A double-headed granule filling device for preparing oseltamivir phosphate dry suspension

Abstract

The present invention discloses a double-head granule filling device for preparing oseltamivir phosphate dry suspension, which relates to the field of processing oseltamivir phosphate dry suspension. A double-head granule filling device includes a workbench, a conveyor belt arranged on the workbench, and a double-head filling unit arranged on the top of the workbench. A detection unit is arranged at the bottom of the double-head filling unit, and a plurality of packaging cans are arranged on the conveyor belt. An installation box is fixedly installed on the top of the workbench, and a calibration mechanism is arranged on the installation box; for this double-head granule filling device for preparing oseltamivir phosphate dry suspension, the driving component drives the cross plate to rotate, so that the arc-shaped support plate arranged on the limiting baffle can clamp the packaging can and drive it to move upward to be separated from the conveyor belt, so that when the conveyor belt conveys the subsequent packaging cans forward, it will not affect the position of the current packaging can, enabling all packaging cans to be filled and then conveyed forward, thereby effectively reducing the probability of filling omission.

Description

Technical Field

[0001] The present invention relates to the processing technology of oseltamivir phosphate for dry suspension, and more particularly to a double-head granule filling device for preparing oseltamivir phosphate for dry suspension. Background Art

[0002] The chemical name of oseltamivir phosphate is (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester, and its Chemical Substance Registration Number CASRN is 196618-13-0.

[0003] After oral administration, oseltamivir is rapidly catalyzed and converted into its active metabolite oseltamivir carboxylate by liver and intestinal esterases. The configuration of oseltamivir carboxylate is similar to the transition state of neuraminic acid, and it can competitively bind to the active site of influenza virus neuraminidase (NA, also known as neuraminidase), so it is a potent and highly selective influenza virus NA inhibitor (NAIs). It mainly reduces the transmission of influenza A or B viruses by interfering with the release of the virus from infected host cells. Currently, the marketed dosage forms of oseltamivir phosphate include granules, capsules, dry suspensions, etc.

[0004] When granulated oseltamivir phosphate is packaged, it is usually filled by a double-head granule filling device. When the existing double-head granule filling device works, the packaging cans are transported by a conveyor belt, and two telescopic filling pipes are used to simultaneously fill two packaging cans synchronously. In order to prevent the occurrence of leakage of the bottles and the spilling of granules on the conveyor belt, the existing filling device will detect the packaging cans before filling. When there is a leakage or no bottle at the rear, the filling operation will not be carried out. Although this operation method can effectively prevent the spilling of oseltamivir phosphate granules, for the front packaging cans, when the conveyor belt continues to transport the rear packaging cans forward, the front packaging cans will also be transported forward, resulting in the situation of missed filling of the packaging cans. Summary of the Invention

[0005] The purpose of the present invention is to provide a double-head granule filling device for preparing oseltamivir phosphate for dry suspension to solve the above deficiencies in the prior art.

[0006] To achieve the above object, the present invention provides the following technical solution: A double-head granule filling device, including a workbench, a conveyor belt provided on the workbench, and a double-head filling unit provided on the top of the workbench. A detection unit is provided at the bottom of the double-head filling unit. A PLC controller is also provided on the workbench. Under normal working conditions, the PLC controller controls the work of the conveyor belt, the double-head filling unit, and the detection unit. The above double-head filling unit includes a telescopic filling pipe and a feeding unit. Granules are sent into the telescopic pipe through the feeding unit, and then the telescopic filling pipe extends downward to sleeved on the port part of the packaging can and fills the granules into it. Moreover, the one-time conveying distance of the conveyor belt is fixedly set, and this distance value corresponds to the size values of two packaging cans. At the end of one-time conveying, the telescopic filling pipe extends downward and sleeved on the top of the packaging can. Before filling, the detection unit at the bottom of the telescopic filling pipe detects the packaging can below. When there is no packaging can under the telescopic filling pipe on the side away from the packaging can, the PLC controller will control the conveyor belt to perform a feeding action of half of the distance. When there is no packaging can under the telescopic filling pipe on the side close to the packaging can, the double-head filling unit will not perform the filling operation. The above mechanism and control principle process are all prior arts in existing production equipment and will not be elaborated here. A number of packaging cans are provided on the conveyor belt. An installation box is fixedly installed on the top of the workbench, and a correction mechanism is provided on the installation box;

[0007] The correction mechanism includes a movable cavity opened inside the installation box. A cross plate is rotatably connected to the inner side surface of the movable cavity. A driving component is provided outside the cross plate. A limiting baffle is provided at the bottom of the cross plate. Two symmetrical arc-shaped supporting plates are provided outside the limiting baffle. An auxiliary component is provided outside the arc-shaped supporting plate. Infrared sensors are embedded on the surface of the arc-shaped supporting plate.

