A living body secretion material measuring device

Abstract

The present application relates to a kind of life organism secretion material measuring device, including suction film, electrode detection component, capacitance digital conversion circuit (CDC), processing module;The suction film is used to suck the secretion material of life organism;The capacitance digital conversion circuit is coupled electrode detection component, for obtaining mutual capacitance when having secretion material on suction film by electrode detection component;The processing module is coupled capacitance digital conversion circuit, and processing module is used to obtain mutual capacitance when not having secretion material on suction film, and according to the content signal of the secretion material of life organism outputted by the two mutual capacitances obtained.

Description

TECHNICAL FIELD

[0001] The present application relates to the measurement of secreted substances of living organisms, in particular the measurement of the oil content secreted by the human skin. BACKGROUND

[0002] Traditional methods for detecting oil in the skin mostly use film measurement + optical measurement, using a film to absorb oil and then performing standard comparison by optical methods, such as US Patent 4,532,937, which discloses a microporous film adhered to the skin for absorbing sebum; US Patent 5,119,828 discloses a microporous hydrophobic polymer film that is opaque when the pores are filled with gaseous material, and becomes translucent when the pores are filled with sebum, and uses this characteristic to perform optical measurement; or German Patent DE29700324U1 discloses skin analysis evaluation by test film, etc.

[0003] The most commonly used device for skin oil detection in the beauty or medical fields on the market is the CK device, which also uses oil-absorbing paper + photoelectricity. Each operation requires the detection end to be inserted into another component for calibration (the oil measurement device is divided into two parts), then the end is contacted with the measured area for 30 seconds, and then inserted back into the other component for measurement. The operation is complex, the efficiency is low, and the skin oil content is indirectly reflected by the transmittance.

[0004] The actual measurement unit of epidermal oil content is micrograms per square centimeter (ug / cm2), and the CK device can only distinguish between 50-350 ug / cm2 in terms of oil content corresponding to the transmittance of the oil-absorbing paper, and can roughly divide different areas of the human body into three levels of little oil, normal, and much oil. The corresponding table is as follows:

[0005]

[0006] The characteristics of the oil-absorbing paper material and the area of the oil spread on the oil-absorbing paper both affect the transmittance, and there are many influencing factors in the corresponding relationship between the transmittance of the oil-absorbing paper and the oil content, and the requirements for the oil-absorbing paper (consumables) are relatively high, and a specific oil-absorbing paper is required. Therefore, neither the traditional technology nor the CK device can accurately establish a corresponding relationship between the measurement value and the oil content using the film + optical technology route, the fuzzy range is large, and theoretically there is no room for improvement in accuracy. SUMMARY

[0007] The present application is to improve the deficiencies of the prior art, and proposes a device for measuring secreted substances of living organisms.

[0008] The measuring device of the present application comprises a suction film, an electrode detection assembly, a capacitance-to-digital conversion circuit (CDC), and a processing module. The suction film is used to suck the secretion of a living organism. The capacitance-to-digital conversion circuit is coupled to the electrode detection assembly and is used to obtain the mutual capacitance when the suction film has the secretion. The processing module is coupled to the capacitance-to-digital conversion circuit and is used to obtain the mutual capacitance when the suction film does not have the secretion, and output the content signal of the secretion of the living organism according to the two mutual capacitances.

[0009] The measuring device of the present application can measure the content of various secretions of a living organism by mutual capacitance. Taking the measurement of the oil secreted by the skin as an example, the suction film is selected as an oil absorption paper. The mutual capacitance difference change caused by the direct oil amount is basically removed from the material factor of the oil absorption paper and is directly related to the amount of oil. The main components of the oil secreted by the surface of a living organism, especially the human face, are glycerol triester, fatty acid, phospholipid, inositol, and lipid cholesterol. The combined dielectric constant of most oils is between 3.04 and 3.2, and the main component of the oil absorption paper is PP with a dielectric constant of 2.3-2.6. According to the capacitance formula C=εS / d, it is known that the capacitance is proportional to the dielectric constant. It can be seen that the dielectric constant of the oil is basically about 30% larger than that of the oil absorption paper. Therefore, the capacitance increment change effect is more significant, and thus the oil content on the oil absorption paper can be accurately detected. In addition, the capacitance-to-digital conversion circuit (CDC) such as DAI 7142 and ADI 7147 is used to convert the measured capacitance value into a digital value by the method of charging and discharging the measured capacitance multiple times and comparing it with the reference capacitance in the delta-sigma modulation mode (see US Patent Number: 5,134,401). The measurement sensitivity of the capacitance can be improved to 1 ff level.

