A double balloon reservoir device for treating brain gliomas

The design of the double-balloon fluid storage device solves the problems of uneven drug release and fluid precipitation after glioma surgery, achieving uniform drug release and independent absorption of the collected fluid, thus addressing the drug release effect and practical technical challenges or needs.

CN116549816BActive Publication Date: 2025-12-05HAINAN KANGDUN BIOPHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202310188152.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-03-01
Publication Date
2025-12-05
Estimated Expiration
2043-03-01

AI Technical Summary

Technical Problem

In existing technologies, the release effect of radiotherapy drugs after glioma surgery is poor, the fluid collection and drug release are uneven, and it may also cause the side wall of the intracranial tumor resection cavity to contract, affecting the drug release effect and fluid collection.

Method used

The device employs a dual-balloon reservoir, comprising a drug reservoir and a collection reservoir. The drug reservoir consists of an outer collection and absorption reservoir and an inner drug release reservoir. Uniform drug release and independent absorption of the collection reservoir are achieved through the release tube and aspiration port. A one-way valve is used to prevent the collection reservoir from entering the drug reservoir. The design of the reservoir and catheter allows for multiple punctures and independent operation.

Benefits of technology

It achieves uniform drug release and independent absorption of collected fluid, avoids intracranial tumor resection cavity damage, maintains drug release effect, has good adhesion, and excellent fluid collection and drainage effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a double-balloon liquid storage device for treating brain glioma, which comprises a medicine balloon, a liquid storage balloon and a groove body, the medicine balloon is communicated with the liquid storage balloon through a catheter, the medicine balloon comprises a liquid absorption outer balloon and a medicine release inner balloon, the medicine release inner balloon is arranged in the liquid absorption outer balloon, a plurality of release pipes penetrating through the liquid absorption outer balloon are communicated with the medicine release inner balloon, a first one-way valve is arranged in each release pipe, the release pipes are provided with a plurality of release holes communicated with the liquid absorption outer balloon, a plurality of liquid absorption holes are arranged on the liquid absorption outer balloon, the pipe openings of the release pipes and the liquid absorption holes are staggered with each other, the liquid storage balloon comprises a liquid collection balloon and a medicine storage balloon, the medicine storage balloon is communicated with the liquid collection balloon through a connecting piece, and the liquid storage balloon is connected in the groove body through the connecting piece.
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Description

TECHNICAL FIELD

[0001] The application relates to the technical field of medical devices, in particular to a double-balloon liquid storage device for treating brain glioma. BACKGROUND

[0002] Brain glioma is the most common primary intracranial tumor caused by canceration of brain and spinal cord glial cells, can be removed by surgery, and postoperative adjuvant radiotherapy is needed. When radiotherapy is performed, the radiotherapy drug needs to be released into the intracranial brain tumor resection cavity, and the excess drug or collected liquid after release needs to be precipitated. The existing postoperative radiotherapy drug release effect is poor. For example, a kind of auxiliary device for postoperative radiotherapy of brain glioma disclosed in patent No. CN205145384U comprises a drug storage tank, a medical catheter and a balloon containing a radiotherapy drug. The drug storage tank comprises a tank body, a plug and a tank cover. The inside of the tank body has an integrated cavity with a cylindrical upper part and a conical lower part. The bottom of the cavity is provided with a catheter, and the outer surface of the upper part of the tank body is provided with external threads. The plug is a cylinder with a hemispherical body connected to the top. The top of the tank cover is provided with a hole, and the inner surface of the sidewall of the tank cover is provided with internal threads. The cylindrical part of the plug is movably connected to the cavity of the tank body, and the tank cover is threadedly connected to the tank body, so that the hemispherical part of the plug protrudes out of the hole in the top of the tank cover. This technical solution has certain defects for postoperative radiotherapy of brain glioma. The release of the drug and the collection of the liquid in the intracranial brain glioma resection cavity exist certain problems. The collected liquid and the drug release are uniformly realized through the balloon. When the collected liquid in the balloon is completely extracted through the syringe, the balloon will shrink, and cannot support the side wall of the intracranial brain tumor resection cavity, causing the side wall of the intracranial brain tumor resection cavity to shrink. If the collected liquid is not completely removed, the drug will mix with the collected liquid when the drug is injected into the balloon again, affecting the release of the drug and reducing the drug release effect. SUMMARY

[0003] The application provides a double-balloon liquid storage device for treating brain glioma. The drug can be released into the intracranial tumor resection cavity through multiple punctures, and the collected liquid can be absorbed. The release of the drug and the collection of the liquid can be independently performed, the adhesion is good, and intracranial tumor resection cavity injury can be effectively avoided.

