A refreshing stable high-multiple sunscreen cream and a preparation method thereof

Abstract

The application provides a kind of refreshing stable high multiple sunscreen cream and its preparation method, the component of the refreshing stable high multiple sunscreen cream includes chemical sunscreen agent, physical sunscreen agent, emulsifier, oil, humectant, deionized water;The chemical sunscreen agent is the combination of ethylhexyl methoxy cinnamate, diethyl amino hydroxy benzoyl hexyl benzoate, methylene bis-benzotriazolyl tetramethyl butyl phenol.The sunscreen cream of the application selects the safe component without irritation, by combining physical sunscreen agent and chemical sunscreen agent, the two are used in conjunction, can better strengthen skin barrier, can protect facial skin from the invasion of effective ultraviolet radiation, and then reach the significant sunscreen effect, meanwhile, the oil, emulsifier and humectant selected in the sunscreen cream component not only can keep better system compatibility, but also can further improve the defense ability of skin.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of cosmetics, and particularly relates to a light and stable high-factor sunscreen cream and a preparation method thereof. BACKGROUND

[0002] Ultraviolet rays are an important inducement to accelerate skin aging, and appropriate sun protection measures can effectively delay skin aging. Currently, the sunscreens on the market mainly use physical protection, chemical protection or a combination of physical and chemical protection to absorb ultraviolet rays. In order to achieve better sun protection, consumers are increasingly inclined to use high-factor sunscreen products. Therefore, in order to obtain high-factor sunscreen products, more and more products increase the amount of sunscreen added in the components, which can effectively increase the sun protection factor.

[0003] CN109498474A discloses a light three-phase emulsified sunscreen cosmetic and a preparation method thereof. The components include oil, surfactant, polyol, sunscreen, thickening agent and water. The oil includes seven substances such as dicaprylyl carbonate and isononyl isononanoate, the surfactant includes four substances such as PEG-10 dimethicone, the polyol includes six substances such as glycerol and sorbitol, the sunscreen includes six substances such as titanium dioxide and octocrylene, and the thickening agent includes three substances such as sodium polyacrylate.

[0004] CN108670890A discloses an organic sunscreen composition and application thereof. The organic sunscreen composition is prepared from the following raw materials: ethylhexyl methoxy cinnamate, C12-15 alcohol benzoate, isopropyl lauroyl sarcosinate, octocrylene, bis-ethylhexyloxyphenol methoxyphenyl triazine, octyl trimethylsiloxane, ethylhexyl triazone, diethylamino hydroxybenzoyl hexyl benzoate, isodecyl neopentanoate and butyl methoxydibenzoylmethane. The above-mentioned organic sunscreen composition includes different waveband ultraviolet absorbers, which can achieve good sunscreen effect, have good compatibility and high lightness, and the sunscreen product containing the composition can protect the skin and bring a pleasant skin feel. The organic sunscreen composition can be applied in cosmetics or skin care products, such as sunscreen jelly, sunscreen spray, sunscreen cream, color cosmetics with sunscreen effect and various dosage forms.

[0005] However, the use of too much sunscreen in the above-mentioned products will cause greasy skin feel and skin whitening, which affects the sensory experience of the product. Therefore, it is of great market value to provide a high-factor sunscreen product with lightness. SUMMARY

[0006] In view of the deficiencies of the prior art, the present application aims to provide a refreshing and stable high-multiple sunscreen cream and a preparation method thereof, which can not only ensure the sunscreen effect of the product, but also make the product have a refreshing and non-greasy application feeling.

[0007] To achieve the object of the present application, the following technical solutions are adopted:

[0008] In a first aspect, the present application provides a refreshing and stable high-multiple sunscreen cream, the components of which include chemical sunscreen agents, physical sunscreen agents, emulsifiers, oils, moisturizers, and deionized water.

[0009] The chemical sunscreen agents are a combination of ethylhexyl methoxy cinnamate, diethyl amino hydroxybenzoyl hexyl benzoate, and methylene bis-benzotriazolyl tetramethylbutylphenol.

[0010] The components of the sunscreen cream of the present application are safe and non-irritating. By combining physical sunscreen agents and chemical sunscreen agents, the two can be used together to better strengthen the skin barrier, protect the facial skin from the invasion of ultraviolet radiation, and thus achieve a significant sunscreen effect. In addition, the use of oils, emulsifiers, and moisturizers in the components of the sunscreen cream not only ensures better system compatibility, but also further improves the skin's defense ability. The use of oils with strong dispersibility and good compatibility can reduce the amount of emulsifiers used, thereby reducing the heavy feeling and possible irritation of high emulsifiers. The use of multiple polyols can reduce the sticky feeling caused by a single component or the irritation caused by a high amount of a single component, while also having moisturizing properties. In addition, the use of ethylhexyl methoxy cinnamate (UVB), diethyl amino hydroxybenzoyl hexyl benzoate (UVA), and methylene bis-benzotriazolyl tetramethylbutylphenol (UVA+UVB) in the chemical sunscreen agents of the present application has a synergistic effect, covering all bands of ultraviolet light. This can ensure high SPF and PFA values while effectively reducing the greasy feeling of the sunscreen cream, making the product have a refreshing and moisturizing skin feel after use.

