A lower magnetic stirring device for bioreactor

Abstract

The application belongs to the technical field of magnetic stirring, and discloses a lower magnetic stirring device for a bioreactor, which comprises a bioreactor, a magnetic stirring base is welded at the bottom of the bioreactor, a supporting assembly is fixedly installed at the middle of the bottom of the inner cavity of the bioreactor, and a connecting assembly is placed at the top of the supporting assembly. When the water feeding assembly is driven to move by the magnetic assembly, the liquid in the magnetic assembly can be discharged outward, so that a negative pressure is formed in the magnetic assembly, liquid is supplemented from the outside through the opening in the middle of the magnetic rod, and due to the rotation of the cleaning stirring assembly, vortexes are formed, so that circulation is formed in the bioreactor, the liquid at the middle position is rotated downward and is sucked into the inside by the magnetic rod, then flows outward, and then moves upward along the inner wall of the bioreactor, and finally returns to the middle area at the top of the liquid, so that better stirring effect is achieved.

Description

Technical Field

[0001] This invention belongs to the field of magnetic stirring technology, specifically a magnetic stirring device for a bioreactor. Background Technology

[0002] A bioreactor is a reaction system that utilizes naturally occurring microorganisms or microorganisms with special degradation capabilities to inoculate a liquid or solid phase. A magnetic stirrer uses magnetic force to drive a stirring blade, thereby agitating materials. The drive unit and the stirring blade are two separate parts, allowing for non-contact rotation. This avoids the sealing, cleaning, and installation problems associated with mechanically driven stirrers, offering significant advantages.

[0003] In existing technologies, the magnetic stirring device used in bioreactors is located at the bottom of the bioreactor. During stirring, the liquid inside the reactor forms a vortex, which mixes the liquid with microorganisms. However, after the vortex is formed, the microorganisms are concentrated in the center of the vortex, which is not conducive to the reproduction of microorganisms. At the same time, in order to ensure the survival of microorganisms, oxygen needs to be introduced. The way it is introduced is to introduce it into the empty space inside the reactor. The oxygen mixes with the liquid slowly, which is not conducive to the reproduction of microorganisms. Therefore, improvements are needed. Summary of the Invention

[0004] (a) Technical problems to be solved

[0005] To address the problem mentioned in the background art that microorganisms tend to aggregate in the middle of the bottom of the reactor after stirring, which is detrimental to their reproduction, the present invention provides a magnetic stirring device for bioreactors.

[0006] (II) Technical Solution

[0007] To achieve the above objectives, the present invention provides the following technical solution: a magnetic stirring device for a bioreactor, comprising a bioreactor, a magnetic stirring base welded to the bottom of the bioreactor, a support assembly fixedly installed in the middle of the bottom of the bioreactor's inner cavity, a connecting assembly placed on top of the support assembly, a magnetic component fixedly installed in the middle of the connecting assembly, the magnetic stirring base driving the magnetic component to rotate clockwise or counterclockwise on the surface of the support assembly when the magnetic stirring base is activated, water supply components fixedly connected to both ends of the magnetic component, a gas input component fixedly installed on top of the magnetic component, movable components fixedly connected to both sides of the support assembly, and a [missing information - likely a component or component] fixedly installed in the middle of the movable component. The telescopic assembly has a cleaning and agitating component fixedly connected to the end of the movable assembly away from the supporting assembly. A limiting component is movably sleeved on the outer side of the upper end of the telescopic assembly. After the magnetic stirring base is activated, the magnetic assembly is rotated by magnetic force, causing it to rotate clockwise in the top view of the bioreactor. When the magnetic assembly drives the water delivery assembly, it can discharge the liquid inside the magnetic assembly, thereby creating a negative pressure inside the magnetic assembly. Liquid is then replenished from the outside through the opening in the middle of the magnetic rod. Simultaneously, the rotation of the magnetic assembly drives the gas input assembly to rotate, causing the first impeller to force the gas at the top into the connecting pipe. Under the negative pressure condition inside the magnetic assembly, the gas can enter the magnetic rod at a relatively low pressure. Inside the magnetic component, the cooperation of the guide plate and the separation plate mixes oxygen with the liquid, achieving a better oxygenation effect. Furthermore, the rotation of the magnetic component drives the connecting component to rotate synchronously. The connecting push plate, through a notch on its surface, engages with the positioning rod in the movable component during rotation, thereby driving the entire cleaning and agitating component to rotate, thus completing the stirring of the internal liquid. During stirring, the liquid enters through the middle of the magnetic component and exits through the middle of the water delivery component. The rotation of the cleaning and agitating component creates a vortex, forming a circulation within the bioreactor. The circulation direction is that the liquid in the middle position rotates downwards and is drawn into the interior by the magnetic rod, then flows outwards, and finally rises along the inner wall of the bioreactor. The liquid flows back to the middle area at the top; when the inside of the bioreactor needs to be cleaned, the magnetic stirring base can drive the magnetic component to rotate in the opposite direction. At this time, the other side of the connecting push plate with the notch forms a squeeze with the positioning rod, and drives the cleaning stirring component to rotate. Under the pressure of the connecting push plate and the centrifugal force of the rotating cleaning stirring component, the overall length of the moving component increases. The first corrugated pipe and the spring are compressed through the first connecting frame and the second connecting frame, so that the gas inside the first corrugated pipe enters the second corrugated pipe. The second corrugated pipe extends, which drives the overall length of the cleaning stirring component to increase. Simultaneously, the cleaning stirring component gradually approaches the inner wall of the bioreactor and finally contacts the inner wall of the bioreactor to form a scraping cleaning.