[0004] In order to achieve the above object, the application provides a double-balloon liquid storage device for treating brain glioma, which comprises a medicine balloon, a liquid storage balloon and a groove body, the medicine balloon is communicated with the liquid storage balloon through a catheter, the medicine balloon comprises a liquid absorption outer balloon and a medicine release inner balloon, the medicine release inner balloon is arranged inside the liquid absorption outer balloon, a plurality of release pipes penetrating through the liquid absorption outer balloon are communicated with the medicine release inner balloon, a first one-way valve is arranged in each release pipe, the release pipes are provided with a plurality of release holes communicated with the liquid absorption outer balloon, a plurality of liquid absorption holes are arranged on the liquid absorption outer balloon, the pipe openings of the release pipes and the liquid absorption holes are staggered with each other, the liquid storage balloon comprises a liquid storage balloon and a medicine storage balloon, the medicine storage balloon is communicated with the liquid storage balloon through a connecting piece, and the liquid storage balloon is connected in the groove body through the connecting piece.

[0005] Preferably, the catheter comprises a medicine delivery pipe and a liquid discharge pipe, two ends of the medicine delivery pipe are communicated with the medicine release inner balloon and the medicine storage balloon respectively, two ends of the liquid discharge pipe are communicated with the liquid absorption outer balloon and the liquid storage balloon respectively, and the medicine delivery pipe is arranged inside the liquid discharge pipe.

[0006] Preferably, the liquid discharge pipe comprises a pipe body and a plurality of elastic rods, and the plurality of elastic rods are uniformly distributed in the pipe wall of the pipe body in the circumferential direction.

[0007] Preferably, the bottom of the groove body is provided with a sealing hole, and a sealing body is slidingly connected with the catheter, and the sealing body is sealed at the sealing hole.

[0008] Preferably, a plurality of second one-way valves are arranged in the liquid discharge pipe.

[0009] Preferably, the connecting piece comprises a sealing plug, a connecting sleeve and a connecting body, the sealing plug is connected with the connecting sleeve, the connecting sleeve is connected with the groove body, the connecting body is connected with the bottom of the sealing plug, the free end of the connecting body penetrates through the liquid storage balloon and is connected with the medicine storage balloon, a liquid storage groove is arranged on the connecting body and located in the liquid storage balloon.

[0010] Preferably, a plurality of through holes communicated with the liquid storage groove are arranged on the connecting body.

[0011] Preferably, an outer thread is arranged on the upper part of the groove body, an inner thread is arranged on the connecting sleeve, and the connecting sleeve is threadedly connected with the groove body.

[0012] Compared with the prior art, the application has the following beneficial effects:

[0013] The application provides a double-balloon liquid storage device for treating brain glioma, which is characterized in that a medicine balloon is arranged in a cranial brain tumor resection cavity, a groove body is fixed between a scalp and a skull to fix the device, a medicine storage balloon is fixed in the groove body through a connecting piece and can be punctured multiple times to release medicine into the cranial brain tumor resection cavity and to absorb the liquid, the medicine is uniformly released through cooperation of a release pipe and a liquid absorption hole, and when the medicine enters an outer liquid absorption balloon, the medicine can be cooperated with a plurality of release pipes to support the side wall of the cranial brain tumor resection cavity, and the release of the medicine and the liquid absorption can be independently carried out through cooperation of the outer liquid absorption balloon, an inner medicine release balloon, a liquid absorption balloon, the medicine storage balloon and a catheter, and the liquid absorption into the inner medicine release balloon can be effectively avoided through cooperation of a first one-way valve, the cranial brain tumor resection cavity can be effectively avoided from being damaged, the medicine release effect is uniform, the adhesion is good, and the liquid discharge effect is good. BRIEF DESCRIPTION OF DRAWINGS

[0014] In order to more clearly illustrate the technical solutions in the embodiments of the application, the following will briefly introduce the drawings needed to be used in the embodiment description. Obviously, the drawings in the following description are only preferred embodiments of the application, and other drawings can be obtained by those skilled in the art without any creative labor.

[0015] Figure 1 FIG. 1 is a cross-sectional structure schematic diagram of the double-balloon liquid storage device for treating brain glioma;

[0016] Figure 2 FIG. 2 is an enlarged structure schematic diagram of a part A in FIG. 1; Figure 1

[0017] Figure 3 FIG. 3 is a cross-sectional structure schematic diagram of a catheter;

[0018] Figure 4 FIG. 4 is a partial cross-sectional structure schematic diagram of the double-balloon liquid storage device for treating brain glioma;

[0019] Figure 5 FIG. 5 is an enlarged structure schematic diagram of a part B in FIG. 4; Figure 4

