A particle-laden scaffold delivery system

Abstract

A particle-laden stent delivery system is disclosed. The system includes an inner tube and an outer tube. The outer tube includes a proximal end opening, a distal end opening, and a first lumen extending from the proximal end opening to the distal end opening. The inner tube is slidably disposed within the first lumen. A stent-receiving cavity is formed between a distal end section of the inner tube and a sidewall of the first lumen for receiving a collapsed particle-laden stent. The system further includes an anchor and a stent-retrieving tube. The anchor is fixedly connected to the inner tube and is disposed within the stent-receiving cavity for engaging the particle-laden stent during stent retrieval and disengaging the particle-laden stent during stent release. The stent-retrieving tube is detachably connected to a distal end of the outer tube and is in communication with the first lumen of the outer tube. When the outer tube is moved distally toward the inner tube, the stent-retrieving tube is moved distally toward an end of the particle-laden stent in an expanded state and causes the particle-laden stent to collapse inwardly through a corresponding section of the stent-retrieving tube and into the first lumen of the outer tube.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically to a particle-carrying stent delivery system for use in cavities. Background Technology

[0002] Currently, stents have a wide range of applications, including the treatment of strictures in the bile ducts, portal vein, trachea, main bronchus, esophagus, intestines, and various organic stenosis. Existing techniques typically involve manually squeezing the stent into the delivery tube of a stent delivery system, and then using a guidewire and bronchoscope to implant the stent at the lesion site, completing stent release.

[0003] For solid tumors within cavities, combining I-125 radioactive particles with a particle-carrying scaffold represents a novel treatment approach. This implantation procedure involves calculating the required dose using a TPS system, loading the particles into the released particle-carrying scaffold according to the desired dose, and then retrieving the particle-carrying scaffold back into a delivery system for use during the procedure. All of these steps are completed within a hospital operating room.

[0004] Traditional particle-carrying stent delivery systems lack a retrieval function. Furthermore, after being loaded with particles, the released particle-carrying stent is too thick to be easily inserted into the implanter. Additionally, I-125 radioactive particles are radioactive, and surgeons face the risk of radiation exposure when manually squeezing the stent back into the delivery system. Summary of the Invention

[0005] Purpose of the invention: The technical problem to be solved by the present invention is to provide a particle-carrying scaffold delivery system that addresses the shortcomings of the prior art, and facilitates the recovery and release of the scaffold.

[0006] To address the aforementioned technical problems, this invention discloses a particle-carrying scaffold delivery system. The delivery system includes an inner tube and an outer tube. The outer tube includes a proximal end opening, a distal end opening, and a first inner cavity extending from its proximal end opening to its distal end opening. The inner tube is slidably fitted within the first inner cavity of the outer tube. A scaffold receiving cavity is formed between the distal section of the inner tube and the sidewall of the first inner cavity of the outer tube for accommodating a particle-carrying scaffold in a retracted state. The system also includes an anchoring member and a scaffold retrieval tube. The anchoring member is fixedly connected to the inner tube and located within the scaffold receiving cavity. The anchoring member is used to connect to the proximal end of the particle-carrying scaffold during retrieval and to disengage from the proximal end of the particle-carrying scaffold during release. The scaffold retrieval tube is detachably connected to the distal end of the outer tube and communicates internally with the first inner cavity of the outer tube. As the outer tube moves toward the far end of the inner tube, the stent recovery tube moves toward the end of the particle-carrying stent that is in an expanded state, causing the corresponding section of the particle-carrying stent that passes through the stent recovery tube to retract inward and enter the first inner cavity of the outer tube.

[0007] Specifically, the anchoring component includes a collar and a plurality of anchor posts. The collar is fixedly sleeved on the inner tube, and the anchor posts are spaced circumferentially around the collar at the proximal outer periphery of the collar. A groove is formed inwardly on the outer peripheral sidewall of the collar between two adjacent anchor posts. This groove extends axially along the collar and is used to accommodate the braided filaments at the proximal end of the particle-carrying support when it is in a retracted state.