[0010] The measuring device of the present application can immediately and one-time feedback the oil content of the skin after the detection end contacts the measured area for a certain period of time. The device is simple, integrated, and low in cost.

[0011] For the mutual capacitance of the suction film with and without the secretion, there are three ways according to the time interval between the two mutual capacitances from far to near: (1) prior calibration; (2) time-sharing detection; and (3) simultaneous detection. The farther the time interval, the greater the difference in the measurement environment, which leads to a decrease in accuracy.

[0012] For a pre-calibrated scheme, the hardware setup of the measuring device also includes a measuring surface configured to indirectly contact the living organism via an absorption membrane; the electrode detection assembly is configured to include at least two first electrodes disposed on the measuring surface; the absorption membrane is placed on the measuring surface during measurement and located in the mutual capacitance detection space formed between the first electrodes; a capacitance-to-digital conversion circuit is coupled to each first electrode to obtain the first mutual capacitance between the first electrodes; and a processing module is coupled to the capacitance-to-digital conversion circuit. Based on the above hardware structure, mutual capacitance data when there is no secreted substance on the absorption membrane can be detected in advance and stored in the memory of the processing module as reference data. During detection, the first mutual capacitance after the absorption membrane absorbs the secreted substance is obtained through the first electrodes. The processing module outputs a signal indicating the content of the substance secreted by the living organism based on the reference data and the first mutual capacitance after the absorption membrane absorbs the secreted substance. For example, the reference data reflects the dielectric constant of the absorption membrane alone, and the mutual capacitance after the absorption membrane absorbs the secreted substance reflects the dielectric constant of both the absorption membrane and the secreted substance. The difference between the two can be used to highlight the secreted substance and thus detect its content by capacitance detection. For pre-calibrated schemes, since the time interval between obtaining the two mutual capacitances is relatively long, the interference caused by environmental changes will be greater.

[0013] For the time-division detection scheme, the same hardware structure is relied upon. Based on this, during detection, the device is first used for manual measurement (e.g., clicking a button) to measure the first mutual capacitance of the absorption membrane placed on the measuring surface before it absorbs secretions. Then, after the absorption membrane has been in contact with the living organism's surface for a period of time, the button is clicked again to measure the first mutual capacitance after the membrane has absorbed the secretions. The processing module outputs a signal indicating the content of the secreted substance based on the first mutual capacitance before and after absorption. In this scheme, because the time interval between the two mutual capacitances is short (on the order of seconds), interference from environmental changes is low. Furthermore, the common-mode interference of the environment (Cmutual capacitance after absorption) can be subtracted, for example, by subtracting the difference between the two mutual capacitances. aw 2+C 环境共模干扰 - Mutual capacitance C before absorption aw 1+C 环境共模干扰 This allows for more accurate detection results.