[0008] Further, the driving component includes a motor one fixedly installed inside the movable cavity. A worm is fixedly connected to the outside of the output shaft of the motor one. A worm gear is meshed and connected to the outside of the worm. The worm gear is coaxially fixedly connected to the cross plate. Utilizing the self-locking characteristic between the worm and the worm gear, when the cross plate blocks the conveying of the packaging can, it will not rotate reversely under the thrust of the packaging can, so that its working stability is better.

[0009] Further, the auxiliary component includes a cavity opened at the bottom of the cross plate. An electric cylinder is fixedly connected inside the cavity. The bottom of the telescopic end of the electric cylinder is fixedly connected to the limiting baffle.

[0010] Further, the auxiliary component further includes a guiding groove formed on the surface of the limiting baffle. A bidirectional screw is rotatably connected to the inner side surface of the guiding groove. Two guiding blocks are threadedly connected to the outer part of the bidirectional screw. A sliding groove is formed on the inner side surface of the guiding block. The arc-shaped supporting plate is slidably connected to the inner side surface of the sliding groove. A first spring damper is fixedly connected between one side of the sliding groove away from the other guiding block and the arc-shaped supporting plate. When the packaging can moves to be blocked by the arc-shaped supporting plate, the packaging can can be clamped by the arc-shaped supporting plates on both sides, and the telescopic end of the electric cylinder contracts to drive the packaging can to move upward and separate from the surface of the conveyor belt. When the conveyor belt continues to supply materials, the continuous conveying of the conveyor belt will not drive the packaging can to move forward continuously, nor will the packaging can slide vertically along the surface of the limiting baffle under the blocking action of the limiting baffle, so that the position of the packaging can will not shift. Moreover, the packaging can will not have a relatively intense relative friction movement with the surface of the conveyor belt.

[0011] Further, the two guiding blocks are symmetrically arranged on both sides of the bidirectional screw. A second motor is arranged inside the limiting baffle. The output shaft of the second motor is fixedly connected to the bidirectional screw. When the bidirectional screw rotates, the two guiding blocks move synchronously and in opposite directions.

[0012] Further, the arc-shaped supporting plate includes a limiting part and a clamping part. Through the limiting part of the arc-shaped supporting plate, the continuous movement of the packaging can can be restricted when the packaging can moves into the inside of the arc-shaped supporting plate. And through the clamping part, the packaging can can be clamped and fixed when needed. In addition, in the non-clamping state, the distance value between adjacent two limiting parts is smaller than the maximum bottle diameter value of the packaging can, and the distance value between adjacent two clamping parts is larger than the maximum bottle diameter value of the packaging can.

[0013] Further, a control mechanism is arranged on the arc-shaped supporting plate. The control mechanism includes a movable groove formed inside the arc-shaped supporting plate. A second spring damper is fixedly connected to the inside of the movable groove. A connecting frame is fixedly connected to the outside of the second spring damper. A rubber wheel is rotatably connected to the inner side surface of the connecting frame. The end of the rubber wheel extends to the outside of the arc-shaped supporting plate. A torsion spring is arranged between the rubber wheel and the connecting frame.

[0014] Further, the control mechanism further includes a gear rotatably connected to the surface of the connecting frame. A limiting groove is formed inside the connecting frame. A guiding plate is slidably connected to the inner side surface of the limiting groove. A rack is fixedly connected to the outside of the guiding plate. A pressing button is arranged inside the movable groove. Under the limiting and guiding action of the limiting groove, the guiding plate can only slide linearly along the inner side surface of the limiting groove.

[0015] Further, the gear meshes with the rack, and the pressing button is electrically connected to the first motor. After the pressing button is pressed, the PLC controller first controls the second motor to drive the bidirectional screw to rotate reversely, and then controls the first motor to drive the worm to rotate reversely.