[0008] Specifically, the support recovery tube is an elastic sleeve structure, including a trumpet-shaped compression section, an annular recovery section connected to the small end of the trumpet-shaped compression section and communicating with the interior of the trumpet-shaped compression section, and a slit penetrating the side wall of the support recovery tube. The distal end of the annular recovery section, which penetrates the outer tube, is sleeved with the outer tube, and the connection between the annular recovery section and the outer tube is smoothly transitioned.

[0009] Specifically, the system includes a guide head fixed to the distal end of the inner tube and a developing ring fixedly sleeved on the outside of the inner tube. The guide head, the inner tube, the developing ring, and the first inner wall of the outer tube enclose the support receiving cavity.

[0010] Furthermore, it also includes a middle tube and a middle tube fixing handle, wherein the middle tube is sleeved between the outer tube and the inner tube. The distal end of the middle tube is fixedly connected to the imaging ring, and the proximal end is fixedly connected to the middle tube fixing handle.

[0011] Furthermore, it also includes a booster tube and an inner tube fixing handle, the booster tube being sleeved between the middle tube and the inner tube. The distal end of the booster tube extends into the outer tube.

[0012] Specifically, it also includes a locking device located between the distal end of the outer tube and the distal end of the inner tube, used to restrict the relative sliding of the inner tube and the outer tube in the axial direction.

[0013] Specifically, the locking device includes a first locking connector and a second locking connector. The first locking connector is fixedly connected to the proximal end of the outer tube, and the distal end of the inner tube extends into the first inner cavity of the outer tube after passing through the second locking connector and the first locking connector in sequence. The second locking connector is rotatably sleeved on the outside of the inner tube. The first locking connector includes a locking portion and a first threaded connection portion in sequence along the radial direction. The second locking connector includes a pressing portion that cooperates with the locking portion and a second threaded connection portion that cooperates with the first threaded connection portion. The second locking connector and the first locking connector are screwed together through the first threaded connection portion and the second threaded connection portion. The pressing portion is used to press the locking portion inward and tighten it around the inner tube during the screwing connection process.

[0014] Specifically, the first locking connector includes a movable handle and a locking clamp. The locking clamp is fixedly connected to the movable handle to achieve a fixed connection between the first locking connector and the outer tube. The locking part is the proximal section of the locking clamp, and the first threaded connection part is an internal thread section located near the proximal end of the movable handle. The second locking connector is a locking sleeve. The second threaded connection part is an external thread section located at the distal end of the locking sleeve. The pressing part is an inclined surface located on the inner circumferential sidewall of the distal end of the locking sleeve and inclined inward toward the proximal end. During the screwing process, the inclined surface presses against the proximal end of the locking clamp and pulls inward to tighten the inner tube.

[0015] Specifically, the guide head has a guide hole. The inner tube includes a proximal end opening, a distal end opening, and a second inner cavity extending from the proximal end opening to the distal end opening. The guide hole of the guide head communicates with the second inner cavity to form a guide wire channel.

[0016] Beneficial effects:

[0017] (1) This application provides a particle-carrying stent delivery system, which includes an anchor and a stent retrieval tube. The anchor is fixed to the inner tube and located within the stent receiving cavity. The particle-carrying stent is detachably connected to the anchor and its interior communicates with the distal end opening of the outer tube. During stent retrieval, as the outer tube moves toward the distal end of the inner tube, it drives the stent retrieval tube toward the expanded end of the particle-carrying stent. The stent retrieval tube guides the corresponding section of the particle-carrying stent passing through the stent retrieval tube to retract inward and enter the first inner cavity of the outer tube. After the outer tube moves a certain distance relative to the inner tube, the particle-carrying stent can be completely retracted and retrieved into the stent receiving cavity. During stent release into the body, after the outer tube moves a certain distance toward the proximal end of the inner tube, the particle-carrying stent can be completely and naturally released and detached from the anchor. Thus, the particle-carrying stent delivery system provided in this application achieves the functions of stent release and retrieval.