[0011] Preferably, the mass ratio of ethylhexyl methoxy cinnamate, diethyl amino hydroxybenzoyl hexyl benzoate, and methylene bis-benzotriazolyl tetramethylbutylphenol is (1-10):(0.2-8):(0.5-10).

[0012] Wherein "1-10" can be 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5, 8.5, 9, or 9.5, etc.

[0013] "0.2-8" can be 0.5, 0.8, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, or 7.5, etc.

[0014] "0.5-10" can be 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5, 8.5, 9 or 9.5, etc.

[0015] Preferably, the physical sunscreen agent comprises titanium dioxide and / or zinc oxide.

[0016] The physical sunscreen agent of the present application is selected from titanium dioxide and / or zinc oxide, both of which have good reflection and scattering effects on ultraviolet rays, thereby achieving the effect of shielding ultraviolet rays.

[0017] Preferably, the emulsifier comprises any one or a combination of at least two of PEG-2 stearate, PEG-20 stearate, glyceryl stearate, potassium lauryl phosphate, sorbitan stearate, polyglyceryl-3 isostearate, methyl gluceth-20, isocetyl polyoxyl-20, cetyl stearyl alcohol or C20-22 alcohol phosphate.

[0018] Preferably, the oil comprises any one or a combination of at least two of cyclopentasiloxane, dimethicone, butylene glycol dicaprylate / dicaprate, neopentyl glycol diheptanoate, oleic acid / linoleic acid / linolenic acid polyglyceryl esters, hydroxystearic acid or squalane.

[0019] Preferably, the moisturizing agent comprises any one or a combination of at least two of 1,3-propanediol, diglycerol, glucose, 1,2-hexanediol, sodium hyaluronate or butylene glycol.

[0020] Preferably, the light and stable high-multiple sunscreen cream further comprises a plant sunscreen agent.

[0021] Preferably, the plant sunscreen agent comprises a Laminaria ochotensis extract and / or ergothioneine.

[0022] Preferably, the plant sunscreen agent is a combination of the Laminaria ochotensis extract and the ergothioneine.

[0023] As a preferred technical solution of the present application, the Laminaria ochotensis extract acts as an ultraviolet filter, can improve the skin's tolerance to ultraviolet rays, prevent photoaging, and at the same time soothe sunburned skin and reduce wrinkles; the ergothioneine can scavenge free radicals, regulate the oxidation-reduction reaction in cells, alleviate the damage of ultraviolet rays to the skin, participate in the regulation of intracellular energy and physiological protection of cells, and the combination of the two as a plant sunscreen agent can further improve the sunscreen ability of the sunscreen cream.

[0024] Preferably, the mass ratio of the Laminaria ochotensis extract and the ergothioneine is 1:(1-2), which can be 1:1.1, 1:1.2, 1:1.3, 1:1.4, 1:1.5, 1:1.6, 1:1.7, 1:1.8 or 1:1.9, etc.

[0025] Preferably, the light-feeling stable high-factor sunscreen cream further comprises a skin feel modifier.

[0026] Preferably, the skin feel modifier comprises any one or a combination of at least two of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica.

[0027] Preferably, the skin feel modifier comprises a combination of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica.

[0028] As a preferred technical solution of the present application, the skin feel modifier is a combination of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica, which are used in combination, not only increasing the system stability of the sunscreen cream, but also further enhancing the light-feeling experience after use.

[0029] Preferably, the mass ratio of the glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica is (1-3):(0.5-1.5):(0.1-1).

[0030] wherein "1-3" can be 1.2, 1.5, 1.8, 2, 2.2, 2.5, or 2.8, etc.

[0031] "0.5-1.5" can be 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, or 1.5, etc.

[0032] "0.1-1" can be 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, or 0.9, etc.

[0033] Preferably, the light-feeling stable high-factor sunscreen cream further comprises a thickening agent and / or a chelating agent.

[0034] Preferably, the thickening agent comprises acrylates / ethylhexyl decylcro s poly mer and / or xanthan gum.

[0035] Preferably, the chelating agent comprises disodium EDTA.

