF3], [AA309; 1, N, cPr, H, H, CF3], [AA310; 1, N, cPr, F, H, CF3], [AA311;[1,N,cPr,Cl,H,CF3], [AA312; 1,N,cPr,Br,H,CF3], [AA313; 1,N,cPr,I,H,CF3], [AA314; 1,N,cPr,CF3,H,CF3], [AA315; 1,N,cPr,CF2H,H,CF3], [AA316; 1,N,cPr,C2F5,H,CF3], [AA317; 1,N,cPr,C3F7,H,CF3], [AA318; 1,N,cPr,CH2CF3,H,CF3], [AA319; 1,N,cPr,CH2CHF2,H,CF3], [AA320; 2,N,cPr,H,H,CF3], [AA321; 2,N,cPr,F,H,CF3], [AA322; 2,N,cPr,Cl,H,CF3], [AA323; 2,N,cPr,Br,H,CF3], [AA324; 2,N,cPr,I,H,CF3], [AA325; 2,N,cPr,CF3,H,CF3], [AA326; 2,N,cPr,CF2H,H,CF3], [AA327; 2,N,cPr,C2F5,H,CF3], [AA328; 2,N,cPr,C3F7,H,CF3], [AA329; 2,N,cPr,CH2CF3,H,CF3], [AA330; 2,N,cPr,CH2CHF2,H,CF3], [AA331; 0,CH,H,H,F,CF3], [AA332; 0,CH,H,H,Cl,CF3], [AA333; 0,CH,H,H,Br,CF3], [AA334; 0,CH,H,H,I,CF3], [AA335; 0,CH,H,H,CF3,CF3], [AA336; 0,CH,H,H,CF2H,CF3], [AA337; 0,CH,H,H,C2F5,CF3], [AA338; 0,CH,H,H,C3F7,CF3], [AA339; 0,CH,H,H,CH2CF3,CF3], [AA340; 0,CH,H,H,CH2CHF2,CF3], [AA341; 1,CH,H,H,F,CF3], [AA342; 1,CH,H,H,Cl,CF3], [AA343; 1,CH,H,H,Br,CF3], [AA344; 1,CH,H,H,I,CF3], [AA345; 1,CH,H,H,CF3,CF3], [AA346; 1,CH,H,H,CF2H,CF3], [AA347; 1,CH,H,H,C2F5,CF3], [AA348; 1,CH,H,H,C3F7,CF3], [AA349;1,CH,H,H,CH2CF3,CF3], [AA350; 1,CH,H,H,CH2CHF2,CF3], [AA351; 2,CH,H,H,F,CF3], [AA352; 2,CH,H,H,Cl,CF3], [AA353; 2,CH,H,H,Br,CF3], [AA354; 2,CH,H,H,I,CF3], [AA355; 2,CH,H,H,CF3,CF3], [AA356; 2,CH,H,H,CF2H,CF3], [AA357; 2,CH,H,H,C2F5,CF3], [AA358; 2,CH,H,H,C3F7,CF3], [AA359; 2,CH,H,H,CH2CF3,CF3], [AA360; 2,CH,H,H,CH2CHF2,CF3], [AA361; 0,N,H,H,F,CF3], [AA362; 0,N,H,H,Cl,CF3], [AA363; 0,N,H,H,Br,CF3], [AA364; 0,N,H,H,I,CF3], [AA365; 0,N,H,H,CF3,CF3], [AA366; 0,N,H,H,CF2H,CF3], [AA367; 0,N,H,H,C2F5,CF3], [AA368; 0,N,H,H,C3F7,CF3], [AA369; 0,N,H,H,CH2CF3,CF3], [AA370; 0,N,H,H,CH2CHF2,CF3], [AA371; 1,N,H,H,F,CF3], [AA372; 1,N,H,H,Cl,CF3], [AA373; 1,N,H,H,Br,CF3], [AA374; 1,N,H,H,I,CF3], [AA375; 1,N,H,H,CF3,CF3], [AA376; 1,N,H,H,CF2H,CF3], [AA377; 1,N,H,H,C2F5,CF3], [AA378; 1,N,H,H,C3F7,CF3], [AA379; 1,N,H,H,CH2CF3,CF3], [AA380; 1,N,H,H,CH2CHF2,CF3], [AA381; 2,N,H,H,F,CF3], [AA382; 2,N,H,H,Cl,CF3], [AA383; 2,N,H,H,Br,CF3], [AA384; 2,N,H,H,I,CF3], [AA385; 2,N,H,H,CF3,CF3], [AA386; 2,N,H,H,CF2H,CF3], [AA387; 2,N,H,H,C2F5,CF3], [AA388; 2,N,H,H,C3F7,CF3], [AA389;[2,N,H,H,CH2CF3,CF3], [AA390; 2,N,H,H,CH2CHF2,CF3], [AA391; 0,CH,Me,H,F,CF3], [AA392; 0,CH,Me,H,Cl,CF3], [AA393; 0,CH,Me,H,Br,CF3], [AA394; 0,CH,Me,H,I,CF3], [AA395; 0,CH,Me,H,CF3,CF3], [AA396; 0,CH,Me,H,CF2H,CF3], [AA397; 0,CH,Me,H,C2F5,CF3], [AA398; 0,CH,Me,H,C3F7,CF3], [AA399; 0,CH,Me,H,CH2CF3,CF3], [AA400; 0,CH,Me,H,CH2CHF2,CF3], [AA401; 1,CH,Me,H,F,CF3], [AA402; 1,CH,Me,H,Cl,CF3], [AA403; 1,CH,Me,H,Br,CF3], [AA404; 1,CH,Me,H,I,CF3], [AA405; 1,CH,Me,H,CF3,CF3], [AA406; 1,CH,Me,H,CF2H,CF3], [AA407; 1,CH,Me,H,C2F5,CF3], [AA408; 1,CH,Me,H,C3F7,CF3], [AA409; 1,CH,Me,H,CH2CF3,CF3], [AA410; 1,CH,Me,H,CH2CHF2,CF3], [AA411; 2,CH,Me,H,F,CF3], [AA412; 2,CH,Me,H,Cl,CF3], [AA413; 2,CH,Me,H,Br,CF3], [AA414; 2,CH,Me,H,I,CF3], [AA415; 2,CH,Me,H,CF3,CF3], [AA416; 2,CH,Me,H,CF2H,CF3], [AA417; 2,CH,Me,H,C2F5,CF3], [AA418; 2,CH,Me,H,C3F7,CF3], [AA419; 2,CH,Me,H,CH2CF3,CF3], [AA420; 2,CH,Me,H,CH2CHF2,CF3], [AA421; 0,N,Me,H,F,CF3], [AA422; 0,N,Me,H,Cl,CF3], [AA423; 0,N,Me,H,Br,CF3], [AA424; 0,N,Me,H,I,CF3], [AA425; 0,N,Me,H,CF3,CF3], [AA426; 0,N,Me,H,CF2H,CF3], [AA427;[0, N, Me, H, C2F5, CF3], [AA428; 0, N, Me, H, C3F7, CF3], [AA429; 0, N, Me, H, CH2CF3, CF3], [AA430; 0, N, Me, H, CH2CHF2, CF3], [AA431; 1, N, Me, H, F, CF3], [AA432; 1, N, Me, H, Cl, CF3], [AA433; 1, N, Me, H, Br, CF3], [AA434; 1, N, Me, H, I, CF3], [AA435; 1, N, Me, H, CF3, CF3], [AA436; 1, N, Me, H, CF2H, CF3], [AA437; 1, N, Me, H, C2F5, CF3], [AA438; 1, N, Me, H, C3F7, CF3], [AA439; 1, N, Me, H, CH2CF3, CF3], [AA440; 1, N, Me, H, CH2CHF2, CF3], [AA441; 2, N, Me, H, F, CF3], [AA442; 2, N, Me, H, Cl, CF3], [AA443; 2, N, Me, H, Br, CF3], [AA444; 2, N, Me, H, I, CF3], [AA445; 2, N, Me, H, CF3, CF3], [AA446; 2, N, Me, H, CF2H, CF3], [AA447; 2, N, Me, H, C2F5, CF3], [AA448; 2, N, Me, H, C3F7, CF3], [AA449; 2, N, Me, H, CH2CF3, CF3], [AA450; 2, N, Me, H, CH2CHF2, CF3], [AA451; 0, CH, Et, H, F, CF3], [AA452; 0, CH, Et, H, Cl, CF3], [AA453; 0, CH, Et, H, Br, CF3], [AA454; 0, CH, Et, H, I, CF3], [AA455; 0, CH, Et, H, CF3, CF3], [AA456; 0, CH, Et, H, CF2H, CF3], [AA457; 0, CH, Et, H, C2F5, CF3], [AA458; 0, CH, Et, H, C3F7, CF3], [AA459; 0, CH, Et, H, CH2CF3, CF3], [AA460; 0, CH, Et, H, CH2CHF2, CF3], [AA461; 1, CH, Et, H, F, CF3], [AA462; 1, CH, Et, H, Cl, CF3], [AA463; 1, CH, Et, H, Br, CF3], [AA464; 1, CH, Et, H, I, CF3], [AA465;[1, CH, Et, H, CF3, CF3], [AA466; 1, CH, Et, H, CF2H, CF3], [AA467; 1, CH, Et, H, C2F5, CF3], [AA468; 1, CH, Et, H, C3F7, CF3], [AA469; 1, CH, Et, H, CH2CF3, CF3], [AA470; 1, CH, Et, H, CH2CHF2, CF3], [AA471; 2, CH, Et, H, F, CF3], [AA472; 2, CH, Et, H, Cl, CF3], [AA473; 2, CH, Et, H, Br, CF3], [AA474; 2, CH, Et, H, I, CF3], [AA475; 2, CH, Et, H, CF3, CF3], [AA476; 2, CH, Et, H, CF2H, CF3], [AA477; 2, CH, Et, H, C2F5, CF3], [AA478; 2, CH, Et, H, C3F7, CF3], [AA479; 2, CH, Et, H, CH2CF3, CF3], [AA480; 2, CH, Et, H, CH2CHF2, CF3], [AA481; 0, N, Et, H, F, CF3], [AA482; 0, N, Et, H, Cl, CF3], [AA483; 0, N, Et, H, Br, CF3], [AA484; 0, N, Et, H, I, CF3], [AA485; 0, N, Et, H, CF3, CF3], [AA486; 0, N, Et, H, CF2H, CF3], [AA487; 0, N, Et, H, C2F5, CF3], [AA488; 0, N, Et, H, C3F7, CF3], [AA489; 0, N, Et, H, CH2CF3, CF3], [AA490; 0, N, Et, H, CH2CHF2, CF3], [AA491; 1, N, Et, H, F, CF3], [AA492; 1, N, Et, H, Cl, CF3], [AA493; 1, N, Et, H, Br, CF3], [AA494; 1, N, Et, H, I, CF3], [AA495; 1, N, Et, H, CF3, CF3], [AA496; 1, N, Et, H, CF2H, CF3], [AA497; 1, N, Et, H, C2F5, CF3], [AA498; 1, N, Et, H, C3F7, CF3], [AA499; 1, N, Et, H, CH2CF3, CF3], [AA500; 1, N, Et, H, CH2CHF2, CF3], [AA501; 2, N, Et, H, F, CF3], [AA502; 2, N, Et, H, Cl, CF3], [AA503;[2,N,Et,H,Br,CF3], [AA504; 2,N,Et,H,I,CF3], [AA505; 2,N,Et,H,CF3,CF3], [AA506; 2,N,Et,H,CF2H,CF3], [AA507; 2,N,Et,H,C2F5,CF3], [AA508; 2,N,Et,H,C3F7,CF3], [AA509; 2,N,Et,H,CH2CF3,CF3], [AA510; 2,N,Et,H,CH2CHF2,CF3], [AA511; 0,CH,iPr,H,F,CF3], [AA512; 0,CH,iPr,H,Cl,CF3], [AA513; 0,CH,iPr,H,Br,CF3], [AA514; 0,CH,iPr,H,I,CF3], [AA515; 0,CH,iPr,H,CF3,CF3], [AA516; 0,CH,iPr,H,CF2H,CF3], [AA517; 0,CH,iPr,H,C2F5,CF3], [AA518; 0,CH,iPr,H,C3F7,CF3], [AA519; 0,CH,iPr,H,CH2CF3,CF3], [AA520; 0,CH,iPr,H,CH2CHF2,CF3], [AA521; 1,CH,iPr,H,F,CF3], [AA522; 1,CH,iPr,H,Cl,CF3], [AA523; 1,CH,iPr,H,Br,CF3], [AA524; 1,CH,iPr,H,I,CF3], [AA525; 1,CH,iPr,H,CF3,CF3], [AA526; 1,CH,iPr,H,CF2H,CF3], [AA527; 1,CH,iPr,H,C2F5,CF3], [AA528; 1,CH,iPr,H,C3F7,CF3], [AA529; 1,CH,iPr,H,CH2CF3,CF3], [AA530; 1,CH,iPr,H,CH2CHF2,CF3], [AA531; 2,CH,iPr,H,F,CF3], [AA532; 2,CH,iPr,H,Cl,CF3], [AA533; 2,CH,iPr,H,Br,CF3], [AA534; 2,CH,iPr,H,I,CF3], [AA535; 2,CH,iPr,H,CF3,CF3], [AA536; 2,CH,iPr,H,CF2H,CF3], [AA537; 2,CH,iPr,H,C2F5,CF3], [AA538; 2,CH,iPr,H,C3F7,CF3], [AA539; 2,CH,iPr,H,CH2CF3,CF3], [AA540;[2,CH,iPr,H,CH2CHF2,CF3], [AA541; 0,N,iPr,H,F,CF3], [AA542; 0,N,iPr,H,Cl,CF3], [AA543; 0,N,iPr,H,Br,CF3], [AA544; 0,N,iPr,H,I,CF3], [AA545; 0,N,iPr,H,CF3,CF3], [AA546; 0,N,iPr,H,CF2H,CF3], [AA547; 0,N,iPr,H,C2F5,CF3], [AA548; 0,N,iPr,H,C3F7,CF3], [AA549; 0,N,iPr,H,CH2CF3,CF3], [AA550; 0,N,iPr,H,CH2CHF2,CF3], [AA551; 1,N,iPr,H,F,CF3], [AA552; 1,N,iPr,H,Cl,CF3], [AA553; 1,N,iPr,H,Br,CF3], [AA554; 1,N,iPr,H,I,CF3], [AA555; 1,N,iPr,H,CF3,CF3], [AA556; 1,N,iPr,H,CF2H,CF3], [AA557; 1,N,iPr,H,C2F5,CF3], [AA558; 1,N,iPr,H,C3F7,CF3], [AA559; 1,N,iPr,H,CH2CF3,CF3], [AA560; 1,N,iPr,H,CH2CHF2,CF3], [AA561; 2,N,iPr,H,F,CF3], [AA562; 2,N,iPr,H,Cl,CF3], [AA563; 2,N,iPr,H,Br,CF3], [AA564; 2,N,iPr,H,I,CF3], [AA565; 2,N,iPr,H,CF3,CF3], [AA566; 2,N,iPr,H,CF2H,CF3], [AA567; 2,N,iPr,H,C2F5,CF3], [AA568; 2,N,iPr,H,C3F7,CF3], [AA569; 2,N,iPr,H,CH2CF3,CF3], [AA570; 2,N,iPr,H,CH2CHF2,CF3], [AA571; 0,CH,cPr,H,F,CF3], [AA572; 0,CH,cPr,H,Cl,CF3], [AA573; 0,CH,cPr,H,Br,CF3], [AA574; 0,CH,cPr,H,I,CF3], [AA575; 0,CH,cPr,H,CF3,CF3], [AA576; 0,CH,cPr,H,CF2H,CF3], [AA577;[0, CH, cPr, H, C2F5, CF3], [AA578; 0, CH, cPr, H, C3F7, CF3], [AA579; 0, CH, cPr, H, CH2CF3, CF3], [AA580; 0, CH, cPr, H, CH2CHF2, CF3], [AA581; 1, CH, cPr, H, F, CF3], [AA582; 1, CH, cPr, H, Cl, CF3], [AA583; 1, CH, cPr, H, Br, CF3], [AA584; 1, CH, cPr, H, I, CF3], [AA585; 1, CH, cPr, H, CF3, CF3], [AA586; 1, CH, cPr, H, CF2H, CF3], [AA587; 1, CH, cPr, H, C2F5, CF3], [AA588; 1, CH, cPr, H, C3F7, CF3], [AA589; 1, CH, cPr, H, CH2CF3, CF3], [AA590; 1, CH, cPr, H, CH2CHF2, CF3], [AA591; 2, CH, cPr, H, F, CF3], [AA592; 2, CH, cPr, H, Cl, CF3], [AA593; 2, CH, cPr, H, Br, CF3], [AA594; 2, CH, cPr, H, I, CF3], [AA595; 2, CH, cPr, H, CF3, CF3], [AA596; 2, CH, cPr, H, CF2H, CF3], [AA597; 2, CH, cPr, H, C2F5, CF3], [AA598; 2, CH, cPr, H, C3F7, CF3], [AA599; 2, CH, cPr, H, CH2CF3, CF3], [AA600; 2, CH, cPr, H, CH2CHF2, CF3], [AA601; 0, N, cPr, H, F, CF3], [AA602; 0, N, cPr, H, Cl, CF3], [AA603; 0, N, cPr, H, Br, CF3], [AA604; 0, N, cPr, H, I, CF3], [AA605; 0, N, cPr, H, CF3, CF3], [AA606; 0, N, cPr, H, CF2H, CF3], [AA607; 0, N, cPr, H, C2F5, CF3], [AA608; 0, N, cPr, H, C3F7, CF3], [AA609; 0, N, cPr, H, CH2CF3, CF3], [AA610; 0, N, cPr, H, CH2CHF2, CF3], [AA611; 1, N, cPr, H, F, CF3], [AA612; 1, N, cPr, H, Cl, CF3], [AA613;[1,N,cPr,H,Br,CF3], [AA614; 1,N,cPr,H,I,CF3], [AA615; 1,N,cPr,H,CF3,CF3], [AA616; 1,N,cPr,H,CF2H,CF3], [AA617; 1,N,cPr,H,C2F5,CF3], [AA618; 1,N,cPr,H,C3F7,CF3], [AA619; 1,N,cPr,H,CH2CF3,CF3], [AA620; 1,N,cPr,H,CH2CHF2,CF3], [AA621; 2,N,cPr,H,F,CF3], [AA622; 2,N,cPr,H,Cl,CF3], [AA623; 2,N,cPr,H,Br,CF3], [AA624; 2,N,cPr,H,I,CF3], [AA625; 2,N,cPr,H,CF3,CF3], [AA626; 2,N,cPr,H,CF2H,CF3], [AA627; 2,N,cPr,H,C2F5,CF3], [AA628; 2,N,cPr,H,C3F7,CF3], [AA629; 2,N,cPr,H,CH2CF3,CF3], [AA630; 2,N,cPr,H,CH2CHF2,CF3], [AA631; 0,CH,H,H,H,CHF2], [AA632; 0,CH,H,F,H,CHF2], [AA633; 0,CH,H,Cl,H,CHF2], [AA634; 0,CH,H,Br,H,CHF2], [AA635; 0,CH,H,I,H,CHF2], [AA636; 0,CH,H,CF3,H,CHF2], [AA637; 0,CH,H,CF2H,H,CHF2], [AA638; 0,CH,H,C2F5,H,CHF2], [AA639; 0,CH,H,C3F7,H,CHF2], [AA640; 0,CH,H,CH2CF3,H,CHF2], [AA641; 0,CH,H,CH2CHF2,H,CHF2], [AA642; 1,CH,H,H,H,CHF2], [AA643; 1,CH,H,F,H,CHF2], [AA644; 1,CH,H,Cl,H,CHF2], [AA645; 1,CH,H,Br,H,CHF2], [AA646; 1,CH,H,I,H,CHF2], [AA647; 1,CH,H,CF3,H,CHF2], [AA648; 1,CH,H,CF2H,H,CHF2], [AA649; 1,CH,H,C2F5,H,CHF2], [AA650; 1,CH,H,C3F7,H,CHF2], [AA651;[1, CH, H, CH2CF3, H, CHF2], [AA652; 1, CH, H, CH2CHF2, H, CHF2], [AA653; 2, CH, H, H, H, CHF2], [AA654; 2, CH, H, F, H, CHF2], [AA655; 2, CH, H, Cl, H, CHF2], [AA656; 2, CH, H, Br, H, CHF2], [AA657; 2, CH, H, I, H, CHF2], [AA658; 2, CH, H, CF3, H, CHF2], [AA659; 2, CH, H, CF2H, H, CHF2], [AA660; 2, CH, H, C2F5, H, CHF2], [AA661; 2, CH, H, C3F7, H, CHF2], [AA662; 2, CH, H, CH2CF3, H, CHF2], [AA663; 2, CH, H, CH2CHF2, H, CHF2], [AA664; 0, N, H, H, H, CHF2], [AA665; 0, N, H, F, H, CHF2], [AA666; 0, N, H, Cl, H, CHF2], [AA667; 0, N, H, Br, H, CHF2], [AA668; 0, N, H, I, H, CHF2], [AA669; 0, N, H, CF3, H, CHF2], [AA670; 0, N, H, CF2H, H, CHF2], [AA671; 0, N, H, C2F5, H, CHF2], [AA672; 0, N, H, C3F7, H, CHF2], [AA673; 0, N, H, CH2CF3, H, CHF2], [AA674; 0, N, H, CH2CHF2, H, CHF2], [AA675; 1, N, H, H, H, CHF2], [AA676; 1, N, H, F, H, CHF2], [AA677; 1, N, H, Cl, H, CHF2], [AA678; 1, N, H, Br, H, CHF2], [AA679; 1, N, H, I, H, CHF2], [AA680; 1, N, H, CF3, H, CHF2], [AA681; 1, N, H, CF2H, H, CHF2], [AA682; 1, N, H, C2F5, H, CHF2], [AA683; 1, N, H, C3F7, H, CHF2], [AA684; 1, N, H, CH2CF3, H, CHF2], [AA685; 1, N, H, CH2CHF2, H, CHF2], [AA686; 2, N, H, H, H, CHF2], [AA687; 2, N, H, F, H, CHF2], [AA688; 2, N, H, Cl, H, CHF2], [AA689; 2, N, H, Br, H, CHF2], [AA690;[2,N,H,I,H,CHF2], [AA691; 2,N,H,CF3,H,CHF2], [AA692; 2,N,H,CF2H,H,CHF2], [AA693; 2,N,H,C2F5,H,CHF2], [AA694; 2,N,H,C3F7,H,CHF2], [AA695; 2,N,H,CH2CF3,H,CHF2], [AA696; 2,N,H,CH2CHF2,H,CHF2], [AA697; 0,CH,Me,H,H,CHF2], [AA698; 0,CH,Me,F,H,CHF2], [AA699; 0,CH,Me,Cl,H,CHF2], [AA700; 0,CH,Me,Br,H,CHF2], [AA701; 0,CH,Me,I,H,CHF2], [AA702; 0,CH,Me,CF3,H,CHF2], [AA703; 0,CH,Me,CF2H,H,CHF2], [AA704; 0,CH,Me,C2F5,H,CHF2], [AA705; 0,CH,Me,C3F7,H,CHF2], [AA706; 0,CH,Me,CH2CF3,H,CHF2], [AA707; 0,CH,Me,CH2CHF2,H,CHF2], [AA708; 1,CH,Me,H,H,CHF2], [AA709; 1,CH,Me,F,H,CHF2], [AA710; 1,CH,Me,Cl,H,CHF2], [AA711; 1,CH,Me,Br,H,CHF2], [AA712; 1,CH,Me,I,H,CHF2], [AA713; 1,CH,Me,CF3,H,CHF2], [AA714; 1,CH,Me,CF2H,H,CHF2], [AA715; 1,CH,Me,C2F5,H,CHF2], [AA716; 1,CH,Me,C3F7,H,CHF2], [AA717; 1,CH,Me,CH2CF3,H,CHF2], [AA718; 1,CH,Me,CH2CHF2,H,CHF2], [AA719; 2,CH,Me,H,H,CHF2], [AA720; 2,CH,Me,F,H,CHF2], [AA721; 2,CH,Me,Cl,H,CHF2], [AA722; 2,CH,Me,Br,H,CHF2], [AA723; 2,CH,Me,I,H,CHF2], [AA724; 2,CH,Me,CF3,H,CHF2], [AA725; 2,CH,Me,CF2H,H,CHF2], [AA726; 2,CH,Me,C2F5,H,CHF2], [AA727;[2,CH,Me,C3F7,H,CHF2], [AA728; 2,CH,Me,CH2CF3,H,CHF2], [AA729; 2,CH,Me,CH2CHF2,H,CHF2], [AA730; 0,N,Me,H,H,CHF2], [AA731; 0,N,Me,F,H,CHF2], [AA732; 0,N,Me,Cl,H,CHF2], [AA733; 0,N,Me,Br,H,CHF2], [AA734; 0,N,Me,I,H,CHF2], [AA735; 0,N,Me,CF3,H,CHF2], [AA736; 0,N,Me,CF2H,H,CHF2], [AA737; 0,N,Me,C2F5,H,CHF2], [AA738; 0,N,Me,C3F7,H,CHF2], [AA739; 0,N,Me,CH2CF3,H,CHF2], [AA740; 0,N,Me,CH2CHF2,H,CHF2], [AA741; 1,N,Me,H,H,CHF2], [AA742; 1,N,Me,F,H,CHF2], [AA743; 1,N,Me,Cl,H,CHF2], [AA744; 1,N,Me,Br,H,CHF2], [AA745; 1,N,Me,I,H,CHF2], [AA746; 1,N,Me,CF3,H,CHF2], [AA747; 1,N,Me,CF2H,H,CHF2], [AA748; 1,N,Me,C2F5,H,CHF2], [AA749; 1,N,Me,C3F7,H,CHF2], [AA750; 1,N,Me,CH2CF3,H,CHF2], [AA751; 1,N,Me,CH2CHF2,H,CHF2], [AA752; 2,N,Me,H,H,CHF2], [AA753; 2,N,Me,F,H,CHF2], [AA754; 2,N,Me,Cl,H,CHF2], [AA755; 2,N,Me,Br,H,CHF2], [AA756; 2,N,Me,I,H,CHF2], [AA757; 2,N,Me,CF3,H,CHF2], [AA758; 2,N,Me,CF2H,H,CHF2], [AA759; 2,N,Me,C2F5,H,CHF2], [AA760; 2,N,Me,C3F7,H,CHF2], [AA761; 2,N,Me,CH2CF3,H,CHF2], [AA762; 2,N,Me,CH2CHF2,H,CHF2], [AA763; 0,CH,Et,H,H,CHF2], [AA764;[0, CH, Et, F, H, CHF2], [AA765; 0, CH, Et, Cl, H, CHF2], [AA766; 0, CH, Et, Br, H, CHF2], [AA767; 0, CH, Et, I, H, CHF2], [AA768; 0, CH, Et, CF3, H, CHF2], [AA769; 0, CH, Et, CF2H, H, CHF2], [AA770; 0, CH, Et, C2F5, H, CHF2], [AA771; 0, CH, Et, C3F7, H, CHF2], [AA772; 0, CH, Et, CH2CF3, H, CHF2], [AA773; 0, CH, Et, CH2CHF2, H, CHF2], [AA774; 1, CH, Et, H, H, CHF2], [AA775; 1, CH, Et, F, H, CHF2], [AA776; 1, CH, Et, Cl, H, CHF2], [AA777; 1, CH, Et, Br, H, CHF2], [AA778; 1, CH, Et, I, H, CHF2], [AA779; 1, CH, Et, CF3, H, CHF2], [AA780; 1, CH, Et, CF2H, H, CHF2], [AA781; 1, CH, Et, C2F5, H, CHF2], [AA782; 1, CH, Et, C3F7, H, CHF2], [AA783; 1, CH, Et, CH2CF3, H, CHF2], [AA784; 1, CH, Et, CH2CHF2, H, CHF2], [AA785; 2, CH, Et, H, H, CHF2], [AA786; 2, CH, Et, F, H, CHF2], [AA787; 2, CH, Et, Cl, H, CHF2], [AA788; 2, CH, Et, Br, H, CHF2], [AA789; 2, CH, Et, I, H, CHF2], [AA790; 2, CH, Et, CF3, H, CHF2], [AA791; 2, CH, Et, CF2H, H, CHF2], [AA792; 2, CH, Et, C2F5, H, CHF2], [AA793; 2, CH, Et, C3F7, H, CHF2], [AA794; 2, CH, Et, CH2CF3, H, CHF2], [AA795; 2, CH, Et, CH2CHF2, H, CHF2], [AA796; 0, N, Et, H, H, CHF2], [AA797; 0, N, Et, F, H, CHF2], [AA798; 0, N, Et, Cl, H, CHF2], [AA799; 0, N, Et, Br, H, CHF2], [AA800; 0, N, Et, I, H, CHF2], [AA801;[0, N, Et, CF3, H, CHF2], [AA802; 0, N, Et, CF2H, H, CHF2], [AA803; 0, N, Et, C2F5, H, CHF2], [AA804; 0, N, Et, C3F7, H, CHF2], [AA805; 0, N, Et, CH2CF3, H, CHF2], [AA806; 0, N, Et, CH2CHF2, H, CHF2], [AA807; 1, N, Et, H, H, CHF2], [AA808; 1, N, Et, F, H, CHF2], [AA809; 1, N, Et, Cl, H, CHF2], [AA810; 1, N, Et, Br, H, CHF2], [AA811; 1, N, Et, I, H, CHF2], [AA812; 1, N, Et, CF3, H, CHF2], [AA813; 1, N, Et, CF2H, H, CHF2], [AA814; 1, N, Et, C2F5, H, CHF2], [AA815; 1, N, Et, C3F7, H, CHF2], [AA816; 1, N, Et, CH2CF3, H, CHF2], [AA817; 1, N, Et, CH2CHF2, H, CHF2], [AA818; 2, N, Et, H, H, CHF2], [AA819; 2, N, Et, F, H, CHF2], [AA820; 2, N, Et, Cl, H, CHF2], [AA821; 2, N, Et, Br, H, CHF2], [AA822; 2, N, Et, I, H, CHF2], [AA823; 2, N, Et, CF3, H, CHF2], [AA824; 2, N, Et, CF2H, H, CHF2], [AA825; 2, N, Et, C2F5, H, CHF2], [AA826; 2, N, Et, C3F7, H, CHF2], [AA827; 2, N, Et, CH2CF3, H, CHF2], [AA828; 2, N, Et, CH2CHF2, H, CHF2], [AA829; 0, CH, iPr, H, H, CHF2], [AA830; 0, CH, iPr, F, H, CHF2], [AA831; 0, CH, iPr, Cl, H, CHF2], [AA832; 0, CH, iPr, Br, H, CHF2], [AA833; 0, CH, iPr, I, H, CHF2], [AA834; 0, CH, iPr, CF3, H, CHF2], [AA835; 0, CH, iPr, CF2H, H, CHF2], [AA836; 0, CH, iPr, C2F5, H, CHF2], [AA837; 0, CH, iPr, C3F7, H, CHF2], [AA838;[0, CH, iPr, CH2CF3, H, CHF2], [AA839; 0, CH, iPr, CH2CHF2, H, CHF2], [AA840; 1, CH, iPr, H, H, CHF2], [AA841; 1, CH, iPr, F, H, CHF2], [AA842; 1, CH, iPr, Cl, H, CHF2], [AA843; 1, CH, iPr, Br, H, CHF2], [AA844; 1, CH, iPr, I, H, CHF2], [AA845; 1, CH, iPr, CF3, H, CHF2], [AA846; 