[0018] (2) Compared to the prior art where the particle-loaded stent is manually squeezed and pushed into the stent cavity segment by segment, this application uses an anchor to hold the proximal end of the particle-loaded stent and keep this segment in a folded state. When the outer tube moves toward the distal end of the inner tube, the stent retrieval tube moves toward the expanded end of the particle-loaded stent. The corresponding segment of the particle-loaded stent passing through the stent retrieval tube is continuously and smoothly folded inward under the guidance of the stent retrieval tube. This process of retrieval of the particle-loaded stent is more convenient and faster, which can improve the efficiency of the operation and save operation time. At the same time, since the operator does not need to manually squeeze and fold the particle-loaded stent segment by segment during the retrieval process, this application helps to reduce the radiation risk of radioactive particles to the operator.

[0019] (3) In one embodiment of this application, the stent recovery tube includes a trumpet-shaped compression section, an annular recovery section connected to and communicating with the interior of the trumpet-shaped compression section, and a slit penetrating the side wall of the stent recovery tube. Because the inner diameter of the trumpet-shaped compression section gradually decreases, it guides the corresponding section of the particle-carrying stent that passes through the stent recovery tube to converge inwards, allowing the corresponding section of the particle-carrying stent to converge continuously and smoothly inwards under the guidance of the trumpet-shaped compression section. By providing the annular recovery section at the small opening of the trumpet-shaped compression section and the slit penetrating the side wall of the stent recovery tube, the stent recovery tube forms an elastic sleeve structure. The annular recovery section is inserted into the outer tube from the distal end opening, and the annular recovery section forms a tight contact connection with the outer tube. This detachable connection method is simple in structure and easy to operate.

[0020] (4) This application applies to both stents carrying radioactive particles and ordinary self-expanding stents without particles. Attached Figure Description

[0021] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments, and the advantages of the present invention in the above and / or other aspects will become clearer.

[0022] Figure 1 This is a schematic diagram of the external structure of a particle-carrying support delivery system according to an embodiment of the present invention;

[0023] Figure 2 It is along Figure 1 A sectional view of line AA in the diagram;

[0024] Figure 3 yes Figure 2 A magnified view of a portion of region B shown;

[0025] Figure 4 This is a schematic diagram of a particle-carrying scaffold in an expanded state according to an embodiment of the present invention;

[0026] Figure 5 This is a schematic diagram of a particle-carrying support anchored in a particle-carrying support delivery system according to an embodiment of the present invention;

[0027] Figure 6 It is along Figure 5 A sectional view of the DD line in the middle;

[0028] Figure 7 yes Figure 5 A magnified view of a portion of region E shown;

[0029] Figure 8 This is a schematic diagram of the structure of a particle-carrying scaffold completely retracted within a particle-carrying scaffold delivery system according to an embodiment of the present invention;

[0030] Figure 9 yes Figure 8 A magnified view of a portion of region F shown;

[0031] Figure 10 This is a schematic diagram of the structure of an anchoring member provided in one embodiment of the present invention;

[0032] Figure 11 An embodiment of the present invention provides a particle-carrying scaffold anchored to... Figure 10 The diagram shows the structure of the anchoring component.

[0033] Figure 12 This is a schematic diagram of the structure of a support recycling tube provided in one embodiment of the present invention;

[0034] Figure 13 yes Figure 1 A magnified view of a portion of region C shown;

[0035] Figure 14 This is one embodiment of the present invention. Figure 5 The diagram shows a particle-carrying scaffold for loading radioactive particles.

[0036] The reference numerals in the attached drawings are as follows: delivery system 100, inner tube 101, outer tube 102, proximal end opening 103, distal end opening 104, first inner cavity 105, stent receiving cavity 106, anchoring element 107, stent retrieval tube 108, collar 109, anchoring post 110, groove 111, guide head 112, imaging ring 113, middle tube 114, middle tube fixing handle 115, push tube 116, inner tube fixing handle 117, locking device 118, first locking connector 119, second locking connector 120, locking part 121, first threaded connection part 122, compression part 123, second threaded connection part 124, movable handle 125, locking clamp 126, guide hole 127, second inner cavity 128, trumpet-shaped compression section 129, annular retrieval section 130, slit 131, particle-carrying stent 200, particle implanter 300. Detailed Implementation

[0037] The technical solution of this application will now be described in detail with reference to the accompanying drawings.