[0016] A double-headed granule filling device for preparing oseltamivir phosphate dry suspension, including the above-mentioned double-headed granule filling device, and this double-headed granule filling device for preparing oseltamivir phosphate dry suspension is used to prepare oseltamivir phosphate dry suspension;

[0017] It further includes two calibration plates fixedly installed on the workbench, and the two calibration plates are symmetrically arranged on both sides above the conveyor belt.

[0018] Compared with the prior art, a double-headed granule filling device for preparing oseltamivir phosphate dry suspension provided by the present invention has the following beneficial effects:

[0019] 1. For this double-headed granule filling device for preparing oseltamivir phosphate dry suspension, by driving the cross plate to rotate through the driving component, the arc-shaped support plate arranged on the limiting baffle can clamp the packaging can and drive it to move upward to separate from the conveyor belt, so that when the conveyor belt conveys the subsequent packaging cans forward, it will not affect the position of the current packaging can, enabling all packaging cans to be filled and then conveyed forward, thereby effectively reducing the probability of filling omission.

[0020] 2. For this double-headed granule filling device for preparing oseltamivir phosphate dry suspension, when the clamped packaging can moves downward under the downward thrust, it drives the rubber wheel to rotate, causing the gear to rotate accordingly and driving the rack to move upward, enabling the rack to move and press the pressing button, so that during the granule filling process of the packaging can, it can control the arc-shaped support plate to release the clamping of the packaging can and rotate reversely to move back to its original position, thus facilitating the continuous forward conveyance of the filled packaging cans. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments recorded in the present invention, and those of ordinary skill in the art can also obtain other drawings based on these drawings.

[0022] Figure 1 It is the overall structural schematic diagram provided by the embodiment of the present invention;

[0023] Figure 2 It is the structural schematic diagram of the calibration mechanism in the working state provided by the embodiment of the present invention;

[0024] Figure 3 Provided by the embodiment of the present inventionFigure 2 Schematic enlarged structure diagram at position A in

[0025] Figure 4 Schematic structure diagram of the calibration mechanism in the non - working state provided by an embodiment of the present invention;

[0026] Figure 5 Schematic internal structure diagram of the installation box provided by an embodiment of the present invention;

[0027] Figure 6 Schematic internal structure diagram of the cross - plate and the limiting baffle provided by an embodiment of the present invention;

[0028] Figure 7 Provided by an embodiment of the present invention Figure 6 Schematic enlarged structure diagram at position B in

[0029] Figure 8 Schematic internal structure diagram of the arc - shaped support plate provided by an embodiment of the present invention;

[0030] Figure 9 Provided by an embodiment of the present invention Figure 8 Schematic enlarged structure diagram at position C in

[0031] Explanation of reference numerals:

[0032] 1, workbench; 2, conveyor belt; 3, double - head filling unit; 4, packaging can; 5, installation box; 6, calibration mechanism; 61, cross - plate; 62, drive assembly; 621, motor 1; 622, worm; 623, worm gear; 63, limiting baffle; 64, arc - shaped support plate; 641, limiting part; 642, clamping part; 65, auxiliary assembly; 651, guide groove; 652, bidirectional screw; 653, guide block; 654, chute; 655, first spring damper; 656, cavity; 657, electric cylinder; 66, infrared sensor; 7, control mechanism; 71, second spring damper; 72, connecting frame; 73, rubber wheel; 74, torsion spring; 75, gear; 76, guide plate; 77, rack; 78, pressing button; 79, limiting groove; 8, calibration plate. Detailed implementation manners

[0033] In order to enable those skilled in the art to better understand the technical solutions of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0034] Embodiment 1:

[0035] Please refer to Figures 1-9, A double-headed granule filling device, including a workbench 1, a conveyor belt 2 arranged on the workbench 1, and a double-headed filling unit 3 arranged on the top of the workbench 1. A detection unit is arranged at the bottom of the double-headed filling unit 3. A PLC controller is also arranged on the workbench 1. Under normal working conditions, the work of the conveyor belt 2, the double-headed filling unit 3, and the detection unit is controlled by the PLC controller. The above double-headed filling unit 3 includes a telescopic filling pipe and a feeding unit. Granules are fed into the telescopic pipe through the feeding unit, and then the telescopic filling pipe extends downward to sleeve on the port part of the packaging can 4 and feed the granules into it. Moreover, the one-time conveying distance of the conveyor belt 2 is fixedly set, and this distance value corresponds to the size values of the two packaging cans 4. At the end of one-time conveying, the telescopic filling pipe extends downward and sleeves on the top of the packaging can 4. Before filling, the telescopic filling pipe uses the detection unit at its bottom to detect the packaging can 4 below. When there is no packaging can 4 under the telescopic filling pipe on the side away from the packaging can 4, the PLC controller will control the conveyor belt 2 to perform a feeding action of half of the distance. When there is no packaging can 4 under the telescopic filling pipe on the side close to the packaging can 4, the double-headed filling unit 3 will not perform the filling operation. The above mechanism and control principle process are all prior arts in existing production equipment and will not be elaborated here. There are several packaging cans 4 on the conveyor belt 2. An installation box 5 is fixedly installed on the top of the workbench 1. A calibration mechanism 6 is arranged on the installation box 5. When there is no packaging can 4 under the telescopic filling pipe on the side close to the packaging can 4, the double-headed filling unit 3 will not perform the filling operation. Through setting the control of the PLC controller, in this case, the PLC controller controls the conveyor belt 2 to perform a feeding action of half of the distance, so that it can cooperate with the calibration mechanism 6 to perform filling treatment on all packaging cans 4;

[0036] The calibration mechanism 6 includes a movable cavity opened inside the installation box 5. A cross plate 61 is rotatably connected to the inner side surface of the movable cavity. A driving component 62 is arranged outside the cross plate 61. A limiting baffle 63 is arranged at the bottom of the cross plate 61. Two symmetric arc-shaped supporting plates 64 are arranged outside the limiting baffle 63. An auxiliary component 65 is arranged outside the arc-shaped supporting plates 64. An infrared sensor 66 is embedded on the surface of the arc-shaped supporting plates 64, and the infrared sensor 66 is electrically connected to the PLC controller. The infrared sensor 66 includes an infrared emitting end and an infrared receiving end, which are respectively arranged inside the two arc-shaped supporting plates 64 and are in corresponding positions. When the packaging can 4 moves into the space between the two arc-shaped supporting plates 64, the PLC controller controls the second motor to drive the bidirectional screw 652 to rotate, so that the two arc-shaped supporting plates 64 approach each other under the driving force to clamp and fix the packaging can 4.

[0037] In this embodiment, the driving assembly 62 includes a first motor 621 fixedly installed inside the movable cavity. An external portion of the output shaft of the first motor 621 is fixedly connected with a worm 622. The external portion of the worm 622 is meshed and connected with a worm gear 623. The worm gear 623 is coaxially and fixedly connected with the cross plate 61. By utilizing the self-locking characteristic between the worm 622 and the worm gear 623, when the cross plate 61 blocks the conveyance of the packaging cans 4, it will not rotate reversely under the thrust of the packaging cans 4, thereby making its working stability better;

[0038] Under the driving action of the driving assembly 62, the cross plate 61 has two states:

[0039] Non-working state: At this time, the cross plate 61 is parallel to the conveyance direction of the conveyor belt 2 and will not restrict the movement of the packaging cans 4. At the same time, in this state, the telescopic end of the electric cylinder 657 is in the downward extended state;

[0040] Working state: At this time, the cross plate 61 rotates to be perpendicular to the conveyance direction of the conveyor belt 2 and can block the continuous forward movement of the packaging cans 4. At the same time, in this state, the telescopic end of the electric cylinder 657 is in the upward retracted state.

[0041] In the working state, when the cross plate 61 rotates to be perpendicular to the conveyance direction of the conveyor belt 2, the position of the arc-shaped support plate 64 corresponds to the packaging cans 4 that are about to be conveyed forward but not filled yet. At this time, when the two arc-shaped support plates 64 approach each other, they can stably clamp and fix the packaging cans 4.

[0042] The auxiliary assembly 65 includes a cavity 656 opened at the bottom of the cross plate 61. An electric cylinder 657 is fixedly connected inside the cavity 656. The bottom of the telescopic end of the electric cylinder 657 is fixedly connected with the limiting baffle 63.