1, CH, iPr, CF2H, H, CHF2], [AA847; 1, CH, iPr, C2F5, H, CHF2], [AA848; 1, CH, iPr, C3F7, H, CHF2], [AA849; 1, CH, iPr, CH2CF3, H, CHF2], [AA850; 1, CH, iPr, CH2CHF2, H, CHF2], [AA851; 2, CH, iPr, H, H, CHF2], [AA852; 2, CH, iPr, F, H, CHF2], [AA853; 2, CH, iPr, Cl, H, CHF2], [AA854; 2, CH, iPr, Br, H, CHF2], [AA855; 2, CH, iPr, I, H, CHF2], [AA856; 2, CH, iPr, CF3, H, CHF2], [AA857; 2, CH, iPr, CF2H, H, CHF2], [AA858; 2, CH, iPr, C2F5, H, CHF2], [AA859; 2, CH, iPr, C3F7, H, CHF2], [AA860; 2, CH, iPr, CH2CF3, H, CHF2], [AA861; 2, CH, iPr, CH2CHF2, H, CHF2], [AA862; 0, N, iPr, H, H, CHF2], [AA863; 0, N, iPr, F, H, CHF2], [AA864; 0, N, iPr, Cl, H, CHF2], [AA865; 0, N, iPr, Br, H, CHF2], [AA866; 0, N, iPr, I, H, CHF2], [AA867; 0, N, iPr, CF3, H, CHF2], [AA868; 0, N, iPr, CF2H, H, CHF2], [AA869; 0, N, iPr, C2F5, H, CHF2], [AA870; 0, N, iPr, C3F7, H, CHF2], [AA871; 0, N, iPr, CH2CF3, H, CHF2], [AA872; 0, N, iPr, CH2CHF2, H, CHF2], [AA873;1,N,iPr,H,H,CHF2], [AA874; 1,N,iPr,F,H,CHF2], [AA875; 1,N,iPr,Cl,H,CHF2], [AA876; 1,N,iPr,Br,H,CHF2], [AA877; 1,N,iPr,I,H,CHF2], [AA878; 1,N,iPr,CF3,H,CHF2], [AA879; 1,N,iPr,CF2H,H,CHF2], [AA880; 1,N,iPr,C2F5,H,CHF2], [AA881; 1,N,iPr,C3F7,H,CHF2], [AA882; 1,N,iPr,CH2CF3,H,CHF2], [AA883; 1,N,iPr,CH2CHF2,H,CHF2], [AA884; 2,N,iPr,H,H,CHF2], [AA885; 2,N,iPr,F,H,CHF2], [AA886; 2,N,iPr,Cl,H,CHF2], [AA887; 2,N,iPr,Br,H,CHF2], [AA888; 2,N,iPr,I,H,CHF2], [AA889; 2,N,iPr,CF3,H,CHF2], [AA890; 2,N,iPr,CF2H,H,CHF2], [AA891; 2,N,iPr,C2F5,H,CHF2], [AA892; 2,N,iPr,C3F7,H,CHF2], [AA893; 2,N,iPr,CH2CF3,H,CHF2], [AA894; 2,N,iPr,CH2CHF2,H,CHF2], [AA895; 0,CH,cPr,H,H,CHF2], [AA896; 0,CH,cPr,F,H,CHF2], [AA897; 0,CH,cPr,Cl,H,CHF2], [AA898; 0,CH,cPr,Br,H,CHF2], [AA899; 0,CH,cPr,I,H,CHF2], [AA900; 0,CH,cPr,CF3,H,CHF2], [AA901; 0,CH,cPr,CF2H,H,CHF2], [AA902; 0,CH,cPr,C2F5,H,CHF2], [AA903; 0,CH,cPr,C3F7,H,CHF2], [AA904; 0,CH,cPr,CH2CF3,H,CHF2], [AA905; 0,CH,cPr,CH2CHF2,H,CHF2], [AA906; 1,CH,cPr,H,H,CHF2], [AA907; 1,CH,cPr,F,H,CHF2], [AA908; 1,CH,cPr,Cl,H,CHF2], [AA909;[1, CH, cPr, Br, H, CHF2], [AA910; 1, CH, cPr, I, H, CHF2], [AA911; 1, CH, cPr, CF3, H, CHF2], [AA912; 1, CH, cPr, CF2H, H, CHF2], [AA913; 1, CH, cPr, C2F5, H, CHF2], [AA914; 1, CH, cPr, C3F7, H, CHF2], [AA915; 1, CH, cPr, CH2CF3, H, CHF2], [AA916; 1, CH, cPr, CH2CHF2, H, CHF2], [AA917; 2, CH, cPr, H, H, CHF2], [AA918; 2, CH, cPr, F, H, CHF2], [AA919; 2, CH, cPr, Cl, H, CHF2], [AA920; 2, CH, cPr, Br, H, CHF2], [AA921; 2, CH, cPr, I, H, CHF2], [AA922; 2, CH, cPr, CF3, H, CHF2], [AA923; 2, CH, cPr, CF2H, H, CHF2], [AA924; 2, CH, cPr, C2F5, H, CHF2], [AA925; 2, CH, cPr, C3F7, H, CHF2], [AA926; 2, CH, cPr, CH2CF3, H, CHF2], [AA927; 2, CH, cPr, CH2CHF2, H, CHF2], [AA928; 0, N, cPr, H, H, CHF2], [AA929; 0, N, cPr, F, H, CHF2], [AA930; 0, N, cPr, Cl, H, CHF2], [AA931; 0, N, cPr, Br, H, CHF2], [AA932; 0, N, cPr, I, H, CHF2], [AA933; 0, N, cPr, CF3, H, CHF2], [AA934; 0, N, cPr, CF2H, H, CHF2], [AA935; 0, N, cPr, C2F5, H, CHF2], [AA936; 0, N, cPr, C3F7, H, CHF2], [AA937; 0, N, cPr, CH2CF3, H, CHF2], [AA938; 0, N, cPr, CH2CHF2, H, CHF2], [AA939; 1, N, cPr, H, H, CHF2], [AA940; 1, N, cPr, F, H, CHF2], [AA941; 1, N, cPr, Cl, H, CHF2], [AA942; 1, N, cPr, Br, H, CHF2], [AA943; 1, N, cPr, I, H, CHF2], [AA944; 1, N, cPr, CF3, H, CHF2], [AA945;[1, N, cPr, CF2H, H, CHF2], [AA946; 1, N, cPr, C2F5, H, CHF2], [AA947; 1, N, cPr, C3F7, H, CHF2], [AA948; 1, N, cPr, CH2CF3, H, CHF2], [AA949; 1, N, cPr, CH2CHF2, H, CHF2], [AA950; 2, N, cPr, H, H, CHF2], [AA951; 2, N, cPr, F, H, CHF2], [AA952; 2, N, cPr, Cl, H, CHF2], [AA953; 2, N, cPr, Br, H, CHF2], [AA954; 2, N, cPr, I, H, CHF2], [AA955; 2, N, cPr, CF3, H, CHF2], [AA956; 2, N, cPr, CF2H, H, CHF2], [AA957; 2, N, cPr, C2F5, H, CHF2], [AA958; 2, N, cPr, C3F7, H, CHF2], [AA959; 2, N, cPr, CH2CF3, H, CHF2], [AA960; 2, N, cPr, CH2CHF2, H, CHF2], [AA961; 0, CH, H, H, F, CHF2], [AA962; 0, CH, H, H, Cl, CHF2], [AA963; 0, CH, H, H, Br, CHF2], [AA964; 0, CH, H, H, I, CHF2], [AA965; 0, CH, H, H, CF3, CHF2], [AA966; 0, CH, H, H, CF2H, CHF2], [AA967; 0, CH, H, H, C2F5, CHF2], [AA968; 0, CH, H, H, C3F7, CHF2], [AA969; 0, CH, H, H, CH2CF3, CHF2], [AA970; 0, CH, H, H, CH2CHF2, CHF2], [AA971; 1, CH, H, H, F, CHF2], [AA972; 1, CH, H, H, Cl, CHF2], [AA973; 1, CH, H, H, Br, CHF2], [AA974; 1, CH, H, H, I, CHF2], [AA975; 1, CH, H, H, CF3, CHF2], [AA976; 1, CH, H, H, CF2H, CHF2], [AA977; 1, CH, H, H, C2F5, CHF2], [AA978; 1, CH, H, H, C3F7, CHF2], [AA979; 1, CH, H, H, CH2CF3, CHF2], [AA980; 1, CH, H, H, CH2CHF2, CHF2], [AA981; 2, CH, H, H, F, CHF2], [AA982;[2, CH, H, H, Cl, CHF2], [AA983; 2, CH, H, H, Br, CHF2], [AA984; 2, CH, H, H, I, CHF2], [AA985; 2, CH, H, H, CF3, CHF2], [AA986; 2, CH, H, H, CF2H, CHF2], [AA987; 2, CH, H, H, C2F5, CHF2], [AA988; 2, CH, H, H, C3F7, CHF2], [AA989; 2, CH, H, H, CH2CF3, CHF2], [AA990; 2, CH, H, H, CH2CHF2, CHF2], [AA991; 0, N, H, H, F, CHF2], [AA992; 0, N, H, H, Cl, CHF2], [AA993; 0, N, H, H, Br, CHF2], [AA994; 0, N, H, H, I, CHF2], [AA995; 0, N, H, H, CF3, CHF2], [AA996; 0, N, H, H, CF2H, CHF2], [AA997; 0, N, H, H, C2F5, CHF2], [AA998; 0, N, H, H, C3F7, CHF2], [AA999; 0, N, H, H, CH2CF3, CHF2], [AA1000; 0, N, H, H, CH2CHF2, CHF2], [AA1001; 1, N, H, H, F, CHF2], [AA1002; 1, N, H, H, Cl, CHF2], [AA1003; 1, N, H, H, Br, CHF2], [AA1004; 1, N, H, H, I, CHF2], [AA1005; 1, N, H, H, CF3, CHF2], [AA1006; 1, N, H, H, CF2H, CHF2], [AA1007; 1, N, H, H, C2F5, CHF2], [AA1008; 1, N, H, H, C3F7, CHF2], [AA1009; 1, N, H, H, CH2CF3, CHF2], [AA1010; 1, N, H, H, CH2CHF2, CHF2], [AA1011; 2, N, H, H, F, CHF2], [AA1012; 2, N, H, H, Cl, CHF2], [AA1013; 2, N, H, H, Br, CHF2], [AA1014; 2, N, H, H, I, CHF2], [AA1015; 2, N, H, H, CF3, CHF2], [AA1016; 2, N, H, H, CF2H, CHF2], [AA1017; 2, N, H, H, C2F5, CHF2], [AA1018; 2, N, H, H, C3F7, CHF2], [AA1019; 2, N, H, H, CH2CF3, CHF2], [AA1020;[2, N, H, H, CH2CHF2, CHF2], [AA1021; 0, CH, Me, H, F, CHF2], [AA1022; 0, CH, Me, H, Cl, CHF2], [AA1023; 0, CH, Me, H, Br, CHF2], [AA1024; 0, CH, Me, H, I, CHF2], [AA1025; 0, CH, Me, H, CF3, CHF2], [AA1026; 0, CH, Me, H, CF2H, CHF2], [AA1027; 0, CH, Me, H, C2F5, CHF2], [AA1028; 0, CH, Me, H, C3F7, CHF2], [AA1029; 0, CH, Me, H, CH2CF3, CHF2], [AA1030; 0, CH, Me, H, CH2CHF2, CHF2], [AA1031; 1, CH, Me, H, F, CHF2], [AA1032; 1, CH, Me, H, Cl, CHF2], [AA1033; 1, CH, Me, H, Br, CHF2], [AA1034; 1, CH, Me, H, I, CHF2], [AA1035; 1, CH, Me, H, CF3, CHF2], [AA1036; 1, CH, Me, H, CF2H, CHF2], [AA1037; 1, CH, Me, H, C2F5, CHF2], [AA1038; 1, CH, Me, H, C3F7, CHF2], [AA1039; 1, CH, Me, H, CH2CF3, CHF2], [AA1040; 1, CH, Me, H, CH2CHF2, CHF2], [AA1041; 2, CH, Me, H, F, CHF2], [AA1042; 2, CH, Me, H, Cl, CHF2], [AA1043; 2, CH, Me, H, Br, CHF2], [AA1044; 2, CH, Me, H, I, CHF2], [AA1045; 2, CH, Me, H, CF3, CHF2], [AA1046; 2, CH, Me, H, CF2H, CHF2], [AA1047; 2, CH, Me, H, C2F5, CHF2], [AA1048; 2, CH, Me, H, C3F7, CHF2], [AA1049; 2, CH, Me, H, CH2CF3, CHF2], [AA1050; 2, CH, Me, H, CH2CHF2, CHF2], [AA1051; 0, N, Me, H, F, CHF2], [AA1052; 0, N, Me, H, Cl, CHF2], [AA1053; 0, N, Me, H, Br, CHF2], [AA1054; 0, N, Me, H, I, CHF2], [AA1055;[[0,N,Me,H,CF3,CHF2]], [[AA1056; 0,N,Me,H,CF2H,CHF2]], [[AA1057; 0,N,Me,H,C2F5,CHF2]], [[AA1058; 0,N,Me,H,C3F7,CHF2]], [[AA1059; 0,N,Me,H,CH2CF3,CHF2]], [[AA1060; 0,N,Me,H,CH2CHF2,CHF2]], [[AA1061; 1,N,Me,H,F,CHF2]], [[AA1062; 1,N,Me,H,Cl,CHF2]], [[AA1063; 1,N,Me,H,Br,CHF2]], [[AA1064; 1,N,Me,H,I,CHF2]], [[AA1065; 1,N,Me,H,CF3,CHF2]], [[AA1066; 1,N,Me,H,CF2H,CHF2]], [[AA1067; 1,N,Me,H,C2F5,CHF2]], [[AA1068; 1,N,Me,H,C3F7,CHF2]], [[AA1069; 1,N,Me,H,CH2CF3,CHF2]], [[AA1070; 1,N,Me,H,CH2CHF2,CHF2]], [[AA1071; 2,N,Me,H,F,CHF2]], [[AA1072; 2,N,Me,H,Cl,CHF2]], [[AA1073; 2,N,Me,H,Br,CHF2]], [[AA1074; 2,N,Me,H,I,CHF2]], [[AA1075; 2,N,Me,H,CF3,CHF2]], [[AA1076; 2,N,Me,H,CF2H,CHF2]], [[AA1077; 2,N,Me,H,C2F5,CHF2]], [[AA1078; 2,N,Me,H,C3F7,CHF2]], [[AA1079; 2,N,Me,H,CH2CF3,CHF2]], [[AA1080; 2,N,Me,H,CH2CHF2,CHF2]], [[AA1081; 0,CH,Et,H,F,CHF2]], [[AA1082; 0,CH,Et,H,Cl,CHF2]], [[AA1083; 0,CH,Et,H,Br,CHF2]], [[AA1084; 0,CH,Et,H,I,CHF2]], [[AA1085; 0,CH,Et,H,CF3,CHF2]], [[AA1086; 0,CH,Et,H,CF2H,CHF2]], [[AA1087; 0,CH,Et,H,C2F5,CHF2]], [[AA1088; 0,CH,Et,H,C3F7,CHF2]], [[AA1089; 0,CH,Et,H,CH2CF3,CHF2]], [[AA1090;[[0, CH, Et, H, CH2CHF2, CHF2]], [[AA1091; 1, CH, Et, H, F, CHF2]], [[AA1092; 1, CH, Et, H, Cl, CHF2]], [[AA1093; 1, CH, Et, H, Br, CHF2]], [[AA1094; 1, CH, Et, H, I, CHF2]], [[AA1095; 1, CH, Et, H, CF3, CHF2]], [[AA1096; 1, CH, Et, H, CF2H, CHF2]], [[AA1097; 1, CH, Et, H, C2F5, CHF2]], [[AA1098; 1, CH, Et, H, C3F7, CHF2]], [[AA1099; 1, CH, Et, H, CH2CF3, CHF2]], [[AA1100; 1, CH, Et, H, CH2CHF2, CHF2]];
[0603] [AA1101; 2, CH, Et, H, F, CHF2], [AA1102; 2, CH, Et, H, Cl, CHF2], [AA1103; 2, CH, Et, H, Br, CHF2], [AA1104; 2, CH, Et, H, I, CHF2], [AA1105; 2, CH, Et, H, CF3, CHF2], [AA1106; 2, CH, Et, H, CF2H, CHF2], [AA1107; 2, CH, Et, H, C2F5, CHF2], [AA1108; 2, CH, Et, H, C3F7, CHF2], [AA1109; 2, CH, Et, H, CH2CF3, CHF2], [AA1110; 2, CH, Et, H, CH2CHF2, CHF2], [AA1111; 0, N, Et, H, F, CHF2], [AA1112; 0, N, Et, H, Cl, CHF2], [AA1113; 0, N, Et, H, Br, CHF2], [AA1114; 0, N, Et, H, I, CHF2], [AA1115; 0, N, Et, H, CF3, CHF2], [AA1116; 0, N, Et, H, CF2H, CHF2], [AA1117; 0, N, Et, H, C2F5, CHF2], [AA1118; 0, N, Et, H, C3F7, CHF2], [AA1119; 0, N, Et, H, CH2CF3, CHF2], [AA1120; 0, N, Et, H, CH2CHF2, CHF2], [AA1121; 1, N, Et, H, F, CHF2], [AA1122; 1, N, Et, H, Cl, CHF2], [AA1123; 1, N, Et, H, Br, CHF2], [AA1124; 1, N, Et, H, I, CHF2], [AA1125; 1, N, Et, H, CF3, CHF2], [AA1126; 1, N, Et, H, CF2H, CHF2], [AA1127; 1, N, Et, H, C2F5, CHF2], [AA1128; 1, N, Et, H, C3F7, CHF2], [AA1129; 1, N, Et, H, CH2CF3, CHF2], [AA1130; 1, N, Et, H, CH2CHF2, CHF2], [AA1131; 2, N, Et, H, F, CHF2], [AA1132; 2, N, Et, H, Cl, CHF2], [AA1133; 2, N, Et, H, Br, CHF2], [AA1134; 2, N, Et, H, I, CHF2], [AA1135; 2, N, Et, H, CF3, CHF2], [AA1136; 2, N, Et, H, CF2H, CHF2], [AA1137;[2,N,Et,H,C2F5,CHF2], [AA1138; 2,N,Et,H,C3F7,CHF2], [AA1139; 2,N,Et,H,CH2CF3,CHF2], [AA1140; 2,N,Et,H,CH2CHF2,CHF2], [AA1141; 0,CH,iPr,H,F,CHF2], [AA1142; 0,CH,iPr,H,Cl,CHF2], [AA1143; 0,CH,iPr,H,Br,CHF2], [AA1144; 0,CH,iPr,H,I,CHF2], [AA1145; 0,CH,iPr,H,CF3,CHF2], [AA1146; 0,CH,iPr,H,CF2H,CHF2], [AA1147; 0,CH,iPr,H,C2F5,CHF2], [AA1148; 0,CH,iPr,H,C3F7,CHF2], [AA1149; 0,CH,iPr,H,CH2CF3,CHF2], [AA1150; 0,CH,iPr,H,CH2CHF2,CHF2], [AA1151; 1,CH,iPr,H,F,CHF2], [AA1152; 1,CH,iPr,H,Cl,CHF2], [AA1153; 1,CH,iPr,H,Br,CHF2], [AA1154; 1,CH,iPr,H,I,CHF2], [AA1155; 1,CH,iPr,H,CF3,CHF2], [AA1156; 1,CH,iPr,H,CF2H,CHF2], [AA1157; 1,CH,iPr,H,C2F5,CHF2], [AA1158; 1,CH,iPr,H,C3F7,CHF2], [AA1159; 1,CH,iPr,H,CH2CF3,CHF2], [AA1160; 1,CH,iPr,H,CH2CHF2,CHF2], [AA1161; 2,CH,iPr,H,F,CHF2], [AA1162; 2,CH,iPr,H,Cl,CHF2], [AA1163; 2,CH,iPr,H,Br,CHF2], [AA1164; 2,CH,iPr,H,I,CHF2], [AA1165; 2,CH,iPr,H,CF3,CHF2], [AA1166; 2,CH,iPr,H,CF2H,CHF2], [AA1167; 2,CH,iPr,H,C2F5,CHF2], [AA1168; 2,CH,iPr,H,C3F7,CHF2], [AA1169; 2,CH,iPr,H,CH2CF3,CHF2], [AA1170; 2,CH,iPr,H,CH2CHF2,CHF2], [AA1171;[0,N,iPr,H,F,CHF2], [AA1172; 0,N,iPr,H,Cl,CHF2], [AA1173; 0,N,iPr,H,Br,CHF2], [AA1174; 0,N,iPr,H,I,CHF2], [AA1175; 0,N,iPr,H,CF3,CHF2], [AA1176; 0,N,iPr,H,CF2H,CHF2], [AA1177; 0,N,iPr,H,C2F5,CHF2], [AA1178; 0,N,iPr,H,C3F7,CHF2], [AA1179; 0,N,iPr,H,CH2CF3,CHF2], [AA1180; 0,N,iPr,H,CH2CHF2,CHF2], [AA1181; 1,N,iPr,H,F,CHF2], [AA1182; 1,N,iPr,H,Cl,CHF2], [AA1183; 1,N,iPr,H,Br,CHF2], [AA1184; 1,N,iPr,H,I,CHF2], [AA1185; 1,N,iPr,H,CF3,CHF2], [AA1186; 1,N,iPr,H,CF2H,CHF2], [AA1187; 1,N,iPr,H,C2F5,CHF2], [AA1188; 1,N,iPr,H,C3F7,CHF2], [AA1189; 1,N,iPr,H,CH2CF3,CHF2], [AA1190; 1,N,iPr,H,CH2CHF2,CHF2], [AA1191; 2,N,iPr,H,F,CHF2], [AA1192; 2,N,iPr,H,Cl,CHF2], [AA1193; 2,N,iPr,H,Br,CHF2], [AA1194; 2,N,iPr,H,I,CHF2], [AA1195; 2,N,iPr,H,CF3,CHF2], [AA1196; 2,N,iPr,H,CF2H,CHF2], [AA1197; 2,N,iPr,H,C2F5,CHF2], [AA1198; 2,N,iPr,H,C3F7,CHF2], [AA1199; 2,N,iPr,H,CH2CF3,CHF2], [AA1200; 2,N,iPr,H,CH2CHF2,CHF2];
[0604] [AA1201; 0, CH, cPr, H, F, CHF2], [AA1202; 0, CH, cPr, H, Cl, CHF2], [AA1203; 0, CH, cPr, H, Br, CHF2], [AA1204; 0, CH, cPr, H, I, CHF2], [AA1205; 0, CH, cPr, H, CF3, CHF2], [AA1206; 0, CH, cPr, H, CF2H, CHF2], [AA1207; 0, CH, cPr, H, C2F5, CHF2], [AA1208; 0, CH, cPr, H, C3F7, CHF2], [AA1209; 0, CH, cPr, H, CH2CF3, CHF2], [AA1210; 0, CH, cPr, H, CH2CHF2, CHF2], [AA1211; 1, CH, cPr, H, F, CHF2], [AA1212; 1, CH, cPr, H, Cl, CHF2], [AA1213; 1, CH, cPr, H, Br, CHF2], [AA1214; 1, CH, cPr, H, I, CHF2], [AA1215; 1, CH, cPr, H, CF3, CHF2], [AA1216; 1, CH, cPr, H, CF2H, CHF2], [AA1217; 1, CH, cPr, H, C2F5, CHF2], [AA1218; 1, CH, cPr, H, C3F7, CHF2], [AA1219; 1, CH, cPr, H, CH2CF3, CHF2], [AA1220; 1, CH, cPr, H, CH2CHF2, CHF2], [AA1221; 2, CH, cPr, H, F, CHF2], [AA1222; 2, CH, cPr, H, Cl, CHF2], [AA1223; 2, CH, cPr, H, Br, CHF2], [AA1224; 2, CH, cPr, H, I, CHF2], [AA1225; 2, CH, cPr, H, CF3, CHF2], [AA1226; 2, CH, cPr, H, CF2H, CHF2], [AA1227; 2, CH, cPr, H, C2F5, CHF2], [AA1228; 2, CH, cPr, H, C3F7, CHF2], [AA1229; 2, CH, cPr, H, CH2CF3, CHF2], [AA1230; 2, CH, cPr, H, CH2CHF2, CHF2], [AA1231; 0, N, cPr, H, F, CHF2], [AA1232; 0, N, cPr, H, Cl, CHF2], [AA1233; 0, N, cPr, H, Br, CHF2], [AA1234; 0, N, cPr, H, I, CHF2], [AA1235;[0, N, cPr, H, CF3, CHF2], [AA1236; 0, N, cPr, H, CF2H, CHF2], [AA1237; 0, N, cPr, H, C2F5, CHF2], [AA1238; 0, N, cPr, H, C3F7, CHF2], [AA1239; 0, N, cPr, H, CH2CF3, CHF2], [AA1240; 0, N, cPr, H, CH2CHF2, CHF2], [AA1241; 1, N, cPr, H, F, CHF2], [AA1242; 1, N, cPr, H, Cl, CHF2], [AA1243; 1, N, cPr, H, Br, CHF2], [AA1244; 1, N, cPr, H, I, CHF2], [AA1245; 1, N, cPr, H, CF3, CHF2], [AA1246; 1, N, cPr, H, CF2H, CHF2], [AA1247; 1, N, cPr, H, C2F5, CHF2], [AA1248; 1, N, cPr, H, C3F7, CHF2], [AA1249; 1, N, cPr, H, CH2CF3, CHF2], [AA1250; 1, N, cPr, H, CH2CHF2, CHF2], [AA1251; 2, N, cPr, H, F, CHF2], [AA1252; 2, N, cPr, H, Cl, CHF2], [AA1253; 2, N, cPr, H, Br, CHF2], [AA1254; 2, N, cPr, H, I, CHF2], [AA1255; 2, N, cPr, H, CF3, CHF2], [AA1256; 2, N, cPr, H, CF2H, CHF2], [AA1257; 2, N, cPr, H, C2F5, CHF2], [AA1258; 2, N, cPr, H, C3F7, CHF2], [AA1259; 2, N, cPr, H, CH2CF3, CHF2], [AA1260; 2, N, cPr, H, CH2CHF2, CHF2], [AA1261; 0, CH, H, H, H, CH2CF3], [AA1262; 0, CH, H, F, H, CH2CF3], [AA1263; 0, CH, H, Cl, H, CH2CF3], [AA1264; 0, CH, H, Br, H, CH2CF3], [AA1265; 0, CH, H, I, H, CH2CF3], [AA1266; 0, CH, H, CF3, H, CH2CF3], [AA1267; 0, CH, H, CF2H, H, CH2CF3], [AA1268; 0, CH, H, C2F5, H, CH2CF3], [AA1269;[0, CH, H, C3F7, H, CH2CF3], [AA1270; 0, CH, H, CH2CF3, H, CH2CF3], [AA1271; 0, CH, H, CH2CHF2, H, CH2CF3], [AA1272; 1, CH, H, H, H, CH2CF3], [AA1273; 1, CH, H, F, H, CH2CF3], [AA1274; 1, CH, H, Cl, H, CH2CF3], [AA1275; 1, CH, H, Br, H, CH2CF3], [AA1276; 1, CH, H, I, H, CH2CF3], [AA1277; 1, CH, H, CF3, H, CH2CF3], [AA1278; 1, CH, H, CF2H, H, CH2CF3], [AA1279; 1, CH, H, C2F5, H, CH2CF3], [AA1280; 1, CH, H, C3F7, H, CH2CF3], [AA1281; 1, CH, H, CH2CF3, H, CH2CF3], [AA1282; 1, CH, H, CH2CHF2, H, CH2CF3], [AA1283; 2, CH, H, H, H, CH2CF3], [AA1284; 2, CH, H, F, H, CH2CF3], [AA1285; 2, CH, H, Cl, H, CH2CF3], [AA1286; 2, CH, H, Br, H, CH2CF3], [AA1287; 2, CH, H, I, H, CH2CF3], [AA1288; 2, CH, H, CF3, H, CH2CF3], [AA1289; 2, CH, H, CF2H, H, CH2CF3], [AA1290; 2, CH, H, C2F5, H, CH2CF3], [AA1291; 2, CH, H, C3F7, H, CH2CF3], [AA1292; 2, CH, H, CH2CF3, H, CH2CF3], [AA1293; 2, CH, H, CH2CHF2, H, CH2CF3], [AA1294; 0, N, H, H, H, CH2CF3], [AA1295; 0, N, H, F, H, CH2CF3], [AA1296; 0, N, H, Cl, H, CH2CF3], [AA1297; 0, N, H, Br, H, CH2CF3], [AA1298; 0, N, H, I, H, CH2CF3], [AA1299; 0, N, H, CF3, H, CH2CF3], [AA1300; 0, N, H, CF2H, H, CH2CF3];