[0038] like Figure 1 and Figure 2 As shown, this application provides a particle-carrying scaffold delivery system for the retrieval and implantation of a particle-carrying scaffold 200. The particle-carrying scaffold 200 has a self-expanding characteristic; it can be externally squeezed into a contracted state and self-expanded and released after the external force is released. The delivery system 100 includes an inner tube 101 and an outer tube 102. The outer tube 102 includes a proximal end opening 103, a distal end opening 104, and a first inner cavity 105 extending from its proximal end opening 103 to its distal end opening 104. (As shown...) Figure 2 and Figure 3 As shown, the inner tube 101 is slidably fitted within the first inner cavity 105 of the outer tube 102. A support receiving cavity 106 is formed between the distal end of the inner tube 101 and the sidewall of the first inner cavity 105 of the outer tube 102 to accommodate the particle-carrying support 200 in a retracted state. Specifically, as... Figure 3 As shown, the system includes a guide head 112 fixed to the distal end of the inner tube 101 and a developing ring 113 fixedly sleeved on the outside of the inner tube 101. The guide head 112, the inner tube 101, the developing ring 113 and the side wall of the first inner cavity 105 of the outer tube 102 enclose the support receiving cavity 106.

[0039] like Figure 4As shown, in the prior art, the particle-carrying scaffold 200 is filled while it is in an expanded state. Before and during the implantation surgery, the operator needs to manually squeeze the scaffold loaded with radioactive particles segment by segment into the scaffold receiving cavity 106. This method poses a radiation risk and is also inefficient, thus prolonging the surgical time.

[0040] To facilitate the retrieval of the particle-carrying stent 200 into the stent receiving cavity 106, such as Figure 5 and Figure 6 As shown, the system also includes an anchor 107 and a support retrieval tube 108. The anchor 107 is fixedly connected to the inner tube 101 and located within the support receiving cavity 106. The anchor 107 is used to connect to the proximal end of the particle-carrying support 200 during the retrieval process and to disengage from the proximal end of the particle-carrying support 200 during the release process. Figure 7 As shown, the inner diameter of the support recovery tube 108 gradually decreases. In use, the support recovery tube 108 is sleeved on the outside of the inner tube 101. The small diameter end of the support recovery tube 108 is detachably connected to the far end of the outer tube 102, and the interior of the support recovery tube 108 communicates with the first inner cavity 105 of the outer tube 102.

[0041] The working process of recovering and releasing the support using the particle-carrying support delivery system provided in this application is as follows:

[0042] Before retrieval of the stent, the stent retrieval tube is installed at the distal end of the outer tube, and the distal end of the outer tube 102 is positioned proximal to the distal end of the inner tube 101, thus opening the stent receiving cavity 106. The expanded particle-carrying stent 200 to be retrieved is fitted onto the outside of the stent receiving cavity 106, and its proximal end is folded inward and anchored to the anchoring member 107, thereby connecting the proximal end of the particle-carrying stent 200 to the inner tube 101.

[0043] During stent retrieval, as the outer tube 102 moves distally relative to the inner tube 101, the stent retrieval tube 108 moves toward the expanded end of the particle-carrying stent 200, causing the corresponding portion of the particle-carrying stent 200 passing through the stent retrieval tube 108 to retract inwards and enter the first inner cavity 105 of the outer tube 102. After the outer tube 102 has moved distally a certain distance relative to the inner tube 101, the particle-carrying stent 200 can be completely retracted and retrieved into the stent receiving cavity 106, as shown below. Figure 8 and Figure 9 As shown. The stent retriever can be removed from the delivery system after stent retrieval and before stent implantation.