[0008] Preferably, the support assembly includes a fixed platform fixedly connected to the bioreactor, a first bearing fixedly installed in the middle of the fixed platform, a gear ring fixedly installed at the top outer end of the fixed platform, and the outer end of the first bearing fixedly connected to a movable component.

[0009] Preferably, the connecting assembly includes an annular component that contacts the top of the fixed platform. A third bearing is fixedly connected to the inner side of the annular component. Two connecting push plates are fixedly installed on both sides of the annular component near the fixed platform, which are distributed at equal angles in the circumferential direction of the fixed platform. The connecting push plates are rhomboid in shape and have a notch on one side of their outer end.

[0010] Preferably, the magnetic component includes a magnetic rod fixedly connected to a third bearing. A guide plate and a separation plate are symmetrically installed inside the magnetic rod from the inside to the outside. The guide plate is inclined from top to bottom towards the separation plate. A breaking hole is opened on the surface of the separation plate. A second bearing is fixedly installed at both ends of the magnetic rod.

[0011] Preferably, the gas input component includes a connecting pipe that is fixedly connected to the top of the magnetic rod, a one-way valve is fixedly installed at the bottom of the connecting pipe, the one-way valve can only pass through from top to bottom, a first impeller is fixedly installed at the upper end of the connecting pipe at an equal angle, the first impeller is fan-shaped, and the top of the connecting pipe is located above the liquid surface of the culture medium inside the bioreactor.

[0012] Preferably, the water delivery assembly includes a first toothed ring fixedly connected to the outer wheel of the second bearing, and a second impeller is fixedly installed inside the first toothed ring at equal angles, the second impeller being fan-shaped.

[0013] Preferably, the movable component includes a first connecting frame, a positioning rod is fixedly installed at the top end of the first connecting frame near the support component, a second connecting frame is movably sleeved at the lower end of the first connecting frame, the second connecting frame is fixedly connected to the outer wheel of the first bearing, and the first connecting frame is fixedly connected to the cleaning and agitating component.

[0014] Preferably, the telescopic component includes a first corrugated tube, a spring is movably sleeved on the outer surface of the first corrugated tube, one end of the first corrugated tube and the spring is fixedly connected to a first connecting frame and the other end is fixedly connected to a second connecting frame, the end of the first corrugated tube away from the support component is fixedly connected to the second corrugated tube through a connecting pipe, and the connecting pipe passes through the second connecting frame and extends into the interior of the cleaning agitator component.