[0043] The auxiliary component 65 further includes a guiding groove 651 formed on the surface of the limiting baffle 63. A bidirectional screw 652 is rotatably connected to the inner side surface of the guiding groove 651. Two guiding blocks 653 are threadedly connected to the outside of the bidirectional screw 652. A sliding groove 654 is formed on the inner side surface of the guiding block 653. The arc-shaped supporting plate 64 is slidably connected to the inner side surface of the sliding groove 654. A first spring damper 655 is fixedly connected between one side of the sliding groove 654 away from the other guiding block 653 and the arc-shaped supporting plate 64. When the packaging can 4 moves to be blocked by the arc-shaped supporting plate 64, the packaging can 4 can be clamped by the two arc-shaped supporting plates 64 on both sides. The telescopic end of the electric cylinder 657 contracts to drive the packaging can 4 to move upward and separate from the surface of the conveyor belt 2. When the conveyor belt 2 continues to supply materials, the continuous conveying of the conveyor belt 2 will not drive the packaging can 4 to move forward continuously, nor will the packaging can 4 slide vertically along the surface of the limiting baffle 63 in the conveying direction of the packaging can 4 under the blocking action of the limiting baffle 63, so that the position of the packaging can 4 will not shift. Moreover, the packaging can 4 will not have a relatively intense relative friction movement with the surface of the conveyor belt 2.

[0044] The two guiding blocks 653 are symmetrically arranged on both sides of the bidirectional screw 652. A second motor is arranged inside the limiting baffle 63. The output shaft of the second motor is fixedly connected to the bidirectional screw 652. When the bidirectional screw 652 rotates, the two guiding blocks 653 move synchronously and in opposite directions.

[0045] In this embodiment, the arc-shaped supporting plate 64 includes a limiting portion 641 and a clamping portion 642. Through the limiting portion 641 of the arc-shaped supporting plate 64, the continuous movement of the packaging can 4 can be restricted when it moves into the inside of the arc-shaped supporting plate 64. And through the clamping portion 642, the packaging can 4 can be clamped and fixed when needed. In addition, in the non-clamping state, the distance value between two adjacent limiting portions 641 is less than the maximum bottle diameter value of the packaging can 4, and the distance value between two adjacent clamping portions 642 is greater than the maximum bottle diameter value of the packaging can 4. And the distance value between the two clamping portions 642 can satisfy the position where the two arc-shaped supporting plates 64 rotate to correspond to the packaging can 4.

[0046] In this embodiment, a control mechanism 7 is arranged on the arc-shaped supporting plate 64. The control mechanism 7 includes a movable groove formed inside the arc-shaped supporting plate 64. A second spring damper 71 is fixedly connected inside the movable groove. A connecting frame 72 is fixedly connected to the outside of the second spring damper 71. A rubber wheel 73 is rotatably connected to the inner side surface of the connecting frame 72. The end of the rubber wheel 73 extends to the outside of the arc-shaped supporting plate 64. A torsion spring 74 is arranged between the rubber wheel 73 and the connecting frame 72.

[0047] The control mechanism 7 further includes a gear 75 rotatably connected to the surface of the connecting frame 72. A limiting groove 79 is formed inside the connecting frame 72. A guide plate 76 is slidably connected to the inner side surface of the limiting groove 79. A rack 77 is fixedly connected to the outside of the guide plate 76. A pressing button 78 is arranged inside the movable groove. Under the limiting and guiding action of the limiting groove 79, the guide plate 76 can only slide linearly along the inner side surface of the limiting groove 79.

[0048] The gear 75 meshes with the rack 77. The pressing button 78 is electrically connected to the first motor 621. After the pressing button 78 is pressed down, the PLC controller first controls the second motor to drive the bidirectional screw 652 to rotate reversely, and then controls the first motor 621 to drive the worm 622 to rotate reversely.

[0049] In this embodiment, a double-head granule filling device for preparing oseltamivir phosphate dry suspension includes the above-mentioned double-head granule filling device. This double-head granule filling device for preparing oseltamivir phosphate dry suspension is used to prepare oseltamivir phosphate dry suspension;

[0050] It further includes two calibration plates 8 fixedly installed on the workbench 1. The two calibration plates 8 are symmetrically arranged on both sides above the conveyor belt 2.