[0036] Preferably, the light-feeling stable high-factor sunscreen cream further comprises any one or a combination of at least two of a preservative, a pH adjuster, or a fragrance.

[0037] Preferably, the components of the light and stable high-multiple sunscreen lotion include 1-30 parts of chemical sunscreen agent, 1-10 parts of physical sunscreen agent, 1-10 parts of emulsifier, 1-15 parts of oil, 1-15 parts of moisturizing agent, and 30-99 parts of deionized water.

[0038] The addition amount of the chemical sunscreen agent in the light and stable high-multiple sunscreen lotion of the present application can be 3 parts, 6 parts, 9 parts, 10 parts, 12 parts, 15 parts, 18 parts, 20 parts, 23 parts, 25 parts, or 28 parts, etc.

[0039] The addition amount of the physical sunscreen agent can be 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, or 9 parts, etc.

[0040] The addition amount of the emulsifier can be 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, or 9 parts, etc.

[0041] The addition amount of the oil can be 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, or 14 parts, etc.

[0042] The addition amount of the moisturizing agent can be 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, or 14 parts, etc.

[0043] The addition amount of the deionized water can be 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts, 75 parts, 80 parts, 85 parts, 90 parts, or 95 parts, etc.

[0044] Preferably, the components of the light and stable high-multiple sunscreen lotion include 1-20 parts of chemical sunscreen agent, 1-8 parts of physical sunscreen agent, 1-8 parts of plant sunscreen agent, 1-8 parts of emulsifier, 1-10 parts of oil, 1-10 parts of moisturizing agent, 1-5 parts of skin feel regulator, 0.1-1 parts of thickening agent, 0.05-0.2 parts of chelating agent, and 30-99 parts of deionized water.

[0045] The addition amount of the skin feel regulator in the light and stable high-multiple sunscreen lotion of the present application can be 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, or 4.5 parts, etc.

[0046] The addition amount of the thickening agent can be 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.

[0047] The addition amount of the chelating agent can be 0.06 parts, 0.08 parts, 0.1 parts, 0.12 parts, 0.14 parts, 0.15 parts, 0.17 parts, or 0.19 parts, etc.

[0048] Other specific point values within each of the above ranges of values can be selected, which will not be repeated here.

[0049] In a second aspect, the present application provides a preparation method of the light and stable high-multiple sunscreen cream as described in the first aspect, which comprises mixing and homogenizing the chemical sunscreen agent, the physical sunscreen agent, the emulsifier, the oil, the humectant and the deionized water, to obtain the light and stable high-multiple sunscreen cream.

[0050] Preferably, the method comprises:

[0051] (1) mixing part of the chemical sunscreen agent, the emulsifier, the oil, part of the skin feel regulator, the physical sunscreen agent, heating to 75-85℃ (for example, it can be 76℃, 78℃, 80℃, 82℃ or 84℃, etc.), to obtain phase A;

[0052] (2) mixing the chelating agent, the thickening agent, part of the humectant, the remaining skin feel regulator, half of the amount of water, heating to 75-85℃ (for example, it can be 76℃, 78℃, 80℃, 82℃ or 84℃, etc.), to obtain phase B;

[0053] (3) mixing the remaining chemical sunscreen agent and the remaining water, to obtain phase C;

[0054] (4) mixing and homogenizing phase A and phase B, adding phase C and homogenizing, cooling to 45℃ (for example, it can be 25℃, 28℃, 30℃, 32℃, 35℃ or 38℃, etc.), adding the remaining humectant, the plant sunscreen agent, mixing and homogenizing, to obtain the sunscreen cream;

[0055] The steps (1), (2) and (3) are not distinguished in the order.

[0056] Preferably, after adding the plant sunscreen agent in step (4), it further comprises adding any one or a combination of at least two of the preservative, the pH regulator or the fragrance.

[0057] Other specific point values within each of the above ranges of values can be selected, which will not be repeated here.

[0058] Compared with the prior art, the present application has the following beneficial effects:

[0059] (1) The components selected for the sunscreen cream of the present application are safe and non-irritating, and through the combination of the physical sunscreen agent and the chemical sunscreen agent, the two are used in combination, which can better strengthen the skin barrier, protect the facial skin from the invasion of ultraviolet radiation, and thus achieve a significant sunscreen effect. At the same time, the selection of the oil, the emulsifier and the humectant in the components of the sunscreen cream not only can maintain better system compatibility, but also can further improve the defense ability of the skin.

[0060] (2) The chemical sunscreen agent in the present application uses ethylhexyl methoxy cinnamate, diethylamino hydroxybenzoyl hexyl benzoate and methylene bis-benzotriazolyl tetramethylbutylphenol in combination, the three have synergistic effect, can effectively reduce the greasy feeling of sunscreen cream while ensuring high SPF value and PFA value, so that the product has a refreshing and moisturizing skin feel after use.