[0605] [AA1301; 0, N, H, C2F5, H, CH2CF3], [AA1302; 0, N, H, C3F7, H, CH2CF3], [AA1303; 0, N, H, CH2CF3, H, CH2CF3], [AA1304; 0, N, H, CH2CHF2, H, CH2CF3], [AA1305; 1, N, H, H, H, CH2CF3], [AA1306; 1, N, H, F, H, CH2CF3], [AA1307; 1, N, H, Cl, H, CH2CF3], [AA1308; 1, N, H, Br, H, CH2CF3], [AA1309; 1, N, H, I, H, CH2CF3], [AA1310; 1, N, H, CF3, H, CH2CF3], [AA1311; 1, N, H, CF2H, H, CH2CF3], [AA1312; 1, N, H, C2F5, H, CH2CF3], [AA1313; 1, N, H, C3F7, H, CH2CF3], [AA1314; 1, N, H, CH2CF3, H, CH2CF3], [AA1315; 1, N, H, CH2CHF2, H, CH2CF3], [AA1316; 2, N, H, H, H, CH2CF3], [AA1317; 2, N, H, F, H, CH2CF3], [AA1318; 2, N, H, Cl, H, CH2CF3], [AA1319; 2, N, H, Br, H, CH2CF3], [AA1320; 2, N, H, I, H, CH2CF3], [AA1321; 2, N, H, CF3, H, CH2CF3], [AA1322; 2, N, H, CF2H, H, CH2CF3], [AA1323; 2, N, H, C2F5, H, CH2CF3], [AA1324; 2, N, H, C3F7, H, CH2CF3], [AA1325; 2, N, H, CH2CF3, H, CH2CF3], [AA1326; 2, N, H, CH2CHF2, H, CH2CF3], [AA1327; 0, CH, Me, H, H, CH2CF3], [AA1328; 0, CH, Me, F, H, CH2CF3], [AA1329; 0, CH, Me, Cl, H, CH2CF3], [AA1330; 0, CH, Me, Br, H, CH2CF3], [AA1331; 0, CH, Me, I, H, CH2CF3], [AA1332; 0, CH, Me, CF3, H, CH2CF3], [AA1333; 0, CH, Me, CF2H, H, CH2CF3], [AA1334; 0, CH, Me, C2F5, H, CH2CF3], [AA1335;[0, CH, Me, C3F7, H, CH2CF3], [AA1336; 0, CH, Me, CH2CF3, H, CH2CF3], [AA1337; 0, CH, Me, CH2CHF2, H, CH2CF3], [AA1338; 1, CH, Me, H, H, CH2CF3], [AA1339; 1, CH, Me, F, H, CH2CF3], [AA1340; 1, CH, Me, Cl, H, CH2CF3], [AA1341; 1, CH, Me, Br, H, CH2CF3], [AA1342; 1, CH, Me, I, H, CH2CF3], [AA1343; 1, CH, Me, CF3, H, CH2CF3], [AA1344; 1, CH, Me, CF2H, H, CH2CF3], [AA1345; 1, CH, Me, C2F5, H, CH2CF3], [AA1346; 1, CH, Me, C3F7, H, CH2CF3], [AA1347; 1, CH, Me, CH2CF3, H, CH2CF3], [AA1348; 1, CH, Me, CH2CHF2, H, CH2CF3], [AA1349; 2, CH, Me, H, H, CH2CF3], [AA1350; 2, CH, Me, F, H, CH2CF3], [AA1351; 2, CH, Me, Cl, H, CH2CF3], [AA1352; 2, CH, Me, Br, H, CH2CF3], [AA1353; 2, CH, Me, I, H, CH2CF3], [AA1354; 2, CH, Me, CF3, H, CH2CF3], [AA1355; 2, CH, Me, CF2H, H, CH2CF3], [AA1356; 2, CH, Me, C2F5, H, CH2CF3], [AA1357; 2, CH, Me, C3F7, H, CH2CF3], [AA1358; 2, CH, Me, CH2CF3, H, CH2CF3], [AA1359; 2, CH, Me, CH2CHF2, H, CH2CF3], [AA1360; 0, N, Me, H, H, CH2CF3], [AA1361; 0, N, Me, F, H, CH2CF3], [AA1362; 0, N, Me, Cl, H, CH2CF3], [AA1363; 0, N, Me, Br, H, CH2CF3], [AA1364; 0, N, Me, I, H, CH2CF3], [AA1365; 0, N, Me, CF3, H, CH2CF3], [AA1366; 0, N, Me, CF2H, H, CH2CF3], [AA1367; 0, N, Me, C2F5, H, CH2CF3], [AA1368;[0, N, Me, C3F7, H, CH2CF3], [AA1369; 0, N, Me, CH2CF3, H, CH2CF3], [AA1370; 0, N, Me, CH2CHF2, H, CH2CF3], [AA1371; 1, N, Me, H, H, CH2CF3], [AA1372; 1, N, Me, F, H, CH2CF3], [AA1373; 1, N, Me, Cl, H, CH2CF3], [AA1374; 1, N, Me, Br, H, CH2CF3], [AA1375; 1, N, Me, I, H, CH2CF3], [AA1376; 1, N, Me, CF3, H, CH2CF3], [AA1377; 1, N, Me, CF2H, H, CH2CF3], [AA1378; 1, N, Me, C2F5, H, CH2CF3], [AA1379; 1, N, Me, C3F7, H, CH2CF3], [AA1380; 1, N, Me, CH2CF3, H, CH2CF3], [AA1381; 1, N, Me, CH2CHF2, H, CH2CF3], [AA1382; 2, N, Me, H, H, CH2CF3], [AA1383; 2, N, Me, F, H, CH2CF3], [AA1384; 2, N, Me, Cl, H, CH2CF3], [AA1385; 2, N, Me, Br, H, CH2CF3], [AA1386; 2, N, Me, I, H, CH2CF3], [AA1387; 2, N, Me, CF3, H, CH2CF3], [AA1388; 2, N, Me, CF2H, H, CH2CF3], [AA1389; 2, N, Me, C2F5, H, CH2CF3], [AA1390; 2, N, Me, C3F7, H, CH2CF3], [AA1391; 2, N, Me, CH2CF3, H, CH2CF3], [AA1392; 2, N, Me, CH2CHF2, H, CH2CF3], [AA1393; 0, CH, Et, H, H, CH2CF3], [AA1394; 0, CH, Et, F, H, CH2CF3], [AA1395; 0, CH, Et, Cl, H, CH2CF3], [AA1396; 0, CH, Et, Br, H, CH2CF3], [AA1397; 0, CH, Et, I, H, CH2CF3], [AA1398; 0, CH, Et, CF3, H, CH2CF3], [AA1399; 0, CH, Et, CF2H, H, CH2CF3], [AA1400; 0, CH, Et, C2F5, H, CH2CF3], [AA1401;[0, CH, Et, C3F7, H, CH2CF3], [AA1402; 0, CH, Et, CH2CF3, H, CH2CF3], [AA1403; 0, CH, Et, CH2CHF2, H, CH2CF3], [AA1404; 1, CH, Et, H, H, CH2CF3], [AA1405; 1, CH, Et, F, H, CH2CF3], [AA1406; 1, CH, Et, Cl, H, CH2CF3], [AA1407; 1, CH, Et, Br, H, CH2CF3], [AA1408; 1, CH, Et, I, H, CH2CF3], [AA1409; 1, CH, Et, CF3, H, CH2CF3], [AA1410; 1, CH, Et, CF2H, H, CH2CF3], [AA1411; 1, CH, Et, C2F5, H, CH2CF3], [AA1412; 1, CH, Et, C3F7, H, CH2CF3], [AA1413; 1, CH, Et, CH2CF3, H, CH2CF3], [AA1414; 1, CH, Et, CH2CHF2, H, CH2CF3], [AA1415; 2, CH, Et, H, H, CH2CF3], [AA1416; 2, CH, Et, F, H, CH2CF3], [AA1417; 2, CH, Et, Cl, H, CH2CF3], [AA1418; 2, CH, Et, Br, H, CH2CF3], [AA1419; 2, CH, Et, I, H, CH2CF3], [AA1420; 2, CH, Et, CF3, H, CH2CF3], [AA1421; 2, CH, Et, CF2H, H, CH2CF3], [AA1422; 2, CH, Et, C2F5, H, CH2CF3], [AA1423; 2, CH, Et, C3F7, H, CH2CF3], [AA1424; 2, CH, Et, CH2CF3, H, CH2CF3], [AA1425; 2, CH, Et, CH2CHF2, H, CH2CF3], [AA1426; 0, N, Et, H, H, CH2CF3], [AA1427; 0, N, Et, F, H, CH2CF3], [AA1428; 0, N, Et, Cl, H, CH2CF3], [AA1429; 0, N, Et, Br, H, CH2CF3], [AA1430; 0, N, Et, I, H, CH2CF3], [AA1431; 0, N, Et, CF3, H, CH2CF3], [AA1432; 0, N, Et, CF2H, H, CH2CF3], [AA1433; 0, N, Et, C2F5, H, CH2CF3], [AA1434;[0, N, Et, C3F7, H, CH2CF3], [AA1435; 0, N, Et, CH2CF3, H, CH2CF3], [AA1436; 0, N, Et, CH2CHF2, H, CH2CF3], [AA1437; 1, N, Et, H, H, CH2CF3], [AA1438; 1, N, Et, F, H, CH2CF3], [AA1439; 1, N, Et, Cl, H, CH2CF3], [AA1440; 1, N, Et, Br, H, CH2CF3], [AA1441; 1, N, Et, I, H, CH2CF3], [AA1442; 1, N, Et, CF3, H, CH2CF3], [AA1443; 1, N, Et, CF2H, H, CH2CF3], [AA1444; 1, N, Et, C2F5, H, CH2CF3], [AA1445; 1, N, Et, C3F7, H, CH2CF3], [AA1446; 1, N, Et, CH2CF3, H, CH2CF3], [AA1447; 1, N, Et, CH2CHF2, H, CH2CF3], [AA1448; 2, N, Et, H, H, CH2CF3], [AA1449; 2, N, Et, F, H, CH2CF3], [AA1450; 2, N, Et, Cl, H, CH2CF3], [AA1451; 2, N, Et, Br, H, CH2CF3], [AA1452; 2, N, Et, I, H, CH2CF3], [AA1453; 2, N, Et, CF3, H, CH2CF3], [AA1454; 2, N, Et, CF2H, H, CH2CF3], [AA1455; 2, N, Et, C2F5, H, CH2CF3], [AA1456; 2, N, Et, C3F7, H, CH2CF3], [AA1457; 2, N, Et, CH2CF3, H, CH2CF3], [AA1458; 2, N, Et, CH2CHF2, H, CH2CF3], [AA1459; 0, CH, iPr, H, H, CH2CF3], [AA1460; 0, CH, iPr, F, H, CH2CF3], [AA1461; 0, CH, iPr, Cl, H, CH2CF3], [AA1462; 0, CH, iPr, Br, H, CH2CF3], [AA1463; 0, CH, iPr, I, H, CH2CF3], [AA1464; 0, CH, iPr, CF3, H, CH2CF3], [AA1465; 0, CH, iPr, CF2H, H, CH2CF3], [AA1466; 0, CH, iPr, C2F5, H, CH2CF3], [AA1467;[0, CH, iPr, C3F7, H, CH2CF3], [AA1468; 0, CH, iPr, CH2CF3, H, CH2CF3], [AA1469; 0, CH, iPr, CH2CHF2, H, CH2CF3], [AA1470; 1, CH, iPr, H, H, CH2CF3], [AA1471; 1, CH, iPr, F, H, CH2CF3], [AA1472; 1, CH, iPr, Cl, H, CH2CF3], [AA1473; 1, CH, iPr, Br, H, CH2CF3], [AA1474; 1, CH, iPr, I, H, CH2CF3], [AA1475; 1, CH, iPr, CF3, H, CH2CF3], [AA1476; 1, CH, iPr, CF2H, H, CH2CF3], [AA1477; 1, CH, iPr, C2F5, H, CH2CF3], [AA1478; 1, CH, iPr, C3F7, H, CH2CF3], [AA1479; 1, CH, iPr, CH2CF3, H, CH2CF3], [AA1480; 1, CH, iPr, CH2CHF2, H, CH2CF3], [AA1481; 2, CH, iPr, H, H, CH2CF3], [AA1482; 2, CH, iPr, F, H, CH2CF3], [AA1483; 2, CH, iPr, Cl, H, CH2CF3], [AA1484; 2, CH, iPr, Br, H, CH2CF3], [AA1485; 2, CH, iPr, I, H, CH2CF3], [AA1486; 2, CH, iPr, CF3, H, CH2CF3], [AA1487; 2, CH, iPr, CF2H, H, CH2CF3], [AA1488; 2, CH, iPr, C2F5, H, CH2CF3], [AA1489; 2, CH, iPr, C3F7, H, CH2CF3], [AA1490; 2, CH, iPr, CH2CF3, H, CH2CF3], [AA1491; 2, CH, iPr, CH2CHF2, H, CH2CF3], [AA1492; 0, N, iPr, H, H, CH2CF3], [AA1493; 0, N, iPr, F, H, CH2CF3], [AA1494; 0, N, iPr, Cl, H, CH2CF3], [AA1495; 0, N, iPr, Br, H, CH2CF3], [AA1496; 0, N, iPr, I, H, CH2CF3], [AA1497; 0, N, iPr, CF3, H, CH2CF3], [AA1498; 0, N, iPr, CF2H, H, CH2CF3], [AA1499;[0, N, iPr, C2F5, H, CH2CF3], [AA1500; 0, N, iPr, C3F7, H, CH2CF3], [AA1501; 0, N, iPr, CH2CF3, H, CH2CF3], [AA1502; 0, N, iPr, CH2CHF2, H, CH2CF3], [AA1503; 1, N, iPr, H, H, CH2CF3], [AA1504; 1, N, iPr, F, H, CH2CF3], [AA1505; 1, N, iPr, Cl, H, CH2CF3], [AA1506; 1, N, iPr, Br, H, CH2CF3], [AA1507; 1, N, iPr, I, H, CH2CF3], [AA1508; 1, N, iPr, CF3, H, CH2CF3], [AA1509; 1, N, iPr, CF2H, H, CH2CF3], [AA1510; 1, N, iPr, C2F5, H, CH2CF3], [AA1511; 1, N, iPr, C3F7, H, CH2CF3], [AA1512; 1, N, iPr, CH2CF3, H, CH2CF3], [AA1513; 1, N, iPr, CH2CHF2, H, CH2CF3], [AA1514; 2, N, iPr, H, H, CH2CF3], [AA1515; 2, N, iPr, F, H, CH2CF3], [AA1516; 2, N, iPr, Cl, H, CH2CF3], [AA1517; 2, N, iPr, Br, H, CH2CF3], [AA1518; 2, N, iPr, I, H, CH2CF3], [AA1519; 2, N, iPr, CF3, H, CH2CF3], [AA1520; 2, N, iPr, CF2H, H, CH2CF3], [AA1521; 2, N, iPr, C2F5, H, CH2CF3], [AA1522; 2, N, iPr, C3F7, H, CH2CF3], [AA1523; 2, N, iPr, CH2CF3, H, CH2CF3], [AA1524; 2, N, iPr, CH2CHF2, H, CH2CF3], [AA1525; 0, CH, cPr, H, H, CH2CF3], [AA1526; 0, CH, cPr, F, H, CH2CF3], [AA1527; 0, CH, cPr, Cl, H, CH2CF3], [AA1528; 0, CH, cPr, Br, H, CH2CF3], [AA1529; 0, CH, cPr, I, H, CH2CF3], [AA1530; 0, CH, cPr, CF3, H, CH2CF3], [AA1531;[[AA1532; 0, CH, cPr, CF2H, H, CH2CF3]], [[AA1533; 0, CH, cPr, C2F5, H, CH2CF3]], [[AA1534; 0, CH, cPr, C3F7, H, CH2CF3]], [[AA1535; 0, CH, cPr, CH2CF3, H, CH2CF3]], [[AA1536; 0, CH, cPr, CH2CHF2, H, CH2CF3]], [[AA1537; 1, CH, cPr, H, H, CH2CF3]], [[AA1538; 1, CH, cPr, F, H, CH2CF3]], [[AA1539; 1, CH, cPr, Cl, H, CH2CF3]], [[AA1540; 1, CH, cPr, Br, H, CH2CF3]], [[AA1541; 1, CH, cPr, I, H, CH2CF3]], [[AA1542; 1, CH, cPr, CF3, H, CH2CF3]], [[AA1543; 1, CH, cPr, CF2H, H, CH2CF3]], [[AA1544; 1, CH, cPr, C2F5, H, CH2CF3]], [[AA1545; 1, CH, cPr, C3F7, H, CH2CF3]], [[AA1546; 1, CH, cPr, CH2CF3, H, CH2CF3]], [[AA1547; 2, CH, cPr, CH2CHF2, H, CH2CF3]], [[AA1548; 2, CH, cPr, H, H, CH2CF3]], [[AA1549; 2, CH, cPr, F, H, CH2CF3]], [[AA1550; 2, CH, cPr, Cl, H, CH2CF3]], [[AA1551; 2, CH, cPr, Br, H, CH2CF3]], [[AA1552; 2, CH, cPr, I, H, CH2CF3]], [[AA1553; 2, CH, cPr, CF3, H, CH2CF3]], [[AA1554; 2, CH, cPr, CF2H, H, CH2CF3]], [[AA1555; 2, CH, cPr, C2F5, H, CH2CF3]], [[AA1556; 2, CH, cPr, C3F7, H, CH2CF3]], [[AA1557; 2, CH, cPr, CH2CF3, H, CH2CF3]], [[AA1558; 0, N, cPr, H, H, CH2CF3]], [[AA1559; 0, N, cPr, F, H, CH2CF3]], [[AA1560; 0, N, cPr, Cl, H, CH2CF3]], [[AA1561; 0, N, cPr, Br, H, CH2CF3]], [[AA1562; 0, N, cPr, I, H, CH2CF3]], [[AA1563;[0, N, cPr, CF3, H, CH2CF3], [AA1564; 0, N, cPr, CF2H, H, CH2CF3], [AA1565; 0, N, cPr, C2F5, H, CH2CF3], [AA1566; 0, N, cPr, C3F7, H, CH2CF3], [AA1567; 0, N, cPr, CH2CF3, H, CH2CF3], [AA1568; 0, N, cPr, CH2CHF2, H, CH2CF3], [AA1569; 1, N, cPr, H, H, CH2CF3], [AA1570; 1, N, cPr, F, H, CH2CF3], [AA1571; 1, N, cPr, Cl, H, CH2CF3], [AA1572; 1, N, cPr, Br, H, CH2CF3], [AA1573; 1, N, cPr, I, H, CH2CF3], [AA1574; 1, N, cPr, CF3, H, CH2CF3], [AA1575; 1, N, cPr, CF2H, H, CH2CF3], [AA1576; 1, N, cPr, C2F5, H, CH2CF3], [AA1577; 1, N, cPr, C3F7, H, CH2CF3], [AA1578; 1, N, cPr, CH2CF3, H, CH2CF3], [AA1579; 1, N, cPr, CH2CHF2, H, CH2CF3], [AA1580; 2, N, cPr, H, H, CH2CF3], [AA1581; 2, N, cPr, F, H, CH2CF3], [AA1582; 2, N, cPr, Cl, H, CH2CF3], [AA1583; 2, N, cPr, Br, H, CH2CF3], [AA1584; 2, N, cPr, I, H, CH2CF3], [AA1585; 2, N, cPr, CF3, H, CH2CF3], [AA1586; 2, N, cPr, CF2H, H, CH2CF3], [AA1587; 2, N, cPr, C2F5, H, CH2CF3], [AA1588; 2, N, cPr, C3F7, H, CH2CF3], [AA1589; 2, N, cPr, CH2CF3, H, CH2CF3], [AA1590; 2, N, cPr, CH2CHF2, H, CH2CF3], [AA1591; 0, CH, H, H, F, CH2CF3], [AA1592; 0, CH, H, H, Cl, CH2CF3], [AA1593; 0, CH, H, H, Br, CH2CF3], [AA1594; 0, CH, H, H, I, CH2CF3], [AA1595; 0, CH, H, H, CF3, CH2CF3], [AA1596;[0, CH, H, H, CF2H, CH2CF3], [AA1597; 0, CH, H, H, C2F5, CH2CF3], [AA1598; 0, CH, H, H, C3F7, CH2CF3], [AA1599; 0, CH, H, H, CH2CF3, CH2CF3], [AA1600; 0, CH, H, H, CH2CHF2, CH2CF3], [AA1601; 1, CH, H, H, F, CH2CF3], [AA1602; 1, CH, H, H, Cl, CH2CF3], [AA1603; 1, CH, H, H, Br, CH2CF3], [AA1604; 1, CH, H, H, I, CH2CF3], [AA1605; 1, CH, H, H, CF3, CH2CF3], [AA1606; 1, CH, H, H, CF2H, CH2CF3], [AA1607; 1, CH, H, H, C2F5, CH2CF3], [AA1608; 1, CH, H, H, C3F7, CH2CF3], [AA1609; 1, CH, H, H, CH2CF3, CH2CF3], [AA1610; 1, CH, H, H, CH2CHF2, CH2CF3], [AA1611; 2, CH, H, H, F, CH2CF3], [AA1612; 2, CH, H, H, Cl, CH2CF3], [AA1613; 2, CH, H, H, Br, CH2CF3], [AA1614; 2, CH, H, H, I, CH2CF3], [AA1615; 2, CH, H, H, CF3, CH2CF3], [AA1616; 2, CH, H, H, CF2H, CH2CF3], [AA1617; 2, CH, H, H, C2F5, CH2CF3], [AA1618; 2, CH, H, H, C3F7, CH2CF3], [AA1619; 2, CH, H, H, CH2CF3, CH2CF3], [AA1620; 2, CH, H, H, CH2CHF2, CH2CF3], [AA1621; 0, N, H, H, F, CH2CF3], [AA1622; 0, N, H, H, Cl, CH2CF3], [AA1623; 0, N, H, H, Br, CH2CF3], [AA1624; 0, N, H, H, I, CH2CF3], [AA1625; 0, N, H, H, CF3, CH2CF3], [AA1626; 0, N, H, H, CF2H, CH2CF3], [AA1627; 0, N, H, H, C2F5, CH2CF3], [AA1628; 0, N, H, H, C3F7, CH2CF3], [AA1629; 0, N, H, H, CH2CF3, CH2CF3], [AA1630;[0, N, H, H, CH2CHF2, CH2CF3], [AA1631; 1, N, H, H, F, CH2CF3], [AA1632; 1, N, H, H, Cl, CH2CF3], [AA1633; 1, N, H, H, Br, CH2CF3], [AA1634; 1, N, H, H, I, CH2CF3], [AA1635; 1, N, H, H, CF3, CH2CF3], [AA1636; 1, N, H, H, CF2H, CH2CF3], [AA1637; 1, N, H, H, C2F5, CH2CF3], [AA1638; 1, N, H, H, C3F7, CH2CF3], [AA1639; 1, N, H, H, CH2CF3, CH2CF3], [AA1640; 1, N, H, H, CH2CHF2, CH2CF3], [AA1641; 2, N, H, H, F, CH2CF3], [AA1642; 2, N, H, H, Cl, CH2CF3], [AA1643; 2, N, H, H, Br, CH2CF3], [AA1644; 2, N, H, H, I, CH2CF3], [AA1645; 2, N, H, H, CF3, CH2CF3], [AA1646; 2, N, H, H, CF2H, CH2CF3], [AA1647; 2, N, H, H, C2F5, CH2CF3], [AA1648; 2, N, H, H, C3F7, CH2CF3], [AA1649; 2, N, H, H, CH2CF3, CH2CF3], [AA1650; 2, N, H, H, CH2CHF2, CH2CF3], [AA1651; 0, CH, Me, H, F, CH2CF3], [AA1652; 0, CH, Me, H, Cl, CH2CF3], [AA1653; 0, CH, Me, H, Br, CH2CF3], [AA1654; 0, CH, Me, H, I, CH2CF3], [AA1655; 0, CH, Me, H, CF3, CH2CF3], [AA1656; 0, CH, Me, H, CF2H, CH2CF3], [AA1657; 0, CH, Me, H, C2F5, CH2CF3], [AA1658; 0, CH, Me, H, C3F7, CH2CF3], [AA1659; 0, CH, Me, H, CH2CF3, CH2CF3], [AA1660; 0, CH, Me, H, CH2CHF2, CH2CF3], [AA1661; 1, CH, Me, H, F, CH2CF3], [AA1662; 1, CH, Me, H, Cl, CH2CF3], [AA1663; 1, CH, Me, H, Br, CH2CF3], [AA1664;1,CH,Me,H,I,CH2CF3], [AA1665; 1,CH,Me,H,CF3,CH2CF3], [AA1666; 1,CH,Me,H,CF2H,CH2CF3], [AA1667; 1,CH,Me,H,C2F5,CH2CF3], [AA1668; 1,CH,Me,H,C3F7,CH2CF3], [AA1669; 1,CH,Me,H,CH2CF3,CH2CF3], [AA1670; 1,CH,Me,H,CH2CHF2,CH2CF3], [AA1671; 2,CH,Me,H,F,CH2CF3], [AA1672; 2,CH,Me,H,Cl,CH2CF3], [AA1673; 2,CH,Me,H,Br,CH2CF3], [AA1674; 2,CH,Me,H,I,CH2CF3], [AA1675; 2,CH,Me,H,CF3,CH2CF3], [AA1676; 2,CH,Me,H,CF2H,CH2CF3], [AA1677; 2,CH,Me,H,C2F5,CH2CF3], [AA1678; 2,CH,Me,H,C3F7,CH2CF3], [AA1679; 2,CH,Me,H,CH2CF3,CH2CF3], [AA1680; 2,CH,Me,H,CH2CHF2,CH2CF3], [AA1681; 0,N,Me,H,F,CH2CF3], [AA1682; 0,N,Me,H,Cl,CH2CF3], [AA1683; 0,N,Me,H,Br,CH2CF3], [AA1684; 0,N,Me,H,I,CH2CF3], [AA1685; 0,N,Me,H,CF3,CH2CF3], [AA1686; 0,N,Me,H,CF2H,CH2CF3], [AA1687; 0,N,Me,H,C2F5,CH2CF3], [AA1688; 0,N,Me,H,C3F7,CH2CF3], [AA1689; 0,N,Me,H,CH2CF3,CH2CF3], [AA1690; 0,N,Me,H,CH2CHF2,CH2CF3], [AA1691; 1,N,Me,H,F,CH2CF3], [AA1692; 1,N,Me,H,Cl,CH2CF3], [AA1693; 1,N,Me,H,Br,CH2CF3], [AA1694; 1,N,Me,H,I,CH2CF3], [AA1695; 1,N,Me,H,CF3,CH2CF3], [AA1696; 1,N,Me,H,CF2H,CH2CF3], [AA1697;[1,N,Me,H,C2F5,CH2CF3], [AA1698; 1,N,Me,H,C3F7,CH2CF3], [AA1699; 1,N,Me,H,CH2CF3,CH2CF3], [AA1700; 1,N,Me,H,CH2CHF2,CH2CF3], [AA1701; 2,N,Me,H,F,CH2CF3], [AA1702; 2,N,Me,H,Cl,CH2CF3], [AA1703; 2,N,Me,H,Br,CH2CF3], [AA1704; 2,N,Me,H,I,CH2CF3], [AA1705; 2,N,Me,H,CF3,CH2CF3], [AA1706; 2,N,Me,H,CF2H,CH2CF3], [AA1707; 2,N,Me,H,C2F5,CH2CF3], [AA1708; 2,N,Me,H,C3F7,CH2CF3], [AA1709; 2,N,Me,H,CH2CF3,CH2CF3], [AA1710; 2,N,Me,H,CH2CHF2,CH2CF3], [AA1711; 0,CH,Et,H,F,CH2CF3], [AA1712; 0,CH,Et,H,Cl,CH2CF3], [AA1713; 0,CH,Et,H,Br,CH2CF3], [AA1714; 0,CH,Et,H,I,CH2CF3], [AA1715; 0,CH,Et,H,CF3,CH2CF3], [AA1716; 0,CH,Et,H,CF2H,CH2CF3], [AA1717; 0,CH,Et,H,C2F5,CH2CF3], [AA1718; 0,CH,Et,H,C3F7,CH2CF3], [AA1719; 0,CH,Et,H,CH2CF3,CH2CF3], [AA1720; 0,CH,Et,H,CH2CHF2,CH2CF3], [AA1721; 1,CH,Et,H,F,CH2CF3], [AA1722; 1,CH,Et,H,Cl,CH2CF3], [AA1723; 1,CH,Et,H,Br,CH2CF3], [AA1724; 1,CH,Et,H,I,CH2CF3], [AA1725; 1,CH,Et,H,CF3,CH2CF3], [AA1726; 1,CH,Et,H,CF2H,CH2CF3], [AA1727; 1,CH,Et,H,C2F5,CH2CF3], [AA1728; 1,CH,Et,H,C3F7,CH2CF3], [AA1729; 1,CH,Et,H,CH2CF3,CH2CF3], [AA1730;[1, CH, Et, H, CH2CHF2, CH2CF3], [AA1731; 2, CH, Et, H, F, CH2CF3], [AA1732; 2, CH, Et, H, Cl, CH2CF3], [AA1733; 2, CH, Et, H, Br, CH2CF3], [AA1734; 2, CH, Et, H, I, CH2CF3], [AA1735; 2, CH, Et, H, CF3, CH2CF3], [AA1736; 2, CH, Et, H, CF2H, CH2CF3], [AA1737; 2, CH, Et, H, C2F5, CH2CF3], [AA1738; 2, CH, Et, H, C3F7, CH2CF3], [AA1739; 2, CH, Et, H, CH2CF3, CH2CF3], [AA1740; 2, CH, Et, H, CH2CHF2, CH2CF3], [AA1741; 0, N, Et, H, F, CH2CF3], [AA1742; 0, N, Et, H, Cl, CH2CF3], [AA1743; 0, N, Et, H, Br, CH2CF3], [AA1744; 0, N, Et, H, I, CH2CF3], [AA1745; 0, N, Et, H, CF3, CH2CF3], [AA1746; 0, N, Et, H, CF2H, CH2CF3], [AA1747; 0, N, Et, H, C2F5, CH2CF3], [AA1748; 0, N, Et, H, C3F7, CH2CF3], [AA1749; 0, N, Et, H, CH2CF3, CH2CF3], [AA1750; 0, N, Et, H, CH2CHF2, CH2CF3], [AA1751; 1, N, Et, H, F, CH2CF3], [AA1752; 1, N, Et, H, Cl, CH2CF3], [AA1753; 1, N, Et, H, Br, CH2CF3], [AA1754; 1, N, Et, H, I, CH2CF3], [AA1755; 1, N, Et, H, CF3, CH2CF3], [AA1756; 1, N, Et, H, CF2H, CH2CF3], [AA1757; 1, N, Et, H, C2F5, CH2CF3], [AA1758; 1, N, Et, H, C3F7, CH2CF3], [AA1759; 1, N, Et, H, CH2CF3, CH2CF3], [AA1760; 1, N, Et, H, CH2CHF2, CH2CF3], [AA1761; 2, N, Et, H, F, CH2CF3], [AA1762; 2, N, Et, H, Cl, CH2CF3], [AA1763;[2,N,Et,H,Br,CH2CF3], [AA1764; 2,N,Et,H,I,CH2CF3], [AA1765; 2,N,Et,H,CF3,CH2CF3], [AA1766; 2,N,Et,H,CF2H,CH2CF3], [AA1767; 2,N,Et,H,C2F5,CH2CF3], [AA1768; 2,N,Et,H,C3F7,CH2CF3], [AA1769; 2,N,Et,H,CH2CF3,CH2CF3], [AA1770; 2,N,Et,H,CH2CHF2,CH2CF3], [AA1771; 0,CH,iPr,H,F,CH2CF3], [AA1772; 0,CH,iPr,H,Cl,CH2CF3], [AA1773; 0,CH,iPr,H,Br,CH2CF3], [AA1774; 0,CH,iPr,H,I,CH2CF3], [AA1775; 0,CH,iPr,H,CF3,CH2CF3], [AA1776; 0,CH,iPr,H,CF2H,CH2CF3], [AA1777; 0,CH,iPr,H,C2F5,CH2CF3], [AA1778; 0,CH,iPr,H,C3F7,CH2CF3], [AA1779; 0,CH,iPr,H,CH2CF3,CH2CF3], [AA1780; 0,CH,iPr,H,CH2CHF2,CH2CF3], [AA1781; 1,CH,iPr,H,F,CH2CF3], [AA1782; 1,CH,iPr,H,Cl,CH2CF3], [AA1783; 