[0014] For the simultaneous detection scheme, on the basis of the above hardware structure, a non-measurement surface is further provided for non-contacting the film and the living body during the measurement; the electrode detection assembly is configured to further include at least two second electrodes provided on the non-measurement surface; the film is synchronously arranged on the non-measurement surface and located in a mutual-capacitance detection space formed between the second electrodes during the measurement; and a capacitance-digital conversion circuit is coupled with each second electrode for acquiring a second mutual capacitance between the second electrodes. In the above hardware structure, the second mutual capacitance is taken as the mutual capacitance when the film does not have the secretion substance, and the first mutual capacitance after the film absorbs the secretion substance is taken as the mutual capacitance when the film has the secretion substance, and the processing module outputs a content signal of the secretion substance secreted by the living body according to the second mutual capacitance and the first mutual capacitance after the film absorbs the secretion substance. In this scheme, the acquisition interval between the two capacitances reaches the near-simultaneous stage (millisecond level, depending on the chip sampling interval), which basically eliminates the environmental variation interference, and through the difference operation, the error of the environmental common-mode interference can be removed, and a more accurate detection is obtained. Since the two regions are detected simultaneously, to avoid the difference in shape and size of the electrodes (first electrodes and second electrodes) in the two regions leading to the introduction of electrode inherent interference caused by the difference after the difference, the shape and size of the electrodes in the two regions can be set to be consistent. However, in practice, it is basically impossible to achieve consistency in theory due to manufacturing process problems, and therefore, the content signal can be corrected according to the second mutual capacitance. Specifically, the correction method further includes: acquiring a first difference between the first mutual capacitance and the second mutual capacitance before the film absorbs the secretion substance; acquiring a second difference between the first mutual capacitance and the second mutual capacitance after the film absorbs the secretion substance; and the processing module outputs the content signal of the secretion substance secreted by the living body according to the difference between the first difference and the second difference. Before the film absorbs the secretion substance, there is no secretion substance on the film, and the first difference after subtraction reflects the electrode inherent interference, and after the film absorbs the secretion substance, the film on the two regions has the secretion substance and does not have the secretion substance, and the second difference after subtraction reflects the dielectric constant of the secretion substance and the electrode inherent interference. By subtracting the first difference from the second difference, the electrode inherent interference can be removed, and the dielectric constant of the secretion substance is obtained for detection. In this scheme, it is not necessary to ensure that the electrodes in the two regions must be consistent, the precision requirement of the electrodes is not strict, and the manufacturing cost can be reduced.

[0015] As an improved scheme, an insulating layer can be provided on the surface of each electrode to reduce the interference with the capacitance and protect the secretion substance from corroding the electrode.

[0016] As another improvement scheme, a tightening device can be provided on the measuring device to tighten the suction film during the measurement to make it tightly adhere to the corresponding surface. Further, the tightening device can be configured to include a fixed component provided on both sides of the measuring surface and a rotating shaft knob, the fixed component fixes one end of the suction film, the other end of the suction film passes through the shaft hole in the rotating shaft knob, and the suction film is tightened by rotating the rotating shaft and then being pulled by the knurl on the side wall of the rotating shaft, so that the tightening is realized. The fixed component is configured as a single-end spring compression fixed component. The single-end spring compression fixed component is easy to operate. The suction film can be taken out by applying force to the pressing wrench, and the suction film can be tightened by releasing the pressing wrench. In use, the suction film is put into the inlet from one end, the other end of the suction film is put into the inlet by the single-end spring compression fixed component, and the other end of the suction film passes through the shaft hole in the rotating shaft knob. The rotating shaft is rotated, the friction between the knurl on the side wall of the rotating shaft and the suction film is increased, and the tail end of the suction film is pulled tight. The electrode detection elastic component is pressed to the bottom limit, and the clamping needle is pushed into the internal tooth groove to fix it. The electrode detection component has a fixed pushing force on the suction film by the rebound force of the spring, so that the suction film is tightened.

[0017] As another improvement scheme, a capacitance-to-digital conversion circuit can also be provided to obtain a self-capacitance from the electrode detection component. The self-capacitance can reflect the distance of the suction film from the measured surface and thus reflect the tightness. At this time, the processing module can output a logic signal that the suction film is separated from the living organism according to the self-capacitance (by threshold comparison), and / or the processing module can correct the mutual capacitance obtained according to the self-capacitance to avoid interference due to different tightness.