[0061] (3) The preparation method of the sunscreen cream provided by the present application is simple, easy to operate in the production process, does not require complex instruments and equipment, and does not require harsh production conditions, and is easy to industrialize. DETAILED DESCRIPTION

[0062] The technical solutions of the present application are further illustrated by specific embodiments. Those skilled in the art should understand that the embodiments are only to help understand the present application and should not be regarded as specific limitations on the present application.

[0063] The specification information of some raw materials involved in the following examples and comparative examples is as follows:

[0064]

[0065] The remaining raw materials can be used as long as they are purchased from regular dealers.

[0066] Example 1

[0067] The present embodiment provides a refreshing and stable high-multiple sunscreen cream, and the formula is as follows:

[0068]

[0069]

[0070] The preparation method of the refreshing and stable high-multiple sunscreen cream is as follows:

[0071] (1) Mix potassium lauryl phosphate, methyl gluceth-20, isocetyl alcohol polyether-20, butylene glycol dicaprylate / dicaprate, dimethicone, ethylhexyl methoxy cinnamate, diethylamino hydroxybenzoyl hexyl benzoate, titanium dioxide, zinc oxide, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica, heat to 80℃, to obtain phase A;

[0072] (2) Mix disodium EDTA, acrylates / ethylene vinyl decanoate crosspolymer, glycerol polymethacrylate, 1,3 propanediol, diglycerol, and half the amount of water, heat to 75℃, to obtain phase B;

[0073] (3) Mix methylene bis-benzotriazolyl tetramethylbutylphenol and the remaining water to obtain phase C;

[0074] (4) the A phase and the B phase are mixed and homogenized, the C phase is added and homogenized, the temperature is lowered to 40°C, glycerin, kelp extract, and ergothioneine are added and homogenized, to obtain the sunscreen cream.

[0075] Example 2

[0076] This example provides a refreshing and stable high-multiple sunscreen cream, whose formula is as follows:

[0077]

[0078]

[0079] The preparation method of the refreshing and stable high-multiple sunscreen cream is as follows:

[0080] (1) PEG-2 stearate, PEG-20 stearate, sorbitan stearate, neopentyl glycol diheptanoate, cyclopentasiloxane, methoxyethyl salicylate, diethylhexyl 2,6-naphthalate, titanium dioxide, zinc oxide, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica are mixed and heated to 75°C to obtain the A phase;

[0081] (2) disodium EDTA, acrylates / ethylhexyl decylal crosspolymer, glycerin polymethacrylate, diglycerin, sodium hyaluronate, and half the amount of water are mixed and heated to 85°C to obtain the B phase;

[0082] (3) methylene bis-benzotriazolyl tetramethylbutylphenol and the remaining water are mixed to obtain the C phase;

[0083] (4) the A phase and the B phase are mixed and homogenized, the C phase is added and homogenized, the temperature is lowered to 35°C, butanediol, kelp extract, and ergothioneine are added and homogenized, to obtain the sunscreen cream.

[0084] Example 3

[0085] This example provides a refreshing and stable high-multiple sunscreen cream, whose formula is as follows:

[0086]

[0087]

[0088] The preparation method of the refreshing and stable high-multiple sunscreen cream is as follows:

[0089] (1) ethylhexyl methoxy cinnamate, oxybenzone, methyl glucose ether-20, sorbitan stearate, polyglyceryl-3 isostearate, potassium lauryl phosphate, squalane, dimethicone, butylene glycol dicaprylate / dicaprate, vinyl dimethicone / methicone silsesquioxane crosspolymer, silica, titanium dioxide mixed, heated to 75℃, to obtain phase A;

[0090] (2) disodium EDTA, acrylates / ethylhexyl dimethoxybenzylidenyl ketal crosspolymer, glyceryl polymethacrylate, butylene glycol, half amount of water mixed, heated to 85℃, to obtain phase B;

[0091] (3) methylene bis-benzotriazolyl tetramethylbutylphenol and water mixed, to obtain phase C;

[0092] (4) phase A and phase B are mixed and homogenized, phase C is added and homogenized, cooled to 35℃, glycerin, 1,2 pentanediol, ecklonia extract, ergothioneine are mixed and homogenized, to obtain the sunscreen cream.

[0093] Example 4

[0094] This example provides a refreshing stable high multiple sunscreen cream, which is only different from example 1 in that the plant sunscreen agent is not contained in the components, the reduced amount is supplemented by water, and the rest of the components remain unchanged, and the preparation method refers to example 1.