1,CH,iPr,H,Br,CH2CF3], [AA1784; 1,CH,iPr,H,I,CH2CF3], [AA1785; 1,CH,iPr,H,CF3,CH2CF3], [AA1786; 1,CH,iPr,H,CF2H,CH2CF3], [AA1787; 1,CH,iPr,H,C2F5,CH2CF3], [AA1788; 1,CH,iPr,H,C3F7,CH2CF3], [AA1789; 1,CH,iPr,H,CH2CF3,CH2CF3], [AA1790; 1,CH,iPr,H,CH2CHF2,CH2CF3], [AA1791; 2,CH,iPr,H,F,CH2CF3], [AA1792; 2,CH,iPr,H,Cl,CH2CF3], [AA1793; 2,CH,iPr,H,Br,CH2CF3], [AA1794; 2,CH,iPr,H,I,CH2CF3], [AA1795;[2, CH, iPr, H, CF3, CH2CF3], [AA1796; 2, CH, iPr, H, CF2H, CH2CF3], [AA1797; 2, CH, iPr, H, C2F5, CH2CF3], [AA1798; 2, CH, iPr, H, C3F7, CH2CF3], [AA1799; 2, CH, iPr, H, CH2CF3, CH2CF3], [AA1800; 2, CH, iPr, H, CH2CHF2, CH2CF3], [AA1801; 0, N, iPr, H, F, CH2CF3], [AA1802; 0, N, iPr, H, Cl, CH2CF3], [AA1803; 0, N, iPr, H, Br, CH2CF3], [AA1804; 0, N, iPr, H, I, CH2CF3], [AA1805; 0, N, iPr, H, CF3, CH2CF3], [AA1806; 0, N, iPr, H, CF2H, CH2CF3], [AA1807; 0, N, iPr, H, C2F5, CH2CF3], [AA1808; 0, N, iPr, H, C3F7, CH2CF3], [AA1809; 0, N, iPr, H, CH2CF3, CH2CF3], [AA1810; 0, N, iPr, H, CH2CHF2, CH2CF3], [AA1811; 1, N, iPr, H, F, CH2CF3], [AA1812; 1, N, iPr, H, Cl, CH2CF3], [AA1813; 1, N, iPr, H, Br, CH2CF3], [AA1814; 1, N, iPr, H, I, CH2CF3], [AA1815; 1, N, iPr, H, CF3, CH2CF3], [AA1816; 1, N, iPr, H, CF2H, CH2CF3], [AA1817; 1, N, iPr, H, C2F5, CH2CF3], [AA1818; 1, N, iPr, H, C3F7, CH2CF3], [AA1819; 1, N, iPr, H, CH2CF3, CH2CF3], [AA1820; 1, N, iPr, H, CH2CHF2, CH2CF3], [AA1821; 2, N, iPr, H, F, CH2CF3], [AA1822; 2, N, iPr, H, Cl, CH2CF3], [AA1823; 2, N, iPr, H, Br, CH2CF3], [AA1824; 2, N, iPr, H, I, CH2CF3], [AA1825; 2, N, iPr, H, CF3, CH2CF3], [AA1826; 2, N, iPr, H, CF2H, CH2CF3], [AA1827;[2,N,iPr,H,C2F5,CH2CF3], [AA1828; 2,N,iPr,H,C3F7,CH2CF3], [AA1829; 2,N,iPr,H,CH2CF3,CH2CF3], [AA1830; 2,N,iPr,H,CH2CHF2,CH2CF3], [AA1831; 0,CH,cPr,H,F,CH2CF3], [AA1832; 0,CH,cPr,H,Cl,CH2CF3], [AA1833; 0,CH,cPr,H,Br,CH2CF3], [AA1834; 0,CH,cPr,H,I,CH2CF3], [AA1835; 0,CH,cPr,H,CF3,CH2CF3], [AA1836; 0,CH,cPr,H,CF2H,CH2CF3], [AA1837; 0,CH,cPr,H,C2F5,CH2CF3], [AA1838; 0,CH,cPr,H,C3F7,CH2CF3], [AA1839; 0,CH,cPr,H,CH2CF3,CH2CF3], [AA1840; 0,CH,cPr,H,CH2CHF2,CH2CF3], [AA1841; 1,CH,cPr,H,F,CH2CF3], [AA1842; 1,CH,cPr,H,Cl,CH2CF3], [AA1843; 1,CH,cPr,H,Br,CH2CF3], [AA1844; 1,CH,cPr,H,I,CH2CF3], [AA1845; 1,CH,cPr,H,CF3,CH2CF3], [AA1846; 1,CH,cPr,H,CF2H,CH2CF3], [AA1847; 1,CH,cPr,H,C2F5,CH2CF3], [AA1848; 1,CH,cPr,H,C3F7,CH2CF3], [AA1849; 1,CH,cPr,H,CH2CF3,CH2CF3], [AA1850; 1,CH,cPr,H,CH2CHF2,CH2CF3], [AA1851; 2,CH,cPr,H,F,CH2CF3], [AA1852; 2,CH,cPr,H,Cl,CH2CF3], [AA1853; 2,CH,cPr,H,Br,CH2CF3], [AA1854; 2,CH,cPr,H,I,CH2CF3], [AA1855; 2,CH,cPr,H,CF3,CH2CF3], [AA1856; 2,CH,cPr,H,CF2H,CH2CF3], [AA1857; 2,CH,cPr,H,C2F5,CH2CF3], [AA1858;[2,CH,cPr,H,C3F7,CH2CF3], [AA1859; 2,CH,cPr,H,CH2CF3,CH2CF3], [AA1860; 2,CH,cPr,H,CH2CHF2,CH2CF3], [AA1861; 0,N,cPr,H,F,CH2CF3], [AA1862; 0,N,cPr,H,Cl,CH2CF3], [AA1863; 0,N,cPr,H,Br,CH2CF3], [AA1864; 0,N,cPr,H,I,CH2CF3], [AA1865; 0,N,cPr,H,CF3,CH2CF3], [AA1866; 0,N,cPr,H,CF2H,CH2CF3], [AA1867; 0,N,cPr,H,C2F5,CH2CF3], [AA1868; 0,N,cPr,H,C3F7,CH2CF3], [AA1869; 0,N,cPr,H,CH2CF3,CH2CF3], [AA1870; 0,N,cPr,H,CH2CHF2,CH2CF3], [AA1871; 1,N,cPr,H,F,CH2CF3], [AA1872; 1,N,cPr,H,Cl,CH2CF3], [AA1873; 1,N,cPr,H,Br,CH2CF3], [AA1874; 1,N,cPr,H,I,CH2CF3], [AA1875; 1,N,cPr,H,CF3,CH2CF3], [AA1876; 1,N,cPr,H,CF2H,CH2CF3], [AA1877; 1,N,cPr,H,C2F5,CH2CF3], [AA1878; 1,N,cPr,H,C3F7,CH2CF3], [AA1879; 1,N,cPr,H,CH2CF3,CH2CF3], [AA1880; 1,N,cPr,H,CH2CHF2,CH2CF3], [AA1881; 2,N,cPr,H,F,CH2CF3], [AA1882; 2,N,cPr,H,Cl,CH2CF3], [AA1883; 2,N,cPr,H,Br,CH2CF3], [AA1884; 2,N,cPr,H,I,CH2CF3], [AA1885; 2,N,cPr,H,CF3,CH2CF3], [AA1886; 2,N,cPr,H,CF2H,CH2CF3], [AA1887; 2,N,cPr,H,C2F5,CH2CF3], [AA1888; 2,N,cPr,H,C3F7,CH2CF3], [AA1889; 2,N,cPr,H,CH2CF3,CH2CF3], [AA1890;[2,N,cPr,H,CH2CHF2,CH2CF3], [AA1891; 0,CH,H,H,H,CH2CHF2], [AA1892; 0,CH,H,F,H,CH2CHF2], [AA1893; 0,CH,H,Cl,H,CH2CHF2], [AA1894; 0,CH,H,Br,H,CH2CHF2], [AA1895; 0,CH,H,I,H,CH2CHF2], [AA1896; 0,CH,H,CF3,H,CH2CHF2], [AA1897; 0,CH,H,CF2H,H,CH2CHF2], [AA1898; 0,CH,H,C2F5,H,CH2CHF2], [AA1899; 0,CH,H,C3F7,H,CH2CHF2], [AA1900; 0,CH,H,CH2CF3,H,CH2CHF2], [AA1901; 0,CH,H,CH2CHF2,H,CH2CHF2], [AA1902; 1,CH,H,H,H,CH2CHF2], [AA1903; 1,CH,H,F,H,CH2CHF2], [AA1904; 1,CH,H,Cl,H,CH2CHF2], [AA1905; 1,CH,H,Br,H,CH2CHF2], [AA1906; 1,CH,H,I,H,CH2CHF2], [AA1907; 1,CH,H,CF3,H,CH2CHF2], [AA1908; 1,CH,H,CF2H,H,CH2CHF2], [AA1909; 1,CH,H,C2F5,H,CH2CHF2], [AA1910; 1,CH,H,C3F7,H,CH2CHF2], [AA1911; 1,CH,H,CH2CF3,H,CH2CHF2], [AA1912; 1,CH,H,CH2CHF2,H,CH2CHF2], [AA1913; 2,CH,H,H,H,CH2CHF2], [AA1914; 2,CH,H,F,H,CH2CHF2], [AA1915; 2,CH,H,Cl,H,CH2CHF2], [AA1916; 2,CH,H,Br,H,CH2CHF2], [AA1917; 2,CH,H,I,H,CH2CHF2], [AA1918; 2,CH,H,CF3,H,CH2CHF2], [AA1919; 2,CH,H,CF2H,H,CH2CHF2], [AA1920; 2,CH,H,C2F5,H,CH2CHF2], [AA1921; 2,CH,H,C3F7,H,CH2CHF2], [AA1922; 2,CH,H,CH2CF3,H,CH2CHF2], [AA1923;[2,CH,H,CH2CHF2,H,CH2CHF2], [AA1924; 0,N,H,H,H,CH2CHF2], [AA1925; 0,N,H,F,H,CH2CHF2], [AA1926; 0,N,H,Cl,H,CH2CHF2], [AA1927; 0,N,H,Br,H,CH2CHF2], [AA1928; 0,N,H,I,H,CH2CHF2], [AA1929; 0,N,H,CF3,H,CH2CHF2], [AA1930; 0,N,H,CF2H,H,CH2CHF2], [AA1931; 0,N,H,C2F5,H,CH2CHF2], [AA1932; 0,N,H,C3F7,H,CH2CHF2], [AA1933; 0,N,H,CH2CF3,H,CH2CHF2], [AA1934; 0,N,H,CH2CHF2,H,CH2CHF2], [AA1935; 1,N,H,H,H,CH2CHF2], [AA1936; 1,N,H,F,H,CH2CHF2], [AA1937; 1,N,H,Cl,H,CH2CHF2], [AA1938; 1,N,H,Br,H,CH2CHF2], [AA1939; 1,N,H,I,H,CH2CHF2], [AA1940; 1,N,H,CF3,H,CH2CHF2], [AA1941; 1,N,H,CF2H,H,CH2CHF2], [AA1942; 1,N,H,C2F5,H,CH2CHF2], [AA1943; 1,N,H,C3F7,H,CH2CHF2], [AA1944; 1,N,H,CH2CF3,H,CH2CHF2], [AA1945; 1,N,H,CH2CHF2,H,CH2CHF2], [AA1946; 2,N,H,H,H,CH2CHF2], [AA1947; 2,N,H,F,H,CH2CHF2], [AA1948; 2,N,H,Cl,H,CH2CHF2], [AA1949; 2,N,H,Br,H,CH2CHF2], [AA1950; 2,N,H,I,H,CH2CHF2], [AA1951; 2,N,H,CF3,H,CH2CHF2], [AA1952; 2,N,H,CF2H,H,CH2CHF2], [AA1953; 2,N,H,C2F5,H,CH2CHF2], [AA1954; 2,N,H,C3F7,H,CH2CHF2], [AA1955; 2,N,H,CH2CF3,H,CH2CHF2], [AA1956; 2,N,H,CH2CHF2,H,CH2CHF2], [AA1957;0, CH, Me, H, H, CH2CHF2], [AA1958; 0, CH, Me, F, H, CH2CHF2], [AA1959; 0, CH, Me, Cl, H, CH2CHF2], [AA1960; 0, CH, Me, Br, H, CH2CHF2], [AA1961; 0, CH, Me, I, H, CH2CHF2], [AA1962; 0, CH, Me, CF3, H, CH2CHF2], [AA1963; 0, CH, Me, CF2H, H, CH2CHF2], [AA1964; 0, CH, Me, C2F5, H, CH2CHF2], [AA1965; 0, CH, Me, C3F7, H, CH2CHF2], [AA1966; 0, CH, Me, CH2CF3, H, CH2CHF2], [AA1967; 0, CH, Me, CH2CHF2, H, CH2CHF2], [AA1968; 1, CH, Me, H, H, CH2CHF2], [AA1969; 1, CH, Me, F, H, CH2CHF2], [AA1970; 1, CH, Me, Cl, H, CH2CHF2], [AA1971; 1, CH, Me, Br, H, CH2CHF2], [AA1972; 1, CH, Me, I, H, CH2CHF2], [AA1973; 1, CH, Me, CF3, H, CH2CHF2], [AA1974; 1, CH, Me, CF2H, H, CH2CHF2], [AA1975; 1, CH, Me, C2F5, H, CH2CHF2], [AA1976; 1, CH, Me, C3F7, H, CH2CHF2], [AA1977; 1, CH, Me, CH2CF3, H, CH2CHF2], [AA1978; 1, CH, Me, CH2CHF2, H, CH2CHF2], [AA1979; 2, CH, Me, H, H, CH2CHF2], [AA1980; 2, CH, Me, F, H, CH2CHF2], [AA1981; 2, CH, Me, Cl, H, CH2CHF2], [AA1982; 2, CH, Me, Br, H, CH2CHF2], [AA1983; 2, CH, Me, I, H, CH2CHF2], [AA1984; 2, CH, Me, CF3, H, CH2CHF2], [AA1985; 2, CH, Me, CF2H, H, CH2CHF2], [AA1986; 2, CH, Me, C2F5, H, CH2CHF2], [AA1987; 2, CH, Me, C3F7, H, CH2CHF2], [AA1988; 2, CH, Me, CH2CF3, H, CH2CHF2], [AA1989;[2,CH,Me,CH2CHF2,H,CH2CHF2], [AA1990; 0,N,Me,H,H,CH2CHF2], [AA1991; 0,N,Me,F,H,CH2CHF2], [AA1992; 0,N,Me,Cl,H,CH2CHF2], [AA1993; 0,N,Me,Br,H,CH2CHF2], [AA1994; 0,N,Me,I,H,CH2CHF2], [AA1995; 0,N,Me,CF3,H,CH2CHF2], [AA1996; 0,N,Me,CF2H,H,CH2CHF2], [AA1997; 0,N,Me,C2F5,H,CH2CHF2], [AA1998; 0,N,Me,C3F7,H,CH2CHF2], [AA1999; 0,N,Me,CH2CF3,H,CH2CHF2], [AA2000; 0,N,Me,CH2CHF2,H,CH2CHF2], [AA2001; 1,N,Me,H,H,CH2CHF2], [AA2002; 1,N,Me,F,H,CH2CHF2], [AA2003; 1,N,Me,Cl,H,CH2CHF2], [AA2004; 1,N,Me,Br,H,CH2CHF2], [AA2005; 1,N,Me,I,H,CH2CHF2], [AA2006; 1,N,Me,CF3,H,CH2CHF2], [AA2007; 1,N,Me,CF2H,H,CH2CHF2], [AA2008; 1,N,Me,C2F5,H,CH2CHF2], [AA2009; 1,N,Me,C3F7,H,CH2CHF2], [AA2010; 1,N,Me,CH2CF3,H,CH2CHF2], [AA2011; 1,N,Me,CH2CHF2,H,CH2CHF2], [AA2012; 2,N,Me,H,H,CH2CHF2], [AA2013; 2,N,Me,F,H,CH2CHF2], [AA2014; 2,N,Me,Cl,H,CH2CHF2], [AA2015; 2,N,Me,Br,H,CH2CHF2], [AA2016; 2,N,Me,I,H,CH2CHF2], [AA2017; 2,N,Me,CF3,H,CH2CHF2], [AA2018; 2,N,Me,CF2H,H,CH2CHF2], [AA2019; 2,N,Me,C2F5,H,CH2CHF2], [AA2020; 2,N,Me,C3F7,H,CH2CHF2], [AA2021; 2,N,Me,CH2CF3,H,CH2CHF2], [AA2022;[2,N,Me,CH2CHF2,H,CH2CHF2], [AA2023; 0,CH,Et,H,H,CH2CHF2], [AA2024; 0,CH,Et,F,H,CH2CHF2], [AA2025; 0,CH,Et,Cl,H,CH2CHF2], [AA2026; 0,CH,Et,Br,H,CH2CHF2], [AA2027; 0,CH,Et,I,H,CH2CHF2], [AA2028; 0,CH,Et,CF3,H,CH2CHF2], [AA2029; 0,CH,Et,CF2H,H,CH2CHF2], [AA2030; 0,CH,Et,C2F5,H,CH2CHF2], [AA2031; 0,CH,Et,C3F7,H,CH2CHF2], [AA2032; 0,CH,Et,CH2CF3,H,CH2CHF2], [AA2033; 0,CH,Et,CH2CHF2,H,CH2CHF2], [AA2034; 1,CH,Et,H,H,CH2CHF2], [AA2035; 1,CH,Et,F,H,CH2CHF2], [AA2036; 1,CH,Et,Cl,H,CH2CHF2], [AA2037; 1,CH,Et,Br,H,CH2CHF2], [AA2038; 1,CH,Et,I,H,CH2CHF2], [AA2039; 1,CH,Et,CF3,H,CH2CHF2], [AA2040; 1,CH,Et,CF2H,H,CH2CHF2], [AA2041; 1,CH,Et,C2F5,H,CH2CHF2], [AA2042; 1,CH,Et,C3F7,H,CH2CHF2], [AA2043; 1,CH,Et,CH2CF3,H,CH2CHF2], [AA2044; 1,CH,Et,CH2CHF2,H,CH2CHF2], [AA2045; 2,CH,Et,H,H,CH2CHF2], [AA2046; 2,CH,Et,F,H,CH2CHF2], [AA2047; 2,CH,Et,Cl,H,CH2CHF2], [AA2048; 2,CH,Et,Br,H,CH2CHF2], [AA2049; 2,CH,Et,I,H,CH2CHF2], [AA2050; 2,CH,Et,CF3,H,CH2CHF2], [AA2051; 2,CH,Et,CF2H,H,CH2CHF2], [AA2052; 2,CH,Et,C2F5,H,CH2CHF2], [AA2053; 2,CH,Et,C3F7,H,CH2CHF2], [AA2054;[2, CH, Et, CH2CF3, H, CH2CHF2], [AA2055; 2, CH, Et, CH2CHF2, H, CH2CHF2], [AA2056; 0, N, Et, H, H, CH2CHF2], [AA2057; 0, N, Et, F, H, CH2CHF2], [AA2058; 0, N, Et, Cl, H, CH2CHF2], [AA2059; 0, N, Et, Br, H, CH2CHF2], [AA2060; 0, N, Et, I, H, CH2CHF2], [AA2061; 0, N, Et, CF3, H, CH2CHF2], [AA2062; 0, N, Et, CF2H, H, CH2CHF2], [AA2063; 0, N, Et, C2F5, H, CH2CHF2], [AA2064; 0, N, Et, C3F7, H, CH2CHF2], [AA2065; 0, N, Et, CH2CF3, H, CH2CHF2], [AA2066; 0, N, Et, CH2CHF2, H, CH2CHF2], [AA2067; 1, N, Et, H, H, CH2CHF2], [AA2068; 1, N, Et, F, H, CH2CHF2], [AA2069; 1, N, Et, Cl, H, CH2CHF2], [AA2070; 1, N, Et, Br, H, CH2CHF2], [AA2071; 1, N, Et, I, H, CH2CHF2], [AA2072; 1, N, Et, CF3, H, CH2CHF2], [AA2073; 1, N, Et, CF2H, H, CH2CHF2], [AA2074; 1, N, Et, C2F5, H, CH2CHF2], [AA2075; 1, N, Et, C3F7, H, CH2CHF2], [AA2076; 1, N, Et, CH2CF3, H, CH2CHF2], [AA2077; 1, N, Et, CH2CHF2, H, CH2CHF2], [AA2078; 2, N, Et, H, H, CH2CHF2], [AA2079; 2, N, Et, F, H, CH2CHF2], [AA2080; 2, N, Et, Cl, H, CH2CHF2], [AA2081; 2, N, Et, Br, H, CH2CHF2], [AA2082; 2, N, Et, I, H, CH2CHF2], [AA2083; 2, N, Et, CF3, H, CH2CHF2], [AA2084; 2, N, Et, CF2H, H, CH2CHF2], [AA2085; 2, N, Et, C2F5, H, CH2CHF2], [AA2086; 2, N, Et, C3F7, H, CH2CHF2], [AA2087;[2,N,Et,CH2CF3,H,CH2CHF2], [AA2088; 2,N,Et,CH2CHF2,H,CH2CHF2], [AA2089; 0,CH,iPr,H,H,CH2CHF2], [AA2090; 0,CH,iPr,F,H,CH2CHF2], [AA2091; 0,CH,iPr,Cl,H,CH2CHF2], [AA2092; 0,CH,iPr,Br,H,CH2CHF2], [AA2093; 0,CH,iPr,I,H,CH2CHF2], [AA2094; 0,CH,iPr,CF3,H,CH2CHF2], [AA2095; 0,CH,iPr,CF2H,H,CH2CHF2], [AA2096; 0,CH,iPr,C2F5,H,CH2CHF2], [AA2097; 0,CH,iPr,C3F7,H,CH2CHF2], [AA2098; 0,CH,iPr,CH2CF3,H,CH2CHF2], [AA2099; 0,CH,iPr,CH2CHF2,H,CH2CHF2], [AA2100; 1,CH,iPr,H,H,CH2CHF2], [AA2101; 1,CH,iPr,F,H,CH2CHF2], [AA2102; 1,CH,iPr,Cl,H,CH2CHF2], [AA2103; 1,CH,iPr,Br,H,CH2CHF2], [AA2104; 1,CH,iPr,I,H,CH2CHF2], [AA2105; 1,CH,iPr,CF3,H,CH2CHF2], [AA2106; 1,CH,iPr,CF2H,H,CH2CHF2], [AA2107; 1,CH,iPr,C2F5,H,CH2CHF2], [AA2108; 1,CH,iPr,C3F7,H,CH2CHF2], [AA2109; 1,CH,iPr,CH2CF3,H,CH2CHF2], [AA2110; 1,CH,iPr,CH2CHF2,H,CH2CHF2], [AA2111; 2,CH,iPr,H,H,CH2CHF2], [AA2112; 2,CH,iPr,F,H,CH2CHF2], [AA2113; 2,CH,iPr,Cl,H,CH2CHF2], [AA2114; 2,CH,iPr,Br,H,CH2CHF2], [AA2115; 2,CH,iPr,I,H,CH2CHF2], [AA2116; 2,CH,iPr,CF3,H,CH2CHF2], [AA2117; 2,CH,iPr,CF2H,H,CH2CHF2], [AA2118;[2, CH, iPr, C2F5, H, CH2CHF2], [AA2119; 2, CH, iPr, C3F7, H, CH2CHF2], [AA2120; 2, CH, iPr, CH2CF3, H, CH2CHF2], [AA2121; 2, CH, iPr, CH2CHF2, H, CH2CHF2], [AA2122; 0, N, iPr, H, H, CH2CHF2], [AA2123; 0, N, iPr, F, H, CH2CHF2], [AA2124; 0, N, iPr, Cl, H, CH2CHF2], [AA2125; 0, N, iPr, Br, H, CH2CHF2], [AA2126; 0, N, iPr, I, H, CH2CHF2], [AA2127; 0, N, iPr, CF3, H, CH2CHF2], [AA2128; 0, N, iPr, CF2H, H, CH2CHF2], [AA2129; 0, N, iPr, C2F5, H, CH2CHF2], [AA2130; 0, N, iPr, C3F7, H, CH2CHF2], [AA2131; 0, N, iPr, CH2CF3, H, CH2CHF2], [AA2132; 0, N, iPr, CH2CHF2, H, CH2CHF2], [AA2133; 1, N, iPr, H, H, CH2CHF2], [AA2134; 1, N, iPr, F, H, CH2CHF2], [AA2135; 1, N, iPr, Cl, H, CH2CHF2], [AA2136; 1, N, iPr, Br, H, CH2CHF2], [AA2137; 1, N, iPr, I, H, CH2CHF2], [AA2138; 1, N, iPr, CF3, H, CH2CHF2], [AA2139; 1, N, iPr, CF2H, H, CH2CHF2], [AA2140; 1, N, iPr, C2F5, H, CH2CHF2], [AA2141; 1, N, iPr, C3F7, H, CH2CHF2], [AA2142; 1, N, iPr, CH2CF3, H, CH2CHF2], [AA2143; 1, N, iPr, CH2CHF2, H, CH2CHF2], [AA2144; 2, N, iPr, H, H, CH2CHF2], [AA2145; 2, N, iPr, F, H, CH2CHF2], [AA2146; 2, N, iPr, Cl, H, CH2CHF2], [AA2147; 2, N, iPr, Br, H, CH2CHF2], [AA2148; 2, N, iPr, I, H, CH2CHF2], [AA2149; 2, N, iPr, CF3, H, CH2CHF2], [AA2150;[2,N,iPr,CF2H,H,CH2CHF2], [AA2151; 2,N,iPr,C2F5,H,CH2CHF2], [AA2152; 2,N,iPr,C3F7,H,CH2CHF2], [AA2153; 2,N,iPr,CH2CF3,H,CH2CHF2], [AA2154; 2,N,iPr,CH2CHF2,H,CH2CHF2], [AA2155; 0,CH,cPr,H,H,CH2CHF2], [AA2156; 0,CH,cPr,F,H,CH2CHF2], [AA2157; 0,CH,cPr,Cl,H,CH2CHF2], [AA2158; 0,CH,cPr,Br,H,CH2CHF2], [AA2159; 0,CH,cPr,I,H,CH2CHF2], [AA2160; 0,CH,cPr,CF3,H,CH2CHF2], [AA2161; 0,CH,cPr,CF2H,H,CH2CHF2], [AA2162; 0,CH,cPr,C2F5,H,CH2CHF2], [AA2163; 0,CH,cPr,C3F7,H,CH2CHF2], [AA2164; 0,CH,cPr,CH2CF3,H,CH2CHF2], [AA2165; 0,CH,cPr,CH2CHF2,H,CH2CHF2], [AA2166; 1,CH,cPr,H,H,CH2CHF2], [AA2167; 1,CH,cPr,F,H,CH2CHF2], [AA2168; 1,CH,cPr,Cl,H,CH2CHF2], [AA2169; 1,CH,cPr,Br,H,CH2CHF2], [AA2170; 1,CH,cPr,I,H,CH2CHF2], [AA2171; 1,CH,cPr,CF3,H,CH2CHF2], [AA2172; 1,CH,cPr,CF2H,H,CH2CHF2], [AA2173; 1,CH,cPr,C2F5,H,CH2CHF2], [AA2174; 1,CH,cPr,C3F7,H,CH2CHF2], [AA2175; 1,CH,cPr,CH2CF3,H,CH2CHF2], [AA2176; 1,CH,cPr,CH2CHF2,H,CH2CHF2], [AA2177; 2,CH,cPr,H,H,CH2CHF2], [AA2178; 2,CH,cPr,F,H,CH2CHF2], [AA2179; 2,CH,cPr,Cl,H,CH2CHF2], [AA2180; 2,CH,cPr,Br,H,CH2CHF2], [AA2181;[2, CH, cPr, I, H, CH2CHF2], [AA2182; 2, CH, cPr, CF3, H, CH2CHF2], [AA2183; 2, CH, cPr, CF2H, H, CH2CHF2], [AA2184; 2, CH, cPr, C2F5, H, CH2CHF2], [AA2185; 2, CH, cPr, C3F7, H, CH2CHF2], [AA2186; 2, CH, cPr, CH2CF3, H, CH2CHF2], [AA2187; 2, CH, cPr, CH2CHF2, H, CH2CHF2], [AA2188; 0, N, cPr, H, H, CH2CHF2], [AA2189; 0, N, cPr, F, H, CH2CHF2], [AA2190; 0, N, cPr, Cl, H, CH2CHF2], [AA2191; 0, N, cPr, Br, H, CH2CHF2], [AA2192; 0, N, cPr, I, H, CH2CHF2], [AA2193; 0, N, cPr, CF3, H, CH2CHF2], [AA2194; 0, N, cPr, CF2H, H, CH2CHF2], [AA2195; 0, N, cPr, C2F5, H, CH2CHF2], [AA2196; 0, N, cPr, C3F7, H, CH2CHF2], [AA2197; 0, N, cPr, CH2CF3, H, CH2CHF2], [AA2198; 0, N, cPr, CH2CHF2, H, CH2CHF2], [AA2199; 1, N, cPr, H, H, CH2CHF2], [AA2200; 1, N, cPr, F, H, CH2CHF2], [AA2201; 1, N, cPr, Cl, H, CH2CHF2], [AA2202; 1, N, cPr, Br, H, CH2CHF2], [AA2203; 1, N, cPr, I, H, CH2CHF2], [AA2204; 1, N, cPr, CF3, H, CH2CHF2], [AA2205; 1, N, cPr, CF2H, H, CH2CHF2], [AA2206; 1, N, cPr, C2F5, H, CH2CHF2], [AA2207; 1, N, cPr, C3F7, H, CH2CHF2], [AA2208; 1, N, cPr, CH2CF3, H, CH2CHF2], [AA2209; 1, N, cPr, CH2CHF2, H, CH2CHF2], [AA2210; 2, N, cPr, H, H, CH2CHF2], [AA2211; 2, N, cPr, F, H, CH2CHF2], [AA2212;[2,N,cPr,Cl,H,CH2CHF2], [AA2213; 2,N,cPr,Br,H,CH2CHF2], [AA2214; 2,N,cPr,I,H,CH2CHF2], [AA2215; 2,N,cPr,CF3,H,CH2CHF2], [AA2216; 2,N,cPr,CF2H,H,CH2CHF2], [AA2217; 2,N,cPr,C2F5,H,CH2CHF2], [AA2218; 2,N,cPr,C3F7,H,CH2CHF2], [AA2219; 2,N,cPr,CH2CF3,H,CH2CHF2], [AA2220; 2,N,cPr,CH2CHF2,H,CH2CHF2], [AA2221; 0,CH,H,H,F,CH2CHF2], [AA2222; 0,CH,H,H,Cl,CH2CHF2], [AA2223; 0,CH,H,H,Br,CH2CHF2], [AA2224; 0,CH,H,H,I,CH2CHF2], [AA2225; 0,CH,H,H,CF3,CH2CHF2], [AA2226; 0,CH,H,H,CF2H,CH2CHF2], [AA2227; 0,CH,H,H,C2F5,CH2CHF2], [AA2228; 0,CH,H,H,C3F7,CH2CHF2], [AA2229; 0,CH,H,H,CH2CF3,CH2CHF2], [AA2230; 0,CH,H,H,CH2CHF2,CH2CHF2], [AA2231; 1,CH,H,H,F,CH2CHF2], [AA2232; 1,CH,H,H,Cl,CH2CHF2], [AA2233; 1,CH,H,H,Br,CH2CHF2], [AA2234; 1,CH,H,H,I,CH2CHF2], [AA2235; 1,CH,H,H,CF3,CH2CHF2], [AA2236; 1,CH,H,H,CF2H,CH2CHF2], [AA2237; 1,CH,H,H,C2F5,CH2CHF2], [AA2238; 1,CH,H,H,C3F7,CH2CHF2], [AA2239; 1,CH,H,H,CH2CF3,CH2CHF2], [AA2240; 1,CH,H,H,CH2CHF2,CH2CHF2], [AA2241; 2,CH,H,H,F,CH2CHF2], [AA2242; 2,CH,H,H,Cl,CH2CHF2], [AA2243; 2,CH,H,H,Br,CH2CHF2], [AA2244;[2, CH, H, H, I, CH2CHF2], [AA2245; 2, CH, H, H, CF3, CH2CHF2], [AA2246; 2, CH, H, H, CF2H, CH2CHF2], [AA2247; 2, CH, H, H, C2F5, CH2CHF2], [AA2248; 2, CH, H, H, C3F7, CH2CHF2], [AA2249; 2, CH, H, H, CH2CF3, CH2CHF2], [AA2250; 2, CH, H, H, CH2CHF2, CH2CHF2], [AA2251; 0, N, H, H, F, CH2CHF2], [AA2252; 0, N, H, H, Cl, CH2CHF2], [AA2253; 0, N, H, H, Br, CH2CHF2], [AA2254; 0, N, H, H, I, CH2CHF2], [AA2255; 