[0018] As another improvement scheme, the distance between the electrodes (e.g. between the first electrodes) for detecting the mutual capacitance in the electrode detection component is configured to be between 0.05-0.5mm. The purpose is to control the height of the mutual capacitance electric field, so that when the suction film is placed on the measured surface, the electric field lines can just pass through the suction film but not pass through the top surface, so that the detection only obtains the dielectric of the substance in the suction film, avoids the introduction of air dielectric by the part that passes out, and improves the detection accuracy. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 A front view of a living organism secretion substance measuring device is shown;

[0020] Figure 2 A sectional view of a living organism secretion substance measuring device is shown;

[0021] Figure 3 A sectional view of an electrode assembly is shown;

[0022] Figure 4 A sectional view of a rotating shaft tightening assembly and a spring compression assembly is shown.

[0023] Figure 5 A detection electrode distribution diagram is shown;

[0024] Figure 6 A detection electrode and a suction film stack structure diagram is shown. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application.

[0026] As shown in Figure 1 , 2 , 3, 4, 5, the life organism secretion measuring device comprises a lower cover 100, a suction film 140, an electrode detection assembly 110, a rotating shaft tensioning assembly 120, a spring pressing assembly 130, an upper cover 150, and a fastening bolt 160. The electrode detection assembly comprises a top head 111, an FPCA circuit assembly 112, a guide bolt 113, a spring 114, a cover support 115, a plastic bolt 116, a PFBA circuit assembly 117, and a circuit protection cover 118. The guide bolt 113 passes through the top head 111 and the spring 114 and is screwed with the lower cover 100 in a threaded manner, is limited by the top head 111 and the lower cover 100 in a slot 0-5, and is prevented from being deflected. One end of the FPCA circuit assembly 112 is attached to the side of the top head 111, and electrodes 1-1 and 1-2 are respectively attached to the top surface and the side surface of the top head 111 to prevent the electrodes from being warped due to the bending stress of the FPC soft board. The electrode ends extend out of the ears, the plastic bolt 116 passes through the electrode end ears and the top head 111 in a threaded manner, and is screwed. The other end of the FPCA circuit assembly is welded with the PCBA short circuit assembly 117, is positioned and assembled in the housing of the lower cover 100 through a hole column 1-3, and is clamped and tightened with the top head 111 through a buckle 1-4. The spring pressing assembly 130 comprises a guide bolt 131, a pressing piece 132, a spring 133, and a toothed block 134. The spring 133 is placed in a spring groove 3-1 of the toothed block 134, the toothed block 134 with the spring 133 is assembled and attached to the lower cover 100 through a tooth 0-4, and the guide bolt 131 passes through the pressing piece 132 and the side hole 0-6 of the lower cover 100 and is screwed with the toothed block 134 in a threaded manner. The rotating shaft tensioning assembly 120 comprises a clamping needle 121 and a rotating shaft 122. The rotating shaft 122 is assembled at a hole position 0-7 of the lower cover 100, the upper cover 150 is positioned and assembled with the lower cover 100 through a hole column 1-3, the top end of the rotating shaft 122 passes through a limiting hole 2-5 of the upper cover 150, the clamping needle 121 passes into the top side hole of the rotating shaft 122 through a guide groove 2-4, and the upper and lower covers are fixed and locked through the fastening bolt 160.

[0027] Test preparation: put the suction film 140 from the entrance 0-1, and fix one end of the suction film 140 by the spring compression assembly 130; the other end of the suction film 140 passes through the shaft hole 2-1 in the rotating shaft 122, and is put into the entrance 0-2 by the electrode detection assembly 110, and is fixed in the inner tooth groove 2-3 by rotating the clamping needle 121 to make the rotating shaft 122 rotate, and increasing the friction between the rotating shaft side wall knurl 2-2 and the suction film 140 to make it tight, until the electrode detection assembly 110 is pressed to the bottom limit 0-3, and then the clamping needle 121 is pushed into the inner tooth groove 2-3 to be fixed, so that the electrode detection assembly 110 has a fixed pushing force on the suction film 140 by the elastic force of the spring 114, so that the suction film 140 maintains a standard stretched state.

[0028] As shown in Figure 5 , the electrode detection assembly 110 includes a first electrode group 1-1 and a second electrode group 1-2, each of which is composed of two crossed comb electrodes, and the shapes of the two groups of electrodes are synchronous; the first electrode group includes electrodes C a1 , C a2 , configured as a first mutual capacitance C aw , and the second electrode group includes electrodes C b1 , C b2 , configured as a second mutual capacitance C bw .