[0095] Example 5

[0096] This example provides a refreshing stable high multiple sunscreen cream, which is only different from example 1 in that the plant sunscreen agent in the components is ecklonia extract 5 parts, and the rest of the components remain unchanged, and the preparation method refers to example 1.

[0097] Example 6

[0098] This example provides a refreshing stable high multiple sunscreen cream, which is only different from example 1 in that the plant sunscreen agent in the components is ergothioneine 5 parts, and the rest of the components remain unchanged, and the preparation method refers to example 1.

[0099] Example 7

[0100] This example provides a refreshing stable high multiple sunscreen cream, which is only different from example 1 in that the skin feel regulator is not contained in the components, the content is supplemented by water, and the rest of the components remain unchanged, and the preparation method refers to example 1.

[0101] Example 8

[0102] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the skin feel modifier in the composition does not include glycerin polymethyl methacrylate, and the reduced amount of glycerin polymethyl methacrylate is proportionally distributed to the vinyl dimethicone / methicone silsesquioxane crosspolymer and the silica, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0103] Example 9

[0104] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the skin feel modifier in the composition does not include the vinyl dimethicone / methicone silsesquioxane crosspolymer, and the reduced amount of vinyl dimethicone / methicone silsesquioxane crosspolymer is proportionally distributed to the glycerin polymethyl methacrylate and the silica, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0105] Example 10

[0106] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the skin feel modifier in the composition does not include the silica, and the reduced amount of silica is proportionally distributed to the glycerin polymethyl methacrylate and the vinyl dimethicone / methicone silsesquioxane crosspolymer, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0107] Comparative Example 1

[0108] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the composition does not contain physical sunscreen agents, and the reduced amount is made up by chemical sunscreen agents, and the proportion of each component of the chemical sunscreen agents is unchanged, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0109] Comparative Example 2

[0110] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the composition does not contain chemical sunscreen agents, and the reduced amount is made up by physical sunscreen agents, and the proportion of each component of the physical sunscreen agents is unchanged, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0111] Comparative Example 3

[0112] The present example provides a light and stable high factor sunscreen cream, which differs from example 1 only in that the chemical sunscreen agent in the composition does not include ethylhexyl methoxyphenyl triazine, and the reduced amount of ethylhexyl methoxyphenyl triazine is proportionally distributed to the dioctyl hydroxylbenzoyl hexyl benzoate and methylene bis-benzotriazolyl tetramethylbutylphenol, and the remaining components remain unchanged, and the preparation method is referred to example 1.

[0113] Comparative Example 4

[0114] This example provides a refreshing stable high multiple sunscreen cream, which is only different from Example 1 in that the chemical sunscreen agent in the component does not include diethylamino hydroxybenzoyl hexyl benzoate, and the reduced amount is distributed to ethylhexyl methoxy cinnamate and methylene bis-benzotriazolyl tetramethyl butyl phenol in the ratio of parts, and the rest of the components remain unchanged. The preparation method is referred to Example 1.

[0115] Comparative Example 5

[0116] This example provides a refreshing stable high multiple sunscreen cream, which is only different from Example 1 in that the chemical sunscreen agent in the component does not include methylene bis-benzotriazolyl tetramethyl butyl phenol, and the reduced amount is distributed to ethylhexyl methoxy cinnamate and diethylamino hydroxybenzoyl hexyl benzoate in the ratio of parts, and the rest of the components remain unchanged. The preparation method is referred to Example 1.

[0117] Test Example 1 Sunscreen Effect Evaluation

[0118] Sunscreen creams made according to Examples 1-10 and Comparative Examples 1-5 were subjected to sunscreen effect evaluation tests, according to the Sunscreen Index Test Method (Human Method) for Sunscreen Cosmetics in the Cosmetic Safety Technical Specification (2015 Edition), to test the sunscreen effect of the products, with the sunscreen index (SPF value) and the long-wave ultraviolet protection index (PFA value) for sunscreen cosmetics as evaluation indicators.

[0119] SPF, also known as the sunlight protection coefficient, indicates the level of sunscreen effectiveness that sunscreen products can exert. The larger the SPF value, the better the protection effect against UVB. It is determined according to the minimum erythema dose (MED) of the skin. After using sunscreen products, the minimum erythema dose of the skin will increase, and the sunscreen factor SPF of the sunscreen product will be:

[0120] SPF value = MED of skin protected by sunscreen cosmetics / MED of unprotected skin

[0121] PFA, also known as UVA protection index. UVA in sunlight irradiates the skin, mainly producing physiological effects of skin darkening, which is measured by the minimum persistent pigmentation dose (MPPD). MPPD is the minimum ultraviolet radiation dose or shortest irradiation time required to produce slight darkening on the entire irradiated skin 2-4 hours after irradiation. The PFA of the sunscreen product is:

[0122] PFA value = MPPD of skin protected by sunscreen cosmetics / MPPD of unprotected skin

[0123] The results of the sunscreen effect test are shown in Table 1:

[0124] Table 1

[0125] Sample name SPF value PFA value Example 1 54 13 Example 2 52 11 Example 3 51 11 Example 4 39 6 Example 5 43 8 Example 6 44 7 Example 7 53 13 Example 8 54 12 Example 9 53 11 Example 10 53 12 Comparative Example 1 48 10 Comparative Example 2 52 12 Comparative Example 3 42 11 Comparative Example 4 53 7 Comparative Example 5 39 6

[0126] From Table 1, the SPF values of the sunscreen creams of Examples 1-3 are 51-54, and the PFA values are 11-13, indicating that the sunscreen creams of the present application have good sunscreen effect; in Example 4, when the plant sunscreen agent is absent, the SPF value and the PFA value of the sunscreen cream are reduced; in Examples 5-6, the Laminariales extract and the ergothioneine in the plant sunscreen agent have synergistic effect, and the absence of either of them will reduce the sunscreen effect of the sunscreen cream; in Comparative Examples 1-2, when the chemical sunscreen agent or the physical sunscreen agent is absent, although the sunscreen ability of the sunscreen cream is not significantly reduced, the high amount of the chemical sunscreen agent has strong greasy feeling, and the dryness after absorption is obvious, which is not conducive to subsequent makeup; and the high amount of the physical sunscreen agent makes the material difficult to spread, and the whitening is serious, affecting the sensory acceptability of the consumer. This can be reflected in the skin feel evaluation below; from Comparative Examples 3-5, it can be seen that the components in the chemical sunscreen agent can produce synergistic effect, which can better improve the sunscreen index of the sunscreen cream.

[0127] Test Example 2 Skin Feel Evaluation

[0128] 100 healthy female volunteers were selected and randomly divided into 10 groups, 10 people in each group, and the sunscreen creams of Examples 1-4, 7-10 and Comparative Examples 1-2 were respectively used.

[0129] Volunteer inclusion criteria: 1) healthy, without any skin disease or systemic disease history; 2) male and female, aged 18-65 years old; 3) serious attitude, can insist on using the product; the excluded population is pregnant or lactating women, sensitive skin.

[0130] Method of use: after cleansing, apply the sunscreen cream at 2 mg / cm 2 The coating density is uniformly applied to the face, once a day, and the product is continuously used for 7 days.

[0131] The efficacy evaluation method is completed in the form of a questionnaire.

[0132] Main evaluation indexes:

[0133] Skin feel indexes: very dislike (sticky, not absorbed, heavy, etc., poor spreadability), general (slightly sticky, poor absorption, general spreadability), very good (no greasy feeling, refreshing, easy to absorb, good spreadability).

[0134] The percentage of user preference is used as the comparison basis, and the test results are shown in Table 2.

[0135] Table 2

[0136]

[0137]

[0138] From the data analysis of Table 2, the skin feel experience of the sunscreen creams of the application in Examples 1-3 is good, and the volunteers feel fresh and no greasy after use. As can be seen from Example 7, the use effect of the sunscreen cream is better after adding the skin feel regulator. As can be seen from Examples 8-10, the components in the skin feel regulator cooperate with each other, which can better improve the user satisfaction of the sunscreen cream. As can be seen from Comparative Examples 1-2, the skin feel experience of the sunscreen creams using pure chemical sunscreen agents or physical sunscreen agents is relatively poor. In Comparative Example 1, only chemical sunscreen agents are used. Since the chemical sunscreen agents are mostly oil-soluble raw materials, although oily substances can provide a certain moisturizing feeling, too much of them will bring certain negative effects (such as greasy feeling) to the use experience of the volunteers. In Comparative Example 2, the sunscreen agent is only a physical sunscreen agent, and the physical sunscreen agent is mostly a powder. The powder has a certain oil absorption. In the absence of oily sunscreen agents, the addition of high powder will make the skin feel dry and difficult to spread, so the skin feel of Comparative Example 2 will be significantly worse than that of other examples.

[0139] Safety evaluation of Test Example 3:

[0140] The sunscreen creams prepared in Examples 1-10 were subjected to safety test in this test example, and the test method was as follows:

[0141] The chorioallantoic membrane (CAM) is a respiratory membrane surrounding the chicken embryo. Since the surface of the chicken embryo allantoic membrane is rich in blood vessels, it can be regarded as a complete organism. In this test, the characteristics of the complete, clear and transparent blood vessel system of the mid-term chorioallantoic membrane of the hatched chicken embryo were utilized. A certain amount of test substance was directly contacted with the chicken embryo allantoic membrane, and the changes of the toxicity effect indicators (such as bleeding, coagulation and vascular fusion) of the chorioallantoic membrane were observed after a specified time of action. The scores were given, and the mathematical average value was calculated for evaluating the irritation of the test substance.