[0015] Preferably, the limiting component includes a first sleeve, a second sleeve is movably sleeved at the upper end of the first sleeve, a third sleeve is movably sleeved at the upper end of the second sleeve, and the cleaning and agitating component is entirely wrapped around the outside of the second corrugated pipe.

[0016] Preferably, the cleaning agitation assembly includes a third agitation block, with a second agitation block movably sleeved on the upper end of the third agitation block, and a first agitation block movably sleeved on the upper end of the second agitation block. The first, second, and third agitation blocks are coplanar on the side closest to the inner wall of the bioreactor. The upper end of the bottom of the third agitation block is fixedly connected to the bottom of the first sleeve, and the lower end of the top of the first agitation block is fixedly connected to the top of the third sleeve. The third agitation block is fixedly connected to the second connecting frame.

[0017] (III) Beneficial Effects

[0018] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0019] 1. This invention utilizes a magnetic component that rotates clockwise from a top-down view of the inside of a bioreactor. When the magnetic component drives the water delivery component, it discharges the liquid inside the magnetic component, creating a negative pressure inside. Liquid is then replenished from the outside through the opening in the middle of the magnetic rod. Furthermore, the rotation of the magnetic component drives the connecting component to rotate synchronously. The connecting push plate engages with the positioning rod in the moving component through a notch on its surface, thereby driving the entire cleaning and stirring component to rotate, thus completing the stirring of the internal liquid. During the stirring process, the liquid enters through the middle of the magnetic component and is discharged outward through the middle of the water delivery component. The rotation of the cleaning and stirring component creates a vortex, forming a circulation inside the bioreactor. The circulation direction is that the liquid in the middle position rotates downward and is drawn into the interior by the magnetic rod, then flows outward, then upward along the inner wall of the bioreactor, and finally flows back to the middle area at the top of the liquid, achieving a better stirring effect.

[0020] 2. This invention utilizes a magnetic component that rotates clockwise from a top-down view of the bioreactor's interior. When the magnetic component drives the water delivery component, it discharges liquid from inside the component, creating a negative pressure. Liquid is then replenished from the outside through the opening in the middle of the magnetic rod. Simultaneously, the rotation of the magnetic component drives the gas input component, causing the first impeller to force gas from the top into the connecting pipe. Under the negative pressure inside the magnetic component, gas can enter with relatively low pressure. Through the cooperation of the guide plate and separation plate, oxygen mixes with the liquid, achieving a better oxygenation effect.

[0021] 3. In this invention, the magnetic stirring base drives the magnetic component to rotate in the opposite direction. At this time, the other side of the connecting push plate with the notch forms a compression with the positioning rod, and drives the cleaning and stirring component to rotate. Under the pressure of the connecting push plate and the centrifugal force of the rotating cleaning and stirring component, the overall length of the moving component increases. The first corrugated pipe and the spring are compressed by the first connecting frame and the second connecting frame, so that the gas inside the first corrugated pipe enters the second corrugated pipe. The second corrugated pipe elongates, which drives the overall length of the cleaning and stirring component to increase. Simultaneously, the cleaning and stirring component gradually approaches the inner wall of the bioreactor and finally contacts the inner wall of the bioreactor to form a scraping cleaning. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of the present invention;

[0023] Figure 2 This is a schematic diagram of the internal structure of the bioreactor of the present invention;

[0024] Figure 3 This is a schematic diagram of the structure of the support component of the present invention;

[0025] Figure 4 This is a structural separation diagram of the gas input component of the present invention;

[0026] Figure 5 This is a partial cross-sectional view of the structure at the gas input component of the present invention;

[0027] Figure 6 This is a cross-sectional view of the structure at the magnetic rod of the present invention;

[0028] Figure 7 This is a structural separation diagram of the water delivery component of the present invention;

[0029] Figure 8 This is a structural separation diagram of the cleaning and stirring component of the present invention;

[0030] Figure 9 This is a structural separation diagram of the active component of the present invention.