[0020] Reference signs: 1, medicine balloon; 2, outer liquid absorption balloon; 3, inner medicine release balloon; 4, release pipe; 5, first one-way valve; 6, release hole; 7, liquid storage balloon; 8, liquid absorption balloon; 9, medicine storage balloon; 10, groove body; 11, catheter; 12, medicine delivery pipe; 13, liquid discharge pipe; 14, connecting piece; 15, sealing plug; 16, connecting sleeve; 17, connecting body; 18, liquid absorption groove; 19, through hole; 20, pipe body; 21, elastic rod; 22, sealing hole; 23, sealing body; 24, second one-way valve. DETAILED DESCRIPTION ​​

[0021] To better understand the structure, functional features, and advantages of the present invention, preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings:

[0022] Example 1:

[0023] like Figures 1 to 5 As shown, this invention provides a double-balloon reservoir device for treating gliomas, comprising a drug capsule 1, a reservoir 7, and a tank 10. The drug capsule 1 is connected to the reservoir 7 via a conduit 11. The drug capsule 1 includes a collection and absorption outer capsule 2 and a drug release inner capsule 3. The drug release inner capsule 3 is located inside the collection and absorption outer capsule 2. The drug release inner capsule 3 is connected to several release tubes 4 passing through the collection and absorption outer capsule 2 to release the drug. Each release tube 4 is equipped with a first one-way valve 5 to prevent the drug from entering the drug release inner capsule 3 during collection and absorption. Each release tube 4 has several release holes 6 communicating with the collection and absorption outer capsule 2. The collection and absorption outer capsule 2 has several suction holes (not shown) to uniformly absorb the collected liquid. The openings of the release tubes 4... The suction hole (not shown) is offset from the release tube 4. When the drug is released, it can be released simultaneously through the release tube 4 and the suction hole (not shown). The opening of the release tube 4 is offset from the suction hole (not shown) to release the drug evenly. The reservoir 7 includes a collection bladder 8 and a drug storage bladder 9. The drug storage bladder 9 is connected to the collection bladder 8 through a connector 14. The drug storage bladder 9 is connected to the tank 10 through the connector 14. The tank 10 is cylindrical and facilitates the stabilization of the reservoir bladder 7. The bottom of the tank 10 is provided with a sealing hole 21. The conduit 11 is slidably connected to a sealing body 23. The sealing body 23 seals the sealing hole 21, sealing the tank 10 and preventing the collected liquid from entering the tank 10. This invention allows for independent drug release and absorption collection.

[0024] Specifically, the catheter 11 includes a drug delivery tube 12 and a drainage tube 13. The two ends of the drug delivery tube 12 are respectively connected to the drug release inner capsule 3 and the drug storage capsule 9, so that the drug in the drug storage capsule 9 can be delivered into the drug release inner capsule 3 to facilitate drug release. The two ends of the drainage tube 13 are respectively connected to the liquid absorption outer capsule 2 and the liquid collection capsule 8 to realize the drainage of the collected liquid. The drug delivery tube 12 is located inside the drainage tube 13. The drainage tube 13 is provided with several second one-way valves 24 to prevent the collected liquid from flowing back into the liquid collection capsule 8.

[0025] Specifically, the drain pipe 13 includes a pipe body 20 and a plurality of elastic rods 21. The plurality of elastic rods 21 are evenly distributed in the circumferential direction within the pipe wall of the pipe body 20, which can support the conduit 11 and prevent the conduit 11 from being bent, thus maintaining the drug delivery and liquid collection delivery effect.

[0026] Embodiment 2

[0027] Referring to Figures 1 to 5 The difference between the embodiment and Embodiment 1 is that the connecting member 14 comprises a sealing plug 15, a connecting sleeve 16 and a connecting body 17, the sealing plug 15 is connected with the connecting sleeve 16, the connecting sleeve 16 is connected with the groove body 10, the sealing plug 15 is fixed so that the sealing plug 15 seals the groove body 10, the connecting body 17 is connected with the bottom of the sealing plug 15, the free end of the connecting body 17 penetrates through the liquid collecting pocket 8 and is connected with the medicine storage pocket 9, the connecting body 17 is provided with a liquid collecting groove 18, the liquid collecting groove 18 is located in the liquid collecting pocket 8, the medicine release inner pocket 3 or the liquid collecting absorption outer pocket 2 can be punctured repeatedly, the medicine injection or the liquid collecting extraction is realized, the connecting body 17 is provided with a plurality of through holes 19 which are in communication with the liquid collecting groove 18, the liquid collecting groove 18 is convenient for the liquid collecting, wherein the upper part of the groove body 10 is provided with external threads, the connecting sleeve is provided with internal threads, the connecting sleeve 16 is threadedly connected with the groove body 10.