0, N, H, H, CF3, CH2CHF2], [AA2256; 0, N, H, H, CF2H, CH2CHF2], [AA2257; 0, N, H, H, C2F5, CH2CHF2], [AA2258; 0, N, H, H, C3F7, CH2CHF2], [AA2259; 0, N, H, H, CH2CF3, CH2CHF2], [AA2260; 0, N, H, H, CH2CHF2, CH2CHF2], [AA2261; 1, N, H, H, F, CH2CHF2], [AA2262; 1, N, H, H, Cl, CH2CHF2], [AA2263; 1, N, H, H, Br, CH2CHF2], [AA2264; 1, N, H, H, I, CH2CHF2], [AA2265; 1, N, H, H, CF3, CH2CHF2], [AA2266; 1, N, H, H, CF2H, CH2CHF2], [AA2267; 1, N, H, H, C2F5, CH2CHF2], [AA2268; 1, N, H, H, C3F7, CH2CHF2], [AA2269; 1, N, H, H, CH2CF3, CH2CHF2], [AA2270; 1, N, H, H, CH2CHF2, CH2CHF2], [AA2271; 2, N, H, H, F, CH2CHF2], [AA2272; 2, N, H, H, Cl, CH2CHF2], [AA2273; 2, N, H, H, Br, CH2CHF2], [AA2274; 2, N, H, H, I, CH2CHF2], [AA2275; 2, N, H, H, CF3, CH2CHF2], [AA2276; 2, N, H, H, CF2H, CH2CHF2], [AA2277;[2,N,H,H,C2F5,CH2CHF2], [AA2278; 2,N,H,H,C3F7,CH2CHF2], [AA2279; 2,N,H,H,CH2CF3,CH2CHF2], [AA2280; 2,N,H,H,CH2CHF2,CH2CHF2], [AA2281; 0,CH,Me,H,F,CH2CHF2], [AA2282; 0,CH,Me,H,Cl,CH2CHF2], [AA2283; 0,CH,Me,H,Br,CH2CHF2], [AA2284; 0,CH,Me,H,I,CH2CHF2], [AA2285; 0,CH,Me,H,CF3,CH2CHF2], [AA2286; 0,CH,Me,H,CF2H,CH2CHF2], [AA2287; 0,CH,Me,H,C2F5,CH2CHF2], [AA2288; 0,CH,Me,H,C3F7,CH2CHF2], [AA2289; 0,CH,Me,H,CH2CF3,CH2CHF2], [AA2290; 0,CH,Me,H,CH2CHF2,CH2CHF2], [AA2291; 1,CH,Me,H,F,CH2CHF2], [AA2292; 1,CH,Me,H,Cl,CH2CHF2], [AA2293; 1,CH,Me,H,Br,CH2CHF2], [AA2294; 1,CH,Me,H,I,CH2CHF2], [AA2295; 1,CH,Me,H,CF3,CH2CHF2], [AA2296; 1,CH,Me,H,CF2H,CH2CHF2], [AA2297; 1,CH,Me,H,C2F5,CH2CHF2], [AA2298; 1,CH,Me,H,C3F7,CH2CHF2], [AA2299; 1,CH,Me,H,CH2CF3,CH2CHF2], [AA2300; 1,CH,Me,H,CH2CHF2,CH2CHF2], [AA2301; 2,CH,Me,H,F,CH2CHF2], [AA2302; 2,CH,Me,H,Cl,CH2CHF2], [AA2303; 2,CH,Me,H,Br,CH2CHF2], [AA2304; 2,CH,Me,H,I,CH2CHF2], [AA2305; 2,CH,Me,H,CF3,CH2CHF2], [AA2306; 2,CH,Me,H,CF2H,CH2CHF2], [AA2307; 2,CH,Me,H,C2F5,CH2CHF2], [AA2308; 2,CH,Me,H,C3F7,CH2CHF2], [AA2309;[2, CH, Me, H, CH2CF3, CH2CHF2], [AA2310; 2, CH, Me, H, CH2CHF2, CH2CHF2], [AA2311; 0, N, Me, H, F, CH2CHF2], [AA2312; 0, N, Me, H, Cl, CH2CHF2], [AA2313; 0, N, Me, H, Br, CH2CHF2], [AA2314; 0, N, Me, H, I, CH2CHF2], [AA2315; 0, N, Me, H, CF3, CH2CHF2], [AA2316; 0, N, Me, H, CF2H, CH2CHF2], [AA2317; 0, N, Me, H, C2F5, CH2CHF2], [AA2318; 0, N, Me, H, C3F7, CH2CHF2], [AA2319; 0, N, Me, H, CH2CF3, CH2CHF2], [AA2320; 0, N, Me, H, CH2CHF2, CH2CHF2], [AA2321; 1, N, Me, H, F, CH2CHF2], [AA2322; 1, N, Me, H, Cl, CH2CHF2], [AA2323; 1, N, Me, H, Br, CH2CHF2], [AA2324; 1, N, Me, H, I, CH2CHF2], [AA2325; 1, N, Me, H, CF3, CH2CHF2], [AA2326; 1, N, Me, H, CF2H, CH2CHF2], [AA2327; 1, N, Me, H, C2F5, CH2CHF2], [AA2328; 1, N, Me, H, C3F7, CH2CHF2], [AA2329; 1, N, Me, H, CH2CF3, CH2CHF2], [AA2330; 1, N, Me, H, CH2CHF2, CH2CHF2], [AA2331; 2, N, Me, H, F, CH2CHF2], [AA2332; 2, N, Me, H, Cl, CH2CHF2], [AA2333; 2, N, Me, H, Br, CH2CHF2], [AA2334; 2, N, Me, H, I, CH2CHF2], [AA2335; 2, N, Me, H, CF3, CH2CHF2], [AA2336; 2, N, Me, H, CF2H, CH2CHF2], [AA2337; 2, N, Me, H, C2F5, CH2CHF2], [AA2338; 2, N, Me, H, C3F7, CH2CHF2], [AA2339; 2, N, Me, H, CH2CF3, CH2CHF2], [AA2340; 2, N, Me, H, CH2CHF2, CH2CHF2], [AA2341;[AA2342; 0, CH, Et, H, F, CH2CHF2], [AA2343; 0, CH, Et, H, Cl, CH2CHF2], [AA2344; 0, CH, Et, H, Br, CH2CHF2], [AA2345; 0, CH, Et, H, I, CH2CHF2], [AA2346; 0, CH, Et, H, CF3, CH2CHF2], [AA2347; 0, CH, Et, H, CF2H, CH2CHF2], [AA2348; 0, CH, Et, H, C2F5, CH2CHF2], [AA2349; 0, CH, Et, H, C3F7, CH2CHF2], [AA2350; 0, CH, Et, H, CH2CF3, CH2CHF2], [AA2351; 0, CH, Et, H, CH2CHF2, CH2CHF2], [AA2352; 1, CH, Et, H, F, CH2CHF2], [AA2353; 1, CH, Et, H, Cl, CH2CHF2], [AA2354; 1, CH, Et, H, Br, CH2CHF2], [AA2355; 1, CH, Et, H, I, CH2CHF2], [AA2356; 1, CH, Et, H, CF3, CH2CHF2], [AA2357; 1, CH, Et, H, CF2H, CH2CHF2], [AA2358; 1, CH, Et, H, C2F5, CH2CHF2], [AA2359; 1, CH, Et, H, C3F7, CH2CHF2], [AA2360; 1, CH, Et, H, CH2CF3, CH2CHF2], [AA2361; 1, CH, Et, H, CH2CHF2, CH2CHF2], [AA2362; 2, CH, Et, H, F, CH2CHF2], [AA2363; 2, CH, Et, H, Cl, CH2CHF2], [AA2364; 2, CH, Et, H, Br, CH2CHF2], [AA2365; 2, CH, Et, H, I, CH2CHF2], [AA2366; 2, CH, Et, H, CF3, CH2CHF2], [AA2367; 2, CH, Et, H, CF2H, CH2CHF2], [AA2368; 2, CH, Et, H, C2F5, CH2CHF2], [AA2369; 2, CH, Et, H, C3F7, CH2CHF2], [AA2370; 2, CH, Et, H, CH2CF3, CH2CHF2], [AA2371; 0, N, Et, H, F, CH2CHF2], [AA2372; 0, N, Et, H, Cl, CH2CHF2], [AA2373;[0, N, Et, H, Br, CH2CHF2], [AA2374; 0, N, Et, H, I, CH2CHF2], [AA2375; 0, N, Et, H, CF3, CH2CHF2], [AA2376; 0, N, Et, H, CF2H, CH2CHF2], [AA2377; 0, N, Et, H, C2F5, CH2CHF2], [AA2378; 0, N, Et, H, C3F7, CH2CHF2], [AA2379; 0, N, Et, H, CH2CF3, CH2CHF2], [AA2380; 0, N, Et, H, CH2CHF2, CH2CHF2], [AA2381; 1, N, Et, H, F, CH2CHF2], [AA2382; 1, N, Et, H, Cl, CH2CHF2], [AA2383; 1, N, Et, H, Br, CH2CHF2], [AA2384; 1, N, Et, H, I, CH2CHF2], [AA2385; 1, N, Et, H, CF3, CH2CHF2], [AA2386; 1, N, Et, H, CF2H, CH2CHF2], [AA2387; 1, N, Et, H, C2F5, CH2CHF2], [AA2388; 1, N, Et, H, C3F7, CH2CHF2], [AA2389; 1, N, Et, H, CH2CF3, CH2CHF2], [AA2390; 1, N, Et, H, CH2CHF2, CH2CHF2], [AA2391; 2, N, Et, H, F, CH2CHF2], [AA2392; 2, N, Et, H, Cl, CH2CHF2], [AA2393; 2, N, Et, H, Br, CH2CHF2], [AA2394; 2, N, Et, H, I, CH2CHF2], [AA2395; 2, N, Et, H, CF3, CH2CHF2], [AA2396; 2, N, Et, H, CF2H, CH2CHF2], [AA2397; 2, N, Et, H, C2F5, CH2CHF2], [AA2398; 2, N, Et, H, C3F7, CH2CHF2], [AA2399; 2, N, Et, H, CH2CF3, CH2CHF2], [AA2400; 2, N, Et, H, CH2CHF2, CH2CHF2], [AA2401; 0, CH, iPr, H, F, CH2CHF2], [AA2402; 0, CH, iPr, H, Cl, CH2CHF2], [AA2403; 0, CH, iPr, H, Br, CH2CHF2], [AA2404; 0, CH, iPr, H, I, CH2CHF2], [AA2405;[0, CH, iPr, H, CF3, CH2CHF2], [AA2406; 0, CH, iPr, H, CF2H, CH2CHF2], [AA2407; 0, CH, iPr, H, C2F5, CH2CHF2], [AA2408; 0, CH, iPr, H, C3F7, CH2CHF2], [AA2409; 0, CH, iPr, H, CH2CF3, CH2CHF2], [AA2410; 0, CH, iPr, H, CH2CHF2, CH2CHF2], [AA2411; 1, CH, iPr, H, F, CH2CHF2], [AA2412; 1, CH, iPr, H, Cl, CH2CHF2], [AA2413; 1, CH, iPr, H, Br, CH2CHF2], [AA2414; 1, CH, iPr, H, I, CH2CHF2], [AA2415; 1, CH, iPr, H, CF3, CH2CHF2], [AA2416; 1, CH, iPr, H, CF2H, CH2CHF2], [AA2417; 1, CH, iPr, H, C2F5, CH2CHF2], [AA2418; 1, CH, iPr, H, C3F7, CH2CHF2], [AA2419; 1, CH, iPr, H, CH2CF3, CH2CHF2], [AA2420; 1, CH, iPr, H, CH2CHF2, CH2CHF2], [AA2421; 2, CH, iPr, H, F, CH2CHF2], [AA2422; 2, CH, iPr, H, Cl, CH2CHF2], [AA2423; 2, CH, iPr, H, Br, CH2CHF2], [AA2424; 2, CH, iPr, H, I, CH2CHF2], [AA2425; 2, CH, iPr, H, CF3, CH2CHF2], [AA2426; 2, CH, iPr, H, CF2H, CH2CHF2], [AA2427; 2, CH, iPr, H, C2F5, CH2CHF2], [AA2428; 2, CH, iPr, H, C3F7, CH2CHF2], [AA2429; 2, CH, iPr, H, CH2CF3, CH2CHF2], [AA2430; 2, CH, iPr, H, CH2CHF2, CH2CHF2], [AA2431; 0, N, iPr, H, F, CH2CHF2], [AA2432; 0, N, iPr, H, Cl, CH2CHF2], [AA2433; 0, N, iPr, H, Br, CH2CHF2], [AA2434; 0, N, iPr, H, I, CH2CHF2], [AA2435; 0, N, iPr, H, CF3, CH2CHF2], [AA2436;[0, N, iPr, H, CF2H, CH2CHF2], [AA2437; 0, N, iPr, H, C2F5, CH2CHF2], [AA2438; 0, N, iPr, H, C3F7, CH2CHF2], [AA2439; 0, N, iPr, H, CH2CF3, CH2CHF2], [AA2440; 0, N, iPr, H, CH2CHF2, CH2CHF2], [AA2441; 1, N, iPr, H, F, CH2CHF2], [AA2442; 1, N, iPr, H, Cl, CH2CHF2], [AA2443; 1, N, iPr, H, Br, CH2CHF2], [AA2444; 1, N, iPr, H, I, CH2CHF2], [AA2445; 1, N, iPr, H, CF3, CH2CHF2], [AA2446; 1, N, iPr, H, CF2H, CH2CHF2], [AA2447; 1, N, iPr, H, C2F5, CH2CHF2], [AA2448; 1, N, iPr, H, C3F7, CH2CHF2], [AA2449; 1, N, iPr, H, CH2CF3, CH2CHF2], [AA2450; 1, N, iPr, H, CH2CHF2, CH2CHF2], [AA2451; 2, N, iPr, H, F, CH2CHF2], [AA2452; 2, N, iPr, H, Cl, CH2CHF2], [AA2453; 2, N, iPr, H, Br, CH2CHF2], [AA2454; 2, N, iPr, H, I, CH2CHF2], [AA2455; 2, N, iPr, H, CF3, CH2CHF2], [AA2456; 2, N, iPr, H, CF2H, CH2CHF2], [AA2457; 2, N, iPr, H, C2F5, CH2CHF2], [AA2458; 2, N, iPr, H, C3F7, CH2CHF2], [AA2459; 2, N, iPr, H, CH2CF3, CH2CHF2], [AA2460; 2, N, iPr, H, CH2CHF2, CH2CHF2], [AA2461; 0, CH, cPr, H, F, CH2CHF2], [AA2462; 0, CH, cPr, H, Cl, CH2CHF2], [AA2463; 0, CH, cPr, H, Br, CH2CHF2], [AA2464; 0, CH, cPr, H, I, CH2CHF2], [AA2465; 0, CH, cPr, H, CF3, CH2CHF2], [AA2466; 0, CH, cPr, H, CF2H, CH2CHF2], [AA2467;[0, CH, cPr, H, C2F5, CH2CHF2], [AA2468; 0, CH, cPr, H, C3F7, CH2CHF2], [AA2469; 0, CH, cPr, H, CH2CF3, CH2CHF2], [AA2470; 0, CH, cPr, H, CH2CHF2, CH2CHF2], [AA2471; 1, CH, cPr, H, F, CH2CHF2], [AA2472; 1, CH, cPr, H, Cl, CH2CHF2], [AA2473; 1, CH, cPr, H, Br, CH2CHF2], [AA2474; 1, CH, cPr, H, I, CH2CHF2], [AA2475; 1, CH, cPr, H, CF3, CH2CHF2], [AA2476; 1, CH, cPr, H, CF2H, CH2CHF2], [AA2477; 1, CH, cPr, H, C2F5, CH2CHF2], [AA2478; 1, CH, cPr, H, C3F7, CH2CHF2], [AA2479; 1, CH, cPr, H, CH2CF3, CH2CHF2], [AA2480; 1, CH, cPr, H, CH2CHF2, CH2CHF2], [AA2481; 2, CH, cPr, H, F, CH2CHF2], [AA2482; 2, CH, cPr, H, Cl, CH2CHF2], [AA2483; 2, CH, cPr, H, Br, CH2CHF2], [AA2484; 2, CH, cPr, H, I, CH2CHF2], [AA2485; 2, CH, cPr, H, CF3, CH2CHF2], [AA2486; 2, CH, cPr, H, CF2H, CH2CHF2], [AA2487; 2, CH, cPr, H, C2F5, CH2CHF2], [AA2488; 2, CH, cPr, H, C3F7, CH2CHF2], [AA2489; 2, CH, cPr, H, CH2CF3, CH2CHF2], [AA2490; 2, CH, cPr, H, CH2CHF2, CH2CHF2], [AA2491; 0, N, cPr, H, F, CH2CHF2], [AA2492; 0, N, cPr, H, Cl, CH2CHF2], [AA2493; 0, N, cPr, H, Br, CH2CHF2], [AA2494; 0, N, cPr, H, I, CH2CHF2], [AA2495; 0, N, cPr, H, CF3, CH2CHF2], [AA2496; 0, N, cPr, H, CF2H, CH2CHF2], [AA2497; 0, N, cPr, H, C2F5, CH2CHF2], [AA2498;[0, N, cPr, H, C3F7, CH2CHF2], [AA2499; 0, N, cPr, H, CH2CF3, CH2CHF2], [AA2500; 0, N, cPr, H, CH2CHF2, CH2CHF2], [AA2501; 1, N, cPr, H, F, CH2CHF2], [AA2502; 1, N, cPr, H, Cl, CH2CHF2], [AA2503; 1, N, cPr, H, Br, CH2CHF2], [AA2504; 1, N, cPr, H, I, CH2CHF2], [AA2505; 1, N, cPr, H, CF3, CH2CHF2], [AA2506; 1, N, cPr, H, CF2H, CH2CHF2], [AA2507; 1, N, cPr, H, C2F5, CH2CHF2], [AA2508; 1, N, cPr, H, C3F7, CH2CHF2], [AA2509; 1, N, cPr, H, CH2CF3, CH2CHF2], [AA2510; 1, N, cPr, H, CH2CHF2, CH2CHF2], [AA2511; 2, N, cPr, H, F, CH2CHF2], [AA2512; 2, N, cPr, H, Cl, CH2CHF2], [AA2513; 2, N, cPr, H, Br, CH2CHF2], [AA2514; 2, N, cPr, H, I, CH2CHF2], [AA2515; 2, N, cPr, H, CF3, CH2CHF2], [AA2516; 2, N, cPr, H, CF2H, CH2CHF2], [AA2517; 2, N, cPr, H, C2F5, CH2CHF2], [AA2518; 2, N, cPr, H, C3F7, CH2CHF2], [AA2519; 2, N, cPr, H, CH2CF3, CH2CHF2], [AA2520; 2, N, cPr, H, CH2CHF2, CH2CHF2], [AA2521; 0, CH, H, H, H, SCF3], [AA2522; 0, CH, H, F, H, SCF3], [AA2523; 0, CH, H, Cl, H, SCF3], [AA2524; 0, CH, H, Br, H, SCF3], [AA2525; 0, CH, H, I, H, SCF3], [AA2526; 0, CH, H, CF3, H, SCF3], [AA2527; 0, CH, H, CF2H, H, SCF3], [AA2528; 0, CH, H, C2F5, H, SCF3], [AA2529; 0, CH, H, C3F7, H, SCF3], [AA2530; 0, CH, H, CH2CF3, H, SCF3], [AA2531;[0, CH, H, CH2CHF2, H, SCF3], [AA2532; 1, CH, H, H, H, SCF3], [AA2533; 1, CH, H, F, H, SCF3], [AA2534; 1, CH, H, Cl, H, SCF3], [AA2535; 1, CH, H, Br, H, SCF3], [AA2536; 1, CH, H, I, H, SCF3], [AA2537; 1, CH, H, CF3, H, SCF3], [AA2538; 1, CH, H, CF2H, H, SCF3], [AA2539; 1, CH, H, C2F5, H, SCF3], [AA2540; 1, CH, H, C3F7, H, SCF3], [AA2541; 1, CH, H, CH2CF3, H, SCF3], [AA2542; 1, CH, H, CH2CHF2, H, SCF3], [AA2543; 2, CH, H, H, H, SCF3], [AA2544; 2, CH, H, F, H, SCF3], [AA2545; 2, CH, H, Cl, H, SCF3], [AA2546; 2, CH, H, Br, H, SCF3], [AA2547; 2, CH, H, I, H, SCF3], [AA2548; 2, CH, H, CF3, H, SCF3], [AA2549; 2, CH, H, CF2H, H, SCF3], [AA2550; 2, CH, H, C2F5, H, SCF3], [AA2551; 2, CH, H, C3F7, H, SCF3], [AA2552; 2, CH, H, CH2CF3, H, SCF3], [AA2553; 2, CH, H, CH2CHF2, H, SCF3], [AA2554; 0, N, H, H, H, SCF3], [AA2555; 0, N, H, F, H, SCF3], [AA2556; 0, N, H, Cl, H, SCF3], [AA2557; 0, N, H, Br, H, SCF3], [AA2558; 0, N, H, I, H, SCF3], [AA2559; 0, N, H, CF3, H, SCF3], [AA2560; 0, N, H, CF2H, H, SCF3], [AA2561; 0, N, H, C2F5, H, SCF3], [AA2562; 0, N, H, C3F7, H, SCF3], [AA2563; 0, N, H, CH2CF3, H, SCF3], [AA2564; 0, N, H, CH2CHF2, H, SCF3], [AA2565; 1, N, H, H, H, SCF3], [AA2566; 1, N, H, F, H, SCF3], [AA2567; 1, N, H, Cl, H, SCF3], [AA2568;[1, N, H, Br, H, SCF3], [AA2569; 1, N, H, I, H, SCF3], [AA2570; 1, N, H, CF3, H, SCF3], [AA2571; 1, N, H, CF2H, H, SCF3], [AA2572; 1, N, H, C2F5, H, SCF3], [AA2573; 1, N, H, C3F7, H, SCF3], [AA2574; 1, N, H, CH2CF3, H, SCF3], [AA2575; 1, N, H, CH2CHF2, H, SCF3], [AA2576; 2, N, H, H, H, SCF3], [AA2577; 2, N, H, F, H, SCF3], [AA2578; 2, N, H, Cl, H, SCF3], [AA2579; 2, N, H, Br, H, SCF3], [AA2580; 2, N, H, I, H, SCF3], [AA2581; 2, N, H, CF3, H, SCF3], [AA2582; 2, N, H, CF2H, H, SCF3], [AA2583; 2, N, H, C2F5, H, SCF3], [AA2584; 2, N, H, C3F7, H, SCF3], [AA2585; 2, N, H, CH2CF3, H, SCF3], [AA2586; 2, N, H, CH2CHF2, H, SCF3], [AA2587; 0, CH, Me, H, H, SCF3], [AA2588; 0, CH, Me, F, H, SCF3], [AA2589; 0, CH, Me, Cl, H, SCF3], [AA2590; 0, CH, Me, Br, H, SCF3], [AA2591; 0, CH, Me, I, H, SCF3], [AA2592; 0, CH, Me, CF3, H, SCF3], [AA2593; 0, CH, Me, CF2H, H, SCF3], [AA2594; 0, CH, Me, C2F5, H, SCF3], [AA2595; 0, CH, Me, C3F7, H, SCF3], [AA2596; 0, CH, Me, CH2CF3, H, SCF3], [AA2597; 0, CH, Me, CH2CHF2, H, SCF3], [AA2598; 1, CH, Me, H, H, SCF3], [AA2599; 1, CH, Me, F, H, SCF3], [AA2600; 1, CH, Me, Cl, H, SCF3], [AA2601; 1, CH, Me, Br, H, SCF3], [AA2602; 1, CH, Me, I, H, SCF3], [AA2603; 1, CH, Me, CF3, H, SCF3], [AA2604;[1, CH, Me, CF2H, H, SCF3], [AA2605; 1, CH, Me, C2F5, H, SCF3], [AA2606; 1, CH, Me, C3F7, H, SCF3], [AA2607; 1, CH, Me, CH2CF3, H, SCF3], [AA2608; 1, CH, Me, CH2CHF2, H, SCF3], [AA2609; 2, CH, Me, H, H, SCF3], [AA2610; 2, CH, Me, F, H, SCF3], [AA2611; 2, CH, Me, Cl, H, SCF3], [AA2612; 2, CH, Me, Br, H, SCF3], [AA2613; 2, CH, Me, I, H, SCF3], [AA2614; 2, CH, Me, CF3, H, SCF3], [AA2615; 2, CH, Me, CF2H, H, SCF3], [AA2616; 2, CH, Me, C2F5, H, SCF3], [AA2617; 2, CH, Me, C3F7, H, SCF3], [AA2618; 2, CH, Me, CH2CF3, H, SCF3], [AA2619; 2, CH, Me, CH2CHF2, H, SCF3], [AA2620; 0, N, Me, H, H, SCF3], [AA2621; 0, N, Me, F, H, SCF3], [AA2622; 0, N, Me, Cl, H, SCF3], [AA2623; 0, N, Me, Br, H, SCF3], [AA2624; 0, N, Me, I, H, SCF3], [AA2625; 0, N, Me, CF3, H, SCF3], [AA2626; 0, N, Me, CF2H, H, SCF3], [AA2627; 0, N, Me, C2F5, H, SCF3], [AA2628; 0, N, Me, C3F7, H, SCF3], [AA2629; 0, N, Me, CH2CF3, H, SCF3], [AA2630; 0, N, Me, CH2CHF2, H, SCF3], [AA2631; 1, N, Me, H, H, SCF3], [AA2632; 1, N, Me, F, H, SCF3], [AA2633; 1, N, Me, Cl, H, SCF3], [AA2634; 1, N, Me, Br, H, SCF3], [AA2635; 1, N, Me, I, H, SCF3], [AA2636; 1, N, Me, CF3, H, SCF3], [AA2637; 1, N, Me, CF2H, H, SCF3], [AA2638; 1, N, Me, C2F5, H, SCF3], [AA2639; 1, N, Me, C3F7, H, SCF3], [AA2640;[1,N,Me,CH2CF3,H,SCF3], [AA2641; 1,N,Me,CH2CHF2,H,SCF3], [AA2642; 2,N,Me,H,H,SCF3], [AA2643; 2,N,Me,F,H,SCF3], [AA2644; 2,N,Me,Cl,H,SCF3], [AA2645; 2,N,Me,Br,H,SCF3], [AA2646; 2,N,Me,I,H,SCF3], [AA2647; 2,N,Me,CF3,H,SCF3], [AA2648; 2,N,Me,CF2H,H,SCF3], [AA2649; 2,N,Me,C2F5,H,SCF3], [AA2650; 2,N,Me,C3F7,H,SCF3], [AA2651; 2,N,Me,CH2CF3,H,SCF3], [AA2652; 2,N,Me,CH2CHF2,H,SCF3], [AA2653; 0,CH,Et,H,H,SCF3], [AA2654; 0,CH,Et,F,H,SCF3], [AA2655; 0,CH,Et,Cl,H,SCF3], [AA2656; 0,CH,Et,Br,H,SCF3], [AA2657; 0,CH,Et,I,H,SCF3], [AA2658; 0,CH,Et,CF3,H,SCF3], [AA2659; 0,CH,Et,CF2H,H,SCF3], [AA2660; 0,CH,Et,C2F5,H,SCF3], [AA2661; 0,CH,Et,C3F7,H,SCF3], [AA2662; 0,CH,Et,CH2CF3,H,SCF3], [AA2663; 0,CH,Et,CH2CHF2,H,SCF3], [AA2664; 1,CH,Et,H,H,SCF3], [AA2665; 1,CH,Et,F,H,SCF3], [AA2666; 1,CH,Et,Cl,H,SCF3], [AA2667; 1,CH,Et,Br,H,SCF3], [AA2668; 1,CH,Et,I,H,SCF3], [AA2669; 1,CH,Et,CF3,H,SCF3], [AA2670; 1,CH,Et,CF2H,H,SCF3], [AA2671; 1,CH,Et,C2F5,H,SCF3], [AA2672; 1,CH,Et,C3F7,H,SCF3], [AA2673; 1,CH,Et,CH2CF3,H,SCF3], [AA2674; 1,CH,Et,CH2CHF2,H,SCF3], [AA2675;[2, CH, Et, H, H, SCF3], [AA2676; 2, CH, Et, F, H, SCF3], [AA2677; 2, CH, Et, Cl, H, SCF3], [AA2678; 2, CH, Et, Br, H, SCF3], [AA2679; 2, CH, Et, I, H, SCF3], [AA2680; 2, CH, Et, CF3, H, SCF3], [AA2681; 2, CH, Et, CF2H, H, SCF3], [AA2682; 2, CH, Et, C2F5, H, SCF3], [AA2683; 2, CH, Et, C3F7, H, SCF3], [AA2684; 2, CH, Et, CH2CF3, H, SCF3], [AA2685; 2, CH, Et, CH2CHF2, H, SCF3], [AA2686; 0, N, Et, H, H, SCF3], [AA2687; 0, N, Et, F, H, SCF3], [AA2688; 0, N, Et, Cl, H, SCF3], [AA2689; 0, N, Et, Br, H, SCF3], [AA2690; 0, N, Et, I, H, SCF3], [AA2691; 0, N, Et, CF3, H, SCF3], [AA2692; 0, N, Et, CF2H, H, SCF3], [AA2693; 0, N, Et, C2F5, H, SCF3], [AA2694; 0, N, Et, C3F7, H, SCF3], [AA2695; 0, N, Et, CH2CF3, H, SCF3], [AA2696; 0, N, Et, CH2CHF2, H, SCF3], [AA2697; 1, N, Et, H, H, SCF3], [AA2698; 1, N, Et, F, H, SCF3], [AA2699; 1, N, Et, Cl, H, SCF3], [AA2700; 1, N, Et, Br, H, SCF3];