[0031] In the diagram: 1. Bioreactor; 2. Magnetic stirring base; 3. Support assembly; 31. Fixing platform; 32. First bearing; 33. Gear ring; 4. Magnetic assembly; 41. Magnetic rod; 42. Guide plate; 43. Separation plate; 44. Second bearing; 5. Gas input assembly; 51. Connecting pipe; 52. One-way valve; 53. First impeller; 6. Water supply assembly; 61. First gear ring; 62. Second impeller; 7. Connecting assembly; 71. Third bearing 72. Ring-shaped component; 73. Connecting push plate; 8. Movable component; 81. First connecting frame; 82. Positioning rod; 83. Second connecting frame; 9. Telescopic component; 91. First bellows; 92. Spring; 93. Second bellows; 10. Limiting component; 101. First sleeve; 102. Second sleeve; 103. Third sleeve; 11. Cleaning agitator component; 111. First agitator block; 112. Second agitator block; 113. Third agitator block. Detailed Implementation

[0032] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0033] like Figures 1 to 9 As shown, the present invention provides a magnetic stirring device for a bioreactor, including a bioreactor 1, a magnetic stirring base 2 welded to the bottom of the bioreactor 1, a support component 3 fixedly installed in the middle of the bottom of the inner cavity of the bioreactor 1, a connecting component 7 placed on the top of the support component 3, a magnetic component 4 fixedly installed in the middle of the connecting component 7, when the magnetic stirring base 2 is started, it can drive the magnetic component 4 to rotate clockwise or counterclockwise on the surface of the support component 3, a water supply component 6 fixedly connected to both ends of the magnetic component 4, a gas input component 5 fixedly installed on the top of the magnetic component 4, movable components 8 fixedly connected to both sides of the support component 3, a telescopic component 9 fixedly installed in the middle of the movable component 8, a cleaning and stirring component 11 fixedly connected to the end of the movable component 8 away from the support component 3, and a limit component 10 movably sleeved on the outer side of the upper end of the telescopic component 9.

[0034] like Figure 4 , Figure 6 , Figure 7As shown, the support assembly 3 includes a fixed platform 31 fixedly connected to the bioreactor 1. A first bearing 32 is fixedly installed in the middle of the fixed platform 31, and a gear ring 33 is fixedly installed at the top outer end of the fixed platform 31. The outer end of the first bearing 32 is fixedly connected to the movable assembly 8. The connecting assembly 7 includes an annular member 72 that contacts the top of the fixed platform 31. A third bearing 71 is fixedly connected to the inner side of the annular member 72. Two connecting push plates 73 are fixedly installed on both sides of the annular member 72 near the fixed platform 31, which are distributed at equal angles in a ring in the circumferential direction of the fixed platform 31. The shape of the connecting push plates 73 is... The magnetic component 4 is rhomboid in shape with a notch on one side of the outer end. It includes a magnetic rod 41 fixedly connected to the third bearing 71. Inside the magnetic rod 41, a guide plate 42 and a separation plate 43 are symmetrically installed from the inside to the outside. The guide plate 42 is inclined from top to bottom and points towards the separation plate 43. The surface of the separation plate 43 is provided with a breaking hole. The two ends of the magnetic rod 41 are fixedly installed with the second bearing 44. The water delivery component 6 includes a first toothed ring 61 fixedly connected to the outer wheel of the second bearing 44. Inside the first toothed ring 61, a second impeller 62 is fixedly installed at an equal angle. The second impeller 62 is fan-shaped.

[0035] The above scheme is adopted because the magnetic component 4 is attracted by the magnetic stirring base 2, and the magnetic force is strong enough. This ensures that the water delivery component 6 and the gear ring 33 will not derail when the magnetic stirring base 2 drives the magnetic component 4 to rotate, thus ensuring the rationality of the structure. The magnetic stirring base 2 drives the magnetic component 4 to rotate in both directions by magnetic force, which is existing technology, so its principle will not be introduced. The design of the connecting push plate 73 is to limit and squeeze the positioning rod 82, and to ensure the stability of the magnetic component 4 when it rotates, preventing the magnetic component 4 from rotating on its own, and ensuring the stability of the position of the gas input component 5 at the top of the magnetic rod 41. When the external oxygen and the liquid inside the bioreactor 1 enter the magnetic rod 41 through the middle of the gas input component 5, the gas and liquid mix, and the uniformity of the mixing is further ensured by the action of the guide plate 42 and the separation plate 43, thus ensuring the effect of use.