[0029] As shown in Figure 5 , 6 , the first electrode group 1-1 contacts the living body and absorbs secretions, and the second electrode group 1-2 serves as a contrast reference to the first electrode group 1-1 and does not contact the living body; the electrode surface is covered with an insulating film, and the line width of the electrode and the spacing between the electrodes are both kept within the range of 0.05-0.5mm, so as to ensure that the mutual capacitance electric field covers various types and thicknesses of the suction film 140 but does not exceed the outer surface of the suction film; for the mutual capacitance with and without secretions on the suction film 140, the operation sequence is as follows:

[0030] Prior calibration measurement method: set that the suction film 140 is currently in a state of not absorbing secretions of the living body; at this time, start testing to obtain the first group of mutual capacitance values C aW 1, and set the first group of test mutual capacitance C aW 1 as the reference data; then, the living body approaches and contacts the first electrode group 1-1, at this time, the surface suction film 140 is fused and absorbed with the secretions of the living body, and sets the contact time to end, at this time, the suction film 140 has absorbed the secretions of the living body, and again tests to obtain the second group of mutual capacitance values C aw 2, C aw 2 and C aWThe difference between C aw 1 is taken as the contrast reference value.

[0031] The time-sharing detection method is as follows: it is set that the absorption film 140 is in a state of not absorbing the secretion of the living organism; at this time, the first group of mutual capacitance values C aW 1 is obtained by testing; then the living organism approaches and contacts the first electrode group 1-1; at this time, the surface absorption film 140 is fused and absorbed with the secretion of the living organism; it is set that the contact time ends and then the living organism leaves; at this time, the absorption film 140 has absorbed the secretion of the living organism; the second group of mutual capacitance values C aw 2 is obtained by testing; the difference between C aw 2 and C aW 1 is taken as the capacitance value result of the secretion in the absorption film; the subsequent replacement of the absorption film 140 needs to be synchronized with the above operation steps.

[0032] The simultaneous detection method is as follows: it is set that the absorption film 140 is in a state of not absorbing the secretion of the living organism; at this time, the living organism directly approaches and contacts the first electrode group 1-1; at this time, the surface absorption film 140 is fused and absorbed with the secretion of the living organism; it is set that the contact time ends and then the living organism leaves; the first group of mutual capacitance values C aW 1 is obtained by testing; C bW 1 is obtained by testing; the difference between C aw 1 and C bW 1 is taken as the capacitance value result of the secretion in the absorption film; the subsequent replacement of the absorption film 140 needs to be synchronized with the above operation steps.

[0033] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, and are not intended to limit the protection scope of the present application. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present application.

Claims

1. A device for measuring substances secreted by a living organism, characterized in that: Includes an absorption membrane, electrode detection assembly, capacitance-to-digital conversion circuit, and processing module; The absorbent membrane is used to absorb secretions from a living organism, wherein the secretions are configured as oils, and the absorbent membrane is configured as oil-absorbing paper. The capacitance-to-digital conversion circuit is coupled to the electrode detection component and is used to obtain the mutual capacitance of the absorption membrane when there is no secreted substance on the electrode detection component. The processing module is coupled to the capacitance-to-digital conversion circuit. The processing module is used to obtain the mutual capacitance when the absorbent membrane does not contain the secreted substance, and to obtain the mutual capacitance after the absorbent membrane absorbs the secreted substance from the organism and leaves the organism. Based on the difference between the two obtained mutual capacitances, the processing module outputs a signal indicating the content of the secreted substance from the organism.

2. The measuring device for secreted substances in living organisms according to claim 1, characterized in that: It also includes a measuring surface configured to indirectly contact a living organism via the absorption membrane; The electrode detection assembly is configured to include at least two first electrodes disposed on the measurement surface; The absorption membrane is placed on the measurement surface and located in the mutual capacitance detection space formed between the first electrodes during the measurement. The capacitance-to-digital conversion circuit is coupled to each of the first electrodes to obtain the first mutual capacitance between the first electrodes. The processing module is coupled to the capacitor-to-digital converter circuit.