[0051] When there is no packaging can 4 under the telescopic filling pipe on the side close to the incoming direction of the packaging can 4, the double-head filling unit 3 does not perform the filling operation. At this time, the PLC controller will control the conveyor belt 2 to perform a feeding action for half of the distance, so that the packaging can 4 placed on its surface can continue to be conveyed forward. And, at this time, the first motor 621 will be started. After the first motor 621 is started, it drives the worm 622 to rotate. The rotation of the worm 622 drives the worm wheel 623 to rotate. The rotation of the worm wheel 623 drives the cross plate 61 fixedly connected to its coaxial to rotate, so that the cross plate 61 rotates to be perpendicular to the conveying direction of the conveyor belt 2. And the arc-shaped support plate 64 rotates synchronously with the cross plate 61 to a position corresponding to the packaging can 4. At this time, the infrared sensor 66 detects the presence of the packaging can 4, so that the second motor drives the bidirectional screw 652 to rotate, and the two guide blocks 653 on both sides thereof rotate towards each other synchronously. When the guide blocks 653 move, they drive the two arc-shaped support plates 64 to approach each other, so that they can gradually contact the packaging can 4 and clamp it. And when the arc-shaped support plate 64 contacts the surface of the packaging can 4 and no longer moves, at this time, the bidirectional screw 652 continues to rotate, so that the two guide blocks 653 continue to move and perform relative movement with the arc-shaped support plate 64, so that the first spring damper 655 can be compressed. After the first spring damper 655 is compressed, it will exert an extrusion force on the arc-shaped support plate 64, so that the contact pressure between the arc-shaped support plate 64 and the packaging can 4 can be adjusted to meet the need for clamping it;

[0052] After the arc-shaped support plate 64 clamps the packaging can 4, at this time, the electric cylinder 657 is activated, and its telescopic end contracts upward and drives the limiting baffle 63 to move upward. When the limiting baffle 63 moves upward, it drives the arc-shaped support plate 64 to move upward. When the arc-shaped support plate 64 moves upward, it drives the clamped packaging can 4 to move upward, separating its bottom from the conveyor belt 2. Thus, when the conveyor belt 2 conveys the rear packaging can 4 forward, the operation of the conveyor belt 2 will not affect this packaging can 4, enabling this packaging can 4 to remain in its original position.

[0053] When the arc-shaped support plate 64 clamps the packaging can 4, the rubber wheel 73 on its surface will contact and press against the surface of the packaging can 4, causing the rubber wheel 73 to move towards the inside of the arc-shaped support plate 64 and driving the connecting frame 72 to move to compress the second spring damper 71. When the connecting frame 72 moves, it drives the rack 77 to move. During the movement of the rack 77, it will gradually approach the pressing button 78. When the rubber wheel 73 is squeezed to the limit position, at this time, the rack 77 moves to directly below the pressing button 78;

[0054] After the rear packaging can 4 is conveyed to the designated position, the telescopic filling pipe in the upper double-headed filling unit 3 moves downward and sleevs on the top of the packaging can 4. Since this packaging can 4 is in a lifted state, when it is subjected to a downward pressure at this time, the packaging can 4 will move downward and drive the rubber wheel 73 to rotate. When the rubber wheel 73 rotates, it drives the gear 75 to rotate. When the gear 75 rotates, it drives the rack 77 to move upward. When the rack 77 moves upward, it gradually approaches the pressing button 78. When the packaging can 4 moves downward to contact the surface of the conveyor belt 2, at this time, the rack 77 moves upward to contact and press against the pressing button 78. After the pressing button 78 is pressed, it causes the motor two to drive the bidirectional screw 652 to rotate in the reverse direction, causing the two arc-shaped support plates 64 to move away from each other and release the clamping of the packaging can 4. Then, the motor one 621 and the electric cylinder 657 are activated. The motor one 621 drives the worm 622 to rotate in the reverse direction, causing the cross plate 61 to rotate in the reverse direction and drive the arc-shaped support plate 64 to rotate back to its original position. Moreover, the telescopic end of the electric cylinder 657 extends downward, causing the arc-shaped support plate 64 to be reset.

[0055] Only some exemplary embodiments of the present invention have been described by way of illustration above. Undoubtedly, for those of ordinary skill in the art, without departing from the spirit and scope of the present invention, the described embodiments can be modified in various different ways. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the protection scope of the claims of the present invention.