[0036] like Figure 5 As shown, the gas input component 5 includes a connecting pipe 51 that is fixedly connected to the top of the magnetic rod 41. A one-way valve 52 is fixedly installed at the bottom of the connecting pipe 51. The one-way valve 52 can only pass through from top to bottom. A first impeller 53 is fixedly installed at the upper end of the connecting pipe 51 at an annular angle. The first impeller 53 is fan-shaped. The top of the connecting pipe 51 is located above the liquid surface of the culture medium inside the bioreactor 1.

[0037] The above solution ensures oxygen can enter only when the connecting pipe 51 extends to the top of the liquid surface. In conventional oxygenation methods, the oxygen and liquid mix slowly. The one-way valve 52 prevents liquid from flowing back into the connecting pipe 51 through the magnetic rod 41, thus ensuring the stability of the structure.

[0038] like Figure 9 As shown, the active component 8 includes a first connecting frame 81, a positioning rod 82 is fixedly installed at the top end of the first connecting frame 81 near the support component 3, a second connecting frame 83 is movably sleeved at the lower end of the first connecting frame 81, the second connecting frame 83 is fixedly connected to the outer wheel of the first bearing 32, and the first connecting frame 81 is fixedly connected to the cleaning and agitating component 11.

[0039] The above scheme is adopted: the positioning rod 82 can cooperate with the connecting push plate 73, so that when the connecting push plate 73 rotates, it drives the positioning rod 82 to move. When the magnetic component 4 rotates clockwise in the top view inside the bioreactor 1, the notch on the surface of the connecting push plate 73 can limit the positioning rod 82 to prevent the overall length of the moving component 8 from changing. At this time, when the cleaning and stirring component 11 rotates, there is no friction when it contacts the inner wall of the bioreactor 1, and the rotation speed is relatively fast, ensuring the stirring effect. When the magnetic component 4 rotates counterclockwise, the connecting push plate 73 squeezes the positioning rod 82 through the inclined surface. Through pressure and centrifugal force, the cleaning and stirring component 11 contacts the inner wall of the bioreactor 1 and cleans by scraping. At this time, the rotation speed is relatively slow.

[0040] like Figure 8 As shown, the telescopic component 9 includes a first bellows 91, and a spring 92 is movably sleeved on the outer surface of the first bellows 91. One end of the first bellows 91 and the spring 92 are fixedly connected to the first connecting frame 81, and the other end is fixedly connected to the second connecting frame 83. The end of the first bellows 91 away from the support component 3 is fixedly connected to the second bellows 93 through a connecting pipe. The connecting pipe passes through the second connecting frame 83 and extends into the interior of the cleaning agitator component 11.

[0041] The above scheme is adopted: when the overall length of the active component 8 increases, the first bellows 91 and the spring 92 are compressed, the air inside the first bellows 91 is squeezed into the second bellows 93, the length of the second bellows 93 increases, thereby adjusting the overall length of the cleaning agitation component 11 and the cleaning range is wider.

[0042] like Figure 8 As shown, the limiting component 10 includes a first sleeve 101, a second sleeve 102 is movably sleeved at the upper end of the first sleeve 101, a third sleeve 103 is movably sleeved at the upper end of the second sleeve 102, and the cleaning and agitating component 11 is entirely wrapped around the outside of the second corrugated pipe 93.

[0043] The above solution is adopted: the limiting component 10 is fitted on the outside of the second corrugated pipe 93, and the second corrugated pipe 93 is limited when it expands or contracts to ensure stability.

[0044] like Figure 8 As shown, the cleaning agitation assembly 11 includes a third agitation block 113, a second agitation block 112 is movably sleeved on the upper end of the third agitation block 113, a first agitation block 111 is movably sleeved on the upper end of the second agitation block 112, the first agitation block 111, the second agitation block 112, and the third agitation block 113 are coplanar on the side near the inner wall of the bioreactor 1, the upper end of the bottom of the third agitation block 113 is fixedly connected to the bottom of the first sleeve 101, the lower end of the top of the first agitation block 111 is fixedly connected to the top of the third sleeve 103, and the third agitation block 113 is fixedly connected to the second connecting frame 83.