[0044] When the stent is released, as the outer tube 102 moves toward the proximal end of the inner tube 101 until the stent receiving cavity 106 is open, the particle-carrying stent 200 naturally expands and disengages from the anchor 107.

[0045] Specifically, such as Figure 10 As shown, the anchoring element 107 includes a collar 109 and a plurality of anchor posts 110. The collar 109 is fixedly sleeved on the inner tube 101. The anchor posts 110 are spaced apart circumferentially around the collar 109 near its proximal outer periphery. A groove 111 is formed inwardly recessed on the outer peripheral sidewall of the collar 109 between adjacent anchor posts 110, and the groove 111 extends axially along the collar 109. Figure 11 As shown, when the support is recovered, the proximal braided wire of the particle-carrying support 200 is hung on the anchor post 110 and the proximal braided wire of the particle-carrying support 200 in the retracted state is located in the corresponding groove 111.

[0046] Specifically, such as Figure 12 As shown, the support recovery tube 108 is an elastic sleeve structure, which can be made of plastic materials such as PP and PET, or stainless steel. The support recovery tube 108 includes a trumpet-shaped compression section 129, an annular recovery section 130 connected to and communicating with the interior of the trumpet-shaped compression section 129, and a slit 131 penetrating the side wall of the support recovery tube 108. The annular recovery section 130 is inserted into the distal end opening of the outer tube 102 and sleeved with the outer tube 102, and the connection between the annular recovery section 130 and the outer tube 102 is smooth.

[0047] like Figure 2 As shown, the guide head 112 is connected to the inner tube 101 and forms a guide wire channel. The guide wire passes through the guide wire channel to guide the delivery device to the lesion site.

[0048] Specifically, the guide head 11 is made of a polymer material with elastomer function and is generally tapered. The guide head 112 has a guide hole 127. The inner tube 101 includes a proximal end opening 103, a distal end opening 104, and a second inner cavity 128 extending from its proximal end opening 103 to its distal end opening 104. The guide hole 127 and the second inner cavity 128 communicate to form a guide wire channel.

[0049] like Figure 2As shown, the system also includes a central tube 114 and a central tube fixing handle 115. The central tube 114 is sleeved between the outer tube 102 and the inner tube 101, serving to support the outer tube 102 and improve the bending performance of the conveyor. The distal end of the central tube 114 is fixedly connected to the developing ring 113, and the proximal end is fixedly connected to the central tube fixing handle 115.

[0050] like Figure 2 As shown, the system also includes a booster tube 116 and an inner tube fixing handle 117. The booster tube 116 is sleeved between the middle tube 114 and the inner tube 101, serving to increase the strength of the pushing end. The distal end of the booster tube 116 extends into the outer tube 102.

[0051] like Figure 13 As shown, in order to facilitate the loading of radioactive particles into the particle-carrying scaffold and the implantation of the delivery system into the body, the system further includes a locking device 118 located between the distal end of the outer tube 102 and the distal end of the inner tube 101, for limiting axial relative sliding between the inner tube 101 and the outer tube 102, thereby ensuring that the particle-carrying scaffold is stably housed within the scaffold receiving cavity 106 during the introduction of the delivery system into the body. In one embodiment, as... Figure 12 As shown, the locking device 118 includes a first locking connector 119 and a second locking connector 120. The first locking connector 119 is fixedly connected to the proximal end of the outer tube 102. The distal end of the inner tube 101 passes through the second locking connector 120 and the first locking connector 119 in sequence and extends into the first inner cavity 105 of the outer tube 102. The second locking connector 120 is rotatably sleeved on the outside of the inner tube 101. The first locking connector 119 includes locking components in sequence along the radial direction. The second locking connector 120 includes a pressing part 123 that mates with the locking part 121 and a second threaded connection part 124 that mates with the first threaded connection part 122. The second locking connector 120 and the first locking connector 119 are screwed together via the first threaded connection part 122 and the second threaded connection part 124. The pressing part 123 is used to press the locking part 121 inward to tighten and hold the inner tube 101 during the tightening process. In a particular embodiment, such as Figure 13As shown, the first locking connector 119 includes a movable handle 125 and a locking clamp 126. The locking clamp 126 is fixedly connected to the movable handle 125 to achieve the fixed connection between the first locking connector 119 and the outer tube 102. The locking part 121 is the proximal section of the locking clamp 126, and the first threaded connection part 122 is an internal threaded section located at the proximal end of the movable handle 125. The second locking connector 120 is a locking sleeve, and the second threaded connection part 124 is an external threaded section located at the distal end of the locking sleeve. The pressing part 123 is an inclined surface located on the inner peripheral sidewall of the distal end of the locking sleeve and inclined inward toward the proximal end. When the distal end of the locking sleeve is inserted into the cavity and rotates toward the distal end, the inclined surface presses against the proximal end of the locking clamp 126 and pulls inward to hug the inner tube 101.