Claims

1. A double-headed granule filling device, comprising a workbench (1), a conveyor belt (2) arranged on the workbench (1), and a double-headed filling unit (3) arranged at the top of the workbench (1). A detection unit is arranged at the bottom of the double-headed filling unit (3), and it is characterized in that, A number of packaging cans (4) are arranged on the conveyor belt (2). A mounting box (5) is fixedly installed on the top of the workbench (1), and a calibration mechanism (6) is arranged on the mounting box (5). The calibration mechanism (6) includes a moving cavity opened inside the mounting box (5). A cross plate (61) is rotatably connected to the inner side surface of the moving cavity. A driving component (62) is arranged outside the cross plate (61). A limiting baffle (63) is arranged at the bottom of the cross plate (61). Two symmetrical arc-shaped supporting plates (64) are arranged outside the limiting baffle (63). An auxiliary component (65) is arranged outside the arc-shaped supporting plate (64). An infrared sensor (66) is embedded on the surface of the arc-shaped supporting plate (64). A control mechanism (7) is arranged on the arc-shaped supporting plate (64). The control mechanism (7) includes a moving slot opened inside the arc-shaped supporting plate (64). A second spring damper (71) is fixedly connected inside the moving slot. A connecting frame (72) is fixedly connected to the outside of the second spring damper (71). A rubber wheel (73) is rotatably connected to the inner side surface of the connecting frame (72). The end of the rubber wheel (73) extends to the outside of the arc-shaped supporting plate (64). A torsion spring (74) is arranged between the rubber wheel (73) and the connecting frame (72). The control mechanism (7) further includes a gear (75) rotatably connected to the surface of the connecting frame (72). A limiting slot (79) is opened inside the connecting frame (72). A guide plate (76) is slidably connected to the inner side surface of the limiting slot (79). A rack (77) is fixedly connected to the outside of the guide plate (76). A push button (78) is arranged inside the moving slot. The gear (75) is meshed with the rack (77). When the rear packaging can (4) is conveyed to the designated position, the telescopic filling pipe in the upper double-head filling unit (3) moves downward and sleeves on the top of the packaging can (4) in the lifted state. The packaging can (4) moves downward and drives the rubber wheel (73) to rotate. When the packaging can (4) moves downward to contact the surface of the conveyor belt (2), the rack (77) moves upward to contact and press the push button (78). The PLC controller first controls the second motor to drive the bidirectional screw rod (652) to rotate in the reverse direction, and the two arc-shaped supporting plates (64) move away from each other and release the clamping of the packaging can (4).

2. The double-head particle filling device according to claim 1, characterized in that, The driving component (62) includes a first motor (621) fixedly installed inside the moving cavity. A worm (622) is fixedly connected to the outside of the output shaft of the first motor (621). A worm gear (623) is meshed with the outside of the worm (622). The worm gear (623) is coaxially fixedly connected with the cross plate (61).

3. The dual-head granule filling device according to claim 1, characterized in that, The auxiliary component (65) includes a cavity (656) opened at the bottom of the cross plate (61). An electric cylinder (657) is fixedly connected inside the cavity (656). The bottom of the telescopic end of the electric cylinder (657) is fixedly connected to the limiting baffle (63).

4. A double-headed granule filling device according to claim 1, characterized in that, The auxiliary component (65) further includes a guiding groove (651) formed on the surface of the limiting baffle (63). A bidirectional screw rod (652) is rotatably connected to the inner side surface of the guiding groove (651). Two guiding blocks (653) are threadedly connected to the outer part of the bidirectional screw rod (652). A sliding groove (654) is formed on the inner side surface of the guiding block (653). The arc-shaped supporting plate (64) is slidably connected to the inner side surface of the sliding groove (654). A first spring damper (655) is fixedly connected between one side of the inner part of the sliding groove (654) far away from the other guiding block (653) and the arc-shaped supporting plate (64).

5. A double-headed granule filling device according to claim 4, characterized in that, The two guiding blocks (653) are symmetrically arranged on both sides of the bidirectional screw rod (652). A second motor is arranged inside the limiting baffle (63). The output shaft of the second motor is fixedly connected to the bidirectional screw rod (652).

6. The dual-head granule filling device according to claim 1, wherein, The arc-shaped supporting plate (64) includes a limiting part (641) and a clamping part (642).

7. A double-headed granule filling device according to claim 2, characterized in that, The pressing button (78) is electrically connected to the first motor (621).

8. A double-headed granule filling device for preparing oseltamivir phosphate dry suspension, characterized in that, It includes the double-head granule filling device as described in any one of claims 1-7. The double-head granule filling equipment for preparing oseltamivir phosphate dry suspension is used for preparing oseltamivir phosphate dry suspension; It further includes two calibration plates (8) fixedly installed on the workbench (1). The two calibration plates (8) are symmetrically arranged on both sides above the conveyor belt (2).

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