3. The measuring device for secreted substances in living organisms according to claim 2, characterized in that: The first mutual capacitance before the absorption membrane absorbs the secreted material is taken as the mutual capacitance when the absorption membrane does not have the secreted material. The first mutual capacitance after the absorption membrane absorbs the secreted material is taken as the mutual capacitance when the absorption membrane has the secreted material. The processing module outputs a signal indicating the content of substances secreted by the living organism based on the first mutual capacitance before and after the absorptive membrane absorbs the secreted substances.

4. The measuring device for secreted substances in living organisms according to claim 2, characterized in that: The mutual capacitance on the aspiration membrane when there is no secreted material is detected in advance and stored in the memory of the processing module as reference data. The first mutual capacitance after the absorption membrane absorbs the secreted material is taken as the mutual capacitance when the absorption membrane has the secreted material. The processing module outputs a signal indicating the content of substances secreted by the living organism based on the reference data and the first mutual capacitance after the aspirating membrane absorbs the secreted substances.

5. The measuring device for secreted substances in living organisms according to claim 2, characterized in that: The device for measuring secretions of living organisms also has a non-measuring surface, which is used to ensure that the membrane does not come into contact with the living organism during the measurement. The electrode detection assembly is configured to include at least two second electrodes disposed on the non-measuring surface; The absorption membrane is synchronously placed on the non-measuring surface and located in the mutual capacitance detection space formed between the second electrodes during the measurement. The capacitance-to-digital conversion circuit is coupled to each of the second electrodes to obtain the second mutual capacitance between the second electrodes.

6. The measuring device for secreted substances in living organisms according to claim 5, characterized in that: The second mutual capacitance is used as the mutual capacitance when the absorbent membrane does not contain the secreted substance. The first mutual capacitance after the absorption membrane absorbs the secreted material is taken as the mutual capacitance when the absorption membrane has the secreted material. The processing module outputs a signal indicating the content of substances secreted by the living organism based on the second mutual capacitance and the first mutual capacitance after the absorption membrane absorbs the secreted substances.

7. The measuring device for secreted substances of living organisms according to claim 6, characterized in that: The processing module corrects the content signal based on the second mutual capacitance.

8. The measuring device for secreted substances in living organisms according to claim 7, characterized in that, The correction method further includes: Before the aspirating membrane absorbs the secreted material, the first difference between the first mutual capacitance and the second mutual capacitance is obtained; After the aspirating membrane absorbs the secreted material, a second difference between the first mutual capacitance and the second mutual capacitance is obtained; The processing module outputs a signal indicating the content of substances secreted by the living organism based on the difference between the first difference and the second difference.

9. The measuring device for secreted substances of living organisms according to claim 2 or 5, characterized in that: An insulating layer is provided on the surface of each electrode.

10. The measuring device for secreted substances of living organisms according to claim 2 or 5, characterized in that: It also includes a tightening device for tautling the absorbent membrane during measurement so that it adheres tightly to the corresponding surface.

11. The measuring device for secreted substances in living organisms according to claim 10, characterized in that: The tightening device includes a fixing component and a rotating shaft knob respectively located on both sides of the measuring surface. The fixing component fixes one end of the suction membrane, and the other end of the suction membrane passes through the shaft hole in the rotating shaft knob. After rotating the rotating shaft, the membrane is tightened by the knurling on the side wall of the rotating shaft.

12. The measuring device for secreted substances in living organisms according to claim 11, characterized in that: The fixing component is configured as a single-end spring-loaded fixing component.

13. The measuring device for secreted substances in living organisms according to claim 1, characterized in that: The capacitance-to-digital conversion circuit is also used to obtain the capacitance via the electrode detection component; The processing module is used to output a logic signal for the absorption membrane to detach from the organism based on the self-capacitance, and / or to correct the acquired mutual capacitance based on the self-capacitance.

Images