[0052] The process of recovering and releasing a particle-carrying scaffold using a particle-carrying scaffold delivery system according to this application is as follows:

[0053] Step 1, such as Figure 7 As shown, the stent retrieval tube 108 is installed at the distal end of the outer tube 102, and the distal end of the outer tube 102 is located near the distal end of the inner tube 101 so that the stent receiving cavity 106 is in an open state.

[0054] Step 2, Anchoring Support: (e.g.) Figure 6 As shown, the unloaded particle-carrying support 200 in an expanded state is fitted onto the outside of the support receiving cavity 106, and the proximal braided wire of the particle-carrying support 200 is hung on the anchor 107. At this time, the proximal section of the particle-carrying support 200 has a trumpet-shaped mesh structure, while the other parts of the particle-carrying support 200 are in an expanded state.

[0055] Step 3, Pre-positioning: Move the outer tube 102 toward the far end of the inner tube 101 until the particle chamber on the particle-carrying support 200 is outside the far end of the outer tube 102. During this process, the support recovery tube 108 moves toward the end of the particle-carrying support 200 that is in an expanded state and causes the corresponding part of the particle-carrying support 200 that passes through the support recovery tube 108 to retract inward and enter the first inner cavity 105 of the outer tube 102.

[0056] Step 4: Fill the support frame: such as Figure 14 As shown, a particle implanter 300 is used to load radioactive particles into the particle chamber on the particle-carrying scaffold 200.

[0057] Step 5, Retrieve the Support: Move the outer tube 102 toward the distal end of the inner tube 101 until the particle-carrying support 200 is in a fully retracted state and accommodated within the support receiving cavity 106, as shown below. Figure 10As shown. After the stent is retrieved and before the stent is implanted into the body, the stent retrieval tube 108 is removed from the delivery system 100.

[0058] Step 6: Release the stent: Move the outer tube 102 toward the proximal end of the inner tube 101 until the stent receiving cavity 106 is completely open circumferentially. During this process, the particle-carrying stent 200 is gradually and naturally released from the distal and proximal ends. Finally, the proximal end of the particle-carrying stent 200 is disengaged from the anchor 107, thereby releasing the particle-carrying stent 200 to the implantation area.

[0059] Compared to existing technologies that involve first loading particles onto a released particle-carrying stent and then manually squeezing the stent segment by segment before it enters the outer tube for retrieval, this application eliminates the need for the operator to directly contact the stent loaded with radioactive particles during the retrieval process. Therefore, this application helps reduce the radiation risk to the operator from radioactive particles. Furthermore, in this application, due to the stent retrieval tube, the corresponding segments of the particle-carrying stent passing through the retrieval tube are guided inwards continuously and smoothly. This retrieval process is more convenient and faster than the existing segment-by-segment manual squeezing process, improving surgical efficiency and safety, and saving surgical time.

[0060] Compared to existing technologies that involve manually squeezing radioactive particles into the implanter, the particle-carrying stent delivery system provided in this application makes it easier to retrieve and release the stent and reduces the risk of radiation exposure to the operator.