[0045] The above scheme is adopted: the first stirring block 111, the second stirring block 112 and the third stirring block 113 are coplanar on the side near the inner wall of the bioreactor 1. This ensures that the elongated cleaning stirring component 11 can achieve a good scraping effect even when the overall length of the cleaning stirring component 11 is increased.

[0046] Working principle and usage process of this invention:

[0047] In use, activating the magnetic stirring base 2 drives the magnetic component 4 to rotate. Simultaneously, the magnetic stirring base 2 magnetically attracts the magnetic component 4 to the top of the support component 3. As the magnetic component 4 rotates clockwise inside the bioreactor 1 (from a top-down view), it drives the water delivery component 6 to move along the surface of the gear ring 33. The first gear ring 61, in conjunction with the second impeller 62, discharges the liquid inside the magnetic rod 41, creating a negative pressure inside the magnetic rod 41. This negative pressure then draws liquid into the outside through the center of the magnetic rod 41. Simultaneously, due to the negative pressure and the rotation of the gas input component 5, external gas is forced into the connection... Inside the pipe 51, the gas inside the connecting pipe 51 can be input into the magnetic rod 41 through the one-way valve 52, and move towards the water delivery assembly 6 inside the magnetic rod 41. During the movement, it comes into contact with the guide plate 42 and the separation plate 43 in turn, so that the oxygen in the gas mixes more thoroughly with the liquid. Simultaneously, when the magnetic assembly 4 rotates, it also drives the connecting assembly 7 to rotate. When the connecting push plate 73 rotates, it locks the positioning rod 82 through the notch on its surface, thereby driving the positioning rod 82 to rotate, and then driving the entire cleaning agitator 11 to rotate. While mixing oxygen, it can also make the liquid more thoroughly stirred.

[0048] When the magnetic component 4 rotates counterclockwise in a top-down view inside the bioreactor 1, the connecting push plate 73 presses against the positioning rod 82. Since the outer edge of the connecting push plate 73 is inclined, the positioning rod 82 can move outward under the thrust. Although the movable component 8 is connected to the fixed platform 31 via the first bearing 32, the movable component 8 is entirely connected to the cleaning and agitating component 11. The resistance of the cleaning and agitating component 11 moving within the liquid counteracts the thrust of the connecting push plate 73 against the positioning rod 82, thus enabling the positioning rod 82 to be pushed outward. When the positioning rod 82 moves outward, it squeezes the first bellows 91 and the spring 92 through the first connecting frame 81 and the second connecting frame 83, causing the gas inside the first bellows 91 to enter the second bellows 93, thereby increasing the overall length of the second bellows 93, and thus increasing the overall length of the cleaning agitator 11, which can clean more areas. Under the centrifugal force of the cleaning agitator 11 when it rotates and the pushing force of the connecting push plate 73 on the positioning rod 82, the cleaning agitator 11 can contact the inner wall of the bioreactor 1.