[0142] (1) Preparation of chicken embryo: fertilized chicken embryos of White Leghorn chicken and the like, with a weight of 50-60 g, were preferentially selected from SPF chicken embryos and placed in an egg incubator for hatching. The temperature was controlled at 37.5℃±0.5℃, the relative humidity was 55%-70%, and the egg turning frequency was 3-6 times / h. The eggs were checked by an egg illuminator on the 8th day of hatching, and the unfertilized and inactive chicken embryos were discarded. The chicken embryos with well-developed blood vessels were selected and marked on the air chamber position on the eggshell surface.

[0143] (2) Test procedure: At least 6 embryos per group, negative and positive controls were used in each test. The test was started on day 9. The shell of the egg was carefully removed with a dental forceps, and a few drops of physiological saline were added to the shell membrane surface to ensure sufficient wetting. After draining, the shell membrane was carefully removed with forceps, and the exposed allantoic membrane was ensured to be intact without any damage. 0.3 ml / 0.3 g of the test substance was directly applied to the CAM. The application was as extensive as possible to ensure that the area covered was at least 50%. After 3 min, the CAM surface was gently rinsed with double-distilled water, and the rinsing was completed within 30 s. The liquid was drained, and the degree of change in each toxic effect was observed immediately under a stereomicroscope. The score (ES) was given according to the degree of hemorrhage, coagulation and vascular fusion.

[0144] (3) Results observation:

[0145] Hemorrhage: blood flowed out from the blood vessels or capillaries of the CAM. According to no hemorrhage, mild hemorrhage, moderate hemorrhage and severe hemorrhage, 0, 1, 2 and 3 points were given, respectively.

[0146] Coagulation: refers to the denaturation of proteins inside and outside the blood vessels, which is manifested as thrombus, swelling of the vessel wall, appearance of coagulation points inside and outside the blood vessels, and opalescent turbidity outside the blood vessels. According to no coagulation, mild coagulation, moderate coagulation and severe coagulation, 0, 1, 2 and 3 points were given, respectively.

[0147] Vascular fusion: refers to the ablation of blood vessels on the CAM membrane. According to no vascular fusion, mild vascular fusion, moderate vascular fusion and severe vascular fusion, 0, 1, 2 and 3 points were given, respectively.

[0148] (4) Result calculation and evaluation

[0149] The average ES score was calculated according to the following formula, and the stimulation classification was determined according to Table 3.

[0150]

[0151] Table 3 Result evaluation

[0152] End point score Irritation classification ES≤12 No / mild irritation 12 < ES < 16 Moderate irritation ES≥16 Severe irritation

[0153] The test results are shown in Table 4:

[0154] Table 4

[0155] Group Irritation evaluation index ES Irritation classification Example 1 2 No / mild irritation Example 2 3 No / mild irritation Example 3 5 No / mild irritation Example 4 3 No / mild irritation Example 5 4 No / mild irritation Example 6 4 No / mild irritation Example 7 5 No / mild irritation Example 8 2 No / mild irritation Example 9 6 No / mild irritation Example 10 5 No / mild irritation

[0156] As shown by the data in Table 4, the sunscreen creams obtained from the specific components of the present application have no hemolytic phenomenon and are safe and non-irritating. It is determined that the products described in the present application have no adverse reactions on the human body and have high safety.

[0157] The applicant states that the present application is illustrated by the above examples of a light and stable high-multiple sunscreen cream and its preparation method, but the present application is not limited to the above detailed method, that is, it does not mean that the present application must rely on the above detailed method to be implemented. The skilled in the art should understand that any improvement of the present application, equivalent replacement of each raw material of the product of the present application, addition of auxiliary ingredients, selection of specific methods, etc. fall within the protection scope and disclosure scope of the present application.

Claims

1. A light, stable, high factor sunscreen emulsion, characterized in that, The components of the light and stable high-multiple sunscreen cream include 1-30 parts of chemical sunscreen agent, 1-10 parts of physical sunscreen agent, 1-10 parts of emulsifier, 1-15 parts of oil, 1-15 parts of moisturizing agent, and 30-99 parts of deionized water by weight; The chemical sunscreen agent is a combination of ethylhexyl methoxy cinnamate, diethyl amino hydroxy benzoyl hexyl benzoate, and methylene bis-benzotriazolyl tetramethyl butyl phenol; The light and stable high-multiple sunscreen cream further includes a plant sunscreen agent; The plant sunscreen agent is a combination of Laminariales extract and ergothioneine; The light and stable high-multiple sunscreen cream further includes a skin feel modifier; The skin feel modifier includes a combination of at least two of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, or silica.