[0061] This invention provides a concept and method for a particle-carrying scaffold delivery system. Many methods and approaches exist for implementing this technical solution; the above description is merely a preferred embodiment. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of this invention, and these improvements and modifications should also be considered within the scope of protection of this invention. All components not explicitly stated in this embodiment can be implemented using existing technologies.

Claims

1. A particle-carrying scaffold delivery system, characterized in that, The delivery system (100) includes an inner tube (101) and an outer tube (102); the outer tube (102) includes a proximal end opening (103), a distal end opening (104), and a first inner cavity (105) extending from its proximal end opening (103) to its distal end opening (104); the inner tube (101) is slidably fitted within the first inner cavity (105) of the outer tube (102); a support receiving cavity (106) for accommodating a particle-carrying support (200) in a retracted state is formed between the distal section of the inner tube (101) and the sidewall of the first inner cavity (105) of the outer tube (102); the system also includes an anchor (107) and a support recovery tube (108), the anchor (107) being fixedly connected to the inner tube (101) and located at... Within the stent receiving cavity (106), the anchor (107) is used to connect with the proximal end of the particle-carrying stent (200) during the retrieval process and to disengage from the proximal end of the particle-carrying stent (200) during the release process; the stent retrieval tube (108) is detachably connected to the distal end of the outer tube (102) and communicates internally with the first inner cavity (105) of the outer tube (102); when the outer tube (102) moves toward the distal end of the inner tube (101), the stent retrieval tube (108) moves toward the expanded end of the particle-carrying stent (200) and causes the corresponding segment of the particle-carrying stent (200) passing through the stent retrieval tube (108) to retract inward and enter the first inner cavity (105) of the outer tube (102); The process of recovering and releasing the loadable particle support (200) using the aforementioned loadable particle support delivery system is as follows: Step 1: Install the stent retrieval tube (108) at the distal end of the outer tube (102), and position the distal end of the outer tube (102) near the distal end of the inner tube (101) so that the stent receiving cavity (106) is in an open state. Step 2, Anchoring Support: The unloaded, expanded particle support (200) is fitted onto the outside of the support receiving cavity (106), and the proximal braided wire of the particle support (200) is hung on the anchor (107); at this time, the proximal section of the particle support (200) has a trumpet-shaped mesh structure, while the other parts of the particle support (200) are in an expanded state; Step 3, Pre-positioning: Move the outer tube (102) toward the far end of the inner tube (101) until the particle chamber on the particle-carrying support (200) is outside the far end of the outer tube (102). During this process, the support recovery tube (108) moves toward the end of the particle-carrying support (200) in the expanded state and causes the corresponding part of the particle-carrying support (200) passing through the support recovery tube (108) to retract inward and enter the first inner cavity (105) of the outer tube (102). Step 4, loading the stent: Radioactive particles are loaded into the particle compartment on the particle-carrying stent (200) using a particle implanter (300); Step 5, retrieve the stent: move the outer tube (102) toward the distal end of the inner tube (101) until the particle-carrying stent (200) is in a fully retracted state and accommodated in the stent accommodating cavity (106); after retrieving the stent and before implanting the stent into the body, remove the stent retrieval tube (108) from the delivery system (100); Step 6, release the stent: Move the outer tube (102) toward the proximal end of the inner tube (101) until the stent receiving cavity (106) is completely open in the circumference. During this process, the particle-carrying stent (200) is gradually and naturally released from the distal and proximal ends. Finally, the proximal end of the particle-carrying stent (200) is detached from the anchor (107), thereby releasing the particle-carrying stent (200) into the implantation area.

2. The particle-carrying support delivery system according to claim 1, characterized in that, The anchoring element (107) includes a collar (109) and a plurality of anchor posts (110). The collar (109) is fixedly sleeved on the inner tube (101). The anchor posts (110) are spaced apart along the circumference of the collar (109) at the proximal outer periphery of the collar (109). The outer peripheral sidewall of the collar (109) between two adjacent anchor posts (110) is recessed inward to form a groove (111). The groove (111) extends along the axial direction of the collar (109) and is used to accommodate the braided filaments at the proximal end of the particle support (200) in the retracted state.