[0606] [AA2701; 1, N, Et, I, H, SCF3], [AA2702; 1, N, Et, CF3, H, SCF3], [AA2703; 1, N, Et, CF2H, H, SCF3], [AA2704; 1, N, Et, C2F5, H, SCF3], [AA2705; 1, N, Et, C3F7, H, SCF3], [AA2706; 1, N, Et, CH2CF3, H, SCF3], [AA2707; 1, N, Et, CH2CHF2, H, SCF3], [AA2708; 2, N, Et, H, H, SCF3], [AA2709; 2, N, Et, F, H, SCF3], [AA2710; 2, N, Et, Cl, H, SCF3], [AA2711; 2, N, Et, Br, H, SCF3], [AA2712; 2, N, Et, I, H, SCF3], [AA2713; 2, N, Et, CF3, H, SCF3], [AA2714; 2, N, Et, CF2H, H, SCF3], [AA2715; 2, N, Et, C2F5, H, SCF3], [AA2716; 2, N, Et, C3F7, H, SCF3], [AA2717; 2, N, Et, CH2CF3, H, SCF3], [AA2718; 2, N, Et, CH2CHF2, H, SCF3], [AA2719; 0, CH, iPr, H, H, SCF3], [AA2720; 0, CH, iPr, F, H, SCF3], [AA2721; 0, CH, iPr, Cl, H, SCF3], [AA2722; 0, CH, iPr, Br, H, SCF3], [AA2723; 0, CH, iPr, I, H, SCF3], [AA2724; 0, CH, iPr, CF3, H, SCF3], [AA2725; 0, CH, iPr, CF2H, H, SCF3], [AA2726; 0, CH, iPr, C2F5, H, SCF3], [AA2727; 0, CH, iPr, C3F7, H, SCF3], [AA2728; 0, CH, iPr, CH2CF3, H, SCF3], [AA2729; 0, CH, iPr, CH2CHF2, H, SCF3], [AA2730; 1, CH, iPr, H, H, SCF3], [AA2731; 1, CH, iPr, F, H, SCF3], [AA2732; 1, CH, iPr, Cl, H, SCF3], [AA2733; 1, CH, iPr, Br, H, SCF3], [AA2734; 1, CH, iPr, I, H, SCF3], [AA2735; 1, CH, iPr, CF3, H, SCF3], [AA2736;[1, CH, iPr, CF2H, H, SCF3], [AA2737; 1, CH, iPr, C2F5, H, SCF3], [AA2738; 1, CH, iPr, C3F7, H, SCF3], [AA2739; 1, CH, iPr, CH2CF3, H, SCF3], [AA2740; 1, CH, iPr, CH2CHF2, H, SCF3], [AA2741; 2, CH, iPr, H, H, SCF3], [AA2742; 2, CH, iPr, F, H, SCF3], [AA2743; 2, CH, iPr, Cl, H, SCF3], [AA2744; 2, CH, iPr, Br, H, SCF3], [AA2745; 2, CH, iPr, I, H, SCF3], [AA2746; 2, CH, iPr, CF3, H, SCF3], [AA2747; 2, CH, iPr, CF2H, H, SCF3], [AA2748; 2, CH, iPr, C2F5, H, SCF3], [AA2749; 2, CH, iPr, C3F7, H, SCF3], [AA2750; 2, CH, iPr, CH2CF3, H, SCF3], [AA2751; 2, CH, iPr, CH2CHF2, H, SCF3], [AA2752; 0, N, iPr, H, H, SCF3], [AA2753; 0, N, iPr, F, H, SCF3], [AA2754; 0, N, iPr, Cl, H, SCF3], [AA2755; 0, N, iPr, Br, H, SCF3], [AA2756; 0, N, iPr, I, H, SCF3], [AA2757; 0, N, iPr, CF3, H, SCF3], [AA2758; 0, N, iPr, CF2H, H, SCF3], [AA2759; 0, N, iPr, C2F5, H, SCF3], [AA2760; 0, N, iPr, C3F7, H, SCF3], [AA2761; 0, N, iPr, CH2CF3, H, SCF3], [AA2762; 0, N, iPr, CH2CHF2, H, SCF3], [AA2763; 1, N, iPr, H, H, SCF3], [AA2764; 1, N, iPr, F, H, SCF3], [AA2765; 1, N, iPr, Cl, H, SCF3], [AA2766; 1, N, iPr, Br, H, SCF3], [AA2767; 1, N, iPr, I, H, SCF3], [AA2768; 1, N, iPr, CF3, H, SCF3], [AA2769; 1, N, iPr, CF2H, H, SCF3], [AA2770;[1,N,iPr,C2F5,H,SCF3], [AA2771; 1,N,iPr,C3F7,H,SCF3], [AA2772; 1,N,iPr,CH2CF3,H,SCF3], [AA2773; 1,N,iPr,CH2CHF2,H,SCF3], [AA2774; 2,N,iPr,H,H,SCF3], [AA2775; 2,N,iPr,F,H,SCF3], [AA2776; 2,N,iPr,Cl,H,SCF3], [AA2777; 2,N,iPr,Br,H,SCF3], [AA2778; 2,N,iPr,I,H,SCF3], [AA2779; 2,N,iPr,CF3,H,SCF3], [AA2780; 2,N,iPr,CF2H,H,SCF3], [AA2781; 2,N,iPr,C2F5,H,SCF3], [AA2782; 2,N,iPr,C3F7,H,SCF3], [AA2783; 2,N,iPr,CH2CF3,H,SCF3], [AA2784; 2,N,iPr,CH2CHF2,H,SCF3], [AA2785; 0,CH,cPr,H,H,SCF3], [AA2786; 0,CH,cPr,F,H,SCF3], [AA2787; 0,CH,cPr,Cl,H,SCF3], [AA2788; 0,CH,cPr,Br,H,SCF3], [AA2789; 0,CH,cPr,I,H,SCF3], [AA2790; 0,CH,cPr,CF3,H,SCF3], [AA2791; 0,CH,cPr,CF2H,H,SCF3], [AA2792; 0,CH,cPr,C2F5,H,SCF3], [AA2793; 0,CH,cPr,C3F7,H,SCF3], [AA2794; 0,CH,cPr,CH2CF3,H,SCF3], [AA2795; 0,CH,cPr,CH2CHF2,H,SCF3], [AA2796; 1,CH,cPr,H,H,SCF3], [AA2797; 1,CH,cPr,F,H,SCF3], [AA2798; 1,CH,cPr,Cl,H,SCF3], [AA2799; 1,CH,cPr,Br,H,SCF3], [AA2800; 1,CH,cPr,I,H,SCF3], [AA2801; 1,CH,cPr,CF3,H,SCF3], [AA2802; 1,CH,cPr,CF2H,H,SCF3], [AA2803; 1,CH,cPr,C2F5,H,SCF3], [AA2804;[1, CH, cPr, C3F7, H, SCF3], [AA2805; 1, CH, cPr, CH2CF3, H, SCF3], [AA2806; 1, CH, cPr, CH2CHF2, H, SCF3], [AA2807; 2, CH, cPr, H, H, SCF3], [AA2808; 2, CH, cPr, F, H, SCF3], [AA2809; 2, CH, cPr, Cl, H, SCF3], [AA2810; 2, CH, cPr, Br, H, SCF3], [AA2811; 2, CH, cPr, I, H, SCF3], [AA2812; 2, CH, cPr, CF3, H, SCF3], [AA2813; 2, CH, cPr, CF2H, H, SCF3], [AA2814; 2, CH, cPr, C2F5, H, SCF3], [AA2815; 2, CH, cPr, C3F7, H, SCF3], [AA2816; 2, CH, cPr, CH2CF3, H, SCF3], [AA2817; 2, CH, cPr, CH2CHF2, H, SCF3], [AA2818; 0, N, cPr, H, H, SCF3], [AA2819; 0, N, cPr, F, H, SCF3], [AA2820; 0, N, cPr, Cl, H, SCF3], [AA2821; 0, N, cPr, Br, H, SCF3], [AA2822; 0, N, cPr, I, H, SCF3], [AA2823; 0, N, cPr, CF3, H, SCF3], [AA2824; 0, N, cPr, CF2H, H, SCF3], [AA2825; 0, N, cPr, C2F5, H, SCF3], [AA2826; 0, N, cPr, C3F7, H, SCF3], [AA2827; 0, N, cPr, CH2CF3, H, SCF3], [AA2828; 0, N, cPr, CH2CHF2, H, SCF3], [AA2829; 1, N, cPr, H, H, SCF3], [AA2830; 1, N, cPr, F, H, SCF3], [AA2831; 1, N, cPr, Cl, H, SCF3], [AA2832; 1, N, cPr, Br, H, SCF3], [AA2833; 1, N, cPr, I, H, SCF3], [AA2834; 1, N, cPr, CF3, H, SCF3], [AA2835; 1, N, cPr, CF2H, H, SCF3], [AA2836; 1, N, cPr, C2F5, H, SCF3], [AA2837; 1, N, cPr, C3F7, H, SCF3], [AA2838;[1,N,cPr,CH2CF3,H,SCF3], [AA2839; 1,N,cPr,CH2CHF2,H,SCF3], [AA2840; 2,N,cPr,H,H,SCF3], [AA2841; 2,N,cPr,F,H,SCF3], [AA2842; 2,N,cPr,Cl,H,SCF3], [AA2843; 2,N,cPr,Br,H,SCF3], [AA2844; 2,N,cPr,I,H,SCF3], [AA2845; 2,N,cPr,CF3,H,SCF3], [AA2846; 2,N,cPr,CF2H,H,SCF3], [AA2847; 2,N,cPr,C2F5,H,SCF3], [AA2848; 2,N,cPr,C3F7,H,SCF3], [AA2849; 2,N,cPr,CH2CF3,H,SCF3], [AA2850; 2,N,cPr,CH2CHF2,H,SCF3], [AA2851; 0,CH,H,H,F,SCF3], [AA2852; 0,CH,H,H,Cl,SCF3], [AA2853; 0,CH,H,H,Br,SCF3], [AA2854; 0,CH,H,H,I,SCF3], [AA2855; 0,CH,H,H,CF3,SCF3], [AA2856; 0,CH,H,H,CF2H,SCF3], [AA2857; 0,CH,H,H,C2F5,SCF3], [AA2858; 0,CH,H,H,C3F7,SCF3], [AA2859; 0,CH,H,H,CH2CF3,SCF3], [AA2860; 0,CH,H,H,CH2CHF2,SCF3], [AA2861; 1,CH,H,H,F,SCF3], [AA2862; 1,CH,H,H,Cl,SCF3], [AA2863; 1,CH,H,H,Br,SCF3], [AA2864; 1,CH,H,H,I,SCF3], [AA2865; 1,CH,H,H,CF3,SCF3], [AA2866; 1,CH,H,H,CF2H,SCF3], [AA2867; 1,CH,H,H,C2F5,SCF3], [AA2868; 1,CH,H,H,C3F7,SCF3], [AA2869; 1,CH,H,H,CH2CF3,SCF3], [AA2870; 1,CH,H,H,CH2CHF2,SCF3], [AA2871; 2,CH,H,H,F,SCF3], [AA2872; 2,CH,H,H,Cl,SCF3], [AA2873; 2,CH,H,H,Br,SCF3], [AA2874;[2,CH,H,H,I,SCF3], [AA2875; 2,CH,H,H,CF3,SCF3], [AA2876; 2,CH,H,H,CF2H,SCF3], [AA2877; 2,CH,H,H,C2F5,SCF3], [AA2878; 2,CH,H,H,C3F7,SCF3], [AA2879; 2,CH,H,H,CH2CF3,SCF3], [AA2880; 2,CH,H,H,CH2CHF2,SCF3], [AA2881; 0,N,H,H,F,SCF3], [AA2882; 0,N,H,H,Cl,SCF3], [AA2883; 0,N,H,H,Br,SCF3], [AA2884; 0,N,H,H,I,SCF3], [AA2885; 0,N,H,H,CF3,SCF3], [AA2886; 0,N,H,H,CF2H,SCF3], [AA2887; 0,N,H,H,C2F5,SCF3], [AA2888; 0,N,H,H,C3F7,SCF3], [AA2889; 0,N,H,H,CH2CF3,SCF3], [AA2890; 0,N,H,H,CH2CHF2,SCF3], [AA2891; 1,N,H,H,F,SCF3], [AA2892; 1,N,H,H,Cl,SCF3], [AA2893; 1,N,H,H,Br,SCF3], [AA2894; 1,N,H,H,I,SCF3], [AA2895; 1,N,H,H,CF3,SCF3], [AA2896; 1,N,H,H,CF2H,SCF3], [AA2897; 1,N,H,H,C2F5,SCF3], [AA2898; 1,N,H,H,C3F7,SCF3], [AA2899; 1,N,H,H,CH2CF3,SCF3], [AA2900; 1,N,H,H,CH2CHF2,SCF3], [AA2901; 2,N,H,H,F,SCF3], [AA2902; 2,N,H,H,Cl,SCF3], [AA2903; 2,N,H,H,Br,SCF3], [AA2904; 2,N,H,H,I,SCF3], [AA2905; 2,N,H,H,CF3,SCF3], [AA2906; 2,N,H,H,CF2H,SCF3], [AA2907; 2,N,H,H,C2F5,SCF3], [AA2908; 2,N,H,H,C3F7,SCF3], [AA2909; 2,N,H,H,CH2CF3,SCF3], [AA2910; 2,N,H,H,CH2CHF2,SCF3], [AA2911;[0, CH, Me, H, F, SCF3], [AA2912; 0, CH, Me, H, Cl, SCF3], [AA2913; 0, CH, Me, H, Br, SCF3], [AA2914; 0, CH, Me, H, I, SCF3], [AA2915; 0, CH, Me, H, CF3, SCF3], [AA2916; 0, CH, Me, H, CF2H, SCF3], [AA2917; 0, CH, Me, H, C2F5, SCF3], [AA2918; 0, CH, Me, H, C3F7, SCF3], [AA2919; 0, CH, Me, H, CH2CF3, SCF3], [AA2920; 0, CH, Me, H, CH2CHF2, SCF3], [AA2921; 1, CH, Me, H, F, SCF3], [AA2922; 1, CH, Me, H, Cl, SCF3], [AA2923; 1, CH, Me, H, Br, SCF3], [AA2924; 1, CH, Me, H, I, SCF3], [AA2925; 1, CH, Me, H, CF3, SCF3], [AA2926; 1, CH, Me, H, CF2H, SCF3], [AA2927; 1, CH, Me, H, C2F5, SCF3], [AA2928; 1, CH, Me, H, C3F7, SCF3], [AA2929; 1, CH, Me, H, CH2CF3, SCF3], [AA2930; 1, CH, Me, H, CH2CHF2, SCF3], [AA2931; 2, CH, Me, H, F, SCF3], [AA2932; 2, CH, Me, H, Cl, SCF3], [AA2933; 2, CH, Me, H, Br, SCF3], [AA2934; 2, CH, Me, H, I, SCF3], [AA2935; 2, CH, Me, H, CF3, SCF3], [AA2936; 2, CH, Me, H, CF2H, SCF3], [AA2937; 2, CH, Me, H, C2F5, SCF3], [AA2938; 2, CH, Me, H, C3F7, SCF3], [AA2939; 2, CH, Me, H, CH2CF3, SCF3], [AA2940; 2, CH, Me, H, CH2CHF2, SCF3], [AA2941; 0, N, Me, H, F, SCF3], [AA2942; 0, N, Me, H, Cl, SCF3], [AA2943; 0, N, Me, H, Br, SCF3], [AA2944; 0, N, Me, H, I, SCF3], [AA2945; 0, N, Me, H, CF3, SCF3], [AA2946;[0, N, Me, H, CF2H, SCF3], [AA2947; 0, N, Me, H, C2F5, SCF3], [AA2948; 0, N, Me, H, C3F7, SCF3], [AA2949; 0, N, Me, H, CH2CF3, SCF3], [AA2950; 0, N, Me, H, CH2CHF2, SCF3], [AA2951; 1, N, Me, H, F, SCF3], [AA2952; 1, N, Me, H, Cl, SCF3], [AA2953; 1, N, Me, H, Br, SCF3], [AA2954; 1, N, Me, H, I, SCF3], [AA2955; 1, N, Me, H, CF3, SCF3], [AA2956; 1, N, Me, H, CF2H, SCF3], [AA2957; 1, N, Me, H, C2F5, SCF3], [AA2958; 1, N, Me, H, C3F7, SCF3], [AA2959; 1, N, Me, H, CH2CF3, SCF3], [AA2960; 1, N, Me, H, CH2CHF2, SCF3], [AA2961; 2, N, Me, H, F, SCF3], [AA2962; 2, N, Me, H, Cl, SCF3], [AA2963; 2, N, Me, H, Br, SCF3], [AA2964; 2, N, Me, H, I, SCF3], [AA2965; 2, N, Me, H, CF3, SCF3], [AA2966; 2, N, Me, H, CF2H, SCF3], [AA2967; 2, N, Me, H, C2F5, SCF3], [AA2968; 2, N, Me, H, C3F7, SCF3], [AA2969; 2, N, Me, H, CH2CF3, SCF3], [AA2970; 2, N, Me, H, CH2CHF2, SCF3], [AA2971; 0, CH, Et, H, F, SCF3], [AA2972; 0, CH, Et, H, Cl, SCF3], [AA2973; 0, CH, Et, H, Br, SCF3], [AA2974; 0, CH, Et, H, I, SCF3], [AA2975; 0, CH, Et, H, CF3, SCF3], [AA2976; 0, CH, Et, H, CF2H, SCF3], [AA2977; 0, CH, Et, H, C2F5, SCF3], [AA2978; 0, CH, Et, H, C3F7, SCF3], [AA2979; 0, CH, Et, H, CH2CF3, SCF3], [AA2980; 0, CH, Et, H, CH2CHF2, SCF3], [AA2981;[1, CH, Et, H, F, SCF3], [AA2982; 1, CH, Et, H, Cl, SCF3], [AA2983; 1, CH, Et, H, Br, SCF3], [AA2984; 1, CH, Et, H, I, SCF3], [AA2985; 1, CH, Et, H, CF3, SCF3], [AA2986; 1, CH, Et, H, CF2H, SCF3], [AA2987; 1, CH, Et, H, C2F5, SCF3], [AA2988; 1, CH, Et, H, C3F7, SCF3], [AA2989; 1, CH, Et, H, CH2CF3, SCF3], [AA2990; 1, CH, Et, H, CH2CHF2, SCF3], [AA2991; 2, CH, Et, H, F, SCF3], [AA2992; 2, CH, Et, H, Cl, SCF3], [AA2993; 2, CH, Et, H, Br, SCF3], [AA2994; 2, CH, Et, H, I, SCF3], [AA2995; 2, CH, Et, H, CF3, SCF3], [AA2996; 2, CH, Et, H, CF2H, SCF3], [AA2997; 2, CH, Et, H, C2F5, SCF3], [AA2998; 2, CH, Et, H, C3F7, SCF3], [AA2999; 2, CH, Et, H, CH2CF3, SCF3], [AA3000; 2, CH, Et, H, CH2CHF2, SCF3], [AA3001; 0, N, Et, H, F, SCF3], [AA3002; 0, N, Et, H, Cl, SCF3], [AA3003; 0, N, Et, H, Br, SCF3], [AA3004; 0, N, Et, H, I, SCF3], [AA3005; 0, N, Et, H, CF3, SCF3], [AA3006; 0, N, Et, H, CF2H, SCF3], [AA3007; 0, N, Et, H, C2F5, SCF3], [AA3008; 0, N, Et, H, C3F7, SCF3], [AA3009; 0, N, Et, H, CH2CF3, SCF3], [AA3010; 0, N, Et, H, CH2CHF2, SCF3], [AA3011; 1, N, Et, H, F, SCF3], [AA3012; 1, N, Et, H, Cl, SCF3], [AA3013; 1, N, Et, H, Br, SCF3], [AA3014; 1, N, Et, H, I, SCF3], [AA3015; 1, N, Et, H, CF3, SCF3], [AA3016; 1, N, Et, H, CF2H, SCF3], [AA3017;[1,N,Et,H,C2F5,SCF3], [AA3018; 1,N,Et,H,C3F7,SCF3], [AA3019; 1,N,Et,H,CH2CF3,SCF3], [AA3020; 1,N,Et,H,CH2CHF2,SCF3], [AA3021; 2,N,Et,H,F,SCF3], [AA3022; 2,N,Et,H,Cl,SCF3], [AA3023; 2,N,Et,H,Br,SCF3], [AA3024; 2,N,Et,H,I,SCF3], [AA3025; 2,N,Et,H,CF3,SCF3], [AA3026; 2,N,Et,H,CF2H,SCF3], [AA3027; 2,N,Et,H,C2F5,SCF3], [AA3028; 2,N,Et,H,C3F7,SCF3], [AA3029; 2,N,Et,H,CH2CF3,SCF3], [AA3030; 2,N,Et,H,CH2CHF2,SCF3], [AA3031; 0,CH,iPr,H,F,SCF3], [AA3032; 0,CH,iPr,H,Cl,SCF3], [AA3033; 0,CH,iPr,H,Br,SCF3], [AA3034; 0,CH,iPr,H,I,SCF3], [AA3035; 0,CH,iPr,H,CF3,SCF3], [AA3036; 0,CH,iPr,H,CF2H,SCF3], [AA3037; 0,CH,iPr,H,C2F5,SCF3], [AA3038; 0,CH,iPr,H,C3F7,SCF3], [AA3039; 0,CH,iPr,H,CH2CF3,SCF3], [AA3040; 0,CH,iPr,H,CH2CHF2,SCF3], [AA3041; 1,CH,iPr,H,F,SCF3], [AA3042; 1,CH,iPr,H,Cl,SCF3], [AA3043; 1,CH,iPr,H,Br,SCF3], [AA3044; 1,CH,iPr,H,I,SCF3], [AA3045; 1,CH,iPr,H,CF3,SCF3], [AA3046; 1,CH,iPr,H,CF2H,SCF3], [AA3047; 1,CH,iPr,H,C2F5,SCF3], [AA3048; 1,CH,iPr,H,C3F7,SCF3], [AA3049; 1,CH,iPr,H,CH2CF3,SCF3], [AA3050; 1,CH,iPr,H,CH2CHF2,SCF3], [AA3051;[2, CH, iPr, H, F, SCF3], [AA3052; 2, CH, iPr, H, Cl, SCF3], [AA3053; 2, CH, iPr, H, Br, SCF3], [AA3054; 2, CH, iPr, H, I, SCF3], [AA3055; 2, CH, iPr, H, CF3, SCF3], [AA3056; 2, CH, iPr, H, CF2H, SCF3], [AA3057; 2, CH, iPr, H, C2F5, SCF3], [AA3058; 2, CH, iPr, H, C3F7, SCF3], [AA3059; 2, CH, iPr, H, CH2CF3, SCF3], [AA3060; 2, CH, iPr, H, CH2CHF2, SCF3], [AA3061; 0, N, iPr, H, F, SCF3], [AA3062; 0, N, iPr, H, Cl, SCF3], [AA3063; 0, N, iPr, H, Br, SCF3], [AA3064; 0, N, iPr, H, I, SCF3], [AA3065; 0, N, iPr, H, CF3, SCF3], [AA3066; 0, N, iPr, H, CF2H, SCF3], [AA3067; 0, N, iPr, H, C2F5, SCF3], [AA3068; 0, N, iPr, H, C3F7, SCF3], [AA3069; 0, N, iPr, H, CH2CF3, SCF3], [AA3070; 0, N, iPr, H, CH2CHF2, SCF3], [AA3071; 1, N, iPr, H, F, SCF3], [AA3072; 1, N, iPr, H, Cl, SCF3], [AA3073; 1, N, iPr, H, Br, SCF3], [AA3074; 1, N, iPr, H, I, SCF3], [AA3075; 1, N, iPr, H, CF3, SCF3], [AA3076; 1, N, iPr, H, CF2H, SCF3], [AA3077; 1, N, iPr, H, C2F5, SCF3], [AA3078; 1, N, iPr, H, C3F7, SCF3], [AA3079; 1, N, iPr, H, CH2CF3, SCF3], [AA3080; 1, N, iPr, H, CH2CHF2, SCF3], [AA3081; 2, N, iPr, H, F, SCF3], [AA3082; 2, N, iPr, H, Cl, SCF3], [AA3083; 2, N, iPr, H, Br, SCF3], [AA3084; 2, N, iPr, H, I, SCF3], [AA3085; 2, N, iPr, H, CF3, SCF3], [AA3086;[2,N,iPr,H,CF2H,SCF3], [AA3087; 2,N,iPr,H,C2F5,SCF3], [AA3088; 2,N,iPr,H,C3F7,SCF3], [AA3089; 2,N,iPr,H,CH2CF3,SCF3], [AA3090; 2,N,iPr,H,CH2CHF2,SCF3], [AA3091; 0,CH,cPr,H,F,SCF3], [AA3092; 0,CH,cPr,H,Cl,SCF3], [AA3093; 0,CH,cPr,H,Br,SCF3], [AA3094; 0,CH,cPr,H,I,SCF3], [AA3095; 0,CH,cPr,H,CF3,SCF3], [AA3096; 0,CH,cPr,H,CF2H,SCF3], [AA3097; 0,CH,cPr,H,C2F5,SCF3], [AA3098; 0,CH,cPr,H,C3F7,SCF3], [AA3099; 0,CH,cPr,H,CH2CF3,SCF3], [AA3100; 0,CH,cPr,H,CH2CHF2,SCF3], [AA3101; 1,CH,cPr,H,F,SCF3], [AA3102; 1,CH,cPr,H,Cl,SCF3], [AA3103; 1,CH,cPr,H,Br,SCF3], [AA3104; 1,CH,cPr,H,I,SCF3], [AA3105; 1,CH,cPr,H,CF3,SCF3], [AA3106; 1,CH,cPr,H,CF2H,SCF3], [AA3107; 1,CH,cPr,H,C2F5,SCF3], [AA3108; 1,CH,cPr,H,C3F7,SCF3], [AA3109; 1,CH,cPr,H,CH2CF3,SCF3], [AA3110; 1,CH,cPr,H,CH2CHF2,SCF3], [AA3111; 2,CH,cPr,H,F,SCF3], [AA3112; 2,CH,cPr,H,Cl,SCF3], [AA3113; 2,CH,cPr,H,Br,SCF3], [AA3114; 2,CH,cPr,H,I,SCF3], [AA3115; 2,CH,cPr,H,CF3,SCF3], [AA3116; 2,CH,cPr,H,CF2H,SCF3], [AA3117; 2,CH,cPr,H,C2F5,SCF3], [AA3118; 2,CH,cPr,H,C3F7,SCF3], [AA3119; 2,CH,cPr,H,CH2CF3,SCF3], [AA3120;[2,CH,cPr,H,CH2CHF2,SCF3], [AA3121; 0,N,cPr,H,F,SCF3], [AA3122; 0,N,cPr,H,Cl,SCF3], [AA3123; 0,N,cPr,H,Br,SCF3], [AA3124; 0,N,cPr,H,I,SCF3], [AA3125; 0,N,cPr,H,CF3,SCF3], [AA3126; 0,N,cPr,H,CF2H,SCF3], [AA3127; 0,N,cPr,H,C2F5,SCF3], [AA3128; 0,N,cPr,H,C3F7,SCF3], [AA3129; 0,N,cPr,H,CH2CF3,SCF3], [AA3130; 0,N,cPr,H,CH2CHF2,SCF3], [AA3131; 1,N,cPr,H,F,SCF3], [AA3132; 1,N,cPr,H,Cl,SCF3], [AA3133; 1,N,cPr,H,Br,SCF3], [AA3134; 1,N,cPr,H,I,SCF3], [AA3135; 1,N,cPr,H,CF3,SCF3], [AA3136; 1,N,cPr,H,CF2H,SCF3], [AA3137; 1,N,cPr,H,C2F5,SCF3], [AA3138; 1,N,cPr,H,C3F7,SCF3], [AA3139; 1,N,cPr,H,CH2CF3,SCF3], [AA3140; 1,N,cPr,H,CH2CHF2,SCF3], [AA3141; 2,N,cPr,H,F,SCF3], [AA3142; 2,N,cPr,H,Cl,SCF3], [AA3143; 2,N,cPr,H,Br,SCF3], [AA3144; 2,N,cPr,H,I,SCF3], [AA3145; 2,N,cPr,H,CF3,SCF3], [AA3146; 2,N,cPr,H,CF2H,SCF3], [AA3147; 2,N,cPr,H,C2F5,SCF3], [AA3148; 2,N,cPr,H,C3F7,SCF3], [AA3149; 2,N,cPr,H,CH2CF3,SCF3], [AA3150; 2,N,cPr,H,CH2CHF2,SCF3], [AA3151; 0,CH,H,H,H,OCF3], [AA3152; 0,CH,H,F,H,OCF3], [AA3153; 0,CH,H,Cl,H,OCF3], [AA3154; 0,CH,H,Br,H,OCF3], [AA3155;[0, CH, H, I, H, OCF3], [AA3156; 0, CH, H, CF3, H, OCF3], [AA3157; 0, CH, H, CF2H, H, OCF3], [AA3158; 0, CH, H, C2F5, H, OCF3], [AA3159; 0, CH, H, C3F7, H, OCF3], [AA3160; 0, CH, H, CH2CF3, H, OCF3], [AA3161; 0, CH, H, CH2CHF2, H, OCF3], [AA3162; 1, CH, H, H, H, OCF3], [AA3163; 1, CH, H, F, H, OCF3], [AA3164; 1, CH, H, Cl, H, OCF3], [AA3165; 1, CH, H, Br, H, OCF3], [AA3166; 1, CH, H, I, H, OCF3], [AA3167; 1, CH, H, CF3, H, OCF3], [AA3168; 1, CH, H, CF2H, H, OCF3], [AA3169; 1, CH, H, C2F5, H, OCF3], [AA3170; 1, CH, H, C3F7, H, OCF3], [AA3171; 1, CH, H, CH2CF3, H, OCF3], [AA3172; 1, CH, H, CH2CHF2, H, OCF3], [AA3173; 2, CH, H, H, H, OCF3], [AA3174; 2, CH, H, F, H, OCF3], [AA3175; 2, CH, H, Cl, H, OCF3], [AA3176; 2, CH, H, Br, H, OCF3], [AA3177; 2, CH, H, I, H, OCF3], [AA3178; 2, CH, H, CF3, H, OCF3], [AA3179; 2, CH, H, CF2H, H, OCF3], [AA3180; 2, CH, H, C2F5, H, OCF3], [AA3181; 2, CH, H, C3F7, H, OCF3], [AA3182; 2, CH, H, CH2CF3, H, OCF3], [AA3183; 2, CH, H, CH2CHF2, H, OCF3], [AA3184; 0, N, H, H, H, OCF3], [AA3185; 0, N, H, F, H, OCF3], [AA3186; 0, N, H, Cl, H, OCF3], [AA3187; 0, N, H, Br, H, OCF3], [AA3188; 0, N, H, I, H, OCF3], [AA3189; 0, N, H, CF3, H, OCF3], [AA3190; 0, N, H, CF2H, H, OCF3], [AA3191; 0, N, H, C2F5, H, OCF3], [AA3192;[0, N, H, C3F7, H, OCF3], [AA3193; 0, N, H, CH2CF3, H, OCF3], [AA3194; 0, N, H, CH2CHF2, H, OCF3], [AA3195; 1, N, H, H, H, OCF3], [AA3196; 1, N, H, F, H, OCF3], [AA3197; 1, N, H, Cl, H, OCF3], [AA3198; 1, N, H, Br, H, OCF3], [AA3199; 1, N, H, I, H, OCF3], [AA3200; 1, N, H, CF3, H, OCF3], [AA3201; 1, N, H, CF2H, H, OCF3], [AA3202; 1, N, H, C2F5, H, OCF3], [AA3203; 1, N, H, C3F7, H, OCF3], [AA3204; 1, N, H, CH2CF3, H, OCF3], [AA3205; 1, N, H, CH2CHF2, H, OCF3], [AA3206; 2, N, H, H, H, OCF3], [AA3207; 2, N, H, F, H, OCF3], [AA3208; 