2. The light-feeling stable high factor sunscreen emulsion according to claim 1, characterized in that, The mass ratio of ethylhexyl methoxy cinnamate, diethyl amino hydroxy benzoyl hexyl benzoate, and methylene bis-benzotriazolyl tetramethyl butyl phenol is (1-10):(0.2-8):(0.5-10).

3. The light-feeling stable high factor sunscreen emulsion according to claim 1 or 2, characterized in that, The physical sunscreen agent includes titanium dioxide and / or zinc oxide; The emulsifier includes any one or a combination of at least two of PEG-2 stearate, PEG-20 stearate, glyceryl stearate, potassium lauryl phosphate, sorbitan stearate, polyglyceryl-3 isostearate, methyl gluceth-20, isoceteth-20, cetostearyl alcohol, or C20-22 alkyl phosphate.

4. The light-feeling stable high factor sunscreen emulsion according to claim 1, characterized in that, The oil includes any one or a combination of at least two of cyclopentasiloxane, dimethicone, butylene glycol dicaprylate / dicaprate, neopentyl glycol diheptanoate, oleic acid / linoleic acid / linolenic acid polyglycerides, hydroxystearic acid, or squalane.

5. The light-feeling, stable, high SPF sunscreen emulsion of claim 1, wherein, The moisturizing agent includes any one or a combination of at least two of 1,3-propanediol, diglycerin, glucose, 1,2-hexanediol, sodium hyaluronate, or butylene glycol.

6. The light-feeling, stable, high SPF sunscreen emulsion of claim 1, wherein, The mass ratio of Laminariales extract and ergothioneine is 1:(1-2).

7. The light-feeling, stable, high SPF sunscreen emulsion of claim 1, wherein, The skin feel modifier includes a combination of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica.

8. The light-feeling, stable, high factor sunscreen emulsion according to claim 7, wherein The mass ratio of glycerin polymethyl acrylate, vinyl dimethicone / methicone silsesquioxane crosspolymer, and silica is (1-3):(0.5-1.5):(0.1-1).

9. The light-feeling, stable, high SPF sunscreen emulsion of claim 1, wherein, The light and stable high-multiple sunscreen cream further includes a thickening agent and / or a chelating agent.

10. The light-feeling, stable, high factor sunscreen emulsion of claim 9, wherein, The thickening agent includes acrylates / ethylhexyl decylcro s s-link at poly mer and / or xanthan gum.

11. The light-feeling, stable, high SPF sunscreen emulsion of claim 9, wherein the emulsion has a pH of 4.5 to 6.

5. The chelating agent includes disodium EDTA.

12. The light, stable, high factor sunscreen emulsion of claim 1, wherein, The light and stable high-multiple sunscreen cream further includes any one or a combination of at least two of preservative, pH adjuster, or fragrance.

13. The light, stable, high factor sunscreen emulsion of claim 1, wherein, The components of the stable high-multiple sunscreen cream include 1-20 parts of chemical sunscreen agent, 1-8 parts of physical sunscreen agent, 1-8 parts of plant sunscreen agent, 1-8 parts of emulsifier, 1-10 parts of oil, 1-10 parts of moisturizer, 1-5 parts of skin feel modifier, 0.1-1 parts of thickening agent, 0.05-0.2 parts of chelating agent, and 30-99 parts of deionized water.

14. The method of making a light weight, clear, stable, high SPF sunscreen emulsion according to any one of claims 1-13, wherein, The method comprises: (1) mixing part of the chemical sunscreen agent, the emulsifier, the oil, part of the skin feel modifier, and the physical sunscreen agent, and heating to 75-85°C to obtain phase A; (2) mixing the chelating agent, the thickening agent, part of the moisturizer, the remaining skin feel modifier, and half of the water, and heating to 75-85°C to obtain phase B; (3) mixing the remaining chemical sunscreen agent and the remaining water to obtain phase C; (4) mixing and homogenizing phase A and phase B, adding phase C, homogenizing, cooling to 45°C, adding the remaining moisturizer and the plant sunscreen agent, and mixing and homogenizing to obtain the sunscreen cream; The steps (1), (2), and (3) are not distinguished in order.

15. The method of claim 14, wherein the method is characterized by, After adding the plant sunscreen agent in step (4), any one or a combination of at least two of the preservative, the pH adjuster, or the fragrance is further added.

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