[0028] In use, the medicine pocket 1 of the device is placed in the resection cavity, the groove body 10 is fixed between the scalp and the skull, the skull is closed and the scalp is sutured, in radiotherapy, the inner part of the medicine storage pocket 9 is inserted through the connecting body 17 by the syringe, the medicine flows into the medicine release inner pocket 3 through the medicine delivery pipe 12, the medicine is directly released into the resection cavity through the release pipe 4, at the same time, the medicine is gathered into the liquid collecting absorption outer pocket 2 through the release port of the release pipe 4 and is released into the resection cavity through the liquid absorbing hole (not marked) of the liquid collecting absorption outer pocket 2, the medicine is released in the same way, the medicine can be uniformly released, and the liquid collecting absorption outer pocket 2 can be kept in the open state and can play a supporting role; when there is liquid collecting in the resection cavity, the liquid collecting is absorbed into the liquid collecting absorption outer pocket 2 through the liquid absorbing hole (not marked) due to the effect of the intracranial pressure, the first one-way valve 5 can avoid the liquid collecting from entering the medicine release inner pocket 3, the liquid collecting flows into the liquid collecting pocket 8 through the liquid discharging pipe 13, the liquid collecting is extracted by the syringe which is placed in the liquid collecting groove 18 through the connecting body 17.

[0029] The above is only the preferred embodiment of the present application, and does not limit the present application in any form. Any skilled person in the art can make many possible changes and modifications to the technical solution of the present application or modify it into equivalent embodiments with equivalent changes without departing from the scope of the technical solution of the present application. Therefore, any modification, equivalent change and modification made to the above embodiments according to the technical solution of the present application, which does not depart from the content of the technical solution of the present application, belongs to the protection scope of the technical solution of the present application.

Claims

1. A double balloon reservoir device for treating brain glioma, characterized by: The application relates to a medicine capsule, a liquid storage capsule and a groove body, the medicine capsule is communicated with the liquid storage capsule through a conduit, the medicine capsule comprises a liquid absorption outer capsule and a medicine release inner capsule, the medicine release inner capsule is arranged in the liquid absorption outer capsule, a plurality of release pipes penetrating through the liquid absorption outer capsule are communicated with the medicine release inner capsule, a first one-way valve is arranged in each release pipe, the release pipes are provided with a plurality of release holes communicated with the liquid absorption outer capsule, a plurality of liquid absorption holes are arranged on the liquid absorption outer capsule, the pipe openings of the release pipes and the liquid absorption holes are staggered with each other, the liquid storage capsule comprises a liquid storage capsule and a medicine storage capsule, the medicine storage capsule is communicated with the liquid storage capsule through a connecting piece, the liquid storage capsule is connected in the groove body through the connecting piece, the conduit comprises a medicine conveying pipe and a liquid discharging pipe, two ends of the medicine conveying pipe are respectively communicated with the medicine release inner capsule and the medicine storage capsule, two ends of the liquid discharging pipe are respectively communicated with the liquid absorption outer capsule and the liquid storage capsule, and the medicine conveying pipe is arranged in the liquid discharging pipe.

2. A double balloon reservoir device for treating brain gliomas as claimed in claim 1, wherein: The liquid discharging pipe comprises a pipe body and a plurality of elastic rods, and the elastic rods are uniformly distributed in the pipe wall of the pipe body in the circumferential direction.

3. A double balloon reservoir device for treating brain gliomas as claimed in claim 1, wherein: The bottom of the groove body is provided with a sealing hole, a sealing body is slidably connected with the conduit, and the sealing body is sealed at the sealing hole.

4. The dual-balloon reservoir device for treating brain gliomas of claim 1, wherein: A plurality of second one-way valves are arranged in the liquid discharging pipe.

5. The dual-balloon reservoir device for treating brain gliomas of claim 1, wherein: The connecting piece comprises a sealing plug, a connecting sleeve and a connecting body, the sealing plug is connected with the connecting sleeve, the connecting sleeve is connected with the groove body, the connecting body is connected with the bottom of the sealing plug, the free end of the connecting body is connected with the medicine storage capsule through the liquid storage capsule, a liquid storage groove is arranged on the connecting body and located in the liquid storage capsule.

6. A double balloon reservoir device for treating brain gliomas as claimed in claim 5, wherein: A plurality of through holes communicated with the liquid storage groove are arranged on the connecting body.

7. A double balloon reservoir device for treating brain gliomas as claimed in claim 5 wherein: The upper portion of the groove body is provided with external threads, the connecting sleeve is provided with internal threads, and the connecting sleeve is threadedly connected with the groove body.

Citation Information

Patent Citations

  • Glioma postoperative radiation therapy's auxiliary device

    CN205145384U

  • Drug delivery device

    CN111330137A

  • Balloon catheter

    CN113546281A