[0049] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0050] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A magnetic stirring device for a bioreactor, comprising a bioreactor (1), wherein a magnetic stirring base (2) is welded to the bottom of the bioreactor (1), characterized in that: A support assembly (3) is fixedly installed in the middle of the bottom of the bioreactor (1). A connecting assembly (7) is placed on the top of the support assembly (3). A magnetic assembly (4) is fixedly installed in the middle of the connecting assembly (7). When the magnetic stirring base (2) is started, it can drive the magnetic assembly (4) to rotate clockwise or counterclockwise on the surface of the support assembly (3). A water delivery assembly (6) is fixedly connected to both ends of the magnetic assembly (4). A gas input assembly (5) is fixedly installed on the top of the magnetic assembly (4). Movable assemblies (8) are fixedly connected to both sides of the support assembly (3). A telescopic assembly (9) is fixedly installed in the middle of the movable assembly (8). A cleaning agitator assembly (11) is fixedly connected to the end of the movable assembly (8) away from the support assembly (3). A limit assembly (10) is movably sleeved on the outer side of the upper end of the telescopic assembly (9). The support assembly (3) includes a fixed platform (31) fixedly connected to the bioreactor (1). A first bearing (32) is fixedly installed in the middle of the fixed platform (31). A gear ring (33) is fixedly installed at the top outer end of the fixed platform (31). The outer end of the first bearing (32) is fixedly connected to the movable assembly (8). The connecting assembly (7) includes an annular part (72) that contacts the top of the fixed platform (31). A third bearing (71) is fixedly connected to the inner side of the annular part (72). Two connecting push plates (73) are fixedly installed on both sides of the annular part (72) near the fixed platform (31) and are distributed at equal angles in the circumferential direction of the fixed platform (31). The connecting push plates (73) are rhomboid in shape and have a notch on one side of the outer end. The magnetic component (4) includes a magnetic rod (41) fixedly connected to a third bearing (71), and a second bearing (44) is fixedly installed at both ends of the magnetic rod (41). The water delivery assembly (6) includes a first toothed ring (61) fixedly connected to the outer wheel of the second bearing (44), and a second impeller (62) is fixedly installed inside the first toothed ring (61) at equal angles. The second impeller (62) is fan-shaped. The active component (8) includes a first connecting frame (81), a positioning rod (82) is fixedly installed at the top of the first connecting frame (81) near the support component (3), a second connecting frame (83) is movably sleeved at the lower end of the first connecting frame (81), the second connecting frame (83) is fixedly connected to the outer wheel of the first bearing (32), and the first connecting frame (81) is fixedly connected to the cleaning agitation component (11); The telescopic component (9) includes a first bellows (91), and a spring (92) is movably sleeved on the outer surface of the first bellows (91). One end of the first bellows (91) and the spring (92) are fixedly connected to the first connecting frame (81), and the other end is fixedly connected to the second connecting frame (83). The end of the first bellows (91) away from the support component (3) is fixedly connected to the second bellows (93) through a connecting pipe. The connecting pipe passes through the second connecting frame (83) and extends into the interior of the cleaning agitation component (11). The cleaning agitation assembly (11) is entirely wrapped around the outside of the second bellows (93).

2. The magnetic stirring device for a bioreactor according to claim 1, characterized in that: Inside the magnetic rod (41), a guide plate (42) and a separation plate (43) are symmetrically installed from the inside to the outside. The guide plate (42) is inclined from top to bottom towards the separation plate (43), and the surface of the separation plate (43) is provided with a breaking hole.

3. The magnetic stirring device for a bioreactor according to claim 2, characterized in that: The gas input component (5) includes a connecting pipe (51) that is fixedly connected to the top of the magnetic rod (41). A one-way valve (52) is fixedly installed at the bottom of the connecting pipe (51). The one-way valve (52) can only pass through from top to bottom. A first impeller (53) is fixedly installed at the upper end of the connecting pipe (51) at an equal angle. The first impeller (53) is fan-shaped. The top of the connecting pipe (51) is located above the liquid surface of the culture medium inside the bioreactor (1).

4. The magnetic stirring device for a bioreactor according to claim 1, characterized in that: The limiting component (10) includes a first sleeve (101), the upper end of the first sleeve (101) is movably sleeved with a second sleeve (102), and the upper end of the second sleeve (102) is movably sleeved with a third sleeve (103).

5. The magnetic stirring device for a bioreactor according to claim 4, characterized in that: The cleaning agitation assembly (11) includes a third agitation block (113), the upper end of which is movably sleeved with a second agitation block (112), the upper end of which is movably sleeved with a first agitation block (111), the first agitation block (111), the second agitation block (112), and the third agitation block (113) are coplanar on the side near the inner wall of the bioreactor (1), the upper end of the bottom of the third agitation block (113) is fixedly connected to the bottom of the first sleeve (101), the lower end of the top of the first agitation block (111) is fixedly connected to the top of the third sleeve (103), and the third agitation block (113) is fixedly connected to the second connecting frame (83).

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