2, N, H, Cl, H, OCF3], [AA3209; 2, N, H, Br, H, OCF3], [AA3210; 2, N, H, I, H, OCF3], [AA3211; 2, N, H, CF3, H, OCF3], [AA3212; 2, N, H, CF2H, H, OCF3], [AA3213; 2, N, H, C2F5, H, OCF3], [AA3214; 2, N, H, C3F7, H, OCF3], [AA3215; 2, N, H, CH2CF3, H, OCF3], [AA3216; 2, N, H, CH2CHF2, H, OCF3], [AA3217; 0, CH, Me, H, H, OCF3], [AA3218; 0, CH, Me, F, H, OCF3], [AA3219; 0, CH, Me, Cl, H, OCF3], [AA3220; 0, CH, Me, Br, H, OCF3], [AA3221; 0, CH, Me, I, H, OCF3], [AA3222; 0, CH, Me, CF3, H, OCF3], [AA3223; 0, CH, Me, CF2H, H, OCF3], [AA3224; 0, CH, Me, C2F5, H, OCF3], [AA3225; 0, CH, Me, C3F7, H, OCF3], [AA3226; 0, CH, Me, CH2CF3, H, OCF3], [AA3227; 0, CH, Me, CH2CHF2, H, OCF3], [AA3228; 1, CH, Me, H, H, OCF3], [AA3229;[1, CH, Me, F, H, OCF3], [AA3230; 1, CH, Me, Cl, H, OCF3], [AA3231; 1, CH, Me, Br, H, OCF3], [AA3232; 1, CH, Me, I, H, OCF3], [AA3233; 1, CH, Me, CF3, H, OCF3], [AA3234; 1, CH, Me, CF2H, H, OCF3], [AA3235; 1, CH, Me, C2F5, H, OCF3], [AA3236; 1, CH, Me, C3F7, H, OCF3], [AA3237; 1, CH, Me, CH2CF3, H, OCF3], [AA3238; 1, CH, Me, CH2CHF2, H, OCF3], [AA3239; 2, CH, Me, H, H, OCF3], [AA3240; 2, CH, Me, F, H, OCF3], [AA3241; 2, CH, Me, Cl, H, OCF3], [AA3242; 2, CH, Me, Br, H, OCF3], [AA3243; 2, CH, Me, I, H, OCF3], [AA3244; 2, CH, Me, CF3, H, OCF3], [AA3245; 2, CH, Me, CF2H, H, OCF3], [AA3246; 2, CH, Me, C2F5, H, OCF3], [AA3247; 2, CH, Me, C3F7, H, OCF3], [AA3248; 2, CH, Me, CH2CF3, H, OCF3], [AA3249; 2, CH, Me, CH2CHF2, H, OCF3], [AA3250; 0, N, Me, H, H, OCF3], [AA3251; 0, N, Me, F, H, OCF3], [AA3252; 0, N, Me, Cl, H, OCF3], [AA3253; 0, N, Me, Br, H, OCF3], [AA3254; 0, N, Me, I, H, OCF3], [AA3255; 0, N, Me, CF3, H, OCF3], [AA3256; 0, N, Me, CF2H, H, OCF3], [AA3257; 0, N, Me, C2F5, H, OCF3], [AA3258; 0, N, Me, C3F7, H, OCF3], [AA3259; 0, N, Me, CH2CF3, H, OCF3], [AA3260; 0, N, Me, CH2CHF2, H, OCF3], [AA3261; 1, N, Me, H, H, OCF3], [AA3262; 1, N, Me, F, H, OCF3], [AA3263; 1, N, Me, Cl, H, OCF3], [AA3264; 1, N, Me, Br, H, OCF3], [AA3265;[1,N,Me,I,H,OCF3], [AA3266; 1,N,Me,CF3,H,OCF3], [AA3267; 1,N,Me,CF2H,H,OCF3], [AA3268; 1,N,Me,C2F5,H,OCF3], [AA3269; 1,N,Me,C3F7,H,OCF3], [AA3270; 1,N,Me,CH2CF3,H,OCF3], [AA3271; 1,N,Me,CH2CHF2,H,OCF3], [AA3272; 2,N,Me,H,H,OCF3], [AA3273; 2,N,Me,F,H,OCF3], [AA3274; 2,N,Me,Cl,H,OCF3], [AA3275; 2,N,Me,Br,H,OCF3], [AA3276; 2,N,Me,I,H,OCF3], [AA3277; 2,N,Me,CF3,H,OCF3], [AA3278; 2,N,Me,CF2H,H,OCF3], [AA3279; 2,N,Me,C2F5,H,OCF3], [AA3280; 2,N,Me,C3F7,H,OCF3], [AA3281; 2,N,Me,CH2CF3,H,OCF3], [AA3282; 2,N,Me,CH2CHF2,H,OCF3], [AA3283; 0,CH,Et,H,H,OCF3], [AA3284; 0,CH,Et,F,H,OCF3], [AA3285; 0,CH,Et,Cl,H,OCF3], [AA3286; 0,CH,Et,Br,H,OCF3], [AA3287; 0,CH,Et,I,H,OCF3], [AA3288; 0,CH,Et,CF3,H,OCF3], [AA3289; 0,CH,Et,CF2H,H,OCF3], [AA3290; 0,CH,Et,C2F5,H,OCF3], [AA3291; 0,CH,Et,C3F7,H,OCF3], [AA3292; 0,CH,Et,CH2CF3,H,OCF3], [AA3293; 0,CH,Et,CH2CHF2,H,OCF3], [AA3294; 1,CH,Et,H,H,OCF3], [AA3295; 1,CH,Et,F,H,OCF3], [AA3296; 1,CH,Et,Cl,H,OCF3], [AA3297; 1,CH,Et,Br,H,OCF3], [AA3298; 1,CH,Et,I,H,OCF3], [AA3299; 1,CH,Et,CF3,H,OCF3], [AA3300; 1,CH,Et,CF2H,H,OCF3], [AA3301;[1, CH, Et, C2F5, H, OCF3], [AA3302; 1, CH, Et, C3F7, H, OCF3], [AA3303; 1, CH, Et, CH2CF3, H, OCF3], [AA3304; 1, CH, Et, CH2CHF2, H, OCF3], [AA3305; 2, CH, Et, H, H, OCF3], [AA3306; 2, CH, Et, F, H, OCF3], [AA3307; 2, CH, Et, Cl, H, OCF3], [AA3308; 2, CH, Et, Br, H, OCF3], [AA3309; 2, CH, Et, I, H, OCF3], [AA3310; 2, CH, Et, CF3, H, OCF3], [AA3311; 2, CH, Et, CF2H, H, OCF3], [AA3312; 2, CH, Et, C2F5, H, OCF3], [AA3313; 2, CH, Et, C3F7, H, OCF3], [AA3314; 2, CH, Et, CH2CF3, H, OCF3], [AA3315; 2, CH, Et, CH2CHF2, H, OCF3], [AA3316; 0, N, Et, H, H, OCF3], [AA3317; 0, N, Et, F, H, OCF3], [AA3318; 0, N, Et, Cl, H, OCF3], [AA3319; 0, N, Et, Br, H, OCF3], [AA3320; 0, N, Et, I, H, OCF3], [AA3321; 0, N, Et, CF3, H, OCF3], [AA3322; 0, N, Et, CF2H, H, OCF3], [AA3323; 0, N, Et, C2F5, H, OCF3], [AA3324; 0, N, Et, C3F7, H, OCF3], [AA3325; 0, N, Et, CH2CF3, H, OCF3], [AA3326; 0, N, Et, CH2CHF2, H, OCF3], [AA3327; 1, N, Et, H, H, OCF3], [AA3328; 1, N, Et, F, H, OCF3], [AA3329; 1, N, Et, Cl, H, OCF3], [AA3330; 1, N, Et, Br, H, OCF3], [AA3331; 1, N, Et, I, H, OCF3], [AA3332; 1, N, Et, CF3, H, OCF3], [AA3333; 1, N, Et, CF2H, H, OCF3], [AA3334; 1, N, Et, C2F5, H, OCF3], [AA3335; 1, N, Et, C3F7, H, OCF3], [AA3336; 1, N, Et, CH2CF3, H, OCF3], [AA3337;[1, N, Et, CH2CHF2, H, OCF3], [AA3338; 2, N, Et, H, H, OCF3], [AA3339; 2, N, Et, F, H, OCF3], [AA3340; 2, N, Et, Cl, H, OCF3], [AA3341; 2, N, Et, Br, H, OCF3], [AA3342; 2, N, Et, I, H, OCF3], [AA3343; 2, N, Et, CF3, H, OCF3], [AA3344; 2, N, Et, CF2H, H, OCF3], [AA3345; 2, N, Et, C2F5, H, OCF3], [AA3346; 2, N, Et, C3F7, H, OCF3], [AA3347; 2, N, Et, CH2CF3, H, OCF3], [AA3348; 2, N, Et, CH2CHF2, H, OCF3], [AA3349; 0, CH, iPr, H, H, OCF3], [AA3350; 0, CH, iPr, F, H, OCF3], [AA3351; 0, CH, iPr, Cl, H, OCF3], [AA3352; 0, CH, iPr, Br, H, OCF3], [AA3353; 0, CH, iPr, I, H, OCF3], [AA3354; 0, CH, iPr, CF3, H, OCF3], [AA3355; 0, CH, iPr, CF2H, H, OCF3], [AA3356; 0, CH, iPr, C2F5, H, OCF3], [AA3357; 0, CH, iPr, C3F7, H, OCF3], [AA3358; 0, CH, iPr, CH2CF3, H, OCF3], [AA3359; 0, CH, iPr, CH2CHF2, H, OCF3], [AA3360; 1, CH, iPr, H, H, OCF3], [AA3361; 1, CH, iPr, F, H, OCF3], [AA3362; 1, CH, iPr, Cl, H, OCF3], [AA3363; 1, CH, iPr, Br, H, OCF3], [AA3364; 1, CH, iPr, I, H, OCF3], [AA3365; 1, CH, iPr, CF3, H, OCF3], [AA3366; 1, CH, iPr, CF2H, H, OCF3], [AA3367; 1, CH, iPr, C2F5, H, OCF3], [AA3368; 1, CH, iPr, C3F7, H, OCF3], [AA3369; 1, CH, iPr, CH2CF3, H, OCF3], [AA3370; 1, CH, iPr, CH2CHF2, H, OCF3], [AA3371; 2, CH, iPr, H, H, OCF3], [AA3372;[2, CH, iPr, F, H, OCF3], [AA3373; 2, CH, iPr, Cl, H, OCF3], [AA3374; 2, CH, iPr, Br, H, OCF3], [AA3375; 2, CH, iPr, I, H, OCF3], [AA3376; 2, CH, iPr, CF3, H, OCF3], [AA3377; 2, CH, iPr, CF2H, H, OCF3], [AA3378; 2, CH, iPr, C2F5, H, OCF3], [AA3379; 2, CH, iPr, C3F7, H, OCF3], [AA3380; 2, CH, iPr, CH2CF3, H, OCF3], [AA3381; 2, CH, iPr, CH2CHF2, H, OCF3], [AA3382; 0, N, iPr, H, H, OCF3], [AA3383; 0, N, iPr, F, H, OCF3], [AA3384; 0, N, iPr, Cl, H, OCF3], [AA3385; 0, N, iPr, Br, H, OCF3], [AA3386; 0, N, iPr, I, H, OCF3], [AA3387; 0, N, iPr, CF3, H, OCF3], [AA3388; 0, N, iPr, CF2H, H, OCF3], [AA3389; 0, N, iPr, C2F5, H, OCF3], [AA3390; 0, N, iPr, C3F7, H, OCF3], [AA3391; 0, N, iPr, CH2CF3, H, OCF3], [AA3392; 0, N, iPr, CH2CHF2, H, OCF3], [AA3393; 1, N, iPr, H, H, OCF3], [AA3394; 1, N, iPr, F, H, OCF3], [AA3395; 1, N, iPr, Cl, H, OCF3], [AA3396; 1, N, iPr, Br, H, OCF3], [AA3397; 1, N, iPr, I, H, OCF3], [AA3398; 1, N, iPr, CF3, H, OCF3], [AA3399; 1, N, iPr, CF2H, H, OCF3], [AA3400; 1, N, iPr, C2F5, H, OCF3], [AA3401; 1, N, iPr, C3F7, H, OCF3], [AA3402; 1, N, iPr, CH2CF3, H, OCF3], [AA3403; 1, N, iPr, CH2CHF2, H, OCF3], [AA3404; 2, N, iPr, H, H, OCF3], [AA3405; 2, N, iPr, F, H, OCF3], [AA3406; 2, N, iPr, Cl, H, OCF3], [AA3407;[2,N,iPr,Br,H,OCF3], [AA3408; 2,N,iPr,I,H,OCF3], [AA3409; 2,N,iPr,CF3,H,OCF3], [AA3410; 2,N,iPr,CF2H,H,OCF3], [AA3411; 2,N,iPr,C2F5,H,OCF3], [AA3412; 2,N,iPr,C3F7,H,OCF3], [AA3413; 2,N,iPr,CH2CF3,H,OCF3], [AA3414; 2,N,iPr,CH2CHF2,H,OCF3], [AA3415; 0,CH,cPr,H,H,OCF3], [AA3416; 0,CH,cPr,F,H,OCF3], [AA3417; 0,CH,cPr,Cl,H,OCF3], [AA3418; 0,CH,cPr,Br,H,OCF3], [AA3419; 0,CH,cPr,I,H,OCF3], [AA3420; 0,CH,cPr,CF3,H,OCF3], [AA3421; 0,CH,cPr,CF2H,H,OCF3], [AA3422; 0,CH,cPr,C2F5,H,OCF3], [AA3423; 0,CH,cPr,C3F7,H,OCF3], [AA3424; 0,CH,cPr,CH2CF3,H,OCF3], [AA3425; 0,CH,cPr,CH2CHF2,H,OCF3], [AA3426; 1,CH,cPr,H,H,OCF3], [AA3427; 1,CH,cPr,F,H,OCF3], [AA3428; 1,CH,cPr,Cl,H,OCF3], [AA3429; 1,CH,cPr,Br,H,OCF3], [AA3430; 1,CH,cPr,I,H,OCF3], [AA3431; 1,CH,cPr,CF3,H,OCF3], [AA3432; 1,CH,cPr,CF2H,H,OCF3], [AA3433; 1,CH,cPr,C2F5,H,OCF3], [AA3434; 1,CH,cPr,C3F7,H,OCF3], [AA3435; 1,CH,cPr,CH2CF3,H,OCF3], [AA3436; 1,CH,cPr,CH2CHF2,H,OCF3], [AA3437; 2,CH,cPr,H,H,OCF3], [AA3438; 2,CH,cPr,F,H,OCF3], [AA3439; 2,CH,cPr,Cl,H,OCF3], [AA3440; 2,CH,cPr,Br,H,OCF3], [AA3441;[2,CH,cPr,I,H,OCF3], [AA3442; 2,CH,cPr,CF3,H,OCF3], [AA3443; 2,CH,cPr,CF2H,H,OCF3], [AA3444; 2,CH,cPr,C2F5,H,OCF3], [AA3445; 2,CH,cPr,C3F7,H,OCF3], [AA3446; 2,CH,cPr,CH2CF3,H,OCF3], [AA3447; 2,CH,cPr,CH2CHF2,H,OCF3], [AA3448; 0,N,cPr,H,H,OCF3], [AA3449; 0,N,cPr,F,H,OCF3], [AA3450; 0,N,cPr,Cl,H,OCF3], [AA3451; 0,N,cPr,Br,H,OCF3], [AA3452; 0,N,cPr,I,H,OCF3], [AA3453; 0,N,cPr,CF3,H,OCF3], [AA3454; 0,N,cPr,CF2H,H,OCF3], [AA3455; 0,N,cPr,C2F5,H,OCF3], [AA3456; 0,N,cPr,C3F7,H,OCF3], [AA3457; 0,N,cPr,CH2CF3,H,OCF3], [AA3458; 0,N,cPr,CH2CHF2,H,OCF3], [AA3459; 1,N,cPr,H,H,OCF3], [AA3460; 1,N,cPr,F,H,OCF3], [AA3461; 1,N,cPr,Cl,H,OCF3], [AA3462; 1,N,cPr,Br,H,OCF3], [AA3463; 1,N,cPr,I,H,OCF3], [AA3464; 1,N,cPr,CF3,H,OCF3], [AA3465; 1,N,cPr,CF2H,H,OCF3], [AA3466; 1,N,cPr,C2F5,H,OCF3], [AA3467; 1,N,cPr,C3F7,H,OCF3], [AA3468; 1,N,cPr,CH2CF3,H,OCF3], [AA3469; 1,N,cPr,CH2CHF2,H,OCF3], [AA3470; 2,N,cPr,H,H,OCF3], [AA3471; 2,N,cPr,F,H,OCF3], [AA3472; 2,N,cPr,Cl,H,OCF3], [AA3473; 2,N,cPr,Br,H,OCF3], [AA3474; 2,N,cPr,I,H,OCF3], [AA3475; 2,N,cPr,CF3,H,OCF3], [AA3476;[2,N,cPr,CF2H,H,OCF3], [AA3477; 2,N,cPr,C2F5,H,OCF3], [AA3478; 2,N,cPr,C3F7,H,OCF3], [AA3479; 2,N,cPr,CH2CF3,H,OCF3], [AA3480; 2,N,cPr,CH2CHF2,H,OCF3], [AA3481; 0,CH,H,H,F,OCF3], [AA3482; 0,CH,H,H,Cl,OCF3], [AA3483; 0,CH,H,H,Br,OCF3], [AA3484; 0,CH,H,H,I,OCF3], [AA3485; 0,CH,H,H,CF3,OCF3], [AA3486; 0,CH,H,H,CF2H,OCF3], [AA3487; 0,CH,H,H,C2F5,OCF3], [AA3488; 0,CH,H,H,C3F7,OCF3], [AA3489; 0,CH,H,H,CH2CF3,OCF3], [AA3490; 0,CH,H,H,CH2CHF2,OCF3], [AA3491; 1,CH,H,H,F,OCF3], [AA3492; 1,CH,H,H,Cl,OCF3], [AA3493; 1,CH,H,H,Br,OCF3], [AA3494; 1,CH,H,H,I,OCF3], [AA3495; 1,CH,H,H,CF3,OCF3], [AA3496; 1,CH,H,H,CF2H,OCF3], [AA3497; 1,CH,H,H,C2F5,OCF3], [AA3498; 1,CH,H,H,C3F7,OCF3], [AA3499; 1,CH,H,H,CH2CF3,OCF3], [AA3500; 1,CH,H,H,CH2CHF2,OCF3], [AA3501; 2,CH,H,H,F,OCF3], [AA3502; 2,CH,H,H,Cl,OCF3], [AA3503; 2,CH,H,H,Br,OCF3], [AA3504; 2,CH,H,H,I,OCF3], [AA3505; 2,CH,H,H,CF3,OCF3], [AA3506; 2,CH,H,H,CF2H,OCF3], [AA3507; 2,CH,H,H,C2F5,OCF3], [AA3508; 2,CH,H,H,C3F7,OCF3], [AA3509; 2,CH,H,H,CH2CF3,OCF3], [AA3510; 2,CH,H,H,CH2CHF2,OCF3], [AA3511; 0,N,H,H,F,OCF3], [AA3512;[0, N, H, H, Cl, OCF3], [AA3513; 0, N, H, H, Br, OCF3], [AA3514; 0, N, H, H, I, OCF3], [AA3515; 0, N, H, H, CF3, OCF3], [AA3516; 0, N, H, H, CF2H, OCF3], [AA3517; 0, N, H, H, C2F5, OCF3], [AA3518; 0, N, H, H, C3F7, OCF3], [AA3519; 0, N, H, H, CH2CF3, OCF3], [AA3520; 0, N, H, H, CH2CHF2, OCF3], [AA3521; 1, N, H, H, F, OCF3], [AA3522; 1, N, H, H, Cl, OCF3], [AA3523; 1, N, H, H, Br, OCF3], [AA3524; 1, N, H, H, I, OCF3], [AA3525; 1, N, H, H, CF3, OCF3], [AA3526; 1, N, H, H, CF2H, OCF3], [AA3527; 1, N, H, H, C2F5, OCF3], [AA3528; 1, N, H, H, C3F7, OCF3], [AA3529; 1, N, H, H, CH2CF3, OCF3], [AA3530; 1, N, H, H, CH2CHF2, OCF3], [AA3531; 2, N, H, H, F, OCF3], [AA3532; 2, N, H, H, Cl, OCF3], [AA3533; 2, N, H, H, Br, OCF3], [AA3534; 2, N, H, H, I, OCF3], [AA3535; 2, N, H, H, CF3, OCF3], [AA3536; 2, N, H, H, CF2H, OCF3], [AA3537; 2, N, H, H, C2F5, OCF3], [AA3538; 2, N, H, H, C3F7, OCF3], [AA3539; 2, N, H, H, CH2CF3, OCF3], [AA3540; 2, N, H, H, CH2CHF2, OCF3], [AA3541; 0, CH, Me, H, F, OCF3], [AA3542; 0, CH, Me, H, Cl, OCF3], [AA3543; 0, CH, Me, H, Br, OCF3], [AA3544; 0, CH, Me, H, I, OCF3], [AA3545; 0, CH, Me, H, CF3, OCF3], [AA3546; 0, CH, Me, H, CF2H, OCF3], [AA3547; 0, CH, Me, H, C2F5, OCF3], [AA3548; 0, CH, Me, H, C3F7, OCF3], [AA3549;[0, CH, Me, H, CH2CF3, OCF3], [AA3550; 0, CH, Me, H, CH2CHF2, OCF3], [AA3551; 1, CH, Me, H, F, OCF3], [AA3552; 1, CH, Me, H, Cl, OCF3], [AA3553; 1, CH, Me, H, Br, OCF3], [AA3554; 1, CH, Me, H, I, OCF3], [AA3555; 1, CH, Me, H, CF3, OCF3], [AA3556; 1, CH, Me, H, CF2H, OCF3], [AA3557; 1, CH, Me, H, C2F5, OCF3], [AA3558; 1, CH, Me, H, C3F7, OCF3], [AA3559; 1, CH, Me, H, CH2CF3, OCF3], [AA3560; 1, CH, Me, H, CH2CHF2, OCF3], [AA3561; 2, CH, Me, H, F, OCF3], [AA3562; 2, CH, Me, H, Cl, OCF3], [AA3563; 2, CH, Me, H, Br, OCF3], [AA3564; 2, CH, Me, H, I, OCF3], [AA3565; 2, CH, Me, H, CF3, OCF3], [AA3566; 2, CH, Me, H, CF2H, OCF3], [AA3567; 2, CH, Me, H, C2F5, OCF3], [AA3568; 2, CH, Me, H, C3F7, OCF3], [AA3569; 2, CH, Me, H, CH2CF3, OCF3], [AA3570; 2, CH, Me, H, CH2CHF2, OCF3], [AA3571; 0, N, Me, H, F, OCF3], [AA3572; 0, N, Me, H, Cl, OCF3], [AA3573; 0, N, Me, H, Br, OCF3], [AA3574; 0, N, Me, H, I, OCF3], [AA3575; 0, N, Me, H, CF3, OCF3], [AA3576; 0, N, Me, H, CF2H, OCF3], [AA3577; 0, N, Me, H, C2F5, OCF3], [AA3578; 0, N, Me, H, C3F7, OCF3], [AA3579; 0, N, Me, H, CH2CF3, OCF3], [AA3580; 0, N, Me, H, CH2CHF2, OCF3], [AA3581; 1, N, Me, H, F, OCF3], [AA3582; 1, N, Me, H, Cl, OCF3], [AA3583; 1, N, Me, H, Br, OCF3], [AA3584;[1,N,Me,H,I,OCF3], [AA3585; 1,N,Me,H,CF3,OCF3], [AA3586; 1,N,Me,H,CF2H,OCF3], [AA3587; 1,N,Me,H,C2F5,OCF3], [AA3588; 1,N,Me,H,C3F7,OCF3], [AA3589; 1,N,Me,H,CH2CF3,OCF3], [AA3590; 1,N,Me,H,CH2CHF2,OCF3], [AA3591; 2,N,Me,H,F,OCF3], [AA3592; 2,N,Me,H,Cl,OCF3], [AA3593; 2,N,Me,H,Br,OCF3], [AA3594; 2,N,Me,H,I,OCF3], [AA3595; 2,N,Me,H,CF3,OCF3], [AA3596; 2,N,Me,H,CF2H,OCF3], [AA3597; 2,N,Me,H,C2F5,OCF3], [AA3598; 2,N,Me,H,C3F7,OCF3], [AA3599; 2,N,Me,H,CH2CF3,OCF3], [AA3600; 2,N,Me,H,CH2CHF2,OCF3];
[0607] [AA3601; 0, CH, Et, H, F, OCF3], [AA3602; 0, CH, Et, H, Cl, OCF3], [AA3603; 0, CH, Et, H, Br, OCF3], [AA3604; 0, CH, Et, H, I, OCF3], [AA3605; 0, CH, Et, H, CF3, OCF3], [AA3606; 0, CH, Et, H, CF2H, OCF3], [AA3607; 0, CH, Et, H, C2F5, OCF3], [AA3608; 0, CH, Et, H, C3F7, OCF3], [AA3609; 0, CH, Et, H, CH2CF3, OCF3], [AA3610; 0, CH, Et, H, CH2CHF2, OCF3], [AA3611; 1, CH, Et, H, F, OCF3], [AA3612; 1, CH, Et, H, Cl, OCF3], [AA3613; 1, CH, Et, H, Br, OCF3], [AA3614; 1, CH, Et, H, I, OCF3], [AA3615; 1, CH, Et, H, CF3, OCF3], [AA3616; 1, CH, Et, H, CF2H, OCF3], [AA3617; 1, CH, Et, H, C2F5, OCF3], [AA3618; 1, CH, Et, H, C3F7, OCF3], [AA3619; 1, CH, Et, H, CH2CF3, OCF3], [AA3620; 1, CH, Et, H, CH2CHF2, OCF3], [AA3621; 2, CH, Et, H, F, OCF3], [AA3622; 2, CH, Et, H, Cl, OCF3], [AA3623; 2, CH, Et, H, Br, OCF3], [AA3624; 2, CH, Et, H, I, OCF3], [AA3625; 2, CH, Et, H, CF3, OCF3], [AA3626; 2, CH, Et, H, CF2H, OCF3], [AA3627; 2, CH, Et, H, C2F5, OCF3], [AA3628; 2, CH, Et, H, C3F7, OCF3], [AA3629; 2, CH, Et, H, CH2CF3, OCF3], [AA3630; 2, CH, Et, H, CH2CHF2, OCF3], [AA3631; 0, N, Et, H, F, OCF3], [AA3632; 0, N, Et, H, Cl, OCF3], [AA3633; 0, N, Et, H, Br, OCF3], [AA3634; 0, N, Et, H, I, OCF3], [AA3635; 0, N, Et, H, CF3, OCF3], [AA3636;[0, N, Et, H, CF2H, OCF3], [AA3637; 0, N, Et, H, C2F5, OCF3], [AA3638; 0, N, Et, H, C3F7, OCF3], [AA3639; 0, N, Et, H, CH2CF3, OCF3], [AA3640; 0, N, Et, H, CH2CHF2, OCF3], [AA3641; 1, N, Et, H, F, OCF3], [AA3642; 1, N, Et, H, Cl, OCF3], [AA3643; 1, N, Et, H, Br, OCF3], [AA3644; 1, N, Et, H, I, OCF3], [AA3645; 1, N, Et, H, CF3, OCF3], [AA3646; 1, N, Et, H, CF2H, OCF3], [AA3647; 1, N, Et, H, C2F5, OCF3], [AA3648; 1, N, Et, H, C3F7, OCF3], [AA3649; 1, N, Et, H, CH2CF3, OCF3], [AA3650; 1, N, Et, H, CH2CHF2, OCF3], [AA3651; 2, N, Et, H, F, OCF3], [AA3652; 2, N, Et, H, Cl, OCF3], [AA3653; 2, N, Et, H, Br, OCF3], [AA3654; 2, N, Et, H, I, OCF3], [AA3655; 2, N, Et, H, CF3, OCF3], [AA3656; 2, N, Et, H, CF2H, OCF3], [AA3657; 2, N, Et, H, C2F5, OCF3], [AA3658; 2, N, Et, H, C3F7, OCF3], [AA3659; 2, N, Et, H, CH2CF3, OCF3], [AA3660; 2, N, Et, H, CH2CHF2, OCF3], [AA3661; 0, CH, iPr, H, F, OCF3], [AA3662; 0, CH, iPr, H, Cl, OCF3], [AA3663; 0, CH, iPr, H, Br, OCF3], [AA3664; 0, CH, iPr, H, I, OCF3], [AA3665; 0, CH, iPr, H, CF3, OCF3], [AA3666; 0, CH, iPr, H, CF2H, OCF3], [AA3667; 0, CH, iPr, H, C2F5, OCF3], [AA3668; 0, CH, iPr, H, C3F7, OCF3], [AA3669; 0, CH, iPr, H, CH2CF3, OCF3], [AA3670; 0, CH, iPr, H, CH2CHF2, OCF3], [AA3671;[1, CH, iPr, H, F, OCF3], [AA3672; 1, CH, iPr, H, Cl, OCF3], [AA3673; 1, CH, iPr, H, Br, OCF3], [AA3674; 1, CH, iPr, H, I, OCF3], [AA3675; 1, CH, iPr, H, CF3, OCF3], [AA3676; 1, CH, iPr, H, CF2H, OCF3], [AA3677; 1, CH, iPr, H, C2F5, OCF3], [AA3678; 1, CH, iPr, H, C3F7, OCF3], [AA3679; 1, CH, iPr, H, CH2CF3, OCF3], [AA3680; 1, CH, iPr, H, CH2CHF2, OCF3], [AA3681; 2, CH, iPr, H, F, OCF3], [AA3682; 2, CH, iPr, H, Cl, OCF3], [AA3683; 2, CH, iPr, H, Br, OCF3], [AA3684; 2, CH, iPr, H, I, OCF3], [AA3685; 2, CH, iPr, H, CF3, OCF3], [AA3686; 2, CH, iPr, H, CF2H, OCF3], [AA3687; 2, CH, iPr, H, C2F5, OCF3], [AA3688; 2, CH, iPr, H, C3F7, OCF3], [AA3689; 2, CH, iPr, H, CH2CF3, OCF3], [AA3690; 2, CH, iPr, H, CH2CHF2, OCF3], [AA3691; 0, N, iPr, H, F, OCF3], [AA3692; 0, N, iPr, H, Cl, OCF3], [AA3693; 0, N, iPr, H, Br, OCF3], [AA3694; 0, N, iPr, H, I, OCF3], [AA3695; 0, N, iPr, H, CF3, OCF3], [AA3696; 0, N, iPr, H, CF2H, OCF3], [AA3697; 0, N, iPr, H, C2F5, OCF3], [AA3698; 