3. The particle-carrying support delivery system according to claim 2, characterized in that, The support recovery tube (108) is an elastic sleeve structure, including a trumpet-shaped compression section (129), an annular recovery section (130) connected to the small end of the trumpet-shaped compression section (129) and communicating with the interior of the trumpet-shaped compression section (129), and a slit (131) penetrating the side wall of the support recovery tube (108); the annular recovery section (130) is inserted into the distal end opening (104) of the outer tube (102) and sleeved with the outer tube (102), and the connection between the annular recovery section (130) and the outer tube (102) is smoothly transitioned.

4. The particle-carrying support delivery system according to claim 3, characterized in that, The system includes a guide head (112) fixed to the distal end of the inner tube (101) and a developing ring (113) fixedly sleeved on the outside of the inner tube (101). The guide head (112), the inner tube (101), the developing ring (113) and the side wall of the first inner cavity (105) of the outer tube (102) enclose the support receiving cavity (106).

5. The particle-carrying support delivery system according to claim 4, characterized in that, It also includes a middle tube (114) and a middle tube fixing handle (115), wherein the middle tube (114) is sleeved between the outer tube (102) and the inner tube (101); the distal end of the middle tube (114) is fixedly connected to the imaging ring (113), and the proximal end is fixedly connected to the middle tube fixing handle (115).

6. The particle-carrying support delivery system according to claim 5, characterized in that, It also includes a booster tube (116) and an inner tube fixing handle (117), wherein the booster tube (116) is sleeved between the middle tube (114) and the inner tube (101); the distal end of the booster tube (116) extends into the outer tube (102).

7. A particle-carrying support delivery system according to any one of claims 4 to 6, characterized in that, It also includes a locking device (118) located between the distal end of the outer tube (102) and the distal end of the inner tube (101) for limiting the relative sliding of the inner tube (101) and the outer tube (102) in the axial direction.

8. The particle-carrying support delivery system according to claim 7, characterized in that, The locking device (118) includes a first locking connector (119) and a second locking connector (120). The first locking connector (119) is fixedly connected to the proximal end of the outer tube (102). The distal end of the inner tube (101) passes through the second locking connector (120) and the first locking connector (119) in sequence and extends into the first inner cavity (105) of the outer tube (102). The second locking connector (120) is rotatably sleeved on the outside of the inner tube (101). The first locking connector (119) includes a locking part in sequence along the radial direction. 121) and the first threaded connection (122), the second locking connector (120) includes a pressing part (123) that cooperates with the locking part (121) and a second threaded connection part (124) that cooperates with the first threaded connection part (122), the second locking connector (120) and the first locking connector (119) are screwed together by the first threaded connection part (122) and the second threaded connection part (124), the pressing part (123) is used to press the locking part (121) inward to hug the inner tube (101) during the screwing connection process.

9. A particle-carrying support delivery system according to claim 8, characterized in that, The first locking connector (119) includes a movable handle (125) and a locking clamp (126). The locking clamp (126) is fixedly connected to the movable handle (125) to achieve the fixed connection between the first locking connector (119) and the outer tube (102). The locking part (121) is the proximal section of the locking clamp (126), and the first threaded connection part (122) is an internal threaded section located at the proximal end of the movable handle (125). The second locking connector (120) is a locking sleeve. The second threaded connection part (124) is an external threaded section located at the distal end of the locking sleeve. The squeezing part (123) is an inclined surface located on the distal inner peripheral sidewall of the locking sleeve and inclined inward toward the proximal end. During the screwing process, the inclined surface presses against the proximal end of the locking clamp (126) and pulls inward to hug the inner tube (101).

10. A particle-carrying support delivery system according to claim 9, characterized in that, The guide head (112) has a guide hole (127); the inner tube (101) includes a proximal end opening (103), a distal end opening (104) and a second inner cavity (128) extending from its proximal end opening (103) to its distal end opening (104); the guide hole (127) of the guide head (112) and the second inner cavity (128) are connected to form a guide wire channel.

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