0, N, iPr, H, C3F7, OCF3], [AA3699; 0, N, iPr, H, CH2CF3, OCF3], [AA3700; 0, N, iPr, H, CH2CHF2, OCF3], [AA3701; 1, N, iPr, H, F, OCF3], [AA3702; 1, N, iPr, H, Cl, OCF3], [AA3703; 1, N, iPr, H, Br, OCF3], [AA3704; 1, N, iPr, H, I, OCF3], [AA3705;[1,N,iPr,H,CF3,OCF3], [AA3706; 1,N,iPr,H,CF2H,OCF3], [AA3707; 1,N,iPr,H,C2F5,OCF3], [AA3708; 1,N,iPr,H,C3F7,OCF3], [AA3709; 1,N,iPr,H,CH2CF3,OCF3], [AA3710; 1,N,iPr,H,CH2CHF2,OCF3], [AA3711; 2,N,iPr,H,F,OCF3], [AA3712; 2,N,iPr,H,Cl,OCF3], [AA3713; 2,N,iPr,H,Br,OCF3], [AA3714; 2,N,iPr,H,I,OCF3], [AA3715; 2,N,iPr,H,CF3,OCF3], [AA3716; 2,N,iPr,H,CF2H,OCF3], [AA3717; 2,N,iPr,H,C2F5,OCF3], [AA3718; 2,N,iPr,H,C3F7,OCF3], [AA3719; 2,N,iPr,H,CH2CF3,OCF3], [AA3720; 2,N,iPr,H,CH2CHF2,OCF3], [AA3721; 0,CH,cPr,H,F,OCF3], [AA3722; 0,CH,cPr,H,Cl,OCF3], [AA3723; 0,CH,cPr,H,Br,OCF3], [AA3724; 0,CH,cPr,H,I,OCF3], [AA3725; 0,CH,cPr,H,CF3,OCF3], [AA3726; 0,CH,cPr,H,CF2H,OCF3], [AA3727; 0,CH,cPr,H,C2F5,OCF3], [AA3728; 0,CH,cPr,H,C3F7,OCF3], [AA3729; 0,CH,cPr,H,CH2CF3,OCF3], [AA3730; 0,CH,cPr,H,CH2CHF2,OCF3], [AA3731; 1,CH,cPr,H,F,OCF3], [AA3732; 1,CH,cPr,H,Cl,OCF3], [AA3733; 1,CH,cPr,H,Br,OCF3], [AA3734; 1,CH,cPr,H,I,OCF3], [AA3735; 1,CH,cPr,H,CF3,OCF3], [AA3736; 1,CH,cPr,H,CF2H,OCF3], [AA3737; 1,CH,cPr,H,C2F5,OCF3], [AA3738; 1,CH,cPr,H,C3F7,OCF3], [AA3739;1,CH,cPr,H,CH2CF3,OCF3], [AA3740; 1,CH,cPr,H,CH2CHF2,OCF3], [AA3741; 2,CH,cPr,H,F,OCF3], [AA3742; 2,CH,cPr,H,Cl,OCF3], [AA3743; 2,CH,cPr,H,Br,OCF3], [AA3744; 2,CH,cPr,H,I,OCF3], [AA3745; 2,CH,cPr,H,CF3,OCF3], [AA3746; 2,CH,cPr,H,CF2H,OCF3], [AA3747; 2,CH,cPr,H,C2F5,OCF3], [AA3748; 2,CH,cPr,H,C3F7,OCF3], [AA3749; 2,CH,cPr,H,CH2CF3,OCF3], [AA3750; 2,CH,cPr,H,CH2CHF2,OCF3], [AA3751; 0,N,cPr,H,F,OCF3], [AA3752; 0,N,cPr,H,Cl,OCF3], [AA3753; 0,N,cPr,H,Br,OCF3], [AA3754; 0,N,cPr,H,I,OCF3], [AA3755; 0,N,cPr,H,CF3,OCF3], [AA3756; 0,N,cPr,H,CF2H,OCF3], [AA3757; 0,N,cPr,H,C2F5,OCF3], [AA3758; 0,N,cPr,H,C3F7,OCF3], [AA3759; 0,N,cPr,H,CH2CF3,OCF3], [AA3760; 0,N,cPr,H,CH2CHF2,OCF3], [AA3761; 1,N,cPr,H,F,OCF3], [AA3762; 1,N,cPr,H,Cl,OCF3], [AA3763; 1,N,cPr,H,Br,OCF3], [AA3764; 1,N,cPr,H,I,OCF3], [AA3765; 1,N,cPr,H,CF3,OCF3], [AA3766; 1,N,cPr,H,CF2H,OCF3], [AA3767; 1,N,cPr,H,C2F5,OCF3], [AA3768; 1,N,cPr,H,C3F7,OCF3], [AA3769; 1,N,cPr,H,CH2CF3,OCF3], [AA3770; 1,N,cPr,H,CH2CHF2,OCF3], [AA3771; 2,N,cPr,H,F,OCF3], [AA3772; 2,N,cPr,H,Cl,OCF3], [AA3773;[2,N,cPr,H,Br,OCF3], [AA3774; 2,N,cPr,H,I,OCF3], [AA3775; 2,N,cPr,H,CF3,OCF3], [AA3776; 2,N,cPr,H,CF2H,OCF3], [AA3777; 2,N,cPr,H,C2F5,OCF3], [AA3778; 2,N,cPr,H,C3F7,OCF3], [AA3779; 2,N,cPr,H,CH2CF3,OCF3], [AA3780; 2,N,cPr,H,CH2CHF2,OCF3], [AA3781; 0,CH,H,H,H,OCHF2], [AA3782; 0,CH,H,F,H,OCHF2], [AA3783; 0,CH,H,Cl,H,OCHF2], [AA3784; 0,CH,H,Br,H,OCHF2], [AA3785; 0,CH,H,I,H,OCHF2], [AA3786; 0,CH,H,CF3,H,OCHF2], [AA3787; 0,CH,H,CF2H,H,OCHF2], [AA3788; 0,CH,H,C2F5,H,OCHF2], [AA3789; 0,CH,H,C3F7,H,OCHF2], [AA3790; 0,CH,H,CH2CF3,H,OCHF2], [AA3791; 0,CH,H,CH2CHF2,H,OCHF2], [AA3792; 1,CH,H,H,H,OCHF2], [AA3793; 1,CH,H,F,H,OCHF2], [AA3794; 1,CH,H,Cl,H,OCHF2], [AA3795; 1,CH,H,Br,H,OCHF2], [AA3796; 1,CH,H,I,H,OCHF2], [AA3797; 1,CH,H,CF3,H,OCHF2], [AA3798; 1,CH,H,CF2H,H,OCHF2], [AA3799; 1,CH,H,C2F5,H,OCHF2], [AA3800; 1,CH,H,C3F7,H,OCHF2], [AA3801; 1,CH,H,CH2CF3,H,OCHF2], [AA3802; 1,CH,H,CH2CHF2,H,OCHF2], [AA3803; 2,CH,H,H,H,OCHF2], [AA3804; 2,CH,H,F,H,OCHF2], [AA3805; 2,CH,H,Cl,H,OCHF2], [AA3806; 2,CH,H,Br,H,OCHF2], [AA3807; 2,CH,H,I,H,OCHF2], [AA3808;[2, CH, H, CF3, H, OCHF2], [AA3809; 2, CH, H, CF2H, H, OCHF2], [AA3810; 2, CH, H, C2F5, H, OCHF2], [AA3811; 2, CH, H, C3F7, H, OCHF2], [AA3812; 2, CH, H, CH2CF3, H, OCHF2], [AA3813; 2, CH, H, CH2CHF2, H, OCHF2], [AA3814; 0, N, H, H, H, OCHF2], [AA3815; 0, N, H, F, H, OCHF2], [AA3816; 0, N, H, Cl, H, OCHF2], [AA3817; 0, N, H, Br, H, OCHF2], [AA3818; 0, N, H, I, H, OCHF2], [AA3819; 0, N, H, CF3, H, OCHF2], [AA3820; 0, N, H, CF2H, H, OCHF2], [AA3821; 0, N, H, C2F5, H, OCHF2], [AA3822; 0, N, H, C3F7, H, OCHF2], [AA3823; 0, N, H, CH2CF3, H, OCHF2], [AA3824; 0, N, H, CH2CHF2, H, OCHF2], [AA3825; 1, N, H, H, H, OCHF2], [AA3826; 1, N, H, F, H, OCHF2], [AA3827; 1, N, H, Cl, H, OCHF2], [AA3828; 1, N, H, Br, H, OCHF2], [AA3829; 1, N, H, I, H, OCHF2], [AA3830; 1, N, H, CF3, H, OCHF2], [AA3831; 1, N, H, CF2H, H, OCHF2], [AA3832; 1, N, H, C2F5, H, OCHF2], [AA3833; 1, N, H, C3F7, H, OCHF2], [AA3834; 1, N, H, CH2CF3, H, OCHF2], [AA3835; 1, N, H, CH2CHF2, H, OCHF2], [AA3836; 2, N, H, H, H, OCHF2], [AA3837; 2, N, H, F, H, OCHF2], [AA3838; 2, N, H, Cl, H, OCHF2], [AA3839; 2, N, H, Br, H, OCHF2], [AA3840; 2, N, H, I, H, OCHF2], [AA3841; 2, N, H, CF3, H, OCHF2], [AA3842; 2, N, H, CF2H, H, OCHF2], [AA3843; 2, N, H, C2F5, H, OCHF2], [AA3844;[2,N,H,C3F7,H,OCHF2], [AA3845; 2,N,H,CH2CF3,H,OCHF2], [AA3846; 2,N,H,CH2CHF2,H,OCHF2], [AA3847; 0,CH,Me,H,H,OCHF2], [AA3848; 0,CH,Me,F,H,OCHF2], [AA3849; 0,CH,Me,Cl,H,OCHF2], [AA3850; 0,CH,Me,Br,H,OCHF2], [AA3851; 0,CH,Me,I,H,OCHF2], [AA3852; 0,CH,Me,CF3,H,OCHF2], [AA3853; 0,CH,Me,CF2H,H,OCHF2], [AA3854; 0,CH,Me,C2F5,H,OCHF2], [AA3855; 0,CH,Me,C3F7,H,OCHF2], [AA3856; 0,CH,Me,CH2CF3,H,OCHF2], [AA3857; 0,CH,Me,CH2CHF2,H,OCHF2], [AA3858; 1,CH,Me,H,H,OCHF2], [AA3859; 1,CH,Me,F,H,OCHF2], [AA3860; 1,CH,Me,Cl,H,OCHF2], [AA3861; 1,CH,Me,Br,H,OCHF2], [AA3862; 1,CH,Me,I,H,OCHF2], [AA3863; 1,CH,Me,CF3,H,OCHF2], [AA3864; 1,CH,Me,CF2H,H,OCHF2], [AA3865; 1,CH,Me,C2F5,H,OCHF2], [AA3866; 1,CH,Me,C3F7,H,OCHF2], [AA3867; 1,CH,Me,CH2CF3,H,OCHF2], [AA3868; 1,CH,Me,CH2CHF2,H,OCHF2], [AA3869; 2,CH,Me,H,H,OCHF2], [AA3870; 2,CH,Me,F,H,OCHF2], [AA3871; 2,CH,Me,Cl,H,OCHF2], [AA3872; 2,CH,Me,Br,H,OCHF2], [AA3873; 2,CH,Me,I,H,OCHF2], [AA3874; 2,CH,Me,CF3,H,OCHF2], [AA3875; 2,CH,Me,CF2H,H,OCHF2], [AA3876; 2,CH,Me,C2F5,H,OCHF2], [AA3877; 2,CH,Me,C3F7,H,OCHF2], [AA3878;[2, CH, Me, CH2CF3, H, OCHF2], [AA3879; 2, CH, Me, CH2CHF2, H, OCHF2], [AA3880; 0, N, Me, H, H, OCHF2], [AA3881; 0, N, Me, F, H, OCHF2], [AA3882; 0, N, Me, Cl, H, OCHF2], [AA3883; 0, N, Me, Br, H, OCHF2], [AA3884; 0, N, Me, I, H, OCHF2], [AA3885; 0, N, Me, CF3, H, OCHF2], [AA3886; 0, N, Me, CF2H, H, OCHF2], [AA3887; 0, N, Me, C2F5, H, OCHF2], [AA3888; 0, N, Me, C3F7, H, OCHF2], [AA3889; 0, N, Me, CH2CF3, H, OCHF2], [AA3890; 0, N, Me, CH2CHF2, H, OCHF2], [AA3891; 1, N, Me, H, H, OCHF2], [AA3892; 1, N, Me, F, H, OCHF2], [AA3893; 1, N, Me, Cl, H, OCHF2], [AA3894; 1, N, Me, Br, H, OCHF2], [AA3895; 1, N, Me, I, H, OCHF2], [AA3896; 1, N, Me, CF3, H, OCHF2], [AA3897; 1, N, Me, CF2H, H, OCHF2], [AA3898; 1, N, Me, C2F5, H, OCHF2], [AA3899; 1, N, Me, C3F7, H, OCHF2], [AA3900; 1, N, Me, CH2CF3, H, OCHF2], [AA3901; 1, N, Me, CH2CHF2, H, OCHF2], [AA3902; 2, N, Me, H, H, OCHF2], [AA3903; 2, N, Me, F, H, OCHF2], [AA3904; 2, N, Me, Cl, H, OCHF2], [AA3905; 2, N, Me, Br, H, OCHF2], [AA3906; 2, N, Me, I, H, OCHF2], [AA3907; 2, N, Me, CF3, H, OCHF2], [AA3908; 2, N, Me, CF2H, H, OCHF2], [AA3909; 2, N, Me, C2F5, H, OCHF2], [AA3910; 2, N, Me, C3F7, H, OCHF2], [AA3911; 2, N, Me, CH2CF3, H, OCHF2], [AA3912; 2, N, Me, CH2CHF2, H, OCHF2], [AA3913;[0, CH, Et, H, H, OCHF2], [AA3914; 0, CH, Et, F, H, OCHF2], [AA3915; 0, CH, Et, Cl, H, OCHF2], [AA3916; 0, CH, Et, Br, H, OCHF2], [AA3917; 0, CH, Et, I, H, OCHF2], [AA3918; 0, CH, Et, CF3, H, OCHF2], [AA3919; 0, CH, Et, CF2H, H, OCHF2], [AA3920; 0, CH, Et, C2F5, H, OCHF2], [AA3921; 0, CH, Et, C3F7, H, OCHF2], [AA3922; 0, CH, Et, CH2CF3, H, OCHF2], [AA3923; 0, CH, Et, CH2CHF2, H, OCHF2], [AA3924; 1, CH, Et, H, H, OCHF2], [AA3925; 1, CH, Et, F, H, OCHF2], [AA3926; 1, CH, Et, Cl, H, OCHF2], [AA3927; 1, CH, Et, Br, H, OCHF2], [AA3928; 1, CH, Et, I, H, OCHF2], [AA3929; 1, CH, Et, CF3, H, OCHF2], [AA3930; 1, CH, Et, CF2H, H, OCHF2], [AA3931; 1, CH, Et, C2F5, H, OCHF2], [AA3932; 1, CH, Et, C3F7, H, OCHF2], [AA3933; 1, CH, Et, CH2CF3, H, OCHF2], [AA3934; 1, CH, Et, CH2CHF2, H, OCHF2], [AA3935; 2, CH, Et, H, H, OCHF2], [AA3936; 2, CH, Et, F, H, OCHF2], [AA3937; 2, CH, Et, Cl, H, OCHF2], [AA3938; 2, CH, Et, Br, H, OCHF2], [AA3939; 2, CH, Et, I, H, OCHF2], [AA3940; 2, CH, Et, CF3, H, OCHF2], [AA3941; 2, CH, Et, CF2H, H, OCHF2], [AA3942; 2, CH, Et, C2F5, H, OCHF2], [AA3943; 2, CH, Et, C3F7, H, OCHF2], [AA3944; 2, CH, Et, CH2CF3, H, OCHF2], [AA3945; 2, CH, Et, CH2CHF2, H, OCHF2], [AA3946; 0, N, Et, H, H, OCHF2], [AA3947;[0, N, Et, F, H, OCHF2], [AA3948; 0, N, Et, Cl, H, OCHF2], [AA3949; 0, N, Et, Br, H, OCHF2], [AA3950; 0, N, Et, I, H, OCHF2], [AA3951; 0, N, Et, CF3, H, OCHF2], [AA3952; 0, N, Et, CF2H, H, OCHF2], [AA3953; 0, N, Et, C2F5, H, OCHF2], [AA3954; 0, N, Et, C3F7, H, OCHF2], [AA3955; 0, N, Et, CH2CF3, H, OCHF2], [AA3956; 0, N, Et, CH2CHF2, H, OCHF2], [AA3957; 1, N, Et, H, H, OCHF2], [AA3958; 1, N, Et, F, H, OCHF2], [AA3959; 1, N, Et, Cl, H, OCHF2], [AA3960; 1, N, Et, Br, H, OCHF2], [AA3961; 1, N, Et, I, H, OCHF2], [AA3962; 1, N, Et, CF3, H, OCHF2], [AA3963; 1, N, Et, CF2H, H, OCHF2], [AA3964; 1, N, Et, C2F5, H, OCHF2], [AA3965; 1, N, Et, C3F7, H, OCHF2], [AA3966; 1, N, Et, CH2CF3, H, OCHF2], [AA3967; 1, N, Et, CH2CHF2, H, OCHF2], [AA3968; 2, N, Et, H, H, OCHF2], [AA3969; 2, N, Et, F, H, OCHF2], [AA3970; 2, N, Et, Cl, H, OCHF2], [AA3971; 2, N, Et, Br, H, OCHF2], [AA3972; 2, N, Et, I, H, OCHF2], [AA3973; 2, N, Et, CF3, H, OCHF2], [AA3974; 2, N, Et, CF2H, H, OCHF2], [AA3975; 2, N, Et, C2F5, H, OCHF2], [AA3976; 2, N, Et, C3F7, H, OCHF2], [AA3977; 2, N, Et, CH2CF3, H, OCHF2], [AA3978; 2, N, Et, CH2CHF2, H, OCHF2], [AA3979; 0, CH, iPr, H, H, OCHF2], [AA3980; 0, CH, iPr, F, H, OCHF2], [AA3981; 0, CH, iPr, Cl, H, OCHF2], [AA3982;[0, CH, iPr, Br, H, OCHF2], [AA3983; 0, CH, iPr, I, H, OCHF2], [AA3984; 0, CH, iPr, CF3, H, OCHF2], [AA3985; 0, CH, iPr, CF2H, H, OCHF2], [AA3986; 0, CH, iPr, C2F5, H, OCHF2], [AA3987; 0, CH, iPr, C3F7, H, OCHF2], [AA3988; 0, CH, iPr, CH2CF3, H, OCHF2], [AA3989; 0, CH, iPr, CH2CHF2, H, OCHF2], [AA3990; 1, CH, iPr, H, H, OCHF2], [AA3991; 1, CH, iPr, F, H, OCHF2], [AA3992; 1, CH, iPr, Cl, H, OCHF2], [AA3993; 1, CH, iPr, Br, H, OCHF2], [AA3994; 1, CH, iPr, I, H, OCHF2], [AA3995; 1, CH, iPr, CF3, H, OCHF2], [AA3996; 1, CH, iPr, CF2H, H, OCHF2], [AA3997; 1, CH, iPr, C2F5, H, OCHF2], [AA3998; 1, CH, iPr, C3F7, H, OCHF2], [AA3999; 1, CH, iPr, CH2CF3, H, OCHF2], [AA4000; 1, CH, iPr, CH2CHF2, H, OCHF2], [AA4001; 2, CH, iPr, H, H, OCHF2], [AA4002; 2, CH, iPr, F, H, OCHF2], [AA4003; 2, CH, iPr, Cl, H, OCHF2], [AA4004; 2, CH, iPr, Br, H, OCHF2], [AA4005; 2, CH, iPr, I, H, OCHF2], [AA4006; 2, CH, iPr, CF3, H, OCHF2], [AA4007; 2, CH, iPr, CF2H, H, OCHF2], [AA4008; 2, CH, iPr, C2F5, H, OCHF2], [AA4009; 2, CH, iPr, C3F7, H, OCHF2], [AA4010; 2, CH, iPr, CH2CF3, H, OCHF2], [AA4011; 2, CH, iPr, CH2CHF2, H, OCHF2], [AA4012; 0, N, iPr, H, H, OCHF2], [AA4013; 0, N, iPr, F, H, OCHF2], [AA4014; 0, N, iPr, Cl, H, OCHF2], [AA4015;[0, N, iPr, Br, H, OCHF2], [AA4016; 0, N, iPr, I, H, OCHF2], [AA4017; 0, N, iPr, CF3, H, OCHF2], [AA4018; 0, N, iPr, CF2H, H, OCHF2], [AA4019; 0, N, iPr, C2F5, H, OCHF2], [AA4020; 0, N, iPr, C3F7, H, OCHF2], [AA4021; 0, N, iPr, CH2CF3, H, OCHF2], [AA4022; 0, N, iPr, CH2CHF2, H, OCHF2], [AA4023; 1, N, iPr, H, H, OCHF2], [AA4024; 1, N, iPr, F, H, OCHF2], [AA4025; 1, N, iPr, Cl, H, OCHF2], [AA4026; 1, N, iPr, Br, H, OCHF2], [AA4027; 1, N, iPr, I, H, OCHF2], [AA4028; 1, N, iPr, CF3, H, OCHF2], [AA4029; 1, N, iPr, CF2H, H, OCHF2], [AA4030; 1, N, iPr, C2F5, H, OCHF2], [AA4031; 1, N, iPr, C3F7, H, OCHF2], [AA4032; 1, N, iPr, CH2CF3, H, OCHF2], [AA4033; 1, N, iPr, CH2CHF2, H, OCHF2], [AA4034; 2, N, iPr, H, H, OCHF2], [AA4035; 2, N, iPr, F, H, OCHF2], [AA4036; 2, N, iPr, Cl, H, OCHF2], [AA4037; 2, N, iPr, Br, H, OCHF2], [AA4038; 2, N, iPr, I, H, OCHF2], [AA4039; 2, N, iPr, CF3, H, OCHF2], [AA4040; 2, N, iPr, CF2H, H, OCHF2], [AA4041; 2, N, iPr, C2F5, H, OCHF2], [AA4042; 2, N, iPr, C3F7, H, OCHF2], [AA4043; 2, N, iPr, CH2CF3, H, OCHF2], [AA4044; 2, N, iPr, CH2CHF2, H, OCHF2], [AA4045; 0, CH, cPr, H, H, OCHF2], [AA4046; 0, CH, cPr, F, H, OCHF2], [AA4047; 0, CH, cPr, Cl, H, OCHF2], [AA4048; 0, CH, cPr, Br, H, OCHF2], [AA4049;0, CH, cPr, I, H, OCHF2], [AA4050; 0, CH, cPr, CF3, H, OCHF2], [AA4051; 0, CH, cPr, CF2H, H, OCHF2], [AA4052; 0, CH, cPr, C2F5, H, OCHF2], [AA4053; 0, CH, cPr, C3F7, H, OCHF2], [AA4054; 0, CH, cPr, CH2CF3, H, OCHF2], [AA4055; 0, CH, cPr, CH2CHF2, H, OCHF2], [AA4056; 1, CH, cPr, H, H, OCHF2], [AA4057; 1, CH, cPr, F, H, OCHF2], [AA4058; 1, CH, cPr, Cl, H, OCHF2], [AA4059; 1, CH, cPr, Br, H, OCHF2], [AA4060; 1, CH, cPr, I, H, OCHF2], [AA4061; 1, CH, cPr, CF3, H, OCHF2], [AA4062; 1, CH, cPr, CF2H, H, OCHF2], [AA4063; 1, CH, cPr, C2F5, H, OCHF2], [AA4064; 1, CH, cPr, C3F7, H, OCHF2], [AA4065; 1, CH, cPr, CH2CF3, H, OCHF2], [AA4066; 1, CH, cPr, CH2CHF2, H, OCHF2], [AA4067; 2, CH, cPr, H, H, OCHF2], [AA4068; 2, CH, cPr, F, H, OCHF2], [AA4069; 2, CH, cPr, Cl, H, OCHF2], [AA4070; 2, CH, cPr, Br, H, OCHF2], [AA4071; 2, CH, cPr, I, H, OCHF2], [AA4072; 2, CH, cPr, CF3, H, OCHF2], [AA4073; 2, CH, cPr, CF2H, H, OCHF2], [AA4074; 2, CH, cPr, C2F5, H, OCHF2], [AA4075; 2, CH, cPr, C3F7, H, OCHF2], [AA4076; 2, CH, cPr, CH2CF3, H, OCHF2], [AA4077; 2, CH, cPr, CH2CHF2, H, OCHF2], [AA4078; 0, N, cPr, H, H, OCHF2], [AA4079; 0, N, cPr, F, H, OCHF2], [AA4080; 0, N, cPr, Cl, H, OCHF2], [AA4081; 0, N, cPr, Br, H, OCHF2], [AA4082;0,N,cPr,I,H,OCHF2], [AA4083; 0,N,cPr,CF3,H,OCHF2], [AA4084; 0,N,cPr,CF2H,H,OCHF2], [AA4085; 0,N,cPr,C2F5,H,OCHF2], [AA4086; 0,N,cPr,C3F7,H,OCHF2], [AA4087; 0,N,cPr,CH2CF3,H,OCHF2], [AA4088; 0,N,cPr,CH2CHF2,H,OCHF2], [AA4089; 1,N,cPr,H,H,OCHF2], [AA4090; 1,N,cPr,F,H,OCHF2], [AA4091; 1,N,cPr,Cl,H,OCHF2], [AA4092; 1,N,cPr,Br,H,OCHF2], [AA4093; 1,N,cPr,I,H,OCHF2], [AA4094; 1,N,cPr,CF3,H,OCHF2], [AA4095; 1,N,cPr,CF2H,H,OCHF2], [AA4096; 1,N,cPr,C2F5,H,OCHF2], [AA4097; 1,N,cPr,C3F7,H,OCHF2], [AA4098; 1,N,cPr,CH2CF3,H,OCHF2], [AA4099; 1,N,cPr,CH2CHF2,H,OCHF2], [AA4100; 2,N,cPr,H,H,OCHF2], [AA4101; 2,N,cPr,F,H,OCHF2], [AA4102; 2,N,cPr,Cl,H,OCHF2], [AA4103; 2,N,cPr,Br,H,OCHF2], [AA4104; 2,N,cPr,I,H,OCHF2], [AA4105; 2,N,cPr,CF3,H,OCHF2], [AA4106; 2,N,cPr,CF2H,H,OCHF2], [AA4107; 2,N,cPr,C2F5,H,OCHF2], [AA4108; 2,N,cPr,C3F7,H,OCHF2], [AA4109; 2,N,cPr,CH2CF3,H,OCHF2], [AA4110; 2,N,cPr,CH2CHF2,H,OCHF2], [AA4111; 0,CH,H,H,F,OCHF2], [AA4112; 0,CH,H,H,Cl,OCHF2], [AA4113; 0,CH,H,H,Br,OCHF2], [AA4114; 0,CH,H,H,I,OCHF2], [AA4115; 0,CH,H,H,CF3,OCHF2], [AA4116;[0, CH, H, H, CF2H, OCHF2], [AA4117; 0, CH, H, H, C2F5, OCHF2], [AA4118; 0, CH, H, H, C3F7, OCHF2], [AA4119; 0, CH, H, H, CH2CF3, OCHF2], [AA4120; 0, CH, H, H, CH2CHF2, OCHF2], [AA4121; 1, CH, H, H, F, OCHF2], [AA4122; 1, CH, H, H, Cl, OCHF2], [AA4123; 1, CH, H, H, Br, OCHF2], [AA4124; 1, CH, H, H, I, OCHF2], [AA4125; 1, CH, H, H, CF3, OCHF2], [AA4126; 1, CH, H, H, CF2H, OCHF2]...
Claims
1. A compound represented by formula (I), In formula (I), R 2 represents ethyl n represents 2, G 1 represents CR 3a , G 2 represents CR 3b , G 3 represents CR 3c , G 4 represents CR 3d , R 3a and R 3d represent a hydrogen atom, R 3b and R 3c wherein one of them represents a hydrogen atom and the other represents a halogen atom or trifluoromethyl group, Q represents a group represented by Q2 or a group represented by Q3, ● represents the bonding position to the remainder of the molecule, Z represents an oxygen atom, A 4 represents a nitrogen atom, A 5 represents CH A 6 represents CH A 7 represents a nitrogen atom, B 1 、B 2 、B 3 and B 4 The combination of is: B 1 and B 2 and B 4 represents CH, B 3 represents a combination of C-CF3 or C-I; or B 1 and B 3 and B 4 represents CH, B 2 represents a combination of C-CF3 2. A pest arthropod control composition comprising the compound according to claim 1.
3. A composition comprising one or more components selected from group (a), group (b), group (c) and group (d), and the compound according to claim 1, Group (a): insecticidal active ingredient; Group (b): fungicidal active ingredient; Group (c): plant growth regulating ingredient; Group (d): repellent ingredient.
4. A method for controlling pest arthropods other than for the treatment of diseases, which comprises applying an effective amount of the compound according to claim 1 or an effective amount of the composition according to claim 3 to pest arthropods or their habitats.
5. A method for treating seeds or vegetative propagation organs, which comprises treating seeds or vegetative propagation organs with an effective amount of the compound according to claim 1 or an effective amount of the composition according to claim 3.
Citation Information
Patent Citations
DD10010A
DD10181A
DD10221A
